World Oral Care Formulation Patents Published in 2010

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PCT - WORLD PATENTS IN ORAL CARE PUBLISHED IN 2010


Title: PARA-XYLYLENE BASED MULTILAYER DRUG ELUTION DEVICES

Publication No: WO2010/151269
Pub. Date - Int. Class - Applicant: - 29.12.2010 - A61K 9/00 - BIOTIC LABORATORIES, INC.
This invention is in the field of controlled elution devices for therapeutic delivery. There exists a need for a stand-alone capable device for the localized and extended delivery of a therapeutic. This need is overcome by the present invention having an exemplary embodiment comprised of a microfilm base (12), a reservoir of a therapeutic (14) disposed about the microfilm base (12) and a top layer (24) that is (i) a plurality of laminated layers (24) of para-xylyelne polymer and/or (ii) para-xylyelne polymer endowed with oxidatively functionalized para-xyele units. The thicknesses of the device is optimally in the range of about 10 to about 200 microns. The device is usable for the localized release of broad spectrum therapeutics for interv...


Title: BONE-REPAIR COMPOSITION

Publication No: WO2010/150958
Pub. Date - Int. Class - Applicant: - 29.12.2010 - A61L 27/12 - CG BIO CO., LTD.
The present invention relates to a bone-repair composition comprising a micro-pulverized demineralized bone matrix; a nonmicro-pulverized demineralized bone matrix; and a hydrating material. The bone-repair composition of the present invention provides easier injectability and shape-maintenance (handling), and exhibits excellent bone-repairing effects due to a large surface area of the micro-pulverized demineralized bone matrix and an early release of the bone growth factors, compared with conventional compositions comprising the nonmicro-pulverized demineralized bone matrix alone. It also has an advantage of being biocompatible and harmless to the human body because there is no use of synthetic materials.


Title: COMPOSITION FOR THE MANAGEMENT AND IMPROVEMENT OF ORAL HEALTH

Publication No: WO2010/150944
Pub. Date - Int. Class - Applicant: - 29.12.2010 - A61K 31/357 - LIVECHEM, INC.
The present invention relates to a composition comprising dibenzo-p-dioxin derivatives as active ingredients for the management and improvement of oral health. The composition enables long-lasting freshness and cleanliness of one's oral cavity by effectively inhibiting the formation of biofilms and eliminating the biofilms which cause dental caries, tartars, halitosis (bad breath) and gum diseases. Moreover, the present invention provides effective maintenance and improvement of oral health by preventing dental caries and gum diseases, and improving them.


Title: PROCESS TO OBTAIN TOOTH-PASTE AND/OR MOUTH-WASH (ORAL ANTISEPTICS), CONTAINING ANTIOXIDANT NATURAL OR SYNTHETIC, AND ANTIOXIDANT OBTAINED FROM PLANTS RICH IN POLYPHENOLS, USED IN THE PREVENTION AND/OR IN THE TREATMENT OF PERIODONTAL DISEASES IN WICH THERE ARE AN INCREASE OF PRO-OXIDANTS FACTORS AND/OR FORMATION OF LARGE QUANTITIES OF REACTIVE OXYGEN SPECIES."

Publication No: WO2010/148464
Pub. Date - Int. Class - Applicant: - 29.12.2010 - A61K 36/82 - UNIVERSIDADE DO ESTADO DO RIO DE JANEIRO
The present invention deal with a process to obtain a tooth-paste and/or a mouth-wash containing antioxidants compounds obtained from plants that are rich in polyphenols, for the treatment or prevention of periodontal diseases where an increase in production of pro-oxidant compounds and/or for instant formation of large quantities of reactive oxygen species.


Title: POLYETHER GROUP CONTAINING DENTAL COMPOSITION CONTAINING AN F-CONTAINING COMPOUND, PROCESS OF PRODUCTION AND USE THEREOF

Publication No: WO2010/147817
Pub. Date - Int. Class - Applicant: - 23.12.2010 - A61K 6/093 - 3M INNOVATIVE PROPERTIES COMPANY
The invention relates to a curable dental composition comprising a curable polyether group containing polymer as component (A), an initiator capable of initiating a curing reaction of component (A) as component (B) and a certain F-containing compound as component (C). The invention also relates to a method of production and use of the curable dental composition or a respective kit of parts for the preparation of or as impression material or for the preparation of crowns and bridges.


Title: BUFFERED GUM BASE FOR HIGH PH RELEASE

Publication No: WO2010/145653
Pub. Date - Int. Class - Applicant: - 23.12.2010 - A23G 4/08 - FERTIN PHARMA A/S
The invention relates to a chewing gum composition with high pH-release, the chewing gum composition comprising an insoluble gum base matrix and a soluble bulk portion, wherein the gum base matrix and the bulk portion is mixed and extruded to form a final chewing gum core, and wherein the gum base matrix is buffered before mixing with the bulk portion. Furthermore, the invention relates to a method of producing a chewing gum core, wherein a gum base matrix and a bulk portion is mixed and extruded to form a final chewing gum core, and wherein the gum base matrix is buffered before mixing with the bulk portion, and the gum base matrix comprises a first amount of buffer from 2 to 20 percent by weight of the gum base matrix before mixing with t...


Title: SINGLE-USE TOOTHBRUSH HAVING A RESERVOIR OF TOOTHPASTE ASSOCIATED WITH THE HEAD

Publication No: WO2010/144938
Pub. Date - Int. Class - Applicant: - 23.12.2010 - A46B 11/02 - VASILJKOVIC, Zelko
A single-use toothbrush having a head and handle, bristles on one side of the head, a reservoir of toothpaste associated with the head the contents of which can be moved into connection with the bristles so that when the brush is to be used, the toothpaste may be moved from the reservoir to be in contact with the bristles from which it is spread into the users mouth. The handle of the toothbrush may be hollow and adapted to receive and retain mouthwash.


Title: EPOXY-CONTAINING COMPOSITION CURABLE BY MULTIPLE POLYMERIZATION MECHANISMS

Publication No: WO2010/144787
Pub. Date - Int. Class - Applicant: - 16.12.2010 - A61K 6/08 - PENTRON CLINICAL TECHNOLOGIES, LLC
Polymerizable compositions are provided that contain an epoxy compound and a polymerizable, ethylenically-unsaturated resin having an acid functional group where the epoxy compound is polymerized by cationic polymerization initiated by the acid functional group and the polymerizable, ethylenically-unsaturated resin is polymerized by free-radical polymerization. To that end, a two-part polymerizable composition is provided that has a first part containing the epoxy compound; and a second part containing the polymerizable, ethylenically-unsaturated resin having an acid functional group. The first part and/or the second part further contain a radical initiator effective to initiate either self-curing or light-curing by free-radical polymerizat...


Title: POLYURETHANE OLIGOMERS FOR USE IN RESTORATIVE DENTISTRY

Publication No: WO2010/143934
Pub. Date - Int. Class - Applicant: - 16.12.2010 - C08G 18/83 - UNIVERSITI MALAYA
A composition of dental filling materials comprising a urethane oligomer obtained from a reaction between natural oil-derived polyols and a diisocyanate in excess to create terminals of isocyanate groups, the oligomer being grafted with an unsaturated acrylic monomer having hydroxyl groups which could react with the isocyanate terminals, and the resulting dental material being curable by free radical initiation.


Title: DENTAL USES OF SILVER HYDROSOL

Publication No: WO2010/143075
Pub. Date - Int. Class - Applicant: - 16.12.2010 - A61K 33/38 - WILLOUGHBY, Andrew, J.m.
Microbiologically effective silver hydrosol is used to reduce the local level of microorganisms at the site of a dental procedure and to prevent or inhibit their growth during the healing that follows the procedure. Any gingival lesions created by a dental procedure are treated with silver hydrosol in an aqueous gel. Following the procedure the patient's mouth is periodically rinsed several times a day with a solution of silver hydrosol or, more preferably, with a combination of silver hydrosol and hydrogen peroxide. These steps result in a significant reduction in post operative pain and swelling. Overall healing is accelerated by this treatment.


Title: BORINIC COMPOSITIONS

Publication No: WO2010/141694
Pub. Date - Int. Class - Applicant: - 09.12.2010 - A61Q 11/00 - COLGATE-PALMOLIVE COMPANY
A stabilized topical composition comprising a borinic acid derivative, e.g., a borinic ester.


Title: BORINIC COMPOSITIONS

Publication No: WO2010/141693
Pub. Date - Int. Class - Applicant: - 09.12.2010 - A61Q 11/00 - COLGATE-PALMOLIVE COMPANY
A stabilized oral care composition comprising a borinic acid derivative, e.g., a borinic ester.


Title: ALGINATE OLIGOMERS FOR USE IN OVERCOMING MULTIDRUG RESISTANCE IN BACTERIA

Publication No: WO2010/139957
Pub. Date - Int. Class - Applicant: - 09.12.2010 - A61K 47/36 - ALGIPHARMA IPR AS
The invention provides a method of overcoming resistance to at least one antibiotic in a multidrug resistant bacterium, said method comprising contacting said bacterium with an alginate oligomer together with the antibiotic. The multidrug resistant bacterium may be on an animate or inanimate surface and both medical and non-medical uses and methods are provided. In one aspect the invention provides an alginate oligomer for use together with at least one antibiotic in treating a subject infected, suspected to be infected, or at risk of infection, with a multidrug resistant bacterium to overcome resistance to the antibiotic in said multidrug resistant bacterium. In another aspect the method can be used to combat contamination of a site with m...


Title: TREATMENT OF ACINETOBACTER WITH ALGINATE OLIGOMERS AND ANTIBIOTICS

Publication No: WO2010/139956
Pub. Date - Int. Class - Applicant: - 09.12.2010 - A61K 47/36 - ALGIPHARMA IPR AS
The invention provides a method to improve the efficacy of an antibiotic to inhibit the growth of Acinetobacter, said method comprising using said antibiotic together with an alginate oligomer. The Acinetobacter may be on an animate or inanimate surface and both medical and non-medical uses and methods are provided. In one aspect the invention provides an alginate oligomer for use together with at least one antibiotic in treating a subject infected, suspected to be infected, or at risk of infection, with Acinetobacter. In another aspect the method can be used to combat Acinetobacter contamination of a site e.g. for disinfection and cleaning purposes.


