PCT - World Oral Care Formulation Patents Published
from 1990 to 2006

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PCT - WORLD PATENTS IN ORAL CARE PUBLISHED FROM 1990 TO 2008


METHOD FOR CONTROL OF DRUG ELUTION RATE AND COMPOSITION FOR COATING OF DRUG-ELUTING STENT

(WO2006137222) 28.12.2006 A61L 31/00 Tokyo Medical and Dental University
Disclosed are a method for controlling the elution of a drug from a stent and a drug-eluting stent capable of reducing the restenosis rate after therapy. A coating composition for a drug-eluting stent comprising an endothelin receptor antagonist and a copolymer of 2-methacryloyloxyethyl phosphorylcholine and n-butyl methacrylate. The elution of the endothelin receptor antagonist from the coating composition can be controlled by varying the ratio of 2-methacryloyloxyethyl phosphorylcholine to n-butyl methacrylate in the copolymer.
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DISPOSABLE TOOTH BRUSH

(WO2006137104) 28.12.2006 A46B 5/04 VUOCOLO, Beniamino
Object of the present invention is a disposable tooth brush for the oral hygiene. It is made up of a thimble consisting of a thin and elastic tubular membrane made of natural and synthetic latex, which can be rolled up and down over a finger and, on its front, corresponding to its closed end or on circular parts of the thimble surface, it is provided with a cleaning part having bristles or barbels on which a substance made of tooth dust or paste or gel is added, or sprinkled or soaked in it.
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COMPOSITION FOR THE MINERALIZATION OF DENTAL HARD TISSUES AND THE REDUCTION OF CARIES-INDUCIVE MICROFLORA

(WO2006135601) 21.12.2006 A61Q 11/00 PELDYAK, John
The present invention relates to a composition having increased levels of minerals for mineralizing hard tissues within the oral cavity and an ability to reduce caries-inducive microflora. The composition also has, among other things, an anti-dental caries function that promotes beneficial oral health.
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A CARTRIDGE FOR AN APPLIANCE FOR PERSONAL CARE AND AN APPLIANCE COMPRISING SUCH A CARTRIDGE

(WO2006134514) 21.12.2006 A45D 27/00 KONINKLIJKE PHILIPS ELECTRONICS N.V.
A cartridge for an appliance for personal care, such as skin, dental or hair treatment includes a main body (2), a dispensing structure (3, 11, 12) for dispensing a substance, such as a liquid, a paste or a gel, and a cartridge (3) detachably connected to the main body (2). The cartridge bounds a reservoir space (5) for holding the substance to be dispensed and includes: a flexible wall part (7) bounding the reservoir space (5) for allowing reservoir space (5) volume to accommodate to a volume of the substance filled therein and volumes of the substance dispensed therefrom; a rigid wall part (16) also bounding the reservoir space (5), and a rigid housing (6, 14). The flexible wall part (7) is connected to the rigid housing (6, 14) along a c...
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THERMOCHROMIC MATERIAL FOR DENTAL IMPRESSION AND METHOD

(WO2006134437) 21.12.2006 A61K 6/10 ZHERMACK S.P.A.
The present invention relates to a thermochromic material for dental impression, capable of reversibly changing colour depending on the temperature at which said material is found, a method for its preparation and the use thereof. Said material includes a bicomponent silicone composition in combination with at least a thermochromic pigment.
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APPLICATOR FOR A FLUID COMPOSITION

(WO2006133862) 21.12.2006 A61C 5/06 DENTSPLY DETREY GMBH
A disposable applicator () for a unit dose of a fluid dental composition (30), which comprises (a) a rigid elongated member (10) having a proximal end (101) and a distal end (102), (b) a flexible film (20) provided on a lateral surface of the rigid elongated member (10), said film defining walls of a storage compartment (201), and (c) a fluid composition (30) contained in the storage compartment (201).
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THERAPEUTIC AGENT FOR NEUROGENIC PAIN

(WO2006132432) 14.12.2006 A61K 45/00 JAPAN SCIENCE AND TECHNOLOGY AGENCY
Disclosed is a therapeutic agent for neurogenic pain which has an excellent therapeutic effect on neurogenic pain which is an intractable disease. More specifically, disclosed are: a therapeutic agent for neurogenic pain comprising a casein kinase 1 inhibitor (particularly N-(2-aminoethyl)-5-chloro-isoquinoline-8-sulfonamide or the like) as an active ingredient; a pharmaceutical composition for treatment of neurogenic pain comprising a casein kinase 1 inhibitor as an active ingredient; a method for treatment of neurogenic pain using a casein kinase 1 inhibitor; and others.
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PROCESS FOR PREPARATION OF GRANULAR ORAL COMPOSITION USING OLIGOSACCHARIDE SOLUTION

(WO2006129468) 07.12.2006 A61K 9/16 SUNTORY LIMITED
Disclosed is a granular oral composition which can be shaped (granulated) by using a solution of an oligosaccharide as a binder without the need of using any binder other than the oligosaccharide in the shaping (granulation) of a powdery material for oral use and which shows a good feeling in the mouth when suspended and unsuspended in a liquid. An oligosaccharide is dissolved in a spray solution to be used in the flow bed granulation method and the resulting solution is sprayed onto a powdery material for oral use, whereby the material for oral use can be granulated using the oligosaccharide as a binder.
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COMPOSITION FOR TREATING PERIODONTAL DISEASE

(WO2006129393) 07.12.2006 C07K 14/47 JAPAN SCIENCE AND TECHNOLOGY AGENCY
To provide a composition for treating periodontal disease, a method of developing periodontal ligament, and a polypeptide, a polynucleotide, a recombinant expression vector and a transformant to be used therefor, it was identified that human ADAMTSL4a protein, human ADAMTSL4 protein, mouse ADAMTSL4a protein and mouse ADAMTSL4 protein are factors regulating a periodontal ligament regeneration process. Periodontal ligament can be developed using a composition containing any of these proteins, a composition containing a transformant into which a gene encoding any of these proteins has been introduced, a recombinant expression vector containing a gene encoding any of these proteins. As a result, a tissue destroyed by periodont...
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DENTAL COMPOSITION FOR DETECTION OF CARIOUS TISSUE, DETECTION METHOD

(WO2006125650) 30.11.2006 A61K 8/40 3M ESPE AG
The present invention relates to a dental composition comprising an aqueous Solution of 1 ) at least one acidic Compound, 2) at least one salt of said acidic Compound, 3) at least one indicator that generates a detectable Signal when said Solution reaches a particular pH value that is less than 5.5 wherein 1 ) and 2) are selected such that the aqueous Solution has a pH of less than that particular pH value where the indicator generates the Signal. It further relates to a method for detection of carious tissue on the surface of a tooth, comprising the Steps of 1 ) providing the above mentioned dental composition, 2) applying said composition to the surface of said tooth, and 3) measuring the amount of time required for the composition to cha...
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INDUSTRIAL TUNNEL TYPE WOOD BURNING OVEN FOR THE BAKING OF PIZZA AND SIMILAR ALIMENTARY PRODUCTS

(WO2006125475) 30.11.2006 A21B 1/48 TECNOFORNI S.R.L.
An industrial oven with tunnel for the baking of pizza or similar alimentary products is shown, made up of a bearing structure (10) in refractory material comprising an inlet mouth (40) and one of outlet (41) connected by a passing through tunnel (4) along which a baking surface (5) supporting pizza or similar alimentary products slides. Said oven is heated with firewood and it comprises slits (22, 24) for the passage of primary air for the combustion of the firewood and air for the oxidation of the excess smoke, said primary and secondary air being moved by fans (50) controlled by a control unit which processes data on the composition of the air detected inside the oven by sensors (26), a top combustion chamber (15) housing top furnaces (1...
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A CAN BOX WITH BUILT-IN USING TOOLS IN THE CAN BODY

(WO2006125363) 30.11.2006 B65D 77/30 LIANG, LingBo
The invention discloses a can box with built-in using tools in the can body, characterized by that the can body is provided with a support for a knife, a fork or a spoon at a portion of the can mouth inner edge. The support has at least one securing strip on its upper-surface or undersurface, and the can mouth is at its side connected to a can cover by means of a hinge. The invention has a reasonable structure and an exquisite design, it is very convenient to use. A knife, a fork or a spoon or combination of them can be placed therein according to the kind of contained material, the excrescent material can be scraped off by the edge of the support and fall into the can box. The can box according to the invention can be superposed each anoth...
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PERSONAL DENTAL CARE UNIT

(WO2006124284) 23.11.2006 B65D 35/24 CROSBY, Maxine
The personal dental care unit (10) stores most articles used in personal dental care. The device (10) attaches to a wall and includes a mechanism for attaching a tube of toothpaste (T) within the unit and dispensing the toothpaste (T) efficiently. Opposed rollers squeeze toothpaste from the tube (T) as a screw assembly advances the rollers along the tube (T). A support bracket supports the tube (T) and may be adjusted to accommodate different tube sizes. The tube (T) and mechanism (10) are enclosed in a cover (14), which includes a rack (28a, 28b) for holding toothbrushes (B2, B3, B4) and a receptacle (30) for holding a small packet of dental floss (F). The cover (14) may be provided with any form of complementary or contrasting dco...
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DENTAL ENAMEL RECALCIFICATION ACCELERATOR AND CONTAINING THE SAME, ORAL COMPOSITION AND FOOD OR BEVERAGE

(WO2006123430) 23.11.2006 A23L 2/38 LOTTE CO., LTD.
A dental enamel recalcification accelerator that even when used in oral compositions and food or beverage, poses no safety problem, and that is capable of effectively promoting the recalcification of decalcified dental enamel to thereby positively suppress any dental caries; and containing the same, an oral composition and food or beverage. There is provided a dental enamel recalcification accelerator comprising anhydrogalactose-containing red algae and/or an extract thereof as an active ingredient. Further, there are provided an oral composition and food or beverage comprising the dental enamel recalcification accelerator.
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CONFECTIONERY PRODUCTS FOR THE TREATMENT OF DRY MOUTH

(WO2006123238) 23.11.2006 A61P 1/02 MCNEIL-PPC, INC.
The present invention relates to orally ingestible compositions also referred to herein as confectionery products for delivery of saliva stimulating and/or saliva substitute to the mouth and throat. The orally ingestible compositions include a core and a shell surrounding the core so that the core is generally centrally or substantially centrally positioned therein. The composition of the core and shell make the confection uniquely suited for the targeted delivery of the saliva stimulating or saliva substitute to the mouth and throat.
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IMPROVEMENTS IN OR RELATING TO CONTAINERS FOR COOKING FOODSTUFFS

(WO2006123087) 23.11.2006 B65D 81/34 STEAMFAST EUROPE LIMITED
A pouch or bag (1) flexible plastics material for enabling food to be cooked therein under pressure having an access opening or mouth closable by means of releasable sealing or closure means in the form of a press-fit bead-and-groove or rib-and-channel closure means (4,5) wherein the projection portion is on a first strip of plastics material secured along its length to an inner surface of one side of the bag wall (2a, 2b) , and the groove or channel forming portion is formed on a second strip of plastics material secured along its length to an inner surface of a second and opposite side of a bag wall (2a, 2b) , one strip portion being secured so as to leave a freely extending flap portion (6) carrying the bead or the groove presenting when...
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AQUEOUS DISPERSIONS OF WATER-SOLUBLE AND/OR WATER-SWELLABLE ANIONIC POLYMERS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF

(WO2006122947) 23.11.2006 C08L 33/02 BASF AKTIENGESELLSCHAFT
The invention relates to aqueous dispersions of water-soluble and/or water-swellable anionic polymers, obtained by radical polymerisation of ethylenically-unsaturated anionic monomers in an aqueous medium in the presence of at least one stabilizer, whereby the polymerisation is carried out in the presence of at least one water-soluble polymer of the groups constituted by (a) graft polymers of vinyl acetate and/or vinyl propionate on (i) polyethylene glycols or (ii) polyethylene glycols or polypropylene glycols, the end groups of which are singly or doubly terminated by alkyl, carboxyl or amino groups, polyalkylene glycols, polyalkylene glycols, the end groups of which are singly or doubly terminated by alkyl, carboxyl or amino groups and (b...
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DENTAL COMPOSITIONS CONTAINING HYBRID MONOMERS

(WO2006122081) 16.11.2006 A61K 6/083 3M INNOVATIVE PROPERTIES COMPANY
The invention features dental compositions comprising at least one hybrid monomer that comprises a cyclic allylic sulfide moiety attached to a (meth)acryloyl moiety. These two functional moieties are typically joined either directly to each via a chemical bond or through some chemical structure or spacer molecule. The composition may optionally contain additional polymerizable compounds, such as ethylenically unsaturated compounds, that are typically used in dental compositions.
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HARDENABLE DENTAL COMPOSITIONS WITH LOW POLYMERIZATION SHRINKAGE

(WO2006122074) 16.11.2006 A61K 6/083 3M INNOVATIVE PROPERTIES COMPANY
The present invention features a hardenable dental composition that contains: (1) at least one cyclic allylic compound having at least one sulfur atom in the ring, and (2) at least one at least one ethylenically unsaturated compound, such as a substituted (meth)acryloyl compound. The compositions also typically comprise an initiator system, preferably a photoinitator system containing at least 0.08 wt-% of one or more photosensitizers.
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ANTISENSE ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING FOOT AND MOUTH DISEASE

(WO2006121951) 16.11.2006 A61K 48/00 AVI BIOPHARMA, INC.
An antiviral antisense composition and method for treating foot-and-mouth disease virus (FMDV) in veterinary animals is disclosed. The composition contains an antisense compound that has a sequence effective to target at least 12 contiguous bases of an FMDV RNA sequence within a region of the positive-strand genomic RNA defined by SEQ ID NO:25, and preferably, one of the viral sequences within SEQ ID NO:25 identified by SEQ ID NOS: 26-28. The composition is administered in a therapeutically effective amount in treating FMDV.
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CONTAINER CLEANING DEVICE, CONTAINER CLEANING METHOD, AND TANK

(WO2006120873) 16.11.2006 B08B 9/20 TOYOTA JIDOSHA KABUSHIKI KAISHA
A cleaning device (30) and a cleaning method for a container (1) and a tank capable of continuously performing washing treatment. The cleaning device (30) comprises jetting bodies (32, 34, 36) jetting a fluid inside the container (1), a moving device (38) moving the jetting bodies (32, 34, 36) relative to the container (1) along the axis of the container (1) so that the jetting bodies (32, 34, 36) can be inserted from the mouth part of the container to the inside of the container (1), and a switching device (40) switching the jetting bodies (32, 34, 36) from one function to the other functions. The switching device (40) selects the nozzle (32) for cleaning fluid, the nozzle (34) for blowing off water, and the nozzle (36) for drying in this ...
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ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES

(WO2006120135) 16.11.2006 A01N 59/16 CIBA SPECIALTY CHEMICALS HOLDING INC.
The present invention relates to antimicrobial, porous particles, especially porous, non- platelet-like SiO2 particles, comprising an organic, or inorganic antimicrobial compound, or composition, with the proviso that the porous particles are not porous SiOz flakes, wherein 0.70 < z < 2.0, especially 0.95 < z < 2.0, which provide enhanced (long term) antimicrobial efficacy.
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ORAL HYGIENE DEVICES EMPLOYING AN ACOUSTIC WAVEGUIDE

(WO2006119376) 09.11.2006 A47L 1/00 ULTREO, INC.
An oral hygiene device having an ultrasound transducer 22 and an acoustic waveguide 24 facilitating the transmission of ultrasonic acoustic energy to fluids in the oral cavity is disclosed. Preferred ultrasound operating parameters for operation in aqueous environments and in dental slurries are disclosed. Devices may incorporate a drive motor 16 for oscillating a device head 23, acoustic waveguide 24 and one or more bristle tuft(s) 26 at sonic frequencies, and preferred sonic operating parameters are also provided. Multi-element piezoelectric transducer assemblies 30, 40, and various control and communications features are disclosed. Oral hygiene devices disclosed herein achieve improved plaque and stain removal from the teeth as well as i...
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CHILDREN'S COMBINATION TOOTHBRUSH AND TOOTHPASTE DISPENSER, AND METHOD

(WO2006119194) 09.11.2006 A47K 5/18 THE PROCTER &GAMBLE COMPANY
A combination toothbrush and toothpaste dispenser, and method, are adapted for use by a child. The dispenser provides an easily actuatable activator that, when operated, discharges a predetermined amount of toothpaste from an orifice. The toothbrush is adapted to automatically lift the toothbrush head off of a support surface to a height near that of the dispenser orifice. As a result, a child may focus on manipulating one item at a time when loading a toothbrush with toothpaste.
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MALLEABLE SYMMETRIC DENTAL CROWNS

(WO2006119003) 09.11.2006 A61C 13/087 3M INNOVATIVE PROPERTIES COMPANY
Preformed malleable dental crowns with a side-generic external shape with a plane of symmetry in the facial-lingual direction and/or a plane of symmetry in the mesial-distal direction. The preformed dental crowns also include a hardenable composition that has sufficient malleability such that the side-generic external shape can be formed into, e.g., a left-side specific or right-side specific adjusted external shape. Methods of the invention may include fitting the dental crowns by adjusting or forming them to provide side-specific features, followed by hardening of the hardenable composition.
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EXOSKELETON SUPPORT FOR PLACEMENT OF A DENTAL TREATMENT STRIP

(WO2006118834) 09.11.2006 A61C 5/00 ULTRADENT PRODUCTS, INC.
An exoskeleton support (114) and associated placement system (100) for use in placing a thin, flexible dental treatment strip (104) over a person's tooth surfaces. The exoskeleton support (114) includes an exoskeleton body (102) that is curved so as to approximate the curvature of a person's dental arch. The exoskeleton support (114) includes an inner surface (108) that is oriented toward a person's tooth surfaces during use, an outer surface (110) oriented away from the person's tooth surfaces during use, and adhesive material (112) for temporarily holding or attaching a flexible dental treatment strip (104) to the inner surface (108) of the exoskeleton support (114). The exoskeleton support (114) allows a user to more easily and accuratel...
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DENTAL FLOSS COMPOSITIONS COMPRISING MENTHOL AND CARBOXAMIDES

(WO2006116436) 02.11.2006 A61C 15/04 THE PROCTER &GAMBLE COMPANY
The present invention relates to a dental floss or dental article comprising: a. a monofilament substrate; b. a coating composition coated on the monofilament substrate comprising a mixture of menthol and a coolant selected from the group consisting of N-substituted-p-menthane-carboxamides, acyclic carboxamides, and mixtures thereof; wherein the ratio of the coolant to menthol is from about 1:1 to about 2.5:1.
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COMPUTER AIDED ORTHODONTIC TREATMENT PLANNING

(WO2006115841) 02.11.2006 G06T 15/00 ALIGN TECHNOLOGY, INC.
Methods, devices and systems for digitizing a patient's arch and manipulating the digital dental arch model. In one variation the methods includes producing a physical arch model for the patient's arch, separating the physical arch model into a plurality of arch model components, mounting the arch model components on a scan plate, capturing one or more images of the arch model components, and developing digital representations of the arch model components using the captured one or more images.
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AGENT FOR TREATING NEUROPATHIC PAIN

(WO2006115304) 02.11.2006 A61K 45/00 JAPAN SCIENCE AND TECHNOLOGY AGENCY
It is intended to provide an agent for treating neuropathic pain which has an excellent therapeutic effect on neuropathic pain, which is an intractable disease. More particularly, it is intended to provide an agent for treating neuropathic pain containing a medicament having a glucocorticoid receptor-specific antagonism (particularly dexamethasone 21-mesylate) as an active ingredient, a pharmaceutical composition for treating neuropathic pain, a method of treating neuropathic pain using such a compound and the like.
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THERAPEUTIC AGENT FOR NEUROPATHIC PAIN

(WO2006115302) 02.11.2006 A61K 45/00 JAPAN SCIENCE AND TECHNOLOGY AGENCY
Disclosed is a therapeutic agent for neuropathic pain having an excellent therapeutic effect on neuropathic pain which is a intractable disease. More specifically, disclosed are a therapeutic agent for neuropathic pain which comprises a peripheral benzodiazepine receptor antagonist (particularly PK 11195) as the active ingredient; a pharmaceutical composition for the treatment of neuropathic pain which comprises a peripheral benzodiazepine receptor antagonist as the active ingredient; a method for the treatment of neuropathic pain using a peripheral benzodiazepine receptor antagonist; and others.
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ADHESIVE COMPOSITION

(WO2006115065) 02.11.2006 C09J 4/02 KURARAY MEDICAL INC.
An adhesive composition comprising a polymerizable monomer (a) containing a phosphoric acid group and further containing a fluorocarbon group and a solvent (b), the polymerizable monomer (a) represented by the formula: wherein R is a hydrogen atom or methyl; and each of n, p and q is a natural number and satisfies the relationships 2=n=10, p+q = n and p+q+n = 13. This adhesive composition realizes excellent adhesion force and bond durability enabling suitable application to fields, such as those of medical treatment, electronic industry, precision machinery industry and jewelry industry, and is one exhibiting a low fluctuation of adhesion force. As the adhesive composition exhibits excellent bond durability and discoloration res...
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ANTI-HEPATITIS C VIRUS AGENT CONTAINING BMP-7

(WO2006112441) 26.10.2006 A61K 38/00 TOKYO MEDICAL AND DENTAL UNIVERSITY
A pharmaceutical composition, which contains a bone morphogenetic factor (bone morphogenetic protein 7: BMP-7) as an active ingredient, suppresses the proliferation of HCV and is for the prevention or treatment of viremia caused by HCV infection is disclosed. The pharmaceutical composition of the invention is particularly useful for the prevention or treatment of a liver disease caused by HCV infection. The pharmaceutical composition of the invention containing BMP-7 as an active ingredient may be administered alone or concomitantly with a preparation containing interferon (IFN) as an active ingredient or a preparation containing ribavirin as an active ingredient.
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SHEET FOR DENTURE STABILIZATION AND POWDER COMPOSITION THEREFOR

(WO2006112123) 26.10.2006 A61C 13/23 KOBAYASHI PHARMACEUTICAL CO., LTD.
[MEANS FOR SOLVING PROBLEMS] To provide a powder composition for denture stabilization which is to be held between a pair of fabrics having a shape conforming to the shape of a denture base and comprises sodium alginate a 1 wt.% aqueous solution of which has a viscosity at 20C of 320-380 mPas and sodium alginate a 1 wt.% aqueous solution of which has a viscosity at 20C of 950-1,100 mPas in a weight proportion of from 0:1 to 1:1, preferably from 1:4 to 1:1. Weight proportions outside the range of from 0:1 to 1:1 result in a poor balance between adhesion strength and slip resistance and cannot give a denture stabilization sheet combining high adhesion strength with high slip resistance. [EFFECT] The sheet for denture...
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ORAL HYGIENE COMPOSITIONS

(WO2006111761) 26.10.2006 A61K 8/25 PSIMEDICA LIMITED
Oral hygiene compositions suitable for use as dentifrice compositions comprising a silicon abrasive agent are provided.
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ANTI-IRRITATING COUGH MIXTURE CONTAINING EXTRACTS FROM ISLAND MOSS AND MALLOW

(WO2006111258) 26.10.2006 A61K 9/08 MARIA CLEMENTINE MARTIN KLOSTERFRAU VERTRIEBSGESELLSCHAFT MBH
The aim of the invention relates to a pharmaceutical preparation which is in the form of a liquid, in particular for use as an anti-irritating cough mixture. Said pharmaceutical preparation contains a combination of island moss and mallow, optionally with at least one zinc compound, in particular at least one zinc salt, and a pharmacologically acceptable support. According to the invention, the pharmaceutical preparation can be used for the prophylactic and/or therapeutic treatment of various diseases, in particular coughs and cough irritations, in particular dry cough irritations, mucous membrane irritations and mucus membrane lesions in the mouth and pharyngeal cavity, drying of the mucous membrane in the region of the mouth and pharyngea...
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DENTAL FORMULATION

(WO2006110183) 19.10.2006 A61K 8/66 DENTAL CREATIONS LLC
An orally absorbable improved dental formulation is provided. The detal formulation, which reduce the ocurrence of oral plaque, reduce gingival inflammation and bleeding, and whiten the users teeth, may be a toothpaste or a rinse which comprises the following active ingredients: carbamide peroxide, xylitol, and coenzyme Q10 (ubiquinone).
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COMPOSITION TO BE USED FOR THE TREATMENT OF PARODONTAL PATHOLOGIES

(WO2006109344) 19.10.2006 A61K 35/64 GASPARINI, Gianluigi
A composition to be used for the treatment and the prevention of parodontal pathologies which is prepared by micro-encapsulation of slow release capsules.
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HOT FLAVOUR AND SKIN SENSATION COMPOSITION

(WO2006109241) 19.10.2006 A23L 1/221 FIRMENICH SA
The present invention relates to a flavour and skin sensation composition providing a hot or warming sensation upon consumption or application, respectively. The composition comprises a hot, warming component, a cooling component and a bitter component. In an embodiment, the composition further comprises an acid component. The composition provides a clean hot taste free of oily or earthy off-notes. Consumers prefer the composition over hot, warming compositions comprising essentially natural extracts.
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PERFUME COMPOSITIONS

(WO2006109078) 19.10.2006 C11B 9/00 QUEST INTERNATIONAL SERVICES B.V.
Perfume ingredients have been investigated and classified for their effectiveness in detaching biofilms from surfaces. Based on this classification, perfume compositions that are effective in assisting biofilm detachment can be formulated, whilst also allowing a degree of freedom in formulation that permits consideration of the hedonic properties of the composition. The compositions can be used in a wide range of perfumed consumer products, such as personal, domestic and industrial products, e.g. hard surface cleaning products, dental care products, and deodorant products.
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FOAM STRIP FOR THE DELIVERY OF ORAL CARE COMPOSITIONS

(WO2006108432) 19.10.2006 A61Q 11/00 REMEDENT NV
The present invention relates to a polyurethane foam strip (1), shaped for the application to the labile surface of the front teeth and/or gums of a subject, which strip is provided with one or more oral care compositions for delivery to the teeth and/or gums of the subject. It further relates to its use for delivery of compositions, specifically for whitening teeth. It further relates to use of the strip in combination with a dental device.
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LIGHT ACTIVATED TOOTH WHITENING SYSTEM, DEVICE AND METHOD

(WO2006107362) 12.10.2006 A61C 3/00 KHUBANI, Ajit
A light activated tooth whitening system and method including a light device having a light element for projecting light at a user's teeth and a lip retainer, which can be a retaining ridge. The lip retainer in conjunction with the user' s lips position the light element to direct light toward the user's teeth. The system and method may include an applicator, such as a mouthpiece, a dental tape or strip, or a brush, to apply a light activated tooth whitening composition to at least a portion of one of a user's teeth. The applicator can include composition retention areas for holding the composition and dispensing the composition onto the user's teeth by positioning the applicator proximate the user's teeth.
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COMPOSITION FOR ORAL USES

(WO2006106991) 12.10.2006 A61K 8/97 KOBAYASHI PHARMACEUTICAL CO., LTD.
[PROBLEMS] To provide a composition for oral uses which has an excellent GTase-inhibitory effect and can inhibit the formation of a bacterial plaque to prevent the dental caries effectively. [MEANS FOR SOLVING PROBLEMS] A composition for oral uses comprising an extract from a leaf, a stem, a root or a mixture thereof of a plant of the family Vitaceae, the genus Vitis.
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COMPOSITION FOR ORAL USE

(WO2006106990) 12.10.2006 A61K 8/97 KOBAYASHI PHARMACEUTICAL CO., LTD.
[PROBLEMS] To provide a composition for oral use which has an excellent GTase-inhibitory effect and can effectively prevent dental caries through the inhibition of the bacterial plaque formation. [MEANS FOR SOLVING PROBLEMS] A composition for oral use prepared by using an extract of a plant belonging to the genus Oenothera in the family Onagraceae with a polar solvent.
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FLUORINE ION-RELEASABLE COMPOSITION FOR DENTAL PURPOSES

(WO2006106838) 12.10.2006 A61K 6/08 KURARAY MEDICAL INC.
A fluorine ion-releasable composition for dental purposes comprising (a) an inorganic powder, (b) a fluorine ion-releasable substance, (c) a polymerizable monomer and (d) a polymerization initiator, the inorganic powder (a) comprising a complex particle comprising a base particle composed of an inorganic substance and a layer composed of a polysiloxane formed on the surface of the base particle, and the fluorine ion-releasable substance (b) comprising at least one component selected from the group consisting of ammonium fluoride, ammonium hydrogenfluoride, a metal fluoride, a polymer having a vinyl monomer bearing an acid fluoride group as the constitutional unit and a fluorine-containing phosphazene monomer. The composition can provide a h...
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CENTRIFUGAL BLOWER

(WO2006106744) 12.10.2006 F04D 29/28 MITSUBISHI HEAVY INDUSTRIES, LTD.
A centrifugal blower with reduced noise. The centrifugal blower has an impeller (2), a casing (3) receiving the impeller and forming a spiral flow path radially outside the impeller, and a drive device (4) for rotatingly driving the impeller about an axis (O). The impeller is constructed from a bottom plate (11), blades (12) arranged on the same circumference of the bottom plate, and a shroud (13) of a substantially annular plate shape, installed coaxial with the bottom plate with the blades positioned between the shroud and the bottom plate. The shroud is composed of an inclination section (16) approaching the bottom plate as it goes from the radially inside to the radially outside of the shroud, and a shroud side barrier wall (17) rising ...
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IMPROVED OPTICAL COMPOSITION FOR IMPRESSIONS OR REPLICAS OF SMALL OBJECTS

(WO2006105579) 12.10.2006 A61B 5/103 GRENNESS, Malcolm
A composition, apparatus and method for preparing a 3-D impression or replica of small objects. It is particularly aimed at the dental field and provides improved optical texture of an impression or replica of a small object to enable imaging by photogrammetry. The composition comprises a liquid curable polymer; macroparticles having a size greater than about 1 m in diameter and microparticles present in a size range of less than about 1 m such that the macroparticles and microparticles are present in a ratio in the range of between 5: 1 and 15:1 (by volume); wherein the impression or replica formed from the composition has a surface particle distribution effective to allow imaging by photogrammetry .
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ORAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR

(WO2006105260) 05.10.2006 A61Q 11/00 C2C TECHNOLOGIES LLC
The invention describes color changing toothpastes and mouthwashes which contains acid-base indicator(s) for interaction with the oral cavity to provide a color change indicative of treatment time.
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DIINDOLYLMETHANE-BASED COMPOSITIONS AND METHODS OF USE THEREOF FOR PROMOTING ORAL MUCOSAL AND BONE HEALTH

(WO2006105196) 05.10.2006 A61K 9/68 BIORESPONSE, L.L.C.
The present invention includes compositions and methods for the treatment and prevention of oral mucosal disorders and for promotion of bone health. In particular, the present invention describes new therapeutic and preventative uses for 3,3'-diindolylmethane (DIM), or a DIM-related indole, alone or in combination with anti-inflammatory agents and/or antibacterial agents, to treat oral mucosal disorders and promote bone health. The compositions of the invention are used to prevent and reverse oral mucosal disorders and bone loss (osteopenia and osteoporosis) associated with aging and chronic inflammation. Oral mucosal disorders include Periodontitis, gingivitis and related oral mucosal inflammation. Formulations of the compositions of the i...
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DEVICE FOR CLEANING TEETH CONTAINING A DENTAL FLOSS

(WO2006104470) 05.10.2006 A61C 15/04 STRELEC, Peter
A device for cleaning teeth consists of a handle (2), which is at one end provided with a holder of dental floss (4) with forked arms (3) for manual attaching the dental floss (4), and at its other end with a toothbrush (1). The toothbrush (1) is connected with the handle detachably or it forms with holder handle (2) one functional unit. The forked holder arm (3) is at its end provided with a clamping mechanism for attaching the dental floss (4). The dental floss (4) contains clamping elements, which divide it into working sections (4.1) and connecting sections (4.2).
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FOOD COMPOSITION FOR BINDING ACETALDEHYDE IN MOUTH AND IN DIGESTIVE TRACK, AND METHOD FOR THE PREPARATION OF THE COMPOSITION

(WO2006103316) 05.10.2006 A23L 1/305 BIOHIT OYJ
The object of the invention comprises food compositions, to which one or more acetalde- hyde-binding compounds are added. The purpose of the compositions is to reduce the amount of detrimental acetaldehyde in the area of the mouth, the pharynx, the oesophagus, the stomach, and the small and large intestines, and through this, to reduce the risk of developing cancers in these areas.
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ANTIBACTERIAL 5',5-DISUBSTITUTED 3,3'-DIALKOXY-2,2'-DIHYDROXY- 1,1'-BIPHENYL COMPOUNDS AND RELATED METHODS

(WO2006101864) 28.09.2006 A61K 31/09 COLGATE-PALMOLIVE COMPANY
The invention provides an antiplaque oral composition that includes an orally acceptable carrier; and an antibacterially effective amount of a compound of structure (I) In the structure, R1 and R2 are independently selected from a lower C1-4 alkyl group and R3 and R4 are independently an alkenyl or alkyl group having from 1 to 20 carbon atoms. Also included in the invention are toothpastes or tooth gels that include at least one humectant; at least one abrasive compound; and an antibacterially effective amount of the compound represented by the structure of formula (I). Also provided are methods of inhibiting bacterial growth in the oral cavity of an animal by application of the compound of formula (I).
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ANTIBACTERIAL 3',5-DISUBSTITUTED 2,4'-DIHYDROXYBIPHENYL COMPOUNDS, DERIVATIVES AND RELATED METHODS

(WO2006101818) 28.09.2006 A61K 8/34 COLGATE-PALMOLIVE COMPANY
The invention provides an antiplaque oral composition containing an orally acceptable carrier and an antibacterial effective amount of compound (I). In the structure, R1 and R2 are independently a hydrogen atom or a lower C1-4 alkyl group and R3 and R4 are independently an alkenyl or alkyl group having from 1 to 20 carbon atoms, with the proviso that R3 and R4 are not both 2-propenyl or n-propyl when R1 and R2 are both hydrogen atoms. Also included are oral compositions containing the compound (I).
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NOVEL USE

(WO2006100107) 28.09.2006 A23L 1/304 GLAXO GROUP LIMITED
Use of calcium in an acidic composition for oral administration as a liquid at elevated temperature in the range 40C to 80C, having a pH in the range 3.50 to 4.50 and calcium being present in an amount such that the molar ratio of calcium to acid is in the range 0.30 to 0.80, to inhibit the increase in dental erosion associated with temperature elevation.
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ALKYL SULFATE FREE AND ORTHOPHOSPHATE FREE DENTIFRICE COMPOSTION COMPRISING A FLUORIDE SOURCE AND A SILICA DENTAL ABRASIVE

(WO2006100071) 28.09.2006 A61K 8/25 GLAXO GROUP LIMITED
A dentifrice composition is described for combating dental erosion and/or tooth wear comprising a fluoride ion source and a silica dental abrasive, the dentifrice having a Relative Dentine Abrasivity (RDA) value from 20 to 60 and a pH in the range 6.5 to 7.5 and being free of an orthophosphate buffer or a water soluble salt of a C10-18 alkyl sulfate.
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MECHANISM FOR OPENING AND CLOSING TOOTHPASTE SUPPLY OF THE TOOTHBRUSH

(WO2006099694) 28.09.2006 A46B 11/00 SADIKOVIC, Sasenko
Mechanism (1) and (10) for opening and closing toothpaste supply from the conduit (8). With handle (1) in upper position, toothpaste can flow through elliptical opening to bristles (4). With handle (1) in lower position, toothpaste is blocked by blind part (9) .
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ECCENTRIC-SIMMETRICAL ROTARY GIRDER OF THE TOOTHBRUSH WITH ITS INTERNAL CONDUIT FOR THE TOOTHPASTE SUPPLY OF THE BRUSHES SHEAFS

(WO2006099693) 28.09.2006 A46B 11/00 SADIKOVIC, Sasenko
Eccentric-simmetrical rotary girder of the toothbrush with its internal conduit for the toothpaste supply of the sheafs including page 5 girder (1) which is contorted on two places so it could rotate (7) it is contort under 45. Through the girder (1) it is passing squeezed toothpaste (15) from the tube (3) which is in its holder (4). By squeezing the toothpaste from the tube and by passing through the conduit (6) it is coming toward the arrow (11) which is prolonging to the bottom (12) of the sheafs (13) of the brush (5). This girder is rotating in the direction of an arrow (18) for 365 in its casing (9) where the pad (8) is allowing him to firmaly lies in the constructed lid (2). The same function and application is shown on page...
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MECHANISM WITH HOLDER FOR THE TOOTHPASTE EXTRUDING FROM THE TUBE TOWARDS THE BRUSH

(WO2006099692) 28.09.2006 A46B 11/00 SADIKOVIC, Sasenko
Mechanism with holder for the toothpaste extruding from the tube towards the brush is including holder with a hollow part for tube inserting (3) page 5 fig. 2 and octogonal wheel (6) fig 5. On the page 6 fig.2 we can see inserted tube (2) inside the widen fork (3) which is by the twisting of the octogonal wheel (5) towards the arrow (4) is twisting around the fork fig 1 where the fork is contracting toward the arrow (12) fig. l and 2. With that twist of the tube with mechanism (4) around the fork as we can see on the figure 1 toothpaste, from the tube fig 2 is automatically extruding in the direction of the arrow (6) and conduit inside the girder (8) is penetrating to the end of the toothbrushes sheafs.
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COMPATIBLE TOOTHBRUSH FOR THE TEETH CARE AND HYGJENE WIT TOOTHPASTE TUBES HOLDER AND GIRDER OF THE TOOTHBRUSH

(WO2006099691) 28.09.2006 A46B 11/00 SADIKOVIC, Sasenko
Compatible toothbrush for care and hygiene of the teeth with conduit in its girder and toothpaste tubes holder is assembled of, page 5 fig.l, holder (4) which is carrying the tube (3) with the paste (8) which is, by pressing the tube (3) with fingers toothpaste is coming out (8) from the tube (3) which is travelling in the direction of the arrow (15) towards the coil (10) and it is going through the conduit (2) to the rooths (16) of the sheafs (6) of the toothbrush and above them (5) . On the same page fig.3 we can see hygienic protective cover (11) which is over the coil (13) fig.2 wind up on the coil (14) of the holder and toothbrushes girder with internal conduit the holder has installed grooves which is covering over the other gr...
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DENTAL BARRIER COMPOSITION

(WO2006096893) 14.09.2006 A61K 6/00 MARX MANAGEMENT CC
The invention provides a dental barrier composition for use in dental procedures, said composition including one or more microbicidal and/or microbistatic substance or composition, one or more carrier fluid having a viscosity between 15 mPa.s and 10 000 mPa.s, said carrier including one or more thickening, gelling, and or suspending agents selected from the group including, but not limited to, hydroxy propyl methyl cellulose, hydroxy ethyl cellulose, methyl cellulose, chitosan, glycerol, silica or fumed silica, guar gum, povidon, pectin, gelatine, and ceratonia, provided that where hydroxy ethyl cellulose is used it is used in combination with at least one other carrier. The invention further provides for use of the composition and a method...
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DISPENSING BRUSH

(WO2006096355) 14.09.2006 A47L 13/22 GLOVER, Scott, J.
A dispensing toothbrush includes a toothpaste reservoir chamber formed in a handle having a paste advancing piston disposed therein. The handle may be closed at one end by a floss dispenser. The handle is connected to a brush head and adapter assembly which includes a manual actuator which is disposed for sliding movement in the adapter to displace a plunger which reduces the volume of a chamber in the plunger to discharge paste into a feed tube. The suction plunger may be biased by a spring or include an elastic memory sufficient to restore the plunger to its original position whereby paste is drawn from the paste reservoir into the plunger chamber. A rubber cover is disposed over the actuator and is also sealingly engageable with a remova...
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HEAT-RESISTANT FILLING AND PROCESS FOR PRODUCING THE SAME

(WO2006095505) 14.09.2006 A23D 7/00 FUJI OIL COMPANY, LIMITED
A filling which is superior in heat resistance to conventional products and has satisfactory meltability in the mouth. The heat-resistant filling is a fat composition (A) which is obtained by mixing a fat having a melting point not higher than the body temperature with a saturated fatty acid triglyceride and whipping the mixture or is a fat composition (B) which comprises that fat composition further containing a non-fat ingredient, wherein the fat composition (A) has a specific gravity of 0.2-0.5 or the fat composition (B) has a specific gravity of 0.2-0.9.
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METHOD AND COMPOSITION FOR REPAIRING EPITHELIAL AND OTHER CELLS AND TISSUE

(WO2006093881) 08.09.2006 C12N 5/00 REGENETECH, INC.
The present invention is directed to the TVEMF-expansion of mammalian blood stem cells, preferably CD34+/CD38-cells, to compositions resulting from the TVEMF-ex-panded cells, and to a method of treating a disease or condition or repairing tissue of skin, mouth or ear with the compositions.
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AQUEOUS DISINFECTANTS AND STERILANTS

(WO2006093792) 08.09.2006 C11D 3/39 SOLUTIONS BIOMED, LLC
The present invention is drawn to disinfectant or sterilant compositions, which are human safe, e.g., food grade or food safe. In one embodiment, an aqueous disinfectant or sterilant composition can comprise an aqueous vehicle, including water, from 0.001 wt% to 50 wt% of a peracid, and from 0.001 wt% to 25 wt% of a peroxide. Additionally, from 0.001 ppm to 50,000 ppm by weight of a transition metal based on the aqueous vehicle content can also be present. When the transition metal or alloy is present only in the form of an ionic metal or salt, the composition can be substantially free of aldehydes. Alternatively or additionally, the transition metal can be in the form of a colloidal transition metal and aldehydes may or may not be included...
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SILANOL BASED DENTAL TREATMENT

(WO2006093777) 08.09.2006 A61K 6/00 KANCA, John, III
Etching compositions, curable compositions, packaged products and methods of use for the treatment of bone substrate, i.e., teeth, are described. The etch solutions generally include an aqueous acidic solution with an ethylenically unsaturated monomer and a silane. The methods of the invention provide the ability to modify a bone or bone-like surface so that the curable composition, such as an adhesive resin, can be used in combination with a restorative material.
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NOVEL ADHESIVE MATERIALS, MANUFACTURING THEREOF, AND APPLICATIONS THEREOF

(WO2006092798) 08.09.2006 C08L 101/00 TECHNION RESEARCH &DEVELOPMENT FOUNDATION LTD.
A novel composition-of-matter, method of manufacturing thereof, and applications thereof as an adhesive, in a wide variety of different fields, and in particular, in the health care fields of medicine, dentistry, and veterinary science, for use by health care providers, such as medical, dental, and veterinary, surgeons, in procedures for reattaching or repairing body parts or components thereof, such as tissue, of (human or animal) subjects, especially under wet conditions, for example, involving adhesion of wet surfaces. The composition is comprised of a cross-linked form of a water miscible polymer, and at least one phloroglucinol type compound selected from the group consisting of: phloroglucinol, a derivative of phloroglucinol, and a po...
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DENTAL MODELING AND ARTICULATING SYSTEM AND METHOD

(WO2006091982) 31.08.2006 A61C 11/00 JUNG, Yunoh
A dental articulating system (300) configured to duplicate at least a portion of a patient's mouth for use in producing a dental prosthesis includes a tray base (112) and a plate (140) magnetically coupleable together. A magnet recess (125) is carried by either the tray base or the plate, and a ferrous recess (145) is carried by the other of the tray base or the plate. The magnet recess receives a magnet element (130) therein and the ferrous recess receives a ferrous element (180) therein. The magnet recess has a magnet opening (184) configured to receive the magnet therethrough, the magnet opening facing away from the ferrous recess so that at least a Hp (170) is disposed between the magnet recess and the ferrous recess.
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THREE PART DENTAL BONDING COMPOSITIONS AND METHODS

(WO2006091855) 31.08.2006 A61K 6/00 KANCA, John, III
Three part bonding compositions that include an etching solution, a preparative solution, and a curable composition, as well as packaged products and methods of use for the treatment of bone substrate, i.e., teeth, are described. The etch solutions generally include an inorganic acid, an organic acid, an ethylenically unsaturated functional monomer and, optionally a solvent, and water. The preparative solutions generally include an ethylenically unsaturated functional monomer, at least one polyethylenically unsaturated functional crosslinking monomer, a photo initiator, and at least one solvent. The curable composites include reactive monomers and crosslinking agents that are effective to adhere to the surface of the treated substrate. The ...
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FLASK FOR MOLDING DENTURES

(WO2006090952) 31.08.2006 A61C 13/20 CHOI, Beak-Chil
A flask for molding dentures is disclosed. The flask includes an upper plate (10) having an injection pipe (12), an ejector (18), an air hole, guide pins (14) and nuts (15), a lower plate (20) having an injection pipe (22), an ejector (28), an air hole, guide holes (24), and bushings (25), a connection pipe (45) connected to the injection pipes (12 and 22), a pressing part (30) having pressing pieces (31 and 32) coupled with a spring (33) and a cap nut (35) and accommodated in the connection pipe (45), and a conduit part (40) having a first inner member (41), a second inner member (42), a third inner member (43), and fourth inner members (44). T he flask has a simple structure and prevents reduced stiffness of dentures due to bubbles and in...
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FRUIT CELL CULTURE EXTRACT FOR TREATING INFLAMMATION

(WO2006090388) 31.08.2006 A61K 36/87 THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE &RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION, (A.R.O.), VOLCANI CENTER
A novel pharmaceutical composition formulated for mucosal delivery for the treatment of inflammatory disorders is disclosed and methods of generating same.
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FOAMING COMPOSITIONS AND METHODS

(WO2006089028) 24.08.2006 A61K 6/00 LAB39, LLC
An effervescent foamable two-component oral care composition in which a first component contains an acid, and a second component contains an alkaline source such as a carbonate; wherein one or both of the first and second components also contains a surfactant; and, wherein the first and second components are combinable to form an effervescing oral care foam. Also disclosed is a tissue treatment composition comprising an effective amount of a nitric oxide, nitroxyl or nitrogen oxide composition for color effect of the tissue.
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ANTI-CORROSION DETERGENT COMPOSITIONS AND USE OF SAME IN CLEANING DENTAL AND MEDICAL INSTRUMENTS

(WO2006086875) 24.08.2006 C11D 1/722 SCICAN
A novel method for cleaning dental and medical instruments is disclosed, in which a cleaning solution including a low-residue corrosion inhibitor is used not only in a wash stage of the cleaning cycle, but also in at least one subsequent rinse cycle, to optimize both cleaning and rust prevention. A novel cleaning solution particularly suited to this method has a neutral to alkaline pH and comprises in aqueous solution a low-foaming surfactant and a corrosion inhibitor selected from the group of C4-C16 alkyl pyrrolidones and C1-C18 alkylamines.
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COMPLETE AIRWAY STABILIZATION SYSTEM

(WO2006086368) 17.08.2006 A61M 16/04 KANOWITZ, Arthur
An endotracheal airway is established using an endotracheal tube (100) having an exterior retention structure (100) defined by a series of longitudinally spaced recesses separated by projections. A variably-sized orifice in a faceplate (200) constricts within a recess and contacts the projections to create a barrier against movement of the endotracheal tube. The faceplate is retained on the mouth by connection to a stabilization collar (500) which surrounds the neck of the patient to restrain against flexion and extension which could reposition the endotracheal tube from its desired position.
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STABLE TOOTH WHITENING GUM WITH REACTIVE INGREDIENTS

(WO2006086061) 17.08.2006 A61K 8/20 CADBURY ADAMS USA LLC
Oral compositions including an encapsulated active component(s) are provided. The oral compositions include a carrier composition including a first reactive component. The oral compositions also include an active composition. The active composition includes at least one active component encapsulated in a coating. The coating includes a hydrophilic material and at least one second reactive component, wherein an interaction between the first and second reactive components preserves the activity and/or availability of the active.
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PSYCHOGENIC PAIN THERAPEUTIC AGENT

(WO2006085688) 17.08.2006 A61K 45/00 JAPAN SCIENCE AND TECHNOLOGY AGENCY
It is intended to provide a psychogenic pain therapeutic agent that exerts an excellent therapeutic effect on psychogenic pain which is an intractable disease. More specifically, it is intended to provide a psychogenic pain therapeutic agent comprising a phenylethanolamine N-methyl transferase (PNMT) inhibitor such as DCMB (()-2,3-dichloro-a-methylbenzylamine) as an active ingredient, a pharmaceutical composition for psychogenic pain therapy comprising the PNMT inhibitor as an active ingredient, and a therapeutic method for psychogenic pain using the PNMT inhibitor.
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REMEDY FOR NEUROGENIC PAIN

(WO2006085686) 17.08.2006 A61K 31/5513 JAPAN SCIENCE AND TECHNOLOGY AGENCY
It is intended to provide a remedy for neurogenic pain exerting an excellent therapeutic effect on neurogenic pain which is an intractable disease. More specifically speaking, it is intended to provide a remedy for neurogenic pain which contains, as the active ingredient, a PPAR antagonist (in particular, a PPAR?-selective antagonist such as 2-chloro-5-nitro-N-phenylbenzamide), a medicinal composition for treating neurogenic pain which contains, as the active ingredient, a PPAR antagonist, a method of treating neurogenic pain with the use of a PPAR antagonist and so on.
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DENTAL RESTORATION MATERIAL COMPOSITION

(WO2006085682) 17.08.2006 A61K 6/083 SUN MEDICAL CO., LTD.
A dental restoration material composition comprising a polymerizable monomer having three or more partial polyester chains with a polymerization group bonded thereto in each molecule. There is provided a highly tough dental restoration material composition for use in a tooth crown resin, resin prosthetic materials such as an artificial tooth, filling materials such as a composite resin, and other resin dental materials, which dental restoration material composition excels in mechanical properties, especially toughness, and excels in impact resistance and shatter resisting properties.
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SCENTED DISPENSING FITMENT FOR BOTTLES DELIVERING HOUSEHOLD CARE LIQUID PRODUCTS

(WO2006084572) 17.08.2006 B65D 47/06 UNILEVER PLC
A package (2) for a liquid household care composition is provided which eliminates any foul smelling odors emanating from the composition. The package includes a unitarily molded bottle (4) having a container area (6) formed from plastic walls and an open and a closed end, the open end including a neck area (10) with an open mouth (9). A cap (12) is present for reclosably covering the open mouth. A dispensing fitment (14) such as a pour spout (16) is molded separate from the bottle and supported adjacent the neck area. Plastic walls (20) of the fitment include an aroma control agent, advantageously present within an encapsulating matrix. Walls of the bottle are substantially free of the aroma control agent.
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MEDICAL/DENTAL SUCTION NOZZLE HOLSTER

(WO2006084108) 10.08.2006 B44D 3/12 PATIENT SHIELD CONCEPTS, LLC
A suction nozzle holster device (10) is provided with three possible operating positions through the use of a mounting channel component (18) having a left (60), a center (58) and a right (56) key plate/key nub (6O',58',56') system that can each be respectively inserted into a cooperating keyway slot (22A)/nub receiver (30) opening system mounted on a rear portion (22) of a holster mounting component (16) of the device (10). This arrangement gives the holster device (10) three distinct operating positions.
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DENTAL BLEACHING COMPOSITIONS HAVING A PROTECTIVE COATING APPLIED THERETO

(WO2006083525) 10.08.2006 A61K 8/20 ULTRADENT PRODUCTS, INC.
A dental bleaching material comprises a dental bleaching composition that includes a dental bleaching agent and a thickening agent and a protective coating on a surface of the dental bleaching composition that includes a complex of polyvinyl pyrrolidone (PVP) and hydrogen peroxide (H2O2). The bleaching composition may be a gel or solid. The protective coating may be a powder or a solid shell. A dental bleaching device (100) includes a barrier layer (102), such as an initially flat strip or a dental bleaching tray (110), a dental bleaching composition (112) adjacent to the barrier layer (102), and a protective coating on a surface of the dental bleaching composition comprising the complex of PVP and H2O2.
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DENTAL TRAY SYSTEM WITH RELEASABLE HOLD INNER AND OUTER DENTAL TRAYS

(WO2006083524) 10.08.2006 A61C 5/00 ULTRADENT PRODUCTS, INC.
A dental treatment system (100) used to treat (e.g., bleach) a person's teeth. The inventive system includes an inner dental treatment tray (102) having a tray configuration so as to fit over at least a portion of a person's upper or lower dental arch. The inner dental treatment tray (102) is sufficiently thin and flexible so as to at least partially conform to a person's teeth without heating when used in combination with a dental treatment and/or adhesive composition. The dental treatment system (100) includes an outer support tray (104) positioned adjacent to the inner dental treatment tray (102) so as to maintain the inner dental treatment tray (102) in the tray configuration prior to placement of the inner dental treatment tray (102) o...
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TOOTHBRUSH

(WO2006082799) 10.08.2006 A46B 3/06 SUNSTAR INC.
A toothbrush which comprises a brush main body (10) made of a synthetic resin and having a bristle base (12) and bristles (2) made of a thermoplastic resin which have been fusion-bonded to the bristle base to constitute a bristled part, wherein the bristles (2) constituting the bristled part at least partly comprise: tapered bristles which are bristles having split free ends, the split free ends having been tapered beforehand; tapered bristles which have a sectional shape having a core-sheath structure or sea-island structure; or tapered bristles in each of which a core bristle comprising a core or island part has been formed beforehand so as to be exposed at the free end. The toothbrush has excellent suitability for bristle insertion into ...
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MELT GRANULATION OF A COMPOSITION CONTAINING A CALCIUM-CONTAINING COMPOUND

(WO2006082499) 10.08.2006 A61K 9/16 NYCOMED PHARMA AS
A novel method for the preparation of a tablet comprising a calcium-containing compound, the method involves a melt granulation process by which a sugar alcohol is melted and embeds the calcium-containing compound so that a sufficient taste- masking of the chalkiness is substantially achieved and an unpleasant mouth feel of the calcium-containing compound is substantially avoided, while at the same time obtaining a low tablet volume. The method of the invention is especially suitable for the manufacturing of tablets having a high load of a calcium-containing compound.
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DENTAL DEVICE FOR USE IN THE OBTURATION OF A ROOT CANAL

(WO2006082078) 10.08.2006 A61C 5/04 DENTSPLY DETREY GMBH
Kit-of-parts containing (i) a dental device for use in the obturation of a root canal which comprises a tapered obturating point portion integrally connected at the distal end of a functional portion, whereby the functional portion comprises (a) a neck portion adjacent to the obturating point portion, and (b) a handle portion, and (ii) a dental sealant composition, wherein the dental device is made of a material obtainable by curing a composition containing one or more curable components contained in the dental sealant.
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APPLIANCE FOR WEANING OFF SUCKING

(WO2006082015) 10.08.2006 A61J 17/02 DR. HINZ DENTAL-VERTRIEBS- UND VERWALTUNGSGESELLSCHAFT MBH
The invention relates to an appliance (1) for weaning off sucking, said device comprising an oral vestibule plate (2) to be introduced into the mouth and lateral biting rails (4, 5) for the molar teeth, provided on both sides of the tooth-side inner side of the oral vestibule plate (2). The aim of the invention is to stop damaging sucking habits, to prevent the malpositioning of teeth, and to repair deformities already created. To this end, the front region between the biting rails is kept free so that foreign bodies cannot be inserted between the front teeth during the use of the inventive appliance.
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MULTIPHASE TOOTHPASTE COMPOSITION

(WO2006081934) 10.08.2006 A61K 8/02 UNILEVER N.V.
Multiphase toothpaste composition comprising a first phase disposed co-axially within a second, visually clear gel phase, the first phase constituting up to 25% by volume of the toothpaste composition.
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MULTIPHASE TOOTHPASTE COMPOSITION

(WO2006081933) 10.08.2006 A61K 8/02 UNILEVER N.V.
Multiphase toothpaste composition comprising a first phase disposed co-axially within a second phase, each of the phases having a specific gravity of from 1.1 to 1.5 g/ml.
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MULTIPHASE TOOTHPASTE COMPOSITION

(WO2006081926) 10.08.2006 A61K 8/19 UNILEVER N.V.
Multiphase toothpaste composition comprising a first phase disposed co-axially within a second, visually clear gel phase, the second phase comprising from 1ppm to 100 ppm of a pigment.
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TOOTHPASTE

(WO2006081924) 10.08.2006 A61Q 11/00 UNILEVER N.V.
A toothpaste which comprises first and second compositions, the first and second compositions comprising water, humectant and thickener and the second composition disposed coaxially within the first composition, the first composition being a gel and the second composition being opaque, the second composition comprising an opacifier at y% by weight of the second composition and the first composition comprising 0.2 to 2.0y% by weight of the first composition more thickener than is present as a weight percent of the second composition.
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MULTIPHASE TOOTHPASTE COMPOSITION

(WO2006081913) 10.08.2006 A61K 8/19 UNILEVER N.V.
Multiphase toothpaste composition comprising a first phase disposed co-axially within a second phase, the second phase being sufficiently clear such that the first phase can be visually perceived therethrough, the second phase comprising agglomerates .
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MULTIPHASE TOOTHPASTE COMPOSITION

(WO2006081912) 10.08.2006 A61K 8/02 UNILEVER N.V.
Multiphase toothpaste composition comprising a first phase disposed co-axially within a second phase, each of the phases having a viscosity of from 180 000 to 250 000 mPa.s.
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TOOTHPASTE COMPOSITION

(WO2006081867) 10.08.2006 A61K 8/25 UNILEVER N.V.
A toothpaste composition comprising an inner phase disposed substantially coaxially within an outer phase, the inner phase constituting from 60 to 99.9% by volume of the composition, the outer phase being a gel and constituting from 0.1 to 40% by volume of the composition.
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OILY FOOD MATERIAL

(WO2006080418) 03.08.2006 A23G 1/00 FUJI OIL COMPANY, LIMITED
[PROBLEMS] To develop by an easy method an oily food material which, when eaten, gives a satisfactory and novel feeling in the mouth and which has high heat resistance. [MEANS FOR SOLVING PROBLEMS] In the oily food material, the particle size of solid ingredients other than the fat is kept at 30 m or more, which is larger than in ordinary oily food materials represented by chocolate, and the proportion of StUSt to all fat is regulated to 30 wt.% or higher. Furthermore, the fat content in the oily food material is 20-55%. Due to this constitution, the oily food material has significantly improved meltability in the mouth while retaining high heat resistance. It can be produced by an easy method.
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ELECTRIC CLEANER AND SUCTION MOUTH BODY

(WO2006080383) 03.08.2006 A47L 9/04 TOSHIBA TEC KABUSHIKI KAISHA
A floor brush for an electric cleaner, in which cleaning performance by a rotating cleaning body is improved while costs of the floor brush is suppressed. When a lower end section of a front cover (18) comes in contact with an obstruction and is rotated backward, a rear face of the front cover (18) comes into contact with a rotating brush (21) and simultaneously the lower end section approaches a floor surface (F). This causes an opening (38) to be narrower, increasing a load in a rotating cleaning body chamber (22) to reduce suction from the rotating cleaning body chamber (22) side. As a result, the volume of suction air from a suction mouth is relatively increased to increase rotational force of an air turbine (27a). As a consequence, in ...
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0-(3-PIPERIDINO-2HYDROXYPROPYL)NICOTINIC AMIXODIME FOR TREATING LESIONS IN THE ORAL CAVITY

(WO2006079910) 03.08.2006 A61K 31/445 N-GENE RESEARCH LABORATORIES INC.
The invention refers to the use of of 0-(3-piperidino-2-hydroxypropyl)nicotinic amidoxime or a pharmaceutically suitable acid addition salt thereof for the preparation of a pharmaceutical composition or a mouth and tooth care composition suitable for the treatment of lesions in the oral cavity.
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ANTACID LOZENGE CONTAINING MICRONIZED SALTS

(WO2006079903) 03.08.2006 A61K 9/20 MCNEIL- PPC, INC.
An organoleptically acceptable antacid lozenge including at least one antacid present in the form of micronized particles having a particle size of less than about 0 microns. The lozenge is a solid oral composition capable of dissolving slowly in the mouth for long lasting administration of an antacid at a sustained or slow release rate. The lozenge is non-gritty, smooth textured, and does not irritate the oral mucosa.
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FORMULATIONS OF PEPTIDES FOR PERIODONTAL AND DENTAL TREATMENTS

(WO2006078464) 27.07.2006 A61K 38/00 ACOLOGIX, INC.
Methods to treat the defects in skeletal tissues characterized by protecting the marrow cells adjacent to the defects from apoptotic and/or necrotic cell death are disclosed. The methods provide additional benefits which are to reduce inflammation and irritation in the marrow tissues and assist promoting new skeletal tissue formation to an application of a simple skeletal formation or regeneration activity such as a bone growth factor. The methods may involve application of pharmacologically active peptidic compounds comprising about 15 to about 28 amino acids in their sequences characterized by containing at least one of an integrin binding motif such as an RGD sequence, a glycosaminoglycan attachment motif, and/or a calcium binding motif....
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METHOD IN CONNECTION WITH THE CLEANING/DISINFECTION OF BOTTLES, AND BOTTLE TRAY AND SUPPORT DEVICE THEREFORE

(WO2006078206) 27.07.2006 B08B 9/42 HARRY HOLMS AKTIEBOLAG
A method in connection with the cleaning/disinfection of bottles, comprising the steps: - placing at least one bottle (4A; 4B; 4C) in a bottle-holding device (200, 300), which bottle-holding device (200, 300) is provided with base (204', 203'') and side (203', 205, 209, 206) supports, respectively, for the bottle (4A; 4B; 4C), - placing a cover (100) on top of the bottle-holding device (200, 300), in order to vertically fix said bottle (4A, 4B, 4C), whereby the mouth (4A', 4B', 4C') of the bottle is positioned some distance above the upper limiting surface (311) of the bottle-holding device (200, 300), said bottle-holding device (200, 300) being arranged to comprise a separate bottle tray (200) and a separate support device (300), for the p...
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MEDICAL RESIN COMPOSITION, PROCESS FOR PRODUCING RESIN COMPOSITION AND PROCESS FOR PRODUCING MOLDED ITEM

(WO2006077944) 27.07.2006 C08F 2/44 NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY
A medical resin composition is produced by mixing a powder of polymer (A) composed of ester-group-having repeating units with a solvent of vinyl ester monomer (B) with = 6 carbon atoms and thickening the mixture, optionally further advancing a polymerization reaction. The thus produced resin composition inhibits leaching of irritative substance, reduces any adverse effects on human body by endocrine inhibitors, etc. and can be prepared with high operational efficiency. This resin composition is suitable for use in dental resin compositions, such as a mucous membrane conditioning material, a functional impression material, a back lining material, a denture base material and a mouthpiece material.
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SYRINGES

(WO2006077392) 27.07.2006 A61C 9/00 ASTEK INNOVATIONS LIMITED
A syringe for dispensing a viscous settable material such as dental impression material has a tubular body (1 ) with an internal chamber (4), a plunger (2) movable through an open distal inlet end (5) along the chamber (4), and a nozzle (3) connected to an open proximal outlet end (6) of the chamber. The outlet end (6) is wide relative to the chamber cross- section and the nozzle can be detached to facilitate cleaning after use. The nozzle (3) when detached, may be displaceable from the outlet end (6) to the inlet end (5) to remove residual material due to a close scraping action between a rim (13a) on the nozzle (3) and the interior surface of the chamber (4). The nozzle may also be non-removable so that cleaning can be readily effected du...
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FLUID CONDITIONING SYSTEM

(WO2006074486) 13.07.2006 A61C 5/00 BIOLASE TECHNOLOGY, INC.
A fluid conditioning system is adapted to condition the fluid used in medical and dental cutting, irrigating, evacuating, cleaning, and drilling operations. The fluid may be conditioned by adding flavors, antiseptics and/or tooth whitening agents such as peroxide, medications, and pigments. In addition to the direct benefits obtained from introduction of these agents, the laser cutting properties may be varied from the selective introduction of the various agents.
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TWO-COMPONENT DENTAL WHITENING COMPOSITIONS

(WO2006073559) 13.07.2006 A61Q 11/00 DISCUS DENTAL IMPRESSIONS INC
A two-component whitening system has a de-sensitizing effect as well as re-mineralizing capability. The system may be an unfoamed, a foamed or a foamable composition. The system has a first component with at least one peroxide compound, at least one source of phosphate and at least one gelling agent; and a second component with at least one source of calcium, strontium and/or mixtures thereof. The second component may also contain at least one gelling agent, and the composition maybe present as a foam or is foamable. The composition may be packed in a two-compartment syringe.
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OREGANO ORAL CARE COMPOSITIONS AND METHODS OF USE THEREOF

(WO2006071755) 06.07.2006 A61Q 11/00 COLGATE-PALMOLIVE COMPANY
A multi-benefit oral composition is provided. The oral composition is efficacious as an antibacterial, antiplaque, anti-inflammatory, anti-oxidant, and anti-halitosis oral composition. The active ingredient has one or more active compounds from an extract of oregano. The oral composition can be in the form of a mouth rinse; a dentifrice, including toothpaste, gels, powders; animal products; a film; or confectionaries, such as lozenges, and the like. Methods of making and using the oral composition are also provided.
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INSTANT TOOTH WHITENING WITH SILICONE RESIN AND SILICONE ADHESIVE

(WO2006071677) 06.07.2006 A61K 8/24 COLGATE-PALMOLIVE COMPANY
A tooth whitening composition for imparting a natural white appearance to dental enamel, comprising: a whitening particulate comprising hydroxyapatite and a delivery system comprising a silicone resin and a silicone adhesive. Methods of imparting whiteness to a tooth in a mammal are also provided.
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METHOD OF REDUCING ORAL TISSUE INFLAMMATION USING MAGNOLIA EXTRACT

(WO2006071653) 06.07.2006 A61K 36/57 COLGATE-PALMOLIVE COMPANY
A method for treating a mammal having oral tissue inflammation is provided, where the inflamed oral tissue is contacted with a safe, efficacious, non-irritating oral composition having an anti-inflammatory agent comprising a magnolia extract. The magnolia anti-inflammatory active ingredient reduces one or more mediators of inflammation and reduces inflammation in oral tissue. The oral composition can be in the form of a mouth rinse; dentifrice, including toothpaste, gels, powders, lozenges; medicament gel; animal products; and the like.
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OXIDATION RESISTANT DENTIFRICE COMPOSITIONS

(WO2006071404) 06.07.2006 A61K 8/97 COLGATE-PALMOLIVE COMPANY
Low water tooth pastes contain a variety of plant extracts. The oral or dentifrice compositions containing humectants, abrasive compounds, and a variety of plant extracts, such as rosemary and green tea extracts, along with an additional antioxidant component. Examples of antioxidants include stannous compounds, sodium meta-bisulfite, BHT, ammonium sulfate, and potassium stannate. The compositions are resistant to browning. The invention also provides methods for promoting oral health of a subject animal comprising applying a composition as discussed above to the oral surfaces of the animal.
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FINGER GLOVE WITH SINGLE SEAM

(WO2006071316) 06.07.2006 A46B 5/04 KIMBERLY-CLARK WORLDWIDE, INC.
A single seam finger glove that may fit onto a human finger is provided. The finger glove has a cavity so that it may easily be put on to a finger by a user and is formed by bonding together at least one nonwoven web to itself to form a tubular structure. The single seam finger glove is less irritating to the mouth of a user since it has half the seam area. Additionally, the single seam finger glove successfully prevents the formation of stiff seams along the edge so that seams will not cause abrasion or damage to the areas where the glove is intended to be used. Additionally, the single seam glove disclosed can have flush seams, which further reduces the stiffness along the seams so that the user feels more comfortable while wearing the gl...
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DENTAL/MEDICAL ANXIETY/PHOBIA REMEDIATION PROTOCOL

(WO2006071268) 06.07.2006 A61N 1/34 STAFFEL, Edward, R.
A protocol or procedure is provided for lowering sympathetic nervous system arousal in a person in order to prepare that person for a medical or dental procedure. First, a therapeutic dosage of one or more neurotransmitter supplements (220), such as a gamma aminobutyric acid formulation (122), a tryptophan-derived neurotransmitter (124), and dehydroepiandrosterone (126) are sublingually administered (120) to the patient (250). After a period of time for the formula dosage to take effect, gelled electrodes (245) are placed adjacent or below the mastoid. The gelled electrodes (245) are connected to a cranial electrotherapy stimulation device (240) that administers (130) a sub-sensation level current to the patient (250). Also, a noise dampeni...
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POWER TOOTHBRUSH USING ACOUSTIC WAVE ACTION FOR CLEANSING OF TEETH

(WO2006070296) 06.07.2006 A61C 17/20 KONINKLIJKE PHILIPS ELECTRONICS N.V.
The toothbrush includes a handle portion and a brushhead assembly which comprises a head portion and a stem portion. The head portion includes a bellows-like acoustic action member for creating acoustic wave action as it moves in and out in response to an acoustic driving force. A drive system is located in the handle and includes an audio speaker-type assembly to create acoustic waves which are transmitted through a transmission line to the acoustic action member. The acoustic action member is driven toward and away from the teeth when the toothbrush is operatively positioned within the mouth. The action of the acoustic member is directly or indirectly coupled to the fluid in the mouth, producing a foam which couples shear forces between t...
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NANOPARTICLE COMPOSITION AND METHODS FOR SYNTHESIS THEREOF

(WO2006069419) 06.07.2006 A61K 9/51 ICEUTICA PTY LTD
The present invention relates to improved therapeutically active nanocomposite microstructure compositions, including nanoparticle compositions and nanoparticle preparations. Preferred embodiments include nanoparticle compositions comprising nanoparticles of a therapeutically active agent dispersed in a carrier matrix. The invention also relates to a method for preparing said compositions and preparations using solid-state mechanochemical synthesis. Further, it relates to therapeutic products produced using said compositions and to methods of treatment using the compositions.
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ANTIBACTERIAL AND ANTI-INFLAMMATORY ORAL CARE COMPOSITION

(WO2006069209) 29.06.2006 A61K 8/97 COLGATE-PALMOLIVE COMPANY
An efficacious antibacterial and anti-inflammatory oral composition is provided having an active ingredient combination comprising one or more active compounds from an extract of magnolia and an extract of hops. Preferably, the active compounds from magnolia extract comprise honokiol and magnolol, and the active compounds from hops extract comprise hexahydrogenated beta acids. The oral composition can be in the form of a mouth rinse or dentifrice, including toothpaste, gels, powders, confectionaries, lozenges, animal products, and the like. Methods of making and using the oral composition are also provided.
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DENTAL ILLUMINATION DEVICE WITH SINGLE OR MULTIPLE TOTAL INTERNAL REFLECTORS (TIR)

(WO2006069112) 29.06.2006 A61C 1/00 WEST, John
The present invention relates generally to a device that attaches to one or more Light Emitting Diode (LED) light source(s) to transmit and distribute light energy simultaneously across the arches of upper and lower teeth for dental tooth whitening and photo initiation of light curing resins while at the same time retaining the benefits of the light source(s) to be used for individual tooth whitening and curing.
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ANTI-CARIES ORAL CARE COMPOSITION WITH A CHELATING AGENT

(WO2006068753) 29.06.2006 A61K 8/19 COLGATE-PALMOLIVE COMPANY
An oral care compositions comprises a water-soluble calcium salt, a fluoride-providing agent, and a chelating agent. Methods of treating or preventing dental caries are also provided.
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ORAL CARE MALODOR COMPOSITION

(WO2006068752) 29.06.2006 A61K 8/92 COLGATE-PALMOLIVE COMPANY
An oral odor control agent admixture of generally equivalent proportions of thymol, anise, fennel, basil, and juniperberry essential oils shows efficacy as an odor control agent in oral care for control of garlic odor.
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ANTI-CARIES ORAL CARE COMPOSITION WITH XYLITOL

(WO2006068750) 29.06.2006 A61K 8/34 COLGATE-PALMOLIVE COMPANY
An oral care composition comprises xylitol and a water-soluble calcium salt for caries prevention. Wherein said xylitol and said calcium salt are present in a weight ratio of at least 10:1. Methods of treating and preventing dental caries are also provided.
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GAS-ASSISTED SYSTEM FOR FLUID DROPLET GENERATION IN AN ORAL CARE SYSTEM

(WO2006067760) 29.06.2006 A61C 17/028 KONINKLIJKE PHILIPS ELECTRONICS, N.V.
An oral care system using a stream of fluid droplets for cleaning teeth includes a hand-held portable oral care device having a handle portion with a nozzle at a forward end thereof, a source of dental fluid and a source of pressurized gas, between 10-30 bar, both located in the handle portion. The system also includes a base unit which includes a reservoir tank for pressurized air, a reservoir tank for fluid, and a compressor connected to the gas reservoir. The handle includes valves for controlling the release of pressurized gas and fluid from the handle to the nozzle. Connecting ducts are arranged from the fluid and pressurized gas source to the nozzle such as to accelerate the pressurized gas droplets from the nozzle to a desired veloci...
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COPY MILLING DEVICE FOR PRODUCING WORKPIECES THAT ARE USED IN PARTICULAR IN DENTAL TECHNOLOGY

(WO2006067630) 29.06.2006 A61C 13/00 STEGER, Heinrich
The invention relates to a copy milling device (1) for producing workpieces that are used in particular in dental technology. Said device comprises a carrier plate (3) for a model (21), a moulded blank (20), an arm (4), which can be pivoted about a horizontal axis that runs essentially perpendicular to its longitudinal direction and comprises a motor-driven machining tool (5) for machining a workpiece from the moulded blank (20) and a scanning device (6) for scanning the model, the machining tool (5) and the scanning device (6) being interconnected in a mechanically and synchronous manner. The invention also relates to a suspension device for the arm (4).
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LOCAL AND RESIDUAL APPLICATION SYSTEM FOR INTRA-ORAL MEDICATIONS

(WO2006066958) 29.06.2006 A61C 19/06 GADOR S.A.
A system of application for an infra-oral medication characterized by: An applicating cannula having a suitable angle in order to reach any place with lesion in the mouth. A container having a gel with adequate bioadhesive drainage to be inserted in periodontal pockets and mucosa folds that is screwed to the cannula. The composition of the gel consists of chiorhexidine digluconate alone and together with other active principles such as a bisphosphonate, an analgesic or anesthetic substance, antibiotic, antimycotic, an antiviral, steroidal or non-steroidal anti-inflammatory, a coagulant substance or one aimed to modulate local hemosthasis, a cicatrizing substance, among the most outstanding.
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ORAL COMPOSITIONS CONTAINING EXTRACTS OF ROSMARINUS AND RELATED METHODS

(WO2006065522) 22.06.2006 A61Q 11/00 COLGATE-PALMOLIVE COMPANY
Addition of rosemary extract to various dentifrice compositions results in tooth paste, mouth rinses, and other compositions that are suitable for treating and preventing a variety of oral disease including gingivitis, plaque build-up, and the like. Rosemary extract, containing major amounts or ursolic acid and carnosic acid, is added to dentifrice compositions so that the amount delivered to the oral cavity upon use is effective to provide an antibacterial, antioxidant, and/or anti-inflammatory effect. In various embodiments, the components of rosemary extract are combined with triclosan or other phenolic antibacterial agents to provide enhanced activity.
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ORAL CARE IMPLEMENT

(WO2006065496) 22.06.2006 A46B 15/00 COLGATE-PALMOLIVE COMPANY
An oral care implement with a soft tissue cleanser is provided to effectively cleanse the soft tissue of the mouth with comfort and a reduced risk of injury to the user. In one construction, a projection is formed of a combination of a hard material and a soft material. The hard material provides good stability for cleaning debris from the tongue or other tissue while the soft material provides comfort and a reduced risk of injury.
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TARTAR CONTROL ORAL CARE COMPOSITION CONTAINING EXTRACT OF MAGNOLIA

(WO2006065403) 22.06.2006 A61Q 11/00 COLGATE-PALMOLIVE COMPANY
A stable and efficacious antiplaque, anticalculus, and antigingivitis oral composition is provided having an antibacterial ingredient comprising one or more active compounds found in an extract of magnolia combined with an anticalculus system comprising tetrasodium pyrophosphate (TSPP) about 1 to about 2.5% and sodium tripolyphosphate (STPP) about 1 to about 10%. The oral composition can be in the form of a mouth rinse or dentifrice, including toothpaste, gels, powders, as well as confectionaries, lozenges, and the like. Methods of making and using the oral composition are also provided.
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OILY FOOD AND METHOD OF PRODUCING THE SAME

(WO2006064709) 22.06.2006 A23G 1/00 FUJI OIL COMPANY, LIMITED
[PROBLEMS] To develop an oily food suffering from less worsening in the meltability in the mouth and flavor development, which arises in association with the improvement in heat resistance, and to which the above functions can be imparted by a convenient method. [MEANS FOR SOLVING PROBLEMS] By controlling the composition rate of SOS to (SOO+SLS+SLO) to a specific level in the fat composition in preparing an oily food, worsening in the meltability in the mouth and flavor development, which arises in association with the improvement in heat resistance, can be lessened. Moreover, an oily food having the above functions imparted thereto can be produced by a convenient method.
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TOOTHBRUSH WITH DENTAL FLOSS AND TOOTHPASTE

(WO2006063423) 22.06.2006 A45D 44/00 GOMES, Antonio Carlos
Utility model patent for a pocket toothbrush which is composed by a part that serves as cap for the components, figure 2, that also is placed at the base of the body of the brush, as shown in figure 3;on the body of the brush, figure 4, are attached a toothpaste tube, figure 5, and a detachable compartment for dental floss, figure 7. These attachments can be better understood on figures 6 and 8; the fully assembled brush can be seen on figure 1.
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APPARATUS AND METHOD FOR BOOSTING SOUND IN A DENTA-MANDIBULAR SOUND-TRANSMITTING ENTERTAINMENT TOOTHBRUSH

(WO2006062778) 15.06.2006 G06F 17/00 HASBRO, INC.
A device and method for transmitting sound waves between a signal source and a user's ears, wherein the sound waves bypass the air. The sound waves are conducted by the user's teeth and bones to the user's ears, where they are perceived as sound. Sound-transmitting toothbrushes and the like are described to transmit and/ or conduct sound to the user's ear, while the user is brushing his or her teeth. The toothbrush head (100) and a signal source (108/604) are configured to produce sound waves for transmission through the toothbrush head (100) to the user's mouth, and a tension controller is configured to control the volume of the sound waves based on the pressure applied by the toothbrush head. The signal source (10/604) may produce sound w...
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SIGNAL PEPTIDES, NUCLEIC ACID MOLECULES AND METHODS OF TREATMENT

(WO2006060903) 15.06.2006 A61K 38/10 KANE BIOTECH INC.
The present invention provides isolated polypeptides capable of inhibiting S. mutans genetic competence and S. mutans biofilm formation. The present invention further provides peptide analogs of S. mutans competence stimulating peptides, compositions thereof, and uses thereof for inhibiting biofilm formation in streptococci and for the treatment and prevention of conditions caused by dental plaque associated streptococci.
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TOOTHBRUSH WITH TOOTHPASTE FOR SINGLE USE

(WO2006060887) 15.06.2006 A46B 9/04 ALEKSANDROV, Ivailo
When a person is eating food sticks to the teeth which cannot be removed by saliva. Drinking coffee and smoking results in teeth color changing. Toothbrush with toothpaste for single use eliminates the residues of food, coffee and cigarettes. It is compact and light because it joins both toothbrush and paste in one unit. It consists of 4 elements that make it easy for use. It could be used everywhere at any time. Toothbrush with toothpaste for single use consists of a toothbrush (1) that could be of different design and size, with artificial or natural hairs, with toothpaste (2) on them. The quantity of toothpaste is enough for single teeth brushing. The plastic cap (3) covers tightly the hairs and the toothpaste between them. The vacuuming...
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ORAL CARE COMPOSITION COMPRISING A PHENOLIC COMPOUND AND ANTIOXIDANT VITAMINS AND VITAMIN DERIVATIVES

(WO2006060145) 08.06.2006 A61Q 11/00 COLGATE-PALMOLIVE COMPANY
An oral care composition comprises an antibacterial phenolic compound and a vitamin or vitamin derivative component comprising one to a plurality of antioxidant vitamin or vitamin derivatives. In one embodiment the vitamin or vitamin derivative component comprises vitamin E and vitamin E acetate and optionally one or more additional vitamin or vitamin derivatives. In another embodiment the vitamin or vitamin derivative component comprises an antioxidant vitamin or vitamin derivative and a source of vitamin B5. A method of oral care comprises applying a composition as described above to an oral surface of a subject.
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PROCESS FOR PRODUCING FAT COMPOSITION REDUCED IN TRANS ACID CONTENT AND PROCESSED FAT PRODUCT CONTAINING THE FAT COMPOSITION

(WO2006059592) 08.06.2006 A23D 9/02 The Nisshin OilliO Group, Ltd.
A process for producing a fat composition which comprises: (a) the step of mixing a fat (A) comprising triglycerides in which fatty acids having 14 or less carbon atoms account for 50-100 mass% of all constituent fatty acids with a fat (B) comprising triglycerides in which fatty acids having 16-24 carbon atoms account for 80-100 mass% of all constituent fatty acids; (b) the step of subjecting the resultant fat mixture to random transesterification with the aid of an enzyme which does not have position specificity; and (c) the step of obtaining the target fat composition containing no trans acids. The fat composition, which contains no trans acids, has satisfactory plasticity and gives a satisfactory feeling upon melting in the mouth. Also p...
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BRUXISM EVALUATION SHEET

(WO2006059587) 08.06.2006 A61C 19/00 Rocky Mountain Morita Corporation
In order to establish a convenient evaluation means for employing bruxism in daily clinical diagnosis, it is intended to develop an apparatus whereby the interior of the oral cavity can be observed and occlusion patterns in sleep bruxism, which cannot be evaluated on an occludator, can be examined and so on. Namely, a bruxism evaluation sheet having a layer comprising an aqueous solution composition containing a dye and a thermosetting resin in an organic solvent formed on a base sheet made of a thermoplastic resin; and a method of producing a convenient bruxism evaluation apparatus which comprises heating the bruxism evaluation sheet as described above, vacuum pressing it into a model and then molding.
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COMPOSITIONS FOR THE ACUTE AND/OR LONG TERM TREATMENT OF PERIODONTAL DISEASES

(WO2006059196) 08.06.2006 A61K 31/198 EUROPEAN NATURAL PRODUCTS
Composition comprising a mixture of radix polygoni multiflori, Fructus Corni, cuscuta japonica, rehmannia glutinosa, licorice, asparagine, Derla andrographis and a composition comprising a mixture of Salvida persica, achyranthes aspera, spilanthes acmela, clove, picus Bengalensis, acacia nilotioca resen, eucalyptus, mint, green tea, bamboo silica for the acute and/or long term treatment of of microbial infections, in particular of oral pathogenic micro-organisms, in particular dental caries, periodontosis, gingivitis, gum disease, gum bleeding and/or plaque reduction.
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KIT FOR DENTAL CLEANING

(WO2006059193) 08.06.2006 A45D 44/18 COSTA, Sergio
A kit (1) for dental cleaning, comprising a toothpaste dispenser (2), provided with at least one opening (3) for dispensing toothpaste and with at least one hollow receptacle (4) arranged proximate to the opening, and at least one toothbrush (5) provided with a handle (6) for supporting a bristly head (7); the toothbrush (5) is suitable to be arranged so that the head (7) is protected at the receptacle (4) and so that a portion of the handle (6) faces the opening (3) in order to close it.
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CONNECTING ELEMENT FOR SHEET PILES

(WO2006058761) 08.06.2006 E02D 5/08 PILEPRO LLC
The invention relates to a connecting element for sheet piles, comprising a central strip (14) and two hook-type strips (16, 18) which extend therefrom and jointly form a claw-type strip (12) that has a C-shaped cross-section. The ends of the hook-type strips (16, 18) point towards each other and delimit a mouth (20) with the open ends thereof while the extended center lines (26, 28) of the ends of the hook-type strips (16, 18) intersect outside the open mouth (20). The inventive connecting element further comprises at least one connecting strip (30) which protrudes from the claw-type strip (12) and is provided with a straight neck-type strip (32) and a head-type strip (34) that has an oval cross-section. The main axis (38) of the head-type...
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COMPOSITIONS AND METHODS FOR WHITENING, MINERALIZING AND/OR FLUORIDATING CALCIFIED TISSUES

(WO2006057857) 01.06.2006 A61K 8/22 AMERICAN DENTAL ASSOCIATION FOUNDATION
Kits and methods that combine whitening/stain removal of teeth with remineralization are disclosed. These kits advantageously comprise separate compositions comprising a soluble calcium salt, a soluble orthophosphate salt, and a soluble peroxide, in order to optimize the stability of these components for storage and/or the activity of these components upon use. The active ingredients may also be separated in a solid composition (e.g., a powder) or in a stable dispersion comprising a non-aqueous dispersion medium.
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COMPOSITIONS AND METHODS FOR WHITENING, MINERALIZING AND/OR FLUORIDATING CALCIFIED TISSUES

(WO2006057727) 01.06.2006 A61K 8/21 AMERICAN DENTAL ASSOCIATION FOUNDATION
Kits and methods that combine whitening/stain removal of teeth with remineralization are disclosed. These kits advantageously comprise separate compositions comprising a soluble calcium salt, a soluble orthophosphate salt, and a soluble peroxide, in order to optimize the stability of these components for stor ge and/or the activity of these components upon use. The active ingredients may also be separated in a solid composition (e.g., a powder) or in a stable dispersion comprising a no -aqueous dispersion medium.
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COMPOSITION FOR DENTAL IMPRESSION TREATMENT MATERIALAND PREPARATION THEREOF

(WO2006057535) 01.06.2006 A61K 6/02 FERTON HOLDING S.A.
The present invention relates to a composition for dental impression treatment material and preparation thereof for the purpose of obtaining the superior impression in restoration treatment for dental prosthesis, and for the gingival retraction from the teeth, gingival oozing inhibition and stanching. The composition preferably comprises 67.70 to 71.85% by weight of kaolin clay, 16.05 to 20.00% by weight of distilled water, 10.83 to 11.50% by weight of aluminum chloride hexahydrate, 0.14 to 1.02% by weight of starch powder, 0.42 to 0.43% by weight of silicone oil, 0.03% by weight of coloring agent.
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A DENTAL FLOSSING DEVICE

(WO2006056867) 01.06.2006 A61C 15/04 SPEEDIE, Robert, Barry
The invention provides a dental flossing device of the kind driven by a prime mover. The mover is connected through a drive shaft to drive means adapted to impart oscillations to a forked floss support. The device includes a floss locator. The locator can be held against the teeth of a person using the flosser to steady the device and assist in controlled positioning of the device during use. The improved control for positioning of the oscillating floss assists in focussed cleaning between teeth and can deter against gum damage from misdirected flossing. The forked support is movable between a first position, wherein the floss is to one side of the support, and a second position, wherein the floss is to the other side. This adjustment of th...
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SKIN EXFOLIATING TOOL AND KIT

(WO2006056295) 01.06.2006 A47K 7/02 UNILEVER PLC
A skin exfoliating tool and kit is provided wherein the tool includes an applicator wand and a drying tray. The wand features a gripping handle, a platform projecting circumferentially outward from the handle and a pliable pad attached to the platform. The wand nests in the drying tray, the latter being formed with a cavity for receiving the pad, the cavity being defined by a floor and an open mouth. The tray has at least one drainage orifice adjacent the floor. The kit incorporates the exfoliating tool in combination with a skin exfoliating composition that is formulated with abrasive particles in a carrier vehicle.
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TRANSLUCENT VENEERING FOR A DENTAL PROSTHESIS FORMED BY A PRESS TO METAL PROCESS

(WO2006055800) 26.05.2006 A61C 13/083 DENTSPLY INTERNATIONAL INC.
A dental prosthesis, typically formed in a press to metal process, includes application of a porcelain composition sufficient to form a veneer on a dental prosthesis supporting metal structure, the composition having an integrated tooth-like translucency providing an aesthetic appearance. The composition is formed of a dentin frit and an enamel frit, typically sintered into a desired ingot shape including an amount of composition sufficient to veneer the prosthesis. The porcelain composition is a component of a kit that includes opaquers, other porcelains and stains useful in finishing to provide an aesthetic prosthesis.
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WAX-LIKE POLYMERIZABLE DENTAL MATERIAL

(WO2006053237) 18.05.2006 A61K 6/083 DENTSPLY INTERNATIONAL INC.
The invention provides a low polymerization shrinkage dental composition and a polymerizable dental material selected from the group consisting of wax-like dental material that undergoes ring open polymerization. The dental composition is useful as restorative material and for making artificial teeth, dentures, restoratives, crowns and bridges of high strength dental polymeric material.
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DENTAL WHITENING SYSTEMS COMPRISING TRANSITION METAL SALT ACTIVATOR

(WO2006053207) 18.05.2006 A61K 8/19 DISCUS DENTAL IMPRESSIONS, INC
A system and method for tooth whitening are disclosed wherein at least one peroxide-containing gel and at least one transition metal compound- containing gel, particularly at least one lower atomic number transition metal compound, more particularly at least a ferrous compound including gluconate, sulfate, nitrate, acetate or mixtures thereof, are applied to a patient's mouth. Gelling agent is also included. The activation of the peroxide whitens the patient's teeth. The system may be used with or without the application of light. The system further provides an additional gel including a sensitivity reduction compound including potassium nitrate, sodium nitrate or mixtures thereof for possible sensitivity treatment if needed.
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POST-FOAMING DENTAL MOUSSE AND METHODS UTILIZING THE SAME

(WO2006052476) 18.05.2006 A61Q 11/00 COLGATE-PALMOLIVE COMPANY
A post foaming oral care mousse is provided by the invention. The mousse includes at least a dentifrice composition and a compressed liquid propellant having a boiling point less than -10C. The liquid propellant is blended into the mousse as an emulsion, and the emulsion is adapted to be dispensed from a container as a gel that foams after a time delay. The mousse has a viscosity of less than 30,000 centipoise when measured prior to the addition of the propellant. Preferably, the mousse expands at least 100 vol % in less than 5 seconds upon exposure to atmospheric pressure.
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ULTRASONIC MOUTH CLEANING DEVICE

(WO2006052040) 18.05.2006 A61C 17/20 KUM, Kyong Won
An ultrasonic mouth cleaning device comprising a body; an ultrasonic generator included in the body; a vibrator for receiving a signal from the ultrasonic generator and generating ultrasonic waves; an ultrasonic emitter formed at one end portion of the body for emitting the ultrasonic waves into the inside of a mouth; and a connecting member for transferring the ultrasonic waves generated from the vibrator to the ultrasonic emitter is provided. The various shapes of the ultrasonic emitter are provided to make the ultrasonic emission three-dimensional and to make the agitation of cleaning liquid vigorous. Also, the protection means which prevent the emitter from directly contacting the mouth avoid the user's possible injury.
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DENTAL GLASS COMPOSITION

(WO2006050829) 18.05.2006 A61K 6/02 DENTSPLY DE TREY GMBH
An aluminosilicate glass composition comprising: (a) 10-35 % by weight of silica; (b) 10-35 % by weight of alumina; (c) 3-30 % by weight of zinc oxide; (d) 4-30 % by weight P205; and (e) 3-25 % by weight of fluoride which contains at most 3 % by weight of alkaline metals calculated as M20, wherein M is Li, Na, and/or K, and wherein the weight ratio of the sum of zinc oxide and fluoride to P205 of from 0.8 to to 3.0.
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TOOTHPASTE COMPOSITION

(WO2006050777) 18.05.2006 A61K 8/27 UNILEVER N.V.
Toothpaste comprising a first phase and a second phase which are stored in contact with one another, the first phase comprising calcium carbonate as abrasive and an alkali-metal citrate salt, the second phase comprising water and a zinc salt.
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MULTI-CHAMBER APPLICATOR

(WO2006049615) 11.05.2006 B67D 5/52 TSAUR, Garry
A compact disposable single-dose applicator that may be used to apply one or more substances such as adhesives and dental compounds. The mufti-chamber applicator comprises of a container (1), a compression means (2), and an applicator (3). The container comprises one or more chambers (4), (5) with a passage (12) positioned between the chambers (4), (5) that will accept an applicator (3) inserted into the passage (12). Each chamber (4), (5) has one or more fluid flow paths (13), (14) leading from the chamber (4), (5) to the passage (12). The compression means (2) comprises of one or more elongated protrusions (15), (16) that are connected at their base to a compression plate (17). As the compression means (2) is urged into the chambers (4), ...
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TOOTHPASTE COMPOSITION COMPRISING ESSENTIAL OIL

(WO2006049367) 11.05.2006 A61Q 11/00 KIM, Jong Cheol
Disclosed is a toothpaste composition including an essential oil in the base of conventional toothpaste compositions to have strong effect on the removal of mouth odors and oral bacteria. In the present invention, the essential oil is selected from the group consisting of peppermint oil, lemon oil, tea tree oil, and combinations thereof, and when used, the peppermint oil is in an amount of 0.50-0.85wt%, the lemon oil in an amount of 0.20-0.65wt%, and the tea tree oil in an amount of 0.07-0.25wt% based on the total weight of the composition. The toothpaste composition of the present invention has excellent effects on the removal of mouth odors and the treatment of periodontal diseases, in addition to the basic function of toothpastes, such a...
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REMEDY FOR NEUROPATHIC PAIN

(WO2006049312) 11.05.2006 A61K 45/00 JAPAN SCIENCE AND TECHNOLOGY AGENCY
It is intended to provide a remedy for neuropathic pain capable of exhibiting an excellent therapeutic effect on neuropathic pain which is an intractable disease. More specifically speaking, a remedy for neuropathic pain which contains an opioid receptor antagonist (in particular, naloxone, naltrexone, naloxonazine, naltrindole, etc.) as the active ingredient; a medicinal composition for treating neuropathic pain which contains an opioid receptor antagonist as the active ingredient; a method of treating neuropathic pain by using an opioid receptor antagonist, and so on.
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DEVICE FOR MEASURING DEPTH OF GINGIVAL SULCUS

(WO2006046831) 04.05.2006 A61C 19/04 LEE, Yo Seob
Disclosed is a device for measuring a depth of a gingival sulcus, including a body unit, a fixed plate having one end fixed in the body unit and the other end exposed to the outside of the body unit, a movable plate having an end pivotably coupled to the fixed plate and the other end which is movable, a pin unit having a depth indication unit capable of indicating a depth inserted into a gingival sulcus while a part thereof is inserted into the gingival sulcus, the pin unit being coupled to an edge of the other end of the movable plate, and an elastic member for making the movable plate be elastically biased with respect to the fixed plate, so that the movable plate is pivoted with respect to the fixed plate by an amount corresponding to a ...
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BOTTLE CAP

(WO2006046730) 04.05.2006 B65D 51/28 THE COCA-COLA COMPANY
A bottle cap comprises an outer cylinder (1) attached to the mouth portion of a bottle, and an inner cylinder (2) connected to the outer cylinder (1) and suspended in a cavity within the mouth portion. The inner cylinder (2) includes a barrier (3) at its one end, which can be displaced toward the bottom of the bottle, and a thin sheet (4) at the other end, thereby forming a closed chamber (M) for storing an ingredient to be added to the liquid content in the bottle. The barrier (3) has a perforator (5) which can be displaced to open the thin sheet (4), thereby allowing the ingredient in the chamber (M) to fall into the bottle.
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BOTTLE CAP WITH A STORAGE CHAMBER

(WO2006046721) 04.05.2006 B65D 51/28 THE COCA-COLA COMPANY
A cap with a storage chamber for storing an ingredient to be added to a liquid content within a container (10) includes a base (110) to be attached to a mouth portion of the container, which has a spout (113) for allowing passage of the liquid content out of the container (10). A lid (120) is fastened by screwing to the base (110) and includes the storage chamber (124) and a thin sheet (123) for sealing it. The base (110) has an annular part (114a) fixed to an inner wall of the spout, for maintaining a channel communicating with an interior space of the container (10). The base (110) has a slanted blade (114b) which comes into contact with the thin sheet (123) as the lid (120) is moved downwards, for cutting the thin sheet and allowing the ...
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NOSE MASK

(WO2006045251) 04.05.2006 A62B 23/06 LAM, Philip, Yung Tak
The present invention relates to a nose mask, including shell, lower casing, filter sheet, hollow air passage stiff tube, chemical solid, chemical liquid. Said shell is mounted in the naris of the user, whose periphery is a dished vane, which can make the nose mask fix at the position in the naris of the user, and is provided with the space to hold the nose excreta of the user. The shell is also provided with an orifice, which is connected with the air passage stiff tube for inhaling or exhaling air. The lower part the air passage stiff tube is a bell mouth, the lower edge of the shell and the upper edge of the lower casing are provided with the interface for making them joint together so as to form an inner space. A filter sheet is fixed a...
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FLAVONOID COMPOSITION FOR TREATING ORAL DISEASES

(WO2006045056) 27.04.2006 A61K 31/35 UNIGEN PHARMACEUTICALS, INC.
The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compounds --Free-B-Ring flavonoids and flavans-- for use in the prevention and treatment of diseases and conditions associated with mouth, gums and teeth. This composition of matter simultaneously inhibits cyclooxygenase (COX) and lipoxygenase (LOX) enzymatic activity and reduces cytokine production at the mRNA level in normal, aged and damaged periodontal cells and tissues. This invention further provides a method for the prevention and treatment of diseases and conditions of the mouth, gums and teeth. The method for preventing and treating diseases and conditions of the mouth, teeth and gums is comprised of administering to a hos...
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DENTAL SELF-ETCHING COMPOSITION AND METHOD OF USE

(WO2006045034) 27.04.2006 A61K 6/00 PENTRON CLINICAL TECHNOLOGIES, LLC
A self-etching primer composition and method for etching and treating a tooth surface prior to restoration. The self-etching primer composition contains DOPA. In practice, the composition is applied to the tooth surface and not subsequently washed prior to application of an adhesive or other restorative material.
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SYSTEMS, METHODS AND COMPOSITIONS FOR PROMOTING ORAL HYGIENE

(WO2006044574) 27.04.2006 A61C 15/00 PURI, Suraj
Systems, methods and compositions for promoting oral hygiene are described. According to the present invention, oral hygiene is promoted by the use of a charged solution on the mouth tissue. Inventive methods for producing the cleaning solution includes charging a solution, which contains at least a solute selected to promote cleaning of tissue present in mouth. As a result of charging, at least a portion of the solute is present as clusters in the charged solution. Inventive systems for producing the cleaning solution includes: (1) a charging chamber for holding a solution, which contains at least a solute selected to promote oral hygiene; and (2) a first acoustic energy source capable of vibrating said solution in said charging chamber to...
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DENTAL TREATMENT TRAY COMPRISING A PLASTICIZED RESIN FOR IMPROVED MOLDABILITY AND CONFORMABILITY

(WO2006044312) 27.04.2006 A61C 5/00 ULTRADENT PRODUCTS, INC.
A dental treatment tray (100) used to provide a desired treatment is injection molded from a composition that includes at least one thermoplastic resin and at least plasticizer. The plasticized thermoplastic resin permits the dental treatment tray (100) to be injection molded even while having a wall thickness less than about 0.015 inch. The plasticizer increases the melt flow index of the thermoplastic resin while in a molten state, which facilitates complete filling of the mold cavity by the thermoplastic resin. The plasticizer also softens the thermoplastic polymer while in a solidified state in order to yield a dental tray (100) that is even more flexible and comfortable for the user to wear.
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TEETH-POLISHING MOUTH AND TOOTH CARE AND CLEANING SUBSTANCES THAT REDUCE BAD BREATH

(WO2006042582) 27.04.2006 A61Q 1/00 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
Disclosed are mouth and tooth care and cleaning substances which polish and clean the tooth surface well without having an overly abrasive effect while acting against bad breath. Said substances contain at least 10 percent by weight of sorbit and/or glycerin and/or 1,2-propylene glycol as well as at least 0.25 percent by weight of at least one bioactive glass.
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CARBONATED PROTEIN DRINK AND METHOD OF MAKING

(WO2006042222) 20.04.2006 A23C 21/00 NEXT PROTEINS, INC.
An improved carbonated protein beverage/drink composition which provides a relatively high protein content, ranging from about 2 % by weight to about 15 % by weight, while simultaneously employing a carbonation concentration between about 0.1 volumes of carbonation (per volume of liquid drink solution or liquid drink suspension) to about 4 volumes of carbonation. Preferably the protein is whey protein. The carbonated protein beverage has been heat treated to inactivate microbes in the presence of the carbonation which is used to provide taste and mouth feel for the drink. Typically, the treatment for microbe inactivation is carried out in the individual package used for storage and handling of the carbonated protein drink.
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TOOTHPICK DEVICE

(WO2006041637) 20.04.2006 A61C 15/00 PETERS, Cassie, Jr.
A toothpick device (10) for cleaning teeth includes a toothpick (12). The toothpick (12) is comprised of two separable portions (22, 24) and has at least one pointed end (14). A length of dental floss (16) is provided with each end of the dental floss (16) being secured to one of the two portions (22, 24) of the toothpick (12). The dental floss (16) is wound for storage between said two portions (22, 24) whereby separating the two portions (22, 24) unwinds the dental floss (16) for use.
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SYSTEMS AND METHODS FOR UTILIZING ULTRASONIC ENERGY TO ACTIVATE TOOTH WHITENING SUBSTANCES

(WO2006041432) 20.04.2006 A61C 5/00 CAO GROUP, INC.
While various structures, compounds and methods Tooth whitening may be accelerated and intensified by use of ultrasonic energy. Although ultrasonic energy does nothing to directly enhance whitening (i.e., it has no direct effect on stains, tooth enamel, or peroxides), ultrasonic energy may be utilized to accelerate and intensify chemical reactions between a peroxide and another dental bleach constituent, consequently accelerating and enhancing the release of oxygen ions from the peroxide, which in turn accelerates and enhances the whitening of teeth.
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DENTAL ALLOY WITH A HIGH GOLD CONTENT THAT IS DEVOID OF PALLADIUM AND COPPER

(WO2006040145) 20.04.2006 C22C 5/02 DEGUDENT GMBH
The invention relates to a dental alloy with a high gold content that is devoid of palladium and copper. To achieve a high mechanical stability, the dental alloy consists of between 75 and 95 wt. % Au, between 5 and 20 wt. % Pt, between 0.5 and 3.5 wt. % Zn and/or Sn and/or In, between 0.1 and 0.8 wt. % of an element of a group I, in addition to a single particle refiner of a group II. The weight fraction of the element of group I is between 2 and 6 times that of the single particle refiner of group II, and one element of the group I is represented by Nb or Ta or Ti or V and the particle refiner of group II is represented by Ir or Rh.
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STERILIZER FOR AND METHOD FOR STERILIZING DENTAL HANDPIECES

(WO2006039509) 13.04.2006 A61L 2/07 DENTSPLY INTERNATIONAL INC.
A sterilizer for a dental handpiece is provided. The sterilizer provides equalized distribution of steam to a plurality of handpieces, assured minimum lubrication delivery and pressurized exhaust handpiece maintenance adapters. There is also provided a swivel adapter for a fixed-back handpiece and a detergent tablet for the cleaning chamber. There is also provided oil and evaporable solvent solution for lubrication purposes; reservoir inlet specific pour spout; SCBI and steam strip holder; a water reservoir flush routine; and, a forced chamber drain cycle.
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SEALED, EDIBLE FILM STRIP PACKETS AND METHODS OF MAKING AND USING THEM

(WO2006039487) 13.04.2006 A23L 1/00 THE HERSHEY COMPANY
The invention provides, in one aspect, a method of making a confectionery packet or sachet formed with an edible film and enclosing a center composition. The packet or sachet can be designed to be placed in the mouth, where the film dissolves and the center composition is released. In preferred embodiments, the center composition comprises a sugar alcohol, such as xylitol, that creates a cooling sensation. Many other flavors and/or colors or sensates can also be used in the center composition, and some embodiments include breath-freshening, anti-bacterial, nutriceutical, or pharmaceutical compositions in the center composition. The invention also comprises the edible packets or sachets, especially those composed of film with a desired retai...
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GRATING ROLLER

(WO2006038857) 13.04.2006 B02C 4/30 GSTA LARSSONS MEKANISKA VERKSTAD AB
The invention concerns a grating roller (1) , espe- cially intended for grating potatoes and manioc roots. The grating roller is along its periphery provided with a plurality of axial grooves (2) for holding strip-shaped grater tools (3) , which are axially inserted into the grooves (2) . The grooves have an undercut with a width increasing radially inwards from the mouth of the grooves. Moreover the grooves are spaced apart by axial partitions (4) with a predetermined minimum wall width (bmin) , seen in the circumferential direction, and have a radial depth (D) . The grating roller is characterised in that the partitions have said predetermined minimum width (bmin) in a portion which is positioned less than 60% of the groove depth (D) from...
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STABILISED OXYGEN RELEASING COMPOSITION

(WO2006038802) 13.04.2006 A61K 8/22 NGEN PHARMACEUTICALS N.V.
The present invention relates to stabilised liquid oxygen releasing composition comprising a component (a) selected from the salts consisting of cations An+ and anions derived from halogen oxides according to the general formula [OmX]- wherein A is a metal selected from Groups 1 or 2 of the Periodic System of the Elements, X is a halogen atom, m = 1 - 4, n = 1 or 2, a component (b) selected from the group of oxygen donors, a component (c) selected from the group of oxygen donor stabilising agents and a component (d) selected from the group of liquid binders. The stabilised liquid oxygen releasing composition can be used in pharmaceutical compositions, cosmetic compositions and food applications, e.g. skin care products, dental care products...
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CLEANING INSTRUMENT FOR DENTAL AND ORAL HYGIENE

(WO2006038058) 13.04.2006 A46B 9/04 NAHUM, Sylvain-Victor
The invention concerns a cleaning instrument for dental and oral hygiene (3) consisting of an ergonomic handle (5) with or without an incorporated motor comprising at its front end a clip-on system (7) and at its rear end a hydraulic nozzle (17) and two induction electrical contacts (E); of a disposable brushing head (3) with dual cleaning surface (A) and (B), which consists of six bristle-covered cylinders of different diameters, two large ones with hard bristles (D), two medium-sized ones with medium bristles (8) and two small ones with soft bristles (9). The invention is characterized in that the brushing head (3) is removable and dispensable after use. The six bristle-covered cylinders (D) (8) (9) are aligned at different heights on the...
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TUBE PASTE SQUEEZER, ESPECIALLY TOOTHPASTE SQUEEZER

(WO2006035250) 06.04.2006 B65D 35/32 JUROS, Ivan
This invention, tube paste squeezer, especially toothpaste squeezer, is a simple, reliable and aesthetical solution of the problem. It is characterized by combining original construction interventions with simplicity in achieving the set goal: complete extrusion of the paste out of the tube and aesthetical appearance of the used tube.
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CARATENOID COMPOSITION AND METHOD FOR PREPARATION THEREOF

(WO2006034556) 06.04.2006 A23D 7/005 BOS, Michael, Ary
This invention relates to a carotenoid composition comprising the carotenoid as particles of size smaller than 100 nanometers in an oil medium and a method of preparing the composition by milling the carotenoid in an oil medium and therapeutic compositions containing the carotenoid.
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TEMPORARY COSMETIC DENTAL SURFACE COATING

(WO2006034493) 30.03.2006 A61K 8/97 HURWITZ, Mami, Markell
A temporary cosmetic dental coating has a transparent resin matrix containing embedded glass microspheres. The refractive index of the microspheres is at least 0.03 greater than the refractive index of the transparent resin matrix. Incoming light is reflected back in the same direction as it was emanated, providing a lustrous dental coating that is cosmetically appealing and covers dental defects and discoloration. The transparent resin matrix with glass microspheres is formed by mixing together a methacrylate based liquid monomer of methyl methacrylate or BIS-GMA and glass microspheres coated with activators/ catalysts. The user applies the mixed composition to the teeth to form a temporary cosmetic dental coating, which is readily removed...
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SOIL CLEANING METHOD AND APPARATUS

(WO2006032845) 30.03.2006 B08B 3/10 UNIVERSITY OF SHEFFIELD
A soil/sand cleaning reactor (10) comprises one or two cylinders (18, 20) each having a jet (28) directed towards each other or a target. The jets are immersed in water (14) in a tank (12) and a pump (42) is operated in two modes of operation. In one, both cylinders are pumped simultaneously so that streams issuing from the jets (28) collide and sand/soil particles entrained in the flow are scrubbed. In the second mode of operation the cylinders are pumped alternately. Flow from cylinder enters the other, cavitation occurring on exit of the flow from each jet and implosion occurring in the high pressure region of the other jet, such cavitation and implosion effecting scrubbing of the sand/soil particles. Alternatively, there is just one cyl...
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LOZENGES BASED ON MUCOLYTIC DRUGS FOR INFLAMMATORY DISEASES OF THE MOUTH AND PHARYNX

(WO2006032364) 30.03.2006 A61K 36/00 MARIA CLEMENTINE MARTIN KLOSTERFRAU VERTRIEBSGESELLSCHAFT MBH
The invention relates to a pharmaceutical composition in solid dosage form, suitable for topical treatment of, in particular, painful, inflammatory diseases of the mouth and pharynx, whereby the pharmaceutical composition is a combination of pharmaceutically-effective amounts of (a) at least one mucolytic drug and/or extracts of, in particular, Iceland moss (Lichen islandicus) and/or Marsh mallow (Althaea officinalis L.) and (b) at least one local anaesthetic suitable for topical application. The solid dosage form is preferably a lozenge, in particular made from hard caramel.
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CLEAR VIEW DENTAL EXPLORER

(WO2006031242) 23.03.2006 A61C 19/04 HOEFFLEUR, Jacques, D.D.S.
The Clear View Dental Egplorer acts like a standard clinical dental explorer, to detect tooth-borne caries and other anomalies during an oral dental exam. However, in addition to this function, the Clear View Dental Explorer also originates an air nozzle that blows saliva, blqod, or plaque away from the area of clinical observation by directing a forceful stream of air to the tip, or pointed end, of the explorer instrument area.
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PERMUCOSAL COMPOSITION AND METHOD OF IMPROVING PERMUCOSAL ABSORPTION

(WO2006030730) 23.03.2006 A61K 38/00 OTSUKA PHARMACEUTICAL CO., LTD.
A permucosal composition designed so that a pharmacologically active peptide or protein is efficiently absorbed through a mucosa such as pulmonary mucosa, nasal mucosa, mouth mucosa, vaginal mucosa, ocular mucosa, gastric mucosa, or the mucosa of digestive tract. The permucosal composition is prepared by incorporating the following ingredients (i) and (ii): (i) at least one member selected from the group consisting of physiologically active peptides and proteins; and (ii) at least one member selected from the group consisting of chitosanoligosaccharides having a degree of polymerization of 2-20, derivatives thereof, glucosamine, and salts of these.
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MULTIBLADE FAN

(WO2006030542) 23.03.2006 F04D 29/30 MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.
A multiblade fan, comprising a volute casing (21) having a bell mouth-like orifice (22) formed on one side thereof and having a suction port (23) and a discharge port (24), an impeller (25) having, in the casing (21), a plurality of blades (29) pivotally supported, at both axial ends, on a main plate (27) and a side plate (28), and a motor (26) driving the impeller (25). The blades (29) are formed so that the shape of the cross section thereof vertical to the rotating axis is specified in a specified axial length, and a mainstream flows along the rear surface of the blades (29).
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COMPOSITION FOR INHIBITING OR PREVENTING THE FORMATION OF A BIOFILM

(WO2006029893) 23.03.2006 A61K 45/06 OYSTERSHELL NV
The present invention provides the use of a compound selected from the group comprising an anthraquinone and a naphtoquinone, stereoisomeric forms, racemic mixtures, metabolites, esters or salts thereof, or mixtures thereof, and/or of at least one plant extract or active fraction thereof comprising said compound for preventing and/or inhibiting biofilm formation. The present invention further relates to compositions for preventing and/or inhibiting the formation of a biofilm, oral health products and a method for preventing and/or inhibiting biofilm formation.
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A UTILITY BELT

(WO2006028389) 16.03.2006 A45F 5/00 GRILLSLINGER INTERNATIONAL LIMITED
A utility belt for use in supporting and retaining cooking utensils and cooking accessories. The utility belt (10) has a waistband (11). At least one holster (16) is coupled to the waistband (11). A removable tool insert (22) is located in the holster (16). The tool insert (22) is configured to receive a part of a cooking implement or tool (23, 25) to retain the cooking implement or tool. In a preferred form of the invention there are a plurality of holsters (16) at least some of which have a removal insert (22). The holster (16) can be attached to an upper pocket (14). The insert (22) has an uppermost mouth opening (28) into an otherwise enclosed space, which is configured to receive the part of the cooking tool or implement (23, 25) and i...
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DENTAL PLAQUE DETECTION SYSTEM AND DENTAL PLAQUE DETECTION METHOD

(WO2006028099) 16.03.2006 A61C 19/04 LION CORPORATION
It is intended to provide a dental plaque detection system and a dental plaque detection method whereby dental plaque can be detected at a high accuracy while relieving the staining in parts (interdental space, gingiva, etc.) other than dental plaque. This dental plaque detection system comprises a dental plaque-staining agent containing at least one member selected from among a yellow pigment originating in red koji mold, a turmeric extract and curcumin and a light-emission unit (10) emitting light of from 250 to 500 nm in wavelength toward a subject (40) in the oral cavity having the dental plaque-staining agent attached thereto. The dental plaque detection method comprises attaching the dental plaque-staining agent having the composition...
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METHOD USED TO POSITION TEETH IN A DENTAL ARTICULATOR AND RELEVANT DENTAL ARTICULATOR

(WO2006027815) 16.03.2006 A61C 11/00 GIANNETTI, Luigi
A plurality of teeth is positioned on a mandibular model (4) by blocking a mounting plate (23) in a determined reference position that corresponds to the height of teeth of the mandibular model (4), inserting a plurality of pin elements (29) through the mounting plate (23) and in a mandibular crest (30) of the mandibular model (4) and a maxillary crest (34) of a maxillary model (10) to identify on the mounting plate (23) two teeth distribution lines (32, 35) on the mandibular and maxillary crests (30, 34) and positioning the teeth between the mandibular crest (30) and a median distribution line (36) obtained by interpolating the two distribution lines (32, 35).
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ORAL DENTAL AND DENTAL PROSTHESIS CARE PRODUCT CONTAINING SUBSTANCES INHIBITING THE FORMATION OF PLAQUE

(WO2006027248) 16.03.2006 A61K 8/97 HENKEL KOMMANDITGESELLSCHAFT AKTIEN
The invention relates to oral and dental care products containing substances which inhibit the formation of bacterial biofilms and the use thereof for the prevention and removal of biofilms of bacterial origin.
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POLYMER RESIN COMPOSITION

(WO2006027139) 16.03.2006 C09J 155/00 HANSE CHEMIE AG
The invention relates to a polymer resin composition comprising (a) at least one type of resin selected from a group of vinyl-ester and unsaturated polyester resins, acrylates and methacrylates, (b) at least one type of copolymer which contains groups reactive with respect to resins and whose glass transition temperature Tg is equal to less than 20 C and (c) nanoparticles whose mean-size dmax measured by means of small-angle neutron scattering (SANS) ranges from 5 to 150 nm. The inventive composition makes it possible to produce composite materials, coatings, filling compounds, adhesives and dental materials provided with improved mechanical properties, in particular with increased impact resistance.
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FLOATING START INSTALLATION FOR A SPACE PROJECTILE

(WO2006026958) 16.03.2006 B64G 5/00 GERSTENHAUER, Christoph
According to the invention, an extremely long tube, which is open at the top and stabilised in water by floats or weights, is filled with water in its lower section and connected to another water tank, whose upper section is filled with air. The propellant carriage is ejected downwards into the water upon ignition, said water cooling the tube wall. The space projectile is installed together with the upper stage of a rocket in a carriage, which is provided with a thrust plate, above the propellant carriage and is accelerated in a uniform manner to the mouth of the tube when the propellant is ignited. Extremely high speeds can be achieved as a result of the length of the tube and the rapid acceleration. The entire tube system is controlled by...
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GOLD OR SILVER PARTICLES WITH PARAMAGNETISM, AND COMPOSITION CONATINING THEREOF

(WO2006025637) 09.03.2006 A61K 8/19 NANO PLASMA CENTER CO., LTD.
The present invention is related to gold or silver powder characterized by having paramagnetism. In more detail, contrary to the conventional gold or silver powder known to be a diamagnetic material having magnetism in the opposite direction to that of the magnetic field in the external magnetic field, the gold or silver powder according to the present invention is characterized by being a paramagnetic gold or silver powder having magnetism in the same direction as that of the external magnetic field, i.e., in the positive direction, in all temperature ranges, which is further characterized by having saturated magnetic moment with the external magnetic field, H, of 2,000 to 8,000 Oe. The paramagnetic gold or silver powder according to the p...
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EVACUABLE STORAGE BAG HAVING RESEALABLE MEANS ACTIVATED BY SLIDER

(WO2006024976) 09.03.2006 B65D 33/25 ILLINOIS TOOL WORKS INC.
A storage bag comprises: first and second panels(4a,4b)joined or connected on three sides and having a mouth on a fourth side; a pair of zipper strips respectively joined to the first and second panels in the region of the mouth, each zipperr strip comprising respective upper and lower zipper profiles; resealable means (joined to at least one of the zipper strips in a region between the upper and lower zipper profiles; and a slider(10) that pushes the respective pairs of zipper profiles together and reseals the resealable means as the slider travels along the mouth of the bag. In one embodiment, the resealable means comprise a layer of adhesive material that adheres to the base web of the opposing zipper strip as the moving slider presses t...
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PERMANGANATE CONTAINING WHITENING COMPOSITIONS AND METHODS OF THEIR USE

(WO2006023904) 02.03.2006 A61C 5/00 MILLENNIUM DENTAL INTERNATIONAL INC.
In general, the invention provides a fast-acting, whitening composition containing permanganate. Particular alkali-metal or alkaline-earth metal salts of permanganate; hydrogen peroxide; or an alkali or alkaline-earth metal peroxide; and an acid.
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LOCKING CASE FOR A TOOTHBRUSH

(WO2006023641) 02.03.2006 E05B 69/00 BRIGHT, Aaron, L.
A locking storage case (20) for holding a toothbrush (22). As two parts of the case (26, 28) are slidably engaged with each other to form an enclosed cavity (20) holding the toothbrush (22), a combination lock (30), integrally and rigidly mounted to the parts of the case, becomes engaged for locking the case (20). A suction cup (72) is provided for hanging the locking case (20) from a smooth surface (48). A resealable plastic bag (78) is provided within the locking case (20) for sealing the toothbrush (22) from germs and moisture and contaminants, and the resealable bag (78) may have an antibacterial coating on its interior surface. A toothpaste tube (2.82) may be provided in the cavity, and the toothbrush (22) may have a removable head (2....
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SONOPHOTODYNAMIC THERAPY FOR DENTAL APPLICATIONS

(WO2006022970) 02.03.2006 A61N 5/06 ONDINE INTERNATIONAL LTD.
The present invention includes methods for killing microbes in an oral cavity or wound comprising: applying a photosensitizing composition to a locus or a wound (102); applying a fluid and sonic energy to the locus or wound (104); and irradiating the locus or wound with a light source at a wavelength absorbed by the photosensitizing composition so as to destroy microbes at the locus or wound (106). The present invention also include methods for killing microbes in an oral cavity or wound comprising: applying a photosensitizing composition to a locus or a wound (202); and applying sufficient sonic energy to the locus or wound in order to provide acoustic cavitation so as to destroy microbes at the locus or wound (204). The present invention ...
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TOOTH WHITENING COMPOSITIONS AND DELIVERY SYSTEMS THEREFOR

(WO2006022850) 02.03.2006 A61K 8/365 CADBURY ADAMS USA LLC
Stain-removing oral compositions, such as gum compositions are herein provided. The compositions include an orally acceptable carrier and a stain-removing anionic surfactant. The surfactant includes a fatty acid salt having at least one hydroxyl functionality. The fatty acid salt may be a salt of ricinoleic acid, and may be combined with a chelating agent and/or an abrasive. The chelating agent may be a polyphosphate and the abrasive may be a silica abrasive.
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TOOTH WHITENING COMPOSITIONS AND DELIVERY SYSTEMS THEREFOR

(WO2006022848) 02.03.2006 A61K 8/365 CADBURY ADAMS USA LLC
Stain-removing oral compositions, such as gum compositions, are herein provided. The gum compositions include a film-forming agent, such as a fatty acid salt, in combination with an abrasive and a chelating agent. The fatty acid salt may be a salt derived from a hydroxy fatty acid. The chelating agent may be a polyphosphate and the abrasive may be a silica abrasive.
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T-SHIRT STYLE BAG WITH REGISTERED ADVERTISING STRIP, APPARATUS AND METHOD FOR MAKING SAME

(WO2006022760) 02.03.2006 B65D 30/20 DANIELS, Mark, E.
Plastic shopping bags having upper and lower seams, at least one side gusset, an open bag mouth and upper bag handles has attached promotional ad strips. The strips include a central removable portion and a pair of remainder portions at either end of the strip that are sealed into the upper and lower seams. The ad strips are registered to the upper and lower bag seams so that whole numbers of the coupons, messages or promotions will fall within the removable portion of the strip. Perforations join the removable portion of the strip to the remainder portions. An apparatus for registering the ad strips to plastic shopping bags includes markers on the bags and on the ad strips, sensors to detect the markers, a controller to match the speed of ...
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DENTAL FILLING MATERIAL

(WO2006022747) 02.03.2006 A61K 6/00 PENTRON CLINICAL TECHNOLOGIES, LLC
A dental filling material comprising an inner core and outer layer of material disposed and surrounding the inner core, both the inner core and outer layer of material each containing a thermoplastic polymer. The thermoplastic polymer may be biodegradable. A bioactive substance may also be included in the filling material. The thermoplastic polymer acts as a matrix for the bioactive substance. The composition may include other polymeric resins, fillers, plasticizers and other additives typically used in dental materials. The filling material is used for the filing of root canals.
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OILY FOOD AND PROCESS FOR PRODUCING THE SAME

(WO2006022210) 02.03.2006 A23D 9/00 FUJI OIL COMPANY, LIMITED
[PROBLEMS] To develop an oily food, which can sustain favorable texture (an appropriate hardness in chewing and a high meltability in mouth) over a long period of time while lessening softening in chewing and chewy texture (long-lasting sticky feel in the oral cavity) increasing during storage and to which the above functions are imparted by a convenient process; and a process for producing the same. [MEANS FOR SOLVING PROBLEMS] In preparing an oily food, POP and SOO in the fat composition (wherein P represents palmitic acid; O represents oleic acid; and S represents a saturated fatty acid having 18 or more carbon atoms, provided that these fatty acids are attached to the 1-, 2- and 3-positions of triglyceride in this order) a...
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METHOD OF DETECTING BRAIN TUMOR, BRAIN TUMOR-DETECTING AGENT TO BE USED THEREIN AND MEDICINAL COMPOSITION

(WO2006022114) 02.03.2006 G01N 33/574 NIIGATA UNIVERSITY
It is intended to provide a method of detecting brain tumor whereby brain tumor can be surely detected at the early stage; a brain tumor-detecting agent to be used therein; and a medicinal composition for treating brain tumor. Detection of brain tumor based on the detection of an N-binding sugar chain A2G2F of a glycoprotein, which is specifically expressed in brain tumor, contributes to the early detection and treatment for brain tumor. Moreover, brain tumor can be surely detected at the early stage by using a lectin capable of binding specifically to the N-binding sugar chain A2G2F. A brain tumor-detecting agent having the lectin capable of binding specifically to the N-binding sugar chain A2G2F of the glycoprotein makes it possible to ea...
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ORAL CARE IMPLEMENT

(WO2006020698) 23.02.2006 A46B 9/04 COLGATE-PALMOLIVE COMPANY
An oral implement with a handle includes a head with a releasable material (e.g., an oral medicament) and a tissue cleanser for cleaning the soft tissues and removing odor-causing bacteria from the mouth. In one arrangement, the releasable material is disposed on the surface of the tissue cleanser. In one arragement, the releasable material is disposed behind the tissue cleanser. In one arragement, the releaseable material is incorporated in the composition of the tissue cleanser.
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TREATMENT DEVICES FOR PROVIDING ORAL TREATMENTS AND KITS AND METHODS THAT UTILIZE SUCH TREATMENT DEVICES

(WO2006020502) 23.02.2006 A61C 19/00 ULTRADENT PRODUCTS, INC.
Treatment devices (10) in the shape of a dental tray, strip or patch include a barrier layer (12) and a protective adhesive composition (24,26). Treatment kits include one or more treatment devices (10) and one or more treatment compositions (28) that are initially separate from the treatment devices (10). The treatment compositions (28) may be contained within a syringe (e.g., a unit dose syringe) for ease of delivery. The treatment composition (28) is dispensed from the syringe onto the barrier layer (12) and then placed over a person's teeth and/or gums. The protective adhesive composition (24,26), in combination with the barrier layer (12), at least partially confines the treatment composition (28) to a desired location within the perso...
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TOOTH WHITENING LENS WITH BITE PLATE

(WO2006020128) 23.02.2006 A61C 5/00 OSBORN, Joyce, A.
A teeth whitening device having a lens which fits against the teeth. The lens has a casing containing a plurality of light emitting diodes which project light into the lens. The lens filters the light to produce a 430 to 450 nanometer blue light which is projected onto the surface of the teeth. When carbamide peroxide is placed on the surface of the teeth the blue light will activate the peroxide to whiten the teeth several shades within one hour without heating or sensitizing the teeth. The lens has a bite plate which a user bites down on to keep the lens in position against the teeth, leaving the user's hands free. The device and method are safe enough for use outside the dental office.
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METHODS AND COMPOSITIONS FOR THE TREATMENT OF DISEASES CHARACTERIZED BY PATHOLOGICAL CALCIFICATION

(WO2006019844) 23.02.2006 A61K 31/00 NANOBAC LIFE SCIENCES
Methods and compositions are provided which contains preparations of calcium chelators, bisphosphonates, antibiotics, antimicrobial agents, cytostatic agents, calcium ATPase and pyrophosphatase pump inhibitors, calcium phosphate-crystal dissolving agents, agents effective against calcium phosphate-crystal nucleation and crystal growth, and/or a combination of supportive agents and which may be used for treating and or reducing pathological calcifications, the growth of Nanobacteriu and calcification-induced diseases including, but not limited to, Arteriosclerosis, Atherosclerosis, Coronary Heart Disease, Chronic Heart Failure, Valve Calcifications, Arterial Aneurysms, Calcific Aortic Stenosis, Transient Cerebral Ischemia, Stroke, Peripheral...
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INTEGRAL TOOTHBRUSH

(WO2006019289) 23.02.2006 A46B 11/00 SEDANO FLORES, Jorge
The invention relates to an integral toothbrush consisting of: a hollow head (1) comprising fixed and rotating bristles and a hole for dispensing toothpaste onto the bristles; a conical section (15) which is joined to the head by means of threading and which is equipped with a tubular extension (12) that is introduced into the head (1), said extension (12) comprising a perforation which corresponds positionally to that of the head, such that the toothpaste can only be dispensed when the two perforations are in line; a toothpaste container (18) which is connected to the lower part of the conical section (15) and which has a hollow knob (25) coupled to the lower end thereof, a threaded rod (26) being fixed to said hollow knob, passing through...
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TOOTH BRUSH

(WO2006018927) 23.02.2006 A61C 17/00 LION CORPORATION
A high quality tooth brush softly and comfortably touching to teeth and gums, capable of providing high brushing feeling and massaging feeling and excellent dental plaque removing force, suitable for curing or preventing serious or slight periodontal disease and gingivitis, enabling the extraction of bristles since flocking strength is high and less causing cracking and whitening at a head part, wherein bristle bundles (5) formed by binding synthetic resin bristles (4) are implanted in implantation holes (3) in the head part (1). The cross sectional shape of the implantation hole (3) is formed in a circular hole with a diameter of 1.8 mm or longer or a hole with a size equivalent to the circular hole. The cross sectional shape of the synthe...
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ORTHODONTIC APPLIANCE SHIELD COMPOSITION

(WO2006018809) 23.02.2006 A61K 6/00 RHEEDER, Christiaan Albertus Jacobus
This invention relates to an orthodontic appliance shield composition adapted to be applied to an orthodontic appliance to protect the mouth tissue of a person wearing the orthodontic appliance. The shield is in the form of a polyvinyl acetate in a gel form. The gel has superior adhesive characteristics over traditional orthodontic wax products and thus remains in position for a relatively longer period of time than prior art wax products. The gel is further translucent and therefore not as noticeable as prior art mouth guards, plastic shields, caps, and wax products being applied to the orthodontic appliance.
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SELF-CONTAINED DENTAL PROPHYLAXIS ANGLE WITH OFFSET ROTATIONAL AXIS

(WO2006017554) 16.02.2006 A61C 3/06 STADEKER, Wilkie, J.
The present invention discloses a self-contained dental prophylaxis angle with an offset rotational axis and methods for its use in cleaning, polishing, bleaching, bonding, etching, abrading, desensitizing, or otherwise treating teeth. Therapeutic content, such as dentifrice, is contained within the inventive prophylaxis angle, and is dispensed subject to operator control during use of the prophylaxis angle. An offset drive system is provided to power rotation of the dental tip in a system that can be physically separated from the storage and dispensing system for therapeutic content. A self-contained dental prophylaxis angle with an offset rotational axis according to the present invention may be used with a variety of shaped dental tips o...
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DENTAL POLYMERIZABLE COMPOSITION

(WO2006016649) 16.02.2006 A61K 6/00 KURARAY MEDICAL INC.
A dental polymerizable composition which comprises: (a) a fluorine compound comprising a chain polymer having a backbone comprising monomer units having a hydrophilic group and a fluoroalkyl-containing terminal group bonded to each end of the backbone; (b) a polymerizable monomer; and (c) a polymerization initiator. The dental polymerizable composition is suitable for use as, e.g., dental composite resins such as a dental composite filler, tooth crown material, and bonding material, dental adhesives such as a teeth-straightening adhesive, cavity-filling adhesive, and tooth fissure sealant, denture base materials, mucosal adjustment materials for denture bases, coating materials for application to a fissure sealant, tooth surface, or dental ...
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CLATHRATE OF CHLORINE DIOXIDE

(WO2006014527) 09.02.2006 A01N 25/04 CALLERAME, Joseph
Methods and compositions formed as a reaction product of mono-, or di-, or polysaccharide with organic, phosphoric, or boric acid, combined with chlorine dioxide or salt of chlorite, may be dry, water free, power, tablet, paste, or gel. Disinfectant for surfaces, skin, mouth, water, industrial processes, bacterial and fungal diseases. Methods of making chlorine dioxide by irradiating chlorite salt solution with UV and optionally an acid and optionally recovered by aeration.
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DENTAL COMPOSITIONS WITH SENSITIVITY RELIEF

(WO2006014365) 09.02.2006 A61K 8/00 DISCUS DENTAL IMPRESSIONS, INC.
A one-component prescription fluoride treatment composition having both fluoride efficacy and sensitivity relief is disclosed. The composition includes at least one metal fluoride and a nerve desensitizing agent such as potassium nitrate. The invention further includes a composition having at least one metal fluoride less than about 1.15% by weight of at least one metal fluoride; less than about 5 percent by weight of at least one alkali metal salt having desensitizing effect; at least one carrier; and at least one foaming agent that has thickening property. The composition may be formulated into a gel, a paste or any other convenient form, some of which contain abrasives.
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SECURITY DEVICE

(WO2006013223) 09.02.2006 E02D 29/14 LAFFITTE FIGUERAS, Mart
The invention relates to a security device that is secured to the mouth of an underground pipe (4) including an edge (2) and a hinged cover (5) having rising cylinders (6), a peripheral sealing gasket (30) being provided for. The cover (5) includes an opening provided with a screw fixed lid (8), one of the screws compresses a first electrical contact (9) sending a warning signal to a control center. Underneath the lid is provided a turning part (10) pulling in an angular fashion a closing handle (14) provided onto the edge. In the closed position, said handle (14) is located on top of the plate (18) integral with said edge (5), both having an access ramp providing automatic pre-closing. The closing position is provided through a second elec...
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NOVEL COMPOSITION FOR XEROSTOMIA

(WO2006013081) 09.02.2006 A61K 8/73 GLAXO GROUP LIMITED
An oral care compositon is described for use in the treatment or alleviation of the symptoms of dry mouth comprising polyvinyl pyrrolidone (PVP) or a derivative thereof, an anionic mucoadhesive polymer and an orally acceptable carrier or excipient.
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ORAL COMPOSITION

(WO2006012988) 09.02.2006 A61K 8/19 UNILEVER N.V.
A visually clear gel toothpaste composition comprising a sparingly soluble divalent metal salt, characterised in that the sparingly soluble divalent metal salt is fully solubilised by a chelating agent for the metal salt, the chelating agent having a log Ks1 for the divalent metal ion as herein defined of from 3.0 to 7.0.
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ORAL COMPOSITION

(WO2006012987) 09.02.2006 A61Q 11/00 UNILEVER N.V.
An opaque toothpaste composition and method for making such, the toothpaste comprising water, a zinc salt, a chelating agent for the zinc salt, the chelating agent having a log Ks1 as herein defined of from 3.0 to 7.0, and an abrasive present at from 10% to 70% by weight of the composition, said abrasive comprising calcium carbonate.
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COMPOSITION

(WO2006012977) 09.02.2006 A61K 8/27 UNILEVER N.V.
Toothpaste composition and method for making such, the toothpaste comprising water, a zinc salt, a chelating agent for the zinc, the chelating agent having a log Ks1 as herein defined of from 3.0 to 7.0, and calcium carbonate as abrasive.
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TOOTHPASTE COMPRISING CALCIUM CARBONATE AND ZINC CITRATE

(WO2006012967) 09.02.2006 A61K 8/27 UNILEVER N.V.
Toothpaste and method for making such, the toothpaste comprising calcium carbonate as abrasive, water and zinc salt substantially all of which is in the form of water-solubilised zinc citrate.
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ELECTRIC ORAL CLEANING DEVICE

(WO2006012224) 02.02.2006 A61C 15/00 REHCO, LLC
In one embodiment of the present invention, an electric oral cleaning device is provided and includes a handle (102) and a power supply (104) contained therein. The device has a motor (108) that drives a motor linkage (110), which includes a push rod (126) that has one end that engages and moves a dental cleaning head about a center pin to cause an oscillation motion of the head. The entire head assembly is also interchangeable such that a flossing tool (164) and various brushing tools may be utilized by the same device. The flossing tool (164) includes a piece of slacked flossing (168) material held between two arms (172) defined by the flossing tool (164).
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STRUCTURE MADE OF INTERCONNECTED ELONGATED CONTAINERS AND METHOD OF ASSEMBLING THE SAME

(WO2006011142) 02.02.2006 B65D 21/02 BOTTLEFLY LTD.
A structure and a method of assembling a structure made of interconnected elongated containers, such as bottles, are disclosed. Interfaces of a connector are connected to predetermined sites of different containers, respectively. The remaining connectors are interconnected with corresponding containers. The structure may further comprise at least one accessory interconnected with the structure. The configuration of a connector and of a connector interface and the location of a predetermined site to be connected with a corresponding connector interface are selected so as to produce a desired structure arrangement. Exemplary connector interface configurations are a bottle-mouth fitting and an attachment plate.
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LASER CURABLE POLYMERISABLE DENTAL COMPOSITION

(WO2006010631) 02.02.2006 A61K 6/08 DENTSPLY DE TREY GMBH
One-component heat-curate sealant composition for the protection of exposed dental surfaces, comprising (a) a polymerisable monomer and/or oligomer which has at least two polymerizable douse bonds per molecule, and (b) an initiator system comprising benzoylperoxide in an amount of at least 2 wt.-% based on the total composition.
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DENTAL ADHESIVE COMPOSITION

(WO2006010392) 02.02.2006 A61K 6/00 DENTSPLY DETREY GMBH
One component dental adhesive composition having a pH of at most 3, comprising (a) a polymerisable acrylate monomer or prepolymer, (b) a photoinitiator, and (c) a solvent comprising t-butanol.
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ORAL CARE FILM

(WO2006009737) 26.01.2006 A61K 9/00 COLGATE-PALMOLIVE COMPANY
A composition for delivery of an oral care substance to a dental surface upon application of the composition thereto is a flexible film comprising the oral care substance dispersed in a film-forming effective amount of a polymeric matrix having a hydrophilic component, e.g., vinylpyrrolidone (VP), and a hydrophobic component, e.g., vinyl acetate (VA), in a weight ratio selected such that the film is substantially dissolvable in saliva in a period of time effective for delivery of the oral care substance. The polymeric matrix illustratively comprises a poly(VP/VA) copolymer having a VP/VA weight ratio of about 90:10 to about 10:90.
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DENTAL/SURGICAL SEALANTS INCLUDING SHAPEABLE PARTICLES

(WO2006008499) 26.01.2006 A61L 24/00 DRFP HOLDINGS LIMITED
A sealant composition, suitable for surgical or dental use, comprises a sealant and, dispersed therein, one or more particles of a material which is prestressed and/or capable of undergoing expansion or contraction.
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METHODS AND SYSTEMS FOR CEMENTING WELLS THAT LACK SURFACE CASING

(WO2006008490) 26.01.2006 E21B 33/14 HALLIBURTON ENERGY SERVICES, INC.
A method for cementing a casing in an open well bore having no surface casing, wherein an annulus is defined between the casing and the well bore, the method having: sealing the annulus at the mouth of the well bore with a seal; pumping a cement composition into the annulus through the seal; and taking circulation fluid returns from the inner diameter of the casing. A system for cementing a casing in an open well bore having no surface casing, wherein an annulus is defined between the casing and the well bore, the system having: a seal of the annulus at the mouth of the well bore; a cement composition pump fluidly connected to the annulus through the seal; and a coupling connected to the exposed end of the casing for taking circulation flui...
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INJECTABLE BONE-REPAIRING BIOACTIVE MATERIAL CAPABLE OF FORMING GEL AND ITS PREPARATION METHOD

(WO2006007780) 26.01.2006 A61L 27/22 XU, Fang
The present invention discloses a injectable bone-repairing bioactive material capable of forming gel, and its preparation method. Each administering dosage of said material consists of component A l ml (alginate 10-40 mg, bone morphogenetic protein 0.1-1 mg, stabilizer 10-20 mg in 1 m1 sterile physiological saline) and component B 45-55 mg, wherein the component B has the following composition (per mg): water indissolvable calcium compound 0.05-0.15 mg, gluconolactone 0.05-0.3 mg, polyvinylpyrrolidone 0.004-0.016 mg, and a balance of filler. Said injectable bone-repairing material: (i) has the excellent biocompatibility; (ii) is safe and convenient in use; (iii) may be implanted into the site to be treated in bone disease patients without ...
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ANTI-MICROBIAL DENTAL FORMULATIONS FOR THE PREVENTION AND TREATMENT OF ORAL MUCOSAL DISEASE

(WO2006007136) 19.01.2006 A61K 9/70 ROSEN, Gerald M.
Compositions and methods are directed to antimicrobial compositions and articles that release NO from the composition and/or article in an amount effective to prevent gingival and other oral mucosal diseases.
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CALCIUM PEROXYPHOSPHATES AND USE THEREOF IN DENTAL COMPOSITIONS

(WO2006006998) 19.01.2006 A61K 8/24 ADA FOUNDATION
Calcium peroxyphosphate compounds and dental compositions comprising these compounds that combine both whitening/stain removal of teeth with remineralization are disclosed. The calcium peroxyphosphate compounds are capable of releasing, in an aqueous environment, whitening and reminiralization effective amounts of calcium ion, phosphate ion, and active oxygen. Preferred compounds are calcium peroxymonophosphate or calcium diperoxymonophosphate compounds. These compounds may be used in humans and other animals, including other mammals.
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DENTAL COMPOSITION CONTAINING AN EPOXY FUNCTIONAL CARBOSILANE COMPOUND

(WO2006005369) 19.01.2006 A61K 6/093 3M ESPE AG
The present invention relates to a dental composition comprising least one carbosilane compound comprising at least one Si-Aryl bond, at least one silicon atom, no Si - Oxygen bond, at least one aliphatic epoxy moiety, wherein said carbosilane compound has no glycidyl ether moieties; and an initiator, optionally filler and optionally additive components selected from the group of modifiers, stabilizers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavourings.
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DENTAL COMPOSITION CONTAINING UNSATURATED CARBOSILANE CONTAINING COMPONENTS

(WO2006005368) 19.01.2006 A61K 6/093 3M ESPE AG
The invention relates to a dental composition comprising a) carbosilane containing component (A) comprising at least 1 Si - Aryl bond, at least 1 silicon atom, at least 2 unsaturated moiety, no Si - Oxygen bond, b) Si-H functional component (B), c) initiator (C), d) optionally filler (D), and e) optionally component (E) selected from modifiers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavourings.
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DENTAL COMPOSITION CONTAINING SI-H FUNCTIONAL CARBOSILANE COMPONENTS

(WO2006005366) 19.01.2006 A61K 6/093 3M ESPE AG
The invention relates to a dental composition comprising a) carbosilane containing component (A) comprising at least 1 Si - Aryl bond, at least 1 silicon atom, at least 2 Si-H functional moieties, no Si - Oxygen bond, b) unsaturated component (131), and/or epoxy component (132), c) initiator (C), d) optionally filler (D) and e) optionally component (E) selected from modifiers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavorings.
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DENTAL COMPOSITION CONTAINING EPOXY FUNCTIONAL POLYMERIZABLE COMPOUNDS

(WO2006005365) 19.01.2006 A61K 6/087 3M ESPE AG
The present invention relates to dental compositions comprising a halogenated epoxy functional ether derivative comprising at least one aryl alkyl ether moiety, at least one halogen atom attached to each aryl residue of the aryl alkyl ether moieties, at least two aliphatic epoxy moieties, no glycidyl ether structure, an initiator, optionally filler and optionally additive components selected from the group of modifiers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavourings.
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DENTAL COMPOSITION CONTAINING UNSATURATED HALOGENATED ARYL ALKYL ETHER COMPONENTS

(WO2006005364) 19.01.2006 A61K 6/093 3M ESPE AG
The invention relates to a dental composition comprising a) halogenated aryl alkyl ether component (A) comprising at least 1 aryl alkyl ether moiety, at least 1 halogen atom attached to each aryl residue of the aryl alkyl ether moieties, at least 2 unsaturated moieties, b) Si-H functional component (B), c) initiator (C), d) optionally filler (D), and e) optionally component (E) selected from modifiers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickness, surfactants, odorous substances, diluting agent(s) and flavourings.
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DENTAL COMPOSITION CONTAINING UNSATURATED CARBOSILANE CONTAINING COMPONENTS

(WO2006005363) 19.01.2006 A61K 6/093 3M ESPE AG
The invention relates to a dental composition comprising a) carbosilane containing component (A) comprising at least 1 Si - Aryl bond, at least 1 silicon atom, at least 1 unsaturated moiety, no Si - Oxygen bond, b) initiator (B), c) optionally filler (C) and d) optionally component (D) selected from modifiers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavouring.
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TOOTH WHITENING DEVICE

(WO2006005049) 12.01.2006 A61C 5/00 PROFESSIONAL DENTAL TECHNOLOGIES, INC.
The invention is a locally mounted light source for light activation of tooth whitening compositions. A support in the form of a bridge attached to a retractor or as part of a mouth guard has integral therewith, a small and lightweight light source, such as could be provided by one or more high-intensity LED's, though other light sources could be used. The light source may be in the form of an array, powered by either a direct electrical connection to a power supply or by battery power, for example, with a battery pack worn by the user. The light source is thus located in proximity to the tooth surfaces regardless of head movement or orientation, increasing user mobility and comfort.
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A PALATAL PLATE AND A METHOD OF PRODUCING SAID PLATE

(WO2006004541) 12.01.2006 A61C 7/10 BENGTSSON, Karin
The present invention relates to a palatal plate having a stimulating member, comprising a thin-walled curved portion (2), the convex surface (8) of which being adapted to the palate of a user, a front edge portion (5), a rear edge portion (6) and two side edge portions (7A, 7B), as well as retainer means (3, 4) for retaining the palatal plate (1) inside the user's mouth, said stimulating member (9) being at least essentially chemically integrated with the inner surface (16) of said curved portion (2), and in that said retainer means (3, 4) are at least essentially formed from a material that is chemically integrated with the material of said curved plate (2), and that the means are designed to allow for a low total weight of the palatal pl...
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CELL-INDEPENDENT FABRICATION OF TISSUE EQUIVALENTS

(WO2006003442) 12.01.2006 A61L 27/24 UCL BUSINESS PLC
This invention relates to cell-independent processes which mimic cellular bioremodelling and produce organised biomaterials which have mechanical properties and viable cell densities suitable for use as functional tissue implants. The biomaterials are produced by providing a gel comprising a matrix of scaffold fibres of and an interstitial fluid; and plastically compacting the gel to produce the biomaterial. The biomaterials may comprise 3D structures such as layering, alignment and meso-scale zonal heterogeneities of cells and matrix which mimic native tissue structure. Biomaterials with biomimetic structure as described herein may be useful in a range of therapeutic applications.
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LOW SHRINKAGE AND LOW STRESS DENTAL COMPOSITIONS

(WO2006002086) 05.01.2006 A61K 6/083 DENTSPLY INTERNATIONAL INC.
A composition of macrocyclic oligomer with at least one polymerizable group, (meth)acrylate, for example.
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ENDOSCOPE CLEANING AND DISINFECTING SYSTEM, ENDOSCOPE, AND ENDOSCOPE CLEANING AND DISINFECTING DEVICE

(WO2006001336) 05.01.2006 A61B 1/12 OLYMPUS CORPORATION
An endoscope connection section (31) that is connected to a connector section (105a) of an endoscope body (101) and reception side mouth pieces (36a-39a) that are individually connected to conduits (106-109) of the endoscope body (101) are installed in a cleaning/ disinfecting tank (4) of an endoscope cleaning/disinfecting device (1). To clean and disinfect the endoscope body (101), the connector section (105a) is faced to the endoscope connection section (31) while being placed at a predetermined position, and after that a switch is turned on. Then, an electromagnet provided at the endoscope connection section (31) is excited, and the connector section (105a) is attracted and fixed by magnetic force produced.
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ULTRASONIC ORAL HEALTH CARE APPLIANCE

(WO2006001224) 05.01.2006 A61C 17/00 SUNSTAR INC.
[PROBLEMS] To provide an ultrasonic oral health care appliance enabling an increase in the freedom degree of the design of an ultrasonic transmission part, capable of preventing discomfort from occurring due to a rise in temperature, capable of preventing air layers from occurring in a liquid in a liquid supply passage at a liquid reservoir part and a jaw part, capable of efficiently cleaning a mouth cavity by supplying the less amount of a liquid of such a degree that can maintain a transmission efficiency, having excellent usability, and capable of providing the large freedom degree of design. [MEANS FOR SOLVING PROBLEMS] This ultrasonic oral health care appliance is characterized by comprising the liquid supply passage (5) extending from...
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Title Pub. Date Int. Class Applicant
SANITIZING METHOD

(WO2005123147) 29.12.2005 A61L 2/16 EBIOX LIMITED
Ductwork used for the supply of potable water in dental surgeries is prone to undesirable build up of biofilm and associated bacteria. These may be combated effectively by applying to the ductwork a composition comprising: a metal silicate or silicate complex; a metal phosphate or polyphosphate or orthophosphoric acid; and a non-ionic or amphoteric surfactant.
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DENTAL AND MEDICAL INSTRUMENTS COMPRISING TITANIUM

(WO2005122942) 29.12.2005 A61C 5/02 LUEBKE, Neil, Hamilton
Endodontic instruments for use in performing root canal therapy on a tooth are disclosed. In one form, the instruments include an elongate shank having a cutting edge extending from a distal end of the shank along an axial length of the shank. The shank comprises a titanium alloy, and the shank is prepared by heat-treating the shank at a temperature above 25 C in an atmosphere consisting essentially of a gas unreactive with the shank. In another form, the endodontic instruments have an elongate shank having a cutting edge extending from a distal end of the shank along an axial length of the shank. The shank consists essentially of a titanium alloy selected from alpha-titanium alloys, beta-titanium alloys, and alpha-beta-titanium alloys...
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A FOLDABLE TOOTHBRUSH, A TOOTHPASTE SACHET AND A DENTAL CARE KIT

(WO2005122828) 29.12.2005 A46B 5/00 JORDAN AS
A dental care kit including a holder comprising a first, ventilated compartment for storing a toothbrush, a second, closable compartment which can be opened for inserting or replacing a toothpaste container with a nozzle, and a lid for closing both compartments simultaneously with closure of a nozzle on the toothpaste sachet by means of a cap or closure securable in the lid, or an elastically yielding pad secured in the lid. A folding toothbrush comprising a through opening in the handle and a toothpaste sachet are also described.
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SELECTION AND USE OF LACTIC ACID BACTERIA FOR REDUCING DENTAL CARIES AND BACTERIA CAUSING DENTAL CARIES

(WO2005121312) 22.12.2005 A61P 1/02 BIOGAIA AB
New strains of Lactobacillus that have been selected for their capability of improved reduction the number of Streptococcus mutans in the mouth of mammals through inhibiting activity in combination with better binding to the oral mucins and dental plaque, thereby preventing, reducing or treating dental caries, and products derived from said strains, including agents for treatment or prophylaxis of caries for administration to humans.
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HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION

(WO2005121200) 22.12.2005 A61K 6/093 RHODIA CHIMIE
The invention relates to highly charged cationic dental compositions, comprising at least one compound (A) which may undergo cationic reactions, at least one dental filling (B), optionally at least one dispersant (C), comprising at least one organic polymer or copolymer, at least one cationic photocuring agent and optionally at least one photosensitizer (E), said composition being characterised in that at least one dental filling (B) is treated by a) at least one organosilicon coupling agent (F) and b) at least one compound (G), said organosilicon coupling agent (F), comprising at least one reactive function (frA) directly bonded to a silicon atom forming a chemical bond to the dental filling after activcation and at least one reactive func...
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APOPTOSIS-INDUCING POLYPEPTIDES

(WO2005121169) 22.12.2005 A61K 39/12 ACADEMIA SINICA
An isolated water-soluble VP1 polypeptide of foot-and-mouth disease virus and a nucleic acid encoding the polypeptide. Also disclosed are a pharmaceutical composition containing the polypeptide or nucleic acid and related methods of inducing apoptosis and treating an apoptosis-related disorder.
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PHOTOPOLYMERISABLE DENTAL COMPOSITION

(WO2005120439) 22.12.2005 A61K 6/093 RHODIA CHIMIE
The invention relates to a photopolymerisable dental composition, by means of radiation at a wavelength greater than 390 nm, comprising a photosensitizer (E) which is a salt of a thioxanthone substituted by at least one group (G), comprising an ammonium function. Said composition has the advantage of resolving the problems of chromatic stability of finished dental products (after cross-linking).
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A CHARGEABLE VACUUM CLEANER

(WO2005120323) 22.12.2005 A47L 5/00 RONFORD INDUSTRIAL LTD.
The invention relates to a chargeable vacuum cleaner, which is composed of the main body of the cleaner and a mop body. The main body of cleaner includes a handle, a switch button, a vent lip, a hanging button of the mop, a motor, a wind blade and a batterry. A motor, which can drive a cleaning roller with a brush to rotate, is mounted in the mop body. The mop body is detachably inserted into a flat mouth head in the forepart of the main body of the cleaner. The mop body can be replaced by the fittings such as a detachable sharp mouth with high sucking power and a detachable roller for cleaning cloth materials. A detachable transparent dust--collecting box is provided in the cavity in the forepart of the main body of cleaner. A lighting...
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POCKET AUTOMATIC ASSEMBLY FOR WASHING AND MAINTINING THE DENTAL HYGIENE

(WO2005120287) 22.12.2005 A46B 5/00 VELICKOVIC, Pjer-Mise
Pocket automatic assembly composed of a small number of smart parts, enables the assembly functioning at the simultaneous performing of the entire working cycle in and on the assembly. The basic advantage is: - pocket dimensions, the anatomic shape according to the hand fist, - universal for left-handed and right-handed person, - activation with one move of the first thumb, - coming-out of the brush (18) on the height of 18cm and setting a dose cf the tooth paste on it, - correct position of the brush for cleaning the teeth from above downwards, - easy foldable parts that can be decomposed and cleaned, - the reservoir contains 9 doses of the tooth paste and it can be refilled, - the brush head (26) that can be replaced after it is worn out,...
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DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES

(WO2005117849) 15.12.2005 A61K 31/015 UNIGEN PHARMACEUTICALS, INC.
The present invention implements a strategy that combines an enzyme inhibition assay with a chemical dereplication process to identify active plant extracts and the particular compounds - diarylalkanes and/or diarylalkanols within those extracts that specifically inhibit binuclear enzyme function. Included in the present invention are compositions of matter comprised of one or more of diarylalkanes and/or diarylalkanols, which inhibit the activity of binuclear enzymes, particularly tyrosinase and which prevent melanin overproduction. The present invention also provides a method for inhibiting the activity of a binuclear enzyme, particularly tyrosinase and a method for preventing and treating diseases and conditions related to binuclear enzy...
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ANTI-STAINING ANTIBACTERIAL DENTIFRICE

(WO2005117821) 15.12.2005 A61K 7/16 COLGATE-PALMOLIVE COMPANY
An anti-staining, antibacterial dentifrice comprises an anti-staining effective amount of an orally acceptable polymer or copolymer that comprises a plurality of monomeric groups of formula (I) wherein (a) one of A and A' is hydrogen and the other is a moiety (X)n(R)m, (b) n in individual such moieties is independently 0 or 1, (c) linking groups X if present independently comprise an oxygen, sulfur, nitrogen, phosphorus or silicon atom, (d) where n is 0, m is 1, and where n is 1, m is independently an integer from 1 to 3 as determined by X, (e) terminal groups R are independently hydrogen or C1-18 organic radicals, and (f) M and M' are independently selected from hydrogen, alkali metal and ammonium; said polymer or copolymer having an avera...
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PHYSIOLOGICAL COOLING COMPOSITIONS

(WO2005117811) 15.12.2005 A23L 1/226 MILLENNIUM SPECIALTY CHEMICALS
The present invention provides, in one aspect, a physiological cooling composition comprising at least one cyclohexane carboxamide, at least one acyclic carboxamide, and at least one stereoisomer of menthyl lactate. In another aspect, disclosed is a method for producing such composition. In still another aspect, disclosed are various consumer products comprising a physiological cooling composition comprising at least one cyclohexane carboxamide, at least one acyclic carboxamide, and at least one stereoisomer of menthyl lactate.
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USE OF NANOPARTICLES TO ADJUST REFRACTIVE INDEX OF DENTAL COMPOSITIONS

(WO2005117806) 15.12.2005 A61K 6/083 3M INNOVATIVE PROPERTIES COMPANY
The present invention features ionomer compositions containing nanofillers that provide the composition with desirable aesthetic properties (e.g., optical translucency). The compositions can be used in a variety of dental and orthodontic applications, for example, as adhesives, cements, restoratives, coatings and sealants.
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DENTAL CEMENT WITH GRAFTED POLYACID COMPOSITE PARTICLES

(WO2005117804) 15.12.2005 A61K 6/08 DENTSPLY DETREY GMBH
A dental cement composition comprising (i) a particulate reactive inorganic filler capable of leaching metal ions in the presence of an acid, and (ii) composite particles with grafted polyacidic polymer chains, which are obtainable by a process comprising the following steps: (a) polymerizing one or more free radically polymerizable monomers containing optionally protected acidic groups in the presence of (a1) an initiatior system comprising initiator particles displaying a moiety comprising a radically transferable atom or group as a polymerization initiation site; and (a2) a catalyst facilitating controlled/living polymerisation, and (a3) optionally further polymerizable monomers, for forming a composite particle with grafted optionally p...
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METHOD AND DEVICE FOR CLEANING DENTAL POLISHERS

(WO2005115645) 08.12.2005 B08B 9/02 SOCIETE POUR LA CONCEPTION DES APPLICATIONS DES TECHNIQUES ELECTRONIQUES - SATELEC
The invention relates to a method for maintaining and cleaning the conduits (2a, 3a) of a dental polisher (1), of the type that comprises the pressurised spraying of a polishing powder (7) onto a tooth surface. The inventive method is characterised in that it includes an operational phase comprising the pressurised injection of a solution (9), in which the powder (7) is soluble, into at least some of the conduits (2a, 3a) through which said powder (7) passes.
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INTRAORAL APPARATUS AND METHOD FOR BLOOD AND SALIVA MONITORING & SENSING

(WO2005115225) 08.12.2005 A61B 5/00 BEISKI, Ben, Zion
Controlled-specimen-sampling oral devices are implanted or inserted into an oral cavity, built onto a prosthetic tooth crown, a denture plate, braces, a dental implant, or the like. The devices are replaced as needed. The controlled specimen sampling may be passive, based on a dosage form, or electro-mechanically controlled, for a high-precision, intelligent, specimen sampling. Additionally, the controlled sampling may be any one of the following: sampling in accordance with a preprogrammed regimen, sampling at a controlled rate, delayed sampling, pulsatile sampling, chronotherapeutic sampling, closed-loop sampling, responsive to a sensors input, sampling on demand from a personal extracorporeal system, sampling regimen specified by ...
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BRUSH HEAD FOR ELECTRIC AND/OR MANUAL TOOTHBRUSHES

(WO2005115196) 08.12.2005 A46B 7/02 BRAUN GMBH
The invention relates to a compact brush head (4) comprising a bristle carrier, on which bristles (5, 6, 7) and an elastic element (10) for holding a cleaning and/or dental care substance for the mouth, teeth and/or gingiva are fixed. The elastic element (10) is connected to the bristle carrier (8) by means of a support element (14). The bristle carrier (8) consists of a first plastic, the support element (14) of a second plastic and the elastic element (10) consists of a third plastic.
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SALT OF 4- OR 5- AMINOSALICYLIC ACID

(WO2005115075) 08.12.2005 C07C 65/10 ANTIBE THERAPEUTICS INC.
The present invention provides L-arginine salts of 4-ammosalicylic acid and 5-ammosalicylic acid (mesalamine) Pharmaceutical compositions containing these L-argmme salts are useful for the treatment of inflammatory conditions of the gastrointestinal (GI) tract such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) The compositions may be used to treat Crohn's disease, gastritis, celiac disease, peptic ulcer disease, inflammatory conditions of the mouth and esophagus, pre-cancerous lesions of the stomach, non-ulcer dyspepsia, bacterial overgrowth, peptic ulcer disease, fissures of the intestine, ulcerative colitis, infectious colitis, precancerous conditions of the colon, proctitis, inflammation associated with hemorrhoi...
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LAY-OUT IN TONGUE CLEANER

(WO2005112794) 01.12.2005 A61B 17/24 DA CONCEIO, Maurcio, Duarte
This abstract refers to a patent of a utility model for tongue cleaner, belonging to the field of mouth hygiene devices, which received disposition to provide a better use and efficiency when compared to the others, and foresees body (1) equipped with tongue cleaning device, comprised essentially of: one scraping edge (3) incorporated in the extreme curve sector of stretch (2) and designed in relation to one of the faces of this stretch (2); and of a brush (4), which acts on the tongue and is opposite to the edge (3).
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HEAT TRANSFER AND AIR FILTER METHOD

(WO2005111510) 24.11.2005 F24D 11/00 BAKIRCI, Seydi
In order to remove the heating need in the heating systems, in the heat transfer method in order to provide for heating by carrying hot water with tankers from the central facility outside the settlement to the tanks in the regional heating systems center, the central heating net water coming from the (X) circulation entrance flows being heated to the (2) entrance blocks through (1) entrance pipes, from the (2) entrance blocks to the (4) return blocks with (3) pipes, and from the (4) return blocks to the (Y) circulation return pipe through (5) return pipes. In order to prevent the heat loss by emission during the hot water filling and emptying a (8) inflammable hose is located between the emission mouths of the (14) tank and the (13) tank. ...
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INJECTION MOULDING PLASTIC CONTAINER CAPS

(WO2005110707) 24.11.2005 B29C 45/44 CARBONITE CORPORATION
A method of injection moulding a rotationally symmetrical container cap includes injecting molten plastic material into a mould cavity (50) defined by at least two mould members (52, 56, 58, 60, 62). The mould cavity is shaped to form a container cap comprising a closure plate (30, 32), which extends, in use, over the mouth and rim of a container, an integral depending skirt (18), which, in use, extends down around the outer surface of the rim (8) of the container and a fastening flange (20), which is integral with the inner surface of the skirt and extends generally away from the closure plate and inwardly towards the axis of the cap. The plastic material is permitted to solidify within the cavity. A first mould member (58), which defines ...
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COMPOSITION, COMPISING HYDROFLUORIC ACID, FOR INHIBITING DENTAL EROSION

(WO2005110347) 24.11.2005 A61K 7/18 IN 2 GROUP AS
The present invention relates to a composition, for inhibiting dental erosion, and the use thereof. The composition comprises an aqueous solution of hydrofluoric acid, in which the concentration of hydrofluoric acid is 0,05% - 2,00% and the pH is between 2,5 and 4,5.
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COMPOSITION CONTAINING NANO-CRYSTALLINE APATITE

(WO2005110339) 24.11.2005 A61K 6/06 S &C POLYMER, SILICON- UND COMPOSITE SPEZIALITTEN GMBH
This invention describes compositions containing nano-crystalline apatite useful as bone- or preferably as tooth restorative materials. The materials produced, using the composition have improved properties in the areas of esthetics, hardness, translucency, surface polishability, strength and the capability to release and to take ions up in respect of a biological environment.
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DENTAL STICK

(WO2005110270) 24.11.2005 A61C 15/02 IZMAYLOV, Viktor Ivanovich
The invention relates to medicine, in particular to stomatology. The inventive dental stick comprises a holder (1) provided with oppositely deflected massaging (2) and cleaning elements tapered towards the ends thereof. Said holder is embodied such that it is inflectionally bent in the middle section thereof and two symmetrical oppositely shifted with respect to a symmetry axis (6) segments are formed. Said symmetrical segments of the holder (1) have circular cross sections (7) reducing away from the middle of the holder towards the massaging elements (2). Said massaging (2) and cleaning elements are formed by two flat faces which are perpendicular to the holder axis plane. The massaging elements are deflected to the sides which are opposit...
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APPARATUS FOR CLEANING ORTHODONTIC AND DENTAL APPLIANCES

(WO2005110269) 24.11.2005 A61C 3/00 BERMAN, Richard, H.
A hand-held cleaning device includes an elongated handle having an operative end. The operative end includes a flattened, relatively small hook, and a flexible neck. A cover can be provided to protect the operative end of the cleaning device. To use the cleaning device, for example, to clean between the palate to the wearer of a palatal expander appliance and portions of the palatal expander appliance, the hook end is slid between the palate of the wearer of the appliance or by another person, and any food or other debris trapped in the space between the appliance and the palate of the wearer can be swept aside, pushed forward or engaged with the hook and pulled from between the palate and the appliance.
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ORAL CARE TOOTHBRUSH

(WO2005110149) 24.11.2005 A46B 9/04 COLGATE-PALMOLIVE COMPANY
An oral care toothbrush includes a head mounted to one end of the handle containing a plurality of oral care elements. An oral care accessory is mounted to the opposite end of the handle. An oral care material dispenser is mounted in the head within the cleaning field defined by the oral care elements. The toothbrush is preferably made of small size and of lightweight so as to be readily portable for use away from the home.
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METHOD OF INDUCING HUMAN PULP CELL DIFFERENTIATION AND COMPOSITION FOR DENTIN REGENERATION

(WO2005108558) 17.11.2005 A61L 27/00 HITACHI MEDICAL CORPORATION
It is intended to provide a method of inducing the differentiation of human pulp cells into odontoblastic cells and a method of regenerating dentin to thereby enable the treatment of patients with dental diseases such as decay. Namely, a method of producing odontoblastic cells the differentiation into which has been induced comprising culturing at least one of isolated human pulp cells and cells capable of differentiating into human pulp cell in the presence of 1,25(dihydroxy)vitamin D3, dexamethasone and -glycerophosphate.
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METHOD AND DEVICE FOR ENHANCING THE TREATMENT OF TEETH AND GUMS

(WO2005107638) 17.11.2005 A61B 1/24 REMEDENT NV
The present invention relates to an autonomous device comprising a trough, shaped for the immersion of teeth and/or gums of a dental arch, or a dental brace and one or more electrical components which provide functionality. It further relates to methods for whitening teeth, relieving pain, treating bacteria, treating bad breath, and healing. It further relates to inserts for use in said device.
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METHOD AND DEVICE FOR ENHANCING THE TREATMENT OF TEETH AND GUMS

(WO2005107637) 17.11.2005 A61B 1/24 REMEDENT NV
The present invention relates to an autonomous device comprising a trough, shaped for the immersion of teeth and/or gums of a dental arch, and one or more electrical components which provide functionality. It further relates to methods for whitening teeth, relieving pain, treating bacteria, treating bad breath, and healing. It further relates to inserts for use in said device.
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METHOD AND DEVICE FOR ENHANCING THE TREATMENT OF TEETH AND GUM

(WO2005107636) 17.11.2005 A61C 19/06 REMEDENT NV
The present invention relates to an autonomous device comprising a trough, shaped for the immersion of teeth and/or gums of a dental arch, one or more means to provide physical stimulation and optionally one or more means to provide heat. It further relates to methods for cleaning teeth, relieving pain, treating bacteria, treating bad breath, loosening plaque and healing. It further relates to inserts for use in said device.
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A CLEANING APPARATUS

(WO2005107562) 17.11.2005 A47L 11/20 DU, Juewei
A cleaning apparatus comprises a cleaning belt, a suction apparatus, and a first cleaning surface. Said cleaning belt winds across the first cleaning surface, and the cleaning belt is capable of cleaning a surface to be cleaned through contacting with it. Said cleaning apparatus further includes a strip-shaped suction mouth provided near the place where the cleaning belt winds around the first cleaning surface. The suction mouth extending along a width direction of the cleaning belt connects a ventilative collection bag. The air is drawn into the ventilative collection bag via the suction mouth by said suction apparatus. The gap provided near the cleaning surface is used as the suction mouth in the cleaning apparatus, so that the cleaning a...
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DENTAL HANDPIECE LUBRICATING APPARATUS

(WO2005106316) 10.11.2005 F16N 7/30 FEE, Tom
A cleaning and lubricating apparatus (10) for a dental handpiece (H) or other device includes a handpiece mounting base (20) having a handpiece mounting structure (30); a lubricant reservoir (40); a compressed air chamber (60); a compressed air source connection structure in fluid communication with the compressed air chamber (60) and with the lubricant reservoir (40); a valve pin (72) and a valve pin slide passageway (70) extending from a slide passageway opening in the mounting base (20) to the air chamber (60) and slidably containing the valve pin (72) so that the valve pin (72) has a valve pin exposed end (74) extending outwardly from the mounting base (20) and the valve pin (72) has a valve pin inward end (76) and has a lateral lubrica...
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SEDIMENT LEVEL PROBE

(WO2005104987) 10.11.2005 B04B 11/04 DRR DENTAL GMBH &CO. KG
The invention relates to a level probe (78) for a collecting vessel of an amalgam separator, which comprises a slightly movable transmitting element (102) of a position measuring device in the form of a plate with five rolling units (152), guiding the transmitting element (102) together with a multi-channel guide rail (99) in three directions, perpendicular to each other. A sealed embodiment of a connecting rod (62), connecting the transmitting element (102) to a float (52), comprises a sealing bellows (164), one end of which is secured to a housing wall and the other end at a point of the connecting rod (62), away from the passage point of the connecting rod (162) through the housing wall.
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BALL LENS FOR USE WITH A DENTAL CURING LIGHT

(WO2005102203) 03.11.2005 A61C 1/00 ULTRADENT PRODUCTS, INC.
A ball lens (10) includes a connector body (12) that couples or attaches to a dental curing light (30) so as to capture at least some of the light emitted by the light source (28), an elongate light guide (14) extending from the connector body (12), and a light-emitting ball (16) at an end of the light guide (14) distal to the connector body (12). The ball (16) can be used to hold a matrix band against an adjacent tooth prior to and/or while incrementally curing a light curable composition.
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BREATH FRESHENING CONFECTIONERY PRODUCTS AND METHODS OF MAKING AND USING SAME

(WO2005102066) 03.11.2005 A23G 3/00 WM. WRIGLEY JR. COMPANY
A confectionery product comprises a first side and a second side generally opposite to the first side; the second side comprising an abrasive surface that is suitable for scrubbing the top surface of a tongue within the oral cavity. In preferred embodiments the first side is smooth, and may be domed shaped and generally fit the roof of the mouth. The abrasive surface may be provided by 1) a formed, uneven surface, 2) by including abrasive inclusions in the composition making up the second surface, or 3) a combination of a formed, uneven surface and abrasive inclusions. The confectionery product is preferably a hard confectionery, but may also be a chewing gum product. A preferred confectionery product comprises a second side with a width an...
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TOOL FOR OPENING/CLOSING COVER

(WO2005100231) 27.10.2005 B25B 13/50 KOBAYASHI PHARMACEUTICAL CO., LTD.
[PROBLEMS] To provide a tool for opening/closing a cover capable of efficiently opening and closing the cover of a drum can by compact structure. [MEANS FOR SOLVING PROBLEMS] This tool (1) for opening/closing the cover used for opening/closing the drum can in which two mouth parts with different diameters are formed in a top plate, a large cover and a small cover are threaded to the mouth parts, the large cover and the small cover comprise engagement members on the surface thereof, and at least either of the large cover and the small cover is covered by a protective cover. The tool comprises a bar-like member (10) having an insert part (12) at one end thereof and a flat plate-like opening/closing member (20) fitted to the other end of the b...
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LIQUID COMPOSITION AND PROCESS FOR PRODUCING THE SAME

(WO2005099765) 27.10.2005 A61K 9/08 KOBAYASHI PHARMACEUTICAL CO., LTD.
[PROBLEMS] To provide a liquid composition which has improved pharmaceutical stability and which not only effectively removes the pain attributable to a pharyngeal disease but gives a refreshing feeling to the mouth. [MEANS FOR SOLVING PROBLEMS] The liquid composition comprises a multi-component liquid preparation comprising a terpene alcohol, a polyhydric alcohol, and a lower alcohol.
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COMPOSITIONS FOR ORAL HYGIENE AND METHOD FOR USING SAME

(WO2005099658) 27.10.2005 A61K 33/00 CELL IONIX INC.
The present invention generally relates to oral compositions such as toothpastes, toothpowders, liquid dentrifices, mouthwashes, rinses, dental floss, denture cleansers, chewing gums, lozenges and the like. In particular, it relates to such oral compositions that include cesium and rubidium salts. In one aspect of the present invention, a composition for oral use is provided. The composition includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2. In another aspect of the present invention, a method for improving oral hygiene in a mammal is provided. The method involves taking a volume of a solution into the mammal's mouth, where the solution includes a cesium or rubidium salt and water ...
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CHEMICAL COMPOSITIONS

(WO2005098538) 20.10.2005 C08L 101/00 HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Chemical compositions are disclosed. One exemplary composition, among others, includes: a basic component, an acidic component, at least one acrylate component, oxidizing agent, reducing agent, and a binder. The binder includes a viscosity modifier and a surface tension modifier. The binder is capable of stimulating a reaction between the basic component and the acidic component. A portion of the binder is capable of undergoing a polymerization reaction between at least one acrylate component, the oxidizing agent, and the reducing agent. The polymerization reaction being initiated by the redox reaction between the oxidizing agent and the reducing agent.
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ASSAY METHOD FOR DETERMINING MUCOSAL NEUTROPHIL COUNTS IN NEUTROPENIA PATIENTS

(WO2005098020) 20.10.2005 A61K 49/00 BINAX, INC.
Based on recent investigations showing iatrogenic, profound neutropenia (and the fever spikes that often accompany it, which muste be medicated immediately to avoid the risk of life-threatening infection) can accurately be monitored by obtaining dialy mucosal neutrophil counts from the patients oral mucosa rather than obtaining daily counts of the patients blood neutrophils as in the past, a mouth wash method has been developed for collecting muscosal neutrophils. The mouth wash samples so collected are delivered directly, or in aqueous dilution, to a sample pad supported on a strip which sample pad has deposited thereon reagents enabling a colorimetric, fluorescent or chelimunescent assay of the quantity of an enzyme characte...
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HEALTHCARE AND COSMETIC COMPOSITIONS CONTAINING NANODIAMOND

(WO2005097045) 20.10.2005 A61K 33/44 SUNG, Chien-Min
Nanodiamonds can be included in various compositions to take advantage of the ability of nanodiamond to bond with biological materials and to improve mechanical strength. Nanodiamonds can be dispersed in a biologically acceptable carrier to form various nanodiamond compositions. The presence of nanodiamonds can increase binding with many biological materials, making the compositions of the present invention useful for a large variety of purposes such as cleansing, testing and identification of materials, and treatment of adverse conditions. Specific examples of nanodiamond compositions that can be formulated include deodorants, toothpastes, shampoos, antibiotics, dermal strips, DNA test strips, skin cleansers, and the like. Similarly, nanod...
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BUCCAL BACTERIA ULTRASONIC WASHER FOR CARE

(WO2005096986) 20.10.2005 A61C 17/00 MORIYAMA, Toshio
A buccal bacteria ultrasonic washer (1) allowing even a cared person such as a manually-handicapped aged person to be able to solely washing the inside of an oral cavity (such as tooth brushing) without requiring assistance by a carer, comprising a held part (3) formed in a horse shoe shape so that the person can hold it between the upper teeth and lower teeth, wherein an oscillating element (9) capable of performing ultrasonic vibration is installed in the held part (3). An elastic member is formed on the outer surface of the held part (3), and a low vibration imparting part (4) for providing use feeling is installed at the base part (20A) of the held part. Since a flange part (12) is formed in a boundary between the held part (3) and the ...
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IMPROVED DENTAL WHITENING METHOD

(WO2005094768) 13.10.2005 A61K 8/22 COLGATE-PALMOLIVE COMPANY
A method for whitening a dental surface comprises nonsimultaneously applying a whitening composition to the surface, the whitening composition comprising at least one orally acceptable peroxy compound, and directing a volume of up to about 2.5 ml of an atomized activating composition on to the surface, wherein the activating composition comprises, in the volume so directed, a peroxy compound activating effective amount of at least one orally acceptable basifying agent, and wherein applying the whitening composition and directing the activating composition are separated by an interval not greater than a peroxy compound activating effective interval. The atomized composition can be directed on to the dental surface before or after application...
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THE MOST COMPLETE TOOTHPASTE 'CHAMELEON'

(WO2005094767) 13.10.2005 A61Q 11/00 CIGULOV, Dragisa
Before, and for all time of brushing teeth, foam color is green and will not turn into opposite color until overdue minimal time. When color becomes red, brushing is ended. This changing color method can enable always same time of brushing teeth which is recommend by dentistry health care institutes and producers.
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ORAL CARE COMPOSITIONS COMPRISING POLYASPARTATE

(WO2005094765) 13.10.2005 A61K 8/64 THE BOOTS COMPANY PLC
There is described the use of polyaspartate to inhibit the formation of stains upon the teeth, or to remove stains from the teeth. Also described are oral care compositions comprising polyaspartate in an amount effective to inhibit prevent the formation of, or to remove, stains upon the teeth, the composition being substantially free of non-ionic dock copolymers, in particular polyoxyethylene, polyoxyethylene block copolymers and polyoxyethylene, polyoxypropylene block copolymers of ethylene diamine.
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DENTAL SEALANT COMPOSITION FOR THE PROTECTION OF HARD TISSUE

(WO2005094757) 13.10.2005 A61K 6/087 DENTSPLY DE TREY GMBH
A dental sealant composition for protection of an exposed dental surface, comprising a heat-curable step-growth polymerization system.
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LASER CURABLE POLYMERISABLE COMPOSITION FOR THE PROTECTION OF HARD TISSUE

(WO2005094756) 13.10.2005 A61K 6/083 DENTSPLY DETREY GMBH
One-component heat-curable sealant composition having a viscosity of at most 5 Pas (23C) for the protection of exposed dental surfaces, comprising (a) a polymerisable monomer and/or oligomer having at least two polymerizable double bonds per molecule , and (b) an initiator system comprising a thermally stable initiator having a 10 hour half-life decomposition temperature of from 95C to 135 (0.1 M in benzene); wherein the composition further contains a precursor for a filler which is an alkoxysilane compound undergoing polycondensation reactions during heat curing of the composition, thereby forming a filler.
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AUXILIARY TOOL FOR INSERTING MEDICAL INSTRUMENT INTO LIVING BODY

(WO2005094663) 13.10.2005 A61B 1/00 JMS CO., LTD.
A tubular member (2) having an inner hole (2) is formed of a resin material. A thin plate material is spirally shaped along the circumferential direction of the tubular member (2) to construct a reinforcing member (3). The reinforcing member (3) is embedded in a circumferential wall (2a) of the tubular member (2). The tubular member (2) and the reinforcing member (3) are formed in a curved shape corresponding to a throat section (100). The tubular member (2) and the reinforcing member (3) are then inserted into the throat section (100) from a mouth cavity (102) and held in place. A medical instrument is guided to an esophagus (103) by the inner hole (2a) of the tubular member (2).
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NON-TOXIC DISINFECTANT CONTAINING A ISOPROPYL ALCOHOL AND SESAME OIL COMPOSITION WITH LEMON OIL AND MENTHOL

(WO2005094385) 13.10.2005 A61K 35/78 VIAMONTE, Manuel, Jr
A non-toxic mucosal disinfectant for topical application in the nose, skin, mouth and hard surfaces comprising a composition of 99.0% isopropyl alcohol of at least 24.0% by weight; sesame oil not exceeding 73.0% by weight and lemon oil of less than 3.0% by weight and menthol less than 1.0% by weight. All of the components are mixed homogeneously with the sesame oil supplementing and neutralizing the dehydrating effect of the alcohol.
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FITTING CAPS TO CONTAINERS

(WO2005092730) 06.10.2005 B65D 41/48 CARBONITE CORPORATION
The invention relates to a method of snap-fitting a lid to a container (2) including a neck (8), which defines the mouth of the container and on whose outer surface there is a downwardly directed shoulder (14). The lid also includes a closure plate (30, 32) connected to a depending peripheral skirt (18), connected to which by a resilient hinge (22) is a retaining flange (20). The method includes moving the lid and container relatively towards one another to bring the retaining flange (20) into contact with the upper edge of the neck (8), thereby causing the retaining flange (20) to rotate about the hinge (22) until the free end of the flange (20) moves past the shoulder (14). The retaining flange (20) is then rotated in the opposition direc...
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ORAL HEALTH CARE DRINK AND METHOD FOR REDUCING MALODORS

(WO2005092358) 06.10.2005 A61K 35/78 TASKER PRODUCTS IP HOLDINGS CORP.
An oral care composition and method of using. are provided for treating and preventing malodors or disease conditions of the oral cavity in warm-blooded animals, including humans. When applying an oral care effective amount of the oral care composition of the present invention to the mucosal tissue of the oral cavity, the gingival tissues of the oral cavity, and/or surface of the teeth. The application can be as a liquid for bathing, rinsing or gargling, or lather generated by brushing the teeth for a sufficient time. After rinsing, gargling or brushing, the composition of the present invention should be swallowed to achieve effective reduction of various organisms, diseases and malodors. An oral care effective amount can also prevent and h...
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CUP PACKAGE MADE OF A FIBRE-BASED MATERIAL

(WO2005090194) 29.09.2005 B65D 3/06 STORA ENSO OYJ
The invention relates to a cup package made of a fibre-based material, such as polymer-coated packaging board, comprising a cup (1) containing a packaged product (2) and a lid (6) closing the mouth of the cup. In accordance with the invention, the cup (1) has a collar (5) bent downwardly from the mouth of the cup and diverging from the cup skirt (3), and the lid (6) has a rim (8) oriented accordingly downwardly from the collar, the lid being fixed in position by heat-sealing between said collar and rim parts. For opening the package, the lid (6) can be equipped with a tear strip (11) surrounding its rim (8). In addition, the lid (6) may be nested with the cup (1), so that compression and friction between their opposite surfaces retain the l...
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DEVICE FOR SUBMENTAL ELECTROSTIMULATION OF THE SUPRAHYOIDAL MUSCLES

(WO2005089862) 29.09.2005 A61F 5/56 REDWEIKS, Ulrich
The invention relates to a device (1) for submental electrostimulation of muscles in the gums, tongue or floor of the mouth.The device (1) has an electrode for recessing a strip of the tongue (2), which is positioned underneath the tongue on a mucous covering the floor of the mouth (5). The lower side of the electrode (3) facing the floor of the mouth (5) is adapted to the contour of the floor of the mouth (5) and comprises two mirror-symmetrical areas (7,8) which are joined to each other by means of a retaining element (6) and which are electrically insulated in relation to each other. In order to control the two areas (7,8) of the electrode, they are respectively connected to an electric contact (9,10). The retaining element (6) is adjust...
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COMPOSITION FOR ORAL CAVITY

(WO2005089784) 29.09.2005 A61P 1/02 TOYO SHINYAKU CO., LTD.
A composition for the oral cavity which contains a pine bark extract extracted from the bark of a pine. The composition for the oral cavity can produce effects such as the effect of improving blood flow in the mouth and the effect of diminishing foul breath.
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COMPOSITION FOR TOOTHBRUSHING

(WO2005089703) 29.09.2005 A61K 7/16 KAO CORPORATION
A composition for toothbrushing which is highly effective in removing dental plaques and stains and gives an excellent use feeling. The composition for toothbrushing contains the following ingredients (A), (B), and (C): (A) 0.2-3 mass% powdery cellulose, (B) a surfactant, and (C) 10-30 mass% abrasive material.
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DISPENSER WITH SEALED DISPENSING VALVE UNIT

(WO2005087618) 22.09.2005 B65D 83/76 YONWOO CO., LTD.
A dispenser with a sealed dispensing valve unit is disclosed. The dispenser is secured to a mouth of a hermetic casing, and discharges contents through a center of an upper plate of a button. The dispenser includes an outlet hole (100) bored in a central portion of the button. An inclined inner surface defines a lower portion of the outlet hole, and a vertical inner surface extends from an upper end of the inclined inner surface to a predetermined height. The dispenser also includes a dispensing valve (200) having at a lower portion thereof an inclined outer surface to selectively come into contact with the inclined inner surface of the outlet hole due to operation of a pumping means, thus opening or closing the outlet hole. Further, a vert...
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DENTAL KIT FOR COATING TOOTH PLANES

(WO2005087179) 22.09.2005 A61C 19/06 SUN MEDICAL CO., LTD.
The invention aims at providing a dental coating kit which permits adjustment to a favorite color and safe application in a short time and can enhance the gloss of tooth planes without scaling the surface of a tooth. The aim is attained by producing a dental coating kit constituted of a case (I) filled with a coating composition (I) comprising (a1) an ethylenically unsaturated compound, (b1) a polymerization initiator, and (c1) a filler, and a case (II) filled with a coating composition (II) comprising (a2) an ethylenically unsaturated compound and, if necessary, (b2) a polymerization initiator and (c2) a filler, characterized in that the content (wt%) of the filler (c2) in the composition (II), [(c2)/[(a2) + (b2) + (c2)] 100, is lo...
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AN ATTACHMENT FOR A CLEANING APPLIANCE

(WO2005087072) 22.09.2005 A47L 9/00 DYSON TECHNOLOGY LIMITED
The invention provides an attachment (10, 60, 80) for a cleaning appliance (120) having a head (20, 62, 82) and a neck (30, 64, 84), the neck (30, 64, 84) being adapted to be connected to the mouth (50) of a wand (128) or hose (130) of the cleaning appliance (120). The neck (30, 64, 84) has a first portion (32, 66, 86) which, in use, lies alongside the mouth (50) of the wand or hose and a second portion (36, 68, 88) which, in use, is spaced away from the mouth (50) of the wand or hose. This arrangement provides a bleed air passageway (42) which allows atmospheric air to be bled into the hose or wand so as to reduce the suction at the main suction opening (24, 62a, 82d) of the attachment (10, 60, 80). It also provides an advantageous storage...
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SELF-CONTAINED DENTAL CARE DEVICE

(WO2005087047) 22.09.2005 A46B 11/00 PBL TECHNOLOGY LIMITED
A toothbrush (100), adapted for portable use and in a hygienic manner, comprises a brush and a folding handle (101). The handle (101) includes a depression (105) which accommodates the bristles (103) when the brush handle is folded closed. Means to transfer a desired amount of toothpaste into the depression (105) when required and hence on to the bristles (103) provides an amount of toothpaste ready for use. Various options for handling and dispensing toothpaste are disclosed, including a toothpaste/propellant mixture.
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REACTIVE OLIGOMERIC THIOL AND ENE MATERIALS AS DENTAL RESTORATIVE MIXTURES

(WO2005086911) 22.09.2005 A61C 5/00 THE REGENTS OF THE UNIVERSITY OF COLORADO
The present invention provides a dental composition comprising a curable blend of one or more polythiol compounds and one or more polyvinyl compounds; where one or both compounds are oligomers. In one aspect, the polythiol compounds are polythiol oligomers formed by prepolymerization of polyvinyl monomers in the presence of an excess of polythiol monomers. In another aspect, the polyvinyl compounds are polyvinyl oligomers formed by prepolymerization of polythiol monomers in the presence of an excess of polyvinyl monomers. The dental composition may further comprise one or more fillers or photoinitiators known in the art. The invention also comprises methods of making a dental prosthesis comprising the composition described above. Use of the...
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SYSTEM AND METHOD FOR PROVIDING CUSTOMIZED PRODCUTS AND REFERRALS

(WO2005086820) 22.09.2005 G06Q 30/00 DISCUS DENTAL IMPRESSIONS, INC.
A system and method for providing a consumer with dental services and products from a retail location, such as, for example, a local shopping mall. The dental service or product may include a teeth whitening product or service. The retail location is operated by a registered dental assistant or hygienist under supervision of a licensed off-site dentist. The dental assistant or hygienist uses an intra-oral camera and/or x-ray machine to take images of the customers teeth and/or mouth. The images are transmitted to the off-site dentist over a data communications network, The off-site dentist evaluates the images and approves or denies a request for a particular dental service or product. If approved, the product or service is dispensed...
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BIOCOMPATIBLE POLYMER COMPOSITIONS FOR DUAL OR MULTISTAGED CURING

(WO2005085312) 15.09.2005 A61K 6/00 COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
The present invention provides a biocompatible polymer composition for use in biomedical applications comprising a base molecule, a linker molecule and at least one initiator compound, said base molecule having at least two differing functionalities, and said linker molecule having a functionality reactive with at least one functionality of said base molecule, the first of said at least two functionalities of said base molecule enabling a first curing stage of said polymer composition by reaction with said linker molecule, and the second and any further functionality of said base molecule enabling second and further curing stages of said polymer composition, said first, second and any further curing stages being capable of activation simult...
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SUSTAINED-RELEASE COMPOSITION FOR ORAL CAVITY

(WO2005084703) 15.09.2005 A61K 9/22 NRL PHARMA, INC.
It is intended to provide a sustained-release composition for the oral cavity which can be stuck to the oral cavity, is excellent in effect of sustainedly releasing a drug so as to topically exert the effect of the active ingredient over a long period of time and efficiently exert the preventive and therapeutic effects against various diseases in the oral cavity, gives little unpleasant feeling in the mouth even in prolonged use, remains highly safe with little side effects and can be produced by the direct tabletting method; and a process for producing the same. Namely, a lactoferrin-containing sustained-release composition for oral cavity characterized by containing a pectin material.
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FLAVOURED TOOTHPASTE COMPOSITION

(WO2005084628) 15.09.2005 A61K 8/34 PAGLIERI SELL SYSTEM S.P.A.
This invention relates to a flavoured toothpaste composition wherein the flavour comprises at least one refreshing agent selected from the group consisting of menthol and spearmint in a percentage amount by weight in the range from 25% to 70% and at least one essential oil of plant origin, wherein if said at least one essential oil is selected from the group consisting of essential oil parsley, rose absolute, geranium, cloves or cinnamon, then the percentage by weight of said essential oil in the flavour will be between 0.01% and 1%; if said at least one essential oil is selected from the group consisting of essential oil of star anise, mandarin, eucalyptus, sage and lime then the percentage by weight of said essential oil in the flavour wi...
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ALCOHOL-FREE CHLORHEXIDINE COMPOSITIONS

(WO2005084627) 15.09.2005 A61K 8/43 UNIVERSITY OF IOWA RESEARCH FOUNDATION
The invention provides alcohol-free chlorhexidine compositions, improved methods for preparing colloidal chlorhexidine containing compositions, and methods for promoting an antibacterial effect comprising administering chlorhexidine compositions to the mouth of an animal. The invention also provides an improved chlorhexidine composition comprising a flavoring agent (e.g. a raspberry flavoring agent) that increases the antibacterial activity of the composition.
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CLEANING DEVICE FOR PERSONAL HYGIENE

(WO2005084507) 15.09.2005 A47K 7/00 YU, Shihkuei
A cleaning device for personal hygiene,which includes an elastic bottle (l) and a nozzle tube (2) connected to the mouth (11) of the elastic bottle, and a cleaning head (3) on the end of the nozzle tube (2), the portion near the cleaning head (3) of the nozzle tube (2) is bent to one side, similar to a folded angle shape, a smooth simicircle projection (31) is on the surface of the cleaning head (2),there are water spraying holes (32) on the two sides of the projection of the cleaning head's surface.The invention is easy to use since the configuration of the nozzle tube is designed for the request of human engineering, and has function to wipe and wash anus. The configuration of the cleaning head of the invention make it can not only to jet...
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PARTICULATE FLAVOURING COMPOSITION

(WO2005084458) 15.09.2005 A23L 1/00 QUEST INTERNATIONAL B.V.
The present invention relates to particulate compositions comprising controlled release particles wherein discrete elements of flavouring-containing fat are dispersed in a gelatine matrix, said particles containing: 0.1-40 wt%, preferably 5-30 wt% of flavouring; 10-70 wt%, preferably 20-50 wt% of gelatine; and 0.1-75 wt%, preferably 5-50 wt% of fat, the fat having a melting point of at least 35 C; and said particles having a volume weighted average diameter of 50 - 1500 m. The particulate composition according to the present invention will release the flavouring comprised therein under specific conditions e.g. under the influence of shear forces, heat and/or moisture. The release rate upon consumption can be affected by varying ...
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USE OF QUERCETIN AND RESVERATROL TO TREAT AND PREVENT ORAL CANCER

(WO2005082407) 09.09.2005 A61K 39/00 MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
A pharmaceutical composition comprising a topically effective amount of quercetin and a topically effective amount of resveratrol in a pharmaceutically acceptable carrier is provided. A method of treating oral cancer in a subject is provided, comprising topically administering to the mouth of the subject a topically effective amount of quercetin and a topically effective amount of resveratrol in a pharmaceutically acceptable carrier. A method of preventing oral cancer in a subject is provided, comprising topically administering to the mouth of the subject a topically effective amount of quercetin and a topically effective amount of resveratrol in a pharmaceutically acceptable carrier.
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MANGANESE AND IRON BASED COMPOUNDS FOR ELASTOGENESIS AND CONNECTIVE TISSUE TREATMENT

(WO2005082386) 09.09.2005 A61K 33/26 HUMAN MATRIX SCIENCES, LLC
The present invention describes therapeutic compositions comprising one or more minerals, including trivalent iron, divalent manganese and salts thereof, suitable in facilitating synthesis and deposition of connective tissue matrix, particularly rich of elastin and collagen, and mitogenic potential in human dermal fibroblasts. It also describes the phenomenon in which stimulation of elastogenesis by arterial SMC associates with a net decrease in proliferation of these cell types. The present invention also describes methods of treatment of human skin fibroblasts and arterial smooth muscle cells. The therapeutic compositions of the present invention comprise one or more of trivalent iron or divalent manganese or salts thereof and may be comb...
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TOOTH PASTE WITH BOWMAN-BIRK INHIBITOR FOR SMOKERS HEALTH