Title: A MEDICAL CLEANING KIT

Publication No: WO2010/139762
Pub. Date - Int. Class - Applicant: - 09.12.2010 - A61C 5/02 - STRAUMANN HOLDING AG
The present invention relates to the field of cleaning and/or conditioning of biological and dental implant surfaces. More particularly, the invention relates to a kit comprising a) a cleaning device said cleaning device (1) comprising: an elongated base member (2) formed of at least two wires (3) being twisted with each other, and a plurality of bristles (4) fixed between said twisted wires (3) and extending away from said twisted wires (3), whereby said bristles (4) are positioned in a cleaning section (5) at a first end (6) of said base member (2) wherein said bristles (4) consist of titanium or a titanium alloy; and b) a container comprising a composition comprising ethylene diaminotetraacetic acid (EDTA). The kit may be used for the cl...


Title: DENTIFRICE COMPOSITION

Publication No: WO2010/138492
Pub. Date - Int. Class - Applicant: - 02.12.2010 - A61K 8/21 - COLGATE-PALMOLIVE COMPANY
Disclosed are dentifrice compositions comprising an orally acceptable vehicle and at least one source of metal ions in a polymer matrix, the metal being selected from zinc, stannous, copper or combinations thereof, the at least one source of metal ions comprising from 10 to 75 wt% of the total weight of the polymer matrix and the at least one source of metal ions, and wherein the dentifrice composition comprises less than 10 wt% water based on the total weight of the dentifrice composition. Also disclosed is a method of stabilizing at least one source of metal ions in a dentifrice compositions.


Title: DENTAL RETRACTION COMPOSITION, METHOD OF PRODUCTION AND USE THEREOF

Publication No: WO2010/138433
Pub. Date - Int. Class - Applicant: - 02.12.2010 - A61C 9/00 - 3M INNOVATIVE PROPERTIES COMPANY
The invention features a composition which can or is to be used in a dental retraction, the composition comprising a liquid and a layer type 1:1 silicate mineral and a layer type 2:1 silicate mineral in a ratio from about 50/50 to 5/95 wt.-% with respect to each other. The invention also relates to a container containing the dental retraction composition and to a kit comprising parts A and B, wherein part A comprises the dental retraction composition and part B comprises at least one accessory selected from the group of applier, dental impression material, retraction cap(s), a container for storing and dispensing the composition and combinations thereof. The invention further features a process of dispensing a dental retraction composition,...


Title: ORAL COMPOSITIONS CONTAINING POLYGUANIDINIUM COMPOUNDS AND METHODS OF MANUFACTURE AND USE THEREOF

Publication No: WO2010/134904
Pub. Date - Int. Class - Applicant: - 25.11.2010 - A61K 6/027 - COLGATE-PALMOLIVE COMPANY
The invention describes the modification of polyamine-based materials to form polyguanidine compounds that are useful for their antimicrobial, anticaries, and muccoadhesive properties. The present invention also relates to methods for preventing or treating periodontal disease and caries which include delivering a therapeutically effective amount of an oral composition containing a polyguanidine compound into an oral cavity.


Title: ORAL COMPOSITION

Publication No: WO2010/134903
Pub. Date - Int. Class - Applicant: - 25.11.2010 - A61Q 11/00 - COLGATE-PALMOLIVE COMPANY
The present invention provides an oral composition comprising a polymer, preferably a copolymer of methyl vinyl ether and maleic anhydride, attached to a sweetening agent via a cleavable linker, comprising a covalent bond, preferably an ester bond or an amide bond wherein the polymer is capable of attaching to a surface in an oral cavity, and the cleavable linker is cleavable in the oral cavity to release the sweetening agent.


Title: PERSONAL BODY CLEANING DEVICE

Publication No: WO2010/134051
Pub. Date - Int. Class - Applicant: - 25.11.2010 - A63F 13/02 - BRAUN GMBH
The present invention concerns a personal hygiene device for personal use, in particular in the form of a toothbrush, with a hand-held hygiene tool (in particular a toothbrush), a base station for storing and/or charging the hygiene tool, and a display device to display interactive presentations that can be interactively controlled from the hygiene tool by means of a control device. According to the invention, the display device forms a module fashioned separately and separately positionable from the base station and the hygiene tool and possesses a communication interface for communication with the base station and/or with the hygiene tool, even when separated from these. By fashioning the display device as a standalone module, the display...


Title: INTEGRATED TOOTHBRUSH, TOOTHPASTE DISPENSER AND HOLDER WITH REFRESH CUP COVER

Publication No: WO2010/132590
Pub. Date - Int. Class - Applicant: - 18.11.2010 - B65D 35/28 - MCCOY, William
A combination toothbrush and toothpaste dispenser device includes a caddy that accepts tube of toothpaste and guides an integral toothpaste squeezer along a predetermined track. The squeezer is generally wedge-shaped and may be moved parallel and/or inwardly to the axis of the caddy. A modular and detachable toothbrush head mates with the caddy and includes a shaft with a central bore for delivering toothpaste to the toothbrush bristles. A refresh cup is further supplied to store and protect the combination device while not in use.


Title: SYSTEM, METHOD, PROCESS AND PRODUCT FOR CLEANING, WHITENING AND THERAPEUTIC SURFACE ENHANCEMENT, USING SONIC OR ULTRASONIC WAVES OR ACOUSTIC STREAMS

Publication No: WO2010/132496
Pub. Date - Int. Class - Applicant: - 18.11.2010 - A61C 1/16 - FLORMAN, Michael
The present disclosure describes systems, product kits, methods, processes and devices for using omni-sonic waves to clean, whiten, or enhance cleaning agent, whitening agent and medicament uptake, delivery, and efficacy on hard and soft tissues. In a first embodiment, a system for enhancing contact surfaces is disclosed including an omni-sonic energy source activated by a power source and an omni-sonic energy source tip having a length and a width.


Title: DENTAL ADHESIVE COMPOSITION COMPRISING ADHESION PROMOTING POLYMER ADDITIVE AND METHOD

Publication No: WO2010/132270
Pub. Date - Int. Class - Applicant: - 18.11.2010 - A61K 6/00 - 3M INNOVATIVE PROPERTIES COMPANY
Presently described are dental adhesive compositions and methods of use. The dental adhesive compositions described herein comprises a major amount of a hardenable component comprising a polymerizable organic component (i.e. having ethylenically unsaturated moieties) and a minor amount of a (e.g. water dispersible) polymer that comprises repeating units comprising polar or polarizable groups and repeating units comprising hydrophobic hydrocarbon groups.


Title: NOVEL COMPOSITION

Publication No: WO2010/130816
Pub. Date - Int. Class - Applicant: - 18.11.2010 - A61K 8/19 - GLAXO GROUP LIMITED
Electrospun polymer fibres comprising an amorphous calcium compound, oral care compositions comprising such fibres and their use in remineralising dental hard tissues and/or blocking dentinal tubules are described. Such compositions are of use in strengthening dental enamel of teeth thereby providing protection from acidic challenges. Such compositions are of use in combating dental erosion and/or tooth wear. Such compositions are of use in combating dental caries. Such compositions are of use in combating dentine hypersensitivity.


Title: MICROENCAPSULATED COMPOSITIONS AND METHODS FOR TISSUE MINERALIZATION

Publication No: WO2010/129309
Pub. Date - Int. Class - Applicant: - 11.11.2010 - A61K 8/18 - PREMIER DENTAL PRODUCTS COMPNAY
The present invention is directed to compositions, products and methods useful for bone and tooth mineralization. The compositions comprise polymer microcapsules containing aqueous salt solutions. The shells of the microcapsules can be semi- permeable or impermeable. Solutions of calcium, fluoride and phosphate salts are particularly useful in the compositions of the invention. The microcapsules are preferably prepared by surfactant free inverse emulsion interfacial polymerization. Bone products include cements, scaffolds and bioactive glass. Dental products include pastes, gels, rinses and many other dental materials.


Title: COMPOSITE COMPOSITION

Publication No: WO2010/127106
Pub. Date - Int. Class - Applicant: - 04.11.2010 - C08K 3/00 - TUNDRA COMPOSITES, LLC
The invention relates to a nonmetallic inorganic or mineral particulate polymer composite having enhanced viscoelastic and rheological properties.


Title: COMPOSITE COMPOSITION

Publication No: WO2010/127101
Pub. Date - Int. Class - Applicant: - 04.11.2010 - C08K 9/04 - TUNDRA COMPOSITES, LLC
The invention relates to a ceramic particulate and polymer composite having enhanced viscoelastic and rheological properties.


Title: METHODS AND COMPOSITION FOR TREATING A MATERIAL

Publication No: WO2010/126565
Pub. Date - Int. Class - Applicant: - 04.11.2010 - A01N 31/00 - URTHTECH, LLC
A composition and method are described for sanitizing or otherwise treating a material such as a non-living surface, living tissue, soil or atmosphere which may be contaminated by a toxin, chemical warfare agent, insect, prion, microorganism or other infectious agent. The composition generally includes an aqueous composition mixture that includes: (a) lower alkanol; (b) an alkalinating agent, and (c) a fatty acid salt and/or ester. The components are present in an effective amount to sanitize (or treat) a material (or modifying a chemical contained thereon) to which the composition is applied. Also described are methods of making the composition.


Title: SELECTIVELY PERMEABLE PROTECTIVE STRUCTURE AND ARTICLES THEREFROM

Publication No: WO2010/124051
Pub. Date - Int. Class - Applicant: - 28.10.2010 - B32B 27/12 - E. I. DU PONT DE NEMOURS AND COMPANY
A selectively permeable protective structure and a method for limiting damage to the article due to corrosion or mold growth, comprising wrapping or covering the article in the selectively permeable protective structure. The selectively permeable structure comprises a membrane having a moisture vapor permeation value of at least 200 g-mil/m2/24h and barrier to liquid water, and optionally a supporting substrate. The membrane comprises an organic acid-modified ionomer, an ethylene/ (meth) acrylic/alkyl (meth) acrylate terpolymer and optionally an ethylene polymer.


Title: DENTAL CLEANING DEVICE

Publication No: WO2010/122335
Pub. Date - Int. Class - Applicant: - 28.10.2010 - A46B 9/04 - MOSTAFA, Hani Mostafa Awadalla
A dental cleaning device (10) comprising cleaning elements (12) arranged in a spaced relationship and angled generally towards one another such that a space (14) is defined there between. The cleaning elements (12) being movable to increase the space (14) to thereby enable the cleaning elements (12) to be located on either side of part of a tooth. Each cleaning element (12) acts to control the angle of the other cleaning element (12) relative to the tooth and gum, to ensure that the cleaning elements (12) engage the tooth and gum at an angle, so that the cleaning elements (12) can clean between the tooth and the gum.