(WO2005082324) 09.09.2005 A61Q 11/00 SHAH, Amit, Navnit
A tooth paste containing bowman birk inhibitor along with muco-adhesive agent, matrix former, abrasive, humectants/sweetener/mouth feelers, low calorie sweetener, suitable preservative/s, permitted colours, foaming agents, flavor/s and purified water for smoker's health. The muco-adhesive agent/s embedded BBI is uniformly distributed with oral mucosal uptake promoting agent, cleanser and solubiliser/foaming agent in a gel matrix constituted by specialized silica. This helps in regeneration of the mucosal cells. This toothpaste consists of natural mucosal uptake promoting agent, which upon dilution with salivary fluid or hydrophilic or water containing liquid or water leads to emulsification. The emulsified globules of BBI have very high sur...
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HERNIA NET FOR TREATING INGUINAL OR HIATUS HERNIAS

(WO2005082274) 09.09.2005 A61F 2/00 GFE MEDIZINTECHNIK GMBH
The invention relates to a hernia net for treating, in particular, inguinal or hiatus hernias. Said net comprises a base plate (1) consisting of a layer of flexible net material, a passage (3) in the base plate (1) for a body canal, in particular for the spermatic cord or the oesophagus, an insertion slit (5) between the contour (4, 9) of the base plate (1) and the passage (3) for introducing the body canal into the passage (3) and a sewing bridge (7), which lies in the vicinity of the mouth (6) of the insertion slot (5), can be folded over the insertion slot (5) and which can be sewn to the net material of the base plate (1) on both sides of said slot.
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UNIVERSAL TRAY DESIGN HAVING ANATOMICAL FEATURES TO ENHANCE FIT

(WO2005082266) 09.09.2005 A61C 5/00 ULTRADENT PRODUCTS, INC.
A tray-shaped dental treatment device (300) includes a moisture-resistant barrier layer (312) having a front side wall (302) and a bottom wall (304), and a dental treatment composition. In addition, the tray-shaped dental treatment device (300) includes at least one of the following anatomical features to enhance the fit of the device: (1) the bottom wall includes a plurality of cuts (306, 308) positioned to help the bottom wall (304) better conform to abrupt changes in the diameters of a person's teeth where the bicuspids and canines meet, or (2) the bottom wall includes at least one V-shaped or U-shaped indentation (3 10) configured to be inserted into the depression typically found along the top surfaces of a person's molars, or (3) the ...
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HANGOVER REMEDY AND ALCOHOL ABATEMENT COMPOSITION

(WO2005082069) 09.09.2005 A01N 65/00 TASKER PRODUCTS IP HOLDINGS CORP.
An anti-intoxication composition and method of making and using are provided for treating and preventing drinkers remorse and other toxic effects of excessive alcohol consumption by humans. The anti-intoxication composition is an acidic mixture containing sweeteners, flavoring agents, food additives and a processed mixture of metallic salts, sulfuric acid, ammonium sulfate and water. When the anti-intoxication composition is ingested, it promotes the beneficial metabolism of alcohol, primarily ethanol, in the body. The beneficial metabolism results in the conversion of alcohol to amino acids and eliminates the toxic reactions of a hangover, including, but not limited to, a pounding headache, nausea, dry mouth, shaking hands, hypersen...
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DENTAL BLEACHING DEVICES HAVING A PROTECTIVE ADHESIVE REGION

(WO2005081656) 09.09.2005 A61K 7/16 ULTRADENT PRODUCTS, INC.
Dental bleaching devices (10) in the shape of a dental tray, strip or patch include a barrier layer (18), a dental bleaching composition (28), and a protective adhesive composition (24, 26) that protects a person's gums from the dental bleaching composition during use. The barrier layer (18) protects the bleaching and protective adhesive compositions (24, 26, 28) ftom saliva or moisture during use. The dental bleaching composition is positioned (28) so as to contact a person's tooth surfaces when the bleaching device (10) is in use. The protective adhesive composition (24, 26) is positioned so as to shield a person's gums from the bleaching composition when the bleaching device is in use. The dental bleaching composition (28) and protective...
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MACROPOROUS, RESORBABLE AND INJECTIBLE CALCIUM PHOSPHATE-BASED CEMENTS (MCPC) FOR BONE REPAIR, AUGMENTATION, REGENERATION, AND OSTEOPOROSIS TREATMENT

(WO2005077049) 25.08.2005 C04B 12/02 NEW YORK UNIVERSITY
A composition and method for producing interconnective macroporous, resorbable and injectable calcium phosphate-based cements (MICPs). The composition of the invention sets to poorly crystalline apatitic calcium phosphate after mixing a powder component and an aqueous solution. The multiphasic calcium phosphate components in the cement resorb at different rates allowing he timely replacement by new bone. The interconnected macroporosity in the cement allows for vascularization, entrapment of growth factors, cell colonization and tissue ingrowth. This MICPC can be used for dental and medical applications relating to bone repair, augmentation, reconstruction, regeneration, and osteoporosis treatment, and also for drug delivery, and as scaffol...
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OPACITY AND COLOR CHANGE POLYMERIZABLE DENTAL MATERIALS

(WO2005074863) 18.08.2005 A61K 6/00 BISCO, INC.
Polymerizable compositions are described containing colored polymerization indicators which confer a visible color on the unpolymerized compositions. Upon polymerization, the compositions exhibit reduced or eliminated color. The compositions can also change their opacity during polymerization. The compositions provide easy visual differentiation between the unpolymerized compositions and substrates on which the compositions are placed. The compositions are useful in clinical and laboratory applications such as those involving teeth, dental implants, orthodontic materials, artificial teeth and bones.
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ADHESIVE COMPOSITION FOR ENAMEL

(WO2005074862) 18.08.2005 A61K 6/00 SUN MEDICAL CO., LTD.
An adhesive resin cement composition for enamel which is excellent in bonding performance and mechanical properties and has aestheticity even when neither a primer nor an adhesive is applied in bonding to enamel. It is a photocurable dental adhesive composition for enamel which comprises (A) a radical-polymerizable monomer having an acid group and having a structure represented by the following formula (1): CH2=CR1-COO-R2-OCO-R3-COOH (1) (wherein R1 represents hydrogen or CH3; and R2 and R3 each independently represents a divalent inert group consisting mainly of carbon and hydrogen), (B) a monofunctional radical-polymerizable monomer having a molecular weight of 220 or lower and a boiling point of 60 C/10 mmHg or higher, (C) an aromat...
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RUSSIAN CIGARETTE ( PAPIROSY) CASING

(WO2005074696) 18.08.2005 A24D 1/04 BILIVITIN, Yuriy Sergeyevich
The invention relates to a sleeve for producing a Russian cigarette by a smoker himself or in the industrial mass-production. The inventive Russian cigarette sleeve consists of a hollow mouth end (1) and a hollow envelop (2) which is connected thereto and whose at least one part of the cavity (4) contains a smoking material and is provided with a separating smoke-permselective membrane which is arranged in such a way that it is possible to separate the part of the cavity (3) of the mouth end (1) from the part of the cavity (4) of the envelop (2) containing the smoking material and to overlap at least one part of the cross section of the cavity (3) of the mouth end (1). Said sleeve makes it possible to prevent the penetration of the particle...
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CHEESE PRODUCTS

(WO2005074694) 18.08.2005 A23C 19/032 DANISCO A/S
The present invention relates to a composition and a method of preparing cheese products with a suitable moisture level. The cheese products that have been formed using the composition are characterised with an improve at least one of aroma, flavour, mildness, consistency, texture, syneresis, body, mouth feel, firmness, viscosity, gel fracture, wheying off, structure and/or organoleptic properties, nutrition and/or health benefits. In particular, the present invention provides a composition comprising a starter acidification micro-organism and an EPS fermentation culture comprising a viable micro-organism an enzyme produced by said micro-organism and an exopolysaccharide (EPS) produced by the activity of said enzyme.
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PIT FURNACE CLOSING SYSTEM

(WO2005073413) 11.08.2005 C21D 9/70 NAPOLI, Rodolfo
Pit furnace closing system, comprising the use of two beams (2) and several square iron bars (4) laid across the border of the furnace (3) and supported over said beams (2), and pieces of cloth wrap for high temperature are used for closing the furnace of a species box in a stainless steel screen was further developed, folded and having a ring, and filled in with remains of wraps, or even a biparted lid (19) in a thin plate with wraps fixed to it and a cut for the upper part of the supporting device of the parts to pass, which is the cage-like one, and suspended inside the furnace (3) and supported in the two beams (2), not resting on the floor of the furnace (3), and said furnace (3) has thermopairs, which may be in contact w...
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PROTEIN WITH ACTIVITY OF HYDROLYZING DEXTRAN, STARCH, MUTAN, INULIN AND LEVAN, GENE ENCODING THE SAME, CELL EXPRESSING THE SAME, AND PRODUCTION METHOD THEREOF

(WO2005073368) 11.08.2005 C12N 9/24 LIFENZA CO., LTD.
Disclosed is an enzyme, having the amino acid sequence of SEQ. ID. No. 1 with the activity of hydrolyzing dextran, starch, mutan, inulin and levan, a gene encoding the enzyme, and a transformed cell expressing the gene. Also disclosed is a method of producing an enzyme capable of degrading dextran, starch, mutan, inulin and levan, which comprises culturing the cell, expressing the enzyme in the cell and purifying the enzyme. A composition comprising the enzyme is provided for removing dextran or polysaccharide contaminants during sugar production. With such degradation activity, the enzyme not only finds various applications in the dental care industry, including anti-plaque compositions and mouthwashes, but is also useful in removing dextr...
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ORAL CARE COMPOSITIONS COMPRISING INCREASED BIOAVAILABLE LEVELS OF QUATERNARY AMMONIUM ANTIMICROBIALS

(WO2005072693) 11.08.2005 A61K 8/41 THE PROCTER &GAMBLE COMPANY
Disclosed are oral care compositions, including therapeutic rinses, especially mouthrinses and methods of use to provide significantly enhanced antimicrobial activity, thereby reducing oral bacteria and promoting overall oral health. The present compositions are formulated to deliver increased bioavailable levels of cationic antimicrobials, particularly quaternary ammonium compounds such as cetylpyridinium chloride (CPC) and are useful for preventing and treating diseases or conditions of the oral cavity including dental plaque, caries, gingivitis, periodontal disease and breath malodor. The present compositions are formulated to be essentially free of anionic, nonionic or amphoteric surfactants, which have been found to have a negative eff...
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DENTAL-BLEACHING COMPOSITIONS AND METHODS WITH REDUCED PEROXIDE CONCENTRATION

(WO2005072692) 11.08.2005 A61K 8/22 COLGATE-PALMOLIVE COMPANY
A peroxide containing dual component dentifrice composition providing enhanced whitening efficacy and minimal gingival irritation and tooth sensitivity, the composition being comprised of a separately maintained first aqueous dentifrice component containing a peroxide compound and an abrasive system compatible with the peroxide and a second aqueous dentifrice component containing a desensitizing compound and an abrasive that is incompatible with peroxide compound whereby when the components are mixed and combined for the first time and exposed to the surface of teeth, an enhanced whitening effect is obtained with minimal tooth sensitivity and gum irritation.
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LIGHT-BASED TOOTHBRUSH

(WO2005072642) 11.08.2005 A61B 5/00 COLGATE-PALMOLIVE COMPANY
A toothbrush that uses light to deliver an oral care benefit such as the detection of plaque or the whitening of teeth. In one embodiment, dye is incorporated in a carrier that attaches to residual plaque on the tooth surface and is activated by the presence of ultraviolet radiation to create a fluorescent effect that would indicate the presence of plaque remaining on the teeth. In another embodiment, a toothpaste formulation contains ultraviolet brighteners as a whitening ingredient that have a whitening or bleaching effect when in contact with ultraviolet radiation. The activation of the brighteners preferably occurs through the use of a toothbrush having a UV source. In yet another embodiment, a toothpaste formulation contains an oxidizi...
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DENTAL FLOSS WITH ANTI-MICROBIAL AGENT

(WO2005072641) 11.08.2005 A61C 15/04 LG HOUSEHOLD &HEALTH CARE LTD.
Disclosed is an antimicrobial dental floss for cleaning teeth including xanthorrhizol as an effective component. The antimicrobial dental floss for cleaning teeth of the present invention can not only remove food particles and dental plaques present in teeth like a conventional dental floss, but also have antimicrobial activity against causative microorganisms of caries and periodontal disease in oral cavity. Therefore, the antimicrobial dental floss of the present invention can prevent and relieve caries and periodontal disease, and eliminate halitosis.
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TOOTHBRUSH COMPRISING RESERVOIR FOR TOOTHPASTE

(WO2005072559) 11.08.2005 A46B 11/00 RUSH BRUSH
The present invention provides a toothbrush comprising a reservoir in fluid communication with a toothbrush head (30) comprising an elevated element (35) arranged with apertures (32) on a surface of said elevated element (35) facing inwards towards a cavity (34) formed between the elevated element (35) and a bottom surface comprising bristle of said toothbrush head (30).
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TOOTHBRUSH FOR ANIMAL

(WO2005072519) 11.08.2005 A01K 13/00 MORIYAMA, Toshio
A toothbrush for animals, especially dogs, capable of cleaning the teeth, gum and mouth by utilizing an ultrasonic wave. The toothbrush comprises a toothbrush body (2) formed like a rod so that an animal holds it in its mouth, and an ultrasonic vibration generating means provided in the toothbrush body. The toothbrush body (2) has a part (3) held by the animal in the mouth, and a grip part (4) which a person grips the toothbrush body (2). The ultrasonic wave generating means provided in the toothbrush body causes cavitation in the saliva and liquefied dentifrice in the mouth to destroy cilia of dental plaque bacteria and insoluble glucan adhering to the surface of teeth and to remove dental plaque by unchaining, thus reducing infection of t...
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LACTOFERRIN-TREATED FILAMENT MATERIALS

(WO2005072261) 11.08.2005 A01N 25/34 NAIDU, A., Satyanarayan
Disclosed is a filament composition having a surface for reducing microbial contamination having a surface for reducing microbial contamination comprising a filament material, such as a dental floss or a suture material, and lactoferrin.
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PET WITH STRESS CRACKING RESISTANCE, PREFORM AND CONTAINER MADE THEREWITH AND METHOD

(WO2005070996) 04.08.2005 C08G 63/00 THE COCA-COLA COMPANY
A preform comprising an open-ended mouth forming portion, an intermediate body forming portion, and a closed base forming portion comprising a stress cracking resistant polyester composition comprising poly(ethylene terephthalate) based resin and an impact modifier. The preform is blow molded to form a corresponding container. Polyester compositions and methods are also disclosed. The impact modifier improves the stress cracking resistance of low IV PET such that the containers perform similar to those made of high IV PET.
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WHEEL CONVEYOR

(WO2005070792) 04.08.2005 B65G 39/12 YAZAKI INDUSTRIAL CHEMICAL CO.,LTD.
A wheel conveyor formed by installing a wheel assembly having wheels and support plates disposed on both sides thereof and rotatably supporting the axles of the wheels in the grooves of frame materials, easily disassembled and cleaned, and having vibration damping function and dust collecting function. In the wheel assembly (2), the wheels (5) comprise axle pins (6), pin holes (8) are formed in the support plates (7), and the axle pins (6) are inserted into the pin holes (8) and rotatably supported on the pin holes. The shape of the frame material (4) in cross section is such that a first groove-shaped part (4b) formed continuously with a lip part (4a) supports the support plate (7) movably in the longitudinal direction, and a bottom part g...
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IONTOPHORETIC DEVICES AND METHODS

(WO2005070134) 04.08.2005 A61N 1/30 TAPPER, Robert
A system including methods, apparatus, components and charged chemicals for control of ions, molecules or electrons whereby charged membranes (11), testing devices (100), electrode patch structures (10) and the like utilize features of the invention for control of flow in a wide variety of new and improved medical, testing, cosmetic, personal care, flow delivery applications and the like.
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SPECIFIC INSTRUMENT FOR GENERAL ORAL HYGIENIC CLEANING

(WO2005069715) 04.08.2005 A46B 15/00 GOMES, Ccero Moreira
Specific Instrument for general oral hygienic cleaning describes the present patent of the field technician of products for general oral hygiene, as a special instrument (1) for general oral hygienic cleaning that, according to its characteristics, has as principle to contribute to a proper and specific structure in resin with memory of high resistance or similar that integrated in a unique body the structures of a tooth brush (3), a cleaner of tongue (4) and a dental floss case (5), making possible the formation of a set unique, complete and safe similar to a traditional tooth brush, whose form and disposal internal and external are perfectly adapted to oral cant of the users, along with a perfect preservation in the most diverse places in...
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DENTIFRICE COMPOSITIONS

(WO2005067876) 28.07.2005 A61K 8/25 GLAXO GROUP LIMITED
A dentifrice composition comprising an abrasive system comprising at least one abrasive silica which may be selected from a first silica having a Radioactive Dental Abrasion (RDA) in the range 30 to 150 and a second silica having an RDA in the range 100 to 300, and a crystalline aluminosilicate having an average crystallite size below 0.2 m plus an orally acceptable carrier. The content by weight of the first silica being greater than that of the second silica and the RDA of the second silica being greater than that of first silica.
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OXIDATIVE TREATMENT AGENT, PARTICULARLY IN THE FORM OF A TRANSPARENT GEL

(WO2005067874) 28.07.2005 A61K 8/04 WELLA AKTIENGESELLSCHAFT
Disclosed is a preferably clear or transparent gel-type agent for performing oxidative treatments in different fields of application, e.g. in cosmetics, dental technology, pharmaceutics, and cleaning agents. The inventive agent is particularly well suited for use in cosmetic hair treatments such as bleaching, oxidative hair dyeing, and permanent changes of hair shape. The inventive agent contains a mixture of an oxidant, at least one peroxide stabilizer, at least one specific polymer thickener, and water or an aqueous solvent.
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DENTAL OR SURGICAL ADHESIVE AND POLYMERIZATION INITIATOR COMPOSITION THEREFOR

(WO2005067866) 28.07.2005 A61L 24/00 SUN MEDICAL CO., LTD.
A polymerization initiator composition which, even when brought into contact with paper or the like in air, neither scorches nor ignites it and which imparts high polymerizability to a polymerizable composition to enable it to cure in a short time; and an adhesive composition containing the polymerization initiator composition. The polymerization initiator composition comprises 100 parts by weight of an organoboron compound (A) such as a trialkylboron, alkoxyalkylboron, dialkylborane, monocyclo- or bicyclocompound having a boron atom as a heteroatom, or partially oxidized trialkylboron, 5 to 40 parts by weight of an aprotic solvent (B) having a boiling point of 50 to 120C, and 0.2 to 5 parts by weight of an alcohol (C) having a boiling...
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THE METHOD FOR PRODUCING HIGHLY FUNCTIONAL SOY JUICE WITH DIETARY FIBER BY USING HIGHLY PURE, FUNCTIONAL, FULL-FAT ACTIVATED, RAW SOYBEAN FLOUR AS ITS RAW MATERIAL, BASED ON NATURAL QUALITY-EQUALIZATION METHOD; AND THE EQUIPMENT FOR PRODUCING SUCH SOY JUICE

(WO2005067400) 28.07.2005 A23L 2/38 SOYZEN CO., LTD
Highly pure functional full fat activated raw soybean flour is new functional food material with nutritional and metabolical characteristics. In this design, it is mixed with softened water (hardness 0) and additives (polysaccharide trehalose, green teat flour, chitosan, bamboo salt) at the ratio of 1:12:0.2~0.5. Due to its composition (40% protein, 20% fat and 25% carbohydrates), it is not well mixed with softened water. This problem can be eliminated by multi level high speed agitation and high pressure quality-equalization processes making soybean juice supernatant finer. This design enables the production of highly functional soybean juice with dietary fiber with smooth mouth feeling and removes fishy smell. In addition, it is exp...
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VALVE FOR THE CLOCKED FILLING OF PRODUCTS FROM A STORAGE TANK TO A PACKAGING CONTAINER

(WO2005066527) 21.07.2005 B65B 3/32 HASSIA VERPACKUNGSMASCHINEN GMBH
The invention relates to a valve for the clocked filling of liquid to flowing-pasty products from a storage tank (1) to a packaging container. Said products are transported in a correspondingly clocked manner via the filling station of a packaging machine. Said valve comprises a product conveyor path which extends from the storage tank (1) through a dosing pump (2) to an output mouth piece (3) and said product conveyor path is provided with a closing and opening valve (V) which can be adjusted in a clocked manner. Said valve is formed by a slider (8) which can be displaced in a sealed manner between plates (6,7) and the plates (6,7) contain channels (9, 10) which are aligned in relation to each other from the dosing pump (2) to the mouth pi...
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DENTAL ABRASIVE SYSTEM

(WO2005065636) 21.07.2005 A61K 8/24 INEOS SILICAS LIMITED
An abrasive system for use in high cleaning, controlled abrasivity dentifrice compositions comprises a combination of a crystalline aluminosilicate having an average crystallite size below 1.0 m and a water-soluble, orally acceptable calcium sequestering agent. The crystalline aluminosilicate may have an RDA of less than 120 and a calcium binding capacity of at least 100 mg CaO per gram of anhydrous aluminosilicate. The water-soluble, orally acceptable calcium sequestering agent may be sodium tripolyphosphate.
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DENTAL ABRASIVE SYSTEM

(WO2005065634) 21.07.2005 A61K 8/25 INEOS SILICAS LIMITED
An abrasive system for use in high cleaning, controlled abrasivity dentifrice compositions comprises at least one abrasive silica which may be selected from a first silica having a Radioactive Dental Abrasion (RDA) in the range 30 to 150 and a second silica an RDA in the range 100 to 300, and a crystalline aluminosilicate having an average crystallite size below 0.2 m. The content by weight of the first silica is usually greater than that of the second silica and the RDA of the second silica being greater than that of the first silica.
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COSMETIC AND HYGIENE PRODUCTS CONTAINING DEUTERIUM-DEPLETED WATER

(WO2005065631) 21.07.2005 A61Q 11/00 NEDELCU, Ioan
The present invention relates to cosmetic and hygiene products with application in cosmetology for maintaining and improving the health condition by balancing and ameliorating the cosmetological status, to a process for obtaining and using the same. According to the invention, the cosmetic and hygiene products comprise 5 ... 96% by weight of deuterium-depleted water (ASD), wherein the deuterium content is in the range of 2 ... 80 ppm, in association with pharmacologically acceptable excipients and are formulated as lotions, sprays, gels, creams, emulsions, mouth care water, dentifrice, soaps, masks, shampoos.
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METHOD FOR MAKING A DENTAL APPLIANCE FROM AN UNCURED, SELF SUPPORTING, HARDENA BLE ORGANIC COMPOSITION

(WO2005065572) 21.07.2005 A61C 13/00 3M INNOVATIVE PROPERTIES COMPANY
The invention features a dental mill blank constructed from an uncured, self-supporting, hardenable organic composition. The invention also provides a method of making a dental appliance. The method involves machining an uncured dental mill blank into an uncured shaped article and then at least partially curing the shaped article. The shaped article may be cured in multiple steps with or without additional machining steps in between the curing steps.
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ONE-PART SELF-ETCHING, SELF-PRIMING DENTAL ADHESIVE COMPOSITION

(WO2005063778) 14.07.2005 A61K 6/00 DENTSPLY DETREY GMBH
One-part self-etching, self-priming dental adhesive composition having a pH of at most 2, which comprises (a) a polymerizable acidic phosphoric acid ester monomer (b) one or more polymerisable acidic monomers (c) a polymerizable N-substituted alkylacrylic or acrylic acid amide monomer; (d) optionally an organic and/or inorganic acid; (e) an organic water soluble solvent and/or water; and (f) polymerization initiator, inhibitor and stabilizer.
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HERBAL ORO-DENTAL CARE COMPOSITION AND PROCESS FOR PREPARING THE SAME

(WO2005063186) 14.07.2005 A61K 7/26 COUNCIL OF SCIENTIFIC &INDUSTRIAL RESEARCH
This invention relates to novel dental compositions and methods for preventing dental plaque and caries formation and generally for inhibiting tooth decay and brightening/whitening teeth/mouth ulcer. The compositions of this invention comprise herbs such as Citrus karna raf., Zanthoxylum armatum D.C. and Azadirachta indica A. Juss. there of which can be combined with pharmaceutically acceptable carriers or diluents to be administered in the form of conventional dental compositions. The compositions of the present invention also preferably contain Mint.
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COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING PLAQUE AND/OR GINGIVITIS USING A BIOACTIVE GLASS CONTAINING DENTIFRICE

(WO2005063185) 14.07.2005 A61K 7/16 NOVAMIN TECHNOLOGY INC.
Methods and compositions for the prevention and/or reduction of plaque, plaque build-up and/or gingivitis are provided. Bioactive glass compositions are provided which prevent or reduce plaque, plaque build-up and/or gingivitis through the use of low levels of small bioactive glass particles in amounts from about 0.25 to about 10% by weight in non-aqueous formulations. The resulting non-aqueous compositions are effective in dentifrice products and are stable and pass ISO (International Organization for Standardization) standards. Moreover, these bioactive glass containing non-aqueous compositions have unexpectedly high levels of antimicrobial activity against oral pathogens.
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DENTAL ROOT CANAL FILLING MATERIAL

(WO2005063171) 14.07.2005 A61K 6/00 DENTSPLY DETREY GMBH
A dental root canal sealing composition curable in the absence of a polymerisation initiator, which comprises (i) an amino terminated prepolymer having a viscosity at 23C of less than 100 Pas. (ii) a compound capable of undergoing polyaddition with the aminoterminated prepolymer (i); (iii) 40 to 85 wt.-% of a filler for providing a minimum radioopacity of at least 3mm/mm Al.
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ION EXCHANGE DENTAL DEVICE AND METHOD

(WO2005062710) 14.07.2005 A61C 3/00 FLUORINEX ACTIVE LTD.
A device and method for enhanced fluoride uptake by are provided herein. The method includes pre-treating the teeth with a metal salt solution, and then treating the teeth with a fluoride gel and electrical current. A pretreatment tray includes a sponge for absorbing metal salt solution and for prevention of leaking thereof into the mouth. The treatment device includes at least two electrodes, and an applicator for applying an ionizable fluoride substance to the teeth. A current flow is provided, which flow runs through the device and external to the body of the individual.
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DEVICE FOR PRODUCING A SPUN THREAD FROM A STAPLE FIBRE COMPOSITE

(WO2005061765) 07.07.2005 D01H 1/115 MASCHINENFABRIK RIETER AG
The invention relates to a device for producing a spun thread, comprising a drafting system that contains a pair of delivery rollers (5, 6) and an air-jet assembly (4) situated downstream of said rollers. An eddy chamber (9) comprising an exhaust-air channel (12) is located in the air-jet assembly. The device is also equipped with at least one cleaning channel (17), which communicates with the delivery roller pair (5, 6) by means of a suction opening. The cleaning channel (17) is connected to the exhaust-air channel (12) by means of a mouth (20). In addition, a compressed air opening (22) of an injection channel (21), which can reinforce the negative pressure of the exhaust-air channel if required, is positioned in the vicinity of the mouth...
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ONE-PACK TYPE ADHESIVE COMPOSITION FOR DENTAL USE

(WO2005060920) 07.07.2005 A61K 6/00 KURARAY MEDICAL INC.
A one-pact type adhesive composition for dental use which is obtained by compounding as essential ingredients a hydrophobic polymerizable monomer (a) having an acid group, a water-soluble polymerizable monomer (b), water (c), a photopolymerization initiator (d), an aromatic tertiary amine (e) having an electron-attracting group, a crosslinking polymerizable monomer (f), and a basic compound (g) which reacts with part of the hydrophobic polymerizable monomer (a) having an acid group to generate a water-soluble salt. The composition has excellent bonding strength in the bonding of a tooth, especially enamel or dentine, to a dental repairing material, especially a resinous material, and has excellent storage stability. Because the composition ...
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COMPOSITIONS AND METHODS OF DELIVERING BLEACHING AGENTS TO TEETH

(WO2005058268) 30.06.2005 A61K 8/22 THE PROCTER &GAMBLE COMPANY
The present invention relates to compositions and methods of whitening teeth of a subject in need thereof, by applying a safe and effective amount of a composition to a plurality of teeth, the composition comprising: a. a safe and effective amount of a bleaching agent; b. a safe and effective amount of a water insoluble solid phase; c. a safe and effective amount of a water soluble liquid phase; wherein the ratio of the water insoluble solid phase to water soluble liquid phase is from about 1:4 to about 4:1; wherein the composition is applied for a sufficient period of time to achieve whitening; and wherein in one embodiment the composition has a Whitening Index of from about 0.5 to about 4. The composition comprises a hydrophobically modif...
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ORAL CARE DELIVERY SYSTEM COMPRISING A BLEACHING AGENT

(WO2005058266) 30.06.2005 A61K 8/22 THE PROCTER &GAMBLE COMPANY
Oral care delivery system comprising an integral carrier e.g. a strip material, dental tray or sponge material and a composition for whitening teeth of a subject in need comprising: a. a safe and effective amount of a bleaching agent; b. a safe and effective amount of a water insoluble solid phase; c. a safe and effective amount of a water soluble liquid phase; wherein the ratio of the water insoluble solid phase to the water soluble liquid phase is from about 1:4 to about 4:1. The composition is applied for a sufficient period of time to achieve whitening; the composition may have Whitening Index of from about 0.5 to about 4. The composition optionally comprises a hydrophobically modified polymer.
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ADJUSTABLE SYSTEM FOR BONDED COMPOSITE DENTISTRY

(WO2005058179) 30.06.2005 A61C 13/225 DELMONICO, Frank, E.
A dental bridge and a method of assembling a dental bridge. An adjustable system for bonded composites may generally include a ladder supporting a truss in one of multiple relative positions therewith. The ladder generally includes opposing rails connected by a plurality of rungs. The plurality of rungs are spaced along the rails to define a plurality of openings between adjacent rungs. The truss generally includes a metal strip having a plurality of upstanding projections. The projections are correspondingly spaced with the openings defined in the ladder to allow the truss to engage the ladder in a plurality of relative configurations. The combination of the ladder and truss may also provides a torsionally rigid and substantially stiff ass...
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CLOSURE FOR RECEIVING FLEXIBLE LIPS OF A MOUTH OF A BAG OR LIKE CONTAINER

(WO2005056422) 23.06.2005 B65D 33/16 GREENPAC (UK) LIMITED
A closure (1) comprises a foldable member having a pair of flaps (5, 6). The flaps (5, 6) define at least one channel (7) for receiving flexible lips (4) of a mouth (3) of a bag (2) or like container. An adjunct strip (8) is foldably connected to a first such flap (5) so that the other flap (6) can be folded inside the adjunct strip (8) with the other flap (6) and the folded lips (4) of the bag (2) being trapped between the first flap (5) and the adjunct strip (8). The first flap (5) and the adjunct strip (8) are provided with co-operating integral formations for securing the closure (1) in closed condition.
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CAPSULE-CONTAINING ORAL COMPOSITION

(WO2005055967) 23.06.2005 A61K 8/11 SUNSTAR INC.
A capsule-containing oral composition that at the use thereof, realizes easy disintegration of capsule grains contained therein to thereby induce speedy release and dispersion of the capsule contents and that at the time of wash out, causes substantially no feeling of capsule component residue or feeling of foreign matter in the mouth. In particular, there is provided a capsule-containing oral composition characterized in that the capsules of the composition exhibit a disintegration strength, as measured by means of a rheometer, of 0.05 N or less.
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COMPOSITION AND METHOD FOR PREVENTION AND TREATMENT OF DENTAL CARIES

(WO2005053630) 16.06.2005 A61K 7/20 YAMAGISHI, Kazue
The present invention relates to compositions and methods for prevention and treatment of dental caries (44). A dental paste (38) is produced from a silicate containing hydroxyapatite (SiHAp) powder, an aqueous solution of hydrogen peroxide and an aqueous solution of phosphoric acid. The dental paste (38) containing SiHAp is applied to an enamel (16) of a tooth (15), dissolves a portion of the enamel (16) and integrates with the enamel (16) of the tooth (15) to produce a synthetic enamel (46). The dental paste (38) containing SiHAp crystallizes by integrating with a chemically incomplete portion of the tooth (15). The synthetic enamel (46) comprises a chemical composition and a crystal structure approximately the same as the hydroxyapatite ...
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USE OF OSTEOPONTIN IN DENTAL FORMULATIONS

(WO2005053628) 16.06.2005 A61K 8/64 ARLA FOODS AMBA
Use of osteopontin for reducing plaque bacterial growth on tooth enamel and dental formulations containing osteopontin.
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METHOD OF FORMING A DENTAL PRODUCT

(WO2005053621) 16.06.2005 A61C 13/00 DENTSPLY INTERNATIONAL INC.
The invention provides a method of shaping a dental product, comprising: shaping a curable polymerizable composition to form a shape of a dental product. The polymerizable composition is adapted to cure to form polymeric material, which at 37C has a flexural modulus of less than 250,000 psi and a flexural strength of less than 7,000 psi.
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ASSISTANT FOR IMPLANT STENT AND USING METHOD THEREOF

(WO2005053566) 16.06.2005 A61C 1/08 KIM, Jong-Pil
The present invention relates to an assistant for implant stent and using method thereof, and provide the assistant for implant stent comprises, a plate-shaped supporting part; and a guiding part which is extended from the center portion of said supporting part, and in which a drill connecting hole is formed to communicate, wherein the assistant is inserted from the upper part of the implant stent. And, the present invention also provides a method for using the assistant for implant stent comprising the steps of: making plaster cast of mouth, and mounting; making a stent based on the manufactured plaster cast; boring a hole on the center of the stent; incising gingiva of a patient; setting the manufactured stent; checking the location of ho...
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METHOD FOR FORMATION OF ENHANCED EXPANDABLE FOOD

(WO2005051097) 09.06.2005 A23L 1/164 KELLOGG COMPANY
A method of forming an expandable food product having enhanced expandability is disclosed. In the method a cooked starchy farinaceous composition is treated by flash frying in a heated media for a period of from 1 to 15 seconds. The flash fry treatment leads to enhanced expandability, an enhanced percentage of expanded pieces, enhanced coating retention, and an enhanced high fat mouth feel to the food product. The flash fry media can be an edible oil, a paraffin, or a caustic bath of baking soda in water. The product produced has unique consumer appeal.
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METHOD AND COMPOSITION FOR BREATH FRESHENING

(WO2005048965) 02.06.2005 A23L 1/00 WM. WRIGLEY JR. COMPANY
An oral composition for freshening the breath of consumers of tobacco products includes an oral cavity delivery agent, which can be a non-oxidizing oral cavity delivery agent, and an effective amount of a polyphenolic apple extract. The polyphenolic compounds in the apple extract react with nitrogen compounds in the consumers breath to reduce the concentration of the nitrogen compounds in the smoker's mouth. The oral products of this invention include chewing gums, edible thin film compositions, confectionary compositions, mouth sprays, and dentifrices. A method includes applying a non-oxidizing oral cavity delivery agent and a polyphenolic apple extract to the oral cavity of consumers of tobacco products.
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METHOD AND SYSTEM FOR PERIODONTAL CHARTING

(WO2005048869) 02.06.2005 A61C 19/00 WARNER-LAMBERT COMPANY LLC
Methods and systems for graphically depicting gum tissue and teeth for illustrating gingival health and plaque reduction. The relative risk as one type of statistical methods for comparing two treatments of different therapeutic agents for gingivitis and plaque are displayed. The upper and lower sets of teeth are represented in rows or groups of teeth separated by rows of boxes which depict the result of various treatments by various therapeutic agents.
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MODULATING SUBSTANCES OF THE NITRIC OXID (NO) - CYCLIC GUANOSINE - 3,5- MONOPHOSPHATE (cGMP) SIGNALING PATHWAY FOR THE TREATMENT OF DENTAL DISORDERS

(WO2005046660) 26.05.2005 A61K 31/00 CELL CENTER COLOGNE GMBH
The use of a modulating substance of the nitric oxide (NO) - cyclic guanosine-3',5'-monophosphate (cGMP) signaling pathway for the preparation of a pharmaceutical composition for the prevention and/or treatment of a dental disorder in a mammal is disclosed. Furthermore, pharmaceutical compositions comprising a modulating substance of the NO-cGMP signaling pathway as well as methods for treating a dental disorder are provided.
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CLEANING BRUSH WITH DISPOSABLE/REPLACEABLE BRUSH HEAD

(WO2005046418) 26.05.2005 A47K 11/10 S. C. JOHNSON &SON, INC.
Disclosed are brushes for cleaning toilet bowls and the like. The brushes have a permanent handle and can be used with a replaceable/disposable brush head that is flushable after use. The brush is a stack of sheets of water-dissolvable material. The sheets are compressed to both bind them together into a stack and create axial/longitudinal undulations. A wand provides a remote system for clamping and unclamping the brush head. The wand has a jaw whose mouth has corresponding undulating configurations. A side opening in the jaw may also be provided to facilitate assembly, as may a rear catch portion on the brush head.
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CLEANING BRUSH WITH REPLACEABLE/DISPOSABLE BRUSH HEAD

(WO2005046417) 26.05.2005 A46B 7/04 S. C. JOHNSON &SON, INC.
Disclosed is a brush for cleaning toilet bowls and the like. The brush has a permanent handle and can be used with a replaceable/disposable brush head that: is flushable after use. The brush is a stack of sheets of water-dissolvable material. The sheets are compressed to both bind them together into a stack. There is a longitudinal slit in the rear of the brush head to create left and right rear attachment tabs. A wand provides a remote system for clamping and unclamping the brush head. The wand has a jaw whose mouth has two wedge shaped teeth that are offset from each other to clamp the corresponding tabs while driving the tabs in opposite directions in the jaw.
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POWDER INHALER

(WO2005044353) 19.05.2005 A61M 15/00 BOEHRINGER INGELHEIM INTERNATIONAL GMBH
The invention relates to an inhaler for the inhalation of powdery medicaments in a capsule form. Said capsules are inserted, prior to use, into a capsule holder (3) arranged inside the inhaler (3). After the capsule is inserted into the capsule holder, the patient can press the actuating element (8) which can be displaced from a resting position and which co-operates with at least one needle (9) pushed into the capsule holder. The aim of the invention is to further improve said type of inhalers with respect to operational comfort. Said aim is achieved by providing an embodiment of an inhaler wherein the actuating element is embodied as a multifunctional actuating element (8a), thereby enabling the cover (5) of the lower part (1) to pivot wh...
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RECALCIFICATION PROMOTER, ORAL COMPOSITION, FOOD AND DRINK

(WO2005044210) 19.05.2005 A61K 8/19 KABUSHIKI KAISHA SANGI
[PROBLEMS] To provide an oral composition that can effectively promote the recalcification of tooth enamel decalcified at its surface and can positively suppress dental caries. [MEANS FOR SOLVING PROBLEMS] There is provided a recalcification promoter for tooth enamel comprising conchiolin and/or hydrolyzed conchiolin as an effective ingredient to which a calcium compound, especially preferably hydroxyapatite, is added.
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TOOTHBRUSH EMPLOYING AN ACOUSTIC WAVEGUIDE

(WO2005044129) 19.05.2005 A46B 9/04 UNIVERSITY OF WASHINGTON
A power toothbrush (10) is disclosed having a handle (15) containing a rechargeable battery (12), an ultrasonic drive circuit (14), a sonic component (16) such as a motor, and a control unit (18). The handle is connected to a toothbrush head (20) preferably having a plurality of bristles (26) and an ultrasonic transducer (22) that is operatively connected to a waveguide (24) that extends from the toothbrush head generally adjacent the bristles. The waveguide facilitates the transmission of acoustic energy into the dental fluid. It is contemplated that the waveguide may be utilized in manual or power toothbrushes, and in a combination without the sonic component, or in a combination without the ultrasonic transducer. Toothbrushes disclosed h...
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MILKING EQUIPMENT AND METHOD

(WO2005043986) 19.05.2005 A01J 5/08 DUKE, James, Richard, John
In apparatus and methods for applying treatment and cleaning fluid to cows teats and the teat cups of milking equipment, post-milking, each teat cup (1) has a nozzle (13) in the head portion (6) of the flexible liner (3) of the teat cup for delivering fluid internally of the teat cup. The nozzle is directed so as to discharge fluid towards the discharge end (4) of the teat cup. When milking is terminated, treatment fluid is injected through the nozzle (13) into the head portion of the liner (3) just prior to and/or as the teat cup is being withdrawn from the teat and, as a result, the teat cup wipes the injected fluid down the teat so as substantially to coat the teat with the treatment fluid. When the teat cup (1) falls into an inverted re...
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TOOTHPASTE CAP

(WO2005042367) 12.05.2005 B65D 35/44 KIM, Song Hun
The present invention provides a toothpaste cap easily separated and combined with only one hand, thereby maximizing convenience of use and thereby reducing concerns of loosing and contaminating the toothpaste cap. The toothpaste cap comprises a cap portion 1 combined with a discharge portion 9a of a toothpaste tube 9; a sucking means 2 attached on the wall; and a hinge lever 4 of which a part is provided to be available for an angular motion through a shaft hole 3 formed on the sucking means 2 and both end portions are combined through shaft holes 5 of the cap portion 1.
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PORTABLE DENTAL CARE STAND

(WO2005041809) 12.05.2005 A61B 17/00 JANG, Hyun Yang
The present invention provides a portable dental care stand. The portable dental care stand includes: a cover part having a handle formed at an upper portion; a machine part connected with the cover part by using a separable hinge, and the machine part having: an upper plate covering an upper portion of a rectangular housing, which is opened at the upper portion and a lower portion, a rectangular machine chamber having an opened upper portion and disposed at a predetermined removed portion of the upper plate, an operation panel having a predetermined slanting surface and installed at the opened upper portion of the machine chamber, the operation panel having a plurality of operation buttons at the slanting surface, and a mount installed usi...
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NOVEL PHOTOPOLYMERS AND USE IN DENTAL RESTORATIVE MATERIALS

(WO2005041807) 12.05.2005 A61C 13/08 THE REGENTS OF THE UNIVERSITY OF COLORADO
Photopolymerizable polymer composites based on dimethacrylate systems have been increasingly utilized as dental restorative materials. One of the biggest drawbacks of current dental resin systems is the volume shrinkage and shrinkage induced stresses that arise during the polymerization. Other major problems include incomplete double bond conversion and insufficient wear resistance. This invention involves the development of an entirely novel approach to the photopolymerization process that utilizes thiol-ene systems as low shrinkage and ultra-low shrinkage stress dental restorative materials. Compared with the traditional dimethacrylate dental resins, these novel photopolymerizations have demonstrated a dramatically decreased volume shrink...
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COATED PET FOOD COMPOSITION

(WO2005041682) 12.05.2005 A23K 1/165 HILL'S PET NUTRITION, INC.
A composition comprising a physically discrete pet food oral intake composition coated with a physically stable film, the film comprising a component which is a) capable of carrying a beneficial agent to a site in the pet wherein the benefit agent is effective in producing a beneficial effect or b) capable of releasing the benefit agent into the mouth or alimentary canal with the benefit agent traveling to a site in the pet wherein the benefit agent is effective in producing a beneficial effect.
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ORAL COMPOSITIONS COMPRISING ERYTHRITOL FOR THE TREATMENT OF DENTAL-PLAQUE AND ORAL INFECTIONS

(WO2005039518) 06.05.2005 A61K 8/34 CERESTAR HOLDING B.V.
The current invention relates to the use of erythritol to prevent, suppress and/or reduce dental plaque formation and/or infections in the mouth, in saliva, and/or in the throat.
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MOTORIZED FLOSSER AND ASSOCIATED METHOD OF USE

(WO2005039431) 06.05.2005 A61C 15/00 THE WILLIAM GETGEY COMPANY, INC.
A motorized flosser (10) comprising an elongated body (12) and a replaceable flossing head (18) secured to an end portion (14) of the elongated body (12) is provided. The flossing head (18) oscillates in a rotary or arcuate manner a length of flossing material (134) across the surface of a users teeth. A battery powered motor (48) drives a drive mechanism (50) which reciprocates in an oscillatory manner. The drive mechanism (50) is coupled to a disk (100) which oscillates in a arcuate or rotary motion. The disk (100) oscillates in an arc of approximately sixty degrees. A removable and replaceable flossing head (18) having a length of floss (134) extending between two tines (128a, 128b) is removably coupled to the disk (100). Preferab...
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DISPOSABLE TOOTHBRUSH WITH INTERNAL DENTAL PASTE

(WO2005039352) 06.05.2005 A46B 11/00 ROCHA, Mariangela Zardine
The present invention patent includes a toothbrush with a Rigid Handle (5), which contains an Internal Bag (1). This Internal Bag (1) is connected to a Duct (3) through which the toothpaste is fed for storage in the Internal Bag (1). The Duct (3) is sealed after the introduction of the toothpaste to prevent leakage. The Disposable Toothbrush also has an Exit Duct (4) which connects the Internal Bag (1) to the Flexible Bristles (2) in such a way as to allow the transferring of the stored toothpaste and it's spreading in between the Bendable Bristles (2) as soon as the Bendable Cover (6) is pressed.
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COMPOSITION FOR TABLET RAPIDLY DISINTEGRABLE IN MOUTH

(WO2005037319) 28.04.2005 A61K 9/00 FUJI CHEMICAL INDUSTRY CO., LTD.
A tablet rapidly disintegrable in the mouth. It disintegrates in a shorter time than rapidly disintegrable tablets obtained by conventional techniques and has a sufficient hardness. The tablet rapidly disintegrable in the mouth is obtained from a composition comprising (a) 40 to 90 parts by weight of saccharide derivatives comprising a combination of mannitol and xylitol; (b) 1 to 30 parts by weight of an inorganic excipient; and (c) 5 to 40 parts by weight of a disintegrator, the sum of the ingredients (a), (b), and (c) being 100 parts by weight.
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TOOTH ENAMEL REJUVENATING TOOTHPASTE

(WO2005037241) 28.04.2005 A61K 7/16 CHURCH &DWIGHT CO., INC.
An oral composition is provided which is effective for mineralization of surface enamel comprising a first part containing a partially water soluble calcium salt and a second part containing a fluoride salt and a bicarbonate salt. The oral composition can be a toothpaste and wherein the second part preferably contains sufficient bicarbonate salt to provide a fresh, clean feeling to the oral cavity.
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PREVENTION OF CRYSTAL FORMATION IN TOOTHPASTE

(WO2005037240) 28.04.2005 A61K 7/16 CHURCH &DWIGHT CO., INC.
In dentifrices containing sodium bicarbonate and anionic species which can react with sodium and water to precipitate hydrated crystals, the ratio of water to humectants, abrasives, and/or thickeners is adjusted so that the dentifrice has a water activity of no greater than 0.60 so as to greatly reduce the salting out of the anionic species.
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BEVERAGE CONTAINER AND TOOTHBRUSH HOLDER

(WO2005037040) 28.04.2005 A45D 44/18 ANDRION, Gil, N.
A beverage container (10) having a recessed storage compartment (20) for storing a toothbrush (16) and a tube of toothpaste (18). The toothbrush (16) and the tube of toothpaste (18) are stored in a cylindrical case (20) that fits into the recessed storage compartiment (20) of the container (10). The case (20) has a cap (22) and the container (10) has a cap (14).
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CONDUCTIVE POLYMER

(WO2005035655) 21.04.2005 C08L 65/00 HERIOT-WATT UNIVERSITY
This invention relates to an intrinsically conducting polymer (ICP), a plastics based electrode and a method for making such an electrode. In particular, the plastics based electrode comprises a plastic strip of cellulose acetate acting as a substrate with a thin coating of intrinsically conducting poly (3,4-ethylenedioxythiophene) and poly (4-styrenesulphonate) (i.e. PEDOT/PSS) polymer comprising an amount of vinylacetate/ethylene copolymer. The plastics based electrode may be used in apparatus for the detection of dental caries.
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PROTEIN BIOMATERIALS AND BIOCOACERVATES AND METHODS OF MAKING AND USING THEREOF

(WO2005034852) 21.04.2005 A61K 31/715 GEL-DEL TECHNOLOGIES, INC.
The present invention relates to protein biocoacervates and biomaterials and the methods of making and using protein biocoacervates and biomaterials. More specifically the present invention relates to protein biocoacervates and biomaterials that may be utilized for various medical applications including, but not limited to, drug delivery devices for the controlled release of pharmacologically active agents, coated medical devices (e.g. stents, valves ... ), vessels, tubular grafts, vascular grafts, wound healing devices including protein suture biomaterials and biomeshes, dental plugs and implants, skin/bone/tissue grafts, tissue fillers, protein biomaterial adhesion prevention barriers, cell scaffolding and other biocompatible biocoacervat...
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METHODS FOR TREATING DENTAL CONDITIONS USING TISSUE SCAFFOLDS

(WO2005034789) 21.04.2005 A61C 5/04 DENTIGENIX INC.
The invention provides methods, apparatus and kits for regenerating dental tissue in vivo that are useful for treating a variety of dental conditions, exemplified by treatment of caries. The invention uses tissue scaffold wafers, preferably made of PGA, PLLA, PDLLA or PLGA dimensioned to fit into a hole of corresponding sized drilled into the tooth of subject to expose dental pulp in vivo. In certain embodiments the tissue scaffold wafer further comprises calcium phosphate and fuloride. The tissue scaffold wafer may be secured into the hole with a hydrogel, a cement or other suitable material. Either the wafer or the hydrogel or both contain a morphogenic agent, such as a member encoded by the TGF- surpergene family, that promotes rege...
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TOOTH CONTAINING IMAGE THEREON

(WO2005034788) 21.04.2005 A61C 13/083 KIM, Yong, Woon
A dental construct is provided, which includes: a dental construct substrate; an image layer disposed at least partially on a surface of the dental construct substrate, the image layer comprising an image or information media composed of a colorant composition, the image layer fused at a temperature and being essentially free of lead and cadmium; and, a ceramic layer disposed at least partially over a surface of the dental construct substrate and covering at least the surface of the image layer, the ceramic layer comprising at least one or both of a ceramic material and a glaze material, the ceramic layer fused at a temperature, the ceramic layer being generally transparent and essentially free of lead and cadmium. The dental construct subs...
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DENTAL APPARATUS WITH OZONE IRRIGATION SYSTEM

(WO2005032393) 14.04.2005 A61C 5/02 PRODEX
A dental apparatus is provided with an ozone irrigation system. Ozonated water is produced in the irrigation system and supplied to the dental apparatus. The dental apparatus can have a handpiece that drives a cannulated instrument, such as a cannulated file. The ozonated water can be supplied to an axial passage formed in the instrument. Radial ports are provided through the instrument such that the ozonated water can spray radially outward into a treatment zone during movement of the instrument. The ozonated water thereby can lubricate and cool the treatment zone while also providing advantageous cleaning of the zone.
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APPLICATOR FOR CLEANING TEETH

(WO2005030314) 07.04.2005 A46B 11/00 WARNER-LAMBERT COMPANY LLC
A disposable teeth cleaning applicator device. An elongated tubular shaft member has an applicator tip member at one end and a toothpick device at the other end. A liquid dental material is positioned inside the tubular shaft member and, once released, is squeezed or allowed to flow into the applicator tip member which possesses at least one abrasive surface and used to clean a person's teeth.
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PACKAGED DENTAL COMPOSITION

(WO2005030080) 07.04.2005 A61C 5/06 DENTSPLY INTERNATIONAL INC.
The invention provides a container enclosing an applicator and a dental composition including a volatile organic solvent. The container is sealed. The volatile organic solvent is effectivelyretained within the container, even after storage at about 43C for one week. Preferably the container is made of a copolymer of a cycloolefin and an open chain olefin.
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DISPENSING BRUSH

(WO2005030004) 07.04.2005 A46B 11/02 GLOVER, Scott, J.
A combination brush and cleaning agent is disclosed such as a combination toothbrush, toothpaste and floss dispenser having a soft bristle brush head, a usage paste reservoir and dental floss, The product is designed to use a replacement cartridge. The unit comes with a clear head cover that is vented to allow the brush to dry after use. An upper assembly includes a clear head cover, brush head/neck, plunger button, suction plunger, spring, feed tube straw, ball check connect and adapter, which can be threaded or a snap-lock. A lower assembly includes of an O-ring, clear paste reservoir handle, piston, stainless steel metal cleat, bottom cover and base cap with floss spool post and cutter. Depressing the plunger button depresses the suction...
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PILL DISPENSERS

(WO2005028316) 31.03.2005 B65D 83/04 COPE ALLMAN PLASTIC PACKAGING LIMITED
A hollow pill dispenser (1) has a mouth (9) at one end to slidingly receive a blister strip (7) so that the blister strip (7) is substantially contained within the dispenser (1). The dispenser (1) is provided with engagement means (17, 29) which directly engages a formation (23) provided on the blister strip (7) to retain the blister strip (7) within the dispenser (1). The dispenser (1) further comprises release means (15, 16, 29) operative to release the engagement between the formation (23) and the engagement means (17, 29) so that the blister strip (7) can be pulled from the dispenser (1) through the mouth (9) of the dispenser (1) to expose a predetermined number of pills, the engagement means (17, 29), when the predetermined number of p...
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NUTRITIONAL SUPPLEMENT AND PROTOCOL

(WO2005027897) 31.03.2005 A61K 31/195 MED FIVE, INC.
Particular nutritional supplements and protocols emphasize the use of ethylenediamine tetraacetic acid as a mouth rinse, and as an enteric-coated oral pharmaceutical, further supplemented on a daily basis with both a combination of phosphatidyl lipids and alpha lipoic acid and a nutritional supplement containing approximately equal amounts of Reishi and Shiitake mushrooms.
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ORAL AND DENTAL HYGIENE PRODUCT

(WO2005027863) 31.03.2005 A61K 8/02 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to oral and dental hygiene products comprising a) a composite material containing poorly water-soluble calcium salts in the form of nanoparticulate primary particles which are between 5 and 150 nm long and have a cross-section of between 2 and 50 nm, and protein constituents selected from proteins, protein hydrolysates and protein hydrolysate derivatives, and b) between 0.1 and 9 wt. % of a cleaning agent, in relation to the total weight of the product. The inventive oral and dental hygiene product ensures an effective and long-lasting remineralisation of the surface of the tooth, and a protective cleaning action of the cleaning or polishing agent.
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ORAL COMPOSITION COMPRISING A COPOLYMER COMPRISING CATIONIC AND ANIONIC OR NEUTRAL COMONOMERS

(WO2005027862) 31.03.2005 A61K 7/16 UNILEVER N.V.
Oral care composition comprising a polymer obtainable by copolymerising a mixture of comonomers, said mixture comprising: (a) a cationic monomer selected from (ar-vinylbenzyl) trimethylammonium chloride, (dimethylaminopropyl) methacrylamide, [2(methacryloyloxy)ethyl]trimethylammonium chloride, 2-aminoethylmethacrylate hydrochloride and mixtures thereof; and (b) at least one anionic or neutral monomer selected from styrene, mono-2-(methacryloyl)ethyl succinate, vinyl acetate, N,N-dimethylacrylamide, 2-ethylhexylacrylate, vinylphosphonic acid, acrylic acid, 2-acrylamido-2-methyl-1-propanesulfonic acid, N-[tris(hydroxymethyl)methyl] acrylamide, N-vinylpyrrolidone, butyl acrylate, 2-hydroxyethylacrylate, polyethyleneglycol methylethermethacryla...
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POLYMERIZABLE DENTAL COMPOSITION HAVING A HIGH CONTENT OF LOADING MATERIAL

(WO2005027857) 31.03.2005 A61K 6/093 RHODIA CHIMIE
The invention relates to cationic dental compositions that are stable and highly loaded. This dental composition comprises: (1) at least one functionalized silicone ethylene oxide that is reactive cationically and under UV; (2) at least one dental loading material (SiO2); (3) a dispersant based on a polyurethane/acrylate copolymer salified by an alkylammonium whose amine index is less than 100 mg of potash per gram of dispersant; (4) a cationic photoinitiator (iodonium borate), and; (5) a photosensitizer. These dental compositions can be used for producing dental prostheses and for dental restoration.
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METHOD OF APPLYING ORAL COMPOSITIONS

(WO2005027815) 31.03.2005 B65D 47/42 SMITHKLINE BEECHMAN CORPORATION
A method of applying oral compositions to the temporary and permanent surfaces of the oral cavity comprising the step of obtaining a container and applicator combination formed as an assembly that comprises an internal region that contains an oral care composition and an externally projecting pair of speadable wings, expelling said oral care composition from said internal region and spreading said oral care composition onto the surfaces of the oral cavity with said spreadable wings.
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METHOD OF PROMOTING SUBSISTENCE AND/OR PROLIFERATION OF NEURAL STEM CELL AND PROMOTING EXTENSION OF NEURITE, PROMOTER THEREFOR, PHARMACEUTICAL COMPOSITION CONTAINING NEURAL STEM CELL, METHOD OF ASSAY AND METHOD OF SCREENING

(WO2005026343) 24.03.2005 C12N 5/06 KEIO UNIVERSITY
[PROBLEMS] To provide a method of promoting the subsistence and/or proliferation of neural stem cells; a pharmaceutical composition containing neural stem cells produced by the method; and a method of assaying and method of screening a factor capable of promoting the subsistence and/or proliferation of neural stem cells. [MEANS FOR SOLVING PROBLEMS] Excess expression of galectin-1 is effected in neural stem cells, or neural stem cells are cultured in a culture solution containing galectin-1. The pharmaceutical composition comprising the thus produced neural stem cells wherein excess expression of galectin-1 is effected and the pharmaceutical composition comprising galectin-1 ameliorate high-order functions having been disordered by intracer...
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PUMPING AND FLOATING PISTONS COATED WITH A BARRIER LAYER

(WO2005023655) 17.03.2005 B65D 83/00 GLAXOSMITHKLINE CONSUMER HEALTHCARE GMBH &CO KG
Pumping and floating pistons (70) suitable for a hand pump (10) for a viscous fluid material such as a toothpaste, made of a plastics material coated with a barrier layer (75). A preferred barrier layer is a thermoplastic elastomer. The barrier layer of the pumping piston may be integrally formed into a one way outlet valve. The barrier layer reduces leakage of components of the fluid material out through the piston, or ingress of environmental components through the piston.
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TREATMENT COMPOSITIONS AND DEVICES HAVING A SOLID ADHESIVE LAYER AND A TREATMENT GEL

(WO2005023142) 17.03.2005 A61C 5/00 ULTRADENT PRODUCTS, INC.
Treatment compositions in the shape of a dental tray (10), strip or patch include an adhesive composition (20) and a treatment gel (28). A barrier layer (18) may be included to form a treatment device (10) that protects the treatment gel (28) from saliva or moisture during use. The adhesive composition (20) is substantially solid and has increased adhesiveness to oral tissue when moistened with saliva or water. The adhesive composition (20) is formed from an intermediate composition that is heated to drive off the solvent. Using a treatment gel (28) separate from the adhesive composition (20) improves the potency and stability of the active agent prior to use.
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STENT FOR GUIDING THE LOCATION/DIRECTION OF IMPLANT, AND PRODUCTION METHOD THEREOF

(WO2005023138) 17.03.2005 A61C 1/08 MJRAD CO., LTD.
The present invention is disclosed a stent for guiding the location/direction for the insertion of an implant and a production method thereof. The method includes the steps of forming a plaster cast modeling of a mouth state using a plastic replica; and manufacturing a plastic cast model having an occlusal surface of the location for the insertion of the implant using the plaster cast; fastening a plastic plate having on corners thereof a plurality of metal balls to an upper end of the plastic cast model; and obtaining computed tomographic (CT) image of the mouth after placing the plastic cast model, on which the plastic plate is fastened, in the mouth, and forming a hole in a predetermined position in the stent to correspond to both a loca...
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TEETH WHITENING COMPOSITION AND METHOD

(WO2005023130) 17.03.2005 A61C 19/06 MILESTONE SCIENTIFIC, INC.
A dental whitening composition is formed from tablet formulation containing a metal ion catalyst and an alkaline pH raising compound and a peroxide solution having a concentration of about 1 percent to about 15 percent peroxide. The combination of the tablet formulation containing the metal ion within an alkaline composition along with the peroxide rinse forms a dental composition having foam like consistency, which whitens the surface of teeth. The tablet formulation can also be in the form of a gel or solution. The process of whitening teeth is accelerated by using a light emitting device producing a selected wavelength range. The light emitting device can be incorporated into a dental tray having a dental receiving area formed from a pol...
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ANTIMICROBIAL COMPOSITIONS AND METHODS

(WO2005022998) 17.03.2005 A01N 31/06 3M INNOVATIVE PROPERTIES COMPANY
The present invention is generally related to a product and process to reduce the microbial contamination on organic matter, such as processed meat, fruits and vegetables, plant parts, inanimate surfaces such as textiles and stainless steel, and in the mouth or on dental products. In particular, the invention is related to a product and process to disinfect surfaces using an antimicrobial composition containing an antimicrobial lipid, an enhancer selected from the group consisting of bacteriocins, antimicrobial enzymes, sugars, sugar alcohols, iron-binding proteins and derivatives thereof, siderophores, and combinations thereof, and optionally a surfactant.
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UNDERWATER CLEANER

(WO2005021896) 10.03.2005 E04H 4/16 BATTERY POOL CLEANER GMBH
The invention relates to an underwater cleaner (1), particularly for a swimming pool, comprising a suction nozzle housing (3) that has a suction nozzle (2), which communicates with a suction chamber (4), and has a suction mouth (19), which defines a suction plane (16), whereby a discharge channel (5) emanates from the suction chamber (4), and a filter device (6) is connected to said outlet channel. The inventive device also comprises a water jet nozzle (7) that leads into the suction chamber (4) and via which water under pressure can be fed into the suction chamber (4) whereby, according to the principle of the water jet pump, giving rise to a vacuum inside the suction chamber (4). The aim of the invention is, in the simplest possible manne...
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ORAL AND DENTAL CARE PRODUCT

(WO2005020878) 10.03.2005 A61K 8/19 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to oral and dental care products, comprising a) a composite material containing poorly water-soluble calcium salts in the form of nanoparticulate primary particles with a length of 5 to 150 nm and a cross-section of 2 to 50 nm, protein components selected from proteins, hydrolysed protein and hydrolysed protein derivatives and b) 10 to 35 % of a mixture of cleaning agents, whereby said cleaning agent mixture contains 0.01 to 5 wt. % of aluminium oxide polishing agent. Said oral and dental care products guarantee a thorough cleaning of the teeth with simultaneous and persistent remineralisation of the tooth surfaces.
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CASE FOR RETAINING DENTAL CLEANING TOOLS

(WO2005020837) 10.03.2005 A61B 17/24 GWEN, Patrick
A dental tool apparatus (10) has a case (12) and a first cleaning tool (14) pivotally mounted in the case (12) so as to be movable between a first position within the case to a second position extending outwardly of the case. The first cleaning tool (14) is a toothbrush that has bristles (20) extending outwardly therefrom transverse to the longitudinal axis of the case (12) when the toothbrush (18) is in the first position. A second cleaning tool (34) and a third cleaning tool (36) are also pivotally mounted within the case (12). A closure member (26) is pivotally connected to the case (12) so as to be movable between a covering position and an open position.
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DENTAL BLEACHING

(WO2005018592) 03.03.2005 A61K 8/22 PERSONAL PRODUCTS COMPANY DIVISION, MCNEIL-PPC, INC.
The present application concerns a composition for whitening one or more teeth comprising a whitening agent and petrolatum, espacially white petrolatum. In one embodiment of the invention, the composition comprises a peroxide, a solvent, a polyoxyalkylene, a petrolatum and a polyvinyl pyrrolidone.
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SELF-ETCHING DENTAL COMPOSITIONS AND METHODS

(WO2005018581) 03.03.2005 A61K 6/00 3M INNOVATIVE PROPERTIES COMPANY
The present invention is directed to dental compositions that can be used as adhesives for bonding a dental material to a dental structure surface and/or as a dental restorative material. The dental composition is preferably applied to a dental structure surface under conditions effective to etch the dental structure surface.
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ORTHODONTIC BRACE

(WO2005018480) 03.03.2005 A61C 7/10 BARNET &CHASE FARM HOSPITALS NHS TRUST
The invention provides a corrective orthodontic brace wherein a spring means acts upon one or more molars to move them towards the back of a user's mouth. The forces are transmitted to a support plate shaped to fit closely on the keratinised tissue of a user's mouth.
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USE OF PHOSPHOPHORYN FOR INDUCING BIOMINERALIZATION AND BONE REGENERATION

(WO2005016368) 24.02.2005 A61K 38/18 UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
A method of inducing biomineralization in a tissue, which method comprises administering to the tissue a source of Phosphophoryn (PP) in an amount sufficient to induce biomineralization; a method of treating tooth sensitivity or injured pulp tissue; a method of inducing differentiation of a cell into an osteogenic cell or odontogenic cell; a method of inducing bone or dentin regeneration; a method of inducing periodontal regeneration; a method of inducing differentiation of a cell into a cementoblast, osteoblast, or periodontal ligament cell; and a composition comprising a source of PP and a carrier.
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HYDROPHOBIC TOOTH WHITENING SYSTEM AND METHODS OF USE

(WO2005016299) 24.02.2005 A61C 19/06 COLGATE-PALMOLIVE COMPANY
A tooth whitening system comprising a dental tray having a surface operable to confront a tooth surface, and a tooth whitening composition comprising a whitening agent and a hydrophobic polymer carrier. The tooth whitening composition is preferably substantially non-water soluble. A tooth whitening kit is also provided using a dental tray and the tooth whitening composition comprising a whitening composition and a hydrophobic polymer carrier.
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POLYORGANOSILOXANE DENTAL IMPRESSION MATERIALS

(WO2005016289) 24.02.2005 A61K 6/10 DENTSPLY INTERNATIONAL INC.
A dental impression material comprising a polyvinylsiloxane and a surfactant, wherein said surfactant imparts wettability to the composition, such that the material has a surface contact angle with water of less than about 50 degrees after about 3 minutes.
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COMPOSITONS AND DEVICES HAVING A TRAY-LIKE CONFIGURATION

(WO2005016167) 24.02.2005 A61C 5/00 ULTRADENT PRODUCTS, INC.
Medicament compositions (10) are in the shape of a dental tray or tray-like configuration (12, 14, 16), optionally in combination with a protective barrier layer (18) to form a treatment device. Shaped medicament compositions (10) comprise a substantially solid medicament composition that has increased adhesiveness to teeth and/or gingiva when moistened with saliva or water. The shape of the medicament composition and/or treatment device facilitates placement of the composition of device over a person's teeth and/or gingiva with substantially less manipulation compared to the use of initially flat strips. The substantially solid medicament composition (10) becomes more adhesive when moistened with saliva or water, yet remains intact and coh...
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COMPOSITIONS INCORPORATING HIGH-CAFFEINE GREEN TEA EXTRACT AND RELATED METHODS FOR PROMOTING HEALTHY BODY WEIGHT

(WO2005014020) 17.02.2005 A61K 31/353 INTERHEALTH NUTRACEUTICALS INCORPORATED
Methods for promoting healthy body weight, increasing energy level and improving a variety of related physiological factors include administering to those persons or other mammals effective amounts of a composition incorporating EGCG and caffeine derived from green tea, preferably in equal or nearly equal amounts. The EGCG and caffeine in these amounts work synergistically to further promote body weight, increase energy level and improve these physiological factors.
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DENTAL COMPOSITION COMPRISING ETHYLENE IMINE COMPOUNDS AND NON-REACTIVE ACCELERATORS

(WO2005013924) 17.02.2005 A61K 6/10 3M ESPE AG
The present invention relates to a composition with enhanced speed of set, especially to a method of making rubber--like elastomers with improved hardening characteristics. In this respect the present invention provides a composition comprising with respect to the cured composition a ethylene imine group containing component A, a SO2-NH group containing component B and an initiator C. Optionally additives like modifiers, fillers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickeners, surfactants, odorous substances, diluters and flavourings can be added.
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METHOD AND PRODUCT FOR PHOSPHOSILICATE SLURRY FOR USE IN DENTISTRY AND RELATED BONE CEMENTS

(WO2005013923) 17.02.2005 A61K 6/00 DENTSPLY INTERNATIONAL INC.
The present invention is directed to magnesium phosphate ceramics and their methods of manufacture. The composition of the invention is produced by combining a mixture of a substantially dry powder component with a liquid component. The substantially dry powder component comprises a sparsely soluble oxide powder, an alkali metal phosphate powder, a sparsely soluble silicate powder, with the balance of the substantially dry powder component comprising at least one powder selected from the group consisting of bioactive powders, biocompatible powders, fluorescent powders, fluoride releasing powders, and radiopaque powders. The liquid component comprises a pH modifying agent, a monovalent alkali metal phosphate in aqueous solution, the balance ...
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DENTAL ROOT CANAL SEALING COMPOSITION

(WO2005013922) 17.02.2005 A61K 6/00 DENTSPLY DE TREY GMBH
A dental root canal sealing composition curable in the absence of a polymerisation initiator and having a viscosity at 23C of less than 100 Pas, which comprises (i) an amino terminated prepolymer obtainable by reacting (a) one mole of a compound of the following formula (I) wherein X represents a nitrogen or an oxygen atom; Z represents an n-valent saturated aliphatic or cycloaliphatic C2-16 hydrocarbon group which may contain 1 to 6 oxygen atoms, and which may be substituted by one or more C1-4 alkyl groups; and n represents an integer of from 2 to 6; and (b) at least n moles of one or more compounds either of the following formula (II) wherein R represents a C1-6 alkyl or a C3-,4 cycloalkyl group, which may be substituted by one or m...
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DENTAL ROOT CANAL SEALING COMPOSITION

(WO2005013921) 17.02.2005 A61K 6/00 DENTSPLY DETREY GMBH
A dental root canal sealing composition curable in the absence of a polymerisation initiator, which comprises: (i) an amino terminated prepolymer having a viscosity at 230C of less than 100 Pas, which is obtainable by reacting (a) one mole of a compound of the formula (I) wherein X represents a nitrogen or an oxygen atom; Z represents an n-valent saturated aliphatic C2-16 hydrocarbon group or a divalent saturated cycloaliphatic C3-6 hydrocarbon group, which groups may contain 1 to 6 oxygen atoms, and which may be substituted by 1 to 6 C1-4 alkyl groups; and n represents an integer of from 2 to 6; (b) at least n moles of one or more compounds either of the following formula (II) wherein A represents a divalent saturated aliphatic C2-16 hydro...
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CHEWING GUM AND CONFECTIONARY COMPOSITIONS CONTAINING A STAIN-REMOVING COMPLEX

(WO2005013712) 17.02.2005 A61K 9/68 CADBURY ADAMS USA LLC
A composition in the form of a chewing gum composition or a confectionery composition containing a stain removing complex of a stain removing agent and a cyclodextrin compound and methods of preparing and using the same to remove stains from dental material including teeth.
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OUTDOOR UNIT OF AIR CONDITIONER

(WO2005012801) 10.02.2005 F24F 1/00 DAIKIN INDUSTRIES, LTD.
An outdoor unit (3) of an air conditioner allowing an increase in air blowing performance, comprising an outdoor unit casing, a supply fan (38), a bell mouth (45), a fan motor (39), and a fan motor stand (44). The outdoor unit casing further comprises a top plate (50) disposed on the upper side thereof, a bottom plate (51) disposed on the lower side thereof, and a front plate (52) disposed on the front side thereof and having an air blow hole (59) formed therein. The supply fan (38) is stored in the outdoor unit casing, and generates air flow blown out through a blowout hole (59) in the front plate (52). The bell mouth (45) guides the air flow generated by the supply fan (38). The fan motor (39) rotatingly drives the supply fan (38). The fa...
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WEFT KNITTING MACHINE HAVING MOVABLE SINKER

(WO2005012613) 10.02.2005 D04B 15/06 SHIMA SEIKI MANUFACTURING LIMITED
A weft knitting machine having a movable sinker capable of securing a large space at a needle bed near a knitting fabric knitting area and making a pause in the state of stopping action on the knitting fabric knitting area. A sinker operating cam mechanism (10) installed in a carriage acts on the butt (12c) of a sinker jack (12) to move the sinker jack (12) backward from a mouth part (2) so that the acting part (8c) of the movable sinker (8) can retract from the mouth part (2). The sinker jack (12) is locked to a moved back position by a locking mechanism (16). Since a wire (17) passed through a needle plate (5) is utilized to lock the sinker jack (12) in the locking mechanism (16), the locking mechanism (16) can be reduced in size. To lock...
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SINKER DEVICE OF WEFT KNITTING MACHINE

(WO2005012612) 10.02.2005 D04B 15/06 SHIMA SEIKI MANUFACTURING LIMITED
A sinker device of a weft knitting machine, wherein a movable sinker (8) can move a tip part (8c) forward and backward relative to the mouth part thereof (2) by the swing displacement of a needle plate (5) about the recessed part (5a) thereof. A wire spring (10) energizes the movable sinker (8) so that the tip part (8c) can move forward to the mouth part (2). A stopper (20) allowing the contact portion (8e) of the tip part (8c) of the movable sinker (8) to abut thereon to restrict the swing displacement of the movable sinker (8) by the energization of the wire spring (10) is installed at the bottom part of a base (4) near the mouth part (2). The maximum pressed amount of the tip part (8c) of the movable sinker (8) is limited by the contact ...
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COMPOSITIONS, METHODS, DEVICES, AND KITS FOR MAINTAINING OR ENHANCING TOOTH WHITENING

(WO2005011582) 10.02.2005 A61C 15/00 BRITESMILE DEVELOPMENT, INC.
Compositions, methods, devices, and kits for maintaining or enhancing tooth whitening in a subject are disclosed. The methods include applying a first tooth whitening composition to the teeth of the subject for a predetermined period of time and applying a second tooth whitening composition to the teeth of the subject in predetermined intervals, wherein at least one of the first and second tooth whitening compositions are dispensed from a dental delivery device. The kits include a first tooth whitening composition and a second tooth whitening composition, each including an oxidizing agent. The oxidizing agent of the first tooth whitening composition is present in a higher amount than the second tooth whitening composition, which maintains o...
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DENTAL INSTRUMENT

(WO2005011518) 10.02.2005 A61C 3/00 COLGATE-PALMOLIVE COMPANY
This invention is directed to a dental instrument and the use of this dental instrument to measure deposits and other imperfections on a tooth surface. The dental instrument has an elongated portion and on at least one end a general curvature portion. The general curvature portion will have the general curvature of a posterior tooth or an anterior tooth. Preferably it also will be marked with measured segments. By placing the general curvature portion against a tooth a deposit or imperfection on a tooth can be measured. In a preferred embodiment the dental instrument will have a general curvature portion in each end; the general curvature on one end being for posterior teeth and the general curvature on the other end being for anterior teet...
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THE TRAVELLING DENTAL HYGIENE KIT KADET

(WO2005011436) 10.02.2005 A45D 44/18 STEMPLEWSKI, Kadet
The travelling kit is a combination of the tooth paste, toothbrush and the tooth mug; the set which is hygenic and convenient to use while travelling. It also enables to brush teeth not too long one toothbrush. The capacity of the toothpaste tube ranges from 125 to 150 millilitres.
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ULTRASONIC ASSISTED ETCH USING CORROSIVE LIQUIDS

(WO2005010950) 03.02.2005 B08B 3/04 CHEMTRACE PRECISION CLEANING, INC.
An ultrasonic etching apparatus for chemically-etching a workpiece is disclosed. The apparatus includes an outer tank at least partially filled with an aqueous solution, an inner tank at least partially disposed within the outer tank and in contact with aqueous solution, the inner tank at least partially filled with an etching solution, a lid engaged with the mouth of said inner tank; and an ultrasonic transducer coupled to the outer tank to impart ultrasonic energy to the etching solution in said inner tank. Also disclosed are methods of using the apparatus to etch workpieces.
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HEXAMERIC PORPHOBILINOGEN SYNTHASE AS A TARGET FOR THE DEVELOPMENT OF ANTIBIOTICS AND HERBICIDES

(WO2005007817) 27.01.2005 A61K 31/00 FOX CHASE CANCER CENTER
Compositions for inhibiting multimeric proteins porphobilinogen synthase and Class Ia ribonucleotide reductase, herbicide resistant plants adapted to be transgenic for multimeric porphobilinogen synthase and methods of use.
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PHOTOPOLYMERIZABLE COMPOSITION BASED ON AN EPOXYVINYLESTER RESIN AND A URETHANE ACRYLATE RESIN AND USE THEREOF FOR MAKING DENTAL PROSTHESIS PREFORMS AND/OR MODELS

(WO2005007743) 27.01.2005 C08L 75/16 COMMISSARIAT A L'ENERGIE ATOMIQUE
The invention concerns a photopolymerizable composition comprising: at least one epoxyvinylester resin, at least one urethane acrylate resin, at least one organic silicon-free particulate filler having an average particle size less than 10 $g(m)m and a specific surface more than 10 m2/g, at least one photoinitiator. Said composition is in particular useful for making dental prosthesis preforms and models.
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NICOTINE PACKAGING SYSTEM

(WO2005007068) 27.01.2005 A61K 9/00 THE KIWIGEL COMPANY LIMITED
The invention provides a packaging system (2) for a nicotine gel (12). It comprises a plastic sealing system (6, 8) adhered to a backing sheet (4), a nicotine gel concentrate (12) inside the sealing system and a position of weakness (14) in the packaging system such that the application of pressure to the position of weakness by the user results in the opening of the plastic sealing system hand the release into the users mouth of the nicotine containing gel. The system allows the user to mimic the and to mouth repetitive administration of a standard cigarette when delivering the gel to their mouth.
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ELECTRIC DEVICE FOR INTERDENTAL CLEANING AND FOR TREATING TEETH AND GINGIVAE

(WO2005007014) 27.01.2005 A61C 15/02 BRAUN GMBH
The invention relates to an electric device (1) for interdental cleaning and for treating teeth and gingivae comprising a casing (2) containing an eccentric mass (23) which is driven by an electric motor (22) and whose vibrations are transmitted to a tool holding fixture (5). A coupling area (A, B) for the tool holding fixture is connectable to a coupling area (34, 38) of a mouth cavity treating tool such as an interdental cleaner (31), a dental floss holder (37), friction and polishing discs, etc by means of connecting means. According to said invention, the tool holding fixture (5) consists of a pivot-shaped segment (48) and a coupling area (B) formed on the free front end face (61) of said segment, wherein said coupling area (B) is embod...
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ELECTRIC DEVICE FOR INTERDENTAL CLEANING AND FOR TREATING TEETH AND GINGIVAE

(WO2005007013) 27.01.2005 A61C 15/00 BRAUN GMBH
The invention relates to an electric device for interdental cleaning and for treating teeth and gingivae. Said electric device (1) comprises a casing (2) in which an eccentric mass (23) driven by an electric motor (22) is formed. The eccentric mass vibrations are transmitted to a tool holding fixture (5) in a coupling area (A, B) where mouth cavity cleaning tools such as an interdental cleaner (31), a dental floss holder (37), friction and polishing discs, etc are connected. According to said invention, the electric motor and the freely rotating eccentric mass thereof are fixed to the tool holding fixture (5), thereby making it possible to obtain an optimal vibratory behaviour of the electric device (1) provided with very small and energy s...
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CHEWABLE ANTIPLAQUE CONFECTIONERY DENTAL COMPOSITION

(WO2005006872) 27.01.2005 A23G 3/00 COLGATE-PALMOLIVE COMPANY
A chewable confectionery dental composition delivering to the mouth a unit dose of a plaque reducing enzyme the composition comprising an enzyme and a non-cariogenic sweetener, the enzyme being incorporated in the composition at a temperature less than about 80C.
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ADHESIVE COMPOSITION WITH DECREASED POLARITY UPON POLYMERIZATION

(WO2005004819) 20.01.2005 A61K 6/00 3M ESPE AG
The invention relates to adhesive compositions that exhibit a significant decrease in polarity upon polymerization. More specifically, it relates to curable self etching dental adhesive compositions that can be applied to the tooth hard substance in one step and exhibit this decrease in polarity upon curing. In this respect a formulation is provided combining phosphoric acid esters bearing substituents with one ethylenically unsaturated moiety on the phosphorus atom and phosphoric acid esters bearing substituents with two or more ethylenically unsaturated moieties on the phosphorus atom.
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CAP COMPRISING RECEPTACLE FOR DESICCANT

(WO2005002987) 13.01.2005 B65D 51/30 FABRI-PLAST, S.A.
The invention relates to a cap comprising a receptacle for a desiccant, which is intended for containers. The inventive cap essentially consists of (i) a main part (1) comprising a body (2) and a desiccant receptacle (3) which are produced from a single injection mould, and (ii) a seal (4) which is independent of the aforementioned body and receptacle and which comprises a mouth element (5). According to the invention, the mouth element (5) is press-inserted into the body (2) with the aid of a ring of bosses (6) which are distributed uniformly inside said body (2) and which, at the lower end thereof, define a strip (8) in which the mouth element (5) is housed.
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CHEWABLE DENTAL PRODUCT

(WO2005002464) 13.01.2005 A23G 4/00 YNDK PTY LTD
A dental cleaning composition which includes a chewable carrier material that is not a gum or foam and which is not readily soluble or dispersible in the mouth, a cleansing agent which is non foaming, a barrier material and/or anticariogenic or antibacterial agents. The tablet can be used with a chewable dental strip made from an open cell foam.
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MOUTH RINSE COMPOSITIONS CONTAINING N-ACYL-ARGININE ALKYL ESTER SALTS

(WO2005000261) 06.01.2005 A61K 8/42 COLGATE-PALMOLIVE COMPANY
A stable aqueous antiplaque oral composition containing (a) an antibacterial ester compound having the formula (I) where R1 is an alkyl chain of 1 to 8 carbon atoms, and R2 is an alkyl chain of 6 to 30 carbon atoms and X is an anion.(b) a stabilizing surfactant; and (c) a humectant. Methods of making the oral composition are also provided.
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ANTIPLAQUE CONFECTIONERY DENTAL COMPOSITION

(WO2005000255) 06.01.2005 A61K 8/44 COLGATE-PALMOLIVE COMPANY
A confectionery composition delivering antiplaque agents to the oral cavity when applied thereto, the composition being comprised of a homogeneous mixture of a solid base material and an antibacterial ester having the formula (I); wherein R is an alkyl chain of 1 to 8 carbon atoms and R1 is an alkyl chain of 6 to 30 carbon atoms and X is an anion.
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POWER TOOTHBRUSH USING ACOUSTIC WAVE ACTION FOR CLEANSING OF TEETH

(WO2005000150) 06.01.2005 A61C 17/20 KONINKLIJKE PHILIPS ELECTRONICS, N.V.
The toothbrush includes a handle portion and a brushhead assembly which comprises a head portion and a stem portion. The head portion includes a bellows-like acoustic action member for creating acoustic wave action as it moves in and out in response to an acoustic driving force. A drive system is located in the handle and includes an audio speaker-type assembly to create acoustic waves which are transmitted through a transmission line to the acoustic action member. The acoustic action member is driven toward and away from the teeth when the toothbrush is operatively positioned within the mouth. The action of the acoustic member is directly or indirectly coupled to the fluid in the mouth, producing a foam which couples shear forces between t...
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ORAL TREATMENT DEVICES THAT INCLUDE A THIN, FLEXIBLE BARRIER LAYER AND AN ENDOSKELETON TREATMENT OR ADHESIVE COMPOSITION

(WO2005000147) 06.01.2005 A61C 5/00 ULTRADENT PRODUCTS, INC.
Oral treatment devices (100) include a barrier layer (102) and an oral treatment composition (112), and optionally an auxiliary adhesive composition, that acts as an endoskeleton so as to at least partially contribute to maintaining the barrier layer (102) in the shape of a dental tray, or in a tray-like configuration, prior to use. The barrier layer (102) protects the oral treatment (112) and/or adhesive composition from saliva or moisture during use. The treatment and/or auxiliary adhesive compositions (112) can have a consistency ranging from a sticky, viscous gel or a solid. They preferably include a tissue adhesion agent comprising a hydrophilic polymer.
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SLEEP APPLIANCE

(WO2005000142) 06.01.2005 A61F 5/56 KEROPIAN, Bryan, D., D., S.
A dental oral appliance for use with patients who suffer with sleep disorders, to reduce or eliminate snoring and to open the airway for a sleeping individual who suffers with obstructive sleep apnea. The appliance covers the inside (lingual) of the upper teeth and has an open palate. Retention for the appliance is provided by clasps placed over the upper right and left molars and a retainer in the anterior area from cuspid to cuspid. Over the upper central incisors is a raised strip that extends from the incisal tip (biting edge) of the central incisors toward the lingual. It extends back from the middle of the central incisors, where they meet or touch each other, to the middle of the palate. This raised anterior area is to separate the p...
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COMPOSITIONS AND METHODS OF TREATMENT COMPRISING PLANT EXTRACTS

(WO2004112819) 29.12.2004 A61K 35/78 GELSTAT CORPORATION
Methods of treating a disease associated with prolonged or excessive activation of NF-kB are provided, comprising administering a composition comprising at least one plant extract from a plant that is a source of sesquiterpene lactone, or a composition comprising a sesquiterpene lactone in an effective amount to a patient in need thereof. In a preferred embodiment, the plant extract is extracted from feverfew, and the sesquiterpene lactone is parthenolide. In a preferred embodiment of the invention, the composition is administered via a route that bypasses the GI tract. In another preferred embodiment of the invention, the composition is administered in an amount of active ingredient that is surprisingly low.
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PROCESS OF TOOTH WHITENING AND APPARATUS THEREFOR

(WO2004112637) 29.12.2004 A61C 5/06 WASYLUCHA, Bryan
A process of whitening a tooth provided by the invention includes the steps of providing a delivery device for mechanical dispensing of a predetermined amount of a whitening composition to an applicator tip; dispensing the amount of whitening composition to the applicator tip; applying the amount of whitening composition disposed on the applicator tip to the tooth to be whitened; and allowing the whitening composition to remain in contact with the tooth for a period of time sufficient to whiten the tooth. Optionally, the process further includes the step of exposing the whitening composition to light. A gum or candy for tooth bleaching is detailed along with methods of use. A device adapted to dispense an amount of a dental whitening compos...
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HEALTH CONFECTIONERY

(WO2004112491) 29.12.2004 A61K 36/00 SALISBURY, Ashley Carter
The new health food type product is provided having a base composition and a freeze dried component substantially uniformly distributed through the base composition to provide a more nutritious health food product having superior organoleptic properties which more or less last the duration of consumption of the product. The freeze dried product is a fruit, preferably a granulated or powdered fruit which has been produced by a freeze dried process or is snap frozen. The product, as well as having superior nutritional qualities also has increased appeal and overcomes defects associated with existing health food products particularly with regard to mouth feel when being consumed.
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SYNTHETIC RESIN CAP, CLOSING DEVICE, AND CONTAINER-PACKED BEVERAGE

(WO2004110888) 23.12.2004 B65D 41/04 ALCOA CLOSURE SYSTEMS JAPAN, LIMITED
A synthetic resin cap comprising a cap main body having a top plate and a sleeve depending from the peripheral edge of the top plate, the inner surface of the top plate of the cap main body being formed with an annular inner seal projection adapted to be fitted in the container mouth and an annular open end seal projection adapted to abut against the open end of the container mouth, the open end seal projection being deformedly bent in a direction to increase its diameter until it abuts against the cap main body, the top plate being provided with a positioning raised portion disposed such that it abuts against the open end when the open end seal projection is deformedly bent until it abuts against the cap main body; a closing device using t...
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PERCARBOXYLIC ACID-BASED BLEACH COMPOSITIONS HAVING A LONG SHELF LIFE

(WO2004110611) 23.12.2004 A61K 8/11 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
Disclosed are a method for producing gel capsules that are loaded with organic percarboxylic acids, especially imido-percarboxylic acids (e.g. 6-phthalimido-peroxy-caproic acid), and the use of the gel capsules produced according to said method in detergents and cleaners, particularly liquid detergents and cleaners, dental care products, hair dyes, and decolorants or bleaching agents for technical applications.
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NOVEL DEVICE

(WO2004110295) 23.12.2004 A61C 15/04 SMITHKLINE BEECHAM CORPORATION
A dental floss container (20) comprises a base wall (21) and a side wall (22) extending upwardly from the periphery of the side wall (21) to define an open-topped compartment (23) for a spool of dental floss. The side wall (22) extends downwardly below the base wall (21) as a peripheral skirt (25), having a lower edge (26) of the skirt formed into a closure engagement part being a conventional snap-fit part which can snap-fit engage with the ledge of a toothpaste cap. The floss container (20) has a hinged lid (30) for the open-topped compartment (23).
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PET FOOD COMPOSITION

(WO2004110164) 23.12.2004 A23K 1/16 DSM IP ASSETS B.V.
Pet food comprising trisodium L-ascorbic acid-2-monophosphate (STAY-C50) or sodium-calcium L-ascorbic acid- 2-monophosphate (STAY-C35), or mixtures thereof and, optionally, a polymer (for fixation of the ascorbate on the dental surface) and use 5 thereof as additive to pet food for preventing or treating calculus, plaque, gingivitis and periodontal disease and for enhancing the antioxidative capacity in the whole organism.
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AGENTS AGAINST MICROORGANISMS, CONTAINING PATCHOULI OIL, PATCHOULI ALCOHOL AND/OR THE DERIVATIVES THEREOF

(WO2004110153) 23.12.2004 A61Q 5/02 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to agents that contain patchouli oil, patchouli alcohol and/or the derivatives thereof. The invention also relates to the use thereof for inhibiting the asexual reproduction of fungi and for reducing the adherence of microorganisms to surfaces and to filter media, adhesives, building materials and/or auxiliary building materials, especially sealing compounds and adhesives, textiles, furs, paper, skins or leather, but also washing agents, cleaning agents, rinsing agents, textile treating agents, handwashing agents, agents for handwashing dishes, dishwasher agents, building materials and auxiliary building materials, cosmetic and/or pharmaceutical agents, oral, dental or dental prosthesis care products and agents for fin...
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ORAL CEREAL BETA GLUCAN COMPOSITIONS

(WO2004108103) 16.12.2004 A61K 31/716 CEAPRO INC.
The present invention relates to oral compositions comprising a (1-3) (1-4) glucan and one, or more than one compound of interest. In particular, the present invention provides an oral composition comprising an effective amount of a (1-3) (1-4) glucan and an effective amount of one, or more than one of an antibacterial agent, a botanical extract, and a flavouring agent, and also provides a method of using this composition for maintaining fresh breath in a subject over a prolonged period of time.
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A MICRO IMPLANT TORQUE DRIVER FOR LINGUAL ORTHODONTIC TREATMENT

(WO2004108006) 16.12.2004 A61C 1/18 KYUNG, Hee Moon
Our invention shall be related to the micro implant torque driver which will be available for orthodontic treatment. In orthodontic treatment, we will place a micro implant with titanium in an alveolar bone to secure an anchorage and will connect it with an elastic spring to move teeth to another space. But, as the micro implant placed in between teeth has very small size of 1.2mm~1.8mm compared with conventional prosthetic implant (approx 3mm), we would often find small screw broken (mainly body & head parts) in the event of an immoderate stress on the conventional driver. In order to solve such problem, we have developed new torque drivers as followings. The rotation fixer (3) held up by a ball (12) ...
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METHOD AND APPARATUS FOR TOOTH WHITENING

(WO2004108003) 16.12.2004 A61C 1/08 DENTOVATIONS INC.
Preconditioning mouth rinse, which pre-treats the teeth to better receive a whitening formula containing a photosensitive compound, and a hand-held consumer light source (10) for tooth whitening, which provides rapid tooth whitening, are disclosed. The light source may use a specific range of visible light and also emit heat sufficient to raise the temperature of the teeth a desired amount at a depth up to about 2 mm in the range of about from 1 - 5 Celsius over a predetermined period of time.
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CLIP SUNGLASSES FOR CAP/SUNVISOR

(WO2004107022) 09.12.2004 G02C 9/04 SHISENDO CO., LTD.
Clip sunglasses where a flip-up retention angle of a glass lens (4) is adjustable in a stepped manner and is reliably positioned at optimum positions. Clip sunglasses have a clip (1), an insertion member (2), a level-adjusting member (3), and a level-adjusting buckle (5). The clip (1) has a holding mouth (11) and a socket mouth (12) inside which notches are formed at required intervals in the insertion/removal direction. The insertion member (2) has a plug portion formed at one end and fork-shaped clasping brackets (22) formed at the opposite end, and connection holes with internal teeth notches in their inner peripheral surfaces are formed in the clasping brackets (22). The level-adjusting member (3) has connection shafts (31) with stepped...
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SYSTEM FOR SUPPLYING LIQUID OR PASTE-LIKE SUBSTANCES

(WO2004106184) 09.12.2004 B65D 35/28 AKZO NOBEL COATINGS INTERNATIONAL B.V.
The system comprises a compressible bag for receiving the substance to be supplied, a supply assembly which forms a supply channel with a corresponding supply mouth for supplying the substance from the bag, and a container. The container has a supporting body comprising at least a supporting plate and a movable presser plate, wherein the supporting body and the presser plate together form a chamber for the incorporation therein of the bag, so that the bag is positioned between the supporting plate and the presser plate. The presser plate can be moved in a pressure direction to the supporting plate to empty the substance from the bag. The supporting body in a region between the supporting plate and the presser plate is provided with a passag...
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SUBTANTIALLY SOLID DENTAL BLEACHING COMPOSITIONS

(WO2004105683) 09.12.2004 A61C 5/00 ULTRADENT PRODUCTS, INC.
Dental bleaching compositions (10) have a tray-like configuration (12, 14, 16) and comprise a substantially solid bleaching composition that has increased adhesiveness when moistened. The shape of the bleaching composition (10) facilitates placement of the composition (10) over the teeth with less manipulation than the use of flat bleaching strips. The bleaching composition (10) becomes more adhesive when moistened, yet remains intact and coherent after placement over the teeth, particularly when used in combination with a moisture resistant barrier. The bleaching composition (10) is able to reliably adhere against the user's teeth during a bleaching procedure. It may be packaged together as a kit in combination with a desensitizing composi...
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IMPLANT HAVING INTEGRAL FLEXIBLE ABUTMENT PORTION AND METHOD FOR USE THEREOF

(WO2004105632) 09.12.2004 A61B 17/68 POLYDENT MEDICAL DEVICES LTD.
The present invention concerns an implant, in particular a dental implant, having a below-shaped adjustable bendable portion and a cavity extending throughout the bendable portion and having an opening. The invention further concerns a method wherein the implant is placed in the bone, the adjustable bending portion is bended to the desired angle and the cavity is filled with a composition that can fix the portion at a desirable angle.
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DENTAL BLEACHING DEVICES AND METHODS AND KITS THAT UTILIZE SUCH DEVICES

(WO2004105629) 09.12.2004 A61C 5/00 ULTRADENT PRODUCTS, INC.
Dental bleaching devices (10) in the shape of a dental tray or tray-like form include an outer barrier layer (18) and an inner bleaching layer (20). The shape of the dental bleaching device (10) facilitates placement of the device (10) over a person's teeth with substantially less manipulation compared to the use of initially flat bleaching strips. The bleaching layer (20) comprises a substantially solid dental bleaching composition that becomes more adhesive when moistened with saliva or water, yet remains intact and coherent after the dental bleaching device (10) is placed over a person's teeth during bleaching. Because a substantial portion of the dental bleaching composition remains solid or semi-solid during bleaching, the bleaching co...
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SYSTEM AND METHOD FOR UTILIZING FLEXIBLE MEMBRANE DENTAL TRAYS