Title: HEAT TRANSFER COMPOSITIONS

Publication No: WO2010/119265
Pub. Date - Int. Class - Applicant: - 21.10.2010 - C08J 9/14 - MEXICHEM AMANCO HOLDING S.A. de C.V.
The invention provides a heat transfer composition comprising: (i) 1,3,3,3-tetrafluoroprop-1-ene (R1234ze, CF3CH=CHF) (ii) a second component comprising R-1243zf, (3,3,3 trifluoropropene) or a difluoropropene (R-1252) selected from R-1252zf, R-1252yf, R-1252ye R- 1252ze and R-1252zc, and mixtures thereof; and (iii) a third component selected from R32 (difluoromethane), R744 (CO2), R41 (fluoromethane), R1270 (propene), R290 (propane), R161 (fluoroethane) and mixtures thereof.


Title: DIMENSIONALLY STABLE NONWOVEN FIBROUS WEBS AND METHODS OF MAKING AND USING THE SAME

Publication No: WO2010/117612
Pub. Date - Int. Class - Applicant: - 14.10.2010 - D04H 1/42 - 3M INNOVATIVE PROPERTIES COMPANY
Dimensionally stable nonwoven fibrous webs include a multiplicity of continuous fibers formed from one or more thermoplastic polyesters and polypropylene in an amount greater than 0% and no more than 10% by weight of the web. The webs have at least one dimension which decreases by no greater than 10% in the plane of the web when heated to a temperature above a glass transition temperature of the fibers. When the thermoplastic polyester is selected to include aliphatic and aromatic polyesters, a spunbond process may be used to produce substantially continuous fibers that exhibit molecular orientation. When the thermoplastic polyester is selected from aliphatic polyesters, a meltblown process may be used to produce discontinuous fibers that d...


Title: DUAL ACTION DENTIFRICE COMPOSITIONS TO PREVENT HYPERSENSITIVITY AND PROMOTE REMINERALIZATION

Publication No: WO2010/115039
Pub. Date - Int. Class - Applicant: - 07.10.2010 - A61K 8/19 - COLGATE-PALMOLIVE COMPANY
The invention encompasses combinations of bioactive glass composition and potassium salts that are useful in conjunction with delivery agent such as, for example, toothpastes, mouthwashes, and oral gels. In certain embodiments, the compositions of the invention form a rapid and continuous reaction with body fluids (e.g., saliva) to promote the immediate and long- term release of Ca and P ions to produce a stable crystalline layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity and tooth surface remineralization.


Title: DEGRADABLE POLYMER COMPOSITIONS AND USES THEREOF

Publication No: WO2010/114761
Pub. Date - Int. Class - Applicant: - 07.10.2010 - C08L 77/00 - ISP INVESTMENT INC.
The invention relates to novel polymers derived from: (A) at least one N-vinyl amide-based unit and/or at least one acrylamide-based unit, and (B) at least one unit comprising: (i) at least one hydroxyl group, and/or (ii) at least one functional group convertible to a hydroxyl group wherein at least one group is converted to hydroxyl functionality in the final polymer product, wherein the polymer comprises at least one ester group. The polymers and compositions are used in oilfield applications, such as an inhibitor of gas hydrates and/or a kinetic inhibitor of gas hydrates. The polymer can assume alternating, block, and/or random configurations of the repeating units, with at least one ester group.


Title: NEW RESIN SYSTEMS FOR DENTAL RESTORATIVE MATERIALS

Publication No: WO2010/114760
Pub. Date - Int. Class - Applicant: - 07.10.2010 - A61K 6/087 - THE REGENTS OF THE UNIVERSITY OF COLORADO
The disclosure provides a new photopolymerizable resin system for dental restorative materials. The resin system utilizes a thiol-ene component as the reactive diluent in dimethacrylate systems. The ternary resin system comprises a thiol monomer, an ene monomer and a dimethacrylate monomer. Use of an off- stoichiometric ratio of thiol:ene functional groups in favor of excess thiols results in enhanced overall functional group conversion, improved polymer mechanical properties, and reduced shrinkage stress of the ternary system when compared to either traditional dimethacrylate or thiol-ene resin systems.


Title: EXFOLIATING DENTIFRICE COMPOSITION AND METHOD OF USE

Publication No: WO2010/114549
Pub. Date - Int. Class - Applicant: - 07.10.2010 - A61K 8/25 - COLGATE-PALMOLIVE COMPANY
An exfoliating dentifrice composition is described that contains a plurality of granules and an orally acceptable vehicle. The granules include at least one polymeric binding agent. The composition includes at least one abrasive agent having an average particle diameter of 0.01 mm to 4 mm. Also included are methods of exfoliating an oral cavity soft tissue by use of the composition.


Title: DENTIFRICE COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING DAMAGE TO TOOTH SURFACES

Publication No: WO2010/114540
Pub. Date - Int. Class - Applicant: - 07.10.2010 - A61K 8/44 - COLGATE-PALOLIVE COMPANY
The invention encompasses compositions and methods for treating and modifying surfaces of teeth, which compositions include calcium and magnesium containing silicates or silica, cationic polymer modified silica or combinations thereof. The composition when applied to the teeth or a tooth surface deposit on such surfaces to repair acid damaged enamel and prevent further erosion of a tooth surface.


Title: DESENSITIZING DENTIFRICE EXHIBITING DENTAL TISSUE ANTIBACTERIAL AGENT UPTAKE

Publication No: WO2010/114538
Pub. Date - Int. Class - Applicant: - 07.10.2010 - A61K 8/34 - COLGATE-PALMOLIVE COMPANY
An oral composition exhibiting increased uptake by dental tissue of antibacterial compounds contained therein and eliminating or substantially reducing the discomfort and pain associated with dentinal hypersensitivity. The composition includes an orally acceptable vehicle for such composition, an effective therapeutic amount of an antibacterial compound, a mixture of anionic surfactant and amphoteric surfactant, the mixture having 0.1 wt. % to 2.0 wt. % anionic surfactant and 0.8 wt. % to 2.0 wt. % amphoteric surfactant, and a potassium ion releasable compound.


Title: OLIGOMERIC OR POLYMERIC MATERIALS, PROCESSES FOR PREPARING THE SAME, COATINGS AND COATED PRODUCTS COMPRISING SUCH MATERIALS

Publication No: WO2010/112911
Pub. Date - Int. Class - Applicant: - 07.10.2010 - A61L 31/10 - THE UNIVERSITY OF SHEFFIELD
The invention relates to an article having a substantially non-cell adhesive surface and comprising on said surface a coating effective to render the article cell adhesive, wherein the coating comprises an oligomer having terminal amine functionality or peptide, peptide analogue or peptide derivative functionality and further relates to a coating composition for coating such an article.


Title: ANTIBACTERIAL COMPOSITION COMPRISING 4 -ISOPROPYL-3-METHYLPHENO AND ZINC IONS

Publication No: WO2010/112577
Pub. Date - Int. Class - Applicant: - 07.10.2010 - A61K 31/05 - GLAXO GROUP LIMITED
A composition such as an oral care composition comprising an antibacterial system comprising 4-isopropyl-3 -methyl phenol (IPMP), a source of zinc ions and an anionic surface active agent is described.


Title: COMPOSITION FOR ATTACHING A DENTAL FACING ON A DENTAL SUPPORT STRUCTURE, PROCESS AND USE THEREOF

Publication No: WO2010/104673
Pub. Date - Int. Class - Applicant: - 16.09.2010 - A61K 6/00 - 3M INNOVATIVE PROPERTIES COMPANY
The present invention relates to a composition for attaching a dental facing on a dental support structure comprising water, a glass and/or glass ceramic material, a rheological modifier with a molecular weight above about 500,000. The invention also relates to a process comprising the steps: providing a dental facing precursor and a dental support structure, both having an upper and a lower surface, attaching the dental facing precursor with its lower surface to the upper surface of the dental support structure, comprising the step of placing a mating composition between the lower surface of the dental facing precursor and the upper surface of the dental support structure and to the use of the inventive composition for producing dental res...


Title: DENTAL COMPOSITION

Publication No: WO2010/102786
Pub. Date - Int. Class - Applicant: - 16.09.2010 - A61K 6/083 - DENTSPLY DETREY GMBH
An aqueous dental glass ionomer composition comprising (a) a reactive particulate glass, and (b) a linear or branched polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, whereby the linear or branched polymer comprising acidic groups has a polymer backbone and optionally pendant side chains, (c) optionally dispersed nanoparticles, and (d) optionally a low molecular compound, characterized in that the glass ionomer composition comprises -SxH groups, wherein x is an integer of from 1 to 6, which crosslink the particulate glass and/or the linear polycarboxylic acid and/or the optional dispersed nanoparticles and/or the optional low molecular compound.


Title: ENHANCING COAGULATION OR REDUCING FIBRINOLYSIS

Publication No: WO2010/102216
Pub. Date - Int. Class - Applicant: - 10.09.2010 - A61K 31/69 - THE UAB RESEARCH FOUNDATION
Methods for controlling bleeding (e.g., enhancing coagulation and reducing fibrinolysis) in a subject are disclosed. The methods include selecting a subject in need of enhanced coagulation or reduced fibrinolysis, and administering to the subject a carbon monoxide releasing molecule (CORM). Examples of CORMs include tricarbonyldichloro-ruthenium (II) dimer, tricarbonylchloro-(glycinato)ruthenium (II), sodium boranocarbonate, dimanganese decacarbonyl, and iron pentacarbonyl. Further disclosed are compositions and methods for treating a subject in need of a blood product by administering to the subject a composition including a CORM and a blood product (e.g., cryoprecipitate or fresh frozen plasma).


Title: ANTI-VIRAL AND ANTI-MICROBIAL DENTAL OPERATIVE MATERIAL AND METHODS

Publication No: WO2010/102075
Pub. Date - Int. Class - Applicant: - 10.09.2010 - A61C 3/00 - ULTRADENT PRODUCTS, INC.
An anti-microbial and/or anti-viral composition for use in disinfecting an oral tissue during a dental procedure includes at least one dental operative material that is allowed to contact the oral tissue for a period of time and an effective amount of an anti-viral and/or anti -bacterial agent included in or mixed with the dental operative material so as to impart an antibacterial and/or anti-viral effect at or near a site of administration in oral tissue. The anti-viral and/or anti-bacterial agent at least partially at least partially contributes to at least a two-log reduction in viral and/or bacterial activity at or near a site of administration. The compositions protect a dental practitioner and/or other patient from being infected by a...


Title: SELF-FORMING GEL SYSTEM FOR SUSTAINED DRUG DELIVERY

Publication No: WO2010/100179
Pub. Date - Int. Class - Applicant: - 10.09.2010 - A61K 9/19 - NOVARTIS AG
Antibody formulations, and methods for their manufacture, which (i) are capable of preserving an antibody in a native and therapeutically active state while achieving a depot effect without the use of polymers or other complex formulation, reagents and (ii) provide very high loading capacity, thus offering the potential for increased dose per application to patient. These formulations take the form of a gel and are based on the surprising finding that some monoclonal antibodies have a gelation property under appropriate conditions.


Title: CAST MOUNTING FOR ARTICULATOR

Publication No: WO2010/099308
Pub. Date - Int. Class - Applicant: - 02.09.2010 - A61C 11/00 - GAMBACORTA, Enzo
A mechanical interfitting connector for repeatably connecting dental models of teeth to articulators without damaging the former. The connector may comprise a socket mountable to a model and a male member mountable to the articulator, wherein the male member enters and engages the socket. The socket may be adhered to the model or alternatively partially embedded therein. A screw may be passed through the socket and male member so as to leave a small marking on the dental model, thereby indexing the socket and model for subsequent mountings, and also to prevent disengagement of the male member from the socket. A supplementary plate may be provided to secure anchoring of the male member to the socket, and to shield plaster which has not fully...


Title: COMPOSITION

Publication No: WO2010/094975
Pub. Date - Int. Class - Applicant: - 26.08.2010 - A61K 8/02 - COSMETIC WARRIORS LTD
The present invention provides a surfactant product in the form of a solid comprising a surfactant, sodium carbonate and cream of tartar.


Title: OSSEOUS REGENERATION MATERIAL FROM COMBINATIONS OF MONETITE WITH OTHER BIOACTIVE CALCIUM COMPOUNDS

Publication No: WO2010/094813
Pub. Date - Int. Class - Applicant: - 26.08.2010 - A61L 27/12 - AZUREBIO, S. L.
The present invention incorporates new materials for osseous regeneration, the method of obtainment thereof, and application in trauma surgery, maxillofacial surgery, dental surgery, orthognathic surgery, endodontics, ophthalmology, neurosurgery and/or osteoporotic processes and other indications wherein bone regeneration is necessary. In particular the present invention incorporates synthetic materials having 20% to 95%, preferably between 40% and 90%, by weight of monetite [Ca1-xMxHPO4, where 0 = x = 0.05, and where M may be a divalent metal ion] which in the final composition thereof incorporates between 5% and 80%, preferably between 10% and 60%, by weight of bioactive calcium compounds selected from among phosphates, calcium silica...


Title: VIBRATING DENTAL PLATE AND ACCESSORIES

Publication No: WO2010/093632
Pub. Date - Int. Class - Applicant: - 19.08.2010 - A61C 3/00 - LEVENS, Lawrence
Vibrating dental devices and accessories are provided, including a unique snap fit dental plate and vibrator connection; risers for adjusting the thickness of a dental plate; a pointer or wand that can be clamped onto a dental plate to reach even severely misaligned teeth; a cushioned dental plate having a non-Newtonian fluid therein that allows conformation of the cushion to the dentition, but hardens on use to allow the transmission of vibration to the teeth. Accessories such as carrying cases and docking stations are also provided.


Title: BONE REGENERATION MATERIALS BASED ON COMBINATIONS OF MONETITE AND OTHER BIOACTIVE CALCIUM AND SILICON COMPOUNDS

Publication No: WO2010/092001
Pub. Date - Int. Class - Applicant: - 19.08.2010 - A61L 27/12 - AZUREBIO, S. L.
The present invention incorporates new materials for bone regeneration, methods for their manufacture, and application in traumatology surgery, maxillofacial surgery, dental surgery, orthognatic surgery, endodontics, ophthalmology, neurosurgery and/or osteoporotic processes, and other indications where bone regeneration is required. In particular, the present invention incorporates synthetic materials with a 20 % to a 95 %, preferably between 40% and 90% in mass of monetite [Ca1-XMXHPO4, where 0 = x = 0.05, and where M can be a divalent metallic ion], and which in their final composition incorporate between 5 % and 80 %, preferably between 0 % and 60 %, in mass of bioactive calcium compounds chosen from calcium phosphates and between 5%...


Title: ORAL CARE COMPOSITION TO REDUCE OR ELIMINATE DENTAL SENSITIVITY

Publication No: WO2010/090855
Pub. Date - Int. Class - Applicant: - 12.08.2010 - A61Q 11/00 - COLGATE-PALMOLIVE COMPANY
The invention includes an oral care composition that reduces and/or eliminates the perception of tooth sensitivity. The composition includes an adherent material and includes, in part, particles having a particle size of 2-5 microns. Also included within the scope of the invention are methods comprising the use of such compositions, such as methods of reducing dental sensitivity.


Title: TRANSDERMAL PHARMACEUTICAL PREPARATIONS

Publication No: WO2010/089617
Pub. Date - Int. Class - Applicant: - 12.08.2010 - A61K 9/06 - EGIS GYÓGYSZERGYÁR NYILVÁNOSAN MÜKÖDÖ RÉSZVÉNYTÁRSASÁG
The present invention relates to semisolid transdermal pharmaceutical preparation having enhanced stability and bioavailability, wherein the particles are coated by a volatile silicon oil component and the thus obtained suspension is dispersed in a gel or cream base.


Title: HYBRID POLYMER NETWORK COMPOSITIONS FOR USE IN DENTAL APPLICATIONS

Publication No: WO2010/087954
Pub. Date - Int. Class - Applicant: - 05.08.2010 - A61K 6/083 - DENTSPLY INTERNATIONAL INC.
A dental appliance comprising a hard, shaped body having at least one portion comprising a polymerized blend of: From 0% to about 50% of an uncrosslinked polymer capable of dissolving in component;From about 0% to 50% of a mono functional polymerizable monomer;From about 0% to 40% of a highly crosslinked polymer in the form of ground particles having average diameters up to about 500 microns;From about 0% to 50% of a crosslinked polymer in the form of discrete particles having average diameters up to about 500 microns and being easily swellable by said monomer; and From about 5% to about 35% of a di- or polyfunctional crosslinking agent.


Title: IMPLANTABLE MEDICAL DEVICES COMPRISING BIO-DEGRADABLE ALLOYS

Publication No: WO2010/080932
Pub. Date - Int. Class - Applicant: - 15.07.2010 - A61L 27/04 - BIO DG, INC.
The invention provides medical devices comprising high-strength alloys which degrade over time in the body of a human or animal, at controlled degradation rates, without generating emboli. In one embodiment the alloy is formed into a bone fixation device such as an anchor, screw, plate, support or rod. In another embodiment the alloy is formed into a tissue fastening device such as staple. In yet another embodiment, the alloy is formed into a dental implant or a stent.


Title: ANTISENSE COMPOSITIONS AND METHODS FOR MODULATING CONTACT HYPERSENSITIVITY OR CONTACT DERMATITIS

Publication No: WO2010/080554
Pub. Date - Int. Class - Applicant: - 15.07.2010 - C12N 15/113 - AVI BIOPHARMA, INC.
Provided are methods and compositions, including topical compositions, for inducing tolerance to a sensitizing agent known to provoke contact hypersensitivity in a subject. Included are methods of topically applying to the subject an effective amount of an antisense composition targeting the start site or splice site of a CFLAR mRNA.


Title: BIOACTIVE COMPOSITES OF POLYMER AND GLASS AND METHOD FOR MAKING SAME

Publication No: WO2010/077948
Pub. Date - Int. Class - Applicant: - 08.07.2010 - A61F 2/28 - ORTHOVITA, INC.
The present invention generally relates to bioactive composites of polymer and glass and, more particularly, to bioactive implants. The present invention also relates to methods of manufacturing bioactive composites. The bioactive composite finds utility in a variety of load-bearing clinical applications including spine, orthopaedic and dental procedures.


Title: COMPOSITIONS AND METHODS FOR IMPROVED ORAL HEALTH

Publication No: WO2010/077795
Pub. Date - Int. Class - Applicant: - 08.07.2010 - A61K 35/74 - ROUGHEAD, Zamzam, Kabiry
Compositions and methods for preventing and treating illnesses associated with oral health are provided. In a general embodiment, the compositions and methods of the present disclosure can improve oral health by reducing the incidence of aspiration pneumonia, community-acquired pneumonia and nosocomial pneumonia, allowing for less gingivitis and plaque, and providing improved tongue flora. By utilizing probiotics naturally present in the oral cavity or gastrointestinal tract, the compositions and methods in embodiments of the present disclosure can reduce anaerobic gram-negative bacilli and increase the presence of the normal flora. By preventing and treating problems associated with oral health in a patient, subsequent health problems can ...


Title: PAPER TUBE PACKAGING WITH OPEN END AND COATED CAP

Publication No: WO2010/077777
Pub. Date - Int. Class - Applicant: - 08.07.2010 - B65D 35/14 - WEST, Ellery
A biodegradable tube (100) comprises a non-rigid paper tubular body (110) defining a lumen for containing a semi-solid composition (150); a paper tubular cap (120) that slidably mates with the body (110); and wherein interior surfaces of the each of the body (110) and the cap (120) have a coating that is substantially impermeable to the semi-solid composition (150) In preferred embodiments the tube body and cap have tapered sealed ends (132, 134), the coating comprises an adhesive, and the walls of the tube/cap comprise a rolled paper material upon which the coating has been applied. Contemplated semi-solid product materials (150) include for example lip balm, facial cream, lotion, deodorant, sunscreen, caulk, grease sticks, mosquito repell...