(WO2004105628) 09.12.2004 A61C 5/00 ULTRADENT PRODUCTS, INC.
A dental treatment system (100) comprises membrane treatment tray (102) that is self-conforming to a person's own teeth when used with a sticky dental treatment composition and a support skeleton (104). The support skeleton (104) maintains the flexible membrane tray (102) in the form of tray prior to placing the tray over a person's teeth. A sticky viscous composition is either provided in or applied to the membrane tray (102), and then the treatment system is placed so as to position the membrane tray over the upper or lower teeth of the person. The support skeleton (104) (internal or external) is separated from the membrane tray (102) so that just the membrane tray (102) remains over the person's teeth during the desired dental treatment....
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TOOTHBRUSH FOR COMPREHENSIVE DENTAL CARE

(WO2004105548) 09.12.2004 A46B 11/00 LAZDINS, Normunds
This invention relates to sanitary and hygienic accessories for comprehensive dental care. The object of this invention is to simplify the construction of a toothbrush, to reduce consumption of materials, to provide reliability and to make it a hygienic one, while increasing the cleaning effect. The toothbrush (Fig.1, 8) comprises a head (1), preferably a rounded one, with cleaning members (2) and an outlet (3) which communicates with the tube (30) of toothpaste through actuating means for feeding toothpaste under pressure, the said actuating means are made from moulded plastics in the form of an integral body of a ball (7) with through opening forming the outlet (8) and circular slot (10) for passing of rigid neck (12) into it by a pop-in ...
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(METH)ACRYLIC ESTER COMPOUND AND USE THEREOF

(WO2004103949) 02.12.2004 C07C 69/54 MITSUI CHEMICALS, INC.
A (meth)acrylic ester compound represented by the general formula (1): (wherein R11 represents a divalent aromatic group; R12 represents hydrogen or methyl; R13 represents aryl; R14 represents hydrogen or methyl; and X11 represents oxygen or sulfur); and a dental material containing the compound. The dental material and dental composition which each contains the compound represented by the general formula (1) are useful because they have excellent curability and combine transparency, suitability for roentgenography, and low polymerization shrinkage while retaining various properties required of dental materials (e.g., flexural strength). A polymerizable composition containing the (meth)acrylic ester compound represented by the general formu...
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PATCH FOR TOOTH WHITENING

(WO2004103328) 02.12.2004 A61K 6/00 ICURE PHARMACEUTICAL CORPORATION
The patch for tooth whitening of the present invention comprises a tooth-adhering layer (1) containing erodible polymer complexes formed by hydrogen bonding of a polymer with a carboxyl group (-COOH) and a polymer with a carbonyl group (-C=O) or ether group (-O-) and a tooth whitening agent; and an erosion rate-controlling layer (2) containing a mixture of a hydrophilic polymer and a film-forming polymer, wherein the patch is in a film form and is characterized by being eroded until extinguished after releasing the tooth whitening agent. The patch, when applied to the teeth, releases a peroxide tooth-whitening agent while being hydrated by water in the mouth during a prescribed period, and thereafter, eroded until extinguished, there...
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THERAPEUTIC DENTAL COMPOSITION

(WO2004103303) 02.12.2004 A61K 8/00 BRITESMILE DEVELOPMENT, INC.
A solid or semi-solid oral therapeutic dental composition comprising a therapeutic agent dispersed in a water-insoluble or water-resistant carrier. The dental composition may be in the form of a crayon or dispensed from a delivery device such as a pen or the like.
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METHOD AND DEVICE FOR COATING TOOTHPICKS OR FLOSSERS AND CORRESPONDING TOOTHPICKS AND FLOSSERS

(WO2004103204) 02.12.2004 A61C 15/02 BRAUN GMBH
The invention relates to a method and a device for coating an interdental cleaning element that penetrates the space between the teeth, for example, a toothpick (1) made of plastic or a flosser (37). The method involves the following steps: tempering the cleaning elements (1, 38) to a predefined temperature; dipping the cleaning elements (1, 38) in a dip bath (7) that is filled with a coating agent (18); placing the cleaning elements (1, 38) in a drip zone by means of a air flow (20) to superficially remove wax and placing the cleaning elements (1, 38) in a cooling zone to allow the coating to harden. The inventive method makes it possible to obtain a coating with constant quality, which has an effect within a short time in the mouth of the...
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ENDOSCOPIC BITE BLOCK

(WO2004103199) 02.12.2004 A61B 19/00 ORIDION MEDICAL (1987) LTD.
An endoscopic bite block, with teeth position defining regions which guide the subject's teeth to grip the bite block in their natural position, with the teeth of the upper jaw positioned further out than the lower jaw teeth. These teeth position defining regions are also preferably curved to match the curved shape of the jaw. The upper and lower parts of the front plate of the bite block may also be positioned at different distances out, so that upper and lower lip regions both contact the front plate snuggly. The bite block may be used with separate oral/nasal cannulae, or may incorporate breath sampling or gas supply cannulae. A flexible flapped curtain at the outer end of the bite block may be provided to largely enclose the inner volum...
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MULTIPHASE TOOTHPASTE COMPOSITION

(WO2004100913) 25.11.2004 A61K 8/19 UNILEVER N.V.
A multiphase toothpaste comprising an opaque phase and a transparent gel phase, each said phase having a mobile phase with an effective amount of cleansing or polishing agents suspended therein, and wherein of the ingredients making up more than 2% of each mobile phase a corresponding amount of said ingredients is present in the other mobile phase such that no substantial transfer of ingredients occurs between the mobile phases.
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MECHANICAL TOOTHBRUSH WITH THE LONGITUDINAL AXIS OF MOTION PROTRUDING ON BOTH SIDES OF THE STEM

(WO2004100823) 25.11.2004 A61C 17/24 ZELIANAIOS, Loukas
The mechanical toothbrush with the longitudinal axis of motion passing through and protruding on both sides of the stem, comprises the stem (2), (21a) and (21b) which is a divided holster, inside which is assembled and functions the proposed manual mechanism that provides the rotation, the longitudinal axis of motion (1) which passes through and protrudes, through its end parts (1a) and (1b), on both sides of the stem (2), (21a) and (21b) and the two cleaning heads (12a) and (12b) and is characterized by the fact that even though the longitudinal axis of motion (1) has a single direction of rotation, it produces a clockwise or a counter-clockwise rotation of the cylindrical cleaning heads (12a) and (12b) in relation to the dental surface be...
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RESUSCITATION TRAINING MANIKIN

(WO2004100107) 18.11.2004 G09B 23/28 LAERDAL MEDICAL AS
A manikin for practising resuscitation, comprising an inflatable body (1). The inflatable body (1) is adapted to absorb compression force exerted during simulated chest compression. Preferably, the manikin also comprises a chest plate (4), the chest plate (4) acting as a pressure distributor on the inflatable body (1). The chest plate (4) being connected to the inflatable body (1) by elastic means (22). The manikin may also comprise a lung part (2), the lung part being connected to a face mask (3). The lung (2) being adapted for inflation through the mouth and/or the nose of the face mask (3). The lung (2) having a chest portion ( 13) positioned substantially parallel to the chest portion (5) of the inflatable body (1). The face mask (3) be...
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SOLID PHASE CELL LYSIS AND CAPTURE PLATFORM

(WO2004099384) 18.11.2004 C12M 1/40 SIGMA-ALDRICH CO.
The present invention provides containers, processes, and kits relating to the extraction or the extraction and isolation of a cellular component from a host cell. More specifically, the containers of the invention comprise a mouth; an interior surface comprising a sidewall formation and a bottom; a volume; a lytic reagent; and in some instances, a supported capture ligand. Methods and kits for the extraction or the extraction and isolation of a cellular component from a host cell using the containers described herein are also provided.
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DENTAL CEMENT COMPOSITION

(WO2004098541) 18.11.2004 A61K 6/06 UM DENTAL CO., LTD.
A dental cement composition which comprises: inorganic particles containing a polyvalent-metal compound; and an organic polymer. The organic polymer comprises units (A) containing a (substituted) carboxy group which are represented by the formula (I) and units (B) containing a (substituted) carbamoyl group which are represented by the formula (II). In the organic polymer, the sum of the two kinds of units accounts for at least 20 mol% of all units, and the proportion of (A)/(B) is from 0.6/1.0 to 1.0/0.6. In at least 70 mol% of the units (A) or (B) which are minor units between the two kinds of units, the (substituted)-carboxy-bonded carbon is adjacent to the (substituted)-carbamoyl-bonded carbon either directly or through a methylene or et...
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METHOD FOR PRODUCING ADHERENT COATINGS

(WO2004098436) 18.11.2004 A61C 8/00 NEW YORK UNIVERSITY
A method for forming a highly adherent coating of a desired calcium phosphate phase on titanium-based substrates for use as orthopedic and dental implants. The calcium phosphate phase coating is electrochemically deposited onto the substrate from a metastable calcium phosphate electrolyte solution using a modulated electrical potential under pH, temperature and electrolyte composition and concentration conditions favorable for forming the desired calcium phosphate.
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METHOD OF DIAGNOSIS OF FOOT AND MOUTH DISEASE AND THE DIAGNOSTIC KIT

(WO2004097418) 11.11.2004 G01N 33/52 REPUBLIC OF KOREA (NATIONAL VETERINARY RESEARCH AND QUARANTINE SERVICE)
The present invention provides a method for diagnosing foot- and -mouth disease virus infection, comprising the steps of applying a predetermined amount of a test sample to a loading region of a strip; coupling a detection reagent including a given labeling reagent to an analyte of interest in the test sample to form a complex therebetween; developing the complex onto a wicking membrane; and observing changes in appearance of a reactivity zone having at least more than one immobilized phase selected from antigen, antibody or hapten on the predetermined region of the wicking membrane, derived from FMDV or obtainable from FMDV through an immunological reaction to determine the presence or absence of foot- and -mouth disease virus infection. I...
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MATERIAL FOR INHIBITING ENAMEL DECALCIFICATION

(WO2004096165) 11.11.2004 A23G 3/00 ASAHI BREWERIES LTD.
It is intended to provide an effective cariostatic material which inhibits dental plaque formation as well as onset of dental caries. A material for inhibiting enamel decalcification containing, as the active ingredient, a proanthocyanidin-like polyphenol originating in hop bract or immature apple, which effectively inhibits not only dental plaque formation but also the dental caries process including proliferation of bacteria, formation of acids by the bacteria and enamel decalcification. Also, foods, drinks and oral care goods with the use of the above substance as an enamel decalcification inhibitor are provided.
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BREATHING NORMALIZER APPARATUS

(WO2004096084) 11.11.2004 A61F 5/56 PIVOVAROV, Alexander
A breathing normalizer (10) for partial insertion within the user's mouth to normalize breathing patters, and to prevent snoring, teeth grinding, and light forms of sleep apnea is disclosed. A breathing normalizer includes: an outer shield (30) positioned external to the user's mouth which in user, an elongated hollow shaft (16) for connecting outer shield (30) to a lip plate (18), that is adapted to be received between the users lips and teeth and a generally C-shaped multi-lobed structure (12) adapted for receiving the users tongue.
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A FLAMELESS ELECTRONIC ATOMIZING CIGARETTE

(WO2004095955) 11.11.2004 A24F 47/00 HON, Lik
The invention relates to a non-smokable electronic spray cigarette which only comprises nicotine without harmful tar.The cigarette includes a smoke mouth integer comprised with a shell, a cell, a high frequancy ionzer, nicotine solution storage and its container, control circuit, a display screen , a human contact sensor, a piezoelectric supersound atomizer, a high temperature vaporazation nozzle and attachments, a electrothermal vaporazation nozzle installed in the air suction end of the shell goes though a electric control pump or a valve with a measuring chamber and a liquid storage capsule which installs nicotine solution and is connected to the electric control pump or valve with an one-way flow valve, the control circuit plate has fou...
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COMPOSITION CONTAINING BERBERINE OR A DERIVATIVE THEREOF AND AN ANTIMICROBIAL AGENT OR AN ANTIBIOTIC AGENT, AND THEIR USE FOR TREATING ORAL PATHOGENS AND OTHER DISORDERS

(WO2004093876) 04.11.2004 A61K 31/155 THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
A composition and method of controlling oral and other human pathogens is disclosed. The composition and method utilize an antimicrobial or antibiotic and a berberine as active agents to treat mammals, including humans.
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USE OF GLYCODENDRIMER REAGENTS FOR INHIBITING ADHESION BY MICROORGANISMS

(WO2004093787) 04.11.2004 A61K 38/48 GENENCOR INTERNATIONAL, INC.
The present invention is directed to glyodendrimeric proteases, composition with glycodendrimeric proteases and methods for inhibiting adhesion binding in microorganisms by contacting microorganisms with a glycodendrimeric protease or a composition with a glycodendrimeric protease. The invention may be used to treat patients in need of treatment.
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TOOTHPASTE DISPENSING DEVICE

(WO2004092031) 28.10.2004 B65D 35/22 GREEN, Basil, Martin
This invention relates to a toothpaste dispensing device (140) which includes an elongate container body (142) having at least two compartments (144, 146) containing dentifrice compositions and at least two discharge openings (148) defined in the body (142), a discharge opening (148) being provided in flow communication with each compartment (144, 146). The device (140) includes closure means (150, 152) for independently selectively opening or closing the at least two discharge openings (148) thereby to permit the dentifrice composition contents of the at least two compartments (144, 146) to be dispensed separately.
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HUBCAP FOR VEHICLE WHEELS

(WO2004091935) 28.10.2004 B60B 7/00 ZANINI AUTO GRUP, S.A.
The invention relates to a hubcap (1) comprising tubular projecting elements (2) with flexible tabs which are guided to a pressing position by means of a metal ring or strip and are provided with a lip (4) having a stop step (8) on their free border for a projection (7) pertaining to the head of the fixing bolts (6) of the wheel rim. The novelty of the intention is that an additional part (9) is mounted in a tight and pressurized manner in each of the tubular projecting elements (2), said part serving as centering means and as means for covering the grooves defined by the flexible tabs of said tubular projecting element (2). Said additional part (9) has projections (10) for engaging in the stops (11) of the tubular projecting element (2) an...
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BONE GROWTH STIMULATION WITH NO/STATIN AND OTHER NO MODULATING COMBINATIONS

(WO2004091626) 28.10.2004 A61K 31/195 OSTEOSCREEN, INC.
Methods and compositions provided herein relate to the promotion of bone formation and are thus useful in treating osteoporosis, bone fracture or deficiency, primary or secondary hyperparathyroidism, periodontal disease or defect, metastatic bone disease, osteolytic bone disease, post-plastic surgery, post-prosthetic joint surgery, and post-dental implantation. Disclosed is a method of enhancing bone formation by administering at least two components selected from at least one statin-like compound, at least one nitric oxide generating system, and at least one phosphodiesterase inhibitor. Also disclosed is a pharmaceutical composition comprising said at least two components.
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ORAL COMPOSITION FOR STABILIZATION,(RE)CALCIFICATION AND (RE)MINERALIZATION OF TOOTH ENAMEL AND DENTINE

(WO2004091564) 28.10.2004 A61K 8/19 BASIC, Robert
Technical problem the inventor faced, concerns the finding of the oral composition for the stabilization, (re)calcification and (re)mineralization of dental enamel, and in that way, create an efficient protection from the tooth decay. The solution to this technical problem is based on the use of calcium form of zeolite, phosphate salts soluble in water and matrix proteins of teeth. The efficiency of this solution is based on the adjustment of pH in the mouth cavity to the required value while at the same time incorporating the calcium ions from the calcium form of zeolite into the dental enamel and dentine in the presence of matrix proteins of the teeth. The invention, with its entire effect, substitutes the calcium and phosphate ions in th...
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DEVICE FOR CLEANING INTER-DENTAL SPACES

(WO2004091425) 28.10.2004 A46B 7/02 LESAGE, Patrick
The invention relates to a device for cleaning inter-dental spaces, comprising a tubular guide element (32) with a first open profiled end (40) which permits the positioning thereof at the entrance to an inter-dental space, cleaning means (36), mounted to move within the tubular element, fixed to a first end of support means (58), support means (58) for the cleaning means (36) with a longitudinal direction fixed with relation to the axis of the tubular element and grip means (34) for moving the cleaning means (36) between a first position in which said means are entirely located within the tubular element (32) and a second position in which said means are entirely located outside the first end of the tubular element.
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TOOTHBRUSH

(WO2004091341) 28.10.2004 A46B 11/00 SOLOMON, Allen, Joe
A tooth brush comprises a tubular body (10) forming a handle, an elongate stem (14) projecting from one end of the tubular body and having a brush head (16) at its outer end, the tubular body having a compartment (24) containing toothpaste and means being provided for delivering toothpaste from the compartment (24), through the stem (14) and to the brush head (16).
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METHOD FOR PREPARATION OF A FOOD SAUCE

(WO2004091311) 28.10.2004 A23L 1/238 WELCH FOODS INC.
A method for preparation of a food sauce having a fresh fruit suspension. The method disclosed by the invention involves manipulating the pre-gel of a low methoxyl pectin by various processing steps and ingredient additions. The end product provides a sauce having a fresh fruit flavor with a unique texture and mouth feel.
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FLOOD CONTROL AND WATER SUPPLY SYSTEM USING TIDE GENERATOR BY SEA HOLLOW (UTSURO)

(WO2004090235) 21.10.2004 E02B 3/02 AKAI, Kazuaki
Sea hollow (UTSURO) is part of a water area surrounded and enclosed by a bank structure in a tide-level-changing water area. By using a tide generator by a sea hollow (UTSURO) which spreads a canal mouth that opens a sea hollow (UTSURO) water area via a canal toward a rivers upstream part to open it in a tide-level-changing river-upstream water area, the functional extension of a rive is shortened, a river bed gradient is steepened, the flow rate and the tractive force of a river are increased, a river bed is deepened, a river section area is enlarged, and a drainage of inner basin and a flood discharge capacity are increased. At a downstream part, the size of sea hollow (UTSURO)...
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DENTAL COMPOSITION FOR PROMOTING BONE REGENERATION

(WO2004089332) 21.10.2004 A61K 6/06 ITALMED DI GALLI GIOVANNA E PACINI GIGLIOLA S.N.C.
Dental composition comprising at least one calcium salt, at least one essential amino acid and sodium alginate. The calcium salt can be selected from the group of calcium phosphates, calcium carbonates, or a mixture thereof. Between the calcium phosphates monocalcium phosphate is preferred, whereas the sodium alginate can have either low or intermediate viscosity sodium alginates, i.e. having a viscosity of a 2% solution respectively of 250 and 3500 cps or intermediate values between them. The composition is extremely effective, in particular osteconductor, osteinductive; well tolerated, i.e. biocompatible/ biotolerable / easily absorbable; simply usable, i.e. with good manipulation/ mechanical features; easy, i.e. that can be used in vario...
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DENTAL ADHESIVE AND DENTAL FILLER

(WO2004089314) 21.10.2004 A61K 6/00 UM DENTAL CO., LTD.
A dental adhesive composition which contains an organic polymer comprising units (A) containing a (substituted) carboxy group which are represented by the formula (I) and units (B) containing a (substituted) carbamoyl group which are represented by the formula (II). In the organic polymer, the sum of the two kinds of units accounts for at least 20 mol% of all units, and the proportion of (A)/(B) is from 0.6/1.0 to 1.0/0.6. In at least 70 mol% of the units (A) or (B) which are minor units between the two kinds of units, the (substituted)-carboxy-bonded carbon is adjacent to the (substituted)-carbamoyl-bonded carbon either directly or through a methylene or ethylene group.
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FLOWER HOLDER STRUCTURE

(WO2004089170) 21.10.2004 A47G 7/06 LA GRECA, Gaetano
The present invention relates to a flower holder structure (1), particularly suitable for supporting and exhibiting flowers (F) and similar ornaments, being they long-stemmed or long-stalked, dry of freshly-cut, comprising a first base plate (2), a plurality of stiff elongate connecting elements (3), which are removably associated, at one end (3a) thereof with said first base plate, all of them projecting on the same side with respect to said base plate (2), and which are removably associated, at their other end (3b), with a second plate (4), in order to form a substantially basket-like holder, said second plate (4) having at least one hole (4a) passing therethrough, forming the mouth of said substantially basket-like holder.
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NICOTINE SUCTION PIPE AND NICOTINE HOLDER

(WO2004089126) 21.10.2004 A24F 47/00 TAKANO, Shusei
A nicotine suction pipe, comprising a bar-like nicotine holder (1) and a mouth piece (2) fitted to one end of the holder (1), the holder (1) further comprising a transparent outer tube (3) having a plurality of openings (36) at both ends thereof, liquid absorbing particles (34) filled in the outer tube (3), and a nicotine suction route formed of clearances between the liquid absorbing particles (34) and clearances between the inner peripheral surface of the outer tube (3) and the liquid absorbing particles (34). The liquid absorbing particles (34) are formed of porous silica gel, absorb nicotine solution, and allows the vaporization of nicotine from the nicotine solution.
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DENTAL FURNACE FOR PRODUCING COMPACTED CERAMICS

(WO2004085943) 07.10.2004 A61C 13/20 ZUBLER GERTEBAU GMBH
The aim of the invention is to provide a reliable and efficient operation of a dental furnace (1) for producing compacted ceramics, comprising a hood-shaped firing chamber (3), into which a muffle (5) can be inserted and which is closed during operation by a bottom plate (4), and a pneumatic cylinder (10) whose working pressure can be adjusted by a pressure reducer is mounted on the firing chamber (3). To this end, the invention provides that at least two pressure reducers (9a, 9b) are each provided with a different working pressure or the pressure reducer is provided in the form of a proportional pressure regulator with electronically controllable different working pressures. The pressure reducers (9a, 9b, ) or the proportional pre...
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NONTOXIC DENTAL CARE HERBAL FORMULATION FOR PREVENTING DENTAL PLAQUE AND GINGIVITIS

(WO2004084852) 07.10.2004 A61K 8/97 COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
The present invention relates to a synergistic herbal formulation comprising an active fraction from Azadirachta indica designated as Fraction A and a fraction from Citrullus colocynthis designated as Fraction B, along with a fraction C containing an antioxidant from Cucumis sativus extract; and pharmaceutically accepted a carrier wherein the ratio of the components ranging between about 2 to 5.5 % of fraction A; about 0.5 to 2.5 % of fraction B; about 0.1-0.4 % of extract of Cucumis sativus; and about 82-97 % of carrier or additive.
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A TREATMENT COMPOSITION

(WO2004084851) 07.10.2004 A61K 6/00 EXA SA
The invention relates to a dental treatment composition comprising a particulate erasing agent, the particles of the erasing agent being dimensioned to roll along a surface. The particles have an average maximum diameter of between 30 and 1000 microns and consist of a precipitate of calcium carbonate. As the particles are round, when applied 12 to a dental surface the particles roll along the surface picking up debris, stains, plaque, tartar or the like from the surface without damaging the dental surface. A method of treating teeth which employs a dental treatment composition of the invention is also disclosed.
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A DENTAL TREATMENT COMPOSITION

(WO2004084850) 07.10.2004 A61K 6/00 EXA SA
A dental treatment composition comprises a particulate erasing agent having particles which are dimensions to roll along a surface. The composition has at least 3% water and the particulate erasing agent comprises a precipitate or agglomerate of an insoluble alkali metal carbonate. The composition may be a toothpaste, a toothgel, a polishing paste or an additive powder. A method of treating teeth to remove dirt, debris, stains or the like which employs a composition according to the invention is also described.
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DENTAL CLEANING DEVICE

(WO2004084759) 07.10.2004 A61C 15/02 TAYLOR, Hatib, Donald
A cartridge (1) for releasable engagement with a dental cleaning device (5) comprises a dental cleaning tool (3) and holding means (2a, 2b) for holding the dental cleaning tool (3). The holding means (2a, 2b) have resilient engagement means (4) for engaging the dental cleaning device (5).
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INTRAORAL X-RAY SENSOR

(WO2004084730) 07.10.2004 A61B 6/14 KALTENBACH &VOIGT GMBH &CO. KG
The invention relates to an intraoral sensor for a dental x-ray device. Said sensor comprises a detection element (2) for detecting X-rays, which is arranged inside a housing (1). The housing (1) or parts thereof is made of an abrasion-resistant material, especially porcelain, ceramic, enamel, metal or a combination of said materials in order to improve the cleaning and sterilisation options of said sensor. In order to prevent damage by external jolts or shocks to the detection element (2), said element is arranged on top of one or several damping element (10) inside the housing (1)
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A PREPARATION METHOD OF IgY FOR PREVENTING AND CURE MOUTH DISEASE AND THE TOOTHPASTE BASE ON THE IgY

(WO2004083246) 30.09.2004 A61Q 11/00 JASON MEDICAL GROUP (FAR EAST) LIMITED
The present invention relates to a preparation method of IgY for preventing and cure mouth disease, and a safe toothpaste contain the IgY.
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DENTAL DEVICE FOR RECORDING THE POSITION OF THE JAWS OF A PATIENT IN RELATION TO ONE ANOTHER BY MEANS OF RECORDING PLATES

(WO2004082516) 30.09.2004 A61C 19/05 DENTALGERTE 'CONDYLATOR', GERBER, Peter, T.
The invention comprises a pair of one-piece, flat recording plates that are mirror symmetric about a sagittal plane S, of which an upper part (200), which is provided with a stylus (202), can be affixed to the upper jaw of the patient, and a lower part (100), which is provided with a writing surface (101), can be affixed to the lower jaw of the patient. A recording plate comprises a planar base area (110; 210), planar transition areas (113, 114; 213, 214), which border thereon, and supporting surfaces (111, 112; 211, 212), which border on the latter and which have continuous retention openings (119; 219). The base area is approximately shaped in the form of a forward tapering isosceles trapezoid, which is mirror symmetric about the sagittal...
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DENTAL SET AND SULCUS RETRACTION METHOD

(WO2004082510) 30.09.2004 A61C 9/00 COLTENE AG
The invention relates to a sulcus retraction method which is characterized by producing in a first step a dental impression (8) using a curable composition (3) which is removed after curing. A silicone material (5) is applied in the border area between the tooth (1) and the marginal gingiva (2) using an appropriate tool. The silicone material (5) is characterized in that it expands volume-wise when curing. The dental impression (8) previously produced is again placed on the teeth, whereby this impression (8) constitutes a unilateral limitation for the direction of expansion of the silicone material (5).
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ORAL AND DENTAL CARE AGENT

(WO2004080434) 23.09.2004 A61K 8/21 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to oral and dental care agents, containing: an active ingredient combination (A) of at least one cationic component with an anti-bacterial action, (B) at least one active ingredient with an anti-tartar action, selected from the group of azacycloalkane diphosphonic acids or their physiologically compatible salts and (C) at least one binding agent, selected from xanthan gum, carboxymethylcellulose or a mixture of said two components. The oral and dental care anti-bacterial agents do not cause the discoloration associated with chlorohexidine and reduce or prevent discoloration to human teeth. This is unique for oral and dental care agents based on chlorohexidine. The inventive oral and dental care agents also have a tarta...
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USE OF REPEAT SEQUENCE PROTEIN POLYMERS IN PERSONAL CARE COMPOSITIONS

(WO2004080426) 23.09.2004 A61K 8/64 DOW CORNING CORPORATION
A personal care composition is provided and includes an effective amount of a repeat sequence protein polymer. The personal care composition may be a hair care composition, a skin care composition, a nail care composition, a cosmetic composition, or an over-the-counter pharmaceutical composition.
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FACE MASK WITH SEAL AND NEUTRALIZER

(WO2004080219) 23.09.2004 A62B 18/08 MATICH, Ronald, D.
A sealed face mask (10). The face mask (10) includes a periphery (18) with a seal (12) that surround the nostrils and the mouth that sticks to the skin. The adhesive of the seal (12) may be a skin friendly adhesive or a skin unfriendly adhesive. With the skin unfriendly adhesive, the adhesive includes a strength sufficient to remove a first layer of skin from the face when the seal (12) is pulled from the face. The seal (12) includes a strip that may be elastomeric. The periphery (18) of the face mask (10) may be elastomeric. The face mask (10) includes a neutralizing agent (16) to minimize harmful effects of substances passing through the face mask (10). Also disclosed is a method for fixing the face mask (10) to the face.
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IMMUNOLOGIGAL MARKERS

(WO2004078926) 16.09.2004 A01K 11/00 BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY
Compounds, compositions and methods for identifying human or other animals having a particular characteristic, by administration of an antigenic marker that elicits a unique antigenic response. Compositions comprise: (a) an antigenic marker; and (b) a pharmaceutically-acceptable carrier wherein said marker does not elicit a vaccination immune response. In a preferred embodiment, the composition additionally comprises a vaccination antigen effective against organisms such as Mycobacterium, human immunodeficiency virus (HIV), 10 hepatitis C, Espstein-Barr virus, cytomegalovirus virus, E. coli, feline leukemia virus, foot-and-mouth virus, and canine distemper virus. The present invention also provides methods for tracking a subject having a gi...
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A POYMERIZABLE PHOSPHORIC ACID ESTER DERIVATIVE AND A DENTAL COMPOSITION EMPLOYING IT.

(WO2004078100) 16.09.2004 A61K 6/00 DENTSPLY DE TREY GMBH
The present invention provides a polymerizable phosphoric acid ester derivative having the following formula (A): wherein Z is COOR1, COSR1, CON(R1)2, CONR1 R2, or CONHR1, R1 and R2 independently are a hydrogen atom, a substituted or unsubstituted C1 to C18 alkyl group optionally substituted by a C3 to C8 cycloalkyl group, a substituted or unsubstituted C3 to C8 cycloalkyl group, a substituted or unsubstituted C4 to C,18 aryl or heteroaryl group, a substituted or unsubstituted C5 to C18 alkylaryl or alkylheteroaryl group, or a substituted or unsubstituted C7 to C30 aralkyl group, whereby two R1 residues may form together with the N-atom to which they are bonded a 5- to 7-membered heterocyclic ring which may contain beside said N-atom a furt...
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MEDICAL EQUIPMENT FOR CREATING A SURGICAL SPACE FOR ORAL SURGERY

(WO2004078046) 16.09.2004 A61B 1/24 KARL STORZ GMBH &CO. KG
The invention relates to a medial equipment (10) for creating a surgical space in the human or animal body for minimally invasive oral surgery. Said equipment comprises a shaft (26) which can be introduced through an incision in the cheek, and a plate-shaped flat element (28) which can be introduced through the mouth. The equipment is characterized in that a distal end of the shaft (26) and the plate-shaped element (28) are provided with a connecting mechanism which is adapted to fixate the plate-shaped element (28) on the shaft (26).
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FOAMABLE WATER-IN-OIL TYPE EMULSION COMPOSITION

(WO2004077955) 16.09.2004 A23D 7/005 KAO CORPORATION
A foamable water-in-oil type emulsion composition containing fats comprising one or more diglycerides and a liquid sugar, wherein (a) the fats have a solid-fat content at 25C of 0.5 to 5%, (b) the content of C16-18 unsaturated diglycerides in the fats is 40 wt.% or higher, and (c) the proportion of the fats to the liquid sugar is from 1/0.5 to 1/4. The composition has satisfactory meltability in the mouth and satisfactory shape retention at room temperature. It further has a low specific gravity and gives an excellent feeling in the mouth.
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CROSSLINKABLE POLYMERIC MATERIALS AND THEIR APPLICATIONS

(WO2004075862) 10.09.2004 A61C 8/00 ASHMAN, Arthur
The present invention relates to a novel composition for dental, orthopedic and drug delivery purpose. Specifically, it relates to composition comprising an admixture of a resorbable bone substitute and a crosslinkable prepolymer. It also relates to the composition formed by crosslinking the admixture.
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MULTIPLE USE DENTAL VISCOUS MATERIAL DISPENSER

(WO2004075851) 10.09.2004 A61C 5/06 CONFI-DENTAL PRODUCTS CO.
A viscous material dispenser, and dispenser system and kit, can include a dispenser without a dispensing tip and one or a plurality of separate dispensing tips that are removably attachable to the dispenser. The dispenser can be used with many different types of viscous material containing capules and cartridges, such as those containing composites, dental cements, glass ionomers and the like. In embodiments, the dispenser can incorporate an integral activator for multi-component composition cartridges, such as glass ionomer cartridges.
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ANTI-SENSITIVITY, ANTI-CARIES, ANTI-STAINING, ANTI-PLAQUE, ULTRA-MILD ORAL HYGIENE AGENT

(WO2004075770) 10.09.2004 A61K 8/55 RHODIA INC.
This invention relates to a composition useful as a dentifrice comprising a surfactant agent consisting essentially of monoalkyl and dialkyl phosphate esters, wherein the ratio of monoesters to diesters is greater than 1, and optionally an abrasive agent consisting essentially of siliceous materials.
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A STEREOTACTIC LOCALIZER SYSTEM WITH DENTAL IMPRESSION

(WO2004075716) 10.09.2004 A61B 19/00 SHERWOOD SERVICES AG
Dental-based stereotactic localizers for non-invasively inducing computer tornographic (CT) slice images of the anatomy of a patient are disclosed. The localizer includes a dental piece configured and adapted to be received in the mouth of the patient, a support structure secured to the dental piece, the support structure defining an arcuate configuration which extends to the posterior margins of the teeth of the patient thus allowing an occipital region of the head of the patient to directly contact a surface of a treatment table, and a plurality of graphic reference elements, wherein the plurality of graphic reference elements produce index information on an image scan when intersected by a plane of a scan slice, wherein the index informa...
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TOOL FOR FIXING AND CLEANING PAPER TAPE ON A DRYWALL

(WO2004074598) 02.09.2004 B28B 11/08 SANDOVAL PINTO, Evaristo
The invention relates to a tool which is used to fix paper tape and clean off excess cement on a drywall. Said tool consists of a rim, a compartment or container which is used to store excess material, a container mouth or inlet and a grab bar or handle comprising a screw thread such that an extension tube can be fitted thereto for areas out of arms' reach. The invention has been designed to facilitate the above-mentioned operations and to enable same to be performed in less time, dispensing with the need for scaffolding or ladders. The inventive tool can be made from polypropylene plastic using a mould made from metal in the plastic injection system for the mass production of the tool or using stainless steel sheet metal which is reinforce...
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IMPROVEMENTS IN OR RELATING TO FLAVOUR COMPOSITIONS

(WO2004073672) 02.09.2004 A61K 8/33 QUEST INTERNATIONAL SERVICES B.V.
A flavour composition comprises at least 0.5 % by weight of one or more of the following group A materials: cinnamic aldehyde, basil oil, tarragon, cis-3-hexenyl acetate, cis-3-hexenol, orange oil, lime, citral, and damascone; and at least 3 % by weight of one or more of the following group B materials: anethole synthetic, alcohol C10, eucalyptol, methyl salicylate, clove bud oil, carvone laevo, benzyl benzoate, thymol, benzaldehyde, benzyl formate, ethyl salicylate, eucalyptus oil, ionone alpha, iso amyl acetate, rosemary oil, cardamom oil, ginger, eugenol, camomile oil, spearmint, and peppermint. These materials have been identified as being capable of inhibiting the growth of Porphyromonas gingivalis or the protease (arg-gingipain) a...
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FLAVOURED MOUTH WASH COMPOSITION

(WO2004073671) 02.09.2004 A61K 8/19 QUEST INTERNATIONAL SERVICES B.V.
The present invention provides a flavoured product comprising four or more flavour materials having antimicrobial properties and selected from the group comprising nonanol, decanol, nonanal, decanal, amyl propionate, anethole synthetic, anisic aldehyde, basil oil, benzyl benzoate, benzyl butyrate, benzyl formate, camomile oil, cinnamic aldehyde, cis-3-hexenol, clove bud oil, damascone, ethyl acetoacetate, eucalyptus oil, ginger, isoamyl acetate, menthol laevo, methyl cinnamate, methyl salicylate, orange oil, rosemary oil, tarragon, Tea Tree oil, and peppermint oil; and one or more antimicrobial agents selected from the group comprising triclosan, pyrophosphates, zinc salts, cetylpyridinium chloride, parabens, stannous salts, sodium dodecyl ...
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IMPROVEMENTS IN OR RELATING TO FLAVOUR COMPOSITIONS

(WO2004073670) 02.09.2004 A61K 8/33 QUEST INTERNATIONAL SERVICES B.V.
A flavour composition comprising at least two flavour materials selected from the following Group (a) materials: decanol, nonanol, decanal, anethole synthetic, cardamom oil, cinnamic aldehyde, ionone alpha, origanum, tarragon, thymol; and at least one flavour material selected from the following Group (b) materials: nonanal, Aniseed rectified, basil oil, camomile oil, citral, clove bud oil, Damascone F, ginger, Tea Tree Pure, peppermint oil of natural origin. The compositions may reduce or prevent dental caries.
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SELF-ETCHING PRIMER AND ADHESIVE BONDING RESIN

(WO2004073660) 02.09.2004 A61K 6/00 BISCO, INC.
Stable self-etching copolymerizable primer compositions including are provided including compounds having a polymerizable ethylenically unsaturated groups and acidic groups, and optionally comonomers and suitable solvents. Such compositions are used in conjunction with dental adhesives to provide one or multi-component dental systems capable of etching or decalcifying tooth dentin and enamel without the need for a separate rinse step. Methods of use of such compositions according to the present invention include application for priming and imparting enhanced adhesion between the primers, adhesives, and the tooth substrates such as dentin or cut or uncut enamel, and subsequently applied dental composites, restoratives or other dental compone...
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TOOTHBRUSH AND TOOTHPASTE HOLDER

(WO2004073475) 02.09.2004 A47K 5/18 KIM, Young-Chan
A toothbrush and toothpaste holder of the type that has two different cylindrical-shapes of which one side is a usual cup shape where a toothpaste can be stored while the other side that the cylinder has higher degrees of taper and shrinking down to the bottom where is open but has a cone shaped post with eight dividers that could hold eight toothbrushes in a sanitary position automatically by gravity.
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PRECIPITATED CALCIUM CARBONATE

(WO2004071450) 26.08.2004 A61K 8/19 J.M. HUBER COROPORATION
An abrasive precipitated calcium carbonate is provided that provides excellent cleaning properties without being excessively abrasive or damaging to gums or tooth surfaces. The abrasive, precipitated calcium carbonate has a primary particle size of about 1 m to about 4 m, and an aggregate size of about 3 m to about 10 m. Also disclosed is a method for forming calcium carbonate comprising the steps of providing a reaction medium; introducing carbon dioxide and the calcium hydroxide slurry simultaneously into a reaction medium to form calcium carbonate while maintaining constant pH during calcium carbonate precipitation; and optionally drying the calcium carbonate slurry to form a dried calcium carbonate product. A...
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COLLOIDAL MICROCRYSTALLINE CELLULOSE TOOTHPASTE OF REDUCED STRINGINESS AND IMPROVED FLAVOR RELEASE

(WO2004071322) 26.08.2004 A61K 8/73 FMC CORPORATION
A toothpaste composition with enhanced flavor release and reduced stringiness is disclosed. The composition comprises an abrasive, a humectant, a binder, a co-binder, a surface active agent, and water; in which: the co-binder is colloidal microcrystalline cellulose co-processed with a surfactant; colloidal microcrystalline cellulose co-processed with a hydrocolloid; colloidal microcrystalline cellulose co-processed with a hydrocolloid and an attriting agent; a mixture of colloidal microcrystalline cellulose co-processed with a hydrocolloid and an attriting agent in which the microcrystalline cellulose to attriting agent ratio is about 85:15 to about 30:70 by weight and the mean particle size of the attriting agent is about 0.1 to about 8 mi...
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TOOTHPASTE COMPOSITIONS WITH REDUCED ABRASIVITY

(WO2004071321) 26.08.2004 A61K 6/00 FMC CORPORATION
Toothpaste compositions are disclosed. The toothpaste composition comprises a binder; a surface active agent; an abrasive; a humectant; and water; in which: (1) the abrasive is silica, the composition additionally comprises a silica thickener, and the composition comprises 1 to 7 wt % of the silica thickener, less than 15 wt % of the silica abrasive, 45 to 70 wt % water, 0.8 to 3.0 wt % of a surface active agent; 0.05 to 3.0 wt % the binder; or (2) the abrasive is silica, the composition additionally comprises a silica thickener, the composition comprises 2 to 22 wt % total silica, 0.8 to 3.0 wt % of a surface active agent; 0.05 to 3.0 wt % the binder, and the composition additionally comprises about 0.1 to 8.0 wt % of non-colloidal microcr...
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DENTAL WHITENING COMPOSITIONS AND METHODS

(WO2004069215) 19.08.2004 A61K 8/21 3M INNOVATIVE PROPERTIES COMPANY
Dental whitening compositions including a polymer and a tooth whitening agent are provided. The dental whitening compositions, which optionally may be hardenable, are useful for coating oral surfaces.
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MULTIVALENT ION COMPATIBLE CARBOMER FORMULATIONS

(WO2004069170) 19.08.2004 A61K 8/73 NOVEON IP HOLDINGS CORP.
A polymeric formulation, and more specifically, a toothpaste formulation, is disclosed containing a highly carboxylated polymer or copolymer derived from one or more unsaturated carboxylic acids in combination with a calcium carbonate abrasive, a galactomannan, and traditional filler materials. The formulation is especially useful where sources of multivalent cations would otherwise cause phase separation and instability of the toothpaste.
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DENTAL ADHESIVE STRIP

(WO2004069077) 19.08.2004 A61C 5/04 CLEGG, Mary, L.
A flexible, transparent, dental adhesive strip (10) having a dental adhesive (12) uniformly coated onto one side of the strip for use during dental procedures. The strip is adhered to a tooth under repair to retain and shape a restorative material used to fill a void or cavity in the tooth. The strip may also be adhered to a tooth adjacent to a tooth under repair to provide protection against contact with materials used during the procedure on the tooth under repair.
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ORAL DEVICES AND METHODS FOR CONTROLLED DRUG DELIVERY

(WO2004069076) 19.08.2004 A61M 31/00 WOLFF, Andy
Controlled-drug-delivery oral devices are implanted or inserted into an oral cavity, built onto a prosthetic tooth crown, a denture plate, braces, a dental implant, or the like. The devices are refilled or replaced as needed. The controlled drug delivery may be passive, based on a dosage form, or electro-mechanically controlled, for a high-precision, intelligent, drug delivery. Additionally, the controlled delivery method may vary and depend on a variety of factors. Drug absorption in the oral cavity may be assisted or induced by a transport mechanism. The oral devices require refilling or replacement at relatively long intervals of weeks or months, maintain a desired dosage level in the oral cavity, hence in the gastrointestinal tract, for...
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A PROCESS OF PREPARING A HERBAL FILLER COMPOSITION FOR BIDI CIGARETTE AND THE LIKE

(WO2004068974) 19.08.2004 A24B 15/16 MURALI, Panchapagesa, Muthuswamy
The present invention relates to a process of preparing herbal filler composition for bidi, cigarette and the like comprising: shredding the shade dried leaves of Lawsonia inermis L. and Ocimum santum L. separately and mixing them the ratio 1:0.72-1 on weight / weight basis, tying the mixture with a sieve and placing it on the mouth of an pot containing the boiling sugar syrup, keeping said mixture for 20-30 minutes on said sieve, rotating said mixture continuously in the sieve, removing the mixture from the sieve and air drying the material, and cooling said mixture in shade.
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USE OF LACTIC ACID BACTERIA FOR REDUCING DENTAL CARIES AND BACTERIA CAUSING DENTAL CARIES

(WO2004067729) 12.08.2004 A61K 8/97 BIOGAIA AB
Strains of Lactobacillus that have been selected for their capability of reducing the number of Streptococcus mutans in the mouth of mammals through inhibiting activity in combination with good binding to the oral mucins and dental plaque, thereby preventing, reducing or treating dental caries, and products derived from said strains, including agents for treatment or prophylaxis of caries for administration to humans.
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OSTEOGENIC COMPOSITION

(WO2004067027) 12.08.2004 A61K 31/4015 THE UNIVERSITY OF ZURICH
The present invention relates to pharmaceutical composi-tions containing a synergistic amount of at least one bone morphogenetic protein (BMP) and a synergistic amount of at least one pyrrolidone optionally in a pharmaceutically acceptable carrier, such as a biodegradable polymer. The present invention further relates to methods of treating or-thopaedic and dental, including periodontal, diseases by simultaneously administering a synergistic amount of at least one bone morphogenetic protein (BMP) and a syner-gistic amount of at least one pyrrolidone optionally in a pharmaceutically acceptable carrier to patients in need of such treatment.
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PRE-SHAPED DENTAL TRAYS AND TREATMENT DEVICES AND METHODS THAT UTILIZE SUCH DENTAL TRAYS

(WO2004066858) 12.08.2004 A61C 5/00 ULTRADENT PRODUCTS, INC.
Pre-shaped, non-custom dental trays (100) are either preloaded with a dental treatment composition (112), such as a bleaching gel, or filled with the dental treatment composition just prior to placement over a person's teeth. The pre-shaped dental tray (100) is thin and flexible, which allows it to be placed over a person's teeth and then approximately conform to the person's teeth. The pre-shaped, non-custom dental trays (100) can therefore perform similarly to a customized tray but without having to go through a lengthy customization procedure. A pre-shaped dental tray can be pre-loaded with a dental treatment composition and stored within a sealed packaging container (450).
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TOOTHPASTE HOLDER AND DISPENSER

(WO2004066784) 12.08.2004 A47K 5/18 PIERRE-LOUIS, Jean
A toothpaste dispenser holds a collapsible tube of toothpaste within a housing between a roller assembly and a wall surface. A plunger is operable from a relaxed, raised position to a lowered, depressed position to drivingly engage the roller assembly so that one or more rollers are moved along the toothpaste tube in a manner which squeezes toothpaste out of the tube and onto the bristles of a toothbrush held in close proximity to a dispensing outlet of the tube or a nozzle. A spring returns the plunger to the relaxed, raised position upon removing the downward force. The housing is provided with toothbrush holders and a removable cover to permit replacement of the tube of toothpaste.
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BIOHAZARD MASK SUITABLE FOR CIVILIANS

(WO2004066764) 12.08.2004 A41D 1/00 BIOKIDZ USA
A biohazard mask for civilian use comprises bidirectional HEPA filtering to protect both personal and public health during an outbreak. Several measures are taken to maximize comfort and wearability, such as comfort-fit through a gel seal, anti-fogging protection through separation of the eye volume from the mouth-nose volume and through eye moisture release valves, heat-dissipation through a net suspension, and overpressure release valves to maintain the face seal during coughing or sneezing. Wicking exhalation filters promote moisture abatement around the mouth and nose. Attractive and stylish designs, combined with accommodation for telephone communication or audio entertainment, helps wearers keep the mask on during an outbreak.
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A COMPOSITION MATERIAL FOR TRANSMUCOSAL DELIVERY

(WO2004064811) 05.08.2004 A61K 9/00 MAGLE HOLDING AB
The invention refers to a composition material that is intended for rapid transmucosal delivery in the mouth of a biologically active substance when in contact with saliva. The composition material comprises at least one ionic carbohydrate, having at least one biologically active substance ionically bound thereto, and at least one wetable non-soluble polymeric carbohydrate. The invention also refers to a method of preparing the composition material, which comprises the steps of: (a) providing a mixture of the at least one biologically active substance and at least one ionic carbohydrate in a solvent having a permissive pH for ionic bonding of the at least one biologically active substance to the at least one ionic carbohydrate; (b) mixing t...
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DENTAL HYGIENE APPARATUS FOR SIMULTANEOUS CLEANING OF TEETH OF BOTH MAXILLARIES

(WO2004064666) 05.08.2004 A46B 9/04 JAME, Olivier
The invention concerns a dental hygiene apparatus for simultaneous cleaning of teeth of both maxillaries, comprising a block (1) designed to be inserted in the user's mouth and including two opposite surfaces in each of which is provided a groove (10, 11) designed to receive a dental arch of part thereof, said grooves (10, 11) being internally lined with brushes (14), while drive means enable the brushes (14) to be displaced relative to the teeth. The brushes (14) are fixedly mounted on said block (1), while the drive means consist in a drive assembly (2) linked to the block (1) and designed to be hand-held, and which, via transmission means (5), is adapted to drive the block (1) in a reciprocating movement to move the brushes (14) relative...
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DENTAL COMPOSITIONS INCLUDING ENZYMES AND METHODS

(WO2004060325) 22.07.2004 A61K 6/00 3M INNOVATIVE PROPERTIES COMPANY
A hardenable dental composition that includes a polymerizable component and a therapeutic enzyme mixed within the polymerizable component, wherein upon hardening the polymerizable component to form a hardened dental material having a therapeutic enzyme mixed therein, the hardened dental material with the enzyme mixed therein is in contact with saliva in a subject's mouth for at least 1 day.
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SUBTILISIN VARIANTS, WITH IMPROVED PERHYDROLASE ACTIVITY

(WO2004058961) 15.07.2004 C12N 9/56 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to novel perhydrolases, derived from the protease Carlsberg by amino acid exchange in positions 11, 15, 21, 38, 50, 54, 58, 77, 83, 89, 93, 96, 107, 117, 120, 134, 135, 136, 140, 147, 150, 154, 155, 160, 161, 171, 179, 180, 181, 194, 205, 208, 213, 216, 217, 238, 239, 251, 253, 257 and/or 261. The invention further relates to methods for production of said novel perhydrolases, means, in particular bodycare, haircare, shampoo, hair-dyeing, hair-bleaching, oral-care, dental-care, dental-prosthesis-care, cosmetic, therapeutic, (textile) washing, cleaning, rinsing, handwash, washing-up and dish-washing means, comprising said novel perhydrolases and corresponding applications of said novel perhydrolases.
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CHOLINE OXIDASES

(WO2004058955) 15.07.2004 A61K 8/66 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to choline oxidases, methods for obtaining the same, bodycare products, haircare products, shampoos, oral, dental and dental prosthesis care products, cosmetics, washing products, cleaning products, rinsing products, hand soaps, washing-up detergents and dishwasher detergents comprising novel choline oxidases and uses of the choline oxidases.
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WATER-SOLUBLE FILM FOR ORAL USE

(WO2004058217) 15.07.2004 A61K 8/02 MONOSOL LLC
Physiologically acceptable films, such as water-soluble films, are disclosed. The films include a water-soluble film-forming polymer such as methylhydroxypropylcellulose and/or sodium alginate. Edible films are disclosed that include methylhydroxypropylcellulose and/or sodium alginate, breath freshening agents, stabilizing agents, plasticizers, surfactants, disintegrants, and preservatives. The edible films may be used to deliver an effective amount of an agent for killing bacteria that causes such maladies as dental plaque, gingivitis, bad breath, or the like. The film may optionally contain pharmaceutically active agents.
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POLYORGANOSILOXANE DENTAL IMPRESSION MATERIAL

(WO2004058196) 15.07.2004 A61K 6/10 DENTSPLY INTEWRNATIONAL INC.
A dental impression material comprising a polyvinylsiloxane and a surfactant, wherein said surfactant imparts wettability to the composition, such that the material has a surface contact angle with water of less than about 10 degrees after about 15 seconds.
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INTRAORAL CALCULUS DISSOLVING GEL COMPOSITION

(WO2004058180) 15.07.2004 A61C 5/00 ARSENAULT, Peter
A dental composition in gel form is taught that is applied to a users teeth for a period of time using a dental tray. The gel utilizes the enzyme papaine to soften calculus on the teeth so that it may be removed by tooth brushing, flossing and rinsing.
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BACTERIOPHAGE-ENCODED ANTIBACTERIAL ENZYME FOR THE TREATMENT AND PREVENTION OF GINGIVITIS AND ROOT SURFACE CARIES

(WO2004058088) 15.07.2004 C12Q 1/34 UNIVERSITY OF MARYLAND, BALTIMORE
A method and composition for the treatment and prevention of gingivitis and root surface caries using Actinomyces naeslundii bacteriophage Av-1 encoded anti-bacterial enzyme (Av-1 lysin) to remove and inhibit establishment of cariogenic and pathogenic bacteria in the oral cavity is disclosed, along with the amino acid sequence of the enzyme used therein and the isolated DNA molecule encoding the same.
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METHODS AND COMPOSITIONS FOR WOUND MANAGEMENT

(WO2004056346) 08.07.2004 A61K 9/70 UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
The present invention provides methods for wound management that comprise contacting a wound of a patient with an effective amount of a therapeutic composition comprising a chelating agent, a pH buffering agent, an antimicrobial agent, Vitamin E and a carrier and a surfactant. The antimicrobial agent(s) has increased antimicrobial activity because of the synergy with the chelating agent and maintenance of the treated area at a pH suitable for sustained antibiotic activity so that the antimicrobial agent can be used in effective doses that are less than in the absence of the chelator. The Vitamin E promotes tissue repair, reducing the likelihood of opportunistic infection, improving wound healing and reducing pain sensation. The wound manage...
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COMPOUND DELIVERY SYSTEMS COMPRISING A COOLING COMPOUND SUCH AS MENTHOL OR ICILIN

(WO2004056332) 08.07.2004 A23L 1/226 UNILEVER PLC
A composition comprising(a) from 0.005% to 0.5% by weight of a cooling compound;(b) from 0.1% to 10% by weight of an emulsifiable substance;(c) from 0.15% to 15% by weight of a surfactant;(d) optionally up to 5% by weight, preferably from 0.05% to 5% by weight of a cosurfactant. The cooling compound is preferrably icilin or menthol. The composition is to be used in toothpestes, mouthwashes, bererages, water, ice, spreads, dressings or ice cream.
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DENTAL FORMULATION

(WO2004056325) 08.07.2004 A61K 6/083 NSI DENTAL PTY LIMITED
This invention relates to formulations for treating or reducing dentine hypersensitivity that causes pain arising from exposed dentine in the oral cavity. The present invention seeks to provide formulations for physical blockage of dentinal tubules that have long term effectiveness and cause minimal irritation (if any at all) to the tissues of the oral cavity. Preferred formulations should be easy to apply, be immediately effective and maintain dentinal tubule occlusion under normal teeth cleaning regimes that include regular tooth brushing. The invention provides a formulation for reducing dentine sensitivity in the oral cavity, which incorporates at least one physical desensitising agent in form of a light curable monomer that forms a res...
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PROTECTIVE CASE FOR DELICATE OBJECTS

(WO2004056231) 08.07.2004 A45C 11/00 BASTUS CORTES, Pedro
The invention relates to a protective case for delicate objects. The inventive case comprises a tubular body (1) which is formed by a circular knit fabric, an elastic strip (2) which is disposed at the mouth (3) which is defined at one of the ends of the aforementioned tubular body (1) and a fine seam (4) which permanently seals the opposite end of said tubular body (1).
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INHALATION DEVICE FOR TRANSPULMONARY ADMINISTRATION

(WO2004054647) 01.07.2004 A61M 15/00 OTSUKA PHARMACEUTICAL CO., LTD.
An inhalation device for transpulmonary administration comprises: a chamber (16) for containing a pharmaceutical composition which is pulverized into fine particles by an air-generated impact for dispersal in air; an air inlet flow path (2) for introducing to the chamber (16) outside air to apply the air-generated impact to the pharmaceutical composition and for injecting the outside air toward the pharmaceutical composition; an inhalation flow path (1) for inhaling the pulverized pharmaceutical composition; a housing (9) for accommodating the chamber (16), the air inlet flow path (2), and the inhalation flow path (1); a mouthpiece (10) provided at one end of the housing (9), the mouthpiece (9) being provided with a mouth-side flow path (11...
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STAINING AGENT IN TABLET FORM FOR MAKING VISIBLE THE FORMATION OF DENTAL PLAQUE AND METHOD FOR PRODUCING SUCH A TINTING AGENT

(WO2004054528) 01.07.2004 A61K 8/36 HAGER &WERKEN GMBH &CO. KG
The staining agent for making visible the formation of dental plaque is characterized in that it is available in tablet form and is composed as follows: lactose ranging from approximately 85 to 95 % by weight, phloxin B ranging from approximately 1.5 to 2.6 % by weight, FDA Blue No. 1 ranging from approximately 2.5 to 3.5 % by weight and magnesium stearate ranging from approximately 0.15 to 0.25 % by weight. The inventive staining agent can contain peppermint or eucalyptus flavors that are conventional in dental and oral hygiene products. These flavors range from approximately 0.3 to 0.75 % by weight and are used for their disinfecting and refreshing effect.
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TEMPORARY, PHARMACOLOGICALLY-INACTIVE DENTAL COATING FOR THE IN SITU PROTECTION OF DENTAL THERAPEUTIC AGENTS FROM SALIVA AND ABRASION FROM CHEWING

(WO2004054518) 01.07.2004 A61K 6/00 CHX TECHNOLOGIES, INC.
Topical application of a pharmacologically-inactive, inert polymeric solution to teeth affords a temporary, protective barrier for pharmacologically-active compounds that have been previously applied topically to the tooth surfaces for caries reduction. In a method of use, an aqueous dispersion polymethylmethacrylate (PMMA) and a suitable plasticizer are applied topically to the tooth surface immediately after the topical application of chlorhexidine or fluoride. The inert coating thus formed is distinct from any pharmacologically-active substance, and remains on the tooth surface until abraded by the chewing of hard foods. In a composition of matter, the solution contains ammonio methacrylate copolymer, type B USP/NF of between 20% and 35%...
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DENTAL CERAMIC MIXING PLATE

(WO2004054468) 01.07.2004 A61C 19/00 CHANG, Ki-Whan
Disclosed is a dental ceramic mixing plate capable of preparing and maintaining ceramic paste in the optimum condition, and helping a user to easily perform a build-up process when ceramic prosthesis is manufactured in a dental clinic or in a dental laboratory. The dental ceramic mixing plate includes: a body having a container, the container having recesses for containing water; ceramic boards seated in the recesses of the container respectively, each ceramic board having a number of vertical pore channels being continuously adjacent to each other; water-retention filter members, each of which is put on each ceramic board; and porous filter members, each of which is put on each water-retention filter member and has a number of fine pores a...
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METHODS OF USING A BEVERAGE COMPOSITION

(WO2004054390) 01.07.2004 A23L 2/52 THE PROCTER &GAMBLE COMPANY
The present invention is directed to a method of treating dental erosion, preventing dental discoloration or both comprising orally administering to a mammal (preferably, a human) a beverage composition having a pH of greater than about 5.5; wherein the beverage composition comprises a compound having the structure (I): wherein n is an integer averaging from about 7 to about 100 and M, M', and M'' are each, independently, selected from the group consisting of sodium and potassium. The present invention is further directed to kits comprising the foregoing beverage composition and information that use of the beverage composition provides treatment against dental erosion, dental discoloration or both.
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COMPOSITION FOR TOPICAL ANESTHESIA

(WO2004052399) 24.06.2004 A61K 31/138 SHOWA YAKUHIN KAKO CO., LTD.
A composition for topical anesthesia which contains a topical anesthetic agent such as lidocaine hydrochloride serving as the active ingredient together with an anesthetic effect-persisting agent selected from the group comprising antihistamine agents such as diphenhydramine hydrochloride and hydroxyzine hydrochloride and is substantially free from catecholamines such as epinephrine. This composition, the intensity and persistence of topical anesthesia of which are elevated without using catecholamines, is useful as a safe topical anesthetic agent for a dental operation within a short time such as tooth extraction and an oral surgery.
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METHOD AND APPARATUS FOR BLEACHING TEETH

(WO2004049966) 17.06.2004 A61C 19/06 WASYLUCHA, Bryan
A method and apparatus for whitening teeth which allow the user to undergo dental bleaching with the mouth closed and without protruding instruments, trays or electrical wires and the like. The apparatus includes a support structure and a dental whitening composition in contact with the support structure. A light source is included in the apparatus, disposed on or in the support structure so that light emitted from the source contacts on the dental whitening composition. The apparatus has a volume ranging between 0.5 - 450 cm 3 permitting the apparatus to fit entirely within the mouth of a user during treatment.
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DENTAL ADHESIVE COMPOSITION

(WO2004047773) 10.06.2004 A61K 6/00 SUN MEDICAL CO., LTD.
A dental adhesive composition characterized by comprising: a polyfunctional polymerizable monomer which is an ester having a structure made up of a C3-6 polyhydric alcohol moiety and two or more (meth)acrylic acid moieties and having one or two hydroxy groups; a monofunctional (meth)acrylate containing no hydroxy group in the molecule; a polymerizable monomer containing an acid group in the molecule; an organic boron compound as a hardener; and a filler. The dental adhesive composition can cure at an extremely high rate without exerting almost no influence on the bonding performance and working time of the composition and on the flexibility of the composition after curing.
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CASE FOR DENTAL CLEANING DEVICE AND CORRESPONDING DENTAL CLEANING DEVICE

(WO2004047669) 10.06.2004 A61C 15/04 GARCIA BOLUFER, Isabel
The invention relates to a case for a dental cleaning device and to the corresponding dental cleaning device. More specifically, the invention relates to a dental cleaning device comprising a support bearing a flavoured dental tape. The ends of said tape are connected to wide-open U-shaped arms. The inventive cleaning device, which is made from a flexible material, also comprises a handle-forming projecting element. The distance separating the aforementioned U-shaped arms enables the floss to be moved such as to rub the inner portion of the teeth. According to the invention, the surface of the tape floss is uneven, which facilitates the rubbing action. The dental cleaning device is disposed in a case having a lateral configuration correspon...
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APPETITE SUPPRESSANT TOOTHPASTE

(WO2004047661) 10.06.2004 A61K 8/92 ZUCKERMAN, Arthur
An appetite suppressant toothpaste formulations which simultaneously suppresses the users appetite while promoting intraoral cleanliness. The toothpaste composition includes toothpaste base ingredients; and at least one of appetite suppressant and appetite depressant herbs. The toothpaste base ingredients include a combination of known amounts of Vegetable Glycerin; Sorbitol, Hydrated Silica; Purified Water; Xylitol; Carrageenan; Sodium Lauryl Sulfate; and Titanium Dioxide and a flavoring agent. The appetite suppressing and depressing herbs include at least one of Garcinia Cambogia; Gymnema Sylvestre; Kola Nut; Citrus Aurantium; Yerba Mate; and Griffonia Simplicifolia and comprise a range of substantially 5.5 % to substantially 22 % by weig...
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CONFECTIONERY COMPOSITION

(WO2004047545) 10.06.2004 A23G 3/00 PHARES PHARMACEUTICAL RESEARCH N.V.
The invention provides a novel functional confectionery or confunctionery composition in a sealed pack, which may be stimulation sweets and in the form of solid compacts, or the like, preferably bilayered, for dissolution in the mouth for extended supply of energy and stimulant from external and endogenous sources, comprising (a) at least one sugar selected from the group consisting of mono, di and polysaccharides or preferably combinations thereof with trehalose, (b) at least one stimulant in a therapeutic amount or in combination with biologically active compound/ s, (c) a plurality of solid compacts, (d) each compact comprising a sub therapeutic unit dose of the said stimulant. Furthermore, there may be fewer undesirable properties norma...
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ARRANGEMENT AND METHOD FOR PERFORMING THE GRIPPING AND SEALING OF THE MOUTH OF HOLLOW OBJECTS FROM INSIDE THE MOUTH, IN CONNECTION WITH THE SEAL TESTING OF THE OBJECT

(WO2004046676) 03.06.2004 B29C 49/80 PIISPA, Kysti
The invention relates to an arrangement and method for gripping the mouth (5) of a hollow object on the inside of the mouth, and for sealing the mouth for seal testing. The arrangement comprises at least one gripping device, which includes a body part (1, 2) to which is connected a moving means (7) arranged to move with respect to the body part, around which moving means is arranged an intermediate piece to be inserted through the mouth of the hollow object, which comprises at least two gripping means (4). At the end of the moving means (7) is a spreading means (8) for spreading the gripping means (4) outwards, to provide a grip on the inside of the mouth of the hollow object. On the surface of the body part facing the mouth of the hollow o...
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ORAL PRODUCTS CONTAINING NOVEL FLAVOR COMPOSITION

(WO2004045590) 03.06.2004 A23G 3/00 WM. WRIGLEY JR. COMPANY
Oral products containing Erospicata oil and a cooling agent for a novel organoleptic experience and cost savings. The oral products of this invention include chewing gums, confections, mouthwashes, mouth sprays and edible thin film products.
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TOOTH BLEACHING PROCESS

(WO2004045538) 03.06.2004 A61K 8/22 DISCUS DENTAL, INC.
A system and method for tooth bleaching are disclosed wherein a patient's mouth is prepped for tooth bleaching treatment, a light activated tooth bleaching composition is applied on a tooth surface to be bleached, a lamp assembly is placed in position to activate the oxidizing compound in the bleaching composition, and one or more spacer is coupled to the patient and to the lamp assembly to set a distance between the two.
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CONTROLLED-DISSOLVING POLYMERIC DEVICE FOR THE ORAL CAVITY

(WO2004045446) 03.06.2004 A61C 19/06 SMITHKLINE BEECHAM CORPORATION
The invention is directed to a solid, controlled-dissolution composition for the oral cavity that adheres to hard dental surfaces, such as natural teeth and the surrounding soft tissue, and which creates a physical barrier to painful stimuli associated with dentinal hypersensivity.
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DENTAL LIGHT GUIDE

(WO2004045445) 03.06.2004 A61C 13/15 DEN-MAT CORPORATION
The present invention is a device that attaches to a light source to transmit and distribute light energy to the surface or internal chamber of a tooth for the purpose of photo-initiation of light curing resins and dental tooth whitening. More particularly, the invention may be used with a single or multiple Light Emitting Diode(s) to more efficiently collect and transmit the light energy emitted by the LED(s) resulting in increased total energy, uniform illumination, and collimation of the light energy delivered to the tooth.
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TEMPORARY DENTAL CEMENTS HAVING REDUCED TOOTH SENSITIVITY

(WO2004044085) 27.05.2004 A61K 6/00 ULTRADENT PRODUCTS, INC.
Temporary dental cements used to temporarily affix a dental prosthesis or appliance to a tooth or other dental substrate includes one or more soothing agent to prevent or reduce tooth sensitivity. The temporary dental cement includes a mixture of an ion leaching agent, polycarboxylic acid, a soothing agent and water. The soothing agent (e.g., 2-ethoxybenzoic acid and 2-methoxy-4-methylphenol) is added in an amount so as to reduce or eliminate tooth sensitivity associated with the reaction between the polycarboxylic and the ion leaching agent (base). The temporary cement composition is sufficiently hydrophilic that it can be readily removed from the tooth when it is desired to permanently restore the tooth.
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TOOTHPASTE COMPRISING AN INTEGRATED PLAQUE INDICATOR

(WO2004043418) 27.05.2004 A61K 8/22 WILKENS, Harald
Thoroughly cleaning teeth on a daily basis is indispensable for keeping human teeth healthy; however, plaque is generally not removed to a sufficient degree because it is not easy to see. Conventional plaque-dyeing agents allow plaque to be seen easily but are complicated to apply and leave traces of dyes. The inventive toothpaste comprises an integrated plaque indicator and allows plaque to be dyed only temporarily. The storage container for the toothpaste is provided with two separate chambers, one of which contains toothpaste mixed with a dyeing agent while the other one contains toothpaste mixed with a decolorizing agent. The two pastes blend when the quantity required for cleaning the teeth is dispensed. Even though the decolorizing pr...
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CHEWING GUM WITH ENCAPSULATED STAIN REMOVING AGENT

(WO2004043388) 27.05.2004 A61K 9/68 CADBURY, Adams USA LLC
A composition in the form of a chewing gum composition or a confectionery composition containing an encapsulated stain removing agent selected from anionic and non-ionic surfactants and methods of preparing and using the same to remove stains from dental material including teeth.
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SOLUBLE ORAL PATCH WITH COLLAGEN AND INTERLACED ACTIVE INGREDIENTS

(WO2004043351) 27.05.2004 A61K 9/00 HALEY, Jeffrey, T.
An adherent, soluble oral patch for delivering topical medication in the mouth including a hydrophilic polymer that is liquid at human mouth temperatures. Preferably, the hydrophilic polymer gels to a solid at temperatures just below human mouth temperatures, preferably collagen such as animal gelatin. The structure of the oral patch is formed with a porous network that remains solid at human mouth temperatures and slowly dissolves in saliva. In some embodiments, the network is elasto-plastic and in some cases it is hydrophilic. The hydrophilic polymer is located within pores of the network, along with a desired medication. The oral patch is formed by mixing and hydrating the ingredients, bringing them to above an activation temperature bel...
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DISPOSABLE MINI TOOTH BRUSH AND BRIGHTENER

(WO2004043203) 27.05.2004 A46B 11/00 VZQUEZ DE LA CUEVA, Jos, Manuel
The invention relates to a disposable mini tooth brush and brightener which is intended to maintain and promote an adequate dental hygiene level and to prevent the inconveniences associated with already-known means which are currently used for the same purpose. More specifically, the invention relates to a disposable mini tooth brush comprising toothpaste which is ready for use at any moment. The inventive brush can be easily transported by the user in a wallet, bag or any other location given the reduced dimensions and thickness thereof. According to the invention, the tooth brush comprises a laminar body in the form of a flat strip or band which is preferably made from a biodegradable material. The end section of one of the faces of the a...
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PULSATILE RELEASE COMPOSITIONS OF MILNACIPRAN

(WO2004039361) 13.05.2004 A61K 9/16 COLLEGIUM PHARMACEUTICAL, INC.
A once-a-day oral milnacipran pulsatile release composition has been developed that releases the drug in spaced apart 'pulses'. The dosage forms are comprised of first, second and optional third dosage units, with each dosage unit having a different drug release profile. This dosage form provides in vivo drug plasma levels characterized by Cmax below 3000 ng/ml, preferably below 2000 ng/ml, and most preferably below 1000 ng/ml. These levels help to avoid stimulation of the cholinergic effects on the CNS. The composition allows milnacipran to be delivered over approximately 24 hours, when administered to a patient in need, resulting in diminished incidence or decreased intensity of common milnacipran side effects such as sleep disturbance, n...
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ORAL ANTIMICROBIAL COMPOSITION AND USE THEREOF IN THE TREATMENT OF DENTAL PLAQUE AND GINGIVITIS

(WO2004039342) 13.05.2004 A61K 8/19 SEGURA LUDEA, Miguel Angel
The invention relates to an oral antimicrobial composition and to the use thereof in the treatment of dental plaque and gingivitis. The inventive composition is characterised in that it comprises: between 0.5 and 2 wt.- % active carbon as a surface active agent, between 2 and 3 wt.- % Carbopol 934 as a thickening agent, between 0.05 and 6 wt.- % flavouring agents and between 0.01 and 40 wt.- % sweetening agents.
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DENTAL CARE PRODUCT

(WO2004039282) 13.05.2004 A61C 15/00 YNDK PTY LTD
A masticating strip useful in dental hygiene consisting of a cellular foam in which the surface cells incorporate longitudinal slits. The strips are sized to give a chewing volume of 1 to 4 cm3 preferably about 3 cm3. The strips are made from a foam of a thermoplastic material selected from one or more of polyethylene (PE), polyvinyl acetate (PVA) or polyisobutylene. The strips may incorporate a dental adjuvant or a barrier material.
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COMPOSITIONS FOR REMOVING STAINS FROM DENTAL SURFACES

(WO2004039277) 13.05.2004 A23G 3/00 CADBURY ADAMS USA LLC
A composition for removing stains from dental surfaces comprising a stain removing effective amount of at least two active components selected from a peroxide compound, a polyphosphate, and an anionic surfactant, in combination with an orally acceptable carrier. The present invention is further directed to methods of making and using the same.
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BITE DEVICE USED WITH A PANORAMA X-RAY DEVICE

(WO2004039261) 13.05.2004 A61B 6/14 SIRONA DENTAL SYSTEMS GMBH
A bite device for the correct positioning of a patient when a panoramic x-ray is taken, comprising a holder part (42) which can be placed in a fixed direction in relation to the x-ray device, a plate (46) which can pivot against the holder and which is provided with a bite part (50) into which a patient bites, and means (58, 60) for detecting the pivoting angle A between the plate (46) and the holder part (42).
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FAT COMPOSITION FOR SPREAD

(WO2004039165) 13.05.2004 A23D 7/00 THE NISSHIN OILLIO GROUP, LTD.
A fat composition for spreads which has satisfactory meltability in the mouth, feels nonoily, and has satisfactory spreadability. The fat composition for spreads is one comprising a continuous fat phase and an aqueous phase and is characterized in that the fat phase comprises: (a) a liquid fat consisting mainly of triglycerides in which C8-10 fatty acids account for 10 wt.% or more of all the constituent fatty acids; (b) a low-melting fat obtained by subjecting 40 to 90 parts by weight of a palm fat and 60 to 10 parts by weight of a liquid fat to transesterification with the aid of 1,3-regioselective lipase; and (c) a solid fat having an increasing melting point of 38C or higher.
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FLUORINE-CONTAINING ZEOLITE GRANULE FOR USE IN TOOTHPASTES AND TOOTHPASTE COMPOSITION COMPRISING THE SAME

(WO2004037219) 06.05.2004 A61K 7/16 COSMO FINE CHEMICALS CO.,LTD
Disclosed is a zeolite granule for use in toothpaste and a toothpaste composition containing the same. The zeolite granule includes silica as an abrasive and fluorine as a strength enhancer at the same time. Further, the toothpaste composition has 0.5 to 40 wt% of the zeolite granule. Upon application of the zeolite granule to the toothpaste, the prepared toothpaste is advantageous in terms of superior protection efficacies against teeth cavities and high removal function of plaque and tartar form the teeth, and drastically increased storability. Moreover, in the current invention, there is required no a separate adding process of fluorine to provide resistance to tooth decay upon preparation of the toothpaste composition.
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DENTAL FILLING MATERIAL

(WO2004037214) 06.05.2004 A61K 6/083 PENTRON CLINICAL TECHNOLOGIES, LLC
A dental filling material comprising a thermoplastic polymer. The thermoplastic polymer may be biodegradable. A bioactive substance may also be included in the filling material. The thermoplastic polymer acts as a matrix for the bioactive substance. The composition may include other polymeric resins, fillers, plasticizers and other additives typically used in dental materials. The filling material is used for the filing of root canals.
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MODIFIED RELEASE COMPOSITIONS OF MILNACIPRAN

(WO2004037190) 06.05.2004 A61K 9/16 COLLEGIUM PHARMACEUTICAL, INC.
A once-a-day oral milnacipran modified release formulation has been developed. The formulation comprises an extended release dosage unit (Optionally containing the immediate release portion) coated with delayed release coating. The milnacipran composition, when administered orally, first passes through the stomach releasing from zero to less than 10% of the total milnacipran dose and then enters the intestines where drug is released slowly over an extended period of time. The release profile is characterized by a 0.05-4 hours lag time period during which less than 10% of the total milnacipran dose is released followed by a slow or extended release of the remaining drug over a defined period of time. The composition provides in vivo drug pla...
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ELECTRIC INTERDENTAL BRUSH

(WO2004037113) 06.05.2004 A61C 15/00 TAKAHASHI, Atsushi
Disclosed is an electric inter-dental brush device which is generally divided into a cleaning brush attached at a head assembly of the electric inter-dental brush device, a finger grip of a small size for holding a small-sized motor for driving the cleaning brush and a housing for holding a battery or AC adaptor for the small-sized motor and other components and parts of the electric inter-dental brush device. The finger grip and the housing are physically separated except through an electric cord connecting the small-sized motor and the battery or AC adaptor.
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TRAVEL MASK

(WO2004035141) 29.04.2004 A42B 3/22 HELP U SOLVE, INC.
A travel mask (10) that fits over the nose and mouth area of a wearer's face for filtration of air, particularly recycled air in the travel compartment of a common carrier, the travel mask having a face shield (16) that preferably includes an aroma patch (44) that emits a pleasant aroma and a retainer (18) such as a head band (20) for retaining the face shield against a user's head. The retainer has slidable ear plugs (40) for blocking noise. The travel mask also has a foldable eye flap or flaps (36) for blocking light when the flap or flaps are extended, the flap or flaps preferably having thermal gel packs (45) for cooling or warming the eye lid area of the wearer during use.
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MOUTH RINSE AND SPRAY NOZZLE FOR CREATING A LIQUID JET AND TEETH-CLEANING SYSTEM

(WO2004034923) 29.04.2004 A61C 1/00 BRAUN GMBH
The invention relates to a spray nozzle (1) creating a liquid jet for a mouth rinse. Said spray nozzle (1) comprises a nozzle member (2) that is provided with a chamber (6) into which extends a liquid duct (5) supplying pressurized cleaning liquid. A nozzle outlet (18, 19) which discharges a jet of cleaning liquid extends from said chamber (6). The chamber (6) is connected to a whirl chamber (15) that has an approximately round cross section and creates a circulating flow of the cleaning liquid. The nozzle outlet (18,19) extends centrally from the whirl chamber (15) and comprises an approximately cylindrical narrow passage and an adjacent especially approximately conical expansion. The cleaning liquid is delivered to the spray nozzle at hig...
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DENTAL FLOSS

(WO2004034922) 29.04.2004 D02G 3/34 JOHNSON &JOHNSON INDUSTRIAL LTDA
A dental floss that comprises at least one core yarn (10) and at least one effect yarn (20), which are formed by multiple filaments that are air jet textured and mutually interlaced, so as to form interdental insertion portions (I), which are separated from each other by cleaning portions (C) with a widened cross section. Each insertion portion (I) comprises substantially equal filament extensions of the core yarn (10) and of the effect yarn (20), whereas each cleaning portion (C) comprises filament extensions of the effect yarn (20) presenting a length that is substantially larger than the length of the filament extensions of the core yarn (10).
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DENTAL COATING KIT

(WO2004032884) 22.04.2004 A61K 6/00 KURARAY MEDICAL INC.
A dental coating kit realizing high adhesion to teeth, which includes a primer composition comprising a polymerizable monomer having acid group (a), water (b) and a water soluble solvent (c) and a surface lubricative composition comprising a polyfunctional polymerizable monomer (f), a volatile solvent (g) and a photopolymerization initiator (h); and a dental coating kit realizing high adhesion to teeth and appreciable resistance to chipping and fracture, which includes a primer composition comprising a polymerizable monomer having acid group (a), water (b) and a water soluble solvent (c), a coating composition comprising a polymerizable monomer (d) and a photopolymerization initiator (e) and a surface lubricative composition comprising a po...
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MUCOADHESIVE TETRACYCLINE FORMULATIONS

(WO2004032843) 22.04.2004 A61K 9/00 ORAPHARMA, INC.
Mucositis is treated and/or prevented by administrating to a patient a formulation containing a tetracycline and at least one cationic polymer and/or mucoadhesive material. The tetracycline may be in the form of a pharmaceutically acceptable salt or a base. The formulations may optionally also contain an antifungal agent to prevent fungal overgrowth due to reduction in the normal oral flora by the tetracycline. The formulation can be formed into liquid or solid dosage forms such as mouth rinse or tablet. Such compositions have the advantage of prolonged retention of the tetracycline in the mucosa of the oral cavity.
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CHEWING GUM FORMULATION AND METHOD OF MAKING THE SAME

(WO2004032644) 22.04.2004 A61K 9/68 SPI PHARMA, INC.
The present invention involves a novel chewing gum formulation and a method of making the same. The chewing gum formulation is used to form a final chewing gum composition which contains an active ingredient which is released from the chewing gum as the gum is masticated in the mouth of the user. The chewing gum made from the chewing gum composition of the present invention is initially a compressed body, such as a tablet, which quickly dissociates into a multiplicity of small pieces upon initial chewing followed by a reformation of the pieces into a coherent mass of chewing gum after a few seconds of chewing. Both the chewing gum formulation and the chewing gum composition are in the form of a free-flowing particulate which is capable of b...
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ILLUMINATOR ASSEMBLY

(WO2004032254) 15.04.2004 A61C 13/15 TELEDYNE LIGHTING AND DISPLAY PRODUCTS, INC.
An apparatus that includes a lens having a light entrance end forming a recess, a heat sink having an end portion facing the recess, and a light source positioned to transmit light via the recess into the lens. The light source is in thermal communication with the heat sink, which conducts away heat generated by the light source. The apparatus may be used to provide optical radiation at various wavelengths, activating tooth whitening material, and curing dental composite material.
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BLEACHING DEVICE EMPLOYING ELECTRO-OPTICAL AND CHEMICAL MEANS, WHICH IS INTENDED, IN PARTICULAR, FOR USE IN THE MEDICAL AND DENTAL FIELD

(WO2004028626) 08.04.2004 A61C 19/06 DURET, Franois
The invention relates to a bleaching device employing eletro-optical and chemical means, which is intended, in particular, for use in the medical and dental field in order to brighten parts of the body such as teeth, hairs and nails. The inventive device comprises: a variable-modulation and/or -profile electric, electrophoretic or electromagnetic wave current generator/controller (4); means (3) of transmitting said current towards the parts to be brightened; means of creating a non-traumatic electric, electrophoretic or electromagnetic field (2) through the treated zone, comprising electrodes and an electrode gel; means (1) of retaining said gel in contact with the poles and the body, thereby enabling field continuity; active bleaching prod...
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DENTAL COMPOSITIONS AND METHODS

(WO2004028498) 08.04.2004 A61K 8/22 THE BOOTS COMPANY PLC
A dental composition comprises a fluorescent whitening agent. The fluorescent whitening agent is most preferably 4,4'-bis(2-sulfostyryl)biphenyl or a salt or other soluble derivative thereof, eg the disodium salt. The composition may also comprise an additional tooth whitening agent. Methods of whitening the teeth are also described.
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BITE TRAY OF DENTAL

(WO2004028395) 08.04.2004 A61C 9/00 YE, Dong-Hae
Disclosed is a dental bite tray (1) comprising a knob (101) at its one side, a main frame (10) with a plurality of holes (100) connected to the knob (101), a sub frame (10) connected to the main frame (10) via a connector (102), and guide grooves (11) horizontally formed through the frames (10 and 10) for fixing a net (2) supporting a material (4) for patterning after a tooth. Fasteners (3) are individually attached to both ends of the net (2), insertion grooves (12) are individually formed in the guide grooves (11) so that the net (2) is inserted from the outside into the guide grooves (11) via the insertion grooves (12), thereby inserting both ends of the net (2) to the guide grooves (11) via the insertion grooves (12) and f...
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MOUTHPIECE DEVICES AND METHODS TO ALLOW UV WHITENING OF TEETH

(WO2004028393) 08.04.2004 A61C 1/08 TWILIGHT TEETH, INC.
A plastic mouthpiece insert for allowing a wearer to whiten their teeth while getting a suntan, and have a generally oblong ovalrectangular opening with a curved rear end that abuts against the root surfaces of the frontal upper and lower teeth of the wearer. A raised front edge can protect the lips and separate in place about the opening to the mouthpiece. Whitening agents can be used to enhance the whitening effect so that ultraviolet light and heat source such as the sun or a sunlamp is all that it is needed. Reflective inner walls in the mouthpiece can magnify light to the teeth. The mouthpiece can include bite tables, and the side walls of the mouthpiece can be inwardly flared and funnel shaped for focusing and magnifying incoming ligh...
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TOOTHBRUSH

(WO2004028235) 08.04.2004 A46B 9/04 COLGATE-PALMOLIVE COMPANY
A toothbrush (10) includes a head (14) having a prophylaxis polishing cup (16) closely surrounded by cleaning elements in the form of a bristle ring (18) extending above the upper surface (20) of the cup. Alternatively, the cups could be in the form of arrays of densely packed cleaning elements (116). The area formed by these configurations retains toothpaste on the toothbrush during use. Additional cleaning elements (124) may be arranged about the periphery of the toothbrush head. The toothbrush may be a powered toothbrush (110A) wherein the cups and/or bristle rings rotate, oscillate or reciprocate to better clean teeth.
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TREATMENT OF PERIODONTAL DISEASE WITH PHOTOSENSITIZERS

(WO2004024080) 25.03.2004 A61N 5/06 CERAMOPTEC INDUSTRIES, INC.
A method and composition is disclosed for treating oral diseases, including inflammatory periodontal disease, by utilizing photosensitizing compounds in long term effect or timed release formulations, including local highly concentrated formulations in biofilms on teeth and implants and oral wounds as well as periodontal pockets, and activating the photosensitizers with radiation to selectively destroy bacteria and other microbial bodies. Photosensitizers in a timed release formulation are released over a prolonged period of time. In a version, photosensitizers are housed within nanoparticles, and can be gradually released through biodegradation or periodically released by such processes as brushing, irradiation and chemically induced relea...
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DISPOSABLE PHOTOGRAPHIC CHEEK RETRACTION APPARATUS AND METHOD OF USING THE SAME

(WO2004024017) 25.03.2004 A61C 5/14 MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE INC
In an exemplary embodiment in accordance with the present invention, a disposable dental appliance and method of use is provided. In particular, a cheek retraction apparatus is provided, which is formed from a lightweight yet durable biocompatible polymer. The apparatus is sufficiently durable to withstand recurrent use, however, the it is economically manufactured so as to be disposable. Moreover, the apparatus is pre-sterilized to alleviate the need for autoclaving and/or dry heat sterilization. A cheek retraction apparatus in accordance with the present invention also provides an indicia display medium that allows the dental practitioner to display patient information, whitening treatment measurements, or other indicia that might be usef...
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COMPOSITION FOR REINFORCING APATITE-BASED MATERIALS

(WO2004021970) 18.03.2004 A61L 27/12 DENTSPLY INTERNATIONAL INC.
The invention concerns a composition comprising at least one titanium and fluorine derivative for reinforcing materials based on natural or synthetic apatite, in particular teeth, bones, dental implants and surgical prostheses. The inventive compositions enable in particular apatite materials to be enriched with titanium and fluorine. The invention also concerns a method for reinforcing apatite-based materials using said compositions, and use of titanium and fluorine derivatives to fight against staining of apatite-based material.
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DISPOSABLE TOOTHBRUSH

(WO2004021914) 18.03.2004 A46B 11/00 COLGATE-PALMOLIVE COMPANY
A waterless, disposable toothbrush (10) is disclosed and includes a handle (14) having a toothpick (16) connected thereto to enable cleaning between teeth, and a rupturable dispenser (32) containing a dentifrice and being connected in a bristle portion of the toothbrush head (12) for dispensing the dentifrice to the teeth to provide teeth cleaning and breath freshening, all of which deliver a cleaning, polishing, whitening, between teeth cleaning, and beath freshening action. The disposable toothbrush (10) of the present invention combines three benefits into one disposable toothbrush: (1) tooth surface cleaning with the toothbrush bristles and the dentifrice in the rupturable dispenser; (2) between teeth cleaning with the toothpick; and (3...
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DUAL COMPONENT DENTAL COMPOSITION CONTAINING ENZYME

(WO2004019899) 11.03.2004 A61K 8/66 COLGATE-PALMOLIVE COMPANY
A two component desensitizing dentifrice composition is disclosed which comprises a first dentifrice component containing an enzyme such as papain and a second dentifrice component containing an ionic surfactant such as sodium lauryl sulfate, the first and second dentifrice components being maintained separate from the other until dispensed for application to teeth whereby enzyme activity is maintained with improved dentifrice foaming characteristics.
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METHOD FOR REMOVING A DENTAL CROWN AND APPARATUS THEREFOR

(WO2004019805) 11.03.2004 A61C 1/07 DENTSPLY INTERNATIONAL INC.
Method and tool for fracturing the cement interface between a crown and a tooth or the like. The method is accomplished by positioning a piezoelectric driven rapid impacting tool against one side of a portion of a crown covering the tooth. The tool is covered with a malleable metal and is interfacing abutment with said crown. The opposite side of the crown is abutted against an anvil which is covered with a thicker malleable metal interface.
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COMBINATION OF ROTATING DENTAL CLEANING BRUSH AND PASTE DESPENSER

(WO2004017859) 04.03.2004 A61C 17/00 TARR, Daniel, Edward
The invention relates to the combination of rotating dental cleaning brush and paste device as well as the method for using such a device. The device includes a housing having a rotating shaft passing therethrough. An accordion tube has two opposed ends, a first end connected to and rotated by the shaft and a second end. A flexible conical brush is connected to and rotated by the second end of the accordion tube. Dental paste is pre-loaded and stored inside of the accordion tube whereby axial compression of the accordion tube forces the dental paste out of the second end of the accordion tube and on to the brush.
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STABLE, LOW FREE FORMALDEHYDE, SYNERGISTIC ANTIMICROBIAL COMPOSITIONS OF ALDEHYDE DONORS AND DEHYDROACETIC ACID

(WO2004017736) 04.03.2004 A01N 43/50 LONZA, INC.
The present invention provides a stable, low free formaldehyde, synergistic antimicrobial composition, and a method of inhibiting the growth of or reducing microorganisms by applying the composition. Preferably, the constituents are dimethylol dimethylhydantoin, monomethylol dimethylhydantoin, dimethyl hydantoin, and dehydroacetic acid or its salts thereof. The composition has a free formaldehyde content of less than 0.2% and is beneficial for controlling microbiological and fungal contamination in personal care products, household products and industrial products and systems.
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PHARMACEUTICAL COMPOSITIONS FOR BUCCAL DELIVERY OF PAIN RELIEF MEDICATIONS

(WO2004016244) 26.02.2004 A61K 9/00 GENEREX PHARMACEUTICALS INC.
Pharmaceutical compositions comprising a narcotic analgesic in mixed micellar form are disclosed. The mixed micelles are formed from an alkali metal alkyl sulfate, and other micelle-forming compounds as described in the specification. Micelle size ranges between about 1 and 10 nanometers. Methods for making and using the compositions are also disclosed. A preferred method for administering the present composition is through the buccal mucosa of the mouth.
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METHODS OF ADMINISTERING AND ENHANCING ABSORPTION OF PHARMACEUTICAL AGENTS

(WO2004016243) 26.02.2004 A61K 31/4468 GENEREX PHARMACEUTICALS INC.
Pharmaceutical compositions comprising a macromolecular pharmaceutical agent in mixed micellar form are disclosed. The mixed micelles are formed from an alkali metal alkyl sulfate, and at least three different micelle-forming compounds as described in the specification. Micelle size ranges between about l and 10 nanometers. Methods for administering the compositions are also disclosed. A preferred method for administering the present composition is through the buccal region of the mouth, which has been demonstrated to achieve peak plasma levels of the pharmaceutical agent in about thirty minutes.
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A METHOD OF WHITENING TEETH

(WO2004016237) 26.02.2004 A61K 8/22 THE PROCTER &GAMBLE COMPANY
The present invention provides a method of whitening a person's teeth comprising treating the teeth with a whitening dentifrice and subsequently, but within a ten minute period thereafter, applying a self-supporting film of liquid bleaching product to said teeth, for a bleaching period of at least five minutes, preferably overnight. At the end of the bleaching period the whitening dentifrice can be used to remove residual bleaching product and the whole process repeated. The whitening dentifrice comprises a surface stain remover, selected from water-soluble polyphosphates, phosphonate polymers and dental abrasives having an RDA value greater than 120, which enhances the whitening effect. The bleaching product comprises a tooth bleaching age...
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MULTIFUNCTIONAL FLAVOR SYSTEMS AND METHOD OF USE

(WO2004014348) 19.02.2004 A23G 4/00 GURIN, Michael
A composition and method for functionalizing confectionery, chewing gum, oral care and beverage products by intensifying the flavor using ingredients comprised of flavor potentiators, enhancers, and amplifiers. The composition is further comprised of oral care actives selected to control halitosis and dental plaque utilizing polyphenols and enzymes whose activity levels are protected by stabilization methods. Such stabilization methods enhance and prolong the flavor release characteristics of such products.
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ARRANGEMENT RELATED TO A DENTAL SENSOR

(WO2004013691) 12.02.2004 A61B 6/14 JAN E WESTERLUND AB
The present invention pertains to an arrangement relating to a sensor plate for dental X-raying or photographic purposes, wherein the plate (10;10;10;10) for example is of a digital or analogue type and is intended for one-time use or for many-times use. The sensor plate (10;10;10;10) includes or carries elements (30,31;30,31;61-64;80-82;90;95) that are intended for engagement with a plate holding element (40) in a number of different positions (A-F). The holding element (40) includes means (51,52;50) for engagement with engagement elements (30,31;30,31;61-64;80-82;90;95) of the sensor plate.
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USE OF LACTOBACILLUS TO PRODUCE EXOPOLYSACCHARIDES IN FOOD AND PHARMACEUTICAL COMPOSITIONS

(WO2004013343) 12.02.2004 A23L 1/03 DANISCO A/S
The present invention relates to a composition and a method of preparing or treating food products so as to improve their aroma, flavour, mildness, sweetness, consistency, texture, body, mouth feel, firmness, viscosity, gel fracture, wheying off, structure and/or organoleptic properties, nutrition and/or health benefits. In particular, the present invention provides a composition comprising a live micro-organism, an enzyme produced by said micro-organism and an exopolysaccharide (EPS) produced by the activity of said enzyme.
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DENTINAL DESENSITIZING DENTIFRICE

(WO2004012693) 12.02.2004 A61K 8/19 COLGATE-PALMOLIVE COMPANY
A dental composition which eliminates or substantially reduces the discomfort and pain associated with dentinal hypersensitivity and exhibits enhanced anticaries and remineralization benefits which composition contains a fluoride ion and a potassium ion releasable salt and has a pH in the range of about 8 to about 9.9, the pH being buffered with phosphate salt.
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ORTHODONTIC FLOSSING GUIDE

(WO2004012624) 12.02.2004 A61C 15/04 STALLINGS, Joann, Marie
The invention provides a flossing device to remove debris, food, plaque, and bacteria from in between the proximal surfaces of teeth undergoing orthodontic treatment. In an embodiment of the invention, a dental flossing guide (100) comprises a lead portion (105) and floss filament (110) attached thereto and extending therefrom. The lead portion (105) comprises two wires (120, 130) mechanically entwined with the floss filament and a soft flexible coating (140), with a good portion of the floss filament extending long enough to be grabbed by two hands. The flossing guide features a small diameter to fit between the orthodontic wire and the front portion of the tooth. The soft coating and a curvilinear tip of the flossing guide protects the gi...
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DENTAL IMPLEMENT AND METHOD FOR TOOTH SURFACE INSPECTION

(WO2004012593) 12.02.2004 A61B 1/247 INSPEKTOR RESEARCH SYSTEMS B.V.
Described are dental implements useful for inspecting tooth surfaces for abnormalities such as caries or plaque. Preferred implements of the invention include light-emitting diodes mounted on an implement body having a mirror for insertion into a user's mouth. Such implements also have on-board batteries mounted in chambers in the implement handle, and a switch for energizing and de-energizing the LED with the battery. Also described are methods for examining tooth surfaces for abnormal conditions indicative of plaque involving illuminating surfaces with radiation at a wavelength in the range of 390-450 nm wherein the radiation is effective to cause detectable fluorescence emissions from bacterial metabolites known to be associated with pla...
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BONE REPAIR PUTTY COMPRISING POROUS PARTICULATE AND CARRIER GEL

(WO2004011053) 05.02.2004 A61L 24/00 DENTSPLY INTERNATIONAL INC.
A bone repair material is described that is of putty-like consistency, particularly useful for repairing dental bony defects such as those caused by bone loss resulting from moderate or severe periodontitis, augmenting of bony defects of the alveolar ridge, filling tooth extraction sites, or sinus elevation grafting. The repair material includes a porous, resorbable particulate that is bone-derived or derived from bone-like hydroxyapatite or synthetic hydroxyapatite; and, a resorbable carrier, such as high molecular weight polysaccharides, such as hyaluronic acid. A high concentration of particulate in the putty enhances bone repair and requires a high concentration of carrier to retain the putty at the defect site. For a particulate densit...
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CARDIOVASCULAR HEALTH ENHANCEMENT WITH SOY FORTIFIED ORANGE JUICE COMPOSITIONS

(WO2004011016) 05.02.2004 A23L 2/06 TROPICANA PRODUCTS, INC.
A method is provided for administering to an individual a soy fortified orange juice composition which includes soy protein that readily dissolves in orange juice and does not unacceptably negatively impact sensory, mouth feel and viscosity attributes of the orange juice component. When administering daily, these compositions enhance cardiovascular health indicators include cholesterol levels and blood pressure readings for the individual so treated.
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USE OF A COMPOSITION COMPRISING ORANGE JUICE FOR MODIFYING THE LEVEL OF CHOLESTEROL IN AN INDIVIDUAL