Title: PRESSURIZED VALVE SYSTEM FOR DRIVING BRISTLE TUFTS

Publication No: WO2010/076702
Pub. Date - Int. Class - Applicant: - 08.07.2010 - A61C 17/38 - KONINKLIJKE PHILIPS ELECTRONICS, N.V.
The dental cleaning appliance includes an appliance body (30, 73) which has a bristle field housing (32, 52) and fluid within the housing. A flexible membrane (34) is positioned within the housing, or in a fluid-tight relationship (54) within an opening (60) in the housing. A fluid pressure system involving either a dual piston system (22, 24, 28) or a pump and valve system (70, 68, 68) provides pressure on the fluid, wherein the pistons move alternately, or the valves open and close alternately, in such a manner to produce alternating pressure above and beneath the membrane, moving the membrane and the bristle field toward and away from the teeth.


Title: POWER DENTAL CLEANING APPLIANCE WITH ACTUATOR SYSTEM FOR PRODUCING A SHORT BRISTLE STROKE

Publication No: WO2010/076696
Pub. Date - Int. Class - Applicant: - 08.07.2010 - A61C 17/30 - KONINKLIJKE PHILIPS ELECTRONICS, N.V.
One embodiment of an actuator system for a power dental cleaning appliance to produce a tapping motion of bristle tufts in a dental cleaning appliance includes a plurality of piston elements (16) mounted in a brushhead for movement away from and then toward the brushhead (12). Bristle tufts (20) are positioned on the piston elements and move sequentially against and away from the teeth to produce a cleaning action. A low frequency fluid pressure action (40) in the range of 1-6 Hz maintains conformity of the bristle tufts in a low frequency sequence against the teeth, while a higher frequency fluid pressure action (42) in the range of 100-300 Hz moves the bristle tufts at that frequency to produce a tapping bristle action on the teeth to pro...


Title: NON-PRESSURIZED SYSTEM FOR CREATING LIQUID DROPLETS IN A DENTAL CLEANING APPLIANCE

Publication No: WO2010/076694
Pub. Date - Int. Class - Applicant: - 08.07.2010 - A61C 1/00 - KONINKLIJKE PHILIPS ELECTRONICS, N.V.
The appliance (10, Figure 1) includes a body portion (27) and a nozzle portion (30) through which a spray of liquid droplets exits from a distal end thereof for cleaning of dental regions. The nozzle includes an orifice (36) at a proximal end thereof adjacent the body portion, as well as a pump (38) for moving liquid into an area of the nozzle just forward of the orifice. A mechanical system (12, 13, 14) is provided for moving a plunger or piston element (16) first away from the orifice under tension, such as a compression spring(24), and then controllably releasing the plunger or piston toward the orifice, the plunger/piston moving with sufficient force that atmospheric air which has been drawn into the appliance between the plunger or pis...


Title: DENTAL CLEANING MOUTHPIECE WITH REPLACEABLE BRISTLE FIELDS

Publication No: WO2010/076693
Pub. Date - Int. Class - Applicant: - 08.07.2010 - A61C 17/22 - KONINKLIJKE PHILIPS ELECTRONICS, N.V.
The dental mouthpiece includes an assembly (14, 16, 18) for holding a bristle field or fields (20) used to clean teeth when the mouthpiece is actuated, and a power assembly (12) for moving the bristle -holding structure and the bristle fields so that the bristles produce a cleaning action on the teeth, wherein the bristle fields are replaceable.


Title: NANOSTRUCTURED CALCIUM-SILVER PHOSPHATE COMPOSITE POWDER, METHOD FOR OBTAINING SAME, AND BACTERICIDAL AND FUNGICIDAL USES THEREOF

Publication No: WO2010/072882
Pub. Date - Int. Class - Applicant: - 01.07.2010 - B22F 9/24 - CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC)
The invention relates to a nanostructured calcium-silver phosphate composite powder which can be used as a bactericide and/or fungicide, with similar effectiveness to that of commercial products and with low toxicity. The invention also relates to a method for obtaining said nanostructured calcium-silver phosphate composite powders, which comprises preparing nanometric calcium phosphate by means of a sol-gel process and subsequently depositing silver nanoparticles on the surface thereof. Said nanostructured powder can be used for the production of a bactericide and/or fungicide composition suitable for use as an all-purpose disinfectant to be used, for example, in surgical implants, public facilities, food, dentistry, paints, clothes and pa...


Title: DENTAL FLUOROSCOPIC IMAGING SYSTEM

Publication No: WO2010/071680
Pub. Date - Int. Class - Applicant: - 24.06.2010 - A61B 6/14 - UZBELGER FELDMAN, Daniel
The dental fluoroscopic imaging system includes a flat panel detector comprised by a gamma-rays or x-rays converter, a plate, a collector, a processing unit and a transmitter suitable for 2D intraoral/extraoral and 3D extraoral dental fluoroscopy. The x-ray converter contains a material capable of transforming the low dose gamma rays or x-rays beam received from an emitter after going through the dental examination area into electrical signals or a light image consequent with the radiographed image. The plate transmits the electric signals or light image to a collector which amplifies it and sends it to a processing unit and then to transmitter designed to transfer digital images sequentially to a host computer and software which can acquir...


Title: ORAL CARE COMPOSITIONS WITH FUSED SILICA

Publication No: WO2010/068474
Pub. Date - Int. Class - Applicant: - 17.06.2010 - A61Q 11/00 - THE PROCTER &GAMBLE COMPANY
An oral care composition comprising a fused silica abrasive and an orally-acceptable carrier.


Title: DENTAL LIGHT DEVICE

Publication No: WO2010/068435
Pub. Date - Int. Class - Applicant: - 17.06.2010 - A61C 13/15 - 3M INNOVATIVE PROPERTIES COMPANY
A light device for curing a dental composition, comprising a light-source, a housing, a passive heat sink, first and second thermal pathways enabling heat transfer between the light source and the heat sink as well as between the heat sink and the housing. The first thermal pathway is dominated by thermal conduction, and the second thermal pathway is dominated by thermal radiation and thermal convection. The invention helps to provide an inexpensive and compact design of the device.


Title: METHOD AND DEVICE FOR MEASURING THE EFFICACY OF PLAQUE REMOVAL

Publication No: WO2010/067270
Pub. Date - Int. Class - Applicant: - 17.06.2010 - G06T 7/00 - BRAUN GMBH
The invention relates to a method for measuring the efficacy of a dental care product with regard to plaque removal on the teeth of a volunteer, comprising the following steps: a) requesting selection of a plaque index system; b) requesting selection of a model tooth to be examined and display of the selected model tooth on the display device; and c) input of the plaque data on the model tooth displayed on the display device according to the selected plaque index. Steps b) and c) are repeated for all of the volunteer's teeth. For each tooth, the percentage amount of plaque is determined, wherein the percentage amount of plaque corresponds to the area of the tooth surface covered with plaque according to the selected plaque index in relation...


Title: BIOSURFACTANT COMPOSITION PRODUCED BY A NEW BACILLUS LICHENIFORMIS STRAIN, USES AND PRODUCTS THEREOF

Publication No: WO2010/067245
Pub. Date - Int. Class - Applicant: - 17.06.2010 - C07K 14/32 - PAN-ECO S.A.
New Bacillus licheniformis strain named V9T14 that produces a new biosurfactant composition that is effective against colonization and/or bio film formation from bacteria. The new biosurfactant composition can be used in combination with biocides for preventing formation and/or for eradicating bacteria grown planktonically and/or as a biofilm, preferably on biotic and/or abiotic surfaces.


Title: DISPOSABLE TOOTHBRUSH WITH INTEGRAL TOOTHPASTE

Publication No: WO2010/066925
Pub. Date - Int. Class - Applicant: - 17.06.2010 - A46B 9/04 - SERRANO VENTAJA, Marcel
The present invention relates to a toothbrush that incorporates, in the structure thereof, toothpaste for a single use. The external appearance of the invention is that of a folded toothbrush. The bristles are on the handle and connected thereto by a resistant, but malleable, piece of material, the impelling cylinder, which on the handle side is fixed. At the base of the bristles, there is a hollow reservoir containing the paste and connected to the impeller cylinder by means of a sliding stop that will act as a push device to enable the paste to emerge at the base of the bristles by means of one or more hollows therein. The method for extracting the paste is mechanical and comprises simply the movement of opening out the brush. When the br...


Title: NOVEL USE

Publication No: WO2010/066655
Pub. Date - Int. Class - Applicant: - 17.06.2010 - A61K 8/21 - GLAXO GROUP LIMITED
A oral care composition comprising a triple polymer system and a source of fluoride ions for combating (i.e. helping to prevent, inhibit and/or treat) dental erosion and/or tooth wear is described. Such compositions are also of use in combating dental caries.


Title: HEAT TRANSFER COMPOSITIONS

Publication No: WO2010/064011
Pub. Date - Int. Class - Applicant: - 10.06.2010 - C09K 5/04 - INEOS FLUOR HOLDINGS LIMITED
The invention provides a heat transfer composition comprising R-1243zf, R-32 (difluoromethane) and R-161 (fluoroethane).


Title: HEAT TRANSFER COMPOSITIONS

Publication No: WO2010/064007
Pub. Date - Int. Class - Applicant: - 10.06.2010 - C09K 3/30 - INEOS FLUOR HOLDINGS LIMITED
The invention provides a heat transfer composition comprising a minimum of about 80 % by weight of R-1243zf and a maximum of 20 % by weight of R-32, based on the total weight of the composition.


Title: HEAT TRANSFER COMPOSITIONS

Publication No: WO2010/064005
Pub. Date - Int. Class - Applicant: - 10.06.2010 - C09K 5/04 - INEOS FLUOR HOLDINGS LIMITED
The invention provides a heat transfer composition comprising: (ii) R-1243zf; (iii) a second component selected from R-32 (difluoromethane), R-744 (CO)2, R- 41 (fluoromethane), R-1270 (propene), R-290 (propane), R-161 (fluoroethane) and mixtures thereof; and (iv) a third component selected from R-134a (1,1,1,2-tetrafluoroethane), R-125 (pentafluoroethane), R-1234yf (2,3,3,3-tetrafluoroprop-1-ene) and mixtures thereof.


Title: ANTIOXIDANT COMPOSITIONS FOR SOFT ORAL TISSUE AND METHODS OF FORMULATION AND USE THERE

Publication No: WO2010/062835
Pub. Date - Int. Class - Applicant: - 03.06.2010 - A61K 31/05 - PERIO SCIENCES, LLC
One embodiment of the invention is directed to an oral antioxidant composition including between 0.0001% and 5.0 % w/w antioxidant, wherein the antioxidant includes cinnamic acid derivative, tetrahydrocurcuminoids, or phloretin and an orally pharmaceutically acceptable carrier. The composition may have a pH of at least 5.0. According to still further embodiments, the composition may also include between 0.0001% and 5.0 % w/w of one or two more additional antioxidants that include cinnamic acid derivative, tetrahydrcurcuminoids, phloretin, or a stilbene derivative. In more particular embodiments, the cinnamic acid derivative may include trans-ferulic acid, the tetrahydrocurcuminoids may include tetrahydrcurcuminoids CG™, or the stilbene de...


Title: MODULATORS OF ALDEHYDE DEHYDROGENASE AND METHODS OF USE THEREOF

Publication No: WO2010/062308
Pub. Date - Int. Class - Applicant: - 03.06.2010 - A61K 31/67 - THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
The present disclosure provides compounds that function as modulators of aldehyde dehydrogenase (ALDH) enzymatic activity, as well as compositions and formulations comprising the compounds. The present disclosure provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition.


Title: METHOD AND DEVICE FOR THREE-DIMENSIONAL MEASUREMENT OF A DENTAL MODEL

Publication No: WO2010/061362
Pub. Date - Int. Class - Applicant: - 03.06.2010 - A61B 5/00 - BRAUN GMBH
The invention relates to a method for determining the cleaning performance of dental cleaning products. To do so a device for three-dimensional measurement of a dental model is provided. The device has two split-beam measuring devices (10, 10') for generating two measurement areas of the dental model. Each split-beam measuring device comprises a first (20, 20') and a second (21, 21') camera system and a beam of light (30, 30'), wherein the optical axis (25) of the lens of the first camera system is inclined by a first triangulation angle (
Title: DENTAL CARE PRODUCTS WITH DIAMOND PARTICLES

Publication No: WO2010/060653
Pub. Date - Int. Class - Applicant: - 03.06.2010 - A61Q 11/00 - AMC ABRASIVES MARKETING &CONSULTING LLP
The invention relates to a dental care product, in particular a toothpaste, comprising diamond particles. The diamond particles have sizes in a first size range from 0.3 µm to 2.5 µm, preferably from 0.5 µm to 2.0 µm, most preferably from 0.75 µm to 1.5 µm. The amount of diamond particles having sizes within the first size range is at most 2 % by weight, more preferably at most 1 % by weight, most preferably at most 0.5 % by weight of the product. Moreover, the invention relates to a kit of parts containing a toothbrush (1) and a product as above, wherein the product is a toothpaste. The bristles (2) of the toothbrush (1) may contain abrasive particles (3), such as diamond particles. The bristles (2) may also be capable of at least te...


Title: PLASMA METHOD AND APPARATUS FOR RECOVERY OF PRECIOUS METALS

Publication No: WO2010/058188
Pub. Date - Int. Class - Applicant: - 27.05.2010 - C22B 11/02 - TETRONICS LIMITED
The present invention relates to a method, and apparatus for the recovery of precious metals. Accordingly, it provides a continuous process for obtaining a precious metal composition from a feedstock material, the process comprising the steps of : (i) heating a feedstock material in a plasma furnace to form an upper slag layer and a lower molten metal layer; (ii) removing the slag layer; (iii) removing the molten metal layer; (iv) allowing the removed molten metal layer to solidify; (v) fragmenting the solidified metal layer to form fragments; and (vi) recovering a precious metal composition from the fragments; wherein the feedstock material comprises a precious metal containing material and a collector metal, said collector metal being a m...


Title: DISPENSING ASSEMBLIES, ARRAYS AND SYSTEMS FOR DENTAL ARTICLES

Publication No: WO2010/056482
Pub. Date - Int. Class - Applicant: - 20.05.2010 - A61C 19/02 - 3M INNOVATIVE PROPERTIES COMPANY
Dispensing assemblies for dental articles such as orthodontic brackets include a supply tube having a generally omega-shaped configuration. The supply tube receives a carrier strip as well as a number of containers that are releasably connected to the carrier strip. A dispenser array includes a plurality of supply tubes that are coupled to a spline by connectors. A dispensing system includes a mechanism for selectively positioning an array of supply tubes in either an upright orientation for storage or alternatively in an inclined orientation for dispensing.


Title: CONFORMING GINGIVA RETRACTION COMPRESSION CAP AND METHOD OF RETRACTING TISSUE AROUND A TOOTH

Publication No: WO2010/056301
Pub. Date - Int. Class - Applicant: - 20.05.2010 - A61C 5/14 - CENTRIX, INC.
A rolled compression cap (10) having a central bore (18). The rolled compression cap (10) has adjacent layers (12) that slide or telescope to conform to the prepared tooth (28) and to apply more direct mechanical pressure to the interface between the prepared tooth (28) and the gingiva (24). The gingiva or gum (24) retracts from the tooth (28) forming or widening a gingival sulcus (30). This improves the preparation of the tooth (28) for taking an impression and fitting a crown or cap. In one embodiment, a rolled compression cap (10) is pre-dosed or soaked with an astringent material or retraction agent. In another embodiment, the central bore (18) of the rolled compression cap (10) is filled with a paste-like or gel material (34) containin...


Title: LIQUID DROPLET INTERPROXIMAL CLEANING APPARATUS WITH GAS STREAM LIMITATION

Publication No: WO2010/055433
Pub. Date - Int. Class - Applicant: - 20.05.2010 - A61C 17/02 - KONINKLIJKE PHILIPS ELECTRONICS N.V.
The interproximal cleaning apparatus includes a gas reservoir (12) containing a compressed gas, such as CO2, in both liquid and gaseous states. A siphon tube (20) extends down into the liquid region of the gas reservoir when the apparatus is in an upright position. The siphon tube connects the reservoir to a metering valve (18) which has a metered volume to accommodate an amount of liquid compressed gas which is sufficient for good liquid droplet cleaning when it decompresses and forms a gaseous stream, without damage to the dental regions of the user. If the apparatus is severely tilted or turned upside down, gaseous CO2 or a combination of gaseous and liquid CO2 will enter the siphon tube and then the metering valve. The size of the meter...


Title: TOOTHBRUSH CONTAINING TOOTHPASTE IN AEROSOL FORM WITHIN A PRESSURISED CARTRIDGE

Publication No: WO2010/055179
Pub. Date - Int. Class - Applicant: - 20.05.2010 - A46B 11/00 - ELASTOMERIC SYSTEMS, S.L.
Toothbrush with toothpaste in aerosol form in a pressurised cartridge (4), containing multiple doses, that has a longitudinally lengthened brush (2) with a front end that is wider and has a rectangular cross section with rounded edges, on one of the larger surfaces of which are installed the bristles (8); a hollow handle (3), containing the pressurised cartridge (4), in which the back end of the brush, has fixing and binding means (13-14-32) with means of equal size and matching cavities, on the front wall of the handle; the outer surface of said handle having at least one annular rim for applying manual pressure; where the cartridge is projected towards the end of the brush, by applying manual pressure on its base, moving it a sufficient d...


Title: BIOMIMETIC ORAL CARE COMPOSITION

Publication No: WO2010/054494
Pub. Date - Int. Class - Applicant: - 20.05.2010 - A61K 8/24 - PROFIMED S.R.O.
The invention relates to an oral care composition comprising a first and a second composition wherein said first and second composition being maintained separate from each other until dispensed and combined for simultaneous application; said first composition contains a phosphate ion releaser; said second composition contains a calcium ion releaser; said first and / or said second composition contains an film forming agent; said first and / or said second composition optionally contains an acrylate polymer ion releaser; said first and / or said second composition contains a silicate ion releaser; said first and / or said second composition optionally contains abrasive particles and said first composition optionally contains an fluoride ion ...


Title: METHOD OF PRODUCING A DENTAL RESTORATION, DENTAL RESTORATION AND USE THEREOF

Publication No: WO2010/053698
Pub. Date - Int. Class - Applicant: - 14.05.2010 - A61C 13/00 - 3M INNOVATIVE PROPERTIES COMPANY
The invention relates to a method of producing a dental restoration (40), the method comprising the steps of providing a metallic frame (21) having an inner and an outer surface, applying one or more opaque layer(s) (23) or composition on the outer surface of the metallic frame, providing a facing precursor (31) having a volume A, mating the facing precursor on the outer surface of the metallic frame coated with the opaque layer using a mating composition to obtain a dental restoration intermediate, firing the dental restoration intermediate to a temperature where the facing precursor sinters to obtain a sintered facing having the volume B, and optionally applying a stain and/or glacing layer on the outer surface of the sintered facing. The...


Title: DENTAL COMPOSITION COMPRISING BIPHENYL DI(METH)ACRYLATE MONOMER COMPRISING URETHANE MOIETIES

Publication No: WO2010/048067
Pub. Date - Int. Class - Applicant: - 29.04.2010 - C08L 35/02 - 3M INNOVATIVE PROPERTIES COMPANY
Dental compositions and biphenyl di(meth)acrylate monomers are described. The dental compositions comprise at least one biphenyl di(meth)acrylate monomer comprising two aromatic rings connected with a C-C bond wherein the rings each comprise a substituent comprising a urethane moiety and a (meth)acrylate end group.


Title: LIGHT-ACTIVATED TOOTH WHITENING COMPOSITION AND METHODS THEREFOR

Publication No: WO2010/045280
Pub. Date - Int. Class - Applicant: - 22.04.2010 - A61K 8/02 - BASF CATALYSTS LLC
A method of tooth whitening using a composition that generates chlorine dioxide when exposed to electromagnetic energy is disclosed. Devices useful in the practice of the method are also provided.


Title: DENTAL COMPOSITIONS WITH FLUORESCENT PIGMENT

Publication No: WO2010/045096
Pub. Date - Int. Class - Applicant: - 22.04.2010 - A61K 6/083 - 3M INNOVATIVE PROPERTIES COMPANY
The invention features a dental composition containing a fluorescent organic pigment, e.g. a hydroxyl substituted aryl guanamine an or a fluorescent compound encapsulated in a thermo plastic or thermo set polymer, in an amount that provides the composition with fluorescence resembling that of natural teeth.


Title: NITRIC OXIDE RELEASING PARTICLES FOR ORAL CARE APPLICATIONS

Publication No: WO2010/044875
Pub. Date - Int. Class - Applicant: - 22.04.2010 - A61K 8/19 - NOVAN, INC.
The present invention provides an oral care composition comprising a nitric oxide releasing particle and an orally-acceptable carrier. The nitric oxide releasing particle comprises at least one nitric oxide donor; Another aspect of the present invention provides a device for oral care comprising a nitric oxide releasing particle, wherein the device is configured to expose a targeted site in an oral cavity of a subject to nitric oxide. The present invention also provides methods and uses of providing oral health benefits by using the oral care compositions or devices as described above.