(WO2004011015) 05.02.2004 A23L 2/06 TROPICANA PRODUCTS, INC.
A method is provided for administering to an individual a soy fortified citrus juice composition which includes soy protein that readily dissolves in citrus juice and does not unacceptably negatively impact sensory, mouth feel and viscosity attributes of the citrus juice component. When administered daily, these compositions enhance cardiovascular health indicators in the individual. The cardiovascular health indicators include cholesterol levels and blood pressure readings for the individual so treated.
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ORAL AND DENTAL COMPOSITION

(WO2004011011) 05.02.2004 A61K 31/4425 SHANAHAN, Patrick, John
The invention provides an oral and dental composition comprising an effective antibacterial amount of a combination of: a) a physiologically acceptable divalent metal ion; b) a quaternary ammonium compound; and c) chitosan or a chitosan derivative in a form to facilitate interaction with the other two components of the combination; and a physiologically acceptable excipient.
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DUAL COMPONENT BIS-BIGUANIDE CONTAINING DENTIFRICE OF IMPROVED STABILITY

(WO2004010963) 05.02.2004 A61K 8/21 COLGATE-PALMOLIVE COMPANY
A dual component chlorhexidine dentifrice composition of improved shelf stability in which the first component is a gel containing a bis-biguanide antibacterial agent in which the gel vehicle is thickened with a cellulose polymer and the second component is a paste containing a silica abrasive wherein the bis-biguanide antibacterial agent provides undiminished antiplaque and antigingivitis effect with reduced staining when the physically separated components are combined and mixed upon application to dental tissue.
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LIQUID COMPOSITION FOR PROTECTING ORAL CAVITIES AND TEETH OF PET ANIMALS AND USE THEREOF IN PLAYTHING FOR PET ANIMALS

(WO2004010962) 05.02.2004 A61K 8/34 KOO, Bon-Gil
Disclosed are a liquid composition for protecting oral cavities and teeth of pet animals and the use thereof in playthings for pet animals. The liquid composition comprises xylitol in the amount of 10-50 weight parts; chitosan in the amount of 0.05-20 weight parts; an auxiliary component in the amount of 0.001-6 weight parts, selected from the group consisting of vitamin B2, vitamin B6, vitamin D3, allantoin, calcium gluconate, amino acids, collagen, and combinations thereof; and water in the balance to 100 weight parts, and ranges in viscosity from 700 to 4,000 cps and in pH from 5.5 to 7. The composition can clean the oral cavities of pet animals thanks to its antibacterial activity. When it is applied to a plaything, the composition is e...
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ORAL HUMECTANTS

(WO2004010961) 05.02.2004 A61K 6/00 HINO, Yasuo
An oral humectant and an oral humectant for dentures which can maintain humectation in the mouth and denture stability to thereby mitigate the symptom of oral xerosis and which comprises a safe polymer composition easy to use. The oral humectants comprise a polymer composition comprising a pharmaceutically acceptable water-soluble polymer, a pharmaceutically acceptable polyhydric alcohol, and water and/or an artificial saliva.
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AEROSOLIZED CERAMIC PORCELAINS AND GLAZE COMPOSITION

(WO2004009503) 29.01.2004 A61K 6/06 ENAMELITE, LLC
A spray glaze or opaque composition for coating dental restorations and other surfaces and objects such as hobby ceramics that comprises about 4 to about 50 weight % glaze material, about 5 to about 60 weight % restoration wetting agent, and about 10 to about 90% non CFC propellant. An opaque composition further comprises about 5 to about 30% opaque material.
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ORAL DELIVERY SYSTEM CONTAINING A GEL MATRIX AND LIPOSOMES

(WO2004009053) 29.01.2004 A23L 1/00 VITALSTATE CANADA LTD.
A transmucosal delivery system for oral delivery of one or more biologically active agent associated with an artificial membrane vesicle (AMV), such as a liposome, is provided. The system is especially suited for the delivery of biologically active agents with poor solubility, that are easily degraded in the gastrointestinal tract or that tend to have an unpleasant taste and mouth feel. The delivery system comprises a two-phase system whereby one or more AMV-associated biologically active agents are substantially uniformly dispersed in a semi-solid matrix that allows for maintenance of bioactivity. The dual phase system may further comprise one or more non-AMV associated biologically active agents incorporated within the matrix. Methods of ...
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SEALABLE BAGS AND METHOD OF MANUFACTURING

(WO2004007307) 22.01.2004 B31B 19/90 TAYLOR, Peter
A bag (10) is disclosed and comprises first (19) and second (13) walls connected together along their sides and bottom and a flap (24) connected to a top of one (13) of the walls. The flap (24) and this one wall (13) together form a transversely extending Z-fold. An adhesive strip (18) closes an open mouth (16) of the bag (10) and extends transversely across an inner surface of said one wall (13). A protective band (22) extends transversely across an inner section (64) of the flap (24) to cover and contact the strip. The flap (24) also has a projecting outer section (38) which can be pulled outwardly away from the interior of the bag to expose the strip. A method of making sheeting suitable for making these bags is also disclosed wherein an...
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ANTIBACTERIAL FORMULATIONS

(WO2004004650) 15.01.2004 A61K 8/31 WILKINS, Joe, S., Jr.
Novel toothpaste and mouthwash formulations as well as topical formulations are described herein. The formulations comprise therapeutically effective amounts of d-limonene for inhibiting the growth of or eradicating disease-causing pathogens. F.
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SOFT BETWEEN-TEETH CLEANER

(WO2004004515) 15.01.2004 A46B 9/04 TAKAHASHI, Atsushi
When inserting a between-teeth cleaner into between teeth using a mouth cavity-cleaner assistant tool, the tool can insert the cleaner between teeth while preventing gums from being hurt by the cleaner, and the cleaner can be inserted without giving pain or unpleasant feeling to the user. The cleaner fits without resistance between teeth with a limited insertion direction. There is no tooth root recess left unbrushed, and the tool is less likely to be broken during cleaning between teeth. The between-teeth cleaner has a between-teeth cleaning sponge connected to a movement shaft of an electric between-teeth cleaner or to a holding section of a manual between-teeth cleaner. The cleaner sponge is structured such that sponge (continuous porous...
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PROCESSES FOR FORMING DENTAL MATERIALS AND DEVICE

(WO2004002361) 08.01.2004 A61C 13/15 3M INNOVATIVE PROPERTIES COMPANY
Processes for forming dental materials that include applying a first hardenable dental composition (e.g., a dental adhesive) to a surface followed by applying a second hardenable dental composition (e.g., a dental composite) to the first hardenable dental composition on the surface. The first and second hardenable dental compositions are hardened such that the second hardenable composition is substantially completely hardened prior to complete hardening of the first hardenable composition.
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LIQUID CONTAINER, CAP STRUCTURE USED THEREFOR, AND CAP COVER

(WO2003000676) 31.12.2003 B65D 1/02 THE NISSHIN OILLIO, LTD.
A cleaning liquid bottle (1) comprising a bottle main body (2) having a mouth (3) and receiving a liquid, a cap (4) for sealing the mouth (3) of the bottle main body, and a cap over (5) removably mounted in the vicinity of the mouth (3) of the bottle main body (2), wherein the cap (4) comprises a cap main body (7) integrally attached to the periphery of the mouth (3) of the bottle main body (2) and having a first opening (19), a barrel (8) breakably integrally connected to the first opening (19) in the cap main body and having, on its top, a second opening (20) smaller than the first opening (19) in the cap main body (7), and a top (9) breakably integrally connected to the second opening (20) in the barrel, the cap cover (5) has, integrally...
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SYNTHETIC RESIN BOTTLE

(WO2003000674) 31.12.2003 B65D 1/02 HOKKAI CAN CO.,LTD.
A synthetic resin bottle having superior sealability between the mouth and the plastic cap. It has a thermally crystallized mouth (2) formed with a male thread (3). It also has a top plate (7), a cylindrical portion (8) having a female thread (9), a side seal (10), a cap liner (11), and a plastic cap (6) to be threadedly fitted on the mouth (2). The mouth (2) has a top plate abutment (15) abutting against the top plate (7) through the cap liner (11), and a side seal abutment (16) abutting against the side seal (10) through the cap liner (11). The side seal abutment (16) has an annular projection (17), the latter having a substantially semicircular cross-sectional contour, connecting to the top plate abutment (15) through a curved surface (1...
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STABLE COMPOSITIONS OF WATER SENSITIVE INGREDIENTS

(WO2003000282) 31.12.2003 A61K 9/00 CTS CHEMICAL INDUSTRIES LTD.
The present invention discloses a mouth-melt pharmaceutical composition that includes water-sensitive ingredient embedded in a hydrophobic fatty matrix having a melting point of between 30 and 40C. The water sensitive ingredient may be an active or a non-active ingredient of the composition. A pharmaceutical composition as disclosed, have the double benefit of having long shelf-life (despite of the water-sensitivity of one of its ingredients) and being easy to swallow. Thus, it may be used for administrating water-sensitive active ingredients to elderly subjects, or to any other population that has difficulty in swallowing hard tablets. On the other hand, it may be useful for administrating any kind of pharmaceutical composition with a...
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IMPROVED PHARMACEUTICAL DENTAL FORMULATIONS

(WO2003000253) 31.12.2003 A61K 9/00 J.B. CHEMICALS &PHARMACEUTICALS LTD.
An improved Pharmaceutical dental gel preparation comprising of metronidazole benzoate, chlorhexidine gluconate, and local anesthetic as the active ingredient; glycol as the solvent medium; a carboxyvinyl polymer as gelling polymer and a copolymer of methyl vinyl ether and maleic anhydride as mucoadhesive agent.
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THE USE OF BACTERIAL PHAGE ASSOCIATED LYSING PROTEINS FOR TREATING BACTERIAL DENTAL CARIES

(WO2003000222) 31.12.2003 A23G 3/00 NEW HORIZONS DIAGNOSTICS CORPORATION
A composition and method for treating bacterial dental caries by the use of an effective amount of at least one lytic specific for the bacteria causing dental caries. The lytic enzyme is genetically coded for by a bacteriophage which may be specific for said bacteria. The enzyme may be at least one lytic protein or peptides in a natural or modified form.
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QUICK DISSOLVE COMPOSITIONS AND TABLETS BASED THEREON

(WO2003000197) 31.12.2003 A61K 9/00 BIOVAIL LABORATORIES INC.
The invention provides a composition useful for making oral dosage forms capable of dissolving un the mouth in less than 40 seconds without the need for a conventional super disintegrant and having a friability of less than 1%, wherein the composition includes liquiflash particles and an excipient mass. according to the invention contains a directly compressible inorganic salt; a cellulose derivative or a combination of directly compressible inorganic salt and a cellulose derivative. Preferably,, the liquiflash particles and the excipient mass are combined in porportions such that the active ingredient remains substantially within the microspheres when the composition is compressed to obtain a dosage form having a hardness of 20 to 50 N. Th...
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USE OF A COMPOSITION AND A CLEANING TABLET CONTAINING SAID COMPOSITION FOR DISINFECTING PURPOSES

(WO2003000025) 31.12.2003 A01N 59/00 BONYF AG
The invention relates to the use of a composition containing: - at least one organic or inorganic compound or combination of substances, which separates chlorine or bromine in an aqueous solution; and - optionally, a surfactant (tenside) or surface-active mixture of substances, aromatic substances, auxiliary agents, and binding agents. Said composition is used for disinfecting dental objects such as toothbrushes and dentures as well as shaving devices, which are infected with retroviruses, herpes viruses, pseudomonas aeruginosa, and/or candida, and body parts that are infected with retroviruses or herpes viruses, pseudomonas aeruginosa, and/or candida.
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REDUCING FACIAL AGEING AND APPLIANCE THEREFOR

(WO2003105716) 24.12.2003 A61C 7/08 MOHINDRA, Naresh, Kumar
A mass produced universal dental appliance (1) comprises two parts, the parts intended in use to contact the posterior teeth on respective opposite sides of either the upper or lower jaw, each part comprising a composite structure comprising: iii) a first layer (2) formed a durable, resilient, elastomeric material having a softening point in the range from 35 to 100C and which in use contacts and grips the occlusal biting surfaces of the posterior teeth; and iv) a second layer (3) formed from a durable, non-deformable material having a softening point over 100C and which in use provides a bite plate; wherein the second layer of each part is provided with a protrusion (5), formed of durable, non-deformable material having a softeni...
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DENTAL WHITENING

(WO2003105715) 24.12.2003 A61C 19/06 DEN-MAT CORPORATION
Teeth whitening is disclosed using a wand applicator (10) that may apply a whitening composition directly to the one or more teeth to be whitened. The teeth whitening may include capping a whitening composition container (50) with a wand applicator. Kits and whitening compositions for the same are also disclosed.
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INTERPROXIMAL BRUSH WITH GARGLE AND DISINFECTANT

(WO2003105711) 24.12.2003 A45D 34/04 HAN, Sang-kee
Disclosed herein is an interproximal brush with gargle (7) and disinfectant (60). This interproximal brush includes two brush units. The brush units (200, 300) each include a handle (3) having a rectangular cross-section, and an interproximal cleaning means (2), such as bristles (5, 20b, 50b) or dental floss, fixed to an end of the handle (3). The interproximal brush also has a casing (1, 10, 100) including two reception parts (10, 40). In this case, the reception parts (10, 40) have a hollow box shape for receiving the brush units, and contain gargle (7) and disinfectant (60) therein, respectively. Further, a sealing unit is provided at a position around a mouth of each of the two reception parts (10, 40). The two reception parts (10, 40) ...
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FOOD PRODUCT HAVING INCREASED BILE ACID BINDING CAPACITY

(WO2003105600) 24.12.2003 A23L 1/09 GENERAL MILLS, INC.
A food product having enhanced cholesterol of triglyceride lowering properties comprising components that provide an increased affinity for binding bile acids. A first component is a starch selected from the group of cyclodextrins (beta, alpha or gamma cyclodextrins). A second component can be a dietary fibre such as a beta glucan or a sterol based compound such as sitosterol, stigmasterol or campesterol. The composition may be grain based with enhanced hypocholesterolemic properties. It may also comprise micro- and macro-nutrients (vitamins, minerals..) to provide a well-balanced food product that should be palatable and have a good mouth feel and texture. As an example cyclodextrins may be included in ready to eat cereals, mixes doughs an...
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MAGNETIC THERAPEUTIC DEVICE

(WO2003101317) 11.12.2003 A61N 2/06 EWING, David, L.
A method and apparatus for treating wounds including the steps of exposing a wound to a magnetic source (10). A device (400) for magnetizing water including a container (400) for holding water and a magnetic source (412) disposed about the container (400). A method of attaching a medical or dental appliance (516) including the steps of providing magnetized medical or dental cement (500) and appplying the cement (500) so as to affix an appliance (516) in a desired location. A magnetic therapeutic device (600) including an adhesive bandage (600) for covering a wound and a magnetic source (618) supported by the adhesive bandage (600). A magnetic mouthpiece (10) including a bite plate (12) and a magnet (16).
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MINIATURISED CAMERA

(WO2003101089) 04.12.2003 A61B 1/00 COBRA ELECTRONIC GMBH
The invention relates to a miniaturised camera with a photosensitive CCD matrix arranged in a rod- or tube-shaped housing and an integrated illumination device, in particular for application or use in a dental diagnostic instrument. In the head end of the rod-shaped housing a recess is provided, in which an optical plate with aperture openings or adjustable diaphragm is arranged. An objective lens is provided to the incident light side, behind the aperture opening and the CCD matrix is arranged, preferably in the head end, at a focal separation which is adjustable. According to the invention, the light necessary for illuminating the object is coaxially injected into the objective beam path. The objective lens and the CCD matrix are arranged...
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COMPOSITION AGAINST PERIODONTAL BACTERIA AND FOODS, DRINKS AND MOUTH WASHERS AGAINST PERIODONTAL BACTERIA CONTAINING THE COMPOSITION

(WO2003099304) 04.12.2003 A61K 8/36 MORINAGA &CO., LTD.
It is intended to provide a composition against periodontal bacteria, which has a high safety without showing any side effects and exhibits an excellent effect of killing periodontal bacteria without affecting the growth of nonpathogenic indigenous microorganisms in the oral cavity, and foods, drinks and mouth washers against periodontal bacteria. A composition against periodontal bacteria is blended with a cocoa fraction contained in cacao mass, a hot water-extract of the cocoa fraction, polyphenols originating in the cocoa fraction or free fatty acids originating in the cocoa fraction as the active ingredient. Then the obtained composition against periodontal bacteria is added to foods, drinks or mouth washers against periodontal bacteria...
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LOW-DUSTING INVESTMENT COMPOSITION MATERIAL

(WO2003099237) 04.12.2003 A61K 6/10 ELEPHANT DENTAL B.V.
The invention relates to a method for manufacturing a heat-resistant mold wherein heat-resistant investment material is inserted in a wax model manufactured in a conventional manner. The invention further relates to a low-dusting investment material, which low-dusting material is in particular heat-resistant. The investment material is applicable in dentistry, particularly for manufacturing molds.
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COMPOSITION FOR ENHANCING ORAL HEALTH

(WO2003097000) 27.11.2003 A61K 8/34 LG HOUSEHOLD &HEALTH CARE LTD.
Disclosed is composition for enhancing oral health, which includes 0.0001~10 wt % of Xanthorrhizol on the basis of the total weight of the composition, and 0.01~10 wt % of at least one antibacterial activity enhancer selected form the group consisting of alkyl sodium sulfate, sodium lauroyl sarcocinate and sodium methylcocoyltaurate. The antibacterial activity enhancer contained in the composition more effectively enhances antibacterial activity of Xanthorrhizol against causative bacterial of a decayed tooth or a peridental disease existing in the mouth, so the composition is very helpful for enhancing the oral health, for example the prevention or relief of a decayed tooth or a peridental disease or the restraint of foul breath.
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ORAL CARE COMPOSITIONS COMPRISING DICARBOXY FUNCTIONALIZED POLYORGANOSILOXANES

(WO2003094877) 20.11.2003 A61K 8/896 THE PROCTER &GAMBLE COMPANY
Disclosed are compositions and methods for treating and modifying surfaces and for enhancing delivery of active agents to surfaces treated with the compositions, which comprise siloxane polymers functionalized with pendant moieties comprising anionic groups, specifically carboxylic acid groups. When applied to a suitable surface, the present composition comprising the carboxy functionalized siloxane polymers forms a substantially hydrophobic coating on the treated surface. These polymers effectively deposit on surfaces that have cationic sites, which are capable of forming bonds or linkages with the anionic groups of the polymer. The treated surface becomes hydrophobic due to the deposition of the carboxy functionalized siloxane polymer, wh...
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CAPSULE CONTAINING A MIXER SUBSTANCE FOR BOTTLES CONTAINING PRESSURISED LIQUIDS

(WO2003093128) 13.11.2003 B65D 41/34 BORMIOLI ROCCO &FIGLIO S.p.A.
The capsule (3) comprises a lower cap (4) with a security strip (12) which inserts removably on a mouth (2) of a bottle. The upper part of the lower cap (4) is open and provided with a neck (4a) which couples with an upper cap (5), also having a security strip (13). A reservoir (8) is comprised within the upper cap (5) and has a breakable bottom (8a); the reservoir (8) also internally comprises a cutter (9). The upper cap (5) can move axially downwards with respect to the neck (4a) and the bottle, while it is prevented from moving upwards. The capsule also includes an anchoring between the reservoir (8) and the neck (4a) of the capsule when the reservoir is inserted in the neck (4a). The process comprises a stage of filling the bottle with ...
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TOOTH-CLEANING DEVICE

(WO2003090578) 06.11.2003 A46B 1/00 SKG ITALIA S.P.A.
The present invention relates to the field of tooth cleaning. According to the present invention a tooth cleaning device is provided, adapted to be introduced into the mouth. The tooth cleaning device comprises engaging means allowing it to be displaced all around the mouth by means of the tongue, thus performing a cleaning process.
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SEPARATOR FOR SHREDDED TOBACCO

(WO2003090569) 06.11.2003 A24B 1/04 COMAS-COSTRUZIONI MACCHINE SPECIALI - S.P.A.
A separator for shredded tobacco comprising a column (2) provided at its bottom with a perforated plate (6) inclined towards a discharge duct (8), and further provided with an entry duct (4) for the shredded tobacco and a feed pipe (10) for air which propels the shredded tobacco upwards, characterised in that the upper mouth of the column faces a mesh conveyor (18) movable substantially transversely to the vertical axis of the column, said conveyor forming an element by which the upward rise of the shredded tobacco is halted and is conveyed towards a member (30) for removing and conveying the tobacco.
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TEA POLYPHENOL BUCCAL TABLET FOR PREVENTING AND TREATING TOOTH DECAY AND ITS PREPARING METHOD

(WO2003086359) 23.10.2003 A61K 8/73 YU, Jiang
This invention relates to a tea polyphenol buccal tablet for preventing and treating decayed tooth and to its preparing method. The tablet is prepared with the raw material including: 1-7 weight part of tea polyphenol, 25-45 weight part of xylitol, 20 40 weight part of mannitol, 15-25 weight part of beta-cyclodextrin, 7-12 weight part of natural food additive and 0.5-2 weight part of lubricant. Its preparation process includes grinding beta-cyclodextrin in water, adding tea polyphenol before further grinding into paste, low temperature drying, grinding xylitol, mannitol and natural food additive to 400-600 mesh, mixing the said material, and then mixing the mixture with alcohol, granulating, drying at temperature below 60 C, mixing wit...
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MEDICAL COMPOSITIONS CONTAINING AN IONIC SALT

(WO2003086328) 23.10.2003 A61K 6/00 3M INNOVATIVE PROPERTIES COMPANY
A hardenable medical composition (preferably, dental composition) that includes an ionic redox polymerization system and at least one secondary ionic salt that includes a cation selected from the group consisting of a Group I ion, a Group II ion, an ammonium ion of the formula NR4+ wherein each R is H or a (C1-C4)alkyl group, and mixtures thereof.
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POLESTER/EPOXY COATED STAINLESS STEEL DENTAL CROWN

(WO2003086229) 23.10.2003 A61C 5/08 3M INNOVATIVE PROPERTIES COMPANY
A dental crown that includes a stainless steel shell sized to cover a tooth portion of a patient and a polymeric coating including a polyester/epoxy hybrid composition.
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AN APPARATUS FOR WASHING THE INTERIOR OF CONTAINERS MADE OF PLASTIC MATERIAL

(WO2003084685) 16.10.2003 B08B 9/34 R. BARDI S.R.L.
An apparatus for washing containers (1) made of plastic material with capacity ranging between 5 and 30 litres which may be provided with a handle (7) to facilitate its handling, comprises: - means for gripping the container (1) in upside down condition, i.e. with the mouth (9) oriented downwards, so shaped as to allow also a rotation of the container (1) about its own central longitudinal axis; - spraying means (4) for spraying suitable cleaning fluid inside the container (1) whilst said container rotates about its own central longitudinal axis, and is characterized in that the spraying means comprise at least a pair of movable nozzles (4), so shaped as to produce at least a pair of rotating jets of cleaning fluid which simultaneously pene...
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THERAPEUTIC AGENT DELIVERY COMPOSITIONS FOR BUCCAL CAVITY ABSORPTION OF PILOCARPINE

(WO2003084515) 16.10.2003 A61K 9/00 TRANSORAL PHARMACEUTICALS, INC.
A therapeutic agent delivery composition containing a functional buffer system for facilitating absorption of pilocarpine in the buccal cavity. More particularly, the composition is used to raise the pH of the buccal cavity so that the pilocarpine agent is delivered in a lipophilic form capable of crossing the buccal membrane. The delivery composition raises the pH of the buccal cavity through the implementation of a buffer system, which comprises a combination of two or more buffer agents. The agents of the buffer system are combined in a manner where the stronger basic agent is at relatively larger levels than that of a corresponding weaker base. The delivery composition may be administered as a chewing gum, where the pilocarpine is effec...
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INTRAORAL DENTAL RADIOLOGY POSITIONING DEVICE

(WO2003084421) 16.10.2003 G03B 42/04 DIEDERICH, Jennifer, A.
A receptor positioning device for taking dental bitewing radiographs of teeth inside a patient's mouth includes a rigid fixed structure having a collimation plate (12) defining a substantially rectangular opening (16). A receptor holding member (30) is adapted to receive a receptor, and an elongated arm (20) is adapted to receive and couple to the collimation plate. The elongated arm extends towards and couples with a rear portion of the receptor holding member, opposite the collimation plate, such that an unobstructed path is defined between the rectangular opening of the collimation plate and the receptor. A biting surface (22) is fixedly attached to a distal end of the elongated arm and adjacent to the receptor holding member such that t...
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METHOD OF JUDGING RISK OF PEIODONTAL DISEASE

(WO2003083472) 09.10.2003 A61K 38/17 TAKANO, Kunio
(1) A protein occurring in human saliva and being fractionated into a 35 kDa fraction by sodium dodecyl sulfate polyacrylamide gel electrophoresis, or a protein containing the amino acid sequence represented by SEQ ID NO:2; (2) a method of judging risk of periodontal disease characterized by comprising examining the presence/absence of the above protein in the saliva of a subject and judging risk of periodontal diseases based on the results; (3) a reagent for judging risk of periodontal disease which contains the above protein as a standard; and (4) a drug inhibiting the formation of dental calculus from dental plaque and an alveolar bone absorption inhibitor.
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PASTE POLYMERIZATION INITIATOR COMPOSITION, DENTAL OR SURGICAL ADHESIVE AND ADHESIVE KIT

(WO2003082931) 09.10.2003 A61K 6/00 SUN MEDICAL CO., LTD.
A paste polymerization initiator composition comprising 100 pts.wt. of an organic boron compound (A) being liquid at 25 C and 4 to 400 pts.wt. of particles of 0.001 to 50 m average diameter (B) being inert to the organic boron compound (A), the paste polymerization initiator composition having a consistency at 25 C, as measured under a load of 300 g in accordance with the method specified in ISO 4823, of 15 to 100 mm. This composition constitutes, for example, a dental kit together with a separately packaged polymerizable monomer. This composition enables safely using organic boron compounds, and further its use is very easy because of paste form.
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EXTENDED LIP WICKET SLIDER DELI BAG

(WO2003082693) 09.10.2003 B65D 33/14 PLIANT CORPORATION
A flexible reclosable container (20) with a header strip (70), fastener elements (32, 34), and a slider (48). The header strip (70) preferably extends from the mouth of the bag, and includes a line of weakness for easy tear off of the bag. The slider (48) and profiles (32, 34) are arranged such that the mouth of the bag is substantially open.
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DISPENSING APPARATUS AND CARTRIDGE

(WO2003082139) 09.10.2003 A61C 5/06 ORAPHARMA, INC.
A device (20) for the treatment of periodontal disease includes a handle (22) that has a configuration familiar to dental professionals, and a cartridge (24), that is locked into the handle (22) when used, typically delivery of a compositions, such as agents, as its tip (140) is deformable, typically from a circular to an oval shape so as to flatten.
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DUPLEX SHANK UTILIZING DEFLECTION CAUSED THEREON, TOOTH BRUSH, DENTAL FLOSS HOLDER, TUBE CLEANER, AND TWEEZERS

(WO2003079848) 02.10.2003 A46B 9/04 TASHIBU, kenzi
A duplex shank capable of increasing a width between fork-shaped opening ends by utilizing a deflection caused thereon by grasping, a tooth brush manufactured by using the shank for cleaning both faces of teeth, a dental floss holder capable of arbitrarily increasing the tensed width and tension of a dental floss, a tube cleaner, and tweezers, the duplex shank wherein a connection end (5) is formed by connecting two structural members (3) and (9) in a tuning fork shape and installing a pivot portion (4) functioning as a pivot at the middle position of the shank or the two structural members and the pivot portion are formed integrally with each other by injection molding, and the area of the shank between the pivot portion and the connection...
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MASK APPARATUS

(WO2003076020) 18.09.2003 A61M 16/06 SMITHS GROUP PLC
A face mask comprises a sealing collar (1) extending around the mouth with a shelf (4) extending under the nose supporting a gel insert (7) that makes sealing contact between the nostrils and a passage (6) through the shelf. A curved, rigid window (30) is a push fit in a central opening (2) of the collar (1) and has a gas inlet (33) attached with it so that the window can be removed or connected with the sealing collar as necessary. The collar (1) supported on the head by a harness (20) having two triangular portions (21) on opposite sides encircling respective ears.
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TOOTHPASTE COMPOSITION INCLUDING ACID RESISTANT CALCIUM CARBONATE AND A METHOD OF MAKING THE SAME

(WO2003075874) 18.09.2003 A61K 8/19 QUIMICA INDUSTRIAL BARRA DO PIRAI LTDA.
The present invention relates to a toothpaste composition including an abrasive system having an acid-resistant calcium carbonate abrasive material. The present invention also provides a method for making the toothpaste composition.
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HYGIENE INSTRUMENT FOR CLEANING AND POLISHING THE SURFACE OF THE TEETH AND THE COMPOSITE MATERIALS OF DENTAL FILLINGS

(WO2003075784) 18.09.2003 A61C 15/02 BACHMANN, Marc, William
Hygiene instrument for removing stains, cleaning and polishing the surface of the teeth and the composite materials of dental fillings. The structure of the hygiene instrument is made up of fibers and optionally a load of particles embedded in a resinous matrix giving the working surface of the hygiene instrument a continuous abrasive power.
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SYNTHETIC RESIN CAP, CLOSING DEVICE, AND PACKAGED BEVERAGE

(WO2003074380) 12.09.2003 B65D 41/32 ALCOA CLOSURE SYSTEMS JAPAN, LIMITED
A synthetic resin cap wherein the inner surface of the top plate of a cap main body consisting of the top plate and a sleeve depending from the peripheral edge thereof is formed with an inner annular seal projection adapted to be fitted on a vessel mouth and the inner peripheral surface of the sleeve is formed with a threaded portion for threaded engagement with the external thread in the vessel mouth, the threaded portion having a peripheral formation angle of 600-720 and being longitudinally divided in divisional sections into a plurality of divisional threaded portions, the divisional sections being peripherally substantially equally spaced; a closing device using the same; and a packaged beverage.
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CHLORHEXIDINE-BASED COLLUTORY FOR ORAL HYGIENE

(WO2003074018) 12.09.2003 A61K 8/23 CASTELLACCIO, Restituta
Collutory for oral hygiene comprising chlorhexidine and ascorbic acid, characterized in that it comprises also sodium metabisulphite and optionally also an alkali metal fluoride. The so prepared collutory, besides preventing the formation of dental plaque, avoids the drawback of the dark pigmentation thereof.
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LIGHT-CURING DEVICE WITH DETACHABLY INTERCONNECTING LIGHT APPLICATOR

(WO2003071975) 04.09.2003 A61C 13/15 ULTRADENT PRODUCTS, INC.
The light curing devices (10) of the invention include a gripping member (20) configured to be held in the hand of a user, a light applicator (30) configured in size and shape to be inserted within the mouth of a user, and a light source (60) configured to generate and emit sufficient radiant energy for curing light-sensitive compounds. The light curing device also include connection means (40) configured for detachably connecting the light applicator and the gripping member in such a manner as to prevent the light applicator from rotating with respect to the gripping member. The light applicator may include a light guide or a light source and corresponding mounting structure. The connection means may include mating bayonet (40A, 40B) forma...
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ANTIMICROBIAL COMPOSITION

(WO2003070919) 28.08.2003 A01N 63/02 BLIS TECHNOLOGIES LIMITED
This invention provides novel Streptococcus salivarius, compositions containing same, and use of S. salivarius strains as antimicrobial agents. The strains are bacterial inhibitors with respect to at least S. mutans and/or MS and therefore have a number of therapeutic applications. The applications include but are not limited to forming part of therapeutic formulations for use in controlling, treating, or preventing dental caries.
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PLASTIC WATER BOTTLE AND APPARATUS AND METHOD TO PREVENT BOTTLE ROTATION

(WO2003070579) 28.08.2003 B65B 7/28 FCI, INC.
A molded plastic container for carbonated and non-carbonated beverages and a bottle support plate for use in a rotary capping machine used to apply caps onto the upper threaded neck of one or more containers having a non-fully circular flange. The plastic container includes an upper mouth-forming portion (162), a cylindrical sidewall portion and a lower base-forming portion. The upper mouth-forming portion includes a non-circular anti-rotation flange adapted to at least partially inhibit full rotation of the container as cap is inserted on the container. The anti-rotation flange typically has an outer perimeter shape of a heptagon, The lower base-forming portion can include a variety of different configurations.
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BIODEGRADABLE BONE IMPLANT

(WO2003070292) 28.08.2003 A61K 6/087 BIOMATERA INC.
The present invention provides a method for making biodegradable and bioresorbable biomaterials that are also characterized by its malleability. Any desired shape can be obtained from this material, resulting from the specific composition of this invention. Therefore, the biomaterial of the present invention is very well suited to be used as in preparation of implants for dental applications, or as in the case of difficult accessible sites such as bone cavities. Composition of the biomaterial comprises an hydrophobic biopolymer, a compound having both hydrophilic and hydrophobic properties, bone regenerative entity that help in the bone regeneration. In addition, these biomaterials can be used as vehicle for the release of biologically acti...
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DENTAL ADHESIVE COMPOSITION

(WO2003070198) 28.08.2003 A61K 6/00 DENTSPLY INTERNATIONAL INC.
A composition including nanoparticles each having an acidic polymerizable siloxane moiety. For example, a hydrolysis stable, self-etching, self-priming dental adhesive composition including 90 to 10 percent by weight of an aqueous phase, and 10 to 90 percent by weight of acidic polymerizable nanoparticles. The acidic poylmerizable nanoparticles are obtainable by hydrolysis of a mixture containing one or more hydrolyzable organosilicon compounds wherein (i) at least a portion of the hydrolyzable organisilicon compounds contains one or more polymerizable groups and (ii) at least a portion of the hydrolyzable organisilicon compounds contain one or more acidic moieties.
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PINCH BOTTOM BAG WITH TEAR STRIP

(WO2003068618) 21.08.2003 B65D 30/08 STONE CONTAINER CORPORATION
A pinch bottom bag construction, for a multiwall bag (10), incorporating an easy open feature, which permits the controlled opening of a portion of the mouth opening of the bag, to create a spout-like opening, with the use of a tear string (44) disposed on the upper step of the manufacturer's opening.
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DEVICE FOR TREATING DRINKING WATER TO MAKE IT HOSTILE TO DENTAL PLAQUE

(WO2003068181) 21.08.2003 A61K 8/02 OWADES, Joseph, L.
A device for treating potable water contains a mixed buffer of a cation exchange resin in the hydrogen ion form and an anion exchange resin, a chelating agent and a sparingly soluble calcium salt, all contained in a porous, flow-through bag.
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COSMETIC LIP PRODUCT WITH SOUR FLAVOR

(WO2003068176) 21.08.2003 A61K 8/34 BONNE BELL, INC.
Methods for making a sour tasting cosmetic lip product containing one or more acids dissolved in a base composition, and the products formed thereby, are disclosed. The products possess a pleasing sour taste while not producing irritation or burning on the lips or mouth. Ingredients such as sunblocks, moisturizers and vitamins may be added to the compositions depending on the properties desired in the final product. The compositions according to the present invention comprise from about 2% to about 25% by weight acid and are preferably anhydrous.
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SELF-ETCHING PRIMER AND ADHESIVE BONDING RESIN

(WO2003068174) 21.08.2003 A61K 6/00 BISCO, INC.
Self-etching copolymerizable primer compositions are provided including compounds having polymerizable ethylenically unsaturated groups and acidic groups, and optionally comonomers and suitable solvents. Such compositions are used in conjunction with dental adhesives to provide one or multi-component dental systems capable of etching or decalcifying tooth dentin and enamel without the need for a separate rinse step. Methods of use of such compositions according to the present invention include application for priming and imparting enhanced adhesion between the primers, adhesives, and the tooth substrates such as dentin or cut or uncut enamel, and subsequently applied dental composites, restoratives or other dental components.
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A BAG DISPENSER

(WO2003068033) 21.08.2003 A47F 9/04 HYPERAMA PLC
A bag dispenser for a stack of pre-formed flattened bags comprises a base and an upstanding wall having first and second portions separated by a transverse bend. The bags have a detachable retention tabs and are disposed over the wall such that they are folded over the bend at a position intermediate the mouth and base ends. The bag stack being supported on each side of the bend by the first and second wall portions. A retention member on the second part of the upstanding wall is received in aligned apertures in the retention tabs of the bags so as to retain the stack of bags on the dispenser such that when the main body of the uppermost bag in the stack is pulled relative to the retention member it becomes detached from its retention...
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PLASTICINE COMPOSITION AND PROCESS FOR PRODUCTION THEREOF

(WO2003067558) 14.08.2003 G09B 19/10 KANEBO, LTD.
A plasticine composition which is free from oily odor and excellent in basic properties as plasticine such as softness, shape retention and adhesion and does not do harm to the human body even if it is brought into the mouth by mistake. The plasticine composition comprises (A) talc and/or calcium carbonate, (B) a solid wax, and (C) at least one binder selected from the group consisting of polybutene, natural rubber and isobutylene-isoprene rubber.
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DISPENSING DEVICE

(WO2003065967) 14.08.2003 A61H 35/02 WRIGHT, James Grant
A dispensing device is disclosed for liquid formulations which finds particular use as an eyewash station. The device (1) includes a container (2) with a neck (3) having a threaded portion (4). A shaped inner cap (5) includes a complementary threaded portion (6) to engage the threaded portion (4). A tube (7), open at both ends (8,9), is integral with the inner cap (5) and extends from the inner cap (5) to terminate near the base of the container (2). A first recess (10) extends around the exterior surface of the inner cap (5) at its lower end. A second recess (11) extends around the exterior surface of the inner cap (5) at approximately mid-length of the cap (5). An eyecup reservoir (12) includes an upper portion (13) shaped to accommodate ...
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A TEETH-CARE TOOTHBRUSH

(WO2003065845) 14.08.2003 A46B 15/00 JIN, Wenguang
The present invention discloses a teeth-care toothbrush, comprising a handle, a head and some permanent magnets. The bristles are arranged and fixed in a certain fashion on the head. The head is connected with one end of the handle detachably. In addition, one or more perforations are set up on the head to place the permanent magnets. Corresponding to the perforations, one or more cuneal perforations are set up on the one end of the head. The permanent magnets are fixed and placed in the cuneal perforations. The teeth-care toothbrush according to the present invention makes use of the magnetic therapy of the permanent magnets and the toothbrush which the people must use everyday to health care the mouth. Thereby it can realize b...
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CHEWING GUM AND CONFECTIONERY COMPOSITIONS WITH ENCAPSULATED STAIN REMOVING AGENT COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME

(WO2003063604) 07.08.2003 A23G 4/00 CADBURY ADAMS USA LLC
A composition in the form of a chewing gum composition or a confectionery composition containing an encapsulated stain removing aagent selected from anionic and non-ionic surfactants and methods of preparing and using the same to remove stains from dental material including teeth.
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METHOD FOR FORMING STRIPS OF CONTAINERS

(WO2003061945) 31.07.2003 B29C 49/00 SARONG SOCIETA' PER AZIONI
A method for forming strip containers, in which two continuous webs in thermoformable and heat-sealable material facing each other are indexed along a feed line through different operating stations (2, 3, 4, 5) that transform the webs into a continuous strip (1) of containers (A) each one of which is provided with a mouth. The containers are arranged according to two parallel rows that are opposed to a longitudinal median zone. The mouths of the containers of the upper row are arranged on the upper longitudinal edge of the strip and face upwards, whilst the mouths of the containers of the lower row are arranged on the lower longitudinal edge and face downwards. The invention enables productivity to be increased and methoding waste to ...
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A PROCESS FOR TREATING A SURFACE

(WO2003061908) 31.07.2003 A61C 3/025 EXA SA
A process for treating a surface (2) to clean or otherwise treat the surface (2) comprises a step of contacting the surface (2) with a particulate treating agent such that at least some of the particles (1) roll along at least a portion of the surface (2), wherein an angle of incidence of the particles (1) and the surface is between 0 and 60. The particles (1) are dimensioned to effect a rolling movement along the surface (2). The treating agent is substantially non-aqueous. The particles (1) comprise a precipitate or agglomerate of an insoluble alkali metal carbonate. The process comprises a blasting operation or a manual application. The use of the process of the invention in dental applications such as teeth whitening and plaqu...
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FLUORIDATED PRODUCTS

(WO2003061599) 31.07.2003 A23L 2/52 KALILI, Tom, K.
Provided are fluoridated products, including a beverage and a powdered composition for preparing the beverage as well as oral healthcare products. The powdered composition can be readily mixed with water to prepare a suitable fluoridated beverage or solution for making other products upon the addition of hydrogen fluoride. The powdered composition comprises a fluoride compound, an essential amino acid and a polyprotic acid, and most preferably vitamin C. A preferred method of preparing the fluoridated solution includes adding hydrogen fluoride to the water base, as the presence of the hydrogen fluoride greatly enhances the fluoride availability, and then adding the remaining components. The solution can be used as a fluoridated beverage or ...
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EDIBLE COMPOSITIONS CAPABLE OF REMOVING ORAL BIOFILM

(WO2003059302) 24.07.2003 A23G 1/00 YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM
An edible and/or chewable article of manufacture containing at least one food grade substance having adsorption affinity towards at least one dental plaque (biofilm) constituent and capable of reducing and/or removing the oral biofilm while present in the mouth. Particular articles of manufacture are chewing gums, sweets, candies, candy- and other nutritional bars, ice creams, chocolates, confectionery and bakery/pastry products, honey, dairy products and beverages, and oral hygiene products such as tooth pastes, oral gels and mouthwashes.A chewing gum comprises a conventional gum base and at least one food grade active substance having adsorption affinity towards at least one dental plaque (biofilm) constituent (bacteria and proteins and b...
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FOOD PROCESSING SURFACE CLEANING SYSTEM AND METHOD

(WO2003057378) 17.07.2003 A61L 2/02 FOOD PRO SYTEMS LIMITED
The invention provides food processing surface (40) cleaning system and related methods and uses. The system comprises: a vacuum source; a cleaning head (101), having walls (102, 106) defining a vacuum chamber (108) in communication via a vacuum line (150) with the vacuum source, the vacuum chamber (108) having an open vacuum mouth; and means for supplying a pressurised cleaning fluid via a fluid line (28) to one or more cleaning fluid outlets (26) within the vacuum chamber (108), the cleaning fluid outlets (26) being directed to spray cleaning fluid towards the vacuum mouth; whereby the vacuum mouth may in use be positioned near or against a food processing surface (40) to allow sprayed cleaning fluid to contact the su...
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COMPOSITION USED FOR COMBATING CHOLESTEROL AND IMPROVING DIGESTION

(WO2003057230) 17.07.2003 A23L 1/30 THUROT, Philippe, Jean, Louis
The invention relates to the fields of health and nutraceuticals. At least one ground material, extract, composition, or formulation made of grains from a MORINGA-type plant is used for medical, pharmaceutical, health-related, or nutrition-related purposes in or for preparing a medicament, functional food, or a food complement or supplement or for preparing a composition or formulation. Said ground material, extract, composition, or formulation is to improve and accelerate digestion, combat indigestion and flatulence, accelerate the intestinal transit, eliminate constipation, reduce the absorption of lipids, reduce the cholesterol level in the blood without taking away appetite or causing dryness in the mouth while combating said dryness.
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REMOVABLE DENTAL MODELS

(WO2003057068) 17.07.2003 A61C 13/00 3M INNOVATIVE PROPERTIES COMPANY
An apparatus and method of use that include a dental model, a support that includes a mounting surface and a stretch release pressure sensitive adhesive located between the dental model and the support. The stretch release pressure sensitive adhesive attaches the dental model to the mounting surface. In an additional embodiment, a highly extensible and substantially inelastic backing having a layer of the stretch release pressure sensitive adhesive is used to attach the dental model to the mounting surface. The dental model and the support are separated without damage by stretching the stretch release pressure sensitive adhesive at an angle no greater than about 35 degrees from the mounting surface.
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PRECIPITATION HARDENABLE AUSTENITIC STEEL

(WO2003056053) 10.07.2003 C22C 38/00 SANDVIK AB
The present invention relates to a stainless steel alloy, more precisely a highstrength stainless, precipitation hardenable, austenitic, stainless alloy, containing a well adjusted amount of aluminium and a high silicon content and which has the following composition (in weight-%): C 0-0.07 Si 0.5-3.0 N 0-0.1 Cr 15.0-20.0 Ni 7.0-12.0 Al 0.25-1.5 Cu 0 = Cu = 4.0 Mn 0-3.0 Mo 0-2.0 Ti 0-1.0 and the balance Fe together with normally occuring impurities and additives and a product that is reduced by cold working, especially drawing, without intermediate heat treatment, the strength of which increases by final heat treatment at 300 C to 500 C by not less than 14 %, that shows a Md30-value of between -55 and -100, a loss of force t...
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PRECIPITATION HARDENABLE AUSTENITIC STEEL

(WO2003056052) 10.07.2003 C22C 38/00 SANDVIK AB
The present invention relates to a stainless steel alloy, more precisely a high-strength stainless, precipitation hardenable, austenitic, stainless alloy, containing a well adjusted amount of aluminium and a high silicon content and which has the following composition (in weight-%): C 0-0.07 Si 0.5-3.0 N 0-0.1 Cr 15.0-20.0 Ni 7.0-12.0 Al 0.25-1.5 Cu 0=Cu=4.0 Mn 0-3.0 Mo 0-2.0 Ti 0-1.0 and the balance Fe together with normally occurring impurities and additives and a product that is reduced by cold working, especially drawing, without intermediate heat treatment, the strength of which increases by final heat treatment at 300C to 500C by not less than 14 %, that has a loss of force that is smaller than 3.0 % at 1400 N during 2...
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AMORPHOUS SILICA

(WO2003055802) 10.07.2003 A61K 6/00 INEOS SILICAS LIMITED
An amorphous silica suitable for use in a dental composition has a weight mean particle size in the range 3 to 15 gm with at least 90 per cent by weight of particles having a size below 20 gym, a Radioactive Dentine Abrasion (RDA) determined on an aqueous slurry of the silica powder of 100 to 220, a Pellicle Cleaning Ratio (PCR), when incorporated in a dental composition at 10 per cent by weight, greater than 85, the ratio of PCR to RDA being in the range 0.4:1 to less than 1:1 and having a Plastics Abrasion Value (PAV) in the range 11 to 19. A silica having the above properties is prepared by a precipitation route. The silica made available by the invention is also useful as an anti blocking agent in plastics.
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DEVICE FOR TRAILER COUPLING

(WO2003055704) 10.07.2003 B60D 1/02 VBG AB
The invention relates to a damping element (7) for a trailer coupling (1) of the kind comprising a coupling eye (2) arranged on a drawbar (3) of a trailer, a coupling mouth (4) arranged on a towing vehicle and adapted to receive the coupling eye (2), and an engage-ment means (5) arranged in the coupling mouth (4) and adapted to releasably engage the coupling eye (2) when the latter is inserted in the coupling mouth (4). The damping element (7) is plate-like and has at least one first supporting portion (8) adapted to bear against a surface in the coupling mouth (4) oriented essentially towards the coupling eye (2), at least one second supporting portion (9) adapted to bear mainly against the upper side of the coupling eye (2), and at le...
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COMPOSITION FOR MOUTH

(WO2003055459) 10.07.2003 A61K 8/19 KAO CORPORATION
A composition for the mouth which comprises the following ingredients (A), (B), and (C): an inorganic acid and/or organic acid, an anionic surfactant, and at least one member selected among polyglycerol/fatty acid esters, sorbitan/fatty acid esters, ethers of C6-14 polyoxyethylenes with higher alcohols, polyoxyethylene/fatty acid esters, and polyoxyethylene/polyoxypropylene copolymers. The composition is significantly reduced in the astringency attributable to the anionic surfactant.
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PHARMACEUTICAL SUSPENSION FOR ORAL ADMINISTRATION

(WO2003053403) 03.07.2003 A61K 9/00 PHARMACIA CORPORATION
A pharmaceutical composition suitable for oral administration is provided, the composition comprising an aqueous medium having suspended therein a solid substance of low water solubility in particulate form, and further comprising a suspending agent and at least one pharmaceutically acceptable water-soluble or swellable nonsurfactant polymer, the total amount of all such polymers present being ineffectibve to (a) increase viscosity of the composition to a degree that significantly impairs pourability, or (b) significantly increase rate of sedimentation or phase separation, of the composition. The composition has improved mouth feel.
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METHOD OF PRODUCING OBJECTS THROUGH FREE FORMING USING POWDERS

(WO2003053102) 26.06.2003 A61C 13/30 CERMA-TECH LTD.
An improved method of free form manufacturing is disclosed, including the dispensation of two powders each of the two powders having a different average size. A large average size particle powder is used to define, layer by layer, the structure of an incipient part whereas a small average size particle powder is used to fill interstitial spaces in the layers of large average particle size powder. Also, a method of manufacturing objects made of a plurality of closely fitting parts using FFM is disclosed where non-sinterable composition is dispensed in the location of incipient inter-part seams. Also, an easily removable dental post is disclosed. The dental post is provided with a cavity that when necessary to remove, the cavity acts as a rea...
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HERBAL COMPOSITION FOR IMPROVING ORAL HYGIENE, AND METHODS OF USING SAME

(WO2003052114) 26.06.2003 A61K 8/97 WOLFSON, Philip, E.
Compositions based on Heliopsis longipes root used orally in treating xerostomia, for dry mouth, increasing salivation, alleviating dry mouth, and in maintaining or improving oral hygiene; as local contact anesthetics; as a cough suppressant, and as an oral sensate-producing desirable sensations in the oropharynx. The herbal composition includes an extract from Heliopsis longipes root and an oral carrier for the extract. A suitable amount of extract is from about 0.01 to about 10 weight percent of the overall composition. A variety of compositions include an oral carrier; preferred compositions are: 1) a gum with a solid exterior and a liquid center, both the exterior and center containing an effective amount of the extract composition; 2) ...
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DENTAL COMPOSITION BASED ON A COLLOIDAL SILICA SOLUTION IN CONTINUOUS SILICON PHASE

(WO2003051317) 26.06.2003 A61K 6/093 RHODIA CHIMIE
The invention relates to dental compositions which can be used to produce dental prostheses and for dental restoration. The inventive compositions comprise: (1) a concentrated silica solution comprising colloidal amorphous silica particles in at least one continuous silicon phase, consisting of polymerisable and/or crosslinkable silicon polymer and/or oligomer; (2) at least one photosensitiser; and (3) a cationic initiator which is selected from among those comprising a cationic entity selected from onium salts having formula (I): [(R1)n - A - (R2)m]+
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DEVICE FOR DENTAL APPLICATIONS

(WO2003051316) 26.06.2003 A61K 6/00 KANCA, John, III
Etching compositions, curable compositions, packaged products and methods of use for the treatment of bone substrate, i.e., teeth, are described. The etch solutions generally include an inorganic acid, an organic acid and either a solvent, a surfactant or mixtures thereof. The curable composites include reactive monomers and crosslinking agents that are effective to adhere to the surface of the treated substrate. The methods of the invention provide the ability to modify a bone or bone-like surface so that the curable composition, such as an adhesive resin, can be used in combination with a restorative material.
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ADHESION INHIBITION OF FUNGI

(WO2003051125) 26.06.2003 A01N 27/00 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to the use of substances that influence fungal dimorphism for reducing the adhesion of fungi to surfaces. The invention also relates to washing and/or cleaning agents, textile treating agents and cleaning agents for mouth, teeth or dentures and to the use of said substances in said agents. The inventive substances are selected from propolis extracts, plant extracts, cinnamic acid and the derivatives thereof, monoterpenes, sesquiterpenes and diterpenes and the derivatives thereof, especially fucoidine, anethol, geraniol, farnesol or farnesol acid.
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A HOLE CLEANING AND/OR FORMING TOOL

(WO2003050360) 19.06.2003 E02F 3/02 MAHER, Graeme, Duncan
A tool for cleaning and/or forming holes, the tool having a shaft,(13) the shaft having a lower end and at least two buckets (15, 16) attached to adjacent the lower end of the shaft (13), each bucket having an open mouth which extends radially from the axis of the shaft (13) such that rotation of the shaft about its axis causes rotation of the buckets (15, 16) causing dirt to pass through the mouth of each bucket.
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USE OF AN ANTIMICROBIAL GLASS CERAMIC FOR DENTAL CARE AND ORAL HYGIENE

(WO2003050053) 19.06.2003 C03C 4/00 SCHOTT GLAS
The invention relates to the use of a glass ceramic, in particular a glass ceramic powder, whereby the starting glass has the following composition (in wt. % relative to the oxide): Si02? 30-70 wt. %, Na2?O 0-40 wt. %, K2?O 0-40 wt. %, CaO 5-40 wt. %, MgO 0-40 wt. %, Al2?O3? 0-5 wt. %, P2?O5? 1-20 wt. %, B2?O3? 0-5 wt. %, ZnO 0-10 wt. %, 0 to 30 wt. % XFy?, where X can be Na, K, Mg, or Ca and y = 1 or y = 2, for application in the field of oral hygiene and dental care.
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A NOVEL HERBAL CHEMICAL COMPOSITION FOR THE TREATMENT OF CANCER

(WO2003047608) 12.06.2003 A61K 31/365 COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
The present invention relate to a novel synergistic composition of lignans exhibiting anticancer activities for breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate cancer obtained from the plant extract of Cedrus deodra, said composition comprising of (-)- Matairesinol in the range of 9 to 13 % by weight, (-)- Wikstromol in the range of 75 to 79 % by weight, Dibenzylbutyrolactol in the range of 7 to 11 % by weight, and Unidentified material in the range of 2.6 to 3% by weight; further, the synergistic composition of lignan is used in combination with pharmaceutically acceptable carriers for inhibiting growth of various human cancer cell lines selected from breast, cervix, neuroblastoma, colon, liver, lung, mouth, ov...
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SMALL INTERDENTAL CLEANER CAPABLE OF BEING HOUSED IN VARIOUS DENTAL FLOSS CONTAINERS

(WO2003047495) 12.06.2003 A61C 15/00 KAWASE, Shiro
Dental floss and its implement are desirably be integrated. A main issue is to be able to house the implement as well as dental floss in various types of dental floss containers for convenience of storing/carrying, and another issue is to provide a strength superior to conventional implement functions can offer and a simple and economical method of application. This requires that the shape of the implement be simple, dwarfed and thin. For those purposes, dental floss having knot-like locks formed in advance is used. The implement has no wasteful structure including a long handle, except for lock receivers engaging the locks. It is molded such that a curve-free flat plate is formed with only U-shaped notches through whi...
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GYPSUM CASTING COMPOSITION AND METHOD OF CASTING

(WO2003046104) 05.06.2003 A61C 9/00 DIESSO, Michael
An aqueous gypsum dental casting composition comprising gypsum (11) and water wherein (a) one or more of a first compound is mixed in the gypsum in container (10) and/or water; or (b) one or more of the first compound and one or more of a second compound are mixed in the gypsum and/or water; or (c) one or more of the first compound and one or more of an acid are mixed in the gypsum and/or water; or (d) one or more of the first compound and one or more of the second compound and one or more of the acid are mixed in the gypsum and/or water; or (e) two or more of the acids and one or more of the second compound are mixed in the gypsum and/or water; and (f) the gypsum and water are maintained separately and mixed when casting is to be prepared....
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DENTIFRICE COMPOSITIONS

(WO2003043517) 30.05.2003 A61K 9/08 DANA, Frederic
The present invention relates to oral care compositions which provide a means to deliver actives which are useful in the prevention, treatment and/or management of dental and related tissue conditions, including dental caries, dental cavities, microbial flora, tartar, periodontal and related gum disease. In addition, the present invention may be used in the healthy maintenance of teeth and gums. Further aspects of the present invention are related to the present compositions being useful to whiten teeth and otherwise favorably impact the cosmetic appeal of the teeth and gums of a subject or patient. A further aspect of the present invention is directed to the inclusion of effective amounts of colostrum in dental care compositions for the un...
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ELECTRICAL BOX WITH RECESSED FACEPLATE

(WO2003043139) 22.05.2003 H01R 13/447 GATES, Clark, H., II
An electrical box with recessed faceplate having a one-piece recessed faceplate (2) and adapted to accommodate a two-piece recessed faceplate (25). A rear portion (8) containls channels (9) on the top (5), bottom (6), and sides (7). A connecting wall (1503) attaches the rear portion (8) to the front portion (11). The connecting wall (1503) extends beyond the rear portion (8) and preferably contains one or more apertures (19, 20) to accommodate releasable fasteners such as screws (10). These apertures (19, 20) and the channels (9) assure that no screws (10) or analogous components or another type or relesable fastener are exposed within the box (1). The two-piece recessed faceplate (25) has an inner portion (45) and an outer portion (24) whi...
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DEVICE AND METHOD FOR FORMING MOUTH GUARD

(WO2003041944) 22.05.2003 A63B 71/08 UENO, Masato
A device and a method for forming a mouth guard capable of preventing air from mixing therein and having a high forming accuracy, the device comprising a container (101) having an openable sealed space formed therein, a porous plate (118) disposed in the container in liftable state and having a chin pattern (121) placed thereon, a substrate (116) having a space (119) communicating with a sealed space through only the porous plate from the lower surface of the porous plate, an air compressor (114) for feeding air into the container, a vacuum pump for discharging air through the space of the substrate, an air cylinder (124) for liftably driving the substrate, a formed sheet (129) formed in contact with the chin pattern when the substrate is r...
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POWDERED MATERIAL AND CERAMIC MATERIAL MANUFACTURED THEREFROM

(WO2003041662) 22.05.2003 A61K 6/06 DOXA AKTIEBOLAG
Powdered material, the binder phase of which mainly consists of a cement-based system, which powdered material has the capacity following saturation with a lilquid reacting with the binder phase to hydrate to a chemically bonded ceramic material, preferably for dental purposes. According to the invention the powdered material has a composition and/or structure suitable for giving the ceramic material translucence in the hydrated state. The invention also relates to the ceramic material produced by hydration of the powdered material.
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TOOTH-CLEANING PAPER COMBINED WITH DENTAL FLOSS

(WO2003041608) 22.05.2003 A61C 15/04 KTNC CO. LTD
Disclosed is a tooth-cleaning paper combined with a dental floss, characterized by combining the dental floss functioning to remove interdental debris to the tooth-cleaning paper for use in scrubbing food debris stuck onto the teeth. Thereby, food debris stuck onto or held between the teeth is easily removed while the mouth is hidden with the cleaning paper, thus not giving other persons an unpleasant feeling. Further, the dental floss which conventionally suffers from difficult storage and excessive use due to slipping thereof is easily and economically used in state combined to the cleaning paper.
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DENTAL DEVICE

(WO2003041534) 22.05.2003 A46B 5/06 SANTACRUZ, Karen
A dental device (10) that provides effective teeth and gum cleaning when the device (10) is chewed, rotated, and/or brushed across the teeth is disclosed. The device (10) includes a body (12) presenting a multifaceted bristle-supporting surface (20) extending substantially around the circumference of at least a portion of the body (12). The device (10) further includes bristles (14) fixed relative to, and extending from, the facets (24, 26) of the bristle-supporting surface (20). In the preferred embodiment, the body (12) includes a base (16) and a handle (18) extending from one end of the base (16). The base (16) supports the bristle-supporting surface (20) around its circumference and includes bristles (14) extending from the end opposite...
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ORODISPERSIBLE TABLET HAVING HIGH HOMOGENEITY AND THE PREPARATION METHOD THEREOF

(WO2003039520) 15.05.2003 A61K 9/00 ETHYPHARM
The invention relates to a rapid-disintegrating tablet of the type which is intended to disintegrate in the mouth on contact with the saliva in less than 40 seconds, preferably in under 30 seconds, and which forms an easy-to-swallow suspension. The inventive tablet is made from at least one active material which takes the form of coated microcrystals or microgranules and a mixture of excipients in the form of grains. The aforementioned mixture of excipients has the following composition: between 60 and 85 % of a diluent; between 3 and 20 % of a decomposing agent; between 1 and 8 % of a sweetening agent; between 0 and 5 % of a gliding agent; between 0 and 10 % of a binder; and between 0 and 10 % of a permeabilising agent, a swelling agent an...
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SOLID ORAL ANTI-TARTAR AND ANTI-PLAQUE COMPOSITIONS

(WO2003039503) 15.05.2003 A23G 3/00 PERFETTI VAN MELLE S.P.A.
Oral formulations in the form of chewing gum comprising: a. polyphosphates; b. hydrated silica; c. a source of fluoride ions; d. a polymer derived from chitin, or other naturally occurring hydrocolloids or a mixture thereof; e. optionally extracts or active ingredients of vegetable origin and/or antibacterial/disinfectant agents. The compositions of the invention are useful as adjuvants in dental hygiene, in particular to reduce tartar deposits
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MINI-BRUSH FOR INTERDENTAL CLEANING AND CARE

(WO2003039391) 15.05.2003 A61C 15/00 LAGOS GALVAN, Flavio, Amrico
The invention relates to a mini-brush for interdental cleaning and care. Said mini-brush comprises a handle having an interdental brush disposed at one end thereof which is provided with bristles that gradually diminish in size. The smallest of said bristles are disposed at the most distal point of the device, while the other end thereof comprises a truncated pyramidal point which is used to massage the gums, said end taking the form of a triangle with a rounded tip. The inventive mini-brush is made from plastic materials and the pyramidal point thereof is made from a foam material that can hold gels or medicaments which are to be applied in the mouth of the user. The aforementioned pyramidal point can comprise an oval hole or groove for at...
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METERING DEVICE FOR METERING A PASTY SUBSTANCE

(WO2003039312) 15.05.2003 A47K 5/12 MEEUWENOORD, Pieter, Adriaan
The invention relates to a metering device (1) for metering a pasty substance. The metering device (1) is characterised in that the pressure device (6, 23) comprises a gear rack (6) provided with a rotating wheel (7) connected to it, and the gear rack (6) acts as a piston rod. An advantage of the metering device (1) is that a quantity of pasty substance can be metered accurately by rotating a rotating wheel (7). The metering device (1) is suitable in particular for use in sanitary rooms as a toothpaste dispenser.
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SINGLE-COMPONENT DENTAL COMPOSITION FOR DESENSITISATION OF THE EXPOSED DENTIN

(WO2003037283) 08.05.2003 A61K 7/16 ITALMED S.N.C. DI GALLI G. &PACINI G.
A dental composition for treatment of dentinal hypersensitivity. It comprises at least an insoluble micronised fluorine salt, with crystals size less than 5 microns, and at least a soluble potassium salt. This way, the effect of mechanical obliteration is carried out by the insoluble micronised fluorine salt that penetrates the tubular orifices, whereas the depolarising action of the nervous fibres is carried out by the soluble potassium salt.
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MINIATURIZED CAMERA EQUIPPED WITH A TUBULAR OR BAR-SHAPED HOUSING

(WO2003036944) 01.05.2003 A61B 1/05 COBRA ELECTRONIC GMBH
The invention concerns a miniaturized camera equipped with a photosensitive CCD matrix arranged in a tubular or bar-shaped housing and an integrated illuminating device, for use in particular in a dental diagnostic instrument. The front end of the bar-shaped housing comprises a recess wherein is inserted an optical plate. The optical plate includes at least a non-transparent coating in the visible spectral range, said coating being interrupted for a diaphragm aperture of minimal diameter and for larger illumination apertures arranged around the diaphragm aperture. On the light input side behind the diaphragm aperture is a lens, preferably directly mounted on the plate, and the CCD matrix is arranged inside the front end, spaced apart by som...
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COMPOSITION CONTAINING HORSE CHESTNUT EXTRACT FOR ANTI-ANGIOGENIC AND MATRIX METALLOPROTEINASE INHIBITORY ACTIVITY

(WO2003035092) 01.05.2003 A61K 9/20 KIM, Min-Young
The present invention relates to a composition containing Horse chestnut extract that inhibits angiogenesis and matrix metalloproteinase activity. The Horse chestnut extract of the present invention inhibits angiogenesis and activity of matrix metalloproteinase, so that it can be applied to treat disease related to angiogenesis and matrix metalloproteinase.
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HYDROLYSIS STABLE SELF-ETCHING, SELF-PRIMING ADHESIVE

(WO2003035013) 01.05.2003 A61K 6/00 DENTSPLY DETREY GMBH
An aqueous one-pack self-etching and self-priming dental adhesive composition having a pH of at most 2, which comprises: (i) a polymerizable N-substituted alkylacrylic or acrylic acid amide monomer which optionally contains an inorganic acidic moiety selected from a phosphonic acid moiety or a sulfonic acid moiety, and (ii) a curing system.
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COMPOSITION EXHIBITING ENHANCED FORMULATION STABILITY AND DELIVERY OF TOPICAL ACTIVE INGREDIENTS

(WO2003034979) 01.05.2003 A61Q 11/00 SOL-GEL TECHNOLOGIES LTD.
A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 micron. The core of each microcapsule includes at least one active ingredient, and is encapsulated within a microcapsular shell. The shell is comprised of at least one inorganic polymer obtained by a sol-gel process, and the shell protects the active ingredient before topical application and is designed to release the active ingredient from the microcapsules following application. The composition is useful in encapsulating active ingredients, such as benz...
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INCREASED PEROXIDE CONTENT TOOTH BLEACHING GEL

(WO2003032857) 24.04.2003 A61K 6/00 DISCUS DENTAL, INC.
A two-component tooth whitening system which incorporates an increased peroxide content, wherein the components are adapted to be mixed and applied to the teeth from a dental bleaching tray is provided. A first component includes both carbamide peroxide and hydrogen peroxide and a second component comprises an orally compatible activator gel.
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BAG

(WO2003031281) 17.04.2003 B65D 30/08 CARTER HOLT HARVEY LIMITED
A lie flat bag (10) assembly of a kind having a plastics pouch (29) within a block bottom factory finished end (11) (the 'bottom end') protective bag, the pouch (29) and the protective bag (13) having their mouths opening in the same direction, the bag (10) being characterised in that (i) the protective bag (13) has at the customer fill end (the 'top end') a closure flap (12) from one of its panels capable of being folded across the mouth of the protective bag (13) to lap part of another panel thereby, when adhered thereto, to effect at least a substantial closure of the mouth of the protective bag (13), (ii) at least one of the lapping surfaces (23A) (ie; of at least part of the closure flap (12) and part of said another panel (24)) is of ...
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TOOTH AND MOUTH CLEANER

(WO2003030765) 17.04.2003 A61C 17/02 CHOW, Shau-Din
A method of cleaning teeth and the mouth including the steps of filling the mouth with a fluid, locating an ultrasonic generator within the mouth and causing the generator to operate which, in turn, causes ultrasonic vibrations of the water and cleaning of objects which have the vibrating water impinging thereon and apparatus therefore.
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DISPENSER FOR HIGHLY VISCOUS FLUIDS

(WO2003030699) 17.04.2003 B05B 11/00 PEDERSEN, Erik
A dispenser for a highly viscous fluid, in particular toothpaste contained in a collapsible tube (100). The collapsible tube has a body part defining a storage cavity (C3) for said highly viscous fluid, an a neck part (200) with an external shoulder (201), where the neck part (200) has a passage (200a) through which the fluid may be removed. The dispenser comprises an adaptor (2), a pump, and tube gripping means (6). The pump comprises a pump mechanism (3) and a pump tube (4) connected to the pump mechanism (3) and the tube gripping means (6) is adapted to grip the neck part (200) of the collapsible tube (100), and hold and secure the collapsible tube (100) in a substantially vertically suspended position. The gripping means (6) and the pum...
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DISPENSER PUMPS

(WO2003028898) 10.04.2003 B05B 11/00 RIEKE PACKAGING SYSTEMS LIMITED
A pump dispenser suitable for dispensing toothpaste in which a pump chamber (4) has a resiliently flexible flap outlet valve (64) leading into a discharge passage (61, 62, 63) leading to a discharge nozzle (151). The discharge nozzle (151) features a closure valve (16) in the form of a concave wall (162) with radial slits (165) which opens only under appreciable forward pressure. When released, the closure valve (16) closes and retracts forcibly, giving a clean cut-off of product and a degree of backflow via the large outlet valve area of the flap valve (64) as it closes.
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COMPOSITIONS USED TO ALLEVIATE XEROSTOMIA AND TO TREAT DISORDERS ASSOCIATED WITH SAME

(WO2003028699) 10.04.2003 A61K 33/10 LACER, S.A.
The invention relates to novel fluid compositions that are used to alleviate xerostomia and to treat disorders associated with same. The inventive compositions contain: a) saliva substitute saline components which are selected from among sodium chloride, potassium chloride, sodium bicarbonate, monobasic potassium phosphate and bibasic potassium phosphate; b) components that stimulate saliva formation which are selected from among citric acid or the alkaline metal salts thereof and malic acid or the alkaline metal salts thereof; c) oral antiseptic agents which are selected from among triclosan, chlorhexidine and the salts thereof, benzalkonium and the salts thereof and cetylpyridinium chloride; d) anti-cavity components which are selected fr...
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ORAL COMPOSITION FOR TREATING SENSITIVE TEETH

(WO2003026601) 03.04.2003 A61K 8/24 LG HOUSEHOLD &HEALTH CARE LTD.
The present invention relates to an oral composition which may prevent or treat sensitive teeth. The oral composition contains potassium phosphates, wherein potassium ions inactivate dental nerves to relieve temporary pains, and phosphates not only prevent the exposure of dentinal tubules, which is the basic cause of sensitive teeth, but also block the exposed dentinal tubules. The oral composition further comprises ursodesoxycholic acid, thereby improving the effect of relieving the pain caused by sensitive teeth.
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METHOD AND TOOLS FOR ORAL HYGIENE

(WO2003026528) 03.04.2003 A45C 3/06 CERAMOPTEC INDUSTRIES, INC.
A method and material for self-cleaning of the teeth and mouth using a source of light (14) in the visible range in conjunction with a photosensitive oral hygiene composition possessing a broad absorption spectrum in the visible range. The invention selectively eliminates harmful bacteria by use of a photosensitive agent and a light source (14). The present invention involves the use of a light-providing dental device to activate a photosensitive agent and destroy harmful bacteria in the oral cavity. It prevents or deters oral diseases, inflammations, and infections.
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ORAL COMPOSITIONS PROVIDING ENHANCED OVERALL CLEANING

(WO2003024415) 27.03.2003 A61K 8/24 THE PROCTER &GAMBLE COMPANY
Disclosed are oral care compositions and methods for overall cleaning, whitening and preventing, reducing or removing surface deposited stains on natural teeth and dental prosthesis, the compositions comprising in an orally acceptable carrier at least 0.1% by weight of a water-soluble or water-dispersible copolymer prepared by copolymerizing one or a mixture of vinyl pyrrolidone (VP) monomers with one or a mixture of C1-C19 alkyl carboxylic acid (AC) C2-C12 alkenyl ester monomers. Preferably, the compositions further comprise one or a mixture of other oral care agents selected from a water soluble alkali metal or ammonium tripolyphosphate in an amount at least about 0.5% by weight of the composition, an abrasive, preferably a precipitated s...
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METHOD AND BLOW-MOULDING STATION FOR THE FINAL BLOWING OF A GLASS CONTAINER

(WO2003022756) 20.03.2003 C03B 9/193 HEYE GLAS GMBH
A gob (12) is blown to form a glass container (19) in a blow mould (2) of a blow-moulding station (1). The blow mould (2) has blow-mould halves (3, 4) and a block structure (18), which is not divided longitudinally and which is encompassed by said mould halves (3, 4) when the blow mould (2) is closed. Compressed air (15) can be introduced into the interior of the gob (12) by means of a blowing head (13), until the finished glass container (19) has achieved its final form. To strip the glass container (19) from the mould, said container is grasped by its mouth (11) by a removal mechanism. The blow-mould halves (3, 4) are then opened and the block structure (18) is displaced downwards until it reaches a stripping position.
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STABLE ORAL CARE COMPOSITIONS COMPRISING CHLORITE

(WO2003022256) 20.03.2003 A61K 8/20 THE PROCTER &GAMBLE COMPANY
Stable topical oral compositions comprising at least a minimally effective amount of chlorite ion are disclosed, wherein the pH of the final composition is greater than 7, the composition is essentially free of chlorine dioxide, and the composition is stable against loss of chlorite for a period of at least one year under normal storage conditions at about 25C or for a period of 3 months under accelerated storage conditions at about 40 C. Preferably the compositions further comprise a flavor system, which is stable against degradation by chlorite. The compositions are formulated as therapeutic rinses, especially mouth rinses, as well as toothpastes, gels, tooth powders, chewing gums, mouth sprays, lozenges (including breath mints)...
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A DEVICE BY WAY OF EXAMPLE FOR PERSONAL HYGIENE

(WO2003022094) 20.03.2003 A45C 11/18 SAFECARD ApS
There is disclosed a device (2), in particular for personal hygiene and adapted for keeping in wallet, pocket, bag, drawer, glove compartment or similar place, where the device is preferably designed as a credit card in size, where the device (2) has a dis-play surface on one side intended for commercial utilisation, and where the device on the other side has one or more hygienic articles (4) which externally are covered by means of one or more film pieces (6) consisting of preferably easily removable (peelable) plastic or metal film. In a simple way is hereby achieved a new and im proved device enabling persons to carry with them one or more of said devices with the purpose of cleaning hands or other body parts, e.g. armpits, and to apply ...
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IMPROVEMENTS IN OR RELATING TO A DEVICE FOR CLEANING TEETH

(WO2003020075) 13.03.2003 A46B 5/04 INTELLECT HIGHWAY LTD
A device for cleaning teeth, the device being adapted to be inserted in the mouth and chewed, the device comprising a core defining an axis, the core pivotally supporting two main flaps, the main flaps being located substantially in alignment with each other on opposed sides of the axis of the core, each said flap carrying a generally perpendicularly extending actuating member, the actuating member or members of each flap extending transversely of the core towards the other flap, the arrangement being such that, on chewing of the clement, teeth will engage the actuating elements causing the flaps to pivot inwardly towards the said teeth.
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STAIN REMOVING CHEWING GUM AND CONFECTIONERY COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME

(WO2003020047) 13.03.2003 A23G 3/00 CADBURY ADAMS USA LLC
A composition in the form of a chewing gum composition or a confectionery composition containing stain removing agent selected from anionic and non-ionic surfactants and methods of preparing and using the same to remove stains from dental material including teeth.
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SAFETY CAP AND CONTAINER WITH SAFETY CAP

(WO2003018422) 06.03.2003 B65D 47/08 YOSHINO KOGYOSHO CO., LTD.
A safety cap requiring skill with the hands for opening operation, hard to be opened by a child, and capable of releasing a safety function as required, wherein a part of the outer peripheral wall (11) of a cap body (2) is formed in an operating plate (6) elastically deformable inward, a pair of engaging means (7) and (22) engaged with each other are provided in the peripheral wall of the cover (2) hinged to the upper part of the cap body (2) and at the upper part of the operating plate (6) so that the cover can be opened by releasing the engagement by elastically deforming the operating plate inward, whereby, with the operating plate (6) deformed inward, the operating plate (6) can be fixed to a cap body (2) portion excluding the operating...
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PRIMARY MOLDED PRODUCT FOR BIAXIAL STRETCH BLOW MOLDED BOTTLE BODY, AND BOTTLE BODY

(WO2003018292) 06.03.2003 B29C 49/06 YOSHINO KOGYOSHO CO., LTD.
In a primary molded product for a biaxial stretch blow molded bottle body having a gas barrier material layer (3) laminated in a polyethylene terephthalate resin layer (2), the gas barrier material layer (3) extends at least from the upper portion of a neck ring (5), which is somewhere between the ends of a mouth (4) including a neck ring (5), to substantially the lower end of a trunk portion (6), the mean wall thickness of the gas barrier material layer (3) in the mouth (4) is not more than 1/3 of the greatest wall thickness of the gas barrier material layer (3) in the trunk portion (6), and the most of the used gas barrier material is positioned in the trunk portion (6), thereby making effective use of the gas barrier material. In the...
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ANTIMICROBIAL ORAL COMPOSITION AND METHOD OF USE

(WO2003017961) 06.03.2003 A61K 8/20 SASSON, Joseph, A.
This invention provides a liquid antimicrobial composition that is particularly useful as a mouthwash for treating or reducing the risk of dental disease. The composition is prepared by mixing a first solution comprising a water soluble metal chlorite compound with a second solution comprising a physiologically acceptable oxidizing agent capable of oxidizing chlorite to ClO2? and hydrogen peroxide. The resulting composition, containing chlorine dioxide, is preferably used at the time of preparation by applying the composition to the locus where treatment is desired.
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STABLE DENTAL ANALOG SYSTEMS

(WO2003017862) 06.03.2003 A61C 1/08 MAROTTA, Leonard
A stable dental prosthesis system includes transparent guides (240, 250, 260) with radio opaque markers (242, 262, 263) therein to accurately position an implant (220) in a jaw. To make the prosthesis for the implant (220), an implant analog (320, 420, 520, 620, 720) is used with an abutment (1020) that can be mounted in the dental lab replica of the relevant section of a patient's mouth securely. The analogs hava a pin (312, 2012) or other protrusion that projects from the base of the analog. The system also includes a perforated tray (2101) for accommodating protruding implant impression copings (2123) therethrough when the impression mold is made of the dental patient's mouth. A generally flat articulation wafer (2301) connects one impre...
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MEANS FOR DENTAL, MOUTH AND HAND HYGIENE AWAY FROM HOME

(WO2003017800) 06.03.2003 A46B 15/00 JANKOVCOV, Marie
The invention relates to means for dental, mouth and hand hygiene, away from home, for solving the problem of dental, mouth and hand hygiene after a meal, away from home, in any place where a person can be and where water, soap or clean hand towels are not available. The invention is characterised in that dental floss is packaged together with cleaning towels in a small package that a person can carry with him/her, anywhere and without any difficulty, in order to be readily available, and so that the person is able to clean his/her interproximate spaces after each meal and have his/her hands really clean before and after a meal. The invention allows a person to feel good, clean and sure of himself/herself, also in personal relations with ot...
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ONE-PART SELF-PRIMING DENTAL ADHESIVE

(WO2003013444) 20.02.2003 A61K 6/00 DENTSPLY INTERNATIONAL INC.
A dental adhesive composition for bonding dental restoratives to dentin and enamel provides a one-part self-etching, self-priming dental adhesive composition having hydrolysis stable polymerizable acidic adhesive monomers.
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MULTI-PART DENTAL BLEACHING SYSTEMS AND METHOD FOR BLEACHING TEETH USING SUCH SYSTEMS

(WO2003013380) 20.02.2003 A61K 8/22 ULTRADENT PRODUCTS, INC.
Dental bleaching systems that include a bleaching component and a neutralizing component which, when mixed together, yield a mixed composition having a desired bleaching activity and gel properties. The bleaching composition includes a suitable bleaching agent, such as aqueous hydrogen peroxide, in a concentration of about 3 % to about 95 % by weight of the bleaching composition component. The neutralizing component includes a strong particulate base mixed with a polymeric thickening agent. The neutralizing component is substantially water-free to prevent destruction of the gelling capability of the thickening agent by the base prior to formation of the mixed composition. The particulate base may include oxides, hydroxides or carbonates of ...
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DENTAL COMPOSITIONS

(WO2003013379) 20.02.2003 A61K 6/083 B.J.M. LABORATORIES LTD.
There are provided polymerizable compositions comprising at least one polymerizable monomer, a polymerization initiator, at least one filler, a polymerizable resin comprising a thermoplastic resin, and a dendritic molecule, wherein said composition contains at least about 40-95 wt.% of said filler, and from about 0.1 to about 10.0 wt.% of said dendritic molecule. Preferably, the dendritic molecule is a hyperbranched molecule which is a branched condensation polymer containing ester groups and at least one amide group in the polymer backbone, having at least one hydroxyalkyl amide end group,. Also provided are dental materials formed from such compositions.
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FIBREBOARD CONTAINER WITH PLASTIC CLOSURE

(WO2003011491) 13.02.2003 B21D 5/06 WELLER, David, Thomas
A beam is formed from a rectangular strip (11) of metal having Laser cut parallel longitudinal edges by, first, bending the strip (11), using a jig arrangement, about two fold lines respectively inset from the longitudinal edges (13A, 13b) of the strip (11), such as to create two upstanding marginal flanges. Next, the so-flanged sheet is bent about a longitudinal central fold line (35) such as to create a longitudinally-folded sheet of V-form cross-section, but with in-turned flanges at the mouth of the V-form section. Finally, the V-form folded sheet is braced using either a metal strip (39) or external constraint members that embrace the V-form folded sheet at intervals therealong. The beam may serve as a trackway means for a machine tool...
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ELECTRICAL FUMIGATION DEVICE

(WO2003011023) 13.02.2003 A01M 1/20 S. C. JOHNSON &SON, INC.
A fumigation device (10) is provided that is configured to be plugged into an electrical receptacle regardless of its orientation. A housing (12) has an axially extending member (16) with an outer end that is connected to a radially extending member (18). The radially extending member (18), in turn, has an outer end defining a delivery port (14) that directs gaseous fumigant away from the wall. A canister (22) is disposed within the housing (12) and defines a cavity having a mouth in communication with the delivery port (14), the cavity containing a heat-activatable fumigant (24). A heater (42) supplies heat to the canister (22) when an electrical plug (40) is inserted into the receptacle to activate the active chemical ingredient. A gel tr...
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PERIODONTAL REGENERATION COMPOSITION AND METHOD OF USING SAME

(WO2003010742) 06.02.2003 A61K 6/06 SZYMAITIS, Dennis, W.
A periodontal structure regeneration composition for treatment of periodontal disease is a mixture of particles of a bone growth material and free collagen. All particles are sized to be less than 1 mm in diameter. The periodontal regeneration composition is injected into the periodontal pocket through an 18 gauge needle. The composition is available in pre-filled syringes offered in a kit that may also contain strips of surgical sponge or gauze that are sized to fit within a periodontal pocket, a tube of adhesive, a dental bur, a probe, a gauze placement tool, gauze counter and a brush for cleaning the dental bur.
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APPARATUS AND METHODS FOR CLEANING AND CONTROLLING BACTERIA GROWTH IN FLUID SUPPLY LINES

(WO2003010094) 06.02.2003 A61L 2/03 H20 TECHNOLOGIES, LTD.
A two-component tooth whitening system which incorporates an increased peroxide content, wherein the components are adapted to be mixed and applied to the teeth from a dental bleaching tray is provided. A first component includes both carbamide peroxide and hydrogen peroxide and a second component comprises an orally compatible activator gel.
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FLATTENING AND GUSSETING DEVICED, METHOD AND BAG

(WO2003010056) 06.02.2003 B31B 19/36 NORFOLIER AS
An easy to open plastic film bag (1) provided with overlying front and rear walls (2, 3) joined by means of inwardly extending lateral gussets (5, 6) each constituted by two panels (7, 9 and 8, 10) having different widths such that the front and rear walls are laterally offset distances d1 and d2 to form two lateral strip-like zones (17, 18) between the lateral edges (15, 16) of the rear wall and the corresponding lateral edges (13, 14) of the front wall, said lateral zones being intended for being gripped and pulled away from one another to open the mouth of the bag.
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A METHOD AND SYSTEM FOR TOOTH WHITENING FOR LONG TERM EFFICACY

(WO2003007680) 30.01.2003 A61K 8/22 DEN-MAT CORPORATION
A method and system for whitening teeth using at least a whitening gel, a whitening toothpaste, and a whitening rinse. Preferably the system employs a predetermined weight percentage of a peroxide based bleaching agent to effect tooth whitening. In certain formulations the components may use carbamide peroxide or hydrogen peroxide as a bleaching agent. The system may be used at home and preferably does not require clinical visits. The method includes the steps of brushing the teeth daily and before each bleaching with a whitening toothpaste, bleaching the teeth with a whitening gel twice daily, and rinsing with a whitening rinse. Daily brushing with a whitening toothpaste and preferably rinsing with a whitening rinse follow these whitening ...
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DEVICE AND METHOD FOR CLEANING MOULD PADDLES

(WO2003006182) 23.01.2003 A61C 9/00 V.O.F. DEMATO
The invention relates to a device for cleaning dental trays (1) at least partly filled with a moulding material, comprising a container (7), means (9) for placing a cleaning liquid under pressure, and spraying means (15) for spraying the pressurized cleaning liquid into the container (7). The invention further comprises a method for cleaning dental trays (1) at least partly filled with a moulding material.
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A METHOD OF TREATMENT AND/OR PROPHYLAXIS OF ULCERS

(WO2003006072) 23.01.2003 A61K 31/194 PENAM INVESTMENTS PTY LTD
The present invention relates generally to a method for the treatment and/or prophylaxis of a condition involving one or more ulcers that affect the inside of the mouth and other mucous membranes. More particularly, the present invention is directed to a method for treating and/or reducing the likelihood of developing ulcers and particularly of the recurrence of recurrent ulcers. The present invention is particularly directed to a composition which promotes or enhances the healing of aphthous ulcers thereby reducing at least one of the symptoms of aphthous ulcers and/or the risk of developing one or more of said symptoms.
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METHOD AND DEVICE FOR RECOGNIZING DENTAL CARIES, PLAQUE, CONCREMENTS OR BACTERIAL ATTACKS

(WO2003005892) 23.01.2003 A61B 5/00 FERTON HOLDING SA
The invention relates to a method and a device for recognizing caries, plaque, concrements or bacterial attacks, wherein a radiation is generated with the aid of a light source. Said radiation is directed at a tooth to be examined and provokes a reflective radiation in said tooth. The reflective radiation is detected with a detecting device and then evaluated. The radiation is advantageously carried out with two or more spectral ranges, wherein the measured reflection intensities of the two spectral ranges are correlated as characteristic values indicating the existence of caries, plaque, concrements or bacterial attack. This can also be supported by evaluating fluorescence radiation.
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COMPOSITION WITH ENHANCE CETYLPYRIDINIUM CHLORIDE ACTIVITY AND METHOD OF USING THE SAME

(WO2003002056) 09.01.2003 A61K 8/41 CHURCH &DWIGHT CO., INC.
An oral composition comprises an antibacterial effective amount of cetylpyridinium chloride, an effective amount of guar hydroxypropyltrimonium chloride, sufficient to bind to compounds which undesirably bind to cetylpyridinium chloride thereby enabling the cetylpyridinium chloride to effectively bind to tooth surfaces and perform an antibacterial function, and an orally acceptable carrier.
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ORAL CARE COMPOSITIONS

(WO2003000217) 03.01.2003 A61K 8/25 THE PROCTER &GAMBLE COMPANY
Oral care compositions comprising unique silica abrasives and methods for polishing and cleaning dental enamel using these oral care compositions are disclosed.
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TOOTH-PASTE COMPOSITION HAVING ANTI-PLAQUE PROPERTIES

(WO2003000215) 03.01.2003 A61K 8/49 HERBARIORUM MEDICAMINUM OFFICINA ALTA BADIAE S.N.C.
Tooth-paste composition having the form of a paste of solid materials containing a small amount of water comprising : a) an abrasive agent to remove the protein film formed on the tooth surface, without any damaging of the tooth enamel. b) a preferably anionic surfactant agent to help the frothing and making more pleasant the use of tooth-paste ; c) gelating compounds restraining the tooth paste contained water from separating in order to insure a long time tooth paste softness. d) products capable of maintaining the abrasive agent within the suspension. e) one or more of the following additives : whitening agents, as peroxides or persalts, anti-caries agents i.e. fluorine derivatives ; f) one or more anti-plaque agents, consisting of anti-...
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Title Pub. Date Int. Class Applicant
MUCOSAL REPAIR BY TFF2 PEPTIDES

(WO2002102399) 27.12.2002 A61K 38/00 NOVO NORDISK A/S
The present invention relates to the use of trefoil factor 2 (TFF2) peptides and a pharmaceutical composition comprising TFF2 peptides for increasing the viscosity of mucin in mucus layers and the repair of damaged mucus layers in the gastrointestinal tract (mouth, oesophagus, stomach, small and large intestine, colon ) the respiratory passages, the eye, the urinary system (including the bladder) and the cervix uteri.
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LIQUID POLYMER COMPOSITION FOR PREVENTION AND TREATMENT OF THE ORAL CAVITY DISEASES

(WO2002098464) 12.12.2002 A61K 9/00 ITALMED S.N.C. DI GALLI G. &PACINI G.
A new composition for treating periodontal disease by means of a therapeutic agent delivery device placed within the periodontal pocket so that release of the therapeutic agents occurs in the immediate vicinity of the disease process, without that a release adjusting agent or adhesive agent is present so that biocompatibility or allergic problems cannot arise. A slow release of a therapeutic agent is obtained as well as a mechanical protection on the wounds and a barrier to bacteria. The a composition comprises a therapeutic agent in a biocompatible polymeric material. The therapeutic agent is soluble both in water and in alcohol and the biocompatible polymeric material is a liquid methacrylate copolymer chosen among EUDRAGIT RL or EUDRAGIT...
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FORMULATION COMPRISING MELT GRANULES OF NSAIDS AND ORGANIC ACIDS

(WO2002098387) 12.12.2002 A61K 9/00 THE BOOTS COMPANY PLC
A pharmaceutical formulation adapted to disintegrate in the mouth is described. The formulation comprises a low-melting non-steroidal anti-inflammatory drug and an organic acid and comprises: (a) a granular composition comprising a plurality of solidified melt granules of the non-steroidal anti-inflammatory drug; and (b) an organic acid.
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REMINERALIZING DENTAL HYGIENE PRODUCTS

(WO2002098383) 12.12.2002 A61K 8/24 CALCIO B.V.
The present invention relates to remineralizing dental hygiene products like tooth pastes, chewing gums, mouth rinsing fluids, saliva substitutes and gel suspensions. The present invention is characterized in that the remineralizing hygiene products comprises CaKPO4? and/or Ca2?Kna(PO4?)2?, or combinations of calcium ions, potassium ions, and phosphate ions, as well as the usual additives.
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DEVICE FOR APPLYING SUBSTANCES

(WO2002094369) 28.11.2002 A61N 1/30 NOVA TECHNICAL RESEARCH GMBH
The invention relates to a device for applying substances such as medicaments having a liquid, ointment or gel-like consistency through the skin, especially by means of iontophoresis. The resorption of the substance occurs by an electric field which can be generated between two electrodes (2) by a defined direct current. A capsular, hermetically sealed container (1) is provided, which can be inserted in body orifices, said container having at least two electrodes (2) for generating a continuos electric field on its outer side. A device (3) for receiving the substance to be applied is provided above the electrodes (2). The container (1) is arranged contacting the mucous membrane and/or the skin in a body orifice, especially in the urogenital...
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DENTAL RESTORATIVE MATERIALS

(WO2002094204) 28.11.2002 A61K 6/02 THE UNIVERSITY OF MELBOURNE
The present invention relates to a composition for dental restoration including a dental restorative material and an effective amount of a casein phosphopeptide(CPP)-amorphous calcium phosphate (ACP) complex or casein phosphopeptide(CPP)-amorphous calcium fluoride phosphate (ACFP) complex.
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DENTAL HYGIENE DEVICE

(WO2002094119) 28.11.2002 A61C 17/02 INIZIATIVA CENTRO SUD S.R.L.
The dental hygiene device comprises means for connecting it to a water tap and means for delivering the water in a way suitable for cleaning teeth, which comprises means for adjusting the pressure of the water capable of being associated with and disassociated from the connection means to deactivate and activate, respectively, static aeration means of the water operatively associated with the connection means.
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THICKENING PRECIPITATED SILICA GRANULES OBTAINED BY GRANULATION AND USE THEREOF AS THICKENING AGENT IN DENTAL COMPOSITION

(WO2002092509) 21.11.2002 C01B 33/193 RHODIA CHIMIE
The invention concerns thickening precipitated silica having a median diameter of at least 100 $g(m)m and cohesion factor FC of at least 0.3, obtained by wet process granulation of thickening precipitated silica, drying and optionally sieving, the granulation step being carried out in a low-shear granulation apparatus, using at least a precipitated silica powder (a), having a DOP of at least 230 ml/100g, a median diameter D50a? of at least 14 $g(m)m; particles of at least a precipitated silica (b) having a DOP of at least 230 ml/100g, a median diameter D50b? of at least 0.3 $g(m)m; and water (W) as binder, the dry extract of the mixture formed by the silicas (a) and (b) and water being between 25 and 40 wt. %, the weight ratio (a)/(b), ...
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TASTE MASKING PHARMACEUTICAL COMPOSITION

(WO2002092106) 21.11.2002 A61K 9/16 PACIFIC PHARMACEUTICALS LIMITED
The invention describes a composition suitable for oral administration comprising an antibiotic macrolide and a polycarbophil. The antibiotic macrolide is preferably clarithromycin. The polycarbophil is reported to have surprising taste-masking properties in combination with the antibiotic and acts by inhibiting the undesirable release of the antibiotic component in the mouth or stomach. Several methods of preparing granules of the antibiotic macrolide and polycarbophil are also described.
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METHODS FOR TREATING OR PREVENTING DISEASES OF THE ORAL CAVITY

(WO2002092039) 21.11.2002 A61K 8/64 CAMPINA MELKUNIE B.V.
The present invention relates to a method of reducing dental plaque and calculus deposition. The invention further relates to a method of treating or preventing periodonitis and other diseases of the teeth and tissues of the oral cavity. The invention further relates to compositions suitable for use in such methods.
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SELF-ADHESIVE DENTAL MATERIALS

(WO2002092021) 21.11.2002 A61K 6/00 3M ESPE AG
The invention relates to a composition which is self-adhesive to the hard tooth tissue, comprising: (A) 5 to 75 percent by weight of one or more mono or higher functional ethylenically unsaturated compounds which additionally have an acid functional group, wherein one of said compounds has a P-OH group, for instance a phosphoric, phosphonic or phosphinic acid group; (B) 2 to 50 percent by weight of one or more mono or higher functional ethylenically unsaturated compounds without any acid functional group; (C) 22.8 to 85 percent by weight of filling material(s), comprising at least one filling material that may react with component (A) in the sense of causing a ion exchange, neutralization, salt formation and/or chelate formation reaction; (...
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VACUUM GROOMING TOOL

(WO2002091818) 21.11.2002 A01K 13/00 HAIR PATROL LLC
A vacuum grooming tool is disclosed. The tool includes a vacuum nozzle that is attachable to a vacuum source and has a hollow body with a mouth opening and a grooming device spanning the mouth opening. The grooming device can be a variety of standard animal grooming hand tools, such as a shedding blade, comb, rake, brush and dematting tool. The grooming device is positioned relative to the mouth opening such that the air flow created by the vacuum source flows over both sides of the grooming device for more efficient hair removal. A vacuum cleaning tool for removing any animal hair stuck to a grooming tool is also disclosed. The cleaning tool has a vacuum plenum that can be attached to a vacuum source and has an opening wide enough to enabl...
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DENTAL COMPOSITION FOR TREATING HYPERSENSITIVE TEETH

(WO2002089690) 14.11.2002 A61K 8/55 BLOCK DRUG COMPANY, INC.
The present invention provides dental compositions and methods for treating dentinal hypersensitivity teeth with a composition containing anionic liposomes having the capacity to induce mineral formation in the dentinal tubules, partially or fully blocking the tubules. The subject compositions comprise the liposomes and a suitable carrier and are advantageous in that they can deliver additional agents useful in the treatment of dentinal hypersensitivity, particularly nerve desensitizing agents, to the tubules. The liposomes of the invention are further advantageous in that they are stable to conventional sources of fluoride ion conventionally used as anti-caries agents. The methods of the present invention utilize the subject composition to...
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LASER LIGHT LURE

(WO2002089568) 14.11.2002 A01K 75/02 WIGTON, Andrew
A laser light lure device comprises a laser light aquatic species as herein defined attractant or distractant device characterised in that the species is pre-selected for catching and/or distracting in that the wavelength of the laser light is selected to catch and/or distract the species concerned by forming inter alia a visible or humanly invisible (i.e. UV) continuous or discontinuous ring about the mouth of a fishing trawler net (not shown). Motor (44), angled ellipsoidal mirror (49), right angled mirrors (47), mirrors housing (59), pin (63), lasers (45, 46), spring (50), weight (56), motor spindle (48), bearings (60), housing (62), impact protection (58, 65), dowels (57), back-plate (61), self-levelling devices (51), fluid reservoir (5...
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SYSTEM AND METHOD FOR CLEANING HIGH LEVEL DISINFECTION, OR STERILIZATION OF MEDICAL OR DENTAL INSTRUMENTS OR DEVICES

(WO2002087635) 07.11.2002 A61B 1/12 ECOLAB INC.
The present invention includes a method and system (1) for cleaning, disinfecting, or sterilizing objects, such as medical or dental instruments or devices. The system (1) of the invention includes an energy source (5), such as a sonicator, adapted and configured to impact the object with energy, such as ultrasonic energy; a liquid transporter (7) adapted and configured to circulate around, through, and/or into the object a wash composition, an antimicrobial composition, a rinse composition, or a plurality of these compositions; and a dryer (9) adapted and configured to dry the object, preferably, in the presence of a sterilant. The method of the invention includes contacting the object with a wash composition and energy, such as ultrasonic...
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CONTAINER FOR CLEANING IMPLEMENTS, IN ADDITION TO AN INSERTION BODY, TOOTHBRUSH AND RESERVOIR

(WO2002087388) 07.11.2002 A46B 17/06 NEUFELD, Klaus
The invention relates to a container for cleaning implements, in particular for dental or oral hygiene implements such as toothbrushes, interdental brushes, dental floss or similar. A reservoir (5) containing a volatile antimicrobial substance in gaseous form is provided in or on the container (1). The invention also relates to an insertion body for a container, whereby the insertion body is configured as a reservoir (5), or contains the latter as an integral part. The reservoir contains an antimicrobial substance in gaseous form and the diffusion rate for the active substance is controlled by the substance in the reservoir, or by a casing that surrounds said reservoir substance. The invention also relates to a toothbrush comprising a reser...
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LIGHT-POLYMERIZABLE DENTAL COMPOSITION CONTAINING AN INHIBITOR

(WO2002085974) 31.10.2002 A61K 6/083 DENTSPLY INTERNATIONAL INC.
Light-polymerizable dental composition comprising (i) a polymerizable monomer component, (ii) a light-sensitive polymerization initiator, (iii) an inhibitor, (iv) optionally a filler and/or pigment, and (v) optionally a solvent, characterized in that the inhibitor is a substituted fullerene compound present in an amount suitable for improving light stability of the dental composition.
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FLUORIDE COMPATIBLE CALCIUM CARBONATE

(WO2002085319) 31.10.2002 A61K 8/19 SPECIALTY MINERALS (MICHIGAN) INC.
The invention relates to a composition having finely divided calcium carbonate particles treated with fatty acids or polysaccharides. The invention further relates to a method for the preparation of the composition and its use in applications where fluoride compatibility is desired. The method entails providing finely divided calcium carbonate particles, treating the particles with at least one of fatty acids or polysaccharides including gums, starches and/or mucilages, and adding the treated particles to a fluoride containing toothpaste formulation.
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DENTAL COMPOSITION

(WO2002085313) 31.10.2002 A61K 6/083 3M INNOVATIVE PROPERTIES COMPANY
The inventive dental composition comprises (a) a part A comprising at least one polyacid and at least one polymerizable component; and (b) a part B comprising water, wherein the composition further comprises an oxidizing agent, a reducing agent, and reactive fillers in at least one of part A or part B and wherein at least one of the polyacid, oxidizing agent, and reducing agent is in a disperse phase. The dental composition can be used in many dental applications and is particularly suited for use as a cement.
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VERTEX DENTAL MODEL ARTICULATOR

(WO2002085235) 31.10.2002 A61C 11/02 IVERSON, Corey, B.
An improved ball-and-socket joint for use with dental model articulators of a vertex type comprising two brackets (13,14) hinged together at one end and each connected at the other end by a ball-and-socket joint (11,12) to a separate one of two stone plates (21,22) bearing dental castings. The ball-and-socket (11,12) joints have releasable mechanical means (26)for affixing the ball in the socket after the plates have been aligned for bite and occlusal fit between the dental castings. Affixing the ball in a socket is achieved by mechanically adjusting the diameter of one relative to the other of the socket and the ball to create a friction force that affixes the ball in the socket. In one embodiment, the mechanical means comprises a C-clamp ...
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A DEVICE FOR CLEANING THEETH

(WO2002085154) 31.10.2002 A46B 7/06 KEAVENEY, Enda
A device for cleaning teeth is provided which is dimensioned to be inserted into the mouth and chewed. The device has a core, the upper and lower parts of the core each carrying bristles or inserts of cleaning or abrasive material. Parts of the core have cut-outs to permit the core to flex in at least one plane.
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STRUCTURE AND PROCESS FOR CONTINUOUSLY TREATING DENTAL UNIT WATER

(WO2002081378) 17.10.2002 A61C 1/00 DOWNS, Bradley, J.
The invention pertains generally to dental units (e.g., a high-speed dental handpiece (11), an ultrasonic scaler(13)and an air/water syringe(12)) connected to a water supply that provides coolant and rinse water to the dental units. More particularly the invention pertains to a dental unit using water that is continuously treated with a water treatment agent, such as microbiocidal silver ions. The treated dental unit water is supplied to the dental units via dental unit waterlines (6, 7, 8, 9, 10).
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KITS FOR WHITENING TEETH

(WO2002080873) 17.10.2002 A61C 5/00 THE PROCTER &GAMBLE COMPANY
A kit for whitening teeth is provided. The kit includes a package containing a tooth whitening composition with a peroxide active and instructions in association with the package for minimizing soft tissue irritation comprising an instruction not to brush the teeth and/or soft tissue prior to applying the tooth whitening composition.
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COMPOSITION FOR IMPROVING THE TASTE AND SWEETNESS PROFILE OF BEVERAGES HAVING INTENSE SWEETENERS

(WO2002080704) 17.10.2002 A23L 1/236 MICHIGAN BIOTECHNOLOGY INSTITUTE
A composition including: an intense sweetener, a gum; a food additive comprising an amino acid, selected from organic acids, inorganic acids and mixtures thereof, and a metal ion; and an agent that masks or blocks the taste of bitter substances is disclosed. The composition may be incorporated into a beverage (such as a carbonated soft drink and flavored water). The components in the composition other than the intense sweetener eliminate the off flavors due to the intense sweetener. The components in the composition other than the intense sweetener improve the shelf life, enhance the mouth-feel, eliminate the off flavors of the intense sweetener, and improves the time-intensity profile of a beverage or other oral use product.
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POLYMER-METAL COMPOSITION RETAINER FOR SELF-LUBRICATING BEARING

(WO2002079686) 10.10.2002 A61C 1/18 NEW HAMPSHIRE BALL BEARINGS, INC.
The retainer (20) of the present invention is made of a composite material having a body made from a polymer, a layer of solid lubricant formed over the body by chemically coating the body with a porous layer of solid lubricant and impregnating the solid lubricant with another lubricant using conventional methods such as vacuum impregnation. The retainer (20) is placed between an outer raceway (32) and an inner raceway (34) to form a self-lubricating bearing (30). The bearing (30) made in this manner has high lubrication tolerance (i.e. it performs well in the absence of external lubrication). Because of its high lubrication tolerance, the bearing is suitable for use in various applications such as dental/medical hand pieces that are period...
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REDUCTANT RINSE FOR USE WITH OZONE TREATMENT OF DENTAL CARRIES

(WO2002078663) 10.10.2002 A61K 7/16 CUROZONE IRELAND LIMITED
A reductant rinse including Xylitol prevents buildup in ozone carrying lines in apparatus for the treatment of dental carries.
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DENTAL COMPOSITIONS

(WO2002078646) 10.10.2002 A61K 6/00 PENTRON CORPORATION
Curable compositions comprising degradable macromonomers having one or more terminal acrylate or methacrylate functionality, a curing composition, a filler composition comprising bioactive particles of bioactive glass, bioactive glass-ceramics, calcium phosphates, calcium appetites, or mixtures thereof and optionally one or more polymerizable acrylate or methacrylate comonomers. Degradable macromonomers are manufactured from cyclic monomers with compounds having acrylate or methacrylate functionality. Depending on their use, the degradable macromonomer compositions further comprise one or more organic or inorganic fillers, including a calcium-based compound and/or a radiopacity-imparting agent. The compositions are particularly suitable for...
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DISPOSABLE IMPRESSION TRAYS FOR EDENTULOUS DENTAL RIDGES

(WO2002076324) 03.10.2002 A61C 9/00 MAYO, Louis, J.
A disposable dental impression tray for making impressions of edentulous dental arches with impressionable material is made of plastic or some other inexpensive material and includes a thin contoured plate (14) having a contour (16) approximating a section of an oral cavity of a mouth of which an impression is to be made. The plate (14) has a impression side (18) for holding impressionable material and an opposite backside (20). A reinforced edge (22) runs around at least a portion (23) or border (24) of the plate (14) and cross-bracing (26) extends along the backside (20). A handle (34) located at a front (36) of the plate (14) extends generally normal to and away from the backside (20) of the plate (14) and has a flat surface on a front a...
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HEADSET WITH ADJUSTABLE MICROPHONE BOOM

(WO2002076147) 26.09.2002 H04M 1/05 GN NETCOM A/S
A headset with an adjustable microphone boom (1) which can be adjusted to and from a position near the mouth of a user and is mounted in a housing (7) by a friction part (6) being coupled to a flexible friction coupling which is configured in a plate (9) in that co-operating plates (20, 21) are stamped out of the plate and are connected to the plate (9) by means of flexible arms (21, 27, 28, 32). The friction part (6) has a shaft (5) which can be accommodated in a bearing defined by recesses which are configured partly in the inside (8) of the housing (7) and partly in the pate (9). The microphone boom (1), the housing (7) and the plate (9) with friction coupling are held together by means of a locking ring (11). In this way a stable, adjus...
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ORAL CARE KITS AND COMPOSITIONS

(WO2002074274) 26.09.2002 A61K 8/19 THE PROCTER &GAMBLE COMPANY
An oral care composition comprises polybutene with a molecular weight of about 300 to about 3000 and an oral care active. The oral care composition may further comprise an oral care carrier. Kits comprising polybutene, a container and instructions for use or an applicator for applying the composition directly to the tooth surfaces are also disclosed. The polybutene component of the kits can further comprise an oral care active or an oral care carrier.
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DENTAL PROSTHESIS COMPRISING A SUCTION RETAINING DEVICE

(WO2002071969) 19.09.2002 A61C 13/24 PROTHESE GRIP AG
After the completion of a dental prosthesis, several suction retaining devices (5) are placed in an individually distributed manner on said dental prosthesis, which is comprised of an anatomically adapted shaped part (1) and teeth (2), depicted here for mandibles. The primary part of a suction retaining device (5) is a vacuum adhesion-retained plate (6) that adheres to the alveolar ridge (3). The multitude of suction retaining devices (5), which are distributed over the adhering surface, result in a comfortable seat and a good adherence.
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DISPOSEABLE TOOTHBRUSH WITH INBUILT TOOTHPASTE RESERVOIR

(WO2002071894) 19.09.2002 A46B 11/00 THOMPBELL HOLDINGS PTY. LTD.
A toothbrush assembly, comprising a tubular handle portion (3) to comprise a reservoir for the containment of toothpaste (4), an outwardly extending plunger (2), a brush head portion (5) housing a central conduit (6) and smaller outlet conduits (7), such that depressing the plunger (2) conveys toothpaste (4) through the central conduit (6) and outlet conduits (7) at the base of the bristles. A removable cap (1) slidably mounted on the handle portion (3), prevents unintentional depression of the plunger (2).
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ESSENTIAL OIL FROM.COLEUS FORSKOHLII, PRODUCTION PROCESS AND USE AS ANTIMICROBIAL AGENT

(WO2002070638) 12.09.2002 A61K 8/31 SABINSA CORPORATION
Process for isolating an essential oil composition from Coleus forskohlii which is used in compositions and methods for the treatment of skin infections and in the prevention and treatment of dental caries.
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CLEANSING COMPOSITIONS FOR ORAL CAVITY

(WO2002067883) 06.09.2002 A61Q 11/00 SUNSTAR INC.
It is intended to provide cleansing compositions for oral cavity which can be conveniently used as mouth cleanser, impart a feel in using and a cleansing effect comparable to toothbrushes, and exert a massaging effect on the gingiva; and a method of cleansing the inside of the oral cavity. The cleansing compositions for oral cavity is characterized by containing a gel, while the method of cleansing the inside of the oral cavity is characterized in that the gel is finely divided in the oral cavity during using.
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PROCESS FOR THE PREPARATION OF A POLYMERISABLE DENTAL COMPOSITION

(WO2002064102) 22.08.2002 A61K 6/093 DENTSPLY DETREY GMBH
A process for the preparation of a polymerisable dental composition comprising the steps of (a) preparing a liquid mixture comprising (i) 1 to 99% w/w of a hybrid monomer component containing at least one hybrid monomer compound having one hydrolysable siloxane group and at least one polymerisable organic moiety, and (ii) 99 to 1% w/w of a monomer component polymerisable with the polymerisable organic moiety of the hybrid monomer compounds; and (b) adding at least a stoichiometrically sufficient amount of water to the mixture to hydrolyse the hydrolysable siloxane group of the hybrid monomer compound and to form spherical polymerisable nanoparticles having an average particle size of from 1 to 100 nm dispersed in the monomer component, wher...
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DENTAL AND MEDICAL POLYMER COMPOSITES AND COMPOSITIONS

(WO2002062901) 15.08.2002 A61K 6/083 VALLITTU, Pekka
The invention relates to polymerisable multifunctional polymer composites and compositions, which are suitable for dental and medical applications, such as dental prostheses, filling materials, implants and the like. It also relates to a method for the manufacture of such polymerisable multifunctional polymer composites and compositions, and to the use of said multifunctional polymer composites and compositions in dental and medical applications. A multifunctional polymer composite or composition is manufactured from 30-99 wt% of a monomer mixture containing 30-99 wt% of a dendrimer or a combination of dendrimers and 1-70 wt% of a reactive solvent or a combination of reactive solvents, and 0.1-70 wt% of a nanofiller or a combination of nano...
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CLEANING LIQUID SPRAYING DEVICE FOR AUTOMOBILE WINDSHIELD WASHER JETS

(WO2002060589) 08.08.2002 B05B 1/08 FICO TRANSPAR, S.A.
The device comprises a washer jet body (4) and a spraying unit (3) that fans out the cleaning liquid, which can be coupled to one another thereby configuring an inlet chamber (33) that hydraulically communicates with a cleaning liquid line. The spraying unit (3) can rotate about its longitudinal axis and is comprised of a first spraying body (1) and a second spraying, which can be coupled to one another and which define two equal passages (24) communicating with the inlet chamber (33) and converging in an outlet chamber (25) having an outlet mouth (29) opposite an outlet opening (31) in the body of the washer jet body (4).
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ANTI-CARIOUS CANDIES AND CONFECTIONS

(WO2002058582) 01.08.2002 A23G 3/00 AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION
Candies and confectioneries containing non-toxic sparingly soluble calcium and phosphate compounds as additives, cause the release of calcium and phosphate ions into the oral cavity gradually and persistently for a period no less than five minutes. Released calcium phosphate ions diffuse into partially demineralized tooth enamel or dentin, leasing to remineralization and repair of caries lesions, dental plaque, open dentinal tubules and exposed dentin. Agents and methods for remineralization of teeth, for reducing or eradicating cariogenic challenge in plaque following sucrose intake for producing effective anticaries actions without the use of fluoride and for desensitizing hypersensitive teeth are disclosed.
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IMPROVED TOOTHBRUSH

(WO2002058508) 01.08.2002 A46B 11/00 CALLIGARO, Vanni
A toothbrush (10; 100; 200; 300) that includes a head (12; 312) supporting a set of bristles (13), a handle (11; 311) joint to the head (12; 312), a chamber (14; 114; 214; 314) made inside the head (12; 312) and/or inside the handle (11) and containing a dentifrice substance (30), at least one duct (22, 122, 222, 322) that communicates said chamber with the external face of the head (12; 312) supporting the set of bristles, and control means acting inside the chamber to push the dentifrice substance (30) so as to cause its discharge from the ducts to impregnate the set of bristles (13).
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TOOTHBRUSH WITH GUIDE SPACE

(WO2002058507) 01.08.2002 A46B 9/04 LECLERCQ, Patrice
The invention relates to a toothbrush comprising bristles disposed in such a way as to create a guide space (E) which, during brushing, ensures that the bristles are kept in close contact with the anatomy of the teeth. Guide bristles delimit the guide space and are disposed in a V-shape with a truncated point so that they are ideally positioned in the dental plaque retention areas. The guide bristles are vertical or angular and are at least 3mm taller than the bristles disposed inside the guide space (E). In the case of brushes with bristles that are disposed outside the guide space (E), the height of said bristles can be smaller than or equal to that of the guide bristles so as to reinforce the action of the guide bristles .
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TOOTH WHITENING MATERIAL AND METHOD OF WHITENING TEETH

(WO2002058460) 01.08.2002 A61K 6/00 DENTSPLY INTERNATIONAL INC.
A dental tooth whitening material sets to a rubber-like or elastomeric consistency. The material includes hydrogen peroxide. A method of whitening teeth employs such a material by placing it into a dental tray, a backing sheet or by placing the material directly onto a tooth. Once the material has set to its solid or semi-solid consistency, the dental tray, if employed, can be left in place or removed.
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DUAL COMPONENT DENTIFRICE FOR REDUCING MOUTH ODORS

(WO2002053116) 11.07.2002 A61K 8/20 COLGATE-PALMOLIVE COMPANY
A dual component oral composition to suppress oral malodor and provide long lasting breath protection in the oral cavity which comprises a first dentifrice component having a substantially neutral pH and containing a zinc ion releasable compound and a chlorite ion releasable compound, the second dentifrice component having an acid pH, the first and second components being maintained separate from each other until dispensed and combined for application to teeth, the combined components having a pH of no greater than 7.
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DENTAL MATERIALS

(WO2002053107) 11.07.2002 A61K 6/083 3M INNOVATIVE PROPERTIES COMPANY
A dental composition is provided comprising: a part A comprising fluoroaluminosilicate glass that has been surface treated with agents selected from the group consisting of silane, silanol and combinations thereof, and at least one fatty acid; and a part B comprising at least one polyacid. The composition further comprises resin that can be curable or non-curable and at least one initiator. The composition exhibits adhesion to dentin, and the treated FAS glass contained therein does not settle out with time.
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PORTABLE MULTI-USING ONE-BODY-TYPE ARTICLE EQUIPPING A TOOTHBRUSH ETC. BY SET

(WO2002053051) 11.07.2002 A46B 15/00 JANG, Keum, Hwan
The present invention relates' a portable multi-using one-body-type article equipped with a toothbrush or similar' comprising an existing portable toothbrush (FIG1) and a toothpaste, a writing material and/or a compact combination gimlet and needle, in addition, including even a finger-pressure stick and fixture pin functional part by applying it on an outer surface of an overall cap of the article covered with any adhesive cloth such as a rough side of Velcro cloth (as a hook side) to maximize convenience and availability of the same. The article according to the present invention accomplishes varied uses and functions by comprising such integrated parts.
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TAPE CASSETTE

(WO2002052563) 04.07.2002 G11B 23/087 SONY CORPORATION
A tape cassette comprising a front lid (5) on the front side of a cassette housing (1), and a shutter plate (6) interlocked with an operation for opening the front lid (5) and retracting a mouth to slide back and forth on the upper surface of the cassette housing (1) wherein the side of the shutter plate (6) opposite to the front lid (5) and the side of the cassette housing abutting against that side are curved and the upward motion passage of the shutter is snaked so that a rectangular indication label (8) is not contained in the moving passage of the shutter plate (6), i.e. on the upper surface of the cassette housing (1).
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NANOPARTICULATE SURFACE-MODIFIED TITANIUM DIOXIDE AND THE USE THEREOF IN DENTAL CARE AGENTS

(WO2002051945) 04.07.2002 A61K 8/29 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to a nanoparticulate titanium dioxide with an average particle diameter ranging from 10 to 1000 nm, the particles being coated with a polar organic surface-modifying agent, preferably a phosponic acid. The inventive particles adhere well to dental surfaces and are suitable as tooth-brightening agents in dental cleaning and/or care compositions.
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DENTAL COMPOSITION BASED ON A FUNCTIONALISED SILICONE CROSSLINKABLE AND/OR POLYMERISABLE BY HEAT-PROCESS

(WO2002051357) 04.07.2002 A61K 6/093 RHODIA CHIMIE
The invention concerns dental compositions based on functionalised silicone crosslinkable and/or polymerisable by heat process, and useful for producing dental prosthesis, artificial teeth and dental restoration material. The dental compositions comprise at least a silicone crosslinkable and/or polymerisable oligomer or polymer, dental fillers, and an initiator capable of being thermally activated comprising a boron derivative of formula (A)x?B(R')y?.
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A DENTAL FLOSSING DEVICE

(WO2002051330) 04.07.2002 A61C 15/04 GUO, Chongwei
The present invention relates to tooth cleaning tool, especially, relates to a dental flossing tool using dental floss to clean tooth. The handle of the present invention is composed of a cavity handle body having a lead riser and a handle cover connecting to the port of the handle body. The said handle body has longitudinal sliding groove..The two sides of pushing handle of locking wire are slidingly engaged to the sliding groove. A spool of dental floss are provided lengthways in the handle, whose circular front baffle supporting on the convex table in the handle body, the axis center fosse of rear baffle engaging to the gimlet-point of supporting axis of handle cover. The arranges a retainer having thread hole on the bottom surface of th...
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NON-HALOGENATED PHENYL SUBSTITUTED PHENOLS, ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME

(WO2002050002) 27.06.2002 A01N 31/06 WARNER-LAMBERT COMPANY LLC
An antimicrobial compound of formulas (Ia), (Ib) or (Ic), compositions containing the same, and method of using the same for reducing the presence of microorganism on a substrate or in a fluid environment comprising an antimicrobial effective carrier and at least one antimicrobial compounds including non-halogenated phenyl substituted phenol compounds; wherein R1? and R2? are each independently selected from the group consisting of hydrogen, an alkyl group optionally substituted with a cycloalkyl group, a hydroxyl group, or an aryl group; an alkenyl group; an alkoxy group; a cycloalkenyl group; an aryl group; benzyl optionally substituted with an alkyl group; and a cycloalkyl group wherein any one of which said groups can optionally be ...
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DENTIFRICE PRODUCT

(WO2002049588) 27.06.2002 A61K 8/39 SOCIEDAD LIMITADA PARA EL DESARROLLO CIENTIFICO APLICADO
Comprises a surfactant, a cellulose derivative, additives and at least one resin charged with Ca?+2, F?-, PO4??3 oZn?+2 cations or anions, with the calcium, fluoride and phosphate ions in a molar ratio of 2:1:1 and the zinc ions in dry-weight proportion with respect to the resin or resins of between 0.5 and 2 %. It is used as a dental-tissue remineralising agent or for making a medicine for the treatment of buccal diseases and, in particular, for the treatment of caries.
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ORAL BLEACHING COMPOSITION

(WO2002047638) 20.06.2002 A61K 7/20 UNILEVER N.V.
The present invention relates to oral care compositions with an improved teeth whitening effect. This effect is achieved by inclusion in the oral care compositions of certain peroxyamido-phthalamides as teeth whitening/bleaching agents, together with hydrogen peroxide.
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ORAL COMPOSITIONS AND USE THEREOF

(WO2002047615) 20.06.2002 A61K 8/02 UNIVERSITY OF ROCHESTER
The present invention relates to an oral composition which includes an organoleptically suitable carrier and an amount of a terpenoid and a flavonoid, dispersed in the carrier, which is effective to prevent or treat dental caries, dental plaque formation, gingivitis, candidiasis, dental stomatitis, aphthous ulceration, or fungal infection. The invention also relates to various uses of oral compositions, containing a terpenoid, a flavonoid, or both, such uses include: inhibiting the activity of surface-bound glusosyltransferase; treating or inhibiting dental caries, gingivitis, candidiasis, denture stomatitis; inhibiting the accumulation of microorganisms on an oral surface; and/or treating or inhibiting aphthous ulcerations on an oral surfa...
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ENDODONTIC SEALING COMPOSITIONS AND METHODS FOR USING SUCH COMPOSITIONS

(WO2002047572) 20.06.2002 A61C 5/04 ULTRADENT PRODUCTS, INC.
Endodontic sealant compositions and methods for sealing a root canal (12) using sealant (30) or other filling materials. The compositions include one or more resins that promote adhesion to hydrophilic dental tissues. Examples include alkyl methacrylates and derivatives thereof, such as alkylamino methacrylates and oxyphosphoro methacrylates. The compositions include a radio opacifying agent, so that they may be seen using X-rays, and one or more polymerization initiators to effect curing, typically both chemical and photo initiators to yield a dual cure sealant composition. The compositions are introduced into the root canal (12) using a narrow cannula (26-Fig.2) coupled to a high pressure hydraulic delivery (24-Fig.2). Additional pressure...
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APPARATUS AND SYSTEM FOR STIMULATING MOUTH MUSCLES

(WO2002047538) 20.06.2002 A61B 17/00 MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
An apparatus and system for inducing stimulation of muscles within the mouth. The apparatus includes a housing (12) having a controller (17). A muscular contact member (14) extends from the housing and is configured to contact muscles within the mouth, including for example the palate and the tongue. A vibrating device (23) cooperates with the controller and muscular contact member to transmit vibration to the muscular contact member and in turn to muscles within the mouth. In the system, such an apparatus is provided that is rechargeable. A storage base receives the rechargeable apparatus when it is not in use and includes a battery charger. The storage base also optionally includes disinfecting means for cleaning the muscular contact memb...
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CHISEL SCABBARD

(WO2002045922) 13.06.2002 B24D 15/06 RECORD TOOLS LIMITED
A chisel scabbard (10) comprises a pouch (12) and a belt clip (22). An insert (14) is received in the mouth (16) of the pouch (12) and is adapted to receive various sizes of chisel. A flat front surface (64) is provided with abrasion material to permit sharpening of the chisel. Clip-means (50) enable two scabbards to be connected together by insertion of the clip-means (50) into a female clip receptor (52) on the front of the scabbard. A sharpener (90) is provided comprising an abrasion plate (110) mounted in a slider (100). The chisel displaces the plate in the slider on insertion of the chisel in the scabbard. The slider can be actuated to repeat the sharpening stroke. The pouch (12) can comprise two extruded sections (92, 94) and end cap...
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RAPIDLY DISPERSING PHARMACEUTICAL COMPOSITION COMPRISING EFFERVESCENT AGENTS

(WO2002045684) 13.06.2002 A61K 9/46 PHARMACIA CORPORATION
A novel method is provided for enhancing dispersion of drug-containing particles in an aqueous medium. According to this method, a solid dosage form of the drug is provided having incorporated therein a dispersion-enhancing amount of an effervescent agent wherein (a) the dosage form is adapted for swallowing without prior disintegration in water or in the mouth, and (b) the amount of the effervescent agent is not sufficient to substantially enhance disintegration of the dosage form in the aqueous medium.
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DESENSITIZING DUAL COMPONENT DENTIFRICE

(WO2002045679) 13.06.2002 A61K 8/19 COLGATE-PALMOLIVE COMPANY
A two component dental composition is disclosed which eliminates or substantially reduces the discomfort and pain associated with dentinal hypersensitivity which composition comprises a first dentifrice component having an alkaline pH and contains a potassium ion releasable compound and an alkali metal silicate, a second dentifrice component having an acid pH, the first and second components being maintained separate from each other until dispensed and combined for application to teeth requiring relief from dentine hypersensitivity, whereby heightened desensitization is experienced by the user.
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ANTI CALCULUS AND PLAQUE TOOTHPASTE COMPOSITION

(WO2002045677) 13.06.2002 A61K 8/22 LG HOUSEHOLD &HEALTH CARE LTD.
The present invention relates to a toothpaste composition for preventing calculus formation and removing plaque, more specificallyto the toothpaste composition comprising soluble ultra phosphate with network structure and zeolite granule. The composition of the present invention has superior effect to prevent and remove calculus, and removing interdental plaque.
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ADHESIVE COMPOSITIONS FOR BACK-COATING DENTAL PLATE AND HARDENING COMPOSITIONS FOR DENTAL USE

(WO2002045660) 13.06.2002 A61K 6/00 TOKUYAMA CORPORATION
Adhesive compositions for back-coating dental plate which comprise a halogen-free organic solvent such as ethyl acetate, ethyl formate or acetone, a polymer such as a methyl methacrylate-ethyl methacrylate copolymer, and a radical-polymerizable monomer such as tetramethylolmethane tetramethacrylate; and hardening compositions which comprise a radical-polymerizable monomer, an organic peroxide such as benzoyl peroxide, a tertiary amine compound such as diethyl-p-toluidine or dipropyl-p-toluidine and a hydroxycarboxylic acid such as malic acid or citric acid. The above adhesive compositions are free from halogen-containing organic solvent which is pointed out as being toxic, have sufficient adhesive properties and favorable handling propertie...
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MULTICOMPONENT BIODEGRADABLE BIOADHESIVE CONTROLLED RELEASE SYSTEM FOR ORAL CARE PRODUCTS

(WO2002045575) 13.06.2002 A23G 1/00 SALVONA L.L.C.
The present invention relates to a controlled release system of biologically active ingredients or sensory markers to the oral cavity and mucous membranes of various tissues. Preferably, the controlled release system comprises a biologically active agent or sensory marker incorporated into substantially solid nano-particles encapsulated in moisture sensitive micro-particles. The nano-particles have a hydrophobic core and a positively charged surface. The positively charged surface is formed by a cationic surfactant that is entrapped and fixed to the particle's surface as showed in Fig. 1.
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DISPENSER PUMPS

(WO2002043875) 06.06.2002 B05B 11/00 RIEKE PACKAGING SYSTEMS LIMITED
A dispenser pump e.g. for toothpaste has a plunger (21) connected to a proximal end of an elongate flexible plastics strip (22) which is run slidably along a guide track built into the discharge nozzle (14) of the pump alongside the discharge channel (63). The distal end of the guide track defines a bend which opens through a lateral slot into the discharge channel (63) just inside its external opening. Action of the plunger causes the strip (22) to slide back and forth along the track and round the bend, so that the tip of the strip is moved out of the mouth of the nozzle during dispensing but returns to block it and cut away residual product when the plunger is released.
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DENTAL ADHESIVE COMPOSITION

(WO2002043669) 06.06.2002 A61K 6/00 TOKUYAMA DENTAL CORPORATION
A dental adhesive composition comprising (A) a polymerizable monomer component containing a polymerizable monomer having an acid group, e.g., 11-methacryloyloxy -1,1-undecanedicarboxylic acid, (B) a mixed filler composed of a globular filler made of substantially noncrosslinked polymethyl methacrylate and a globular filler made of substantially noncrosslinked polyethyl methacrylate, and (C) a polymerization initiator; and a dental adhesive kit being a combination of the adhesive composition and a dental primer containing (D) a polymerizable monomer having an acid group, (E) an aryl borate compound, (F) an organic sulfinic acid salt, and (G) water. The dental adhesive composition has excellent workability and high adhesion performance.
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DENTAL ETCH WITH IMPROVED FLAVOR

(WO2002041863) 30.05.2002 A61K 6/00 VERHAVE, Michelle
An acid dental etch having improved taste, which comprises an acid in an amount effective to etch a surface of a tooth; a flavoring formulation that improves the flavor of the dental etch and is stable in the acid, in an amount that is effective in improving the flavor of the dental etch; and preferably, sufficient gelling agent to form a gel.
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APPARATUS, METHOD AND PRODUCT FOR TREATING TEETH

(WO2002041802) 30.05.2002 A61C 17/20 THE PROCTER &GAMBLE COMPANY
A brushing system including a multiple cartridge dispensing system which dispenses the treatment material either directly onto brush bristles, or through the brush to the bristles. A multiplicity of materials may be provided to the cartridges for use in brushing. In addition to use in dental care, the system finds utility in hair coloring, spot laundry cleaning, skin and nail care, and polishing, as well as numerous others.
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BIODEGRADABLE BIOADHESIVE CONTROLLED RELEASE SYSTEM OF NANO-PARTICLES FOR ORAL CARE PRODUCTS

(WO2002041765) 30.05.2002 A61K 9/00 SALVONA L.L.C.
The present invention relates to a controlled release system useful for site specific delivery of biologically active ingredients or sensory markers, over an extended period of time, targeting biological surfaces comprising the oral cavity and mucous membranes of various tissues, as well as the controlled release of the biological active ingredients or sensory markers. The controlled release system of the present invention is a nano-particle, having an average particle diameter of from about 0.01 microns to about 10 microns, which comprises a biodegradable solid hydrophobic core and a bioadhesive/mucoadhesive positively charged surface. The invention also relates to the use of the nano-particles of the present invention in consumer only hyg...
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METHOD FOR CLOSING AN OPEN-MOUTH BAG FILLED WITH A POWDERY MATERIAL AND INSTALLATION FOR IMPLEMENTING SAID METHOD

(WO2002038446) 16.05.2002 B65B 51/06 CIF
The invention concerns a method for closing an open-mouth bag filled with a powdery or granular material and an installation for implementing said method. The invention concerns a method and an installation for closing open-mouth bags filled with powdery or granular material so as to obtain a substantially parallelepiped closed bag. The installation comprises: at least a driving device (2) having at least a slide (3) for squeezing the mouth of the bag so as to define a closure zone, means (15) for spacing apart the flanks of the closure zone; means (9) for laying flat the flanks of the closure zone; means (13) for folding on each other the flanks of the closure zone; and means (10) for setting on the folded flanks at least a sealing adhesiv...
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LIQUID DELIVERY DEVICE

(WO2002036895) 10.05.2002 E03D 9/03 JEYES GROUP LIMITED
A liquid delivery device is particularly suited for dosing a toilet bowl with a viscous cleaning agent. Liquid from a reservoir (10) flows through a neck (52) into a cup (18) until the liquid levle reaches the mouth (54) of the neck (52). The space (14) in cup (18) is open to atmosphere. Liquid is draw from the cup (18) by a capillary (66) formed between the wall of cup (18) and an insert (60) and delivered on the surface (72) of a textile layer (6). Flush water runs over textile layer (6) to carry the liquid into a toilet bowl.
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ORAL PREPARATION CONTAINING SEAWEED FOR REDUCTION OF PLAQUE AND CALCULUS

(WO2002034279) 02.05.2002 A61K 6/00 SDC SWEDENCARE AB
An oral preparation for reduction of mammalian, e.g. human, cat or dog, plaque and/or calculus, such as bacterial plaque, arteriosclerotic plaque, atherosclerotic plaque, pleural plaque, dental calculus, renal calculus, biliary calculus, and prostatic calculus, contains a Ascophyllum sp., especially A. nodosum, seaweed or an extract thereof. The oral preparation is suitable for use in prophylactic and/or therapeutic method of treating plaque and/or calculus in a mammalian individual.
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DENTAL CARE COMPOSITIONS

(WO2002034221) 02.05.2002 A61K 6/02 THE PROCTER &GAMBLE COMPANY
The present invention relates to non volatile compositions that comprises: i) from about 0.5 % to about 60 % by weight, of a silicone resin; ii) from about 0.1 % to about 30 %, by weight, of a silicon gum; iii) from about 0.1 % to about 95 %, by weight, of a non volatile polysiloxane fluid which has a viscosity from about 1cStk to about 1000cStk; and from about 0.01 % to about 50 %, by weight, of an oral care active selected from teeth colour modifying substances, anti-tartar agents, anti-plawue agents, fluoride ion sources, anti-microbial agents, nutrients, antioxidants, H-2 antagonists, analgesics, anti-viral agents, mucosally absorbed pharmacological agents and mixtures thereof. A second aspect of the present invention relates to the use...
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DENTAL MATERIAL AND COMPOSITION

(WO2002034207) 02.05.2002 A61K 6/083 SUN MEDICAL CO., LTD.
A dental material containing a sulfur-bearing unsaturated carboxylic acid ester compound which bears both a sulfur -containing substituent and at least two (meth)acrylic acid residues bonded to secondary or tertiary carbon atoms through oxygen, more specifically, a dental material containing a polymerizable monomer represented by the general formula (1): (1) [wherein R11? is a divalent organic group; X11? is oxygen, sulfur, -COOH-, or (CH2?)q?X12?- (wherein X12? is oxygen or sulfur; and q is an integer of 1 to 3); R12? is hydrogen or alkyl; R13? is a sulfur-containing substituent; and R14? is hydrogen or methyl]. The dental material and dental compositions containing the same are excellent in X-ray opacity, transparency, c...
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ORAL COMPOSITIONS FOR REDUCING MOUTH ODORS

(WO2002032388) 25.04.2002 A61K 8/37 COLGATE-PALMOLIVE COMPANY
A method to suppress oral malodor and provide long lasting breath protection wherein there is applied to the oral cavity of the user an oral composition comprising an orally acceptable vehicle containing therein a flavor system comprised of a mixture of an essential oil and a coolant compound which is a menthyl ester of naturally occurring hydrocarboxylic acids having 2 to 6 carbon atoms esterified with C1?-C4? alkyl groups.
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USE OF OLIVE OIL IN THE PREPARATION OF A PRODUCT FOR ORAL HYGIENE FOR ELIMINATING OR REDUCING BACTERIAL PLAQUE AND/OR BACTERIA IN THE MOUTH

(WO2002032387) 25.04.2002 A61K 8/92 BIOCOSMETICS, S.L.
The invention relates to the use of olive oil in the preparation of a product for oral hygiene, for instance a toothpaste, a mouthwash, a mouth spray or inhaler or a chewing gum, to eliminate or reduce bacterial plaque and/or bacteria in the mouth, thereby achieving a reduction in the appearance of dental diseases (caries, periodontal disease) and halitosis.
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SYSTEM TO PREVENT SNORING

(WO2002032350) 25.04.2002 A61F 5/56 SNCHEZ PUEYO, Lourdes
The invention relates to a system to prevent snoring that can be used for people who snore and that comprises a slightly elastic strip (1) whose width is smaller than the mouth. The central area (2) on one of the sides of said strip has a lip protector and an adhesive is located on the two ends (3) thereof. The outer part of the strip is placed in a central, vertical position relative to the mouth of the user. The strip adheres to the furrow between the lips and the mentolabial groove, the central area (2) of the strip (1) being located between the front edge of both lips.
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DENTAL IMPRESSION MATERIAL UTILIZING RUTHENIUM CATALYST

(WO2002032338) 25.04.2002 A61K 6/10 KERR CORPORATION
A composition for use as a dental impression material including a polymerizable telechelic oligomer or polymer curable by ring-opening metathesis polymerization, a filler system, and a ruthenium carbene complex catalyst, whereby the catalyst initiates ring-opening metathesis polymerization of the composition. The invention includes a paste/paste system in which a base paste includes the polymerizable telechelic oligomer or polymer and a filler system and in which a catalyst paste includes the catalyst dissolved in an inert solvent and a filler system. The telechelic oligomer or polymer may be, for example, a polydimethylsiloxane end-functionalized with norbornyl groups. The catalyst may be, for example, a ruthenium carbene complex with a li...
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DENTAL COMPOSITIONS FOR HYPERSENSITIVE TEETH

(WO2002030380) 18.04.2002 A61K 6/00 BLOCK DRUG COMPANY, INC.
A composition for the treatment of sensitive teeth comprising a desensitizing amount of: a substrate treated with a desensitizing agent, wherein substrate acts as a delivery vehicle of therapeutic agents for the treatment of hypersensitive teeth and said desensitizing agent is coated or adsorbed on the surface or attached to the surface of the substrate by chemical, electrostatic or ionic bonds; and/or b) encapsulated or impregnated within the substrate.
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SURFACTANT SYSTEM FOR INCREASING DENTAL TISSUE ANTIBACTERIAL AGENT UPTAKE

(WO2002030379) 18.04.2002 A61K 8/34 COLGATE-PALMOLIVE COMPANY
An oral composition comprising in an orally acceptable vehicle, an effective antiplaque amount of an halogenated diphenyl ether or phenolic antibacterial compound, and an amount of an mixed anionic/zwitterionic surfactant system which is effective to increase the uptake of the antibacterial compound to dental tissue so as to enhance the therapeutic efficacy of the administered antibacterial compound.
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PRODUCT FOR CLEANING TEETH AND/OR THE MOUTH

(WO2002030377) 18.04.2002 A61K 9/00 CROISSANT, Karen
The invention relates to a product for cleaning teeth and/or the mouth, e.g. in the form of a paste, cream or gel for teeth. The field of application and/or range of action of said product is enlarged due to the fact that it contains at least one active ingredient in the form of a psychotropic agent, in addition to the standard constituents thereof. One such active ingredient can especially have a moderating, calming or stimulating effect on the psyche of the user of the product. The invention also relates to a second product for cleaning teeth and/or the mouth, e.g. in the form of a paste, cream or gel for teeth. The field of application and/or range of action of said second product is enlarged due to the fact that it contains at least one...
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DENTAL CLEANING AGENTS

(WO2002030376) 18.04.2002 A61K 8/44 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to aqueous dental cleaning agents consisting of particulate polishing agent components, humectants and surfactants. The surfactants contain a combination of anionic surfactants (A), non-ionic surfactants (N) and vegetable protein hydrolysates or their fatty acid (C12?-C22?) condensates. The anionic and non-ionic surfactants are preferably present in the weight ratio (A): (N) = 1: (0.2-2.0) and in a quantity of (A+N) = 1-3 wt.- %, in relation to the total weight of the dental cleaning agent, the protein hydrolysates or their fatty acid condensates in a quantity of 0.5-2.0 wt.- %, in relation to the total weight of the dental cleaning agent and in addition a betaine tenside in a quantity of 0.1-1.0 wt.- %, in relatio...
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FACIAL ANIMATION OF A PERSONALIZED 3-D FACE MODEL USING A CONTROL MESH

(WO2002030171) 18.04.2002 G06T 17/20 ERDEM, Tanju A.
A method for generating a 3-D model of a person's face is disclosed. The 3-D face model carries both the geometry (shape) and the texture (color) characteristics of the person's face. The shape of the face model is represented via a 3-D triangular mesh (geometry mesh), while the texture of the face model is represented via a 2-D composite image (texture image). The geometry mesh is obtained by deforming a predefined standard 3-D triangular mesh based on the dimensions and relative positions of the person's facial features, such as eyes, nose, ears, lips, chin, etc. The texture image is obtained by compositing a set of 2-D images of the person's face which are taken from particular directions such as front, right, left, etc. and modifying th...
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APPARATUS FOR CLEANING THE SURFACE OF A SLOW SAND FILTER IN A FILTERBASIN OF A WATER TREATMENT PLANT

(WO2002028504) 11.04.2002 B01D 24/20 JANKOVIC, Miodrag
The invention relates to a bottom suction assembly for surface cleaning of the sand bed in a slow filter in a filter basin of a water treatment plant. The assembly is constituted by a float craft (1) which is movable in the basin and has an elongate suction nozzle (3) extending transversely across the float craft and being vertically adjustable to a predetermined depth in the sand bed and also including a sieve (5), arranged at its mouth, and a vibrator (6) mounted on the suction nozzle (3) in order to generate vibrations in the sieve (5) so as to separate algae an other contaminations which are at the same time sucked up through the nozzle by a pump (8), connected thereto, and are then transported to a filter bag (15) supported by the floa...
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ORAL DEVICES

(WO2002028221) 11.04.2002 C08F 210/02 GILLETTE CANADA COMPANY
An oral device is provided that includes a handle, a head, extending from the handle and having a pair of elongated arms that include opposed surfaces; and a pair of opposed cleaning elements, mounted on the opposed surfaces, the cleaning elements being constructed and positioned to be inserted into the interproximal regions of a user's mouth when the oral device is moved back and forth over the user's teeth. Each of the cleaning elements are positioned at an acute angle with respect to an interproximal line defined through the interproximal region.
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RECLOSABLE PACKAGE AND CLOSURE STRIP

(WO2002026579) 04.04.2002 B31B 19/90 VELCRO INDUSTRIES B.V.
A reclosable package (10, 30, 40, 50) includes a pouch of flexible material (12) defining a pocket with an openable mouth, and a reclosable, resealable, resealable closure attached to the flexible material and positioned to secure and seal the mouth of the pocket. The closure includes opposing, parallel strips (18a, 18b) of foam material (402) secured to respective portions of the flexible material and having outer faces arranged to engage one another when the mouth of the pocket is in a closed state. The outer faces of the foam strips each carry an exposed, self-adhesive layer (406) for securing and sealing the mouth of the pocket in its closed state. Such closures are also provided in strip form, and methods of making bags having such clo...
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DENTAL CLEANING AGENTS

(WO2002026203) 04.04.2002 A61K 8/39 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to aqueous dental cleaning agents containing particulate polishing agent components, humectants and tensides, the tensides being in the form of a combination of anionic tensides (A), betaine tensides (B) and ethoxylated fatty acid-polyol monoesters (C). The inventive cleaning agents have particularly good foaming characteristics during teeth cleaning if the tenside components are present according to the weight ratio (A): (B): (C) = 1: (0.1-1): (0.5 -2) and in a quantity of (A+B+C) = 2-5 wt. % in relation to the overall weight of the dental cleaning agent. The ethoxylated fatty acid-polyol monoester is preferably a polyoxyethylene sorbitan monooleate.
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PERSONAL ORAL HYGIENE COMPOSITION AND DEVICE

(WO2002026078) 04.04.2002 A46B 15/00 ALEXANDER, Carl, Ernest
This invention provides a dental hygiene system, incidentally attractive to children, based on a free-flow 'toothpaste' composition in the form of a plurality of beads each having substantially impervious walls; each portion or bead including about enough toothpaste for an average cleaning procedure. Bead consistency, flavour, colour, shape, or size, can be varied, for sale as mixtures or as single kinds. A toothbrush having a handle modified with one or more internal cavities (one holding oral hygiene tables; the other holding dental hygiene beads) is included in the system. Preferred bead manufacture involves formation in a mould and selective drying of the bead wall. The novel toothpaste makes a substantial contribution to reduction of e...
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CARCASS CLEANING DEVICES AND METHODS

(WO2002026045) 04.04.2002 A22B 5/00 FOOD PRO SYSTEMS LIMITED
One embodiment provides a carcass cleaning system comprises: a vacuum source; a cleaning head (1), having walls (2, 4, 6) defining a vacuum chamber (8) in communication via a vacuum line with the vacuum source, the vacuum chamber (8) having an open vacuum mouth (10); and a pressurised cleaning fluid supply (30), which supplies said cleaning fluid via a fluid line (28) to one or more cleaning fluid outlets (26) within the vacuum chamber (8), the cleaning outlets (26) being directed to spray cleaning fluid towards the vacuum mouth (10); whereby the vacuum mouth (10) may in use be positioned adjacent or against a carcass (13) to allow sprayed cleaning fluid to contact the carcass and be removed under vacuum via the vacuum line. In a second emb...
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PALATOMETER AND NASOMETER APPARATUS

(WO2002025635) 28.03.2002 A61B 5/00 LOGOMETRIX CORPORATION
A palatometer (10) and nasometer (20) apparatus for the diagnosis and treatment of speech impairment, new language sound learning, and other uses. The palatometer (10) includes a palatal body (40) containing electrodes (14) which fits in a user's mouth. Contact between the user's tongue or lips and the electrodes is indicated on display equipment (16). The palatometer (10) and display equipment (16) operate to indicate the position and movement of the tongue and lips. The nasometer (20) includes interchangeable sound operator plates (21) to fit users with different facial curvatures. Microphones (22, 23) are attached to the top and bottom of the sound separator plate (21) to measure sound emitted from the nose and mouth for determining the ...
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A CAPSULE FOR CLOSING CONTAINERS

(WO2002024541) 28.03.2002 B65D 47/24 BORMIOLI ROCCO &FIGLIO S.P.A.
The capsule for closing containers comprises a first cap (2) provided with an outlet mouth for the liquid in the container, screwed on to mouth (3) of a container. An annular element (6), coupled to the first cap (2) has a lower part which is destined to detach on first opening of the capsule. The first cap (2) can assume a closed lower position, in which the outlet mouth is closed by an upwardly-projecting part of an obturator (8), and an upper open position, in which the outlet mouth is distant from the projecting part. A second cap (11), external to the first cap (2), is internally provided with a projection (12) coupled with the first cap (2) and optionally located on an easy-break security strip. The capsule guarantees an airtight seal...
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SQUEEZE APPARATUS FOR TOOTHPASTE

(WO2002024538) 28.03.2002 B65D 35/38 CHEN, Wenqu
The present invention disclosed a squeeze apparatus for toothpaste, which comprises a toothpaste tube and an end cap that are engaged each other by thread. The top of end cap is in narrow and flat form and extends to form an inserting piece. An outlet for toothpaste is disposed on the inserting piece. The outlet is communicated to the inside of the toothpaste tube. The present invention can overcome the defects that the squeezed toothpaste is distributed only on the surface of the brush, and that the toothpaste can easily slip out of mouth before foaming during cleaning teeth, and much toothpaste is wasted when using the ordinary squeeze apparatus for toothpaste. The present invention has adantages of simple structure, convenient use, and l...
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DISPOSABLE DENTAL CARTRIDGE FLOSSER

(WO2002024105) 28.03.2002 A61C 15/04 PABLO, Gerardo
Our invention relates to a particular application is for the device to be able to effectively floss and clean one's teeth free of food debris, plaque, tartar, and other such material imbedded in-between one's teeth, in particular after having a meal. The device's main focus is to replace the awkward us of tying and twining the dental floss thread into one's fingers and hands (use of the right hand and left hand) to floss one's teeth by having a factory made and manufactured individual cartridge type disposable flosser one can load the cartridge flosser and after each use one can remove, throw away or rinse it if desired. One can also replace it with a new, unused cartridge. The invention is designed not only to eliminate the use of one's ha...
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CONCURRENT TOOTH REPOSITIONING AND SUBSTANCE DELIVERY

(WO2002024100) 28.03.2002 A61C 7/08 ALIGN TECHNOLOGY, INC.
The present invention provides devices, systems and methods for orthodontic treatment using elastic repositioning appliances while concurrently providing dental and periodontal therapies. The appliance (10) comprises a polymeric shell (12) having cavities (14) shaped to receive and resiliently reposition teeth from one tooth arrangement to a successive tooth arrangement. The polymeric shell may include a layer of agent (15), an agent gel or putty (22), a controlled release sheet (25) or reservoirs (60) for holding and dispensing therapeutic agents during orthodontic treatment.
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METHOD AND COMPOSITION FOR DENTAL BLEACHING

(WO2002022097) 21.03.2002 A61C 19/06 HIGH TECH LASER
This invention relates to a method for bleaching teeth that have been discoloured by a staining agent. The method comprises the steps of coating an area of at least one tooth to be bleached with a dental bleaching composition and irradiating the coated area with laser energy for a predetermined period of time to activate an oxidising agent contained in the bleaching composition, the activated oxidising agent being capable of reacting with the staining agent to at least partly discolour the staining agent. In the method of this invention use is made of a laser emitting laser energy of a wave length capable of inducing a photochemical generation of radicals of the oxidising agent, which radicals in turn are capable of reacting with the staini...
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ORAL COMPOSITIONS FOR MOISTRIZING THE ORAL CAVITY

(WO2002022096) 21.03.2002 A23G 4/00 THE PROCTER &GAMBLE COMPANY
The invention relates to a oral compositions comprising from 0.1% to 15% of a polyol carboxylic acid ester having a polyol moiety and at least 4 carboxylic acid moieties, wherein the polyol moiety is selected from sugars and sugar alcohols containing from about 4 to about 8 hydroxyl groups, and wherein each carboxylic acid moiety has from about 8 to about 22 carbon atoms. The compositions further comprise from about 0.1% to about 15% of an orally-acceptable surfactant, and an orally-acceptable carrier. the compositions, which are preferably in the form of a toothpaste, liquid dentifrice, chewing-gum, mouthwash or oral gel, can provide improved mouth feel and also benefits in oral moisturisation, including relief of dry mouth or avoiding its...
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METHOD FOR THE PREPARATION OF DENTAL PROSTHETIC ARTEFACTS BY MEANS OF POWDER SINTERING

(WO2002022041) 21.03.2002 A61C 13/00 NOBIL METAL S.P.A.
The present invention relates to a method for obtaining dental prosthetic artefacts, corrections, additions, welds and the like, which method uses the sintering of powders of metal alloys in common dentistry furnaces and comprises the following phases: adapting a plate of metallic powder with organic compounds added, modelling said adapted plate, coating the prepared item with refractory coating material mixed with an organic liquid and sintering the prepared item. The present invention further presents the advantage of enabling to work directly on the master model, avoiding the duplication step with the consequent time saving and with greater precision.
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GRANULAR PREPARATIONS FOR ORAL ADMINISTRATION

(WO2002019993) 14.03.2002 A61K 9/50 MITSUBISHI PHARMA CORPORATION
Granular preparations for oral administration wherein an anion exchange resin is contained as the active ingredient and cores of 3 to 4 mm in diameter are coated with a water-soluble polymeric cellulose as an inner coating layer and an aqueous dispersion of ethyl cellulose as an outer coating layer. Owing to this constitution, these preparations show no sliminess characteristic to cellulose, are free from adhesion of grains in the mouth and have a favorable texture at administration without any unacceptable feel as in large tablets.
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A TOOTHBRUSH WITH TOOTHPASTE LOADED INSIDE IT, FOR REUSE

(WO2002019867) 14.03.2002 A46B 11/00 LEVI, Tomer
A toothbrush includes a short arm (5) having bristles (1) on one end and the opposite end connected to a receptacle (8) containing toothpaste. The bottom end of the arm (5) includes a connector (7) leading from a departure hole (10) at the upper base (9) of the receptacle (8) to the brush (1). Toothpaste leaves the receptacle (8) through the departure hole (10) into a channel along the arm (5) and up to a spring-like push-button (6) located on the arm (5). Squeezing the push-button (6) allows paste to flow through the channel (3) and through two short flexible pipes (2) and up into the bristles (1). The brush (1) may also include a transparent cover (13) thereon. The receptable (8) is shaped as an easy, comfortable handle for use. When the ...
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APPARATUS FOR TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND ASSOCIATED METHOD

(WO2002018001) 07.03.2002 A61M 15/00 PNEUMOFLEX SYSTEMS, L.L.C.
An apparatus and method for treatment of a patient having a pulmonary disease involving chronic obstruction of the airways includes a container having therein a chamber containing a composition of L-tartrate in a pharmaceutically acceptable carrier; an opening connected to the chamber so as to provide an outlet thereof, the opening sized for producing droplets of a predetermined size range responsive to the composition being motivated from the chamber through the opening; and a source of motivating force connected with the chamber so as to motivate the compositions through the opening to thereby cause nebulization of the composition. A treatment kit comprises the container described and a mouthpiece connectable to the container so as to be ...
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HANDPIECE FOR A MEDICAL LASER TREATMENT DEVICE, AND A CORRESPONDING LASER TREATMENT DEVICE

(WO2002017811) 07.03.2002 A61B 18/00 W &H DENTALWERK BRMOOS GMBH
The invention relates to a handpiece for a medical laser treatment device, particularly a dental handpiece, comprising a laser light outlet for a laser beam that is guided at least partially through the handpiece, whereby the laser light outlet is located on a treatment side of the handpiece. The inventive handpiece also comprises a closing disc (40) made of a material through which the laser beam can pass, whereby the closing disc essentially closes the laser light outlet. The handpiece also comprises a shielding and/or cleaning device (68, 70) for the closing disc. The invention also relates to a corresponding medical laser treatment device.
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AQUEOUS TOOTHPASTE COMPRISING A CARRIER CO-GROUND WITH AN ACTIVE

(WO2002015856) 28.02.2002 A61K 8/21 UNILEVER N.V.
Oral composition comprising a co-ground of at least two ingredients which are co-ground without the use of solvents and wherein the co-ground comprises each of at least two ingredients at a level of at least 5 % by weight of the total weight of the co-ground, characterised in that the composition is an aqueous composition.
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DENTAL RESTORATIVE COMPOSITIONS AND METHOD OF USE THEREOF

(WO2002015848) 28.02.2002 A61K 6/083 JENERIC/PENTRON INCORPORATED
A curable dental restorative composition having a curable, ethylenically unsaturated component, preferably a hydrophilic, methacrylate-containing monomer or oligomer component, a calcium silicate cement component, and a non-water curing component. Water and/or fillers may optionally be present . The use of curable monomers or oligomers as part of the hardening agent for the cement component results in improved setting time and physical properties in the cured product. Water and/or fillers may optionally be present.
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DENTAL CURABLE COMPOSITION

(WO2002015847) 28.02.2002 A61K 6/083 TOKUYAMA CORPORATION
A dental polymerization-curable composition which has excellent workability in filling and reduced polymerization shrinkage and can become a dental composite repair material which has high flexural strength, is excellent in surface smoothness and luster and in wearing resistance, and is highly compatible in color tone with natural teeth after repair.
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DENTAL COMPOSITION FOR HYPERSENSITIVE TEETH

(WO2002015809) 28.02.2002 A61K 6/00 BLOCK DRUG COMPANY, INC.
A composition for the treatment of sensitive teeth comprising a suitable carrier and a desensitizing amount of: a) at least one tubule blocking agent, preferably a combination of two such agents; and b) a nerve desensitizing agent selected from the group consisting of at least one potassium salt, at least one strontium salt, and mixtures thereof, wherein the tubule blocking agent deposits or swells upon the dentinal surface and/or precipitates within the dentinal tubules, retaining a higher concentration of the nerve desensitizing agent at the exposed dentinal surface and within the dentinal tubules. The compositions may further contain a source of physiologically acceptable fluoride ion, such as stannous fluoride. Also disclosed are method...
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DISPOSABLE, FINGER WORN TOOTHBRUSH

(WO2002015736) 28.02.2002 A45D 44/18 DUNN, Gary, D.
A flexible, disposable toothbrush and hygiene kit incorporating the same. The toothbrush (10) comprises an elastomeric sheath (12) which can be slipped over the user's finger. A patch of bristles (18) is located on the closed end of the sheath(12). Constituent material of the sheath (12) is thin, flexible, and capable of receiving and maintaining indicia printed (20) in ink. The constituent material of the sheath (12) or the bristles (18) or both is impregnated with a flavoring agent. The toothbrush (10) may be incorporated into a kit providing dentifrice stored in a readily frangible capsule (26) and dental floss (204).
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INTEGRIN BINDING MOTIF CONTAINING PEPTIDES AND METHODS OF TREATING SKELETAL DISEASES

(WO2002014360) 21.02.2002 A61K 38/00 ACOLOGIX, INC
Peptide sequences comprising 10 to 50 amino acids are disclosed. The sequences are characterized by containing at least one of an integrin binding motif such as an RGD sequence, a glycosaminoglycan binding motif, and a calcium binding motif, and the remainder of amino acids contiguous with the RGD sequence in matrix extracellular phosphoglycoprotein. The sequences may be formulated for injection or dispersed in toothpaste or a mouthwash or gum patch and administered to enhance bone/tooth growth and/or reduce excessive urinary phosphate loss from the body.
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DENTAL PRODUCTS COMPRISING BONE GROWTH ENHANCING PEPTIDE

(WO2002013775) 21.02.2002 A61K 8/64 BIG BEAR BIO INC.
Dental products such as toothpastes, mouthwash and dental floss are disclosed which products are enhanced by having dissolved, dispersed or coated thereon a compound which promoted bone growth. Preferred compounds are peptide sequences comprising 10 to 50 amino acids are disclosed. The sequences are characterized by containing an integrin binding motif such as RGD sequence and the remainder of amino acids contiguous with the RGD sequence in matrix extracellular phosphoglycoprotein. The sequences may be formulated for dispersed in toothpaste or a mouthwash and administered to enhance bone/tooth growth. When the dental products are used repeatedly over time they enhance good dental health.
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CALCIUM CARBONATE COMPOSITIONS FOR USE IN THE MANUFACTURE OF TOOTHPASTE

(WO2002013774) 21.02.2002 A61K 8/19 QUMICA INDUSTRIAL BARRA DO PIRA LTDA.
An aqueous suspension of particulate calcium carbonate for use in the manufacture of toothpaste compositions includes in addition to the calcium carbonate one or more dispersing agents and one or more preservative agents and wherein the aqueous medium of the suspension has been treated so that the biological contamination of the suspension is not greater than the maximum allowable levels indicated by the US Food and Drugs Administration (FDA). The calcium carbonate may comprise a precipitated and/or ground calcium carbonate. The suspension may have a solids content of from 50 % to 99.5 % by weight. The suspension may be flowable and pumpable.
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DENTAL COMPOSITIONS COMPRISING BISACRYLAMIDES AND USE THEREOF

(WO2002013768) 21.02.2002 A61K 6/083 DENTSPLY INTERNATIONAL, INC.
The invention concerns a dental composition comprising bisacrylamides that are polymerizable by free-radical polymerization and by Michael-addition polymerization with amines. The application of polymerization and addition polymerization with amines opens the possibility to completely reached materials that have no oxygen inhibited layers. The claimed bisacrylamides have an improved hydrolytic stability.
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DENTAL CARE DEVICE

(WO2002013721) 21.02.2002 A61C 1/00 NORDMO, Jon
A pneumatic dental care device for private use which by means of a combination of air, liquid and powder at high pressure cleans the user's teeth and removes plaque and discoloration. The device consists of a base unit (100) and a hand unit (300) which are connected via a flexible, sheathed tube and wire bundle (200). The base unit contains a microcompressor (120), a liquid container (130) and a powder container (140). Liquid and/or powder are discharged at high pressure through an exchangeable nozzle unit (400) on the hand unit. The nozzle unit consists of one or more flexible (bendable) jet stems (401). The microprocessor, the powder container and the liquid container can be replaced by an exchangeable compressed air tank and/or pressuris...
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A SORTING DEVICE FOR CONTAINERS

(WO2002012096) 14.02.2002 B65G 29/00 TOMRA SYSTEMS ASA
A device for controlling the conveying direction of liquid containers in the form of empty beverage packaging, for example, cans or bottles of any cross-section, where the conveying direction is either through a portion of the device, or sideways away from the conveying path where the containers are supported in a horizontal position, comprising a drum that is rotatably arranged above the conveying path and with its axis of rotation in the direction of the conveying path, wherein the drum has at least one container-adapted chamber, through-going in the direction of the axis of rotation, and with its mouth at the periphery of the drum, at least one container guide plate extending sideways and upwards from the conveying path along a portion o...
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SHAPED SUTURE CLIP, APPLIANCE AND METHOD THEREFOR

(WO2002011622) 14.02.2002 A61B 17/04 SCION INTERNATIONAL, INC.
The suture clip (10) includes a pair of plates (12, 14) joined together at one end to form a vertex (18) having an acute angle (16). Each plate, at its remote terminal end (21, 23), defines an inwardly facing hook (20, 22). The hook end members establish a clip mouth (25) slightly larger than the diameter of the suture thread such that when the thread is passed through the clip mouth, the thread cannot easily escape entrapment from the central region of the clip. The suture clip may be C-shape, V-shape, broken leg V-shape, heart shape or pentagonal shape. In another embodiment, the clip is a closed loop (510) or elliptical in shape. To enhance operability, the hooks (20, 22) on the C, U or V shape sutures are disposed on tabs (30, 32) which...
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DENTAL COMPOSITIONS

(WO2002007691) 31.01.2002 A61K 8/90 THE BOOTS COMPANY PLC
Compositions for inhibiting the adherence and formation of plaque and/or stains on the teeth, said compositions contain two poloxamers selected from a first group of poloxamers having a melting point in the range 48 to 58 degrees C and having a HLB value in the range 22 to 29 and a second group of poloxamers having a melting point in the range 27 to 35 degrees C and having a HLB value in the range 8 to 17; said poloxamers being selected from the same or different groups.
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DENTAL COMPOSITIONS

(WO2002007690) 31.01.2002 A61K 6/00 THE BOOTS COMPANY PLC
Dental compositions to inhibit the adherence and plaque and/or stains on teeth comprise one or more water-soluble block copolymers of polyoxyethylene/polyoxypropylene which have a structure with the polyoxypropylene block being sandwiched between two polyoxyethylene blocks together with an acidic poly-amino acid or an alkali metal salt thereof.
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A TOOTHPICK/DENTAL CLEANER WITH A TRAPEZOIDAL-SHAPED TRIANGULAR PROFILE, WITH A POINTED TIP AT ONE END AND A HOOK

(WO2002007642) 31.01.2002 A61C 15/02 SKINDBJERG HOLDING A/S
This invention is an effective toothpick (dental cleaner) which, owing to its unique shape, triangular profile/trapezoidal shape and hook, can clean the teeth and massage the gums, as well as effectively prevent the formation of dental tartar due to the slight roughness on the dental cleaner, and is therefore effective in the prevention of plaque and periodontitis. The product is the only one of its kind which has been designed to clean the space between the teeth and massage the gums irrespective of the size of these gaps, and it is the only one which is rough on both sides and at both ends. It is also the only one of its kind with the unique trapezoidal form shaped according to the shape of the teeth at the gum line and is thus effective ...
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TREATMENT ELEMENT FOR AN APPLIANCE FOR CLEANING DENTAL INTERSTICES, A METHOD AND DEVICE FOR THE PRODUCTION THEREOF

(WO2002007562) 31.01.2002 A46B 9/02 ESRO AG
The invention relates to a treatment element (1), which can be mounted onto an appliance for cleaning dental interstices. Said element comprises a shank (2), provided with bristles that radiate outwards (3). The brush head has a substantially polygonal, in particular triangular form (5). Said head can have a series of zones of different diameters along the shaft (2) and in particular, tapers (6) towards its end.
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RADIATION-CURABLE COMPOSITIONS AND CURED ARTICLES

(WO2002006371) 24.01.2002 C08F 283/10 SUNCOLOR CORPORATION
A radiation-curable composition in a liquid or solid form comprises at least one solid, non-crystalline radiation-transmissible material, dispersed in at least one cationic-curable or free-radical curable composition or mixture thereof. The solid, non-crystalline radiation-transmissible materials comprise glasses and other suitable materials that transmit (i.e, are transparent to) at least about 40% of radiation having a wavelength from about 180 to about 600 nanometers. The cationic-curable compositions comprise at least one cycloaliphatic epoxide, at least one polyol, and at least one cation-generating photoinitiator. The free-radical curable compositions comprise at least one ethylenically unsaturated compound and at least one free-radic...
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PEPTIDE COMPOSITION FOR TREATMENT OF PERIODONTAL DISEASES AND PREVENTION OF SKIN AGING

(WO2002002133) 10.01.2002 A61K 8/64 PEPSYN LTD
Provided is use of a peptide, or a derivative of a peptide, in the manufacture of a medicament effective in alleviating or preventing periodontal disease, wherein the peptide comprises an amino acid sequence present in an $g(a)-S2 casein precursor, said sequence comprising 3 or more amino acids, and not comprising at its N-terminus the N-terminal amino acid of the full $g(a)-S2 casein precursor. The peptide may alternatively be any peptide having an $g(a)-S2 casein fragment activity. Further provided is use of a peptide, or a derivative of a peptide, in the manufacture of a medicament effective in alleviating or preventing an effect of aging in skin, wherein the peptide comprises an amino acid sequence present in an $g(a)-S2 casein precurso...
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ORAL CARE COMPOSITIONS COMPRISING CHLORITE

(WO2002002061) 10.01.2002 A23K 1/18 THE PROCTER &GAMBLE COMPANY
The present invention relates to topical oral compositions, including therapeutic rinses, especially mouth rinses, as well as toothpastes, gels, tooth powders, chewing gums, mouth sprays, lozenges (including breath mints), dental implements (such as dental floss and tape), and pet care products comprising at least a minimally effective amount of chlorite ion, wherein the pH of the final composition is greater than 7 and the composition is essentially free of chlorine dioxide or chlorous acid. This invention further relates to a method for treating or preventing diseases and conditions of the oral cavity such as gingivitis, plaque, periodontal disease, herpetic lesions, and infections that may develop following dental procedures such as osse...
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ORAL COMPOSITIONS

(WO2002002060) 10.01.2002 A61K 8/24 THE PROCTER &GAMBLE COMPANY
The invention relates to oral compositions providing improved cleaning of teeth. The compositions comprise a cleaning silica, having a particle size ranging from 8 to 14 $g(m), an oil absorption ranging from 60 to 120 cm?3/100 g, and a mercury intrusion (HGI) void volume of 1.0 to 4.0 cm?3/g; the silica, when formulated into a dentifrice, having a Pellicle Cleaning Ratio (PCR) of from 70 140 and a Radioactive Dentin Abrasion (RDA) value of from 60 to 130, wherein the ratio of the PCR to the RDA is at least 1.1. The compositions further comprise a phosphate ester of myo-inositol, such as phytic acid, or a salt thereof.
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TOOTHPASTE DISPENSER

(WO2001098163) 27.12.2001 B65D 35/28 INNOVATIVE INJECTORS, INC.
An apparatus (10) for dispensing a substance from a collapsible substance containing tube (70), the tube (70) having an outlet opening (76) through which the substance is dispensed, the apparatus (10) comprising a housing (12), a slider (50) positioned within the housing (12), the slider (50) having a passage (64) therethrough, first (60) and (62) second flexible members passable through the passage (64) in the slider (50), the first (60) and second (62) flexible members for exerting pressure on the tube (70), a rod (30) for supporting the slider (50) within the housing (12), the slider (50) being movable along a length of the housing (12) along the rod (30) upon the rotation of the rod (30) and a motor (26) couplable to the rod (30) for ca...
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MATRIX PROTEIN COMPOSITIONS FOR DENTIN REGENERATION

(WO2001097834) 27.12.2001 A61K 6/00 BIORA AB
The present invention relates to the surprising finding that enamel matrix, enamel matrix derivatives and/or enamel matrix proteins induce dentin regeneration. The invention thus relates to the use of a preparation of an active enamel substance for the preparation of a pharmaceutical composition for the formation or regeneration of dentin following dental procedures involving exposure of vital dental pulp tissue. In another aspect, the invention relates to a method of promoting the formation or regeneration of dentin following dental procedures involving exposure of vital dental pulp tissue, the method comprising applying an effective amount of an active enamel substance on exposed vital dental pulp tissue after dental procedures.
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PROCESS FOR MAKING TOOTHPASTE USING LOW LEVELS OF CARRAGEENAN

(WO2001097767) 27.12.2001 A61K 8/24 FMC CORPORATION
A process for increasing by at least about 100 % the viscosity of a carrageenan-containing dentifrice composition is disclosed. The process comprises allowing the composition to quiescently cool from a temperature at or above about 45 C. The process may be applied to making toothpastes having suitable viscosity using carrageenan levels as low as about 0.05 weight percent. The dentifrice compositions are comprised of one or more of the following carrageenans: iota, modified kappa, or mixtures thereof. Toothpastes prepared using this method are easier to process and require much less carrageenan relative to similar viscosity toothpastes prepared by previous methods.
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CLEANING AND DESINFECTION OF MICROBIALLY COLONIZED WATER SYSTEMS

(WO2001095948) 20.12.2001 A01N 47/44 HALLN, Jan-ke
A method for cleaning and disinfection of microbially colonized water systems comprising for example medical, dental or laboratory equipment, which via conduits (34) and at least one valve (36) is connected to the water system (14) and to a container (12) for a treatment medium, which can be set under pressure in said container, for flushing the conduits and the equipment. In a first valve position - emptying position - the water to the container is shut off and a connection to an outlet (30) from the container is opened at the same time, so that the container and the equipment and the conduits thereto are emptied. In a second valve position - filling position - all connections to the container are shut off and a treatment medium is introdu...
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ZEOLITE COMPOSITIONS AND THEIR USE

(WO2001094512) 13.12.2001 A61Q 11/00 INEOS SILICAS LIMITED
A method of using a zeolite composition comprises forming a mixture of (a) a crystalline aluminosilicate and (b) a salt of a second metal selected from the group consisting of Group III metals, metallic elements of Group IV, magnesium, titanium, chromium, iron, nickel, copper, zinc, zirconium and silver, said salt of a second metal being present in an amount which is sufficient to replace from about 2.0 to about 40 per cent of a first metal moiety, and using said mixture in an aqueous composition at a pH in the range 4 to 10. A further aspect of the invention is a powder comprising a mixture of (a) a crystalline aluminosilicate and (b) a salt of a second metal selected from the group consisting of Group III metals, metallic elements of Grou...
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PROTECTIVE SEAL FOR CANS

(WO2001094232) 13.12.2001 B65D 51/20 DEROSE, Mark, V.
A protective seal (10) for beverage cans (c) completely covers and seals the mouth contact area (14) of the can (9c), thereby protecting that area from contamination due to handling and storage. The seal (10) comprises a thin, durable, impervious sheet applied to the top (T) of the can (c) surrounding the opening area (M), extending down the upper side of the can adjacent the top opening area for a short distance. This comprises the mouth contact area (M) of the can, and the seal (10) completely seals and protects this area. The seal is sealed to the can surface by a narrow strip (18) of food grade adhesive about the perimeter (16) of the seal, with the adhesive passing around the front of the pop tab pull ring (R) of the can top. The seal ...
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TOOTHPASTE COMPOSITION HAVING REDUCED DENTIN ABRASIVITY

(WO2001093821) 13.12.2001 A61K 8/25 ACCESS BUSINESS GROUP LLC
A toothpaste composition comprising a kaolin and a non-abrasive silica. The kaolin is the sole abrasive present in the composition. The composition has an RDA less than about 10.
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MICRO-HYBRID COMPOSITE WITH ADDED GLASS FIBRES

(WO2001093809) 13.12.2001 A61K 6/083 MARQUANT, Philippe
The invention concerns the field of esthetics and dental restoration and consists in the preparation of a mixture of composite and glass fibre and the method for making said preparation. The inventive micro-hybrid composite contains longitudinal silanized glass fibres ? 0.23 mm; it compositions is as follows: 82 % of crystalline mineral fillers; 17.67 % of organic resins; 0.29 % of additives.
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A DISPOSABLE TOOTHBRUSH

(WO2001093721) 13.12.2001 A46B 11/00 SARGENT, Bruce, Alan
This invention relates to a toothbrush and toothpaste dispenser unit. The toothbrush includes a longitudinally extending brush head attached to a brush handle, the brush head defining a first surface and an opposed second surface. A plurality of bristles extending from the first surface on the brush head. The toothbrush also includes a supply cavity, which is defined by a cap, for containing a supply of toothpaste and which is arranged to abut with the second surface on the brush head, the cap being movable from a first inoperative position, laterally relative to the brush head, to a second operative position. At least one aperture extends through the brush head, from the first surface to the second surface, for bringing the supply cavity i...
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SULFUR COMPOUND AND USE THEREOF

(WO2001092252) 06.12.2001 C07D 339/00 MITSUI CHEMICALS, INCORPORATED
A sulfurized (meth)acrylic ester compound represented by the formula (1) (wherein R1? and R2? each represents hydrogen or alkyl and may be bonded to each other to form a ring; R3? represents hydrogen or methyl; X1? represents oxygen or sulfur; m is an integer of 0 to 3; and n is an integer of 1 to 4); a polymerizable composition containing the (meth)acrylic ester compound; a cured article obtained by polymerizing the polymerizable composition; and an optical part. The sulfurized (meth)acrylic ester compound is highly useful as a monomer for photocurable polymerizable compositions in applications such as optical materials and dental materials. The optical part, which is obtained by curing the polymerizable composition, is excellent i...
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USE OF EXOGENOUS LACTIC BACTERIA STRAIN AGAINST ACTINOMYCES NAESLUNDII RELATED DISEASES

(WO2001091711) 06.12.2001 A23C 9/123 SOCIETE DES PRODUITS NESTLE S.A.
The use of a lactic bacteria strain that is exogenous to the oral microflora, which has been selected for its ability to adhere the pellicle of the teeth and to produce a growth inhibition factor, for the preparation of a composition intended for reducing dental plaque and for treating or preventing root caries and other diseases related to Actinomyces naeslundii in mammals.
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DEODORIZING/ANTIFOULING COMPOSITION FOR DENTAL PRODUCT

(WO2001091701) 06.12.2001 A61K 6/027 NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
A dental resin material containing a composition which contains, as a main component, titanium dioxide whose surface has been partly coated with apatite. The titanium dioxide in this dental resin material is preferably anatase-, rutile-, or brookite-form titanium dioxide or a mixture of these. The apatite with which the titanium dioxide is to be partly coated is generated by immersing powdery titanium dioxide in a pseudo body fluid with stirring while keeping the mixture at a temperature almost the same as the human body temperature, i.e., at about 36C. It is important for this apatite to be deposited as platy crystals having a thickness of 2 mm or smaller so as to cover 0.001 to 10% of the surface of the titanium dioxide.
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COMPOSITION AND APPLICATOR FOR TOPICAL SUBSTANCE DELIVERY

(WO2001091682) 06.12.2001 A61K 9/00 SOLUBLE SYSTEMS, LLC
A polymerized hydroge composition and applicator for hydrating or dehydrating a surface, particularly a dermatological surface, to which it is applied and a method for forming the composition. The composition is comprised of a mixture of two polymerizable materials, a two-part redox catalyst system and a two-part polymerization medium. The percentage by weight of each element in the composition may be varied within stated percentage ranges. The rate at which hydration of dehydration occurs may be controllably altered by varying the percentages of certain of the composition elements. The applicator includes a thermoplastic center section and two reservoir sections each having a reservoir storage area for holding moisture and/or medicaments. ...
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NON-BLOCKING ELASTOMERIC BAGS

(WO2001089947) 29.11.2001 B65D 33/28 PACTIV CORPORATION
A drawtape bag (10) comprising a pair of pliable thermoplastic body panels (12,14), a pliable drawtape (24) and an elastomeric strip (30). The pair of pliable thermoplastic body panels are joined to each other along a pair of opposing sides (16a,16b) and a bottom (18) bridging the opposing sides. At least one of the body panels forms a hem (22) extending along a mouth end disposed opposite the bottom. The hem includes one or more drawtape holes (26a,26b). The pliable drawtape is housed within the hem and includes a gathered section (32). The drawtape is partially exposed by the drawtape holes which allow the drawtape to be pulled therethrough to close the bag and to be used as a handle. The elastomeric strip is connected to the gathered sec...
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INHALATION THERAPY DECONGESTANT WITH FORAMINOUS CARRIER

(WO2001089475) 29.11.2001 A61K 9/00 LEC TEC CORPORATION
A vaporizable decongestant is supported and stabilized on a flexible foraminous carrier composed typically of open-cell plastic foam, cloth or other fibrous material such as nonwoven fabric. The term 'foraminous' herein is intended to refer to a substance or medium containing minute openings or perforated by many minute apertures. The decongestant is placed on the surfaces within the interstices and minute apertures or on fibers from which the foraminous carrier is formed. Vaporization of the inhalable decongestant is facilitated by providing the potential for greatly increasing its exposed surface area. Distributing the decongestant composition over the large, expanded surface within the foraminous carrier is beneficial in enhancing both t...
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LICE COMB CLEANING DEVICE

(WO2001089342) 29.11.2001 A45D 24/40 NATIONAL PEDICULOSIS ASSOCIATION, INC.
A lice comb cleaning tool (10) includes a handle (12), a pair of spaced-apart arms (14, 16) depending from the handle (12) and an elongate member (18) supported at distal ends of the pair of arms. The elongate member has a diameter selected for an interference fit between tines of a lice comb (30). It is preferred that the elongate member be unwaxed dental floss.
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MICELLAR PHARMACEUTICAL COMPOSITIONS FOR BUCCAL AND PULMONARY APPLICATION

(WO2001087268) 22.11.2001 A61K 9/00 GENEREX PHARMACEUTICALS INC.
Pharmaceutical compositions comprising a macromolecular pharmaceutical agent in mixed micellar form are disclosed. The mixed micelles are formed from an alkali metal alkyl sulfate, and at least three different micelle-forming compounds as described in the specification. Micelle size ranges between about 1 and 10 nanometers. Methods for making and using the compositions are also disclosed. A preferred method for administering the present composition is through the buccal region of the mouth.
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FLUORIDE-RELEASING AMALGAM DENTAL RESTORATIVE MATERIAL

(WO2001087241) 22.11.2001 A61K 6/05 MCG RESEARCH INSTITUTE
A fluoride-releasing dental amalgam composition for a tooth restoration comprising a dental amalgam alloy material and a fluoride-containing, the glass particulate powder component of a fluoride-leachable acid-etchable glass ionomer cement. The invention further provides a method for using the composition to prevent or reduce secondary caries in an existing tooth restoration, which is classified as a dental amalgam in nature.
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APPARATUS AND METHOD FOR ACCELERATING DENTAL TREATMENTS

(WO2001085052) 15.11.2001 A61C 9/00 ULTRADENT PRODUCTS, INC.
Apparatus, kits and methods for providing accelerated treatment of a patient's teeth. The apparatus, kits and methods involve the use of a dental impression tray (10) that includes a dental impression material (16) such as an alginate. The impression tray (10) advantageously includes heating wires (34) coupled by connectors (36) to a power supply (32). The heating wires (34) are used for heating and maintaining the formed impression tray (10) at a temperature greater than about 105 F. The heated dental trays may be used to accelerate the activity of dental bleaching agents (e.g., peroxides), desensitizing agents (e.g., potassium nitrate), remineralizing agents (e.g., fluoride salts), and the like. A dental office procedure for treating te...
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METHODS FOR ACCELERATED DESENSITIZATION OF TEETH

(WO2001085049) 15.11.2001 A61C 9/00 ULTRADENT PRODUCTS, INC.
Apparatus, kits and methods for providing accelerated treatment of a patient's teeth. The apparatus, kits and methods involve the use of a dental impression tray (10) that includes a dental impression material (16) such as an alginate. The impression tray (10) advantageously includes heating wires (34) coupled by connectors (36) to a power supply (32). The heating wires (34) are used for heating and maintaining the formed impression tray (10) at a temperature greater than about 105 F. The heated dental trays may be used to accelerate the activity of dental bleaching agents (e.g., peroxides), desensitizing agents (e.g., potassium nitrate), remineralizing agents (e.g., fluoride salts), and the like. A dental office procedure for treating te...
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THE USE OF BACTERIAL PHAGE ASSOCIATED LYSING ENZYMES FOR TREATING VARIOUS ILLNESSES

(WO2001082945) 08.11.2001 A61K 38/46 NEW HORIZONS DIAGNOSTIC CORPORATION
A composition and method for treating bacterial infections is disclosed which comprises the treatment of an individual with an effective amount of at least one lytic enzyme produced by a bacteria infected with a bacteriophage specific for said bacteria wherein at least one lytic enzyme is selected from the group consisting of shuffled lytic enzymes, chimeric lytic enzymes, holin enzymes, and combinations thereof. A carrier may be used for delivering the lytic enzyme. This method, and composition can be used for the treatment of upper respiratory infections, skin infections, wounds, and burns, vaginal infections, eye infections, intestinal disorders and dental problems.
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TOOTH CLEANING AGENT

(WO2001082883) 08.11.2001 A61K 8/22 WIGET WIGET &PARTNER GMBH
A tooth cleaning agent for preventive dental hygiene, such as toothpaste or a prophylaxis paste, containing ground borosilikate glass as an abrasive agent in addition to the usual additives, thickening agents, emulsifiers, fluorides and the like. The particle size of the ground glass is < 200 $g(m)m, preferably < 100 $g(m)m and the average particle size is < 50 $g(m)m, preferably < 30 $g(m)m, more preferably < 20 $g(m)m. The proportion of borosilikate in the tooth cleaning agent recipe is $m(F) 65 wt. %.
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BACK-UP SHEAR PLATE AND SHIM FOR WINDOWS

(WO2001081059) 01.11.2001 E06B 1/60 STORE FRONT SUPPLIES, INC.
The plastic back-up shear plate (60) is laterally disposed with generally a spring fit into the outwardly facing mouth of a metal window frame (10). The outwardly facing frame mouth is formed and defined by the window frame elongated hollow body (36) and particularly by outer wall elements which face each other in an opposing manner. The plastic back-up shear plate (60) has laterally disposed opposite outer edge portions which are interlockable on corresponding outer wall elements of hollow body (36) metal window frame which wall elements (18) define the mouth of the window frame. In a perpendicular direction, the back-up shear plate has a opposing edge portions with interlock on window frame mouths having a slightly different dimension. Th...
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COMPOSITION EXHIBITING ENHANCED FORMULATION STABILITY AND DELIVERY OF TROPICAL ACTIVE INGREDIENTS

(WO2001080823) 01.11.2001 A61K 8/11 SOL-GEL TECHNOLOGIES LTD.
A therapeutic or cosmetic composition for topical application, capable of stabilizing an active ingredient and delivering said ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 microns. The core of each microcapsule includes at least one active ingredient, and is encapsulated within a microcapsular shell, The shell is comprised of at least one inorganic polymer obtained by a sol-gel process, and the shell protects the active ingredient before topical application and releases the ingredient after topical application. This composition is useful to encapsulate active ingredients that are unstable in formulation, or are irritating to the skin. The pre...
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A TEXTURIZED DENTAL FLOSS

(WO2001080770) 01.11.2001 A61C 15/04 JOHNSON &JOHNSON INDSTRIA E COMRCIO LTDA.
A texturized dental floss formed of a bundle of texturized filaments (1) and comprising, in each floss extension unit: cleaning portions (10) having a determined longitudinal extension and circumferential contour, which are previously defined in the bundle of texturized filaments (1); and fastening portions (20), each being provided between two consecutive adjacent cleaning portions (10), having a determined longitudinal extension in which the filaments are cohered and contained in a circumferential contour, which is substantially reduced in relation to that of the cleaning portion (10), said fastening portions (20) being provided in order to maintain substantially unaltered the elasticity and flexibility characteristics of the bundle of fi...
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MECHANISM FOR ANIMATED CHARACTER

(WO2001078857) 25.10.2001 A63H 3/36 MERRIMENT INC.
Character (2) capable of forming facial expressions is provided with hollow head (4) with a face defining mouth (6) thereon. Mouth (6) has a length and includes first end portion (6a) and second end portion (6b). Character (2) further includes mechanism (7) for causing various facial expressions. Mechanism (7) includes mouth assembly (10) and drive assembly (12) fixedly mounted upon main frame plate (8). Mouth assembly (10) includes upper lip chain (14) which is formed from a plurality of links (16) with first end (14a) and second end (14b). Drive assembly (12) is adapted to move at least one of the first and second ends of upper lip chain (14) and at least one of the corresponding end portions of the mouth to cause various facial expressio...
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FOAMABLE DENTAL FLUORIDE COMPOSITION

(WO2001076533) 18.10.2001 A61K 6/00 COLGATE-PALMOLIVE COMPANY
A dental fluoride foam composition comprising a foamable fluoride containing composition that is packaged in a foam generating container, the composition being comprised mainly of, an aqueous solution of a water soluble fluoride ion releasable salt, a taurate surfactant whereby the composition when dispensed from the container into the trough of a dental tray forms a low density, rapidly collapsible foam which substantially liquefies in about 1 minute after being dispensed from the foam generating container and placed in contact with a patients teeth.
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A DENTAL FLOSS

(WO2001076503) 18.10.2001 A61C 15/04 JOHNSON &JOHNSON INDSTRIA E COMRCIO LTDA.
A dental floss formed of a bundle of texturized filaments (1) and comprising a retaining means (10) applied around the bundle of filaments (1), so as to maintain said filaments (1) cohered within a certain previously determined circumferential contour, but with a substantial part of their circumferential and longitudinal extensions being free to move radially and act as a removing element in the inter-dental space.
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TOOTHBRUSH FOR SINGLE USE

(WO2001076412) 18.10.2001 A46B 7/02 PORUBA, Milan
The toothbrush for single use is created so that the holder (2) and head (3) of the toothbrush (1) are with the same circular cross-section and that the holder (2) is equipped at the free end with coaxial recess (5) where the toothpick (6) is inserted. The head (3) of the toothbrush (1) is rounded at the end and equipped with spirally arranged hair (4) in the same length. The head (3) of the toothbrush (1) is equipped with spirally arranged hair (4), which is shorter towards the rounded end. The head (3) of the toothbrush (1) is equipped with spirally arranged hair (4), which is longer towards the rounded end. The head (3) of the toothbrush (1) is equipped with hair (4) which is arranged in three parallel lines, equally distributed around t...
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NEW FORMULATIONS FOR THE REMOVAL OF DENTAL PLAQUE, TARTAR AND DENTAL STAINS

(WO2001074324) 11.10.2001 A61K 8/44 FARINA, Paolo
Use of at least a substance selected from the group comprising: glutathione, pharmaceutically acceptable esters and salts of glutathione, WR-2721, sodium mercaptoethansulfonate (MESNA), diethyldithiocarbamate, sodium thiosulfate, N-acetylcysteine, cytochrome P450 and cysteamine as the active substance in the preparation of pharmaceutical compositions suitable for the removal of plaque, dental calculus (tartar) and dental stains from the tooth surface, also having an anti-halitosis function, and compositions thereof.
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ELASTIC TOP DRAWSTRING BAG AND METHOD OF MANUFACTURING THE SAME

(WO2001072595) 04.10.2001 B31B 19/90 PACTIV CORPORATION
A drawtape bag (10) comprises a pair of pliable thermoplastic body panels (16) joined to each other along a pair of opposing sides and a bottom (18) bridging the opposing sides. The bag (10) may be opened along the mouth end (20) formed opposite the bottom (18). At least one of the body panels (16) forms a hem (22) along the mouth end (20) of the bag (10), and the hem (22) houses a pliable thermoplastic drawtape (24). One or more drawtape holes (26) located within the hem (22) expose the drawtape (24) allowing it to be pulled through the holes (26) to close the bag (10) and to be used as a handle. The elastic top feature is provided by an elastomeric strip (30) connected to a looped section of the drawtape (24) housed within the hem (22). S...
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OXIDATIVE FLUORINATOR COMPOUNDS AS ANTIMICROBIALS

(WO2001072275) 04.10.2001 A01N 59/10 MARANTECH HOLDING, LLC
The invention relates to a method and composition for destroying or inhibiting proliferation of microbes using oxidative fluorinator compounds. Fluoride salts that do not dissociate completely in aqueous solutions, such a tri- or tetravalent transition metal fluorides, inert gas fluorides, or tri- or tetravalent rare earth fluorides, are effective antimicrobial agents event at levels up to about 20 ppm, when used alone or in conjunction with a strong oxidizer.
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DENTAL CARE AGENTS PROVIDED IN THE FORM OF SINGLE-PORTION CAPSULES

(WO2001072274) 04.10.2001 A61K 7/16 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to dental care agents provided in the form of single-portion capsules which consist of a water-soluble material and are filled with a flowable preparation for cleaning and/or caring for the oral cavity and/or the teeth. The capsule material is comprised entirely or predominantly of cellulose esters, polyvinyl alcohol, polyethylene oxide or mixtures thereof. The flowable preparation contains at least 50 wt. % of a humectant from the group of glycols, glycol ethers or polyols with 2-6 C atoms, of polyethylene glycols or a mixture thereof, and contains at least one flavoring substance and no more than 10 wt. % water. The capsule material is preferably comprised entirely or predominantly of methylhydroxypropyl cellulose.
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DENTAL CONTACT MARKER

(WO2001072236) 04.10.2001 A61C 15/00 TERMINEL VALDEZ, Jorge
The marker is used to find the point of interproximal contact in dental restaurations and prothesis. It consists of a strip or thread, wax and pigment for wax. When passing it between the interproximal spaces, the pigment used remains on the dental piece, on the point where contact is made.
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A CORKSCREW

(WO2001070620) 27.09.2001 B67B 7/04 KANE, Stephen
A corkscrew assembly (50) has a tubular body (52) mounted on an upright slide bar (75) by means of a collar (72) which is connected to the body (52) by an arm (73). The slide bar (75) is carried by pillars (76) on a base plate (77) which in use is attached to a wall or the like above a horizontal work surface. The collar (72) can be moved up or down on the slide bar (75) for height adjustment of the body (52) to engage a mouth (85) at a lower end of the body (52) with the neck of a bottle placed on the work surface below the body (52). Locking means is provided on the collar (72) to releasably lock the collar (72) on the slide bar (75) when engaged with a bottle to securely hold the bottle for cork extraction. An actuating lever arm (68) on...
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A COMPOSITION CONTAINING MONOTERPENES FOR TOPICAL ORAL ADMINISTRATION

(WO2001070184) 27.09.2001 A61K 8/20 GINSOL LTD
The invention provides a composition for topical, oral administration for prevention and treatment of oral disease, comprising an active agent containing at least 70 % by weight monoterpenes with three unsaturations as active agent therein, in combination with a suitable carrier.
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TOOTHPASTE COMPOSITIONS CONTAINING CETYLPYRIDINIUM CHLORIDE

(WO2001070183) 27.09.2001 A61K 8/40 CHURCH &DWIGHT CO., INC.
A toothpaste composition containing an effective amount of cetylpyridinium chloride and a mixture of toothpaste forming ingredients including at least one amphoteric surfactant and optionally at least one sweetener.
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TOOTH WHITENING COMPOSITION

(WO2001070178) 27.09.2001 A61C 5/06 DENTSPLY INTERNATIONAL INC.
A dental tooth whitening material sets to a rubber-like or elastomeric yet fluid consistency. The material includes hydrogen peroxide. A method of whitening teeth employs such a material by placing it into a dental tray or by placing the material directly onto a tooth. Once the material has set to its solid or semi-solid yet fluid consistency, the dental tray, if employed, can be left in place or removed.
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STAIN REMOVING CHEWING GUM AND CONFECTIONERY COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME

(WO2001067884) 20.09.2001 A23G 3/00 WARNER-LAMBERT COMPANY
A composition in the form of a chewing gum composition or a confectionery composition containing stain removing agent selected from anionic and non-ionic surfactants and methods of preparing and using the same to remove stains from dental material including teeth.
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STABILIZED MICROFIBRILLAR CELLULOSE

(WO2001066600) 13.09.2001 C08B 11/145 HERCULES INCORPORATED
A derivatized microfibrillar cellulose, derivatized to contain a substituent that provides cationic charge. A method for producing a derivatized microfibrillar cellulose to include a substituent that provides cationic charge, which may include derivatizing a microfibrillar cellulose to obtain a derivatized microfibrillar cellulose, microfibrillizing a derivatized non-microfibrillar cellulose to produce a derivatized microfibrillar cellulose, or microfibrillizing and derivatizing a non-microfibrillar cellulose substantially simultaneously. A method of modifying the rheological properties of a composition of matter using derivatized microfibrillar cellulose. Methods of improving coatings, paper manufacture, and the stability of emulsions, dis...
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ENZYME CAPABLE OF HYDROLYZING PLAQUE, MICROORGANISM PRODUCING THESAME, AND A COMPOSITION COMPRISING THE SAME

(WO2001066570) 13.09.2001 A61K 8/66 KIM, Doman
The present invention relates to a dental plaque hydrolyzing or inhibiting enzyme, a preparation method thereof, a composition containing the same and microorganism producing the same.
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MICELLAR PHARMACEUTICAL COMPOSITIONS FOR BUCCAL AND PULMONARY APPLICATION

(WO2001066085) 13.09.2001 A61K 9/00 GENEREX PHARMACEUTICALS INC.
Pharmaceutical compositions comprising a macromolecular pharmaceutical agent in mixed micellar form are disclosed. The mixed micelles are formed from an alkali metal alkyl sulfate, and at least three different micelle-forming compounds as described in the specification. Micelle size ranges between about 1 and 10 nanometers. Methods for making and using the compositions are also disclosed. A preferred method for administering the present composition is through the buccal region of the mouth.
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SEMI-REFINED CARRAGEENAN DENTIFRICE BINDER