Title: BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES

Publication No: WO2010/040188
Pub. Date - Int. Class - Applicant: - 15.04.2010 - A61K 31/19 - THE BIONIC EAR INSTITUTE
The invention relates to a biodegradable polymer comprising a plurality of releasable bioactive moieties, the releasable bioactive moieties being pendant from and covalently bonded to the biodegradable polymer backbone, wherein the biodegradable polymer backbone is formed from monomeric units that are each coupled via a biodegradable moiety, and wherein the bioactive moieties are capable of being released at a rate equal to or faster than the rate of biodegradation of the polymer backbone.


Title: POLYMER-BIOACTIVE AGENT CONJUGATES

Publication No: WO2010/040187
Pub. Date - Int. Class - Applicant: - 15.04.2010 - C08G 63/00 - THE BIONIC EAR INSTITUTE
A bioerodible polymer - bioactive agent conjugate comprising as part of its polymer backbone a moiety of general formula (I) wherein: A and B, which may be the same or different, represent the remainder of the polymer backbone and are (i) attached to the -O-R(ZD)-O- moiety as shown in formula (I) via a bioerodible moiety, and (ii) each formed from monomeric units that are coupled via a bioerodible moiety; R represents a linear or branched optionally substituted hydrocarbon; Z is a linking group; and D is a releasable bioactive agent.


Title: DENTAL APPLIANCE, PROCESS FOR PRODUCING A DENTAL APPLIANCE AND USE THEREOF

Publication No: WO2010/039910
Pub. Date - Int. Class - Applicant: - 08.04.2010 - A61C 13/00 - 3M INNOVATIVE PROPERTIES COMPANY
The invention relates to a process for producing a dental appliance, the process comprising the steps of a) providing a mixture of a liquid, an inorganic binder precursor being able to undergo a sol/gel reaction and a glass or glass ceramic powder, b) casting the mixture into a mould, c) drying the cast mixture in the mould to obtain a machinable dental appliance, d) optionally machining the dental appliance to obtain a dental workpiece, e) optionally removing the dental appliance or dental workpiece from the mould, f) optionally sintering the dental appliance or dental workpiece and to a dental appliance obtainable by such a process.


Title: PHARMACEUTICAL COMPOSITION COMPRISING COENZYME Q10

Publication No: WO2010/038239
Pub. Date - Int. Class - Applicant: - 08.04.2010 - A61K 38/43 - SHARMA, Saumya
A pharmaceutical composition for administration in gum pockets caused by periodontal disease, consisting: coenzyme Q10 and pharmaceutically acceptable excipients selected from the group comprising solubilizer; biodegradable polymer; solvent, and/or combinations thereof. A process for making a pharmaceutical composition for administration in pockets in gums caused by periodontal disease, consisting: coenzyme Q10 and pharmaceutically acceptable excipients wherein the solubilizer was dissolved in the solvent with stirring to obtain a clear solution followed by addition of the biodegradable polymer to this solution with stirring to obtain a clear solution; to this solution CoQ10 was added with vortexing to form a uniform suspension.


Title: NOVEL COMPOSITION

Publication No: WO2010/037701
Pub. Date - Int. Class - Applicant: - 08.04.2010 - A61K 8/21 - GLAXO GROUP LIMITED
A dentifrice composition comprising a source of fluoride ions and from 0.01-1.5% 5 w/w of a xanthan gum, from 0.01-1.5% w/w of a polyacrylic acid, from 0.01-2.0% w/w of a carageenan gum and a thickening silica and wherein the composition has a p H of between 5.5 and 6.5.


Title: PLASMA SPRAY PROCESS AND PRODUCTS FORMED THEREBY

Publication No: WO2010/037562
Pub. Date - Int. Class - Applicant: - 08.04.2010 - C23C 4/06 - SMITH &NEPHEW ORTHOPAEDICS AG
A plasma spray process, comprising the following steps: providing a first material; providing a second material; providing a plasma source; and introducing the first and second materials into the plasma source in order to produce a plasma spray, wherein the second material at least partially melts in the plasma and binds the first material. A composition of matter formed by such a process. A substrate modified by such a process.


Title: ACTIVE SILK MUCO-ADHESIVES, SILK ELECTROGELATION PROCESS, AND DEVICES

Publication No: WO2010/036992
Pub. Date - Int. Class - Applicant: - 01.04.2010 - A61L 27/36 - TRUSTEES OF TUFTS COLLEGE
The present invention provides for compositions, methods and devices for rapidly converting silk fibroin solution into a silk fibroin gel using direct application of voltage, in a process called electrogelation. The silk fibroin gel may be reversibly converted back to liquid form by applying reverse voltage or may be converted further to ß-sheet structure by applying shear force or other treatments. The electrogelated silk may be used as an extracted bulk gel, spray or stream of gel for processing into materials or devices, or may be used as silk gel coating to devices. Active agents may be embedded in the silk gel for a variety of medical applications. The electrogelated silk exists as a piezoelectric silk material comprising a mixture of...


Title: Reducing astringency in compositions containing phenolic compounds

Publication No: WO2010/034642
Pub. Date - Int. Class - Applicant: - 01.04.2010 - A23L 1/22 - NESTEC S.A.
The present invention in general relates to the field of taste. In particular it relates to the reduction of astringency. One embodiment of the present invention relates to the use of at least one phospholipid for the preparation of a phenol containing composition to reduce the astringency of the composition.


Title: SOLDER FORMULATION AND USE IN TISSUE WELDING

Publication No: WO2010/033765
Pub. Date - Int. Class - Applicant: - 25.03.2010 - A61L 31/04 - THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
Supersaturated gel formulations including a solution of chitosan, albumin, and a laser specific chromophore. Laser tissue welding methods using the gel formulations of the present invention are also described. In the methods, the gel formulation of the present invention is provided to a site for tissue repair and the laser specific chromophore within the gel is excited with a laser in order to fuse tissue by inducing protein denaturation. The gel formulations and laser tissue welding methods may be used, for example, to enable skull base repairs, aerodigestive endoscopic repairs, endoscopic endonasal surgical repairs, iatrogenic esophageal perforation repairs, laparoscopic abdominal surgical repairs, lung repairs, colon repairs, anastomosis...


Title: DENTAL FLOSS WITH ELLIPSOIDAL FLOSS

Publication No: WO2010/029200
Pub. Date - Int. Class - Applicant: - 18.03.2010 - A61C 15/04 - RIVAS NIETO, Joaquín Claudio
Dental floss with ellipsoidal knot, characterized in that it has ellipsoidal, fluffy, soft and rough knots incorporated sequentially along the length of such dental floss. The knots achieve notable improvement in bucco-dental cleanliness, removing food residues remaining between teeth and gums and between teeth, removing and carrying away bacterial plaque which the dental floss presently in use does not succeed in detaching. Bacteria in the plaque produce toxins which may irritate the gums, causing them to redden, swell and bleed, signs typically associated with gingivitis. With elimination of plaque we render formation of scale or tartar impossible, improving bucco-dental cleanliness and health. The objective of the present invention is to...


Title: A TOOTHBRUSH CONTAINING TOOTHPASTE

Publication No: WO2010/028457
Pub. Date - Int. Class - Applicant: - 18.03.2010 - A46B 11/04 - HINDLEY, Simon
A toothbrush containing toothpaste, the toothbrush having a body portion adapted to allow a gripping and manipulation of the toothbrush, the body portion having a reservoir for storage of toothpaste therein, a head portion with a plurality of bristles for contact with a user's teeth and an outlet co-located with the bristles, a toothpaste supply conduit associated with both the reservoir and the outlet and an actuable pump mechanism to force toothpaste from the reservoir to the head portion and out of the outlet.


Title: IMPROVED DENTAL CLEANING DEVICE

Publication No: WO2010/028383
Pub. Date - Int. Class - Applicant: - 11.03.2010 - A61C 17/22 - RYCA INTERNATIONAL, INC.
Powered toothbrush systems that provide improved bristle positioning and bristle contact with tooth surfaces that reduce the time and effort required for effective brushing. Some embodiments use alternating or oscillating pneumatic pressure and suction to move a tooth brush head. Various configuration of the brush head provide different areas of coverage ranging from individual tooth to quarter mouth (U-cross section), to half (U-cross section or H-cross section) or whole mouth (U-cross section or H-cross section) coverage. Some embodiments include flexible fingers and/or bladders to keep the bristle tips properly engaged with the teeth and gums, providing bristle contact over a wide variety of malocclusion. The shape of the brush heads ada...


Title: DENTAL COMPOSITION COMPRISING BIPHENYL DI(METH)ACRYLATE MONOMER

Publication No: WO2010/027676
Pub. Date - Int. Class - Applicant: - 11.03.2010 - A61K 6/02 - 3M INNOVATIVE PROPERTIES COMPANY
Dental compositions and methods of treating an oral surface are described. The dental compositions comprise at least one biphenyl di(meth)acrylate monomer.


Title: POLYMERIC MATERIAL

Publication No: WO2010/026433
Pub. Date - Int. Class - Applicant: - 11.03.2010 - A61L 29/08 - THE QUEEN'S UNIVERSITY OF BELFAST
There is provided a device comprising a body structure having one or more surfaces wherein at least one of the surfaces comprises a pH sensitive layer comprising a linear polymer, wherein the water solubility of the linear polymer increases from a first water solubility to a second water solubility at a pH trigger. A method of forming a device, and a method of preventing or mitigating infection is also described.


Title: ORAL CARE DEVICE WITH A FUNCTION ELEMENT

Publication No: WO2010/023643
Pub. Date - Int. Class - Applicant: - 04.03.2010 - A61C 17/22 - BRAUN GMBH
The invention is directed to an oral care device having a handle and a head connected or connectible thereto, on which oral care elements, in particular cleaning bristles and/or elastomer cleaning elements are provided, with an electrically operable function element being arranged on an outer surface of the head. To ensure ease of handling of the oral care device in spite of the function element accommodated in the head, it is proposed providing a ramp adjacent to the function element.