(WO2001066073) 13.09.2001 A61K 8/73 SHEMBERG MARKETING CORPORATION
Also disclosed is a toothpaste binder composition comprising semi-refined carrageenan, such as semi-refined. kappa or semi-refined iota carrageenan, further comprising ultra low viscosity guar gum. Such a toothpaste binder composition is preferably comprised of about 5 % to about 10 % refined kappa-2/lambda carrageenan; about 40 % to about 50 % refined iota carrageenan; about 20 % to about 25 % semi-refined kappa and/or semi-refined iota carrageenan; about 10 % to about 20 % ultra low viscosity guar gum; and about 5 % to about 10 % standardizing agent; by dry weight.
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DEVICE FOR CAPTURING DUST IN THE LOADING OF CONCRETE MIXER TRUCKS

(WO2001064558) 07.09.2001 B01D 45/00 ESPINA FRUTOS, Juan Jos
The device comprises a container (1) with a mouth (4') to which the end of the conduit through which cement falls into the drum (3) of a concrete mixer truck is coupled, said container being fixed and having a trap door (6) for adapting the back part of said drum (3) so that the dust originating from the fall of the cement remains inside sad container (1). Part of the dust goes out through the conduit (9) to a common collector (10) while the other part is suctioned in through a suctioning head (2) formed by a truncated cone-shaped body, the biggest base thereof being coupled to the mouth (3') for loading the drum (3) and the smallest base leading to a conduit (13) that ends in the common collector (10). The dust is suctioned in from said co...
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SYSTEM CONSISTING OF A DENTAL CLEANING AGENT CONTAINING PROPELLANT GAS AND A DISPENSER

(WO2001062212) 30.08.2001 B65D 83/14 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to a system consisting of a dental cleaning agent containing tensides and propellants and a dispenser that holds said dental cleaning agent containing propellants, said dispenser having means for supplying and discharging the dental cleaning agent, comprising a manually operated discharge valve.
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DENTAL CLEANING AGENT CONTAINING PROPELLANT GAS

(WO2001062210) 30.08.2001 A47K 5/12 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to dental cleaning agents containing tensides, humectants and water, which are fed into a dispenser system together with a propellant gas or propellant gas mixture containing at least one component that boils at 9-35C at normal pressure, said dispenser system having a manually operated valve.
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DENTAL CLEANING AGENTS CONTAINING PROPELLANT GAS

(WO2001062209) 30.08.2001 A47K 5/12 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to dental cleaning agents containing polishing agents, humectants and tensides combined with liquid oils or wax components, which are fed into a dispenser system with propellant gases, said dispenser system having a valve.
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DENTAL MATERIAL PACKAGING

(WO2001062203) 30.08.2001 A61C 19/00 DENTSPLY INTERNATIONAL INC.
The invention provides a storage stable dental composition comprising a volatile organic solvent and a polymerizable material enclosed by a package, which includes a cover and a container made of a polymer such as a copolymer of a cycloolefin and an open chain olefin. In accordance with an embodiment of the invention is provided a stored packaged dental product by the process including: enclosing a dental composition in a package with at least a substantial portion of an injection molded polymer such as a thermoplastic copolymer of a cycloolefin and an open chain olefin, and storing the dental composition in the package for at least 1 week.
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PACKAGED APPLICATOR ASSEMBLY

(WO2001062177) 30.08.2001 A46B 11/00 3M INNOVATIVE PROPERTIES COMPANY
An applicator assembly includes an applicator having a tip and a cap initially extending over the tip and detachably connected to the applicator. The applicator includes a flexible portion that can be bent in an arc as the cap is detached from the applicator in order to enhance access to the application site when needed. In preferred embodiments, the tip is supplied with a quantity of composition such as dental composition, and as a result is especially advantageous for single patient use.
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DENTAL COMPOSITION WITH LIGHT STABILITY

(WO2001060322) 23.08.2001 A61K 6/083 DENTSPLY INTERNATIONAL INC.
Dental composition having an improved light and thermal stability, including a mixture of at least a polymerizable resin, at least a polymerizable monomer, at least a polymerization initiator and/or a sensitizer and stabilizer, and at least an organic and/or inorganic filler and pigments in a content of 0 to 90 percent and at least one of the stable radicals.
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TOOTHPASTE WITH DENTAL AGENT AND MICROBEADS

(WO2001058416) 16.08.2001 A61K 7/16 ALTICOR INC.
A formula for dental care products including a carrier, a first dental agent and microbeads including a second dental agent. One embodiment of a composition is a unique, three-pronged solution to the problem of dentinal hypersensitivity when the first agent and the second agent are the same. A dentifrice composition includes potassium nitrate. A portion of the potassium nitrate is included within microbeads to provide a longer-term, timed-release relief. Another portion of the potassium nitrate is freely available within the toothpaste. In addition, the microbeads physical block dentinal tubules to provide further relief. The microbeads may also contain other dental agents for other purposes related to oral hygiene or tooth care.
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TOOTHPASTE COMPOSITION

(WO2001058415) 16.08.2001 A63B 23/04 SHEMBERG MARKETING CORPORATION
Disclosed is a toothpaste composition comprising ultra low viscosity guar and carrageenan as a combination viscosity builder. In preferred embodiments of the toothpaste composition the combination viscosity builder comprises less than about 10 % of the toothpaste composition by weight, and more preferably, about 0.5 % to about 5 % of the toothpaste composition by weight. The low viscosity guar preferably comprises less than about 50 % of the combination viscosity builder by weight, and more preferably, about 20 % to about 30 % of the combination viscosity builder by weight. Also disclosed is a dry blend comprising about 20-30 % low viscosity guar, about 50-60 % iota-type carrageenan and about 20-30 % lambda-type carrageenan. The specificati...
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DENTAL HYGIENE TOOL

(WO2001058380) 16.08.2001 A61C 15/04 VALADEZ ESPINOSA, Armando
The invention concerns an improved dental hygiene tool that is used together with a dental floss. Said tool has an anatomic design and a new floss holding system that makes it possible to mount single, double or even triple flosses. The tool has an elliptical isometric cut handle with two identical opposite angles, said handle holding on its ends an off-center U-shaped fork at an ideal upward opposite angle thereby enabling easy access to the mouth with the purpose of achieving efficient and comfortable cleaning. The tool is formed by a single piece having four solid-state inserts made of antibacterial material for holding the floss, which facilitate maintenance and prevent the adherence of bacteria. The invention provides optimum access to...
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DENTAL INTERSTICE CLEANING DEVICE WITH AN ARTICULATED CLEANING TIP AND HANDLE

(WO2001058379) 16.08.2001 A61C 15/02 HEIN, Wolfram
The invention concerns a dental interstice cleaning device consisting of a handle and a cleaning tip hingedly connected thereto for flexible use in all regions of the mouth. The hinged connection is designed in such a way that the (flat, wedge-shaped) cleaning tip can move around two spatial axes in order to move the cleaning tip in the required positions relative to or in the dental interstices. The (vertical scrapping) cleaning motion, which is carried out around a third spatial axis, is blocked in the hinged connection so that said movement can be transmitted from the handle to the cleaning tip. To solve this problem, the cleaning tip (2) is seated perpendicularly in a circular cylinder (8) or is placed in a sphere (1), which in turn has...
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VACUUM SEALER FOR A BAG

(WO2001056887) 09.08.2001 B65B 31/00 SINGER, Alec
A vacuum sealer is disclosed which makes use of a flexible flap (24.2) secured along one of its edges to a base plate (12.2). The base plate (12.2) on which the bag (B) to be evacuated and sealed is placed has a vacuum port (16.2) in it so that air can be sucked out from between the base plate (12.2) and flap (24.2). A groove (36.2) is provided in the base plate (12.2). This assists in keeping the bag mouth from being sucked shut before evacuation is complete. An anvil (26.2) and a sealer bar (14.2) form a weld across the bag adjacent its open mouth after evacuation.
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METHOD FOR CLEANING AND STERILIZING DENTAL AND MEDICAL INSTRUMENTS

(WO2001056494) 09.08.2001 A61C 19/00 MOERS, John, W.
An improved method for cleaning and sterilizing medical and dental instruments (16) employs the use of a banding device (10) to segregate and hold together medical or dental instruments (16) after use in a particular procedure. The banded instruments (16) are then cleaned and sterilized. This method essentially eliminates the time and effort formerly required when unsegregated instruments were mixed with other instruments for cleaning and sterilization and then stored according to the particular procedure for which they are intended and/or according to the intended particular user thereof.
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HYBRID ADENO-RETROVIRAL VECTOR FOR THE TRANSFECTION OF CELLS

(WO2001055362) 02.08.2001 A61K 48/00 THE GOVERNEMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTEMENT OF HEALTH &HUMAN SERVICES, THE NATIONAL INSTITUTES OF HEALTH
An adenovirus, including adenoviral capsid proteins, and a replication-defective adenoviral vector that includes a 5" retroviral LTR nucleic acid sequence, a 3" retroviral LTR nucleic acid sequence, a nucleic acid sequence encoding a portion of a retroviral envelope protein adjacent to either the 5" LTR or the 3" LTR nucleic acid sequence, a retroviral packaging sequence and a nucleic acid sequence encoding a transgene located between the 5" LTR and the 3" LTR is provided. Host cells infected with this adenovirus are also provided. An adenoviral vector is provided that includes an adenoviral polynucleotide sequence comprising a nucleic acid encoding a transgene, a retroviral packaging signal, a 5" and a 3...
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DEVICE AND METHOD FOR CLEANING A SURFACE OF A ROTATING CYLINDER, SUCH AS A PLATE CYLINDER OF A PRINTING PRESS OR OTHER

(WO2001054909) 02.08.2001 B41F 23/00 FABIO PERINI S.P.A.
The device comprises a suction chamber (41) having a mouth facing toward the cylinder and a nozzle (44) which is associated with the suction chamber and by which a jet of a cleaning liquid is generated. At least a first drying chamber (45, 47) is also provided, associated with said suction chamber (41) and connected to a suction pipe (43).
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COMPOSITIONS AND METHODS FOR WHITENING AND DESENSITIZING TEETH

(WO2001054610) 02.08.2001 A61C 5/00 ULTRADENT PRODUCTS, INC.
Composition and methods which include a dental bleaching agent and potassium nitrate for enhanced whitening and reduced tooth sensitivity. The potassium nitrate both enhances the whiteness of teeth beyond the whitening effect of the dental agent and reduces or eliminates tooth sensitivity that would otherwise be caused by the bleaching agent. For prolonged treatment of teeth, lower quantities of potassium nitrate (e.g., 0.5 %) have actually been found to work better than larger quantities (e.g., 3 %). The dental compositions (40) may be applied directly to the person's teeth, or they may be loaded into a comfortable fitting, flexible, thin-walled dental tray (50) and placed over the person's teeth. In that case, the dental compositions (40)...
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TREATMENT FOR DRY MOUTH EMPLOYING CARBAMIDE PEROXIDE

(WO2001054499) 02.08.2001 A61K 31/327 MORGAN, Susan, Ann
A treatment for xerostomia, employing a composition having the active ingredient of carbamide peroxide. The carbamide peroxide compound contains urea and hydrogen peroxide. The hydrogen peroxide remains stable until the carbamide peroxide is applied to the mouth and contacts the water inherent therein. On contact, the hydrogen peroxide is freed from the urea, allowing the hydrogen peroxide to react within the mouth. The resulting chemical and mechanical reaction stimulates saliva within the mouth and thereby relieves the symptoms of xerostomia.
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METHODS OF USING A BEVERAGE COMPOSITION FOR TREATING DENTAL EROSION

(WO2001052796) 26.07.2001 A23L 2/02 THE PROCTER &GAMBLE COMPANY
The present invention is directed to a method of treating dental erosion comprising orally administering to a mammal (preferably, a human) a beverage composition having a pH of less than about 5; wherein the beverage composition comprises a compound having the structure (I), wherein n is an integer averaging from about 7 to about 100 and M, M' and M'' are each, independently, selected from the group consisting of sodium and potassium. The present invention is further directed to kits comprising the foregoing beverage composition and information that use of the beverage composition provides treatment against dental erosion.
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REDUCTION IN BACTERIAL COLONIZATION BY ADMINISTERING BACTERIOPHAGE COMPOSITIONS

(WO2001051066) 19.07.2001 A01N 63/00 INTRALYTIX, INC.
The present invention provides a method for reducing the risk of bacterial infection or sepsis in a susceptible patient by treating the susceptible patient with a pharmaceutical composition containing bacteriophage of one or more strains which produce lytic infections in pathogenic bacteria. Preferably, treatment of the patient reduces the level of colonization with pathogenic bacteria susceptible to the bacteriophage by at least one log. In a typical embodiment, the susceptible patient is an immunocompromised patient selected from the group consisting of leukemia patients, lymphoma patients, carcinoma patients, sarcoma patients, allogeneic transplant patients, congenital or acquired immunodeficiency patients, cystic fibrosis patients, and ...
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DENTAL COMPOSITIONS

(WO2001051012) 19.07.2001 A61K 8/04 THE BOOTS COMPANY PLC
An oral care composition comprising an effective amount of a therapeutic agent adsorbed onto nanospheres, together with orally acceptable diluents or carriers.
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POLYMERISABLE RESIN COMPOSITIONS FOR USE IN DENTISTRY

(WO2001050974) 19.07.2001 A61C 5/00 DENFOTEX LTD.
A polymerisable dental filling and sealing composition is provided which comprises a mixture of at least one resin containing on average at least two acrylate or methacrylate groups and a copolymerisable methacrylate or acrylate monomer, which has a low viscosity compared with said resin, the copolymerisable monomer being present in an amount such that the composition can be introduced by syringing into a cavity having a diameter of less than 1 mm.
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WARP RESISTANT ACCESS DOOR ASSEMBLY FOR A HIGH TEMPERATURE COMBUSTION CHAMBER

(WO2001050076) 12.07.2001 F23G 5/44 LARGENT, Thomas, R.
A warp resistant fuel feed door assembly (10) for use in injecting supplemental fuel into a high temperature combustion chamber such as a rotating cement kiln (16) without substantial loss of heat or combustion gases. The apparatus, which is positioned on the exterior side of a fuel passage (18) transecting the wall of a rotating kiln (16), opens to receive fuel and then seals during the balance of the rotation of the kiln. Warping, bearing fracture, shaft distortion and jamming due to exposure to extreme heat and cooling are minimized by the sectional construction of the doors (12a, 12b). The door includes a plate (22a, 22b) positioned over the mouth of the passage, a plurality of support arms (110, 112, 114, 116) attached to the plate and...
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METHOD FOR PLASTICIZING A NONWOVEN WITH POLYETHYLENE OR MOLTEN POLYPROPYLENE FOR THE MANUFACTURE OF DISPOSABLE GARMENTS USED AS BIBS AND FOR SURGICAL APPLICATIONS

(WO2001049913) 12.07.2001 A41H 43/00 ABDO MINA, Yamil, Alfredo
The invention relates to a method for plasticizing one or both surfaces of a nonwoven with polyethylene or polypropylene melted at a temperature of 400 C and stuck by cooling at a temperature of -4 C by means of contact with the pressure cylinders (Fig. 1) at a low temperature (-4 C). The displacement speed of the fabric is 15 m/min and the force of impregnation is 210 kg. force/cm?2. The resulting nonwoven, whose fiber composition consists of polyester-rayon mixtures (ideally 50 %- 50 %), is a light fabric which is resistant to traction and tearing forces and totally impervious to water, blood, vapor and air and has a surface that absorbs liquids and moderately viscous substances, thereby making it suitable for the manufacture of d...
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TEMPORARY DENTAL CEMENT COMPOSITIONS AND RELATED METHODS AND SYSTEMS

(WO2001049251) 12.07.2001 A61K 6/083 ULTRADENT PRODUCTS, INC.
A temporary dental cement composition temporarily affixes a dental prosthesis or appliance to a tooth or other dental substrate. The dental cement includes a mixture of: (i) an ion leaching agent; (ii) polycarboxylic acid; (iii) sugar; and (iv) water. The sugar is added in a sufficient amount that the ion leaching agent and polycarboxylic acid form a hardenable adhesive having an adhesive matrix which forms a relatively weak, temporary bond, as opposed to a permanent bond. The temporary cement composition is compatible with subsequent deposition of typical bonding materials, such as resin luting agents as well as non-resin permanent cements.
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BUCCO-DENTAL HYGIENE

(WO2001049241) 12.07.2001 A61K 8/66 DANA, Jean-Dominique
The invention concerns a method for transforming food sugars, which acts in two ways: directly and indirectly. Said method is characterised in that the main direct action consists in inhibiting glycolysis by transforming the cariogenic polyoses into non-cariogenic polyols (for example, sorbitol); the indirect action consists in the use of products derived from the polyose degradation as substrates by the inventive enzymatic system so as to reinforce prevention of plaque formation, through five mechanisms: stimulating saliva flux with the polyols; reinforcing the saliva antibacterial power by activating the physiological lactoperoxidase/hypothiocyanate system with hydrogen peroxide; decreasing the number and pathogenicity of the bacterial en...
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DISPENSER WITH BIASED COVER

(WO2001047590) 05.07.2001 A61M 15/00 GLAXO GROUP LIMITED
There is provided a dispenser comprising a body for receipt of a carrier for a composition; an exit channel definable by the body for passage of the composition to a user; a cover for the exit channel reversibly movable between a storage position in which the cover fully protects the exit channel, to an in-use position wherein the exit channel is exposed. Biasing means act on the cover when the cover is not in the in-use or storage positions, to bias the cover towards either the in-use position or the storage position.
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TIP FOR DENTAL FLOSSING DEVICE

(WO2001045583) 28.06.2001 A61C 15/00 WATER PIK, INC.
A flossing tip (22) for a power dental flossing device (20) is elongated and includes a base portion (74), a central portion (76) having a generally rectangular cross-section, and an enlarged end portion (70) including a disk shape (72). The tip (22) is compressible. The base portion (74) supports the tip (22) when the tip (22) is coupled to the dental flossing device (20). The central portion (76) couples the base portion (74) to the end portion (70). The end portion (70) is inserted between a pair of adjacent teeth (24A, 24B) of a user and helps guide and orient the tip (22) between adjacent teeth (24A, 24B). When in use, the rectangular cross-section of the tip (22) provides multiple points of contact against a tooth for cleaning and als...
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PHOTOINITIATOR SYSTEM WITH ACYLPHOSPHINE OXIDE INITIATORS

(WO2001044873) 21.06.2001 A61K 6/087 S &C POLYMER SILICON- UND COMPOSITE SPEZIALITTEN GMBH
A visible light photopolymerizable composition comprising a) an aryliodonium salt and b) an acylphosphine oxide compound. These compositions can be used together with an opoxide resin as a dental composition.
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PHOTOINITIATOR SYSTEM WITH TITANOCENE INITIATORS

(WO2001044343) 21.06.2001 A61K 6/087 S &C POLYMER SILICON- UND COMPOSITE SPEZIALITTEN GMBH
A visible light photopolymerizable composition comprising a) an aryliodonium salt and b) a titanocene derivate. These compositions can be used together with an epoxide resin as a dental composition.
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TOOTHBRUSH

(WO2001043581) 21.06.2001 A46B 5/00 GLAXOSMITHKLINE CONSUMER HEALTHCARE GMBH &CO KG
A dental cleaning implement such as a toothbrush, having longitudinally disposed first and second parts flexibly joined together. Between the first and second parts is a rotatable member (18) such that when the implement bends the first parts adjacent to the member bear upon the member. The rotatable member has circumferentially disposed relatively softer and harder regions, so that as the member is rotated the parts can be caused to bear compressibly upon selected softer or harder regions.
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TOOTHBRUSH

(WO2001043580) 21.06.2001 A46B 5/00 GLAXOSMITHKLINE CONSUMER HEALTHCARE GmbH &Co KG
A toothbrush having a head which carries a dental cleaning tool, and a grip handle, the head and handle being disposed along a longitudinal head-handle axis, the toothbrush having a resiliently flexible structure which can resiliently bend under the action of toothbrushing pressure and having adjustment means comprising a longitudinally moveable stiffening member (17) which can be moved longitudinally into greater or lesser engagement with the resiliently flexible structure.
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COMPOSITIONS FOR TREATING ABNORMALITIES IN GLOMERULAR FILTRATION, PATENT DUCTUS ARTERIOSUS AND OSTEOPOROSIS

(WO2001042281) 14.06.2001 A61K 38/00 HPITAL SAINTE-JUSTINE
The present invention relates to a composition of matter comprising novel prostaglandin E2 receptor antagonists, and their use in treatments for regulating the fluid filtration in the kidney, preventing bone mineral loss in osteoporosis and dental disease and additionally, closure of ductus arteriosus (DA) in premature infants or fetal animals. Additionally, the compositions include linear peptides, peptide analogs, and peptidomimetics.
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SELF CURING CEMENTS

(WO2001041713) 14.06.2001 A61F 2/46 ABONETICS 2000 LIMITED
A composition, for use in a dental or bone cement precursor composition, which comprises one or more compounds of general structure (I), wherein R1? is H, methyl, ethyl, propyl or isopropyl, n = 1, 2, 3 or 4, R2? is a side chain having general structure (A), wherein a = 4 to 16, b = 0 or 1, c = 0 or 1, d = 0 or 1, and wherein the total number of carbon atoms in the side chain R2? is not greater than 17 and one or more free radical activators.
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TONGUE CLEANING DEVICE IN THE FORM OF A SCRAPER

(WO2001039674) 07.06.2001 A61B 17/24 LE GOFF, Pierre, J.
The invention concerns an object for cleaning the tongue, which is indispensable for perfect bucco-dental hygiene and pure breath. The use of said object enables to eliminate various bacterial populations, the remains of chewing and tobacco smoking, the residual cells of plaque, dental caries and gum inflammation. The shape is specially designed to obtain maximum tongue-scraping efficiency and to avoid ill-timed swallowing. The material is carefully selected. The resulting object consists of a solid semi-ovate cup (1) bearing a thin scraper (3) extended by a handle providing easy handling, all in one single piece.
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ADHESIVE COMPOSITION

(WO2001038449) 31.05.2001 A61K 6/00 KURARAY CO., LTD.
An adhesive composition which comprises (a) a polymerizable monomer having an acid group, (b) a polymerizable monomer represented by general formula (I) [wherein R?1 represents hydrogen or methyl; R?2 represents halogeno, hydroxy, mercapto, amino, or a group represented by -O-R?3-OH (R?3 represents C6-25? alkylene); and Y represents oxygen or sulfur], and (c) a hydrophilic polymerizable monomer and in which the ratio of the amount of the polymerizable monomer (b) to that of the polymerizable monomer having an acid group (a) is from 0.001 to 0.5 by weight. The adhesive composition is suitable for use in bonding a hard tissue to a resin material in the medical and dental fields.
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TOOTHPASTE

(WO2001037797) 31.05.2001 A61K 8/26 ALCAN INTERNATIONAL LIMITED
There is disclosed a toothpaste comprising as an abrasive an alumina in the form of particles having d10? below 3.5$g(m)m, d50? below 1.0$g(m)m and a specific surface area below 6m?2/g.
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DENTAL APPARATUS FOR RECORDING THE INTERDENTAL RELATIONSHIP OF INTERIOR TEETH

(WO2001037755) 31.05.2001 A61C 9/00 SEGAL, Alan, Julian
Dental apparatus for recording the interdental relationship of anterior teeth has an open frame and a handle. A bite tray (9) is secured within the frame so that impression material applied to the bite tray can be readily manipulated between a patient's anterior teeth. The frame may be formed from upper and lower pivotally interconnected arcuate parts (2, 5) and the bite tray (9) has an arcuate segmental body of flexible perforated supporting material with a stiffened strip (10) around its curved periphery. This strip (10) is clamped between confronting faces (15, 16) of the parts (2, 5) and is located in position by engagement of pins (8) on the lower part (2) with holes (11) in the strip (10).
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CPR MANIKIN WITH OPTIONAL AUTOMATIC EXTERNAL DEFIBRILLATION

(WO2001037243) 25.05.2001 G09B 23/32 VITAL SIGNS, INC.
Apparatus for practicing cardiopulmonary resuscitation (CPR) including a torso, a breast plate, a lung, and a hollow head including a mouth means, the breast plate is mounted pivotally to the torso, the lung resides intermediate the torso and the breast plate and is mounted to the torso and extends into the hollow head member and a second head member mounted to the first head member for sliding arcuate movement with respect thereto to perform jaw thrusts in the practice of CPR. Apparatus simulating the human head. Stackable torsos with breast plates mounted thereto and stackable head members each comprising a portion of a head.
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COMBINATION TOOTHBRUSH AND TOOTHPASTE DISPENSER

(WO2001036217) 25.05.2001 A46B 5/00 ROSENBERG, Dorothy
Disclosed is a combination toothbrush and toothpaste dispenser (10). The toothpaste dispenser has a top and a compressible container (32) located therein. The container has a top (32a) and a bottom (32b), and toothpaste (27) located therein. The toothbrush includes a head portion (18) which has a plurality of bristles (20) extending therefrom and at least one hole (26) extending thereinto. The toothbrush also includes a stem portion (22) having a channel (24) extending therethrough. The channel has first and second opposing ends. The first end (22a) is in fluid communication with the at least one hole and the second end (22b) is in fluid communication with the top of the container. The toothbrush is reciprocally mounted to the toothpaste di...
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TEETH WHITENING PRODUCT

(WO2001035919) 25.05.2001 A61K 8/22 UNIVERSITAT DE LES ILLES BALEARS
The invention relates to a teeth whitening product containing accessory components, in addition to a teeth whitening compound and peroxidase as a combined product that is used simultaneously, separately or gradually over time. According to a preferred embodiment, the whitening compound is hydrogen peroxide or a hydrogen peroxide precursor. The product is useful for whitening teeth and can be used as a dentrifice, collutory or dental treatments.
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TIP FOR DENTAL FLOSSING DEVICE

(WO2001035852) 25.05.2001 A61C 1/07 WATER PIK, INC.
A flossing tip (22) for a power dental flossing device (20). The tip (22) is elongated and includes a base portion (30), a central portion (32) having a generally rectangular cross-section, and an end portion (34). The base portion (30) supports the tip (22) when the tip (22) is coupled to the dental flossing device (20). The central portion (32) couples the base portion (30) to the end portion (34). The end portion (34) is inserted between a pair of adjacent teeth (24A, 24B) of a user, and helps guide and orient the tip (22) between the adjacent teeth. When in use, the rectangular cross-section of the tip (22) provides multiple points of contact against a tooth for cleaning, and also helps maintain the tip (22) in proper orientation with r...
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ULTRASONIC APPARATUS FOR DECONTAMINATION

(WO2001034212) 17.05.2001 A61L 2/025 CARTER, Stephen, Douglas
An apparatus and associated method for decontaminating contaminated matter, such as an object or substance, with ultrasonic transient cavitation is disclosed. The apparatus comprises a container for containing a contaminated object, a pressure source for pressurizing the container to a predetermined pressure, a vibration source operably connected to the container, and a cleaning solution comprising a predetermined concentration of a volatile substance. The presence of the volatile substance in the cleaning solution, along with the pressurization and vibration thereof, enhances the effect of ultrasonic transient cavitation and improves decontamination of the contaminated matter. An associated method of decontaminating contaminated matter fur...
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LIQUID DELIVERY DEVICES

(WO2001032995) 10.05.2001 E03D 9/03 JEYES GROUP LIMITED
A liquid delivery device is particularly suited for dosing a toilet bowl with cleaning agents. Liquid from a reservoir (10) flows through an inner sleeve (34) of a connector (24) into a cup (18) until the liquid level reaches the mouth (60) of the inner sleeve (34). Web (32) is perforated so that the space (14) in cup (18) is open to atmosphere. Liquid is drawn from the cup (18) by a capillary (46) formed between the wall of cup (18) and the connector (24) and delivered to a porous pad (6). Flushwater runs over pad (6) and supporting plate (8) to disperse the liquid into a toilet bowl.
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FILTER MASK

(WO2001032265) 10.05.2001 A62B 18/08 XCAPER, INDUSTRIES, LLC
A filter mask (10) is provided for use in environments of smoke and toxic gas which includes a filter element (12) having a filling of shiftable bodies (24) coated with a flowable, aloe vera extract having a gel-like viscosity and a retainer (14) for holding the filter element (12) over the mouth and nose of the wearer. The coating has a pH level which is alkaline which aids in the reduction of toxic gases such as hydrogen cyanide, hydrogen chloride and acrolein inhaled by the wearer. The filter element (12) is preferably replacably mounted to the retainer (14) and may be provided as a bag-like flexible fabric container adapted to shift so as to conform to the face of the wearer. The filter element (12) itself is adaptable to a variety of d...
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PLUNGER FOR A PRESSING FURNACE

(WO2001032094) 10.05.2001 A61C 13/20 JENERIC/PENTRON INCORPORATED
A disposable plunger for use in a pressing furnace for the fabrication of dental restorations. The plunger is fabricated of a partially sintered ceramic material. The plunger is fabricated by known casting methods. The mold used for making the plunger can be supplied by a manufacturer of molds or can be easily made by using an alumina or similar plunger as a model. Laborious cleaning and grinding are not required with plungers herein described. Cracking problems that occur with prior art plungers are decreased, if not completely eliminated.
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ACTIVE SUBSTANCE DISPENSER FOR WATER CLOSET BOWL

(WO2001031128) 03.05.2001 E03D 9/03 RE.LE.VI. S.P.A.
The dispenser comprises a container (11) for containing the active substance (R) in the fluid state and provided with an exit mouth (12), and a support means (20) for supporting said container (11) with its mouth (12) facing downwards. A swinging plate (21) is joined to the support means (20) by an elastic hinge means (22) which enables the plate (21) to swing between an upper normal position (A) in which the plate (21) is in contact with and closes the mouth (12) of the container (11), and a lower position (B) in which the plate (21) is spaced from the mouth (12) of the container (11) and receives substance (R) leaving said mouth (12); the elastic hinge means (22) is such as to enable the plate (21) to flex downwards into its lower positio...
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COMPOSITION FOR DENTISTRY COMPRISING AN ESSENTIAL OIL

(WO2001030303) 03.05.2001 A61K 6/00 DAKOTA DENTAL DEVELOPMENT, INC.
The present invention provides non-metallic compositions that are useful to repair, restore, adhere to, or protect, the surface of a tooth and that harden in the mouth to form substantially permanent features therein or to adhere fixtures to the surface of a tooth in a substantially permanent manner. The compositions comprise an amount of an essential oil effective to alter the sensory properties, i.e. the taste, a smell, of the composition and that desirably imparts a pleasant taste and/or order. The essential oil further advantageously provides the composition, once hardened in the mouth, with a surface more hydrophobic than a corresponding conventional composition, thereby inhibiting the deposition or formation of bacterial plaque. Also ...
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DENTAL COMPOSITIONS

(WO2001030302) 03.05.2001 A61K 6/00 KERR CORPORATION
A two part composition for sealing and/or filling root canals. One or more elastomeric (meth)acrylate oligomers are mixed with one or more diluent comonomers, one or more radiopaque fillers and one or more polymerization initiator systems. One or more antimicrobial agents may also be included in the composition. The components are mixed, undergo a setting reaction and are subsequently cured. In use, the composition is easily removed from the tooth structure if rework is needed, yet provides a tight and effective seal in the root canal. The composition also has a desirable flowable consistency and exhibits good adhesiveness with a tooth substrate.
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FLAVORED ORTHODONTIC ADHESIVE

(WO2001030301) 03.05.2001 A61K 6/00 DAKOTA DENTAL DEVELOPMENT, INC.
Compositions for conditioning a tooth surface prior to the application of a dental materials which will desirably form a substantially permanent bond with the conditioned tooth surface are provided. The conditioning compositions comprise an amount of an essential oil effective to alter the sensory properties, i.e. the taste, a smell, of the conditioning composition and that desirably imparts a more pleasing taste and/or odor. Also provided are methods of using the conditioning composition to prepare a tooth surface for the application of a free radically polymerizable dental material and for treating a tooth by forming a substantially permanent bond with a free radically polymerizable dental material.
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BRUSH

(WO2001030198) 03.05.2001 A45D 27/46 RICHTER CORPORATION
A brush includes a handle (11) made of an insulator and a large number of filaments (FM) on the head of the handle (11). On the head of the handle (11), an anode (12) made of a noble metal, carbon, and a cathode (13) made of a base metal, magnesium are installed. The anode and cathode (12, 13) are insulated from each other. The brush produces a bactericidal or sterilizing effect and cleans the mouth without any dentifrice.
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CLOSURE CAP MADE OF PLASTICS MATERIAL

(WO2001026989) 19.04.2001 B65D 41/04 CROWN CORK &SEAL TECHNOLOGIES CORPORATION
A closure cap made of plastics material for closing a container mouth (30) consists essentially of a top plate (2) and a skirt (4) extending from the edge (3) of the top plate (2). The closure cap (1) is provided with a sealing lip (5), which has a root section (6) and a sealing section (7), between which a materiel weakening (8, 9, 8) is arranged. In an improvement, the sealing section (35) has an actuating part (39), which engages the container rim (33) during capping, and a sealing part (38) which contacts a sealing surface (32) on the container mouth (30) to form the seal.
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PYRIDINIUM DERIVATIVES FOR THE TREATMENT OF DIABETIC AND AGING-RELATED VASCULAR COMPLICATIONS

(WO2001025209) 12.04.2001 C07D 213/82 TORRENT PHARMACEUTICALS LTD
The invention discloses compounds of the pyridinium series useful for the management of diabetes and aging-related vascular complications, and particularly in the treatment of complications of diabetes mellitus and other aging-related conditions including kidney disease, nerve damage, atherosclerosis, retinopathy, dermatological conditions and discoloration of teeth by breaking preformed AGE, of general formula (I), or pharmaceutically acceptable salts thereof, wherein, R?1, R?2 and X are as defined in the specification. The invention also discloses method of preparation of the compounds of the series and pharmaceutical composition having one or more compounds as defined above as active ingredients. The invention further discloses a met...
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PYRIDINIUM DERIVATIVES FOR THE MANAGEMENT OF AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF

(WO2001025208) 12.04.2001 A61K 31/4425 SANKARANARAYANAN, Alangudi
The invention discloses novel compounds of the pyridinium series useful for the management of diabetes and aging-related vascular complications, including kidney disease, nerve damage, atherosclerosis, retinopathy, dermatological disorders and discoloration of teeth, by breaking preformed AGE, of general formula (I), or pharmaceutically acceptable salts thereof, wherein, R1?, R2?, R3?, X and m are as defined in the specification. The invention also discloses, method for preparation of the novel compounds of the series and pharmaceutical composition having one or more compounds as defined above as active ingredients. The invention further discloses a method of treatment of a diabetic patient by administering the compounds as defined ab...
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METHOD FOR CURING A DENTAL COMPOSITION USING A LIGHT EMITTING DIODE

(WO2001024724) 12.04.2001 A61C 5/00 NEW PHOTONICS, LLC
A dental composition curing method and device (10) for exposing a dental composition to a beam of radiation (26) emitted by a light-emitting-diode (LED) (14) positioned proximate the composition, LED radiation being more efficient than the conventional use of filtered white light. The device also includes a handle (12) and power supply (24).
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MODIFIED ION SOURCE TARGETS FOR USE IN LIQUID MALDI MS

(WO2001023863) 05.04.2001 H01J 49/04 LUDWIG INSTITUTE FOR CANCER RESEARCH
The present invention pertains to modified ion source targets suitable for use with liquid matrices (e.g., glycerol and lactic acid) in liquid matrix-assisted laser desorption/ionisation (MALDI) methods, as used, for example, in infrared (IR) liquid MALDI mass spectrometry (MS), preferably using time of flight (TOF) instruments. The modified targets comprise (a) a target plate (3) adapted for use in an ion source, said plate having an outward facing surface; and (b) a shielded sample cavity comprising : (i) a sample cavity (4) formed in said outward facing surface, said cavity having a sample cavity mouth and a sample cavity volume, and adapted to receive a liquid sample (5); and (ii) a perforated sample cavity shield (1), said shield cover...
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MEANS FOR USE BETWEEN A DENTAL PROSTHESIS AND A JAW/PALATE

(WO2001021093) 29.03.2001 A61C 13/07 GOVAERT, Frederik, Johan
The invention relates to a means for use between a dental prosthesis and a jaw/palate. The means according to the invention is characterized in that the means is a thin, flexible film made from a non-toxic material such as, for example, plastic. According to a preferred embodiment according to the invention the film is double-walled and the film is filled with a non-toxic fluid such as, for example, air, gel, oil, fat, wax (e.g. beeswax), emulsion, paste, a powder suspended in liquid, or a mixture of these.
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METHOD FOR APPLYING A DENTAL COMPOSITION TO TOOTH STRUCTURE

(WO2001020980) 29.03.2001 A61C 5/06 3M INNOVATIVE PROPERTIES COMPANY
A method of applying a dental composition to tooth structure of a dental patient includes the act of providing an applicator having an empty chamber at least partially surrounded by flexible wall portions. A tip portion of the applicator is placed into a bulkcontainer having a quantity of dental composition, and the wall portions are squeezed together. When the wall portions are released, a portion of the dental composition is drawn into the chamber by suction. The wall portions are then squeezed together once the tip portion of the applicator has been placed next to tooth structure of a dental patient in order to dispense at least a portion of the dental composition directly onto the tooth structure. Since a sufficient amount of compositio...
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APPARATUS AND METHOD FOR FILLING AND CLOSING A CONTAINER IN TWO STAGES

(WO2001019717) 22.03.2001 B65B 55/24 SEARLE, Matthew, John
A wide mouthed container (2) filled with beer (20) has a first closure member (12) applied thereto and held in position. The container is then moved along the filling line to a cleaning station at which the exterior thereof is subjected to high pressure jets of water to clean any contaminants therefrom. After drying, a second closure member (14) is screwed over the first closure member (12) to seal the container. In this manner, it is ensured that there are no contaminants on the exterior of the container near the mouth opening so that it is safe to drink from the container after opening.
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THE USE OF BACTERIAL PHAGE ASSOCIATED LYSING ENZYMES FOR THE PROPHYLACTIC AND THERAPEUTIC TREATMENT OF VARIOUS ILLNESSES

(WO2001019385) 22.03.2001 A61K 38/46 NEW HORIZONS DIAGNOSTICS, INC.
A method for the prophylactic and therapeutic treatment of bacterial infections is disclosed which comprises the treatment of an individual with an effective amount of a modified version of a lytic enzyme produced by a bacteria infected with a bacteriophage specific for said bacteria wherein said modified version of said at least one lytic enzyme is selected from the group consisting of shuffled lytic enzymes, chimeric lytic enzymes, wherein the lytic enzyme is in an environment having a pH which allows for activity of said lytic enzyme; and a carrier for delivering said lytic enzyme. Additionally, a holin enzyme for puncturing the membrane may be included in the composition. This method, and composition can be used for the treatment of upp...
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HERBAL COMPOSITIONS FOR ITCHY OR INFECTED SKIN

(WO2001017539) 15.03.2001 A61P 17/00 SHAH, Eladevi
The present invention relates to the preparation and use of compositions for the treatment of skin disorders itchy and/or infected skin such as impetigo, acne (on face, forehead scalp and on the back of the body) and fungal infection of skin and nails. Whether the infection may be acute or chronic or sub-acute or acute on chronic. As well as for the promotion of non carrier state of the human beings and animals from some pathogenic bacteria such as staphylococci. The compositions are based on extracts from the plants Cassia tora, Centratherum anthelminticum and/or Melia azadirachta. A variety of other herbal extracts may be included and the composition may take the form of a freeze dried or a spray dried powder or presence of this in a crea...
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AUTOPOLYMERIZING PROSTHETICAL AND REBASE MATERIALS AND THEIR USE

(WO2001017482) 15.03.2001 A61K 6/083 VOCO GMBH
The invention relates to autopolymerizing prosthetical and/or rebase materials. Said autopolymerizing materials contain pearl polymers and polymerizable methacrylate monomers, except for monomethacrylates. The pearl polymers do not swell in the presence of the methacrylate monomers and therefore do not influence the viscosity of the dental composition. The non-swelling pearl polymers produced according to the invention therefore make it possible to provide autopolymerizing prosthetical and/or rebase materials that can be stored as paste/paste systems.
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INCREASED PEROXIDE CONTENT TOOTH BLEACHING GEL

(WO2001017481) 15.03.2001 A61K 8/19 DISCUS DENTAL, INC.
A two-component tooth whitening system which incorporates an increased peroxide content, wherein the components are adapted to be mixed and applied to the teeth from a dental bleaching tray is provided. A first component includes both carbamide peroxide and hydrogen peroxide and a second component comprises an orally compatible activator gel.
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TOOTHBRUSH FOR THE COMPLETE CLEANING OF THE MOUTH

(WO2001017433) 15.03.2001 A46B 5/00 DE LA PEA LEVY, Ral
The invention relates to a toothbrush for the complete cleaning of the mouth, through incorporating a tongue-cleaner at the back of the toothbrush head or in any other part of the handle; the incorporation of a part made of any rubber component and placed longitudinally between the bristles may clean and massage the gums; and a toothbrush head which can be dismounted from the handle so that it can be discarded. The object of this invention is that, when brushing the teeth, the user may, with the same instrument and in a simple way, clean completely the tongue thereby eliminating one of the main causes of halitosis and various bucco-pharyngeal infections, and at the same time clean and massage the gums in order to strengthen them and to avoi...
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COMPOSITION FOR MAINTENANCE OF BONE OR DENTAL HEALTH OR TREATMENT OF BONE OR DENTAL DISORDERS

(WO2001015715) 08.03.2001 A61K 35/74 SOCIETE DES PRODUITS NESTLE S.A.
The application relates to a composition for maintenance of bone or dental health or treatment of bone or dental disorders, a method of preparing the composition, the composition for use as a medicament and a method of treatment. A preferred embodiment of the composition comprises La10 bacterium, vitamin D and calcium.
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APPLICATION DEVICE

(WO2001015623) 08.03.2001 A61C 19/06 JANSE VAN RENSBURG, Frederick, Cornelius
A dental applicator for applying a medicament and/or substance or composition to a substrate, includes a capillary portion, the internal diameter of which can be selected in relation to the volume of medicament and/or a substance or composition to be applied. The capillary portion has, at a first end, an applicator tip shaped and dimensioned so as to administer individual drops of fluid and at a second end has attached to it, or forming an integral part of the capillary portion, a means for drawing fluid into the capillary portion and, optionally, for subsequently forcing said fluid out of the capillary portion at its first end.
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TOOTHBRUSH, TOOTHPASTE TUBE AND SOLID SOAP KEEPING SET

(WO2001015586) 08.03.2001 A47K 1/09 HAN, Moon-Key
The toothbrush, toothpaste tube and solid soap keeping set in which a toothbrush, a toothpaste tube and solid soap used in a bathroom are installed on one equipment die, is constructed by combining an equipment die having a plurality of hanger parts formed on a front face thereof and a plurality of stick-in flutes formed on the top thereof, a toothbrush, a toothpaste tube and solid soap, wherein the toothbrush, the toothpaste tube and the solid soap respectively have a ring part hanging on the hanger part and an insertion shaft inserted into the stick-in flute, thus, the keeping set can be conveniently used by hanging it on wall or setting it on a flat part of the bathroom.
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TANK, ESPECIALLY FIRE EXTINGUISHER CYLINDER, PROVIDED WITH INNER CORROSION PROTECTION, AND PROCESS FOR PRODUCING IT

(WO2001014212) 01.03.2001 F17C 1/10 SZ&Odblac;CS, Istvn
Tank, especially fire extinguisher cylinder, provided with inner corrosion protection, having a metal tank, preferably a metal tank made of steel plate and an inner surface made of corrosion resistant material bordering the inner space of the tank, the inner surface made of corrosion resistant material is the inner surface of an insertion tank made of thermoplastic synthetic material, especially polyethylene terephthalate, which insertion tank seats to the inner surface of the metal tank and lines the mouth opening of the metal tank.
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DENTAL FLOSS DISPENSER

(WO2001013816) 01.03.2001 A61C 15/04 VAN DER WESTHUIZEN, Lourens, Marthinus
A dental floss dispenser (1) is provided which can be fitted long term to the screw threaded outlet (11) from a toothpaste tube (2) whilst permitting toothpaste to be squeezed out of the tube without removing the dispenser therefrom. The dispenser comprises a body (3) defining an annular cavity (6) for receiving a spool (8) of dental floss such that the spool is rotatable about a tubular passage (9) passing axially through the body and defining the inner extremity of the annular cavity. The tubular passage has formed in one end region (the inlet end) a screw threaded socket (10) compatible with a screw threaded outlet (11) from the toothpaste tube. The opposite end (the outlet end) of the tubular passage cooperates with a releasable closure...
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A GLASS COMPOSITION

(WO2001012567) 22.02.2001 A61K 6/06 TELDENT LIMITED
A glass composition having the general empirical formula given below, expressed in weight percent of the element: P: 16-24, F: 5-30, O: 20-40 and at least one of Na, K, Li or Al in an amount up to a total of 40 wt. % and optionally, up to 5 wt. % of boron and/or silica. The composition may be used for the treatment and/or prevention of dental caries by providing a slow fluoride releasing device that may be attached to a tooth to release fluoride into the saliva of an individual.
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DENTAL COMPOSITIONS COMPRISING DEGRADABLE POLYMERS

(WO2001012129) 22.02.2001 A61K 6/00 JENERIC/PENTRON INCORPORATED
Curable compositions comprising degradable macromonomers having one or more terminal acrylate or methacrylate functionality, a curing composition, and optionally one or more polymerizable acrylate or methacrylate comonomers. Degradable macromonomers are manufactured from cyclic monomers with compounds having acrylate or methacrylate functionality. Depending on their use, the degradable macromonomer compositions further comprise one or more organic or inorganic fillers, including a calcium-based compound and/or a radiopacity-imparting agent. The compositions are particularly suitable for root canal sealants, implants, and pulp capping materials.
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DENTAL FLOSS DEVICE

(WO2001012100) 22.02.2001 A61C 15/04 WESTONE PRODUCTS LIMITED
A dental floss device has a length (7) of dental floss which comprises a plurality of threads organised in an interlaced array and a frame member (3, 4) carrying the length of dental floss. The length of dental floss is anchored, at at least one end, to the frame member by mechanical interlocking of material of said frame member with said threads. At least one of the threads of the floss is a thread of PTFE. One or more threads of other material may be included. The floss may be a braided product.
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INVERTED PRESSURE VESSEL WITH HORIZONTAL THROUGH LOADING

(WO2001010733) 15.02.2001 B01J 3/00 S. C. FLUIDS, INC.
A pressure vessel (1) for use in production processes requiring elevating and ranging of temperatures and pressures during the process cycle, readily adaptable to production line operation, suitable for wafer processing in the semiconductor industry and for other industries and processes. The pressure vessel (1) is configured within an open support frame (6) with a stationary, preferably inverted, orientation. The cover or closing plate (2) is vertically movable towards the mouth of the pressure vessel (1) and functions as the platform by which the object under process is transferred into the vessel (1). The moving and locking mechanism for the cover (2) is isolated and shielded from the process environment.
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STABLE HYDROGENATED LUPULONE ANTIBACTERIAL ORAL COMPOSITIONS

(WO2001010401) 15.02.2001 A61P 1/02 COLGATE-PALMOLIVE COMPANY
A stable antibacterial oral composition containing a hydrogenated lupulone and an anionic surfactant.
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DENTAL LASER SCALING DEVICE AND METHOD

(WO2001010327) 15.02.2001 A61C 1/00 CERAMOPTEC INDUSTRIES, INC.
A dental scaling device (1) is described that combines a typical scaling procedure with laser treatment. Mechanical, ultrasound or water jet scaling devices are examples of devices that can be combined with a laser source (2) to provide an improved dental instrument. This device allows teeth to not only be cleaned, but also to have harmful bacteria destroyed at the same time. This device can also be used for photodynamic therapy (PDT) in conjunction with other dental cleaning and scaling treatments.
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DENTIFRICE COMPOSITIONS

(WO2001007000) 01.02.2001 A61K 8/41 FRESH BREATH LIMITED
The present invention relates to a dentifrice composition comprising first and second constituents susceptible to inter-reaction with one another, wherein said constituents are in admixture with one another but at least one of said constituents is in an activity resistant particle form that resists such inter-reaction until the composition is used.
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CUTLERY WITH HYGIENIC DISPOSABLE MEMBRANE

(WO2001006899) 01.02.2001 A47G 21/02 DE BELLIS, Domenico
This invention consists of a piece of cutlery formed by a supporting body (1, 2) and a membrane, having the shape of a fork or spoon, which covers its upper part (2). It permits to get a greater hygiene, as the metal body (1, 2) of the cutlery never directly touch the food or one's mouth, it facilitates cleaning operations and it's particularly useful if used in canteens and public places.
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PROTECTOR FOR CATHETERS OF CLINICAL USE

(WO2001005461) 25.01.2001 A61M 25/00 MARTINEZ PEREZ, Teresa
The protector is comprised of a bag which is made of an appropriate sterile material in order to form a bedding for the catheter and act as a barrier against environmental microorganisms. The bag is adapted to house internally any type of catheter and incorporates at the vicinity of its mouth an adhesive strip as an extension of its front face. The strip constitutes a means for fixing the protector to the patient body as well as a means for closing and sealing the catheter bag. Said strip is a pressure adhesive strip comprising wax-treated, silicone-treated or similar protection paper sheets which can be removed for the fixing thereof to the patient body.
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USE OF A FATTY DERIVATIVE FOR THE TREATMENT OF EXTERNAL SECRETIONDISORDERS

(WO2001005388) 25.01.2001 A61K 9/00 SUCAMPO, A.G.
Disclosed is a composition for treatment of external secretion disorders comprising, as an active ingredient a fatty acid derivative. The composition of the present invention is useful for treatment of at least one condition selected from hypolacrimation including disorder of basal tear secretion, dry-eye syndrome, hyposalivation and dry-mouth syndrome.
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TASTE MASKED PHARMACEUTICAL LIQUID FORMULATIONS

(WO2001003698) 18.01.2001 A61K 9/00 ORTHO-MCNEIL PHARMACEUTICAL, INC.
A liquid composition for oral administration comprising a pharmaceutically active medicament coated with a taste masking effective amount of a polymer blend of (a) dimethylaminoethyl methacrylate and neutral methacrylic acid ester (MM/MAE) and (b) a cellulose ester, in an aqueous vehicle, wherein the polymer weight ratio of the cellulose ester to the MM/MAE is about 40:60 to about 90:10, preferably about 60:40. The liquid composition utilizes a 'reverse enteric coating' which is soluble in the acid pH's of the stomach, generally about 1.0 to 4.0, but relatively insoluble at the non-acidic pH's of the mouth. The coatings provide for rapid release and absorption of the drug, which is generally desirable in the case of liquid dosage forms.
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DENTIFRICE

(WO2001003662) 18.01.2001 A61K 8/27 VITA-MYR INTERNATIONAL CORP.
A non-alcoholic dentifrice for controlling gum disease and bad breath includes natural constituents such as nutrients which aid in cell reproduction, immunity, and wound healing and herbal supplements having anti-bacterial and anti-inflammatory properties. An optional embodiment of the solution includes approximately 10 % by mass folic acid, 10 % by mass zinc, 25 % by mass myrrh oil, 25 % by mass clove oil, and 30 % by mass water. A single dose of five milliliters includes approximately 0.5 milligrams folic acid, 0.5 milligrams zinc, 1.25 milligrams myrrh oil, 1.25 milligrams clove oil, and 1.5 milligrams water.
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SYNTHETIC RESIN TUBE CONTAINER

(WO2001002262) 11.01.2001 B65D 35/10 YOSHINO KOGYOSHO CO., LTD.
A synthetic resin tube container formed so as to shorten the length of a mouth-neck part and avoid double walls from being overlapped with each other in a structure for mounting a cap to the mouth-neck part in order to reduce the amount of molding material, wherein the upper surface of the mouth-neck part (4) erected from a shell part (2) of a container body (1) through an inward flange-shaped wall (3) is closed by a top wall (6) having a spout hole (5), and an insert tube (12) connected through a hinge (15) to a cover plate (13) of a cap main body is fitted closely to a close-fitting recessed groove (7) provided around the upper surface of the inward flange-shaped wall (3).
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ORAL COMPOSITION COMPRISING CAPSULES

(WO2001001938) 11.01.2001 A61K 7/16 UNILEVER N.V.
Oral composition comprising capsules, which capsules contain keratin characterised in that the keratin is substantially insoluble in water.
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PORCELAIN COMPOSITIONS FOR LOW EXPANSION ALL-PORCELAIN CORES AND ALLOYS

(WO2001001924) 11.01.2001 A61K 6/06 JENERIC/PENTRON INCORPORATED
A dental porcelain composition comprises an amorphous glass phase with a maturing temperature less than about 850 C, wherein the amorphous glass phase, in one embodiment, comprises (I).
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DENTAL MODEL BASE ASSEMBLY

(WO2001001881) 11.01.2001 A61C 9/00 HUFFMAN, Ronald, E.
A premanufactured dental model base, and method, for supporting a cast dental model. The dental model base may be selectively connected to an articulator attachment plate which is adaptable for connecting the dental model base to a metal articulator. The same dental model base, at a user's option, may also be connected to a disposable articulator through a groove in the base that engages a disposable articulator tongue or by connecting a disposable articulator ball directly to a socket in the base. Thus, the dental model base may be conveniently used with either a metal articulator or a disposable articulator. In one embodiment, a concave socket at one end of the dental model base may engage an articulator ball or may engage the articulator...
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FLAVORED CYANOACRYLATE COMPOSITIONS

(WO2001000742) 04.01.2001 A61L 24/06 CLOSURE MEDICAL CORPORATION
A sterile or non-sterile flavored monomeric adhesive composition includes a flavoring additive and a monomer. The composition can be applied, for example, to skin or the inside of the mouth. A method of making a sterile flavored adhesive composition includes placing a mixture of a polymerizable adhesive monomer and a flavoring additive in a container, sealing the container, and sterilizing the mixture and the container. The flavored adhesive composition is particularly useful as a medical adhesive and can include 1,1-disubstituted ethylene monomers, such as $g(a)-cyanoacrylates.
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DENTAL ANTI-HYPERSENSITIVITY COMPOSITION AND METHOD

(WO2000078270) 28.12.2000 A61K 6/00 THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
The present invention relates to compositions and methods for calcifying dental tissue, e.g. preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion.
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MEDICAL MEMBRANE FOR STIMULATING TISSUE FORMATION

(WO2000076418) 21.12.2000 A61C 5/00 IVOCLAR VIVADENT AG
The invention relates to a dental pulp membrane for covering the opened and/or partially reset pulp in a deep dentine wound resulting from a trauma or a restorative measure in a sterile, tight manner. According to the invention, the membrane is biocompatible at least on the side facing away from the pulp. The composition, structure and surface texture of the membrane make it suitable for cell addition, cell integration and tissue formation, optionally also stimulated by growth factors and/or bacteriostatic or bactericidal active agents. The membrane is also self-bonding or bonding on the tooth hard substance surrounding the pulp opening in such a way as to create a tight seal and is impermeable to solid and liquid materials or cells on the ...
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METHOD FOR OBTAINING A BUILDING MATERIAL

(WO2000075450) 14.12.2000 E04C 1/41 VIDAL MAURELL, Joan
Said material consists of plates obtained by molding and attached to one another, having an intermediate insulating layer. The inventive method involves the following steps: a) a first (2) and a second plate (1) are initially molded; b) a block made of insulating material (3) is placed on said first plate (2), the above-mentioned block having the same or similar dimensions as the plate, at least one hole defining a cavity (4) having been made in the plate and the first plate being the bottom of said cavity; c) the cavity (4) is filled with a material or fluid (5) that can be hardened and having adhesion or binding properties, the material or fluid spilling over the mouth of said cavity and d) the second plate (1) is superimposed on said ins...
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COMPOSITION AND METHOD FOR TREATING DENTAL CARIES USING INORGANIC METAL SALTS

(WO2000074639) 14.12.2000 A61K 7/16 UNIVERSITY OF SOUTHERN CALIFORNIA
In accordance with the present invention there is provided an oral composition comprising an effective amount of an orally acceptable carrier and an anti-caries agent that can reduce the activity of the enzyme glucosyltransferase. Also provided are methods of treating dental caries using such oral compositions and methods of manufacturing such oral compositions.
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ORAL COMPOSITION CONTAINING PERLITE

(WO2000074638) 14.12.2000 A61K 8/22 UNILEVER N.V.
An oral composition comprises perlite, characterised in that it comprises from 0.01 to 0.9% by weight perlite.
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IMMOBILIZED LACTOFERRIN (Im-LF) ANTIMICROBIAL AGENTS AND USES THEREOF

(WO2000072874) 07.12.2000 A23B 4/22 NAIDU, A., Satyanarayan
Disclosed is a composition of matter comprising a defined dispersion of isolated lactoferrin immobilized on a naturally occurring substrate via the N-terminus region of the lactoferrin; and at least one pharmaceutically acceptable carrier. The inventive pharmaceutically acceptable compositions, containing immobilized lactoferrin (Im-LF), are formulated in a wide variety of embodiments, including cosmetics, cleansers, food supplements, or medicaments, and for numerous useful delivery systems. Compositions comprising Im-LF are used in methods of preventing or inhibiting the growth and/or adhesion of a microbe in or on a vertebrate subject, and on a biological surface, such as a cellular, mucosal, epithelial, or eggshell surface, or in a biolo...
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ANTIGLARE OPTICAL DISPLAY SCREEN

(WO2000071373) 30.11.2000 B60J 3/02 DOMINGUEZ DIAZ, Jos Carlos
The invention relates to an antiglare optical display screen comprising a rectangular plate (1) having a rectangular notch (4) on the top length thereof, two fixing lugs (3) slightly projecting beyond the plane of said plate (1) being soldered on the width thereof and connected by a round rod (5) and a holding clip (6) that is fixed between the projecting lugs (3) by one of its faces. Said clip has ratchet wheels (8) cooperating with an internal pawl (9) provided in each lug (3). The ratchet wheels (8) have a central cubical opening with a diverging profiled mouth through which the rod (5) can be pressed until it is placed in said cubical mouth thereby serving as axis of rotation for the plate (1). The invention can be applied in automobile...
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PORTABLE TOOTHBRUSH

(WO2000070999) 30.11.2000 A46B 5/00 WOO, Leeki
This invention, toothbrush, is easy to carry and convenient and hygienic to use. This invented toothbrush has both tooth brush and tooth paste. The toothpaste tube has inlet and outlet to charge and discharge the toothpaste respectively. The protective cap of toothbrush can be used as a toothbrush holder when brushing teeth. This invention is composed of: a round toothpaste tube made of soft resin materials has outlet and inlet at top and bottom of the tube respectively, a toothbrush with a supplementary and an outlet caps, which are assembled to the toothpaste tube outlet, a transparent cap, which protects and covers the brush and is used as a toothbrush holder when brushing teeth by inserting it to the outside of the supplementary cap in ...
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PREVENTION OF DENTAL CARIES

(WO2000069890) 23.11.2000 A61K 38/08 STRMBERG, Nicklas
A penta- to decapeptide containing two or more Arg protecting against dental caries is comprised by the amino acid sequence GlyGlyHisProArgProProArgGlyArgProGlnGlyProProGlnGln. Also disclosed is a composition for preventing dental caries comprising an effective amount of the peptide, and a corresponding method of use.
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METHOD FOR THE MANUFACTURE OF TOOTHPASTE

(WO2000069401) 23.11.2000 A61K 8/19 COLGATE-PALMOLIVE COMPANY
A method is disclosed for the manufacture of a toothpaste containing an ingredient mixture of a calcium carbonate abrasive, a thickener and an aqueous humectant wherein there is sequentially added the calcium carbonate abrasive dispersed in a high solids aqueous dispersion containing 50 to 80% by weight calcium carbonate to the aqueous humectant and thereafter adding the binder and binding the ingredients before any further ingredients are added to the mixture to produce the toothpaste.
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A PORTABLE COOKING AND/OR HEATING APPARATUS

(WO2000069317) 23.11.2000 A47J 37/07 MCGURGAN, Martin
The present invention provides a portable cooking and/or heating apparatus (10) comprising an oven chamber (14) in which food may be roasted or baked. Mounted above the oven chamber is a fuel chamber (16), the fuel chamber (16) defining a mouth portion appositely disposed to the oven chamber and adapted for grilling food thereon. Disposed between the oven chamber and the fuel chamber is a convex apertured plate which permits air to flow between the oven chamber and the fuel chamber, thereby heating the oven chamber.
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CLEANING APPARATUS

(WO2000067923) 16.11.2000 A61C 19/00 POWELL-CULLINGFORD, Andrew, William
A cleaning apparatus preferably for dental tools comprises a pipe member (4) releasably attachable to a fluid flow means (3) such as the hose of a dental aspirator. A barrel member (20) is provided having means (6) for causing the barrel member to rotate in a fluid flow through the pipe member the barrel being provided with internal cleaning means (9) such as bristles arranged to contact a dental tool (2) placed within the barrel member. In use a fluid flow through the pipe member causes the barrel to rotate inside the pipe and a tool placed in the barrel is then cleaned by the rotation of the bristles around the tool.
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ORAL STEROIDAL HORMONE COMPOSITIONS AND METHODS OF USE

(WO2000067708) 16.11.2000 A61K 7/16 BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Provided are oral dentifrice compositions comprising a therapeutically effective amount of estrogen or an estrogen-containing substance. A variety of different methods of using the compositions, for example in the treatment or prevention of tooth loss or osteoporosis, are also provided. Additionally, therapeutic kits comprising one or more of the present compositions are provided.
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SELF-ADHESIVE POLYMERIZABLE MONOMER AND DENTAL/MEDICAL COMPOSITIONS THEREFROM

(WO2000067701) 16.11.2000 A61K 6/00 DENTSPLY INTERNATIONAL INC.
The synthesis of self-adhesive polymerizabe monomers and their application as a water containing and a water free self-adhesive dental/medical composite is described. The dental/medical composite comprises a self-adhesive polymerizable monomer, a polymerizable monomer, an acid-reactive and/or reactive and/or non-reactive filler, a diluent, a polymerization initiator and a stabilizer. As polymerization initiators are used the commonly known thermal initiators, redox initiators and/or photo initiators. The new adhesive dental composite develops adhesion to dentine of about 4 MPa. Fillers of high X-ray absorbance provide radio-opacity values graeter than that of the same thickness of aluminium.
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MECHANISM FOR ANIMATED CHARACTER

(WO2000066238) 09.11.2000 A63H 3/36 MERRIMENT INC.
A character (2) capable of forming facial expressions is provided. The character includes a hollow head (4) with a face defining a mouth (6) thereon. The mouth has a length and includes a first end portion (6A), a second end portion (6B), and a central portion (6C). The character further includes, externally or within the hollow head, a mechanism (7) for causing various facial expressions. The mechanism includes a main frame plate (8), a mouth assembly (10) fixedly mounted on the main frame plate, and a drive assembly (12) also mounted on the main frame plate. The mouth assembly includes an upper lip chain (14), which is formed from a plurality of links (16) and has a first end (14A), a second end (14B), and a center portion (14C). The uppe...
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UNIVERSAL DEVICE FOR PREVENTING RESPIRATORY FAILURE, FOR ADMINISTERING DRUGS PROGRESSIVELY AND FOR CURING SNORING

(WO2000066224) 09.11.2000 A61F 5/56 OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTJU 'NAUCHNO-PROIZVODSTVENNAYA FIRMA 'INKOMK'
The present invention pertains to medical techniques and can be used as a means for preventing and treating short respiratory failure, e.g. snoring, or as a means for progressively administering drugs in a dosed manner through the mouth during the sleep or awakening periods. The purpose of this invention is to increase the functional capacity of the device and to improve comfort during application, wherein said invention increases the range of potential applications of said device and improves its convenience of use. This invention essentially relates to a universal device for preventing and treating respiratory failure, for and administering drugs progressively through the mouth and for curing snoring. This device includes a connection pla...
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SUGAR ALCOHOL GRANULE AGGREGATE AND METHOD FOR PREPARING THE SAME

(WO2000066171) 09.11.2000 A23L 1/09 FREUND INDUSTRIAL CO., LTD.
A sugar alcohol granule for direct compression processing, a preparation method therefor, and a drug and a food comprising the same which can be rapidly disintegrated in a mouth. A granule aggregate containing sugar alcohol in an amount of 95 wt % or more, characterized in that 95 wt % or more of the aggregate is present as particles of 710 $g(m)m or less and 70 wt % or more of the aggregate as those of 75 to 710 $g(m)m, and the aggregate has a bulk density of 0.5 g/ml or more and an angle of repose of 40 or less. A sugar alcohol granule aggregate, and a method of preparing the granule aggregate comprising a step charging a sugar alcohol powder on a circular plate rotating in a treating chamber of a centrifugal rolling granulating apparat...
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UTILIZATION OF NANOSCALAR, ANTIMICROBIAL ACTIVE INGREDIENTS IN ORAL AND/OR DENTAL HYGIENE

(WO2000066070) 09.11.2000 A61K 8/04 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to the utilization of nanoscalar, antimicrobial active ingredients with an average particle size in the region of between 5 and 500 nm, for producing oral and/or dental hygiene products, in particular, for producing toothpastes or gels for cleaning the teeth. In contrast to active ingredient forms described in prior art, the especially fine distribution of the particles allows the active ingredients to be more easily integrated into formulations and to be more effective.
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INTERPROXIMAL TOOTH COATING APPLICATOR

(WO2000066025) 09.11.2000 A61C 3/06 NEKS RECHERCHE ET DEVELOPPEMENT INC.
The present invention relates to a tooth coating applicator (10), typically in the form of a strip (11), and a method for applying a dental sealant to a surface of a tooth (T), and specifically to the interproximal surface (S) thereof. The applicator (10) is elongated and is adapted to be typically inserted into an interproximal space (I) defined between a pair of adjacent teeth (T, T') and to be gradually slid against a dental surface of one of the teeth. The applicator (10) comprises a series of substrates (12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 36, 40, 42) for generally successively removing debris and deposits from the interproximal dental surface (S), etching (20) the dental surface (S), washing (22) the dental surface (S), drying (24...
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MEDICAMENT CARRIER

(WO2000064778) 02.11.2000 A61K 9/70 GLAXO GROUP LIMITED
There is provided a carrier comprising an elongate strip (10) having a first portion and a second portion; a fold between said first portion and said second portion such that the first portion contacts the second portion; and a join between the first portion and the second portion, wherein said join and the fold form the edges of a pocket or pouch (20) for containment of product. The carrier is suitable for the containment of a range of different products, particularly medicaments.
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METHOD FOR MAKING A BUSTER PACKAGE

(WO2000064747) 02.11.2000 B65B 11/50 GLAXO GROUP LIMITED
There is provided a method of forming a blister pack comprising contacting a base sheet having a blister pocket therein with a cover sheet and applying laser energy to form a join between said cover sheet and said blister pocket of said base sheet. The blister pack is preferably in the form of an elongate strip. The blister pack is suitable for the containment of a range of different products, particularly medicaments.
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DENTAL CASTING ALLOY

(WO2000064402) 02.11.2000 A61K 6/04 BIORTHEX INC.
A dental casting alloy based on Ni and Ti and having addition of cast of Mo, Fe, Cu and Co has the following composition in weight %:Ti: 40 - 50 % Mo: 0.2 - 2.0 % Fe: 0.1 - 1.5 % Cu: 0.1 - 1.0 % Co: 0.1 - 0.5 % Ni balance to a total of 100 %; the alloy has advantages over prior alloys for dental castings including a high level of fluidity, a low shrinkage percentage, a low melting temperature and super elasticity.
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WASHING DEVICE

(WO2000064324) 02.11.2000 A47L 13/19 UNILEVER PLC
An article (1) for scrubbing comprises a substantially flat flexible polymeric sheet having a first face (4) for scrubbing and a second face (5), which in use contacts a user's hand. The scrubbing face (4) includes a plurality of pockets (3), each pocket (3) having a mouth which is exposed on the scrubbing surface, each pocket (3) being dimensioned to receive a cleaning composition which during use is exposed through a mouth of at least some of said pockets and delivered onto a surface being treated. The invention also describes a process for cleaning hard surfaces using a scrubbing article according to the invention, and a kit comprising an abrasive composition and one or more scrubbing articles according to the invention.
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COMPOSITION CONTAINING OPIOID ANTAGONISTS AND SPRAY DISPENSER

(WO2000062757) 26.10.2000 A61K 9/00 BRITANNIA PHARMACEUTICALS LIMITED
A spray applicator is disclosed for administering an opioid antagonist selected from naloxone and/or naltrexone. The applicator is capable of delivering single or multiple doses of the antagonist through a projecting delivery portion which is shaped or dimensioned for introduction into the nose or mouth. A pharmaceutical composition for nasal or oral administration is also disclosed which comprises an opioid antagonist, such as naloxone and/or naltrexone, and which comprises a water-susceptible solid carrier admixed with the opioid antagonist.
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ORAL CARE COMPOSITIONS CONTAINING BOSWELLIA EXTRACTS

(WO2000062751) 26.10.2000 A61K 8/63 QUEST INTERNATIONAL B.V.
A composition suitable for use in the oral cavity comprises at least one extract of a Boswellia plant, or at least one boswellic acid or derivative thereof; and a carrier comprising at least one flavour ingredient. The extract, or boswellic acid or derivative thereof, is useful in preparing compositions or products with the ability to soothe irritation, or treat inflammation, in the oral cavity.
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ANTI-TARTAR DENTAL PRODUCT AND RELATED METHOD

(WO2000062749) 26.10.2000 A61K 8/19 UNILEVER N.V.
An oral product and method is provided for inhibiting tartar formation on the teeth. The product is housed in a container and includes a first composition containing a water soluble calcium phosphate salt or monolithic combination of calcium and phosphate salts in a carrier with the first composition having a pH less than 7, and a second composition containing an alkaline material and a fluoride ion source in a carrier to achieve a pH greater than 7.5. The first and second compositions are separated from one another prior to use. When combined upon application to the teeth, the first and second compositions form a system for inhibiting tartar around the teeth.
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METHOD AND APPARATUS FOR TREATING DENTAL CARIES

(WO2000062701) 26.10.2000 A61C 5/00 DENFOTEX LTD
A procedure for treating dental caries is described comprising the steps of gaining access to a carious lesion, contacting the lesion with a photosensitiser, activating the photosensitiser by exposing the lesion to light of a wavelength which is absorbed by the photosensitiser using an optical fibre permitting illumination of the area of the lesion to kill bacteria in the region of the lesion, and infusing the treated dentine with a polymerisable sealing or filling composition and causing said composition to cure.
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APPARATUS AND METHOD FOR THE PROCESSING OF SOLID MATERIALS, INCLUDING HARD TISSUES

(WO2000062694) 26.10.2000 A61C 1/00 ALTSHULER, Gregory
A method, and apparatus are provided for processing solid material in general, and dental material (12) in particular, which involves applying radiation from a pulsed laser (7) to ablate the material (12). Particles of ablation (13, 14) are generated by the radiation (1) form the area of processing, and/or other sources which are reflected by reflector (10) to the area of processing to further ablate the material (12). Ablation particles (13, 14) may also be obtained form the ablation of the tip (9), form a strip of material (25) through which radiation passes before reaching the region of processing or from other sources. A mechanism (17, 18) may also be provided for cooling the surface of the material in the region of processing between r...
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XANTHAN VISCOSIFIED COMPOSITIONS AND PREPARATION THEREOF

(WO2000061674) 19.10.2000 C08B 37/00 CP KELCO U.S. INC.
A xanthan gum viscosifier having enhanced hydration and dispersibility properties and xanthan viscosified compositions demonstrating improved thermal stability with retained low shear rate viscosity, is disclosed. Also disclosed is a process for improving the thermal stability and low shear rate viscosity of viscosified compositions and a process for the preparation of divalent cation-containing xanthan viscosified compositions using low shear mixing.
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IMPROVED POLYVINYLSILOXANE IMPRESSION MATERIAL

(WO2000061075) 19.10.2000 A61K 6/10 DENTSPLY INTERNATIONAL INC.
Improved two component polymerizable polyorganosiloxane compositions are described, particularly for use in making dental impressions, having improved tear strength and wettability. Improved tear strength results from inclusion of a quadri-functional polysiloxane having a vinyl content of 0.16 to 0.24 m-mole/g. Working time is maintained by including sufficient amounts of a retarder composition that delays onset of the vinyl polymerization. Wettability is improved by including a surfactant resulting in a surface contact angle with water at three minutes of less than 50. The surfactant chosen has an HLB of 8-11, such that the wetting contact angle is achieved within less than two minutes and remains wetting throughout the working time of t...
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METHOD AND DEVICE FOR CLEANING, DISINFECTING OR LUBRICATING MEDICAL, ESPECIALLY DENTAL HANDPIECES OR THE LIKE

(WO2000061032) 19.10.2000 A61C 1/18 PREGENZER, Bruno
According to the invention, a liquid agent (9) is dispensed from a container (1) and is introduced under pressure into the handpiece for the purpose of cleaning, disinfecting or lubricating said handpiece. For the purpose of dispensing the agent (9) the container (1) is revolved in such a manner that the outlet (12) is below the level (13) of the agent (9). The container (1) is then revolved so that the opening (12) is above the level (13) of the agent (9). The undesired residues of the agent (9) are then removed by blowing out the air (14) that is contained in the container (1).
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APPARATUS SUITABLE FOR RECORDING IN THE MOUTH AND FOR REPRODUCING IN THE LABORATORY THE POSITION OF THE DENTAL ARCHES IN RELATION TO THE CONDYLAR AXIS, SPECIFIC FOR APPLICATIONS IN THE FIELD OF DENTISTRY AND DENTAL TECHNIQUE

(WO2000059401) 12.10.2000 A61C 19/045 BATTISTUTTA, Lorenzo
An apparatus for recording in the mouth and the reproduction in the laboratory of the position of the dental arches in relation to the condylar axis, specific for the applications in the field of dentistry and dental technique. It includes a metal plate (1), a graduated rod (3) for the support of the plate (1), an occlusal plane (5) provided with goniometers (10), an articulator (29), a graduated rod (18) that supports the metal plate (1)-rod (3)-assembly on the base (11). The apparatus allows for the registration in the mouth and the reproduction in the laboratory of the values of the numerical coordinates that indicate the position of the plate (1) to the condylar axis of the patient.
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ORGANOPHOSPHORUS COMPOUNDS FOR DENTAL POLYMERIZABLE COMPOSITIONS

(WO2000058316) 05.10.2000 C07F 9/09 KURARAY CO., LTD.
An organic phosphate compound having at least one radically polymerizable double bond, at least one phosphate residue having one or two hydroxyl groups, and at least one hydrocarbon group having 4 or more carbon atoms in a molecule, wherein a 10 % by weight methanol solution of the organic phosphate compound has an electric conductivity at 25 C of 0.5 mS/cm or less, and/or the organic phosphate compound has a light transmittance at 455 nm of 90 % or more; a process for preparing the organic phosphate compound; a dental polymerizable composition comprising (a) the organic phosphate compound and (b) a polymerizable monomer capable of copolymerizing with the organic phosphate compound.
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ORAL ANTI-ODOR COMPOSITIONS

(WO2000057699) 05.10.2000 A01N 31/02 INNOSCENT LTD.
The invention is directed to a composition comprising a higher alcohol selected from 1-nonanol, 1-decanol and 1-undecanol, or mixtures thereof and taste-masking additives, or a lactone selected from gamma-methyl decalactone, gamma-decalactone, gamma-undecalactone and gamma-dodecalactone or mixtures thereof for use as an oral anti-odor preparation. The invention further provides anti-odor toothpaste, mouthwash, mouth drops, candies and other anti-odor preparations for oral use.
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ANTI-CARIES ORAL CARE COMPOSITIONS

(WO2000056276) 28.09.2000 A61K 7/16 THE PROCTER &GAMBLE COMPANY
The present invention relates to oral care compositions, including tooth pastes (including gels and gels for subgingival application), mouth rinses, mouth sprays, chewing gums, and lozenges as more fully described hereinafter. These compositions comprise: (a) a safe and effective amount of a non-cariogenic carbohydrate; and (b) a polyalcohol; wherein said polyalcohol is used in a level sufficient to promote greater uptake of said non-cariogenic carbohydrate by plaque, thereby resulting in creating an environment that does not favor development of caries. This invention further relates to a method for preventing and treating conditions in the mouth that favor formation of caries by the use of compositions as disclosed above.
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JOINT MATERIAL AND EXECUTION METHOD THEREOF

(WO2000055443) 21.09.2000 E04B 1/68 SEIKI KOGYO CO., LTD.
A joint material which can easily be set in a joint groove disposed between adjacent wall surface external facing materials of a building and requiring a watertightness. A joint base material (6) is provided continuously from and integrally with the surface of a synthetic resin joint joiner (4) disposed between wall surface external facing materials (A). The joint base material (6) has right and left side plates (12) between which a sealing material (8) is filled, two soft seal lugs (14a, 14b) projecting from the outer surface of each of the side plates with the free ends thereof contacting the end face of a wall surface external facing material, and a large number of holes (16) made between the seal lugs. A core material (10) to be pressed...
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STERILANT COMPOSITION

(WO2000054594) 21.09.2000 A01N 59/12 SALTER, Roy
A sterilant composition consists essentially of an aqueous solution of from 0.2 % to 1.0 % w/v of potassium iodide (KI) and an amount of iodine (I2?) in % w/v excess of the % w/v amount of the potassium iodide up to the maximum solubility of iodine in the potassium iodide solution. Preferably the ratio by weight of potassium iodide to iodine is 1:1.5. The composition is useful for cold sterilisation of surgical and dental instruments.
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A DISPOSABLE TOOTHBRUSH

(WO2000053053) 14.09.2000 A46B 11/00 TRI-CONCEPTS (PROPRIETARY) LIMITED
This invention relates to a compact disposable toothbrush in combination with a toothpaste dispenser for use by travellers and persons suffering from oral diseases. The toothbrush comprises a toothbrush head (12) which included a base (22), bristles (24) and a cap (36). The cap (36) contains toothpaste behind a sealed membrane (42), or within a sachet (not shown). In use, the cap is pressed laterally relative to the head (22), pointed ridges (32) perforate the membrane (42) and the toothpaste is caused to flow through an aperture (34) in the base (22) to the bristles (24). The handle (14) of the toothbrush includes a first cavity (16) containing a supply of dental floss and a second cavity (18) containing a supply of mouthwash. According to...
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DEVICE FOR THE CLEANING OF A LIQUOR SPRAY NOZZLE ASSEMBLY OF A SODA RECOVERY BOILER

(WO2000052259) 08.09.2000 D21C 11/12 SDERSTRM, Per
The invention relates to a device for the cleaning of a liquor spray nozzle assembly of a soda recovery boiler of the type that includes a liquor supply conduit (3) inserted through an opening (10) in a wall (11) of the soda recovery boiler, which conduit has a mouth (6) from which a plate (8) for distribution of liquor protrudes, more precisely from a lower part of the mouth. The device comprises a scraper means (2) which is movable reciprocally along side edges on the distributing plate (8) by means of a power generator (12) mounted in a supporting stand (13). The scraper means (2) comprises a U-shaped clamp (25) with a bottom piece (26) located under the distributing plate (8) as well as two side pieces (27), which are mutually spaced-ap...
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ORAL DRUG DELIVERY SYSTEM

(WO2000051593) 08.09.2000 A61K 9/00 WEST PHARMACEUTICAL SERVICES DRUG DELIVERY &CLINICAL RESEARCH CENTRE LIMITED
An oral drug delivery composition that dissolves rapidly in the mouth, which comprises on a solid foam formed from a protein.
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SMOKING UTENSIL

(WO2000051452) 08.09.2000 A24F 13/14 YANO, Akira
A smoking utensil capable of adequately preventing the flowing-out of cigarette sub-flow smoke, being free from inner deposition of nicotine and tar without such trouble as cleaning and ensuring constant flow of as much air as is required by cigarette burning, comprising a smoking utensil main body (1) obtained by forming diatomite into a bottomed cylinder with pores left open to permit as much air as is necessary for cigarette burning to flow theretrhrough but to prevent the flowing-out of sub-flow smoke and a storing room (2) formed inside the main body (1) and into which the tip end of a cigarette can be inserted air-tightly, wherein a cigarette (C) is lighted with its filter tip fitted in a mini-pipe (P) and inserted into the storing ro...
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AN AQUEOUS NON-ALCOHOLIC ORAL RINSE CONTAINING BENZOCAINE AND CARBOMER

(WO2000049994) 31.08.2000 A61K 8/44 DEN-MAT CORPORATION
A transparent, alcohol-free, aqueous oral rinse composition comprising more than 0.04 % by weight benzocaine, carbomer in an amount that is roughly equal to half the amount of benzocaine employed, and water. The composition relieves the soreness of aphthous ulcers and similar mouth sores.
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MILK PROTEIN HYDROLYSATE FOR ADDRESSING A BONE OR DENTAL DISORDER

(WO2000049885) 31.08.2000 A23J 3/10 SOCIETE DES PRODUITS NESTLE S.A.
A composition for prevention or treatment of a bone or dental disorder which comprises a milk protein hydrolysate, use of the milk protein hydrolysate in the manufacture of a composition for the treatment or prevention of a bone or dental disorder, and a method of treatment which comprises administering an effective amount of a milk protein hydrolysate. In preferred embodiments the milk protein hydrolysate is a hydrolysate of casein, in particular a caseinoglycomacropeptide (CGMP), a mimetic, homologue or fragment thereof in a bioavailable form which retains the ability of CGMP to inhibit bone resorption or bone loss; or favor calcium absorption, retention or calcification; or a combination thereof.
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EPOXY COMPOUNDS FOR DENTAL MEDICAL AND/OR DENTAL TECHNICAL APPLICATIONS

(WO2000049064) 24.08.2000 A61K 6/087 LSP DENTAL CHEMISTRY AG
A composition for dental medical and/or dental technical applications, whereby said composition can be polymerized by means of cationic polymerization with the aid of visible light. The inventive composition comprises one or several epoxy compounds, a plasticizer, a catalyst for ring scission hardening, a catalyst for daylight hardening and an accelerator consisting of a non-alkaline tertiary amine.When the composition is exposed to light at a wavelength of 340-500 nm, it hardens without almost any shrinkage and sticking.
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ACID RESISTANT FILM FORMING DENTAL COMPOSITION AND METHOD OF USE

(WO2000048562) 24.08.2000 A61K 6/00 COX, Charles, F.
A method of utilizing a solution of oxalic acid potassium salt, dihydrate 99 % to react with calcium in the dentinal fluid forming an insoluble white precipitate of calcium oxalate which occludes the dentinal tubules causing decreased sensitivity, permeability and acid penetration of the dentin. A liquid composition of oxalic acid potassium salt, dihydrate 99 % containing about 1.5 % to about 10 % by weight oxalic acid potassium salt, dihydrate 99 % having a particle size of about 1 to about 10 microns when view by a 100 power microscope. The liquid composition has a pH of about 2.0 to 4.0. Methods of preparing the liquid composition are disclosed.
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HYDROPHILICALLY MODIFIED CURABLE SILICONE IMPRESSION MATERIAL

(WO2000048553) 24.08.2000 A61K 6/10 KERR CORPORATION
The present invention provides hydrophilically modified curable silicone dental impression materials comprising an addition curable silicone prepolymer composition and a polymerizable hydrophilic modifier. The addition curable silicone prepolymer in the composition of the present invention comprises blended vinyl terminated organopolysiloxane fluids, an organohydrogen polysiloxane crosslinker, a platinum catalyst, a retarder, filler and optional additives. The cured compositions have a stable hydrophilic nature, excellent mechanical properties, and maximum long-term dimensional stability.
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ORAL HYGIENE DEVICE, ESPECIALLY A TOOTHBRUSH

(WO2000048484) 24.08.2000 A46B 5/00 REUSS PATENTE AG
The invention relates to an oral hygiene device, especially a toothbrush. The device consists of a handle (1) and a cleaning head (10) which is provided at the end of said handle and which supports an essentially flexible material (2) used for oral and dental hygiene. This material (2) is especially detachably fixed to the cleaning head.
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COMPOSITION FOR TREATMENT OF EXTERNAL SECRETION DISORDERS EXCEPT HYPOLACRIMATION

(WO2000048447) 24.08.2000 A61K 31/00 R-TECH UENO, LTD.
A composition for treatment of external secretion disorders except hypolacrimation which comprises, as an active ingredient, an aldose reductase inhibitor. The composition is effective in at least one of diseases selected from hyposalivation and dry mouth syndrome. More specifically, the aldose reductase inhibitor is a compound represented by general formula (I), wherein A and B are independently lower alkylene, X, Y, and Z are independently halogen, or a pharmacologically acceptable salt thereof.
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DERIVATIZED MICROFIBRILLAR POLYSACCHARIDE

(WO2000047628) 17.08.2000 A61K 8/73 HERCULES INCORPORATED
A method for producing derivatized microfibrillar polysaccharide, including but not limited to cellulose, derivatized by steric and/or electrostatic forces, where the electrostatic forces are provided by anionic charge or by a combination of both anionic and cationic charge, by stabilizing and/or microfibrillating a polysaccharide starting material. A method of modifying the rheological properties of a composition of matter using derivatized microfibrillar polysaccharide. Method of improving coatings, paper manufacture, and the stability of emulsions, dispersions, and foams using a derivatized microfibrillar polysaccharide. Compositions that include derivatized microfibrillar polysaccharide, including paper compositions, comestible composit...
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REMINERALIZING/MINERALIZING ORAL PRODUCTS HAVING IMPROVED WHITENING AND STAIN REMOVAL PROPERTIES

(WO2000047173) 17.08.2000 A61K 8/24 ENAMELON, INC.
An oral product, preferably a toothpaste, effective for remineralizing subsurface dental lesions, mineralizing exposed dentinal tubules and whitening teeth stained with discoloring residues containing heavy metal ions such as Fe?+3, Mn?+2 and Cu?+2, is composed of a first discrete part composed of a water-soluble or partially water-soluble calcium salt and optionally a non-toxic, non-calcium water-soluble divalent metal salt, and a second discrete part composed of a water-soluble orthophosphate salt and preferably a water-soluble fluoride salt. Further enhanced stain-removing properties without excessive abrasivity are imparted to the oral product when part (A) further contains an effective amount of an anhydrous dicalcium phosphate a...
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ANTI-PLAQUE EMULSIONS AND PRODUCTS CONTAINING SAME

(WO2000045789) 10.08.2000 A61K 8/06 WM. WRIGLEY JR. COMPANY
Anti-plaque emulsions and methods of use are provided. The emulsion comprises a surfactant, emulsifier, and triclosan.
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METHOD AND APPARATUS FOR DENTAL TREATMENT USING HIGH PRESSURE LIQUID JET

(WO2000045731) 10.08.2000 A61C 1/00 SURGIJET, INC.
The invention is a method, and apparatus for dental procedures using a dental hydro-jet tool (35) having a cannula (34) extending therefrom. The cannula (34) is connected to a source of high pressure liquid, and delivers a high velocity, high pressure jet. For root canal procedures, the cannula (34) is directed through an opening (32) in the crown (11) of the tooth (10), the hydro-jet (35) is directed at the pulp, nerve, and vascular tissue within the interior chamber (26). The jet (36) may comprise medical grade saline, disinfectant, antibiotic or abrasive solutions. All the soft tissue within the tooth (10) is cut, excised, emulsified, and aspirated out of the tooth (10). The time required to excise, emulsify, and aspirate all the soft ti...
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A PHARMACEUTICAL COMPOSITION OF COMPLEX CARBOHYDRATES AND ESSENTIAL OILS AND METHODS OF USING THE SAME

(WO2000044367) 03.08.2000 A61K 31/715 DERMAL RESEARCH LABORATORIES, INC.
The invention discloses the discovery that a pharmaceutical composition containing complex carbohydrates with or without natural or synthetic essential oils can work effectively as a topical, oral or mucosal pharmaceutical composition. Such pharmaceutical compositions reduce inflammation, assist in wound healing, protect against bruising, relieve itching, relieve pain and swelling and treat topical bacterial infections such as acne and decubitus ulcers and prevent and treat numerous other conditions and diseases. Such pharmaceutical compositions can be administered to mammals including humans. Also included in this invention are methods to deliver topically applied macromolecules into the tissue of mammals and methods of blocking the adhesi...
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ORAL HYGIENE PREPARATIONS; ASSOCIATED METHODS AND KIT

(WO2000044338) 03.08.2000 A61K 7/16 BIOGLOBE TECH, INC.
Oral hygiene preparations, an associated method, and kit for utilizing same is disclosed and wherein the oral hygiene preparations reduce the incidence of caries in patients, including immunocomprimised and chemotherapy treated patients. The method includes contacting the patient's teeth and surrounding oral cavity with a toothpaste and mouthwash composition comprising a therapeutically effective amount of Cetyl Pyridinium Chloride and Dehydroacetic Acid; and exposing the patient's dental appliances and toothbrush periodically to a disinfecting solution comprising a therapeutically effective amount of Cetyl Pyridinium Chloride and Dehydroacetic Acid.
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MOTOR-DRIVEN APPARATUS FOR THE MECHANICAL CLEANING OF THE INTERDENTAL SPACES BY DENTAL FLOSS

(WO2000044302) 03.08.2000 A61C 15/04 SANTORO, Giovanni
An apparatus for the mechanical cleaning of the interdental spaces by dental floss comprising an outer holder containing a delivery reel of the fresh dental floss and a take-up reel of the worn-out dental floss, means for reciprocating the operating length of the dental floss between the arms of a fork to be positioned within the mouth in the interdental spaces, and means provided with friction device for rotating the delivery and take-up reels as well as the driving wheels transmitting the movement of the drive means to the delivery and take-up reels, an outside case including the drive means for the above-mentioned reciprocation and the power supply battery, a support base for two holders and a drive case carrying induction means for rech...
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EGR COOLER

(WO2000043663) 27.07.2000 F02M 25/07 HINO MOTORS, LTD.
A shell and tube type water-cooled EGR cooler capable of increasing an efficiency of heat exchange between exhaust gas and cooling water, wherein a plurality of spiral projection lines are formed on the inner peripheral surfaces of tubes passing through plates and spiral wire material is closely fitted into the tubes, a bonnet located on an exhaust gas inlet side is formed in a bell mouth shape of which the bore increases gradually toward the flow direction of the exhaust gas; a flat box-shaped shell and tube type water-cooled EGR cooler, wherein a bonnet (6A) on an exhaust gas inlet side is formed in a bell mouth shape, and a truncated-chevron guide plate (21) is disposed in the bonnet and a round bar (22) is disposed at the intermediate p...
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DUAL COMPONENT DENTINAL DESENSITIZING DENTIFRICE

(WO2000042981) 27.07.2000 A61K 7/16 COLGATE-PALMOLIVE COMPANY
A two component dental composition is disclosed which eliminates or substantially reduces the discomfort and pain associated with dentinal hypersensitivity which composition comprises a first dentifrice component having an alkaline pH, a second dentifrice component having an acid pH and at least one of the components containing a potassium ion releasable compound, the first and second components being maintained separate from each other until dispensed and combined for application to teeth requiring relief from dentine hypersensitivity, whereby heightened desensitization is experienced by the user.
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CYCLOSILOXANE-BASED CROSS-LINKABLE MONOMERS, PRODUCTION THEREOF AND USE THEREOF IN POLYMERISABLE MATERIALS

(WO2000042092) 20.07.2000 C07F 7/21 3M ESPE AG
The invention relates to cyclic sol-gel-condensable siloxanes of general formula (1), wherein R?1, R?2 mean alkyl with 1 to 10, preferably 1 to 5 C-atoms, alkenyl with 1 to 10, preferably 1 to 5 C-atoms, fluoroalkyl 1 to 10, preferably 1 to 5 C-atoms, cycloalkyl with 3 to 12, preferably 5 to 12 C-atoms, aryl with 6 to 18, preferably 6 to 12 C-atoms; R?3 means H, R?5-Z, R?4 means R?6-(A-R?6)c?-SiXa?R?7b?; R?5, R?6 mean alkylene, linear or branched, with 1 to 10, preferably 2 to 6 C-atoms, alkenylene linear or branched, with 1 to 10, preferably 2 to 6 C-atoms, cycloalkene with 3 to 12, preferably 5 to 8 C-atoms, cycloalkenylene with 3 to 12, preferably 5 to 8 C-atoms, alkarylene with 6 to 18, preferably 6 to 12 C-ato...
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TRUNCATED OPEN INTERVERTEBRAL SPACERS

(WO2000041654) 20.07.2000 A61F 2/00 SDGI HOLDINGS, INC.
Open chambered spacers, implanting tools and methods are provided. The spacers (100) include a body (105) having a wall (106) which defines a chamber (130) and an opening (131) in communication with the chamber (130). In one embodiment the wall (106) includes a pair of arms (120, 121) facing one another and forming a mouth (110) to the chamber (130). Each of the arms has an end configured to form a region within which an adjacent spacer can nest. In one aspect the body (105) is a bone dowel comprising an off-center plug from the diaphysis of a long bone. The tool (300) includes spacer engaging means for engaging a spacer and occlusion means for blocking an opening defined in the spacer. In some embodiments, the occlusion means (320) include...
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BRUSH UNIT AND TOOTHBRUSH WITH BRUSH UNIT

(WO2000041592) 20.07.2000 A46B 9/04 BRAUN GMBH
The invention relates to a brush unit which is designed for use with a toothbrush provided with an electric drive serving to oscillate the brush unit in relation to an axis of movement (43). The brush unit comprises a brush support (41) and a plurality of bristles which are anchored in the support, protrude outwards from same and a grouped in bundles (44, 45). The brush unit in particular has bristles or bristle bundles (45) which are situated at a distance from the axis of movement (43) and inclined in relation to the axis of movement at an angle of inclination of, for example, approximately 6. The brush unit is particularly suitable for cleaning interdental spaces and removing dental plaque. It can be used especially advantageously with...
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A METHOD AND AN APPARATUS FOR FEEDING IMAGE PLATES USED FOR INTRAORAL DENTAL X-RAY PHOTOGRAPHY INTO A READING DEVICE

(WO2000041035) 13.07.2000 A61B 6/14 ORION-YHTYM OYJ
The invention relates to a method and an apparatus for feeding image plates (1) used in intraoral dental X-ray photography into a reading device. During the reading step an excited phosphorus layer on the plate (1) is scanned with a laser beam and is converted into a visible image on a display screen or a film. In accordance with the invention, the excited image plates (1) are removed from their protective bags and are stacked into a housing (2) which acts as their intermediate storage and is protected from light, from where the plates are gripped by a conveyor, such as a toothed belt (16), to be fed forwards. The plates can be pulled or pressed e.g. by a magnet (12) and/or a pushing device (15) towards a conveyor conducted laterally of the...
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METHOD FOR PRODUCING A RESEALABLE POUCH

(WO2000040465) 13.07.2000 B31B 19/90 IMPERIAL TOBACCO LIMITED
A method of producing resealable filled pouches comprises the steps of (i) folding across part of its original width a length of thermoplastics sheet to produce a folded sheet having a fold portion running lengthways of the sheet having a folded edge which fold portion extends across part of the original width of the sheet and a non fold portion extending from the fold portion to the other edge of the sheet; (ii) in a direction at right angles to the folded edge and at regular intervals along the folded edge, welding the fold portion together to form individual pockets of equal size having welded wall edges along the length of the sheet; (iii) cutting the sheet, across the width of the sheet and along the line of the welds, to produce indiv...
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DIETETIC CHOCOLATE COMPOSITION

(WO2000040101) 13.07.2000 A23G 1/00 DANISCO CULTOR AMERICA, INC.
A dietetic chocolate composition sweetened by a bulk sweetener system and a process for making the dietetic composition. The chocolate compositions are sweetened by a bulk sweetening composition which includes 10-90 % by weight of maltitol, 9-89 % by weight of lactitol and 1-30 % by weight of polydextrose. This combination of sweeteners provides a dietetic chocolate product with a surprisingly high degree of sweetness, a significantly reduced glycemic index and reduced caloric content and a taste profile, texture and mouth feel which closely approximates conventional chocolate products. The process of the invention incorporates this bulk sweetening composition into a chocolate product.
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CONTROLLED AND REGULATED CONVEYING OF FLUID MEDIUMS BY ELECTROCHEMICAL GAS GENERATION

(WO2000037130) 29.06.2000 A61M 5/14 WINSEL, August
An apparatus for conveying successively two fluid mediums, especially two drugs, to a human or to an animal client comprising a cylinder (12) with a first piston (9) near to the mouth (1) and a second piston (10) near to the end-plate (13), thus defining three partitions within the cylinder: partition one is situated between mouth (1) and piston (9) and contains the first medium; partition two is situated between piston (9) and piston (10) and contains the second medium; partition three is situated between piston (10) and endplate (13) and takes up the driving gas that is generated by an electrolytic process from gas cells. Piston (9) contains a by-pass (51) and a valve (52) within by-pass (51) for the flow of the second medium through pist...
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FINE SUSPENSIONS OF POORLY SOLUBLE CALCIUM SALTS AND THEIR USE IN DENTAL CARE PRODUCTS

(WO2000037033) 29.06.2000 A61K 8/04 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention relates to suspensions of poorly water-soluble calcium salts, selected from the phosphates, fluorides and fluorophosphates, in liquid media, preferably in water, containing suspended primary particles between 5 and 50 nm in diameter and between 10 and 150 nm in length. Said suspensions are stabilized by a contents of at least 0.01 % by weight, in relation to the weight of the suspension, of a water-soluble surface-active agent or water-soluble polymeric protective colloid so as to prevent agglomeration. The suspensions are suitable as remineralizing components in compositions used for the cleaning and care of the teeth.
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DENTAL FLOSSER AND DISPENSER

(WO2000036993) 29.06.2000 A61C 15/04 NOVOPICK INC.
Our invention relates to a 'Dental Flosser and Dispenser'. A particular application is for the device to be able to effectively floss and clean one's teeth free of food debris, plaque, tartar, and other such material imbedded in-between one's teeth, in particular after having a meal. The device's main focus is to replace the awkward use of tying and twining of the dental floss thread into one's fingers and hands (left) into the other one's fingers and hands (right) to floss one's teeth. The invention is designed not only to eliminate the use of ones hand in flossing but also to dispense the dental floss thread in a highly, effective, calibrated manner. The device, with its unique design, is able to both hold and dispense the dental floss th...
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ALL-SIDED MOUTHBRUSH

(WO2000035314) 22.06.2000 A46B 9/04 NOE, Dennis
An all-sided mouthbrush (10) for cleaning a mouth of a user. The all-sided mouthbrush (10) includes a handle (12) having at a second end (16) first (18) and second (22) sides, bristles (20) extending from the first side (18), and an alternate cleaning device (24) connected to the second side (22), wherein the bristles clean teeth of the user and the alternate cleaning device cleans a tongue and inner side of the mouth of the user. The alternate cleaning device may be in the form of one of a plurality of parallel ridges (26), a plurality of columns of tuft-shaped bristles (32), a plurality of spade headed bristles (36), a scouring pad-like surface (72) or a plurality of off set rows of bristle-like structures made of soluble crystals (80) fo...
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ORAL CARE COMPOSITIONS COMPRISING COENZYME Q10?

(WO2000033802) 15.06.2000 A61K 7/16 Q-PHARMA, INC.
The present invention provides oral care compositions comprising high concentrations of Coenzyme Q10? which are uniform, stable, and retain characteristics favorable to the consumer. The oral care compositions of the present invention include toothpastes and tooth gels, pastes, irragants, ointments, films, dental gels, mouth rinse, mouth spray, chewing gum, lozenges and a base composition for coating toothpicks and dental floss. In formulating the oral care compositions of the present invention, the Coenzyme Q10? is solubilized in a non-toxic solubilizing agent which is compatible with use in the oral cavity. The formulations further comprise a water soluble flavoring agent. Methods are also provided for preparing the oral care composit...
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DENTAL COMPOSITION

(WO2000033793) 15.06.2000 A61K 6/00 DENTSPLY INTERNATIONAL INC.
A dental composition including a mono- and/or a poly-cyanoacrylate, a polymerizable monomer, a stabilizer, an initiator, and optionally, pigments and a filling material.
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SQUEEZER FOR DENTAL PASTE

(WO2000032488) 08.06.2000 B65D 35/34 CAMPOS MARQUES, Arturo
The present invention relates to a squeezer for dental paste which is fixed to the wall and is comprised of a support shape like a three sided box and a tongue acting as a spring to exert pressure to a grooved key which is introduced transversally in the support; the sealed extremity of the dental paste tube is fixed to the grooved key. By turning the grooved key, the tube is rolled up when passing in between the grooved key and the tongue thereby impulsing the dental paste out of the tube, the portion of dental paste being dosed in proportion to the rotation of the key.
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COMPOSITIONS AND METHODS FOR WHITENING TEETH

(WO2000032133) 08.06.2000 A61C 13/08 TARVER, Jeanna, Gail
This invention is composition, methods, and systems for whitening teeth. A whitening composition is applied to off-white or yellowish teeth in order to hide or mask the inherent underlying natural tooth color to yield whiter looking teeth. The whitening composition includes a complementary dye that, when absorbed by a tooth, will cause the tooth to reflect a color of light that is whiter than the natural or initial color reflected by the tooth. The tooth whitening composition may comprise a toothpaste that is applied like any conventional toothpaste in order to achieve whitening without significant alteration of a person's daily routine. Alternatively, the tooth whitening composition may be adapted for direct application onto the teeth in a...
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SELF ETCHING ADHESIVE PRIMER COMPOSITION AND POLYMERIZABLE SURFACTANTS

(WO2000030591) 02.06.2000 A61K 6/00 DENTSPLY INTERNATIONAL INC.
The invention provides a self etching adhesive dental primer composition, a method of use of the primer composition and a product formed from the primer. The dental product is formed from the primer composition which includes water, surfactant and polymerizable material in suspension in the water. The polymerizable material includes monomers which are water immiscible. Preferably the monomers have an average molecular weight less than 1000. The primer composition is used by applying the composition to unetched dental tooth enamel and the polymerizable material is polymerized to form a dental product having adhesion to the enamel of more than 13 MPa. Improved surfactants which contain at least one ethenically unsaturated polymerizable group ...
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DISPOSABLE DENTAL INNER AND OUTER PICK

(WO2000030559) 02.06.2000 A61C 15/02 NOVOPICK INC.
Our invention relates to a 'DISPOSABLE DENTAL INNER PICK.' A particular application is for the device to be able to effectively clean the inside and outside teeth (in-between) and gumlines from food debris, plaque, tartar and other such foreign material imbedded in-between one's teeth in particular after having a meal. While the device's main focus is to clean in-between one's teeth inside and outside, it is also highly effective in massaging and stimulating gum tissue which prevents GINGIVITIS (a minor inflammation of the gum caused by plaque building up above one's gumline) when used in a conscientiously applied program of oral and dental care. Because of the nature of its intended use and purpose, for personal use in one's oral hygiene a...
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ANTIMICROBIAL CHEWING GUM

(WO2000030467) 02.06.2000 A23G 4/00 AGION TECHNOLOGIES, L.L.C. Attn: Edward K. Welch II
The present invention provides a novel chewing gum product generally for the lysis and killing of oral microbes. In a preferred embodiment, the chewing gum product comprises an antimicrobial metal ion component and an inorganic ceramic carrier, and provides a concentration of such substances from about 0.05 to 50 weight percent of the chewing gum. In particular, these compositions may comprise zeolites ion-exchanged with antimicrobial metals, in addition to other oral care compounds. The present invention also relates to methods of using such compositions for treating and inhibiting dental caries, dental plaque and gingivitis, oral malodor and periodontal conditions. The compositions of the present invention may be incorporated into chewing...
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PHOTOCURABLE COMPOSITION

(WO2000029453) 25.05.2000 C08F 2/48 TAIYO INK MANUFACTURING CO., LTD.
A photocurable composition which cures upon irradiation with not only ultraviolet but visible light, which comprises (A) an ethylenic compound, (B) a free-radical polymerization initiator, and (C) a tertiary thiophosphite. The initiator (B) is (B-1) a free-radical photopolymerization initiator having absorption wavelengths not shorter than 400 nm, (B-2) a free-radical photopolymerization initiator having absorption wavelengths shorter than 400 nm, or a mixture of the initiators (B-1) and (B-2). The composition is usable in a wide range of applications such as adhesives, coating materials, paints, molding materials, dental materials, and image-forming materials.
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DENTAL WHITENING COMPOSITION

(WO2000028955) 25.05.2000 A61K 6/00 MINNESOTA MINING AND MANUFACTURING COMPANY
Dental whitening compositions are provided that have the capability of undergoing an increase in viscosity in response to an increase in temperature. In a preferred embodiment, the composition also have the ability to reverse their viscosity in response to a decrease in temperature.
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COMPOSITIONS AND METHODS FOR WHITENING TEETH

(WO2000028953) 25.05.2000 A61C 19/06 ULTRADENT PRODUCTS, INC.
Composition and methods that include potassium nitrate for reducing tooth sensitivity and a dental bleaching agent, such as hydrogen peroxide or carbamide peroxide. The dental compositions (10) may be applied directly to the person's teeth (18), or they may be loaded into a comfortable fitting, flexible, thin-walled dental tray (22) and placed over the person's teeth (18). In that case, the dental compositions (10) will include a tackifying agent, such as carboxypolymethylene, which assists the composition (10) in retaining the dental tray (22) over the person's teeth (18) as a result of the adhesive properties of the dental composition rather than due to mechanical interlocking or fit of the tray over the person's teeth. The dental composi...
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DENTAL ETCHING COMPOSITION

(WO2000028946) 25.05.2000 A61K 6/00 MINNESOTA MINING AND MANUFACTURING COMPANY
Dental etching compositions are provided that have the capability of undergoing an increase in viscosity in response to an increase in temperature. In a preferred embodiment, the compositions also have the ability to reverse their viscosity in response to a decrease in temperature.
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CONNECTING ELEMENT FOR PILE-PLANKS

(WO2000028157) 18.05.2000 E02D 5/08 WALL, Georg
According to the invention, the connecting element for pile-planks is an extruded section with a hooked strip (5) whose cross-section extends approximately in the shape of a semicircle or a sickle and whose end section (7) points at a bearing surface (11) on a central segment (3) of the connecting element. The dimensions of the mouth opening (8), which is delimited by the end section and the bearing surface, and the hooked strip (5) are such that a hooked strip (9) of a conventional pile-plank (10) can pivot in the hooked strip (5) of the connecting element but cannot jump out of the hooked strip by displacement or pivoting.
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METHOD OF GENERATING AQUEOUS SILICA NETWORK PARTICLES AND COMPOSITIONS INCLUDING THE SILICA NETWORK PARTICLES

(WO2000028113) 18.05.2000 A61K 8/25 INTEGRITY TECHNOLOGIES, LLC
An aqueous composition including silica particles with a particle size distribution and particle structure that improve the water retention and exchange characteristics of the aqueous composition is provided. The aqueous silica composition includes silica network particles and water. The silica network particles comprise main particles and bridging particles that form chains between adjacent main particles. The main particles have a particles' size greater than the particle size of the bridging particles. Because of the presence of the silica network particles, the aqueous composition is capable of wetting a hydrophobic substrate more than pure liquid water. The silica network particles are generated in water by a method in which an aqueous...
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ORAL COMPOSITION EXHIBITING IMPROVED UPTAKE OF ANTIBACTERIAL COMPOUNDS

(WO2000025737) 11.05.2000 A61K 8/34 COLGATE-PALMOLIVE COMPANY
The invention provides an antibacterial oral composition containing an antibacterial compound, a monoalkyl phosphate compound and another anionic surfactant; whereby, the antibacterial effect on dental tissue is substantially increased due to the combined presence of the monoalkyl phosphate compound and the other anionic surfactant in a given weight ratio.
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ORAL CAVITY CLEANING DEVICE

(WO2000025699) 11.05.2000 A46B 11/06 RICOH ELEMEX CORPORATION
An oral cavity cleaning device comprising a cleaning head (60) and a liquid discharge tank (B) connected with each other via a liquid discharge tube (25), and a throttle means (61) provided on a disposal flow passage extending from the tip (60a) of the cleaning head (60) to the suction port (b) of the liquid discharge tank (B) and throttling the disposal flow passage, wherein the cleaning head (60) is inserted into the oral cavity with a pump (A) driven and residue in the oral cavity is sucked into the liquid discharge tank (B) to clean the inside of the oral cavity. When a normal suction force is not strong enough to suck the residue, the disposal flow passage throttled by the throttle means (61) increases a negative pressure in the liquid...
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ANTIMICROBIAL COMPOSITIONS THAT PROTECT SKIN AND DENTAL TISSUE

(WO2000025697) 11.05.2000 A61K 8/34 NATHOO, Salim, A.
Disclosed are compositions containing at least one anti-microbial agent and at least one volatile solvent. The compositions are applied to biological substrates such as skin, keratinous tissue (e.g., finger nails and toenails) and dental tissue (e.g., teeth and surrounding soft tissue). A residue of the anti-microbial agent is left on the substrate, inhibiting microbial growth for a given period of time. The compositions are particularly useful in the course of dental procedures. In these embodiments, they are applied to teeth that have been drilled or otherwise prepared to receive a dental restorative composition such as a filling or crown, or a dental prosthetic device.
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A CONTINUOUS DENTAL FLOSS AND A CONTAINER FOR STORAGE AND DELIVERY THEREOF

(WO2000021459) 20.04.2000 A61C 15/04 ZASCHERINSKY, Dmitry Anatolievich
Continuous dental floss comprising cleaning sections and cut-off sections where the dental floss is to be cut alternating along its entire length further comprises floss holding elements in the form of plastic balls which are mounted along the entire length of the dental floss and separate cleaning sections and cut-off sections, the length of cleaning sections exceeding the length of cut-off sections. The objective of the invention is attained also by provision of a container for storage and delivery of continous dental floss comprising a body having a dental floss outlet opening and a dental floss cutting means, and a means for winding continous dental floss located inside the body.
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DENTAL ARTICULATOR AND ITS TRANSFORM PLATE

(WO2000021457) 20.04.2000 A61C 11/06 FUJITA, Kazuya
A dental articulator (5) capable of reproducing or analyzing a physiological occlusion status by implementing a pressure receiving function and a traction function capable of operating in all the motion directions equivalently provided by a jaw joint function of a living body with a teeth plaster model fitted between upper and lower jaw frames, comprising an occlusal plane table (8) having the same anteversion angle as the occlusal plane oblique angle of a living body; a bite analysis plate (9) on which average positions of a spew center (91) and a posterior motion axis (92) are set at a plurality of positions and they are sketched in pairs with the average positions of the spew center on one side and those of the posterior motion axis on t...
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METHOD AND DEVICE FOR PREPARING A DENTAL IMPLANT BY IMMERSION IN A MESENCHYMAL CELL CULTURE

(WO2000021456) 20.04.2000 A61C 8/00 SOCIETE ANONYME NATURAL IMPLANT
The invention concerns a method for making a dental implant consisting in: preparing an implant consisting of a radicular part and a coronal part and made from a biocompatible inert material corresponding in shape to an extracted tooth; immersing said implant radicular part in a culture of undifferentiated mesenchymal cells, in a culture medium whereof the composition enables the differentiation in cementoblasts and in fibroblasts, for a duration sufficient for said differentiation, for the cement blasts to adhere on said radicular part, for a first layer of cement and a alveolar-dental ligament attached to said cement to be formed; collecting the implant bearing differentiated tissues fixed on its radicular part.
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APPARATUS AND METHOD FOR PARTICLE FEEDING BY PRESSURE REGULATION

(WO2000021452) 20.04.2000 A61C 3/025 KREATIV, INC.
The invention enables accurate control of particle flow with regard to feeding abrasive material to a surface. The unit does not employ a vibrator and may be used to remove undesired material from a surface. A particular application is in a dental air abrasion unit for both cleaning and cutting tooth surfaces. When used in an air abrasion dental instrument, the abrasive material is stored in a container which is separated from a mixing chamber by an orifice member. The flow of particles is electronically controlled by the differential in pressure in the container section above the particle level and the pressure below an orifice member in a mixing chamber. The resulting particle flow to the surface is substantially linear and less erratic t...
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DENTAL COMPOSITION BASED ON SILICONE CROSSLINKABLE BY CATION PROCESS

(WO2000019967) 13.04.2000 A61K 6/093 RHODIA CHIMIE
The invention concerns dental compositions. Said composition comprises (1) a silicone crosslinkable and/or polymerisable by cation process; (2) an efficient amount of at least an initiator such as onium borate; (3) at least a photosensitizer; and (4) a dental filler present in the composition in a proportion of at least 10 wt. % relative to the composition total weight. Said dental compositions are useful for making dental prostheses or for dental restoration.
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DENTAL COMPOSITION BASED ON SILICONE CROSSLINKABLE BY CATIONIC PROCESS

(WO2000019966) 13.04.2000 A61K 6/093 RHODIA CHIMIE
The invention concerns dental compositions. Said dental composition comprises (1) a silicone crosslinkable and/or polymerisable by cationic process; (2) an efficient amount of at least an initiator such as an organometallic complex borate; and (3) a dental filler present in the composition in a proportion of at least 10 wt. % relative to the composition total weight. Said dental compositions are useful for making dental prostheses or for dental restoration.
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CLEANING COMPOSITIONS FOR MEDICAL INSTRUMENTS

(WO2000018858) 06.04.2000 C11D 1/66 MACGREGOR, Keith, Martin
The present invention concerns a composition and a method for cleaning instruments and the like. More particularly, it is concerned with compositions for removal of body fluid from surgical instruments and other surfaces such as operating tables and instrument trays.
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FAST DISSOLVING ORALLY CONSUMABLE FILMS

(WO2000018365) 06.04.2000 A61K 8/02 WARNER-LAMBERT COMPANY
Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, methyl salicylate, eucalyptol and menthol. The edible films are effective at killing the plaque-producing germs that cause dental plaque, gingivitis and bad breath. The film can also contain pharmaceutically acitve agents. Methods for producing the films are also disclosed.
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COMPOSITION AND METHOD FOR WHITENING TEETH WITHOUT DAMAGING SOFT TISSUE

(WO2000016737) 30.03.2000 A61K 7/20 MCLAUGHLIN, Gerald, G.
A composition is provided for whitening a tooth in a dental arch, including at least 30 % by weight of potassium hydrogen peroxymonopersulfate sulfate (2KHSO5?.KHSO4?.K2?SO4?) in a slurry or in a dry form, wherein the composition does not cause damage visible to the naked eye to a soft tissue during a treatment period. A composition is also provided for whitening a tooth including at least 30 % by weight of potassium hydrogen peroxymonopersulfate (2KHSO5?.KHSO4?.K2?SO4?) in a slurry or dry form, wherein the composition does not include a peroxide bleaching agent. In another embodiment, a method is provided for whitening a tooth in a dental arch. The method includes (1) contacting the dental arch with a composition comprising...
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CALCIFIED TISSUE FACING PREPARATION CONTAINING AN ANTIMICROBIAL AGENT

(WO2000016712) 30.03.2000 A61K 6/083 ADVANTAGE DENTAL PRODUCTS, INC.
The present invention provides a calcified tissue facing preparation characterized by having a polymerizable resin, and an antimicrobial agent of formula (I) where R1? is a hydrocarbon radical having between 1 and 16 carbon atoms, n is an integer between 1 and 8 inclusive and X is a halogen atom selected from fluorine, chlorine or bromine. It is appreciated that R1? includes unsaturated hydrocarbon radicals, as well as heteroatom containing radicals. Preferably, the molecule of formula (I) is associated with an adduct species. A solvent and the complementary spectrum antimicrobial benzalkonium chloride are also optionally added. An antimicrobial oral rinse excluding the polymerizable resin contains at least 0.2 % by weight of the antimi...
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LOW TEMPERATURE NON-CRYSTALLIZING LIQUID XYLITOL COMPOSITIONS AND CO-HYDROGENATION PROCESSES FOR MAKING SAME

(WO2000015236) 23.03.2000 A23G 3/34 SPI POLYOL, INC.
A liquid xylitol composition that is non-crystallizing at low temperatures comprising, at between about 65 and about 90 weight percent dry solids, xylitol, in an amount between about 65 and about 90 weight percent of the dry solids, and sorbitol, in an amount between about 10 and about 35 weight percent of the dry solids. This liquid xylitol composition is preferably non-crystallizing at between about 0 C and about 10 C. A process for producing liquid xylitol compositions, comprising co-hydrogenating a sugar syrup mixture comprising a sugar syrup having a dextrose equivalence (DE) of between about 20DE and about 99DE, in an amount between about 5 and about 35 weight percent of the mixture, and xylose, in an amount between about 65 and a...
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IMPROVED ENDOSCOPIC METHOD AND DEVICE FOR SUBGINGIVAL DENTAL PROCEDURES

(WO2000015136) 23.03.2000 A61B 1/24 INTERNATIONAL BIOVIEW, INC.
This invention is an improved endoscopic system (100) for visualizing subgingival dental procedures. The device comprises a dilator projection (102) incorporated into or onto the body of a dental instrument (10) utilized to remove plaque, and calculus from subgingival tooth surfaces. The projection (102) preferably comprises a thin, flat shield portion (104) having an arcuate shank portion (106) extending therefrom. In use, the shield portion (104) of the dilator projection (102) is operative to dilate or spread the gingiva away from the adjacent tooth surfaces upon which the dental instrument (10) is utilized to remove plaque, and calculus. Formed within the shank portion (106) of the dilator projection (102) is at least one lumen for rece...
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NON-CRYSTALLIZING LIQUID XYLITOL COMPOSITIONS AND CO-HYDROGENATION PROCESSES FOR MAKING SAME

(WO2000015048) 23.03.2000 A23G 3/34 SPI POLYOL, INC.
A non-crystallizing liquid xylitol composition comprising, at between about 65 and about 90 weight percent dry solids, xylitol, in an amount between about 10 and about 50 weight percent of the dry solids, and sorbitol, in an amount between about 50 and about 90 weight percent of the dry solids. The liquid xylitol composition is preferably non-crystallizing at between about 0 C and about 10 C. A co-hydrogenation process for producing liquid xylitol compositions, comprising co-hydrogenating a sugar syrup mixture comprising a sugar syrup having a dextrose equivalence (DE) of between about 20DE and about 99DE, in an amount between about 55 and about 95 weight percent of the mixture, and xylose, in an amount between about 15 and about 55 wei...
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DENTAL SUCTION MIRROR

(WO2000012025) 09.03.2000 A61B 1/247 MIRAE T &G CO., LTD.
A dental suction mirror including: a stainless reflecting plate (10) having a slant depression (12) in the front portion thereof, an oblong groove (13) in the rear portion thereof and three holes having different paths in the inner center and on both sides thereof; a stainless connection tube (20) having an expanding portion (21) in the fore portion thereof and a projecting tube in the rear portion thereof; and a handle tube (30) having an insertion groove along the upper part thereof so as to connect the stainless reflecting plate (10) and the stainless connection tube (20), an optical fiber (50) being inserted into the insertion groove (31), stickers being applied to the groove so as to prevent the optical fiber from being getting out of ...
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DENTAL INSTRUMENT

(WO2000012022) 09.03.2000 A61C 3/02 MEDITEAM DENTALUTVECKLING I GTEBORG AB
The invention relates to a dental instrument for removing caries attacked dentine in connection with chemical-mechanical treatment of caries by means of a caries-dissolving solution applied to the caries for loosening the caries tooth substance. The instrument comprises a tool head (1) with a number of scraping edges or bristles (2, 5, 9) for scraping away the loosened caries tooth substance. In the spacings (2', 9') formed therebetween drops of the gel solution used for the chemical-mechanical treatment can be carried (transported) up to the tooth treatment site. In contrast to previous scraping instruments of this type the instrument is power-driven in order to provide the tool head (1) with a predetermined scraping motion. Preferably the...
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METHODS AND COMPOSITIONS FOR TREATING PERIODONTAL DISEASE WITH AN INHIBITOR OF SECRETORY PHOSPHOLIPASE A2?

(WO2000010568) 02.03.2000 A61K 9/00 DRAHEIM, Susan, E.
The present invention relates to methods of treating periodontal disease in a mammal. The methods include administering to an animal an effective amount of an inhibitor of sPLA2?. The inhibitors may be advantageously delivered as a composition that includes various carriers. In certain aspects of the invention, inhibitors used in the method include substituted indole or substituted pyrrole sPLA2? inhibitors. Also provided are compositions that include the sPLA2? carriers for oral delivery of the inhibitors.
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TOOTHPASTE COMPRISING FINE AND COARSE CALCIUM CARBONATE

(WO2000010520) 02.03.2000 A61P 1/02 UNILEVER N.V.
The present invention relates to a toothpaste which comprises particulate calcium carbonate as the main abrasive cleaning agent. By using a mixture of relatively fine particulate calcium carbonate with a certain level of relatively coarse particulate calcium carbonate, the toothpaste provides for a reduced RDA while maintaining the same cleaning efficacy in comparison with the use of only the relatively fine particulate calcium carbonate.
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ANTIBODIES FOR USE IN TARGETED AND TEMPORARY TREATMENT OF HUMANS AND ANIMALS

(WO2000009164) 24.02.2000 A61K 47/48 WOUTERS, Stanislaus, Laurens, Johan
The invention relates to an antibody, or a fragment of an antibody, which binds to an epitope under specifically chosen conditions, and the binding of which to that epitope is broken under specifically chosen different conditions, in addition to an antibody or fragment thereof with which a diagnostically, therapeutically or cosmetically active substance is optionally conjugated, for targeted and temporary diagnostic, therapeutic or cosmetic treatment of externally accessible parts of the human and animal body, wherein both the specifically chosen binding conditions and the conditions wherein the binding is broken lie within physiologically acceptable limits and are formed by the pH and/or ion strength. The invention further relates to the u...
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INCORPORATION OF EXOGENOUS LACTIC BACTERIA INTO THE ORAL MICROFLORA

(WO2000009080) 24.02.2000 A23C 9/123 SOCIETE DES PRODUITS NESTLE S.A.
The use of lactic bacteria that is not part of the resident microflora of the mouth, and that is low acidifying and is capable of adhering directly to the pellicle of the teeth for the preparation of a composition intended for the prophylaxis or the treatment of dental caries, dental plaque and periodontal infection and compositions prepared therewith.
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METHODS AND COMPOSITIONS FOR WHITENING TEETH

(WO2000009079) 24.02.2000 A61K 7/20 MCLAUGHLIN, Gerald, G.
The invention provides a composition for whitening teeth, using a non-peroxide ionic bleaching compound. The compositions are made into various consistencies and forms such as pastes, gels, or solutions such that they can be placed in contact with teeth or a dentrifice to be treated. Ions and radicals in the materials penetrate into the tooth structure and cause a whitening effect both on the surface and below the surface. A method for whitening teeth by providing a bleaching agent or compositions to teeth or a dentrifice to be treated is also provided.
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EXTENSIBLE POLISHING MONO-FILAMENT DENTAL FLOSS,

(WO2000009034) 24.02.2000 A61C 15/04 ATHENA NORDIC AB
Monofilament dental floss/tape of polymer material including fluoride and polishing powder, the dental floss/tape (1) being ribbon-shaped and having material properties that enable it to be stretched to increase its length by at least 100 % and also to reduce its cross-sectional area by up to ten times, and also a method for the use of monofilament polymer dental floss/tape (1) by preparing a suitable length of dental floss/tape (1) for cleaning the teeth, by extending it to a reduced cross section so that the area or the whole piece of floss/tape can thereafter be used to clean the teeth distally and/or mesially.,
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DEVICE FOR PHOTOPOLYMERIZING COMPOSITE MATERIALS USED IN THE DENTAL FIELD

(WO2000007517) 17.02.2000 A61C 13/15 DMDS LTD.
Device for photopolymerizing composite materials used in the dental field and for bleaching or whitening teeth. Said device includes a box containing a light source controlled by an electronic circuit and a light wave guide adapted to be optically coupled to the box. An interchangeable joining piece is coupled to the free end of the light wave guide. Optical filters in a special housing can be connected to one or the other end of the light wave guide, making it possible to obtain at the outlet of the joining piece a light with a spectral band ranging from 250 to 750 nm.
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ANTI-CARIOGENIC MILK PRODUCT AND USE

(WO2000007454) 17.02.2000 A23C 9/12 SOCIETE DES PRODUITS NESTLE S.A.
The invention concerns the use of a rennet milk in sufficient amount for preparing refrigerated food compositions for preventing or treating dental caries or plaque and the resulting compositions.
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ELECTRONIC GAS-LIGHTING DEVICE

(WO2000007217) 10.02.2000 F23Q 3/00 MILLER EUROPE S.P.A.
A connecting board carrying an electric circuit and extending the full length of the cup-shaped body is positioned substantially closing the mouth, inside an inner casing cavity, and carries, on a first face all the electronic pulse generating means connected mechanically and electrically to one another and to the board by the board itself and the circuit, so as to be housed in one continuous compartment defined by the cavity and by the connecting board, so as to be embedded, together with the connecting board, in a matrix of insulating polymer resin which fills the whole of the cavity up to a point substantially flush with the mouth of the cavity.
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APPARATUS AND METHODS FOR CONCENTRATING LIGHT THROUGH FIBER OPTIC FUNNELS COUPLED TO DENTAL LIGHT GUIDES

(WO2000007068) 10.02.2000 A61C 13/15 ULTRADENT PRODUCTS, INC.
An apparatus for concentrating the amount of light transmitted from a light guide to activate hardenable materials. The apparatus comprises a fiber optic funnel (100) and a coupler (110) for coupling the fiber optic funnel to a light guide (120). The guide is also coupled to a radiant energy source or light source from which the guide receives radiant energy or light. This configuration enables radiant energy to be directed from the radiant energy source through the guide and then through the fiber optic funnel to a hardenable or photocurable material to provide concentrated amounts of radiant energy to the hardenable material. Accordingly, radiant energy may be concentrated to initiate hardening of a hardenable composition on a tooth surfa...
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CARRAGEENAN COMPOSITIONS, AND PROCESSES FOR THEIR PRODUCTION

(WO2000006609) 10.02.2000 A23L 1/0532 HERCULES INCORPORATED
Carrageenan compositions comprising from about 79 mol% to about 95 mol% iota carrageenan and from about 0.1 mol% to about 10 mol% nu carrageenan, and carrageenan compositions which exhibit elastic modulus, G'-1 Hz at 5 C, of greater than about 200 Pa, elastic modulus, G'-1 Hz at 25 C, of less than about 200 Pa, viscous modulus, G''-0.2Hz at 5 C, of from about 5 Pa to about 25 Pa, and melting point of less than 60 C, in a 1.2 wt.% aqueous gel, and methods of producing the same.
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MULTI-USE HEATING DEVICE FOR VAPORIZING ACTIVE SUBSTANCES

(WO2000006212) 10.02.2000 A01M 1/20 DBK ESPAA, S.A.
The device comprises a body (1) wherein is arranged an electric resistance (3) connected to two contacts (2) emerging through the bottom of the body (1) and associated to an aluminium plate (5) acting as a radiator and remaining fixed internally in correspondence with the upper part of the body (1) and retained by means of lugs (6). The body (1) and the aluminium plate (5) present a hole (7) through which is passed a wick which emerges through the mouth of a container filled with liquid product, for its vaporization, through heating of the wick by means of the electric resistance. A frame-like separator (8) is arranged on the body (1) with means for fixing the separator to the body (1) and forming a support surface for a small board (12); t...
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ANTIBIOTIC TOOTHPASTE

(WO2000006208) 10.02.2000 A61K 8/22 HEALTHSHIELD TECHNOLOGIES L.L.C.
An antibiotic toothpaste is formulated with an inorganic antibiotic metal containing composition that is present in an amount effective to impart substantial antimicrobial activity within the normal time for brushing teeth.
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TEETH CREVICE CLEANING APPARATUS AND METHOD OF USING THE SAME

(WO2000006045) 10.02.2000 A61C 15/00 CHEN &CHEN, LLC
A mouth pad (2) for cleaning teeth crevices has a U-shaped plate (1) sized to cover substantially only the biting surfaces of upper and lower teeth of a human jaw. The plate (1) is positioned between the upper teeth and lower teeth such that when the teeth are rinsed with a liquid, the liquid flows primarily through the crevices between individual teeth, and physically detaches the adhering residue within. A method of cleaning teeth using a plate (1) positioned between the upper, and lower teeth is also disclosed.
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STERILIZATION USING LIQUID CARBON DIOXIDE AND UV-IRRADIATION

(WO2000004932) 03.02.2000 A61L 2/10 RAYTHEON COMPANY
A process is provided for cleaning, disinfecting, and sterilizing substrates comprising the steps of: (a) placing the contaminated substrate in a cleaning vessel; (b) contacting the contaminated substrate with dense phase carbon dioxide in liquid form; (c) subjecting the substrate and the dense phase carbon dioxide to ultraviolet radiation having a wavelength within the range of about 180 to 300 nm for a duration and intensity sufficient to produce a photochemical reaction capable of destroying the DNA of microorganisms on the substrate; (d) substantially simultaneously subjecting at least the dense phase carbon dioxide to agitation; and (e) removing the dense phase carbon dioxide from the cleaning vessel and thereby transporting the contam...
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POROUS CERAMIC

(WO2000002830) 20.01.2000 C04B 38/00 NERLICH, Michael
The invention relates to porous ceramics which are produced by: a) mixing an aqueous solution of a suited ionotropic orientationable polyanion with either oxides or hydroxides or oxide hydrates, in the form of sol, of metals Al, Zr, Ti, and Nb; or with the finely crystalline oxides or hydroxides or oxide hydrates of these metals which are contained in a suspension; or with finely crystalline tricalcium phosphate or apatite contained in a suspension; b) bringing the mixed sol/suspension obtained according to a) into contact with the solution of a salt of a bivalent or trivalent metal cation for producing an ionotropic gel body; c) compacting the gel body by introducing electrolyte solutions; d) rinsing with water and impregnating with a read...
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ORAL COMPOSITION EXHIBITING ENHANCED ANTIPLAQUE EFFICACY

(WO2000002527) 20.01.2000 A61K 8/34 COLGATE-PALMOLIVE COMPANY
A composition and method for the treatment and prevention of plaque accumulation on teeth wherein there is administered to the oral cavity and oral composition comprising an orally acceptable aqueous vehicle containing an effective therapeutic amount of a noncationic antibacterial agent and an acrylic polymer/polyoxyalkylene copolymer formed from about 80 to about 90 % by weight of the acrylic polymer and about 5 to about 20 % by weight of the polyoxyalkylene having a molecular weight greater than 4,000 and less than 20,000 the antibacterial compound exhibiting increased antiplaque activity on dental tissue.
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MUCOSAL TARGETING IMMUNISATION

(WO2000000218) 06.01.2000 A61K 9/00 AVENTIS PASTEUR
The invention concerns the use of an immunogen specific of a pathogenic agent with a gateway in the buccal mucous membrane region, for producing a vaccine composition to be administered in the floor of the mouth in a human being so as to develop directly a local response in IgA antibodies and in B cells secreting IgA in the buccal mucous membrane, saliva and ganglions draining said mucous membrane. The invention also concerns a vaccine composition capable of being applied in the floor of the mouth in a human being to induce local and systemic immunity in IgA antibodies, substantially consisting of a material adhering or not to the buccal mucous membrane and containing an immunogen specific of the pathogenic agent with a gateway into the buc...
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SYNTHETIC PEPTIDE VACCINES FOR FOOT-AND-MOUTH DISEASE

(WO1999066954) 29.12.1999 A61K 39/00 UNITED BIOMEDICAL INC.
The present invention relates to the use of a peptide composition as an immunogen, with each peptide contained therein comprising a target antigenic site derived from the VP1 capsid protein of Foot-and-Mouth Disease Virus (FMDV). The antigenic site is covalently linked to a helper T cell epitope and, preferably, to other immunostimulatory sequences, preferably by conventional peptide bond(s) through direct synthesis, for the prevention of FMDV infection and eradication of Food-and-Mouth Disease (FMD). More particularly, the present invention relates to the use of such peptide composition as an immunogen to elicit the production in animals including swine, cattle, sheep, goets and susceptible wild species, of high titer polyclonal antibodies...
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LIQUID DISPENSER

(WO1999066140) 23.12.1999 E03D 9/03 S.C. JOHNSON &SON, INC.
A liquid dispenser (1) comprises a housing (2) and a hook (3) for suspending the housing (2) from the rim of a lavatory bowl. A user insers a sealed inverted reservoir bottle (6) into the housing (2), which breaks the seal. A porous pad (7) located in the housing (2) conveys liquid from the bottle (6) to a position within the stream of flushing water. The pad (7) can be adjusted to accommodate different lavatories and has two guide slots which are engaged by two fingers in the housing which define two extreme positions of the pad (7). To allow venting of the bottle (6), small vent holes (14) are formed in the pad (7). The pad may alternatively be a solid plate of the same shape but having a number of raised holes or elongate slots. The plat...
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DISPENSING LIQUIDS

(WO1999066139) 23.12.1999 E03D 9/03 S.C. JOHNSON &SON, INC.
A liquid dispenser (1) comprises a housing (2) and a hook (3) for suspending the housing (2) from the rim of a lavatory bowl. A user inserts a sealed inverted reservoir bottle (6) into the housing (2), which breaks the seal. A porous pad (7) located in the housing (2) conveys liquid from the bottle (6) to a position within the stream of flushing water. The pad (7) can be adjusted to accommodate different lavatories and has two guide slots which are engaged by two fingers in the housing which define two extreme positions of the pad (7). To allow venting of the bottle (6), small vent holes (14) are formed in the pad (7). The pad may alternatively be a solid plate of the same shape but having a number of raised holes or elongate slots. The pla...
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PROCESS FOR FORMING CHEWABLE QUICKLY DISPERSING MULTI-VITAMIN PREPARATION AND PRODUCT THEREFROM

(WO1999065473) 23.12.1999 A23G 3/00 FUISZ TECHNOLOGIES LTD.
A composition and method for preparing comestible units which disperse quickly in the mouth, especially when chewed, includes initiating crystallization of shearform matrix with crystallization/binding promoter and combining with an additive to form flowable, compactible micro-particulates. The combination is then shaped to form a comestible unit having high structural integrity, good appearance, and excellent release characteristics which is suitable for pharmaceutical and nutraceutical applications.
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SMOKERS' ARTICLE

(WO1999065343) 23.12.1999 A24D 1/04 POGOSYAN, Seiran
The present invention relates to a smokers' article that comprises a filter, a tobacco rod (2) enclosed in a sheath (1) as well as a mouthpiece (3) connected to said tobacco rod. The tobacco rod (2) is enclosed in a sheath made of cigarette paper, while the mouthpiece (3) is made of carton or paper treated with a plasticiser. The ratio between the length of the mouthpiece and that of the tobacco rod (2) is equal to 0.4 - 1.5. The filter (4) comprises at least two parts arranged serially, wherein one part is made of a fibrous material while the other comprises active-carbon particles. The filter is arranged at a distance of at least 0.01 m relative to the mouth end of the article. The mouthpiece (3) is connected to the tobacco rod (2) by a l...
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BLENDED NUT SPREAD COMPOSITIONS

(WO1999065339) 23.12.1999 A23L 1/38 THE PROCTER &GAMBLE COMPANY
Nut spreads, especially peanut butter compositions, comprising a blend of mono-modal and multi-modal compositions. The blended peanut butters have a relatively low viscosity, yet avoid an oily appearance and greasy mouth feel. A product composition and method for making the product composition are disclosed.
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METHOD OF MAKING HEAT-RESISTANT CHOCOLATE AND CHOCOLATE-LIKE COMPOSITIONS WITH REDUCED APPARENT VISCOSITY AND PRODUCTS MADE THEREBY

(WO1999065323) 23.12.1999 A23G 1/00 DAVILA, Victor, R.
A heat-resistant chocolate or chocolate-like composition is prepared by mixing a polyol, such as sorbitol or glycerine, with a flowable chocolate or chocolate-like composition through an increased apparent viscosity phase. Upon continued mixing, the mixture returns to a reduced apparent viscosity (fluid) phase. The mixture is subsequently handled in the same manner as an unmodified composition. Upon aging and stabilization, the modified chocolate or chocolate-like composition demonstrates a reduced tendency to deform at elevated temperatures, is less prone to stick to packaging or fingers, and maintains the desired flavor, texture, mouth feel, and other characteristics of ordinary chocolate. The heat-resistant chocolate or chocolate-like co...
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CLEAR DENTRIFRICE GELS

(WO1999063960) 16.12.1999 A61K 8/24 THE PROCTER &GAMBLE COMPANY
According to the present invention there is provided a visually clear, dentrifice gel comprising; a) sufficient tetrasodium pyrophosphate to provide from 0.2 % to 5 % pyrophosphate anion; b) a silica dental abrasive having a refractive index of from 1.445 to 1.47; c) from 0.7 % to 3 % sodium alkyl sulphate; and d) an aqueous liquid carrier. The gel has excellent clarity, high anticalculus efficiency and good foaming. According to a further aspect of the invention there is provided a process for making a clear dentifrice gel comprising the step of adding anhydrous tetrasodium pyrophosphate to an aqueous carrier, the gel comprising: a) a silica dental abrasive having a refractive index of from 1.445 to 1.47; and b) an aqueous liquid carrier c...
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VERY HIGH VISCOSITY POLYVINYLSILOXANE IMPRESSION MATERIAL

(WO1999062461) 09.12.1999 A61K 6/10 DENTSPLY INTERNATIONAL INC.
Improved very high viscosity (putty) two component polymerizable polyorganosiloxane composition for use in making dental impressions, having improved tear strength, handling and wettability. Improved tear strength results from inclusion of a quadri-functional polysiloxane having a vinyl content of 0.16 to 0.24 m-mole/g. Working time is maintained by including sufficient amounts of a retarder composition that delays onset of the vinyl polymerization. Handling is improved by the addition of a very high viscosity linear vinyl terminated polydimethylsiloxane which reduces tackiness and improves the shelf stability. Wettability is improved by including a surfactant resulting in a surface contact angle with water at three minutes of less than 50..
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PHOTOPOLYMERIZABLE DENTAL COMPOSITIONS

(WO1999062460) 09.12.1999 A61K 6/087 MINNESOTA MINING AND MANUFACTURING COMPANY
Photopolymerizable compositions that include free radically active and cationically active functional groups, and methods for polymerizing such compositions, in which the onset of cationic polymerization is controllably delayed to extend the time between formation of a moldable gel and formation of a hardened solid.
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ARTICLE COMPACTING DEVICE

(WO1999061231) 02.12.1999 B26F 1/24 TOMRA SYSTEMS ASA
An apparatus for the compaction of articles, e.g., disposable metal cans or disposable plastic bottles, consisting of a pair of mutually counter-rotatable, interacting squeeze rollers (6', 7'; 14', 15'), wherein the first roller (7'; 15') has a fixed support and wherein the second roller (6'; 14') is supported in an arm-spring assembly (39, 39'; 40, 40'), thereby enabling the space between the rollers to be varied according to the size and compactability of the article. In addition, the apparatus has a precompactor consisting of a conveyor (35), e.g., a belt or chain conveyor, and an elongate press plate (36) inclined relative to the conveyor and preferably spring-loaded, to ensure that the article is gradually flattened upstream of the squ...
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DENTAL DEVICE

(WO1999060946) 02.12.1999 A61C 5/12 JANSE VAN RENSBURG, Frederick, Cornelius
The invention relates to a dental device including matrix retainer band (40) and to dental methods using the matrix retainer band. The band (40) comprises a translucent portion (12), for example, in the form of a strip of flexible translucent plastics material, the translucent portion (12) being configured to be locatable around a tooth thereby maintaining the tooth anatomy while providing a dentist with a substantially unobstructed view of the dental work in progress. The thickness (32) of the band (40) is selected to permit passage thereof between adjacent teeth. In some embodiments, adhesive portions (36 and 38) are provided to retain the band (40) around a tooth. The invention also provides methods of using the band (40) in performing a...
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ORALLY DISINTEGRABLE TABLETS

(WO1999059544) 25.11.1999 A61K 9/00 TAKEDA CHEMICAL INDUSTRIES, LTD.
An orally disintegrable tablet, of the present invention, which comprises (i) fine granules having an average particle diameter of 400 $g(m)m or less, which fine granules comprise a composition coated by an enteric coating layer, said composition having 10 weight % or more of an acid-labile physiologically active substance and (ii) an additive, has superior disintegrability or dissolution in the oral cavity so that it can be used for treatment or prevention of various diseases, as an orally disintegrable tablet capable of being administered to the aged or children and easily administered without water. Also, because the tablet of the present invention contains fine granules having the average particle diameter such that it will not impart r...
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ODOUR ABSORBING AGENT

(WO1999059539) 25.11.1999 A61K 8/04 THE BOOTS COMPANY PLC
The present invention provides a composition comprising an acceptable diluent or carrier and high surface area zinc oxide, having a surface area between 30 m?2/g and 100 m?2/g and a particle size between 0.1 and 200 $g(m)m, said high surface area zinc oxide being present in an amount sufficient to absorb odour. The compositions may be for cosmetic or oral use and may be used to treat bad breath and body odour in humans.
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SYSTEM FOR OPTIMIZED FORMATION OF FLUORAPATITE IN TEETH

(WO1999059496) 25.11.1999 A61B 5/00 AB GRUNDSTENEN 85182
The invention consists of a system comprising a measuring device of shape adapted to the tooth, which with yellow, green and blue colour grades the current pH value in the patient's tooth film and in which the green colour indicates the optimum pH value for the formation of caries-counteracting fluorapatite. Three types of colour-matching tubes of toothpaste have compositions that contain fluoride and centre the pH values of the tooth films on the green level. The system's measuring device shows by colorimetric means which toothpaste will at that precise time best promote the formation of fluorapatite in each of the three pH groups from which the device selects.
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TOOTHBRUSH WITH FLUORESCENCE MEANS FOR LOCATING DENTAL PLAQUE

(WO1999059462) 25.11.1999 A46B 15/00 HELMUT HUND GMBH
An apparatus for detecting biological deposits on the surface of a tooth. The device has illumination means to direct exciting radiation onto a test tooth surface and detection means to detect fluorescence emission from the test tooth surface at a wavelength associated with that of auto fluorescence emission from clean tooth surface. The intensity of the said fluorescence emission from the test tooth surface is compared with an intensity of auto fluorescence emission from clean tooth surface and the comparison is associated with the presence of deposits on the test tooth surface. The device is preferably embodied in a toothbrush which indicates to the user that deposits are present and are being removed.
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CO-PROCESSED COMPOSITIONS OF ACIDS AND WATER SOLUBLE CRYSTALLINE COMPOUNDS AND RELATED PRODUCTS AND METHODS

(WO1999059427) 25.11.1999 A23G 3/00 SPI POLYOLS, INC.
The invention includes co-processed compositions containing at least one acidulent and at least one water-soluble crystalline compound for use in shelf-stable low-moisture comestible, confectionery, dentifrice, or pharmaceutical products containing acid-sensitive additives. The invention also includes methods of minimizing the degradation of an acid-sensitive additive by at least one acidulent in low-moisture comestible, confectionery, dentifrice, or pharmaceutical products that contain at least one acidulent by using the co-processed compositions of the present invention. The invention also includes methods of increasing salivation and methods of removing or preventing the deposition of plaque on teeth using the co-processed compositions o...
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FRIED FOOD AND SHORTENING

(WO1999059424) 25.11.1999 A21D 13/08 KAO CORPORATION
A fat composition is provided containing 55 to less than 95 % by weight of diglycerides, in which 55 to less than 93 % by weight of the fatty acid groups present are unsaturated fatty acid groups, and a shortening composition containing the fat composition, as well as fried foods containing the fat composition, wherein the shortening is reduced in bubbling during deep frying, and the fried food gives a satisfactory feeling in the mouth and improved crispiness.
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DEVICE FOR MEASURING THE ROTATIONAL SPEED OF FLUID-DRIVEN DRIVE MECHANISMS

(WO1999058984) 18.11.1999 A61C 1/05 OTT, Josef
The invention relates to a sensor (5) provided for measuring the rotational speed of a fluid-driven drive mechanism, particularly of a turbine wheel (1), especially of a pressurized-air operated turbine wheel of a dental device. Said sensor is arranged on a return line (4) at a distance from the housing (3) of the turbine. The sensor (5) detects the pulsating pressure fluctuations in the return line (4) and feeds these to an amplifying and evaluating electronic module (11). No problem arises with regard to confined spatial relationships in the turbine housing (3), especially in dental turbines, due to the fact that the sensor (5) is arranged at a distance from the turbine housing (3) and not in the same. In addition, the sensor (5) is not a...
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FOLDABLE CARRIER FOR RETAINING OBJECTS

(WO1999058425) 18.11.1999 B65D 73/00 TOUSSAINT, Stephen, M.
A carrier (10) for securely retaining one or more objects is provided, cut and scored from a unitary blank of paperboard or similar foldable sheet material so that it can be folded into two overlying panels (16, 18) and then manually fastened so that one panel is characteristically bowed away from the other to form an interior space. This bowed panel has at least one unshaped mouth opening (79) into this interior space, cut through the bowed panel face and large enough to allow an object to be loosely inserted through it with one-hand and retained therein for storage or transport. Also, the carrier can be attached to the surface of selected articles with an adhesive strip (60) applied to the back of the carrier or by using a standard pronge...
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A METHOD AND A SYSTEM FOR FILLING GOODS IN BAGS FROM A COHERENT SERIES OF BAG MEMBERS

(WO1999057017) 11.11.1999 B65B 43/12 SCHUR PACKAGING SYSTEMS A/S
In connection with the packaging of items or loose material in sheet packings it is known to use a web of cohering flat bag members, which is successively conveyed to a filling station, in which the bag members are opened, one by one, for filling and subsequent closing and separation from the web. The free mouth edges of the bag members or the web are profiled for supported conveyance on opposed carrier rods, tubes or gripping chains which, just before the filling station, diverge from each other for effecting opening of the bag members. The invention provides for a flat bag web, the upright edge strip portions of which are caused to be folded down over respective opposed carrier chains. These strip portions are prepared with a row of perfo...
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METHOD FOR SANITIZING DENTAL EQUIPMENT USING MICROWAVES

(WO1999056794) 11.11.1999 A61L 2/12 THE PROCTER &GAMBLE COMPANY
A method by which dental equipment, such as dental scalers, can be sanitized using a detergent or treating composition containing a surfactant and a solvent such as water is disclosed. The method involves taking the used dental equipment and contacting it with the treating composition, and subjecting both the equipment and composition to microwaves. The composition foams during microwaving and/or immerses the equipment such that microwave arcing is avoided, and such that the dental equipment is sanitized.
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GUTTER SYSTEM

(WO1999053157) 21.10.1999 E04D 13/064 PRESTON, John, Clement
A gutter comprising a trough adapted to be secured below a roof and to receive rainwater run-off therefrom. The trough having a mouth disposed between a front edge and a rear edge thereof, and a perforated cover sheet extends over the mouth. The cover sheet and said trough are formed from a single strip of sheet material.
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METHOD AND HIGH-CAPACITY APPARATUS FOR PRODUCING FIRE FIGHTING FOAM AND FOAM EXPANDING SPREADING DEVICE

(WO1999052599) 21.10.1999 A62C 5/02 SZO^'CS, Istvn
Method for producing fire fighting foam using a composition is prepared consisting of foaming agent, water and gaseous medium. The composition is prepared via dissolving or emulsifying the components in one another under overpressure, the composition prepared this way is stored under overpressure at the required place for the required period of time, transported if necessary maintaining the overpressure, and it is expanded via decompressing it on the spot and at the time of application. The apparatus for producing the fire fighting foam comprises a high-pressure foam source (10), a foam expanding spreading device (60) and a pressure resistant pipeline (40) connecting the high-pressure foam source (10) with the foam expanding spreading devic...
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METHOD FOR THE THERAPEUTIC AND PROPHYLACTIC TREATMENT OF DENTAL DISEASES

(WO1999052596) 21.10.1999 A61C 5/00 ALTSHULER, Grigory Borisovitch
The present invention relates to a method for the therapeutic and prophylactic treatment of dental diseases, wherein said method comprises illuminating the oral cavity using an optical radiation and cleaning the teeth during the emission of said radiation. The various illumination and cleaning modes proposed in this invention provide respectively for the therapeutic and prophylactic treatment of caries, periodontium and inflammations.
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CONJUGATE VACCINES FOR THE PREVENTION OF DENTAL CARIES

(WO1999052548) 21.10.1999 C07K 14/315 LEES, Andrew
The present invention provides glucan-based compositions and methods for stimulating an immune response against mutans streptococci components and vaccines and methods for the treatment and prevention of dental caries. In a preferred embodiment, a glucan polymer is covalently bound to one or more T cell-dependent antigens to form a conjugate vaccine. The T cell-dependent antigen preferably contains epitopes of one or more mutans streptococcal proteins, such as a glucosyltransferase. Moreover, one or more moieties, including haptens, may be conjugated to the glucan or to the glucan-T cell-dependent composition. In a preferred embodiment, these moieties are peptides which contain immunogenic epitopes corresponding to components of a mutants s...
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DEVICE FOR CLEANING THE FILTERING ELEMENTS OF AN INDUSTRIAL AIR FILTER

(WO1999051321) 14.10.1999 B01D 46/04 MORO FRANCO, Eusebio
Device which is intended to be installed in registration with the outlet mouth of the filtering elements which comprise a cage covered by a porous sleeve to retain the particles suspended in the duty air to be filtered. The device can be fixed at the proximity of the outlet mouth of the filtering element and compressed air is injected towards the inside of each filtering element in order to clean the porous sleeve and remove all particles which are adhered thereto same during the filtering operation. To this effect, the device comprises a telescopic nozzle (1) fixed to the outlet mouth (4) of the filtering element (5) by means of arms (3) so that in the active position of the nozzle the last section of said nozzle through which air comes ou...
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ORGANIC COMPOSITE FILLER, PROCESS FOR PRODUCING THE SAME, AND DENTAL POLYMERIZABLE FILLER COMPOSITION CONTAINING THE SAME

(WO1999051190) 14.10.1999 A61K 6/083 SUN MEDICAL CO., LTD.
A dental polymerizable filler composition which is excellent in mechanical strength, especially flexural strength, is satisfactory in wearing resistance and water resistance, and gives a cured material having excellent flexural strength. The composition comprises an organic polymerizable monomer (E), a polymerization initiator, and an organic composite filler. The filler comprises a powder of a cured material obtained by polymerizing a mixture of (A) an isocyanurate having an ethylenically unsaturated group, (B) a (meth)acrylate monomer having a functionality of 2 or higher, (C) an inorganic filler, and (D) a polymerization initiator.
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ADHESIVE FOR DENTAL PROSTHESES

(WO1999051189) 14.10.1999 A61K 6/00 SCHMIDT, Joachim
The invention relates to an adhesive for dental prostheses, consisting mainly of pectins or pectinates. Said adhesive is a pectin or pectinate which contains mainly acetyl groups and does not gel and/or a pectin or pectinate which contains low-esterified acid amides and gels on reaction with calcium.
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ORAL ANTIMICROBIAL AND ANTI-ODOR COMPOSITIONS

(WO1999051093) 14.10.1999 A01N 31/00 INNOSCENT LTD.
The invention is directed to the use of a composition comprising a higher alcohol selected from 1-nonanol, 1-decanol and 1-undecanol, or mixtures thereof and taste-masking additives, as an oral anti-odor preparation. The invention further provides anti-odor toothpaste, mouthwash, candies and other anti-odor preparations for oral use.
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TOOTH WHITENING COMPOSITION

(WO1999048467) 30.09.1999 A61K 8/21 BIOCOSMETICS, S.L.
The composition contains carbamide peroxide (0.3-60 %), xylitol (0.5-50 %) potassic salt (0.001-10 %) and fluorine salt (0.15-3 %). There is also disclosed a gel which contains, in addition to the whitening composition, between 0.5 and 6 % by weight of an appropriate gelifying agent. The gel is appropriate to the whitening of dental pieces through a treatment which comprises applying an efficient amount of said whitening gel onto the dental pieces to be whitened. The composition may also be presented in the form of a dental paste, mouth wash or elixir.
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TEETHING GEL APPLICATOR

(WO1999048460) 30.09.1999 A61J 17/02 BADALAMENTI, Michael, J.
This invention is a teething gel applicator (10) including a teething ring (14). The teething ring (14) has a chewing portion (28) sized to be partially inserted into a child's mouth. The teething ring (14) has a series of depressions (30) for holding a gel. A handle (24), sized to be grasped by a child, is connected to the chewing portion (28). A gel spreader (20), that is removably secured to the chewing portion (28), is used to fill the depressions (30) with the gel. The gel spreader (20) receives a vial (22) containing the gel, and rotates around the chewing portion (28) to deposit the gel in the depressions (30).
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REMINERALIZATION OF TEETH

(WO1999047108) 23.09.1999 A61K 8/24 UNILEVER N.V.
An oral product and method is provided for remineralizing teeth. The product includes a first composition containing a water soluble calcium phosphate salt or monolithic combination of calcium and phosphate salts in a carrier with the first composition having a pH less than 7, and a second composition containing an alkaline material and a fluoride ion source in a carrier to achieve a pH greater than 7.5. The first and second compositions are separated from one another prior to use. When combined upon application to teeth, the first and second compositions generate hydroxyapatite depositing same on dental enamel.
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BIS-BIGUANIDE ANTIPLAQUE DENTIFRICE EXHIBITING REDUCED STAINING

(WO1999045898) 16.09.1999 A61K 8/43 COLGATE-PALMOLIVE COMPANY
A dual component chlorhexidine dentifrice composition in which the first component contains a bis-biguanide antibacterial agent and the second component contains an abrasive incompatible with the bis-biguanide, wherein maximum antibacterial effect on dental tissue with reduced staining is achieved when the components are physically separated prior to use and are mixed upon application to dental issue.
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DENTAL RESTORATIONS

(WO1999045889) 16.09.1999 A61K 6/06 JENERIC/PENTRON INCORPORATED
A dental restoration comprising a porcelain composition, comprising a glassy matrix and leucite crystallites embedded therein, and having maturing temperatures in the range from about 680 C to about 870 C and CTEs in the range from about 12 to about 15, more preferably in the range from about 12.5 to about 14.5 and most preferably in the range from about 13.1 to about 14.5 x 10?-6/C (measured from 25 C to 470 C). The porcelain is used in combination with a ceramic core or metal framework. The ceramic core comprises cubic leucite and exhibits maturing temperatures less than about 1200 C and CTEs in the range of about 12.5 to about 15.0 x 10?-6/C (measured from 25 C to 500 C).
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LOW FUSING DENTAL PORCELAINS CONTAINING FINE-GRAINED LEUCITE

(WO1999045888) 16.09.1999 A61K 6/06 JENERIC PENTRON INCORPORATED
A dental porcelain composition, comprising a glassy matrix and leucite crystallites embedded therein, and having maturing temperatures in the range from about 600 C to about 885 C and CTEs in the range from about 11 to about 19, more preferably in the range from about 11.5 to about 18, and most preferably in the range from about 12 to about 17.5 x 10?-6/C (measured from 25 C to 500 C). The tetragonal leucite is preferably both fine-grained (i.e., having average diameters of less than about 7 microns) and uniformly-sized. Preferably, the average diameters are less than about 1 to about 3 microns.
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LIQUID MECHANICAL PUMP

(WO1999045275) 10.09.1999 F04C 29/06 SIEMENS AKTIENGESELLSCHAFT
The invention relates to a liquid mechanical pump, comprising a rotatably mounted running wheel in a pump housing, at least one control disk with an aspirating port and a pressure port. The pressure port opens into a pressure chamber via the control disk and the pump cover. A pressure pipe is connected to the pressure chamber. A closing member is arranged inside the pressure chamber in the path of flow between the opening of the pressure port and the opening of the mouth of the pressure pipe. Said closing member has a through opening which includes a cross-section that can automatically be adapted to the volume of the medium transported by the inventive pump. The invention is characterised in that the closing member is a moveable plate secu...
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TOOTHPASTE AND MOUTH RINSE COMPOSITIONS

(WO1999044574) 10.09.1999 A61K 8/58 LIFE PLUS INTERNATIONAL
A composition for oral administration as a toothpaste or mouth rinse has an effective amount of one or more plant extracted polyphenols and/or an effective amount of oligomeric proanthocyanidin. The composition provides anticaries and antigingivitis benefits without necessitating the use of fluoride, and with increased stability.
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COMPOSITION AND MEANS FOR TREATING DRY MOUTH

(WO1999044573) 10.09.1999 A61K 8/73 POZUELO, Jose
A tablet is disclosed for increasing the production of saliva in the human mouth. More specifically, a composition is described comprising a combination of organic compounds, insoluble in alkaline medium, combined with a retaining agent. The retaining agent is capable of absorbing and releasing saliva in aqueous solution such that when the compound is held in the oral cavity it remedies the condition of dry mouth.
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NON-STRINGY GEL TOOTHPASTE COMPRISING KAPPA CARRAGEENAN AND CELLULOSE AS BINDERS

(WO1999044572) 10.09.1999 A61K 8/73 FMC CORPORATION
Described herein is a toothpaste composition which comprises an orally acceptable vehicle, a polishing agent, a surface active agent and a binder, the binder containing kappa carrageenan and a cellulose gum, the percent by weight concentration of binder being in the range of about 0.30 to 0.80 %, and the ratio of kappa carrageenan to cellulose gum being in the range of about 25:75 to 75:25. A preferred concentration of binder is in the range of about 0.45 to 0.65 % and a preferred ratio of kappa carrageenan to cellulose gum is in the range of about 55:45 to 75:25. The toothpaste is surprisingly non-stringy, exhibits good consistency, transparency and physical stability.
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HIGH MOISTURE TOOTHPASTE

(WO1999044571) 10.09.1999 A61K 8/19 FMC CORPORATION
A stable, high moisture toothpaste has now been developed that comprises a carrageenan binder that is at least 70 % iota carrageenan, a calcium based-polish agent, humectant, surfactant, water and optional additives and therapeutic actives used in dentifrice compositions. The calcium-based agent is present at a weight percent concentration in the range of about 35 to 50, the water is about 35 to 50 %, the humectant is about 5 to 15 %, the carrageenan is about 0.5 to 0.85 %, and the surfactant is about 0.5 to 5 %. The high moisture, low cost toothpaste that is provided has favorable physical properties such as good viscosity and stability without the need for additional binder which is optional.
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DESENSITIZING DENTAL COMPOSITION

(WO1999044570) 10.09.1999 A61K 6/00 ITALMED S.N.C. DI GALLI G. E PACINI G.
A dental composition for the treatment of dentinal hypersensitivity and in particular for the desensitization of exposed dentin, the desensitizing treatment of deep cavities, the desensitizing treatment when replacing dental layers, the stumps desensitizing treatment before placing dental prosthesis. The composition can be used as a solution or as a gel. In the first case two distinct liquid solutions for use successively on the exposed dentin are provided for. In the second case two distinct gel compounds spread successively on the exposed dentin are provided for. The first solution or the first gel compound comprises preferably three soluble potassium salts, whereas the second solution or the second gel compound comprises a calcium salt a...
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FILAMENT TAPE FOR CLEANING AND DENTAL APPLICATION

(WO1999044466) 10.09.1999 A46B 5/06 ZAPANTA, Gary
A cleaning device comprising: a cleaning tape element comprising a plurality of individual filaments (116) such as bristles or fibers, the plurality of individual filaments (116) each having (i) a cleaning tip (122) disposed at a first end (120) of the filament, and (ii) a second end (118) and (iii) means (242) for maintaining the plurality of individual filaments (116) in at least one, single filament-wide row, thereby forming a tape; and a base portion, the plurality of individual filaments (116) coupled to the base portion adjacent their respective base ends (118).
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ORAL CARE COMPOSITIONS COMPRISING CHLORITE

(WO1999043295) 02.09.1999 A61K 33/20 THE PROCTER &GAMBLE COMPANY
The present invention relates to oral care compositions, including therapeutic rinses, especially mouth rinses, as well as toothpastes, gels, tooth powders, chewing gums, mouth sprays, and lozenges (including breath mints), comprising at least a minimally effective amount of chlorite ion, wherein preferably the pH of the final composition is greater than 7 and level of chlorine dioxide or chlorous acid is less than about 50 ppm, preferably is essentially free of chlorine dioxide or chlorous acid. This invention further relates to a method for treating or preventing gingivitus, plaque, periodontal disease, and/or breath malodor, and/or for the whitening of teeth, in humans or other animals, by applying a safe and effective amount of the chlo...
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ORAL CARE COMPOSITIONS COMPRISING CHLORITE AND METHODS

(WO1999043294) 02.09.1999 A61K 33/20 THE PROCTER &GAMBLE COMPANY
The present invention relates to oral care compositions, including therapeutic rinses, especially mouth rinses, as well as toothpastes, gels, tooth powders, chewing gums, mouth sprays, and lozenges (including breath mints), comprising at least a minimally effective amount of chlorite ion, wherein preferably the pH of the final composition is greater than 7 and level of chloride dioxide or chlorous acid is less than about 50 ppm, preferably is essentially free of chlorine dioxide or chlorous acid. This invention further relates to a method for treating or preventing gingivitis, plaque, periodontal disease, and/or breath malodor, and/or for the whitening of teeth, in humans or other animals, by applying a safe and effective amount of the chlo...
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IMPROVED DENTAL ABRASIVE

(WO1999043291) 02.09.1999 A61K 8/25 COLGATE-PALMOLIVE COMPANY
Oral compositions, such as oral gels and toothpastes, containing a novel high cleaning, low abrasion silica hydrogel abrasive.
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ORAL CARE COMPOSITIONS COMPRISING CHLORITE AND METHODS

(WO1999043290) 02.09.1999 A61K 7/16 THE PROCTER &GAMBLE COMPANY
The present invention relates to oral care compositions, including therapeutic rinses, especially mouth rinses, as well as toothpastes, gels, tooth powders, chewing gums, mouth sprays, and lozenges (including breath mints), comprising at least a minimally effective amount of chlorite ion, wherein preferably the pH of the final composition is greater than 7 and level of chlorine dioxide or chlorous acid is less than about 50 ppm, preferably is essentially free of chlorine dioxide or chlorous acid. This invention further relates to a method for treating or preventing gingivitis, plaque, periodontal disease, and/or breath malodor, and/or for the whitening of teeth, in humans or other animals, by applying a safe and effective amount of the chlo...
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COMPOSITION FOR MAKING TEMPORARY CROWNS AND BRIDGES

(WO1999040884) 19.08.1999 A61K 6/083 KERR CORPORATION
The invention describes a dental composition, delivery system and method for making temporary crowns and bridges in which the composition comprises two free-radical polymerizable pastes, one a catalyst paste and the other a base paste, wherein the catalyst paste comprises at least one polymerizable monomer, at least one polymerization initiator which is a peroxide oxidizing agent, at least one first polymerization inhibitor and a filler, and wherein the base paste comprises at least one polymerizable monomer, at leat one polymerization accelerator, at least one second polymerization inhibitor, at least one non-polymerizable plasticizer and a filler. These catalyst and base pastes are stored in a dual cartridge from which they can be dispens...
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LIGHT-ACTIVATED TOOTH WHITENING COMPOSITION AND METHOD OF USING SAME

(WO1999040870) 19.08.1999 A61C 5/00 BRITESMILE, INC.
The present invention provides a tooth whitening composition having a transparent first component that is a carrier compound and a transparent second component that is an oxidizing compound which when applied to a stained tooth and exposed to actinic light is activated to facilitate tooth whitening. The invention also provides a method for light-activated tooth whitening which comprise applying a tooth-whitening composition to one or more teeth and exposing said composition to actinic light to activate said oxidizing compound. The present invention further provides a device for tooth whitening which has a light source, at least one optical output, a projection means for holding and positioning said optical output outside of a patient's mout...
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ANTIMICROBIAL COMPOSITION

(WO1999039711) 12.08.1999 A61K 31/451 SMITHKLINE BEECHAM PLC
A composition comprising loperamide or a pharmaceutically acceptable salt thereof for use in the prevention and/or treatment of microbial infections.
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FALSE TOOTH ATTACHMENT AND METHOD AND SPACER FOR FIXING THE SAME

(WO1999039656) 12.08.1999 A61C 13/235 AICHI STEEL WORKS, LTD.
A false tooth attachment (2) having a high resiliency with respect to a pressing force due to occlusion of teeth and giving a suitable sinking motion to a false tooth at the time of occlusion of teeth, comprising a magnet member (21) adapted to be attracted by a magnetic force to a root cap buried in a dental root, and a cap (22) covering the surface of the magnet member (21) which is on the opposite side of the surface thereof attracted to the root cap, the attachment being buried in a dental plate, the magnet member (21) having in the central portion of a rear surface (21c) thereof a recess (210), in which a projection (223) of the cap (22) of a hard resin is fitted in a contacting state, the projection (223) being elastically deformed an...
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A METHOD AND AN APPARATUS FOR CLEANING AND STERILIZING DENTAL EQUIPMENT

(WO1999038539) 05.08.1999 A61C 19/00 INTER SELECT BY POLTI A/S
The present invention relates to a method of cleaning and sterilizing dental equipment (80), which is intended to be introduced into the oral cavity of a patient, and which has an external surface and an internal channel defined by an internal surface, said method comprising a first step wherein the internal surface is affected by steam at such a temperature that the internal surface is sterilized. The invention is novel by an additional step wherein the external surface is affected by a relatively concentrated jet of steam at such a temperature that the external surface is sterilized, while a mechanical treatment of the external surface is performed by a brush-like means. The invention also relates to an apparatus for performing the method...
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METHODS AND APPARATUS FOR ACTIVATING DENTAL COMPOSITIONS

(WO1999037236) 29.07.1999 A61C 5/00 ULTRADENT PRODUCTS, INC.
Compositions, method and systems for bleaching tooth surfaces in an accelerated manner. The dental bleaching compositions include a bleaching agent and a stable radiant energy absorbing material that acts as a bleaching agent activator. The dental bleaching compositions of the present invention can be stable one-part compositions that do not require mixing at the time of treating a person's teeth but which remain stable over time. The dental bleaching composition is applied to the labial surface of teeth that are to be bleached. A source of radiant energy is directed onto the treated tooth surfaces to accelerate bleaching activity. The radiant energy source includes a dental light guide having an arcuate light directing member that is posit...
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MAXILLOFACIAL ANCHORING SYSTEM FOR ALVEOLAR AND SMALL BONE SKELETAL DISTRACTION

(WO1999037230) 29.07.1999 A61B 17/66 CARCHIDI, Joseph, Edward
A maxillofacial anchoring and distracting system (10) is shown for lengthening the alveolar and small craniofacial skeletal bones by distraction osteogenesis. The distraction system includes a base plug (12), an internally and externally threaded anchoring screw body (14), a distraction jack screw (16) and healing screw (18). The base plug is press-fit into an osteotomy and acts as a baseplate to resist and transfer force received from the distraction jack screw to the subperiosteal corticotomy callus. The application of distraction force to the subperiosteal corticotomy via the distraction jack screw is resisted coronally by the anchoring screw body. Once the desired monofocal distraction osteogenesis has been completed, the maxillofacial ...
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COMPOSITION AND METHOD FOR LUBRICATING AND PROTECTING THE ORAL CAVITY USING FLAVORED PETROLEUM JELLY

(WO1999036031) 22.07.1999 A61K 8/31 MCDANIELS, Pellom, III
A composition and method for lubricating and protecting the oral cavity generally and specifically the teeth, gums and tongue using a flavored petrolatum. In the preferred embodiment, the composition contains about 96 %-98 % (w/w) of petrolatum and about 2 %-4 % (w/w) of flavoring. The compositions is liberally applied to the affected areas of the oral cavity to lubricate and protect those areas during dental or medical procedures having an aesthetically pleasing flavor without leaving an undesirable aftertaste.
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ANTI-FUNGAL COMPOSITIONS WITH PROLONGED ACTIVITY

(WO1999034811) 15.07.1999 A01N 65/00 FARMO-NAT LTD.
An anti-fungal composition, including: (a) an extract of botanical materials, the botanical materials including material from Echinacea species, and Propolis, which is a material derived from the hives of bees; and (b) an essential oil. The compositions of the present invention have been shown to have unexpectedly prolonged anti-fungal activity, as well as having anti-bacterial and anti-inflammatory activities. Preferably, the essential oil includes at least one oil selected from the group consisting of tea-tree oil, thyme oil and lavander oil. Also preferably, the herbal extract includes a mixture of Calendula, poke root, Echinacea and Propolis extract.
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ANTIMICROBIAL PEROXY ACID ORAL CARE COMPOSITIONS AND METHODS

(WO1999034773) 15.07.1999 A61K 7/20 THE PROCTER &GAMBLE COMPANY
The present invention relates to compositions, especially shampoos, roll sticks, gels, rinses, and oral care compositions such as mouth rinses, toothpastes, tooth powders, mouth sprays, chewing gums, lozenges, sachets, and bleaching kits, etc., for the treatment of topically-treatable microbial infections, comprising the reaction mixture of: (1) a safe and effective amount of a peroxy acid compound, or pharmaceutically-acceptable salts or esters thereof; (2) a safe and effective amount of an ion source selected from the group consisting of chloride ion, bromide ion, iodide ion, thiocyanate ion, and mixtures thereof; and (3) a pharmaceutically-acceptable, topical excipient. Furthermore, the present invention also relates to methods for treat...
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DUAL COMPONENT ANTIPLAQUE DENTIFRICE COMPOSITION

(WO1999034769) 15.07.1999 A61K 7/16 COLGATE-PALMOLIVE COMPANY
A dual component antiplaque dentifrice composition in which the first component is an extrudible dentifrice composition containing a nonionic antibacterial agent in which calcium salts are absent and the second component is an extrudable dentifrice composition containing a calcium salt wherein maximum antibacterial agent uptake by dental tissue is achieved when the components and are physically separated prior to use and are mixed upon application to dental tissue.
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PREPARATION FOR DENTAL TREATMENT

(WO1999034765) 15.07.1999 A61K 6/00 MEDITEAM DENTALUTVECKLING I GTEBORG AB
The invention relates to a preparation for use in chemical-mechanical treatment of caries in the form of a two-component caries dissolving liquid in which one of the components consists of sodium hypochlorite and the other component of a substance with the ability to reduce the aggressive influence of sodium hypochlorite on mucous membranes. The other component is a gel component which consists of a gel substance without any amino acids or a gel substance mixed with one or more amino acids.
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MODIFIED ENZYMES COMPRISING A POLYANIONIC DOMAIN

(WO1999033957) 08.07.1999 A61K 8/66 NOVO NORDISK A/S
A modified enzyme comprising an enzyme and at least one polyanionic domain, e.g. polyglutamic acid, polyaspartic acid or a polycarboxylic acid, wherein the enzyme comprises or is covalently attached to each said polyanionic domain. Also disclosed are oral care compositions comprising such modified enzymes and use of the oral care compositions for preventing or treating dental disease, in particular for preventing or removing plaque. The modified enzymes are able to bind to hydroxylapatite in teeth.
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TOOTH CLEANING COMPOSITION IN TABLET FORM

(WO1999033437) 08.07.1999 A61K 7/16 THE PROCTER &GAMBLE COMPANY
A toothpaste tablet is disclosed, comprising: (a) from about 20 to about 80 % of a polishing agent; (b) from about 0.2 to about 5.5 % of a thickening agent; and (c) from about 30 to about 80 % of a tableting carrier.
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POTATO-BASED SNACKS AND METHODS FOR PREPARING THEM

(WO1999033357) 08.07.1999 A23L 1/217 THE PROCTER &GAMBLE COMPANY
The texture and flavor release of fabricated snacks are selectively controlled by incorporating into potato-based dough different ingredients having various properties which allows control of the (1) visco-elastic properties of the dough, (2) amount of expansion that occurs in the dough during frying, (3) rate of water release during frying, (4) internal structure of the finished snack, (5) rate of flavor release from the finished snack and, (6) rate of hydration and dissolution of the finished snack in the mouth. The product is prepared from a dough composition which is primarily composed of (1) mainly one or more potato-based ingredients selected from potato flour, potato flakes, or potato granules and mixtures thereof, together with (2) ...
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A PREPARATION FOR THE TREATMENT OF APHTAE

(WO1999032132) 01.07.1999 A61K 31/015 DENTAL THERAPEUTICS AB
The present invention relates to a preparation for the treatment of aphtae, preferable aphtae stomatitis. The preparation includes: (a) 5.0 - 10.0 % by weight of orange interpenes; (b) 0.1 - 3.0 % by weight of glycyrrhizin; (c) 0.1 - 1.5 % by weight of xylitol; (d) 1.0 - 10.0 % by weight of cocoamphodiacetate. The inventive preparation is administered in the form of mouthwash, paste, tablets, capsules or chewing gum.
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DARK-BOX FOR STORING LIGHT-SENSITIVE STORAGE LAYER RADIATION SCREENS

(WO1999028209) 10.06.1999 G03C 3/00 DENTSPLY INTERNATIONAL
A container is provided for the storing of light sensitive exposed storage layer radiation screens. The container includes walls defining an interior volume, an aperture in one of the walls sized to allow entry of a storage layer radiation screen, a screen receiving surface adjacent to the aperture which is shaped to direct a dropped screen into and through the aperture into the interior volume, an interior dark section of the container within which light exterior to the container cannot reach, and an interior guiding section that is shaped to direct a screen dropped through the aperture to come to rest in the interior dark section. A method is provided for storing light sensitive exposed storage layer radiation screens. The method includes...
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COLOR INDICATOR FOR DENTAL IMPRESSION MATERIAL

(WO1999027895) 10.06.1999 A61K 6/10 COLGATE-PALMOLIVE COMPANY
The invention relates to a dental impression composition and method of use thereof for taking impressions of the teeth amd gums and/or for the delivery of actives thereto; containing a color change indicator to signal when the temperature of the dental impression material is at the 'warm impression' state, so that the impression composition is soft and malleable to conform to and engulf the teeth and gums. Further, the color indicator subsequently signals when the dental impression composition has cooled to a solid state and can be removed from the dentiture without deforming, so as to maintain an accurate impression.
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AN ANTIMICROBIAL COMPOSITION

(WO1999027793) 10.06.1999 A01N 65/00 BARRIER BIOTECH LIMITED
There is disclosed an antimicrobial composition comprising an antimicrobially effective amount of clove bud oil and two or more of eucalyptus oil, cajaput oil, lemongrass, lavender or tea tree oils. Use of the composition as a treatment for cold sores, head lice, vaginal thrush, verruca, warts, athletes foot, an antimicrobial mouth wash in addition to a surface cleaner are also disclosed.
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MUCOSAL DELIVERY SYSTEM COMPRISING LIPOPHILIC THROMBIN INHIBITORS

(WO1999026652) 03.06.1999 A61K 9/48 WEST PHARMACEUTICAL SERVICES DRUG DELIVERY &CLINICAL RESEARCH CENTRE LIMITED
A composition for the delivery across a mucosal surface of a lipophilic thrombin inhibitor comprising a lipophilic thrombin inhibitor and a non-ionic surfactant. Preferably, the mucosal surface is in the gastrointestinal tract, nose, mouth, rectum or vagina. Advantageously, the thrombin inhibitor is a peptide boronic acid or ester derivative thereof. Conveniently, the non-ionic surfactant is an ethoxylated glyceride. Suitably, the composition is contained within a capsule. In addition, the invention also relates to methods of making said compositions and the use of said compositions in medicine.
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WHITENING, ANTIPLAQUE AND ANTITARTAR LOW ABRASIVITY TOOTH PASTE

(WO1999025315) 27.05.1999 A61K 8/24 BIOCOSMETICS, S.L.
The improvements relate to the formulation of a whitening, antiplaque, antitartar, low abrasivity tooth paste which is appropriate for the treatment of dental hypersensitivity, free of detergents and comprises 0.1-1 % of papaine, 5-10 % of xilitol, 16-18 % of a silica-based abrasive system, a buffer comprised of tetrapotassic pyrophosphate and potassic dihydrogenophosphate (pH 7 approximately), as well as water, agglutinates, flavouring agents, colorants, preservatives, sweeteners, moisturing agents, lubricants, opacifiers, remineralisers and vitamines A, B5, C, E or mixtures thereof.
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DENTAL FLOSS

(WO1999025269) 27.05.1999 A61C 15/04 JOHNSON &JOHNSON INDSTRIA E COMRCIO LTDA.
Dental floss, of the type comprising a strand consisting of multiple filaments, which are made from one or more materials selected from the group consisting of cotton, silk and polymeric materials, and a coating composition which impregnates said strand and includes a water emulsionable carrier carrying one or more active agents selected from the group consisting of germicides, therapeutic agents, flavorants, sweeteners, abrasives and others, at least one sweetener being in aqueous solution. According to the invention, the water emulsionable carrier includes a waxy material selected from the group consisting of animal waxes, mineral waxes, vegetable waxes, synthetic waxes and mixtures of two or more of these waxes and an emulsifier, in orde...
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POLYMERIZABLE COMPOSITION AND THE APPLICATION THEREOF AS A COUPLING AGENT

(WO1999024477) 20.05.1999 A61K 6/00 ESPE DENTAL AG
The invention relates to a polymerizable, cross-linkable composition which contains: (A) 1 - 99.99 wt. % of at least one conversion product of OH-functional (meth)acrylates with (i) oligomers from unsaturated rings or heterocyclic rings and maleic anhydride and/or with (ii) at least one ring-shaped polycarboxylic acid with at least 4 ring-carbon atoms and/or the anhydrides thereof with a saturated ring system, at least 4 carboxyl groups, and 0 or 1 heterocyclic ring atoms from the group N, O, S, whereby at least one carboxyl group and/or anhydride group of the above described substance groups is reacted with unsaturated polymerizable groups; (B) 0 to 98.99 wt. % of one or more polymerizable, unsaturated organic compounds with at least one C...
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AUTOMATIC PNEUMATIC PROJECTILE LAUNCHER

(WO1999024179) 20.05.1999 B08B 9/04 COMPRI TECHNIC PTY. LTD.
An automatic pneumatic projectile launcher (10) for automatically launching compressible cleaning projectiles (22) into a hose, pipe or tube is disclosed. The launcher (10) comprises a moveable hopper (12) having an opening (14) provided at a lower end thereof coupled to a feed tube (16). The hopper (12) is moved up and down vertically in a reciprocating motion by four double acting pneumatic rams (25), located adjacent each corner of the hopper (12). The feed tube (16) acts as a magazine for the projectiles (22), is stationary and is slidably received through the hopper base plate (18) so that it projects upwards into the hopper during a downward stroke. The shape of the feed tube (16) is selected so that projectiles (22) enter the mouth o...
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VISCOUS COMPOSITIONS CONTAINING CARBON DIOXIDE

(WO1999024043) 20.05.1999 A61K 8/19 MEDION RESEARCH LABORATORIES INC.
Viscous compositions containing carbon dioxide wherein carbon dioxide bubbles are held in a water-containing viscous composition. Use of these compositions makes it possible to treat or ameliorate itching accompanying mucocutaneous diseases or mucocutaneous disorders, mucocutaneous injury, dental diseases, skin ulcer, cold flush and numbness caused by peripheral circulatory disorders, musculoskeletal diseases, nervous system diseases, keratosis, constipation, unwanted hair growing after depilation, cosmetic troubles in the skin or hair, partial obesity, etc. while exerting little side effects.
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ORAL CLEANSING: METHODS AND COMPOSITIONS

(WO1999024005) 20.05.1999 A61K 8/365 CHAYKIN, Sterling
The invention relates to edible oral cleansing and sanitizing compositions and the use of these compositions for reducing plaque and calculus deposition in the mouth and improving oral cleanliness and tooth smoothness. The active ingredients include surfactants, sequestrants, and protein precipitants, each present in a specified concentration range. In a preferred embodiment, the hard candies comprise between about 0.01 % and 20 % surfactant, especially a glyceride or alkyl sulfate, 0.01 and 10 % sequestrant, especially citric acid, and 0.01 % and 10 % protein precipitant, especially tannic acid.
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COMPOSITIONS AND METHODS FOR REDUCING THE QUANTITY BUT NOT THE CONCENTRATION OF ACTIVE INGREDIENTS DELIVERED BY A DENTIFRICE

(WO1999022704) 14.05.1999 A61K 7/16 ULTRADENT PRODUCTS, INC.
Toothpaste and other dentifrices formulated to include a volume increasing agent (density reducing agent) in order to significantly increase the volume of the toothpaste at the time it is dispensed onto a toothbrush. The inventive dental compositions preferably include a substantial quantity of entrained air or other gas in order to reduce the density, and hence the weight, of toothpaste actually placed within a person's mouth. The result is a reduction in the amount of active ingredients introduced into a person's mouth that might be ingested. The entrained air or other gas can also increase the availability of the active ingredient since the foamed composition increases the dispersibility of the active ingredients within saliva. The net e...
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PLAQUE-INHIBITING ORAL COMPOSITIONS

(WO1999020239) 29.04.1999 A61K 8/66 NOVO NORDISK A/S
The present invention relates to oral compositions comprising plaque-inhibiting or plaque-removing enzymes, in particular at least one starch-hydrolysing enzyme, e.g. an $g(a)-amylase or a debranching enzyme such as a pullulanase, and/or at least one starch-modifying enzyme, e.g. a transglucosidase or a CGTase, and to a method for inhibiting plaque formation or removing plaque using such oral compositions.
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STOMATIC COMPOSITION

(WO1999020237) 29.04.1999 A61K 33/42 ZAKRYTOE AKTSIONERNOE OBSCHESTVO OSTIM
This invention relates to the field of medicine, and in particular to the stomatology and may be used for preventive treatment and combatting caries, parodenitis and paradentosis. The stomatic composition on the basis of hydroxyapatite also comprises abrasive materials, humectants, thickeners, surfactants, flavouring agents, and a number of optional ingredients. The composition comprises hydroxyapatite in the form of particles of ultra finely divided hydroxyapatite with an average size by length (1), width (d) and thickness (h) of about 1 x d x h = 0,06 $g(m)m x 0,015 $g(m)m; x 0,005 $g(m)m is capable to stimulate reparative osteogenesis processes and possessing a high bioactivity and specific pharmacological activity. The ultra finely divi...
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DISINFECTING AGENT

(WO1999020228) 29.04.1999 A01N 47/44 DDG DENTAL DEVICES GMBH
The invention relates to a disinfecting agent composition containing chlorphenyl- and/or chlorbenzyl-biguanide-compounds and benzoic acid or the salts thereof in an aqueous alcoholic solution. The invention also relates to the application of the disinfecting agent in the dental field.
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TWO-COMPONENT DENTAL BLEACHING SYSTEM AND METHOD

(WO1999020226) 29.04.1999 A61K 6/00 PELLICO, Michael, A.
A two-component dental bleaching system is provided wherein the components are adapted to be admixed and applied to the teeth from a dental bleaching tray. One component comprises a dental peroxide gel having a pH from about 4 to about 7 and the other component comprises an orally compatible alkaline gel having a pH from about 9 to about 13. The admixing of the components provides a dental bleaching gel having a pH from about 8,5 to about 11 to thereby increase the rate of release of active oxygen and accelerate the bleaching action.
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DENTAL COMPOSITES COMPRISING GROUND, DENSIFIED, EMBRITTLED GLASS FIBER FILLER

(WO1999020225) 29.04.1999 A61K 6/083 JENERIC/PENTRON INCORPORATED
A composite for a dental restoration is presented comprising ground, densified, embrittled glass fibers together with fillers and a polymeric matrix precursor composition. The ground, densified, embrittled glass fibers are obtained by grinding glass fibers which have been densified and embrittled by heating glass fibers at a temperature substantially below the softening point of the glass fibers, without significant fusion or melting together of the fibers. The composite is particularly useful as a direct filling material, in that it has the feel and workability of an amalgam.
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METHOD AND CASTING NOZZLE FOR CASTING-ON A METAL STRIP WHICH IS CLOSE TO FINAL DIMENSIONS

(WO1999019098) 22.04.1999 B22D 11/06 SMS DEMAG AG
The invention relates to a method and a casting nozzle for casting-on a metal strip which is close to final dimensions. According to said method, the melt, especially steel, is guided via a melt feed vessel in a pour-in chamber of a skimmer-type vessel and then from said pour-in chamber via a main chamber which is subjected to negative pressure, and finally onto a cooled transportation belt by means of a casting nozzle. The invention is characterised by the following steps: a) the pour-in chamber and the main chamber are filled to the top of the skimmer; b) the negative pressure device connected to the main chamber is activated before the melt flows over the skimmer top; c) after the melt has flowed over the skimmer top, the melt flow is gu...
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LIGAND BINDING SITE OF RAGE AND USES THEREOF

(WO1999018987) 22.04.1999 A61K 38/00 THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
The present method provides for an isolated peptide having an amino acid sequence corresponding to the amino acid sequence of a V-domain of a receptor for advanced glycation end product (RAGE). The present invention also provides for an isolated peptide having an amino acid sequence A-Q-N-I-T-A-R-I-G-E-P-L-V-L-K-C-K-G-A-P-K-K-P-P-Q-R-L-E-W-K (Seq. ID No. 1). The present invention provides for a pharmaceutical composition comprising a therapeutically effect amount of an isolated peptide having an amino acid sequence corresponding to the amino acid sequence of a V-domain of RAGE. The present invention also provides for a method for inhibiting interaction of an amyloid-$g(b) peptide with a receptor for advanced glycation end product which is o...
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LOW FUSING DENTAL PORCELAINS CONTAINING TETRAGONAL RUBIDIUM LEUCITE

(WO1999018912) 22.04.1999 A61K 6/06 JENERIC PENTRON INCORPORATED
A dental porcelain composition, comprising a glassy matrix and rubidium leucite crystallites embedded therein, and having maturing temperatures in the range from about 650 C to about 800 C and CTEs in the range from about 13 to about 17, more preferably in the range from about 13.5 to about 16, and most preferably in the range from about 14 to about 16 x 10?-6/ C (measured from 25 C to 400 C). The tetragonal rubidium leucite is preferably both fine-grained (i.e., having average diameters of less than about 5 microns) and uniformly sized. Preferably, the average diameters are less than about 1 to about 2 microns.
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CUBIC LEUCITE-CONTAINING DENTAL PORCELAINS

(WO1999018910) 22.04.1999 A61K 6/06 JENERIC PENTRON INCORPORATED
A dental porcelain composition comprising a continuous glassy phase and a discontinuous, substantially uniform crystalline phase comprising cubic leucite. The porcelain exhibits coefficients of thermal expansion in the range of about 11 to about 17 x 10?-6/C (measured from 25 C to 500 C) and fusion temperatures in the range of about 700 C to about 1200 C. The porcelain composition of the present invention can be used to form dental restorations such as cores for all ceramic restorations. The cubic leucite phase is uniformly dispersed in the glass matrix and has an average grain size not exceeding about 4 $g(m)m and about 95 % of the leucite grains do not exceed about 8 $g(m)m in diameter.
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DENTAL FLOSSING DEVICE

(WO1999018883) 22.04.1999 A61C 15/04 ROBINSON, Dane, Q.
This invention is an apparatus (10) for cleaning the surface of teeth in a human mouth having a flexible, resilient central flossing filament (34), and a plurality of flexible side flossing filaments (42) fixedly attached to a central filament intermediate portion (40). The central filament intermediate (40), and free end portions with the side flossing filaments (42) attached thereto are sized to be received between adjacent teeth without traversing any contact areas between the adjacent teeth from at least the front of the mouth. The central filament (34) has sufficient flexibility, and the resiliency to effect a first flossing action between the adjacent teeth by imparting a first flossing motion to the central filament. The side filamen...
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COMPOSITION OF TREATMENT OF CANDIDIASIS

(WO1999017788) 15.04.1999 A61K 35/74 ABBOTT LABORATORIES
The present invention provides a method for preventing or treating candidiasis, said method comprising the enteral administration to an animal in need of therapy, an effective amount of at least one probiotic selected from $i(Lactobacillus reuteri, Bifidobacterium infantis, Bifidobacterium lactis), nonviable $i(Lactobacillus acidophilus) and nonviable $i(Lactobacillus casei). Additional aspects of this invention relate to a method for 1) increasing the immune response in an animal to an antigen; 2) reducing the duration and severity of $i(Candida) infections of the skin, mouth, gastrointestinal tract and urogenital tract; and 3) inhibiting $i(Candida) adhesion, colonization and dissemination from the gastrointestinal tract of an animal. All...
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MOUTH HYGIENIC COMPOSITION FOR THE TREATMENT OF HALITOSIS

(WO1999017735) 15.04.1999 A61K 8/44 PEDERSEN, Ejvind, Jersie
A mouth hygienic composition effective in treating halitosis. The composition comprises a chelate comprising a metal ion, preferably a zinc ion, and an amino acid, preferably glycine.
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NICOTINE COMPOSITIONS AND METHODS OF FORMULATION THEREOF

(WO1999015171) 01.04.1999 A61K 9/00 PHARMACIA &UPJOHN AB
Polar lipid formulations of nicotine in liquid crystals and colloidal dispersions thereof and precursors or offspring thereof which when in contact with body fluid and/or by the influence of body temperature, are transformed to a liquid crystal or a mixture of liquid crystals, which functions as a controlled release matrix for nicotine suitable in e.g. smoking cessation and/or replacement therapies. Disclosed compositions of said liquid crystals or dispersions thereof, their precursors or offspring containing nicotine and anti-irritants or a local analgesic, or any combination of these reduce local irritation of nicotine and masks its taste. Applicable routes of administration and devices includes buccal, using chewing gum in which liquid c...
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METHODS AND COMPOSITIONS FOR WHITENING TEETH

(WO1999013852) 25.03.1999 A61K 8/22 UNIVERSITY OF MARYLAND, BALTIMORE
Methods for whitening teeth including contacting teeth with an effective amount of particulate bioactive glass are disclosed.
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CLEANING AGENT FOR DENTAL USE COMPRISING A COMBINATION OF POLISHING AGENTS BASED ON A SILICIC ACID AND ALUMINIUM OXIDE

(WO1999013851) 25.03.1999 A61K 8/24 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
The invention concerns a cleaning agent for dental use in the form of a pasty or liquid dispersion, containing between 10 and 30 wt. % of a combination of polishing agents comprising polishing agents based on silicic acid and aluminium oxide in a weight ratio of 10 : (0.2 - 2) and between 20 and 50 wt. % of a moistening agent from the group containing sorbitol, glycerin, propyleneglycol-1,2, polyethyleneglycol and their mixtures, comprising, for reinforcing the cleaning effect, between 2 and 12 wt. % of condensed phosphate from the group comprising tripolyphosphate, pyrophosphate or trimetaphosphate in the form of alkaline salt or ammonium salt. In spite of their low abrasive values, said cleaning agents have an excellent polishing effect a...
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TUBULAR PLANT GUARD WITH RELEASABLE RETAINING ELEMENT

(WO1999013704) 25.03.1999 A01G 13/10 GRO-GUARD AUSTRALIA PTY. LTD.
Plant guard (10) is formed from a sheet-like panel (11) of flexible material which is folded into a tubular shape with fastener strips on opposite edges of the panel overlapping. Retainer (20) has a channel-shaped recess (30) which receives enlarged head portions on the fastener strips to retain the panel (11) in its tubular shape. The mouth of the channel-shaped recess (30) may be opened to insert or remove the head portions by flexing rear wings (25) of the retainer (20) together to cause forwardly extending limbs (24) defining the recess (30) to move apart. Plant guard (10) may be assembled and disassembled simply and quickly, and retainer (20) encloses the fastening strips to preven