Title: TOOTHBRUSH WITH CONTAINER FOR TOOTHPASTES AND THE MECHANISM FOR DOSAGE

Publication No: WO2010/023493
Pub. Date - Int. Class - Applicant: - 04.03.2010 - A46B 11/00 - STUBLIN, Vedran
Toothbrush with the toothpaste container and a mechanism for dosage which includes a toothbrush handle 1, neck toothbrush 4 and toothbrush head 3 with the elements of storage and dosing toothpastes, and elements for the implementation of toothpaste from the toothpaste container to the space between the threads for brushing that are located on the toothbrush head 3. Toothbrush head is performed in a way that has opened for output toothpastes 17 in the space between the threads for brushing and a channel for conducting toothpastel5 to the opening of the exit 17. Toothbrush neck was made in a way that includes a channel for the implementation of toothpaste 15 from the toothpaste container 14 to the toothbrush head. Toothbrush handle is perform...


Title: METHOD AND TRANSFER ELEMENT FOR MANUFACTURING A SUPERSTRUCTURE AND A CORRESPONDING TEMPLATE

Publication No: WO2010/022479
Pub. Date - Int. Class - Applicant: - 04.03.2010 - A61C 1/08 - DE CLERCK, René
Method for manufacturing an aligning plate (3) with at least one opening (4) designed for drilling a bore hole (5) in a specific place in the bone of a lower or upper jaw (1) through said opening (4) to thus fix an implant (9,10) in the bore hole (5) in said bone in an oral cavity, whereby the position of said opening (4) in the aligning plate (3) and the position of the latter in the oral cavity are determined in relation to at least one reference organ (2) that is fixed to a tooth (12) situated in said lower or upper jaw (1).


Title: INDUCTIVE POWER TRANSFER SYSTEM FOR PALATAL IMPLANT

Publication No: WO2010/019805
Pub. Date - Int. Class - Applicant: - 18.02.2010 - A61F 5/56 - PAVAD MEDICAL, INC.
An inductive power transfer system associated with an airway implant device (8) is disclosed. A non-implanted portion of the system comprises a mouthpiece or retainer. The mouthpiece includes a power transfer circuit and a power source (4). The power transfer circuit includes a receive circuit configured to receive a first inductive power transfer from a charging device and to deliver a charging current to the power source. The power transfer circuit also includes a transmit circuit coupled to the power source. The transmit circuit is configured to provide a second inductive power transfer from the mouthpiece to the airway implant. Some embodiments of the non-implanted portion include a charge controller and a lithium polymer battery. Some ...


Title: ANTIMICROBIAL GEL FORMULATIONS

Publication No: WO2010/019723
Pub. Date - Int. Class - Applicant: - 18.02.2010 - A01K 9/00 - NOVABAY PHARMACEUTICALS, INC.
Disclosed herein are formulations comprising an N-halogenated or N,N- dihalogenated amine compound dispersed in a water-swellable polymer, wherein the compound is 90% stable for at least 30 days at about 25 °C. Also disclosed are methods of treating or preventing infections caused by a bacterial, a microbial, a sporal, a fungal or a viral activity using such formulations.


Title: BRIDGED POLYCYCLIC COMPOUND BASED COMPOSITIONS FOR TOPICAL AND ORAL APPLICATIONS

Publication No: WO2010/019611
Pub. Date - Int. Class - Applicant: - 18.02.2010 - C07D 259/00 - ALLACCEM, INCORPORATED
A pharmaceutically active agent, a pharmaceutically active agent carrier and method of use thereof are described. In some embodiments, a system may include a composition. The composition may include one or more bridged polycyclic compounds. At least one of the bridged polycyclic compounds may include at least two cyclic groups, and at least two pharmaceutically active agents may be associated with the bridged polycyclic compound. In some embodiments, one or more bridged polycyclic compounds may be applied to an oral surface, topical surface, and/or an otic surface of an animal (e.g., canine, feline) or a human such that an associated malady may be inhibited and/or ameliorated.


Title: ORAL CARE COMPOSITION COMPRISING CAPSULES

Publication No: WO2010/019587
Pub. Date - Int. Class - Applicant: - 18.02.2010 - A61K 8/11 - COLGATE-PALMOLIVE COMPANY
Oral care compositions comprising a capsules comprising flavoring and/or one or more active ingredients, and/or flavours, said capsules distributed in an orally acceptable vehicle or carrier.


Title: A UNIVERSAL TEMPLATE ENABLING DRILLING AND PLACING A DENTAL IMPLANT INTO A PATIENT'S JAW

Publication No: WO2010/018565
Pub. Date - Int. Class - Applicant: - 18.02.2010 - A61C 1/08 - NAHMANI, Mordhay
An apparatus for drilling into a patient's jaw, the apparatus comprising: a gel template; a cylinder embedded in the gel template; and a support arranged to fixate the gel template and the therein embedded cylinder in respect to the jaw, wherein the gel template comprises a gel selected to harden responsive of electromagnetic radiation, wherein the cylinder is arranged to allow drilling into the jaw, and wherein the cylinder is positioned within the gel template such as to enable drilling into the jaw through the cylinder.


Title: Multiphase liquid composition for low voltage electrowetting device

Publication No: WO2010/015691
Pub. Date - Int. Class - Applicant: - 11.02.2010 - C11D 1/66 - VARIOPTIC
A multi-phase liquid composition comprising a conductive liquid and a non-conductive liquid, said liquids being non miscible, wherein the conductive liquid comprises more than 90% up to 99.9% by weight of a first component having a surface tension above 45 mN/m and comprising water, salt and at least one freezing point lowering agent, and from 0.01% to less than 10% by weight of a second component having a surface tension below 30 mN/m and comprising at least one first compound, wherein said at least one first compound is a non ionic surfactant.


Title: A PREPARATION FOR BEING FASTENED ON A NATURAL TOOTH PART OR TOOTH AND METHOD OF MANUFACTURING SUCH A PREPARATION

Publication No: WO2010/009567
Pub. Date - Int. Class - Applicant: - 28.01.2010 - A61K 6/08 - WOODWELDING AG
According to different aspects of the invention, a dental preparation is manufactured and provided, the dental preparation for being fixed on a natural tooth part or tooth, in particular for replacement of a load-bearing tooth part, said preparation being positionable in the natural tooth part or on the natural tooth part or tooth and comprising at least one region or one part of a material with thermoplastic properties, the at least one region forming at least part of the preparation surface, wherein the at least one part of a material with thermoplastic properties comprises a thermoplastic polymer forming a polymer matrix, and further comprising a plurality of filler elements (such as filler particles or fibers etc.) of a material that is...


Title: DENTAL HYGIENE TOOL

Publication No: WO2010/009373
Pub. Date - Int. Class - Applicant: - 21.01.2010 - A61C 15/00 - ELBAZ, Jean-jacques
A dental hygiene tool (110) particularly adapted for cleaning and treating dental spaces, surfaces and other areas including interproximal surfaces, orthodontic appliances, bridgework, crowns, surgical sites, implants and periodontal pockets and for gently massaging and compressing gingival tissues and to help reduce inflamation and pocket depth, in a single device. The tool comprises a conical, hollow, compressible and expansive tip (113) made of elastomeric material and having a pointed end (125) dimensioned to penetrate interproximal spaces. Rows of pointed spicules (114) of the same material project radially from the outer surface (123) of the tip in progressively diminishing sizes from the base of the conical tip to its apex. The tip i...


Title: TOOTH WHITENING COMPOSITIONS AND METHODS

Publication No: WO2010/009192
Pub. Date - Int. Class - Applicant: - 21.01.2010 - A61K 8/20 - BASF CATALYSTS LLC
A non-cytotoxic chlorine dioxide composition and a mixed agent bleaching composition for tooth whitening are disclosed. Methods of use are also provided.


Title: PHARMACEUTICAL COMPOSITION COMPRISING JASMONATES

Publication No: WO2010/006392
Pub. Date - Int. Class - Applicant: - 21.01.2010 - A61K 31/122 - FEHR PEREIRA LOPES, José. E.
The present invention refers to pharmaceutical compositions comprising a jasmonic acid derivative and a carrier, preferably cyclodextrin or a polyamidoamine). Said compositions may be used for treating cancer.


Title: FUNCTIONAL MICELLES FOR HARD TISSUE TARGETED DELIVERY OF CHEMICALS

Publication No: WO2010/006192
Pub. Date - Int. Class - Applicant: - 14.01.2010 - A61K 31/66 - BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
Compositions and methods for targeting agents to hard tissue are provided comprising. A method includes administering to a subject a composition comppsing micelles, the micelles comppsing at least one amphiphilic block copolymer linked to at least one tooth targeting moiety. The composition further includes at least one encapsulated compound and is provided in a pharmaceutically acceptable carrier.


Title: COMPOSITION FOR ENHANCING BIOSYNTHESIS OF HYALURONIC ACID OR GLYCOSAMINOGLYCAN COMPRISING OROTIC ACID, A SALT THEREOF, OR A DERIVATIVE THEREOF

Publication No: WO2010/005123
Pub. Date - Int. Class - Applicant: - 14.01.2010 - A61K 38/14 - MAZENCE INC.
The present invention relates to a composition for enhancing biosynthesis of hyaluronic acid or glycosaminoglycan comprising orotic acid, a salt thereof, or a derivative thereof. The composition comprising orotic acid, a salt thereof, or a derivative thereof according to the present invention can be used for preventing, treating or improving arthritis, disk, skin aging, wrinkle, scheroma, ophthalmic diseases, wound, scar, colpoxerosis, gum diseases, interstitial cystitis, atopic dermatitis or xeroderma, etc. which can be caused by decline of production and hypofunction of hyaluronic acid or glycosaminoglycan.


Title: NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

Publication No: WO2010/002209
Pub. Date - Int. Class - Applicant: - 07.01.2010 - C07D 307/14 - AMOREPACIFIC CORPORATION
This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, heart disease and so on..
World  Patents Published  in 2011
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WORLD PATENTS IN ORAL CARE FORMULATIONS PUBLISHED IN 2010
This list includes patent documents published by the World Intellectual Property Organization (WIPO). The list was retrieved by using a refined search strategy in the claims section of all
patent applications. Salient search terms included oral care formulations and compositions for tooth cleaning and whitening; denture and dental prosthesis care; caries, calculus, stains
and plaque prevention, reduction or removal; dental adhesives, dental polymers, cement curing; polymer UV curing, cavity fillers, disinfectants, bleaching; oral hygiene and devices, etc.
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