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US PATENT APPLICATIONS IN ORAL CARE FORMULATION PUBLISHED IN 2009



Application No.: US20090001030A1  Published: 01/Jan/2009

Title: Method and Apparatus for Collecting and/or Separating Solids from Liquids

Applicant/Assignee: ULTRA AQUATIC TECHNOLOGY PTY LTD

Application No.: 10/572822   Filing Date: 21/Sep/2004

Abstract:

Apparatus (10) for collecting solids selling on the bottom of a liquid reservoir and/or floating solids, the apparatus (10) having a hollow suction head (23) and at least one outlet duct (26) extending from the suction head (23). Air can be supplied to the suction head (23) to create a suction pressure in the suction head (23) to cause settling solids beneath the suction head (23) to pass along the outlet duct or ducts (26). The suction head (23) may be connected to a collector (11) which is provided with a float (21) to support the collector (11) at the surface of the liquid, and the outlet duct or ducts (26) are connected to the collector (11) which collects the solids. The collector (11) may also have an inlet to collect floating solids.

Priority: AU20030905127 Applic. Date: 2003-09-22; WO2004AU01282 Applic. Date: 2004-09-21

Inventor: NIELSEN IAN BRADLEY [AU]


Application No.: US20090004122A1  Published: 01/Jan/2009

Title: SKIN AND SURFACE DISINFECTANT COMPOSITIONS CONTAINING BOTANICALS

Applicant/Assignee:

Application No.: 12/134918   Filing Date: 06/Jun/2008

Abstract:

The present invention relates to a skin or surface disinfectant composition with broad spectrum antimicrobial activity comprising one or more essential oil (and/or one or more component thereof) and one or more fruit acid. The compositions of the invention may be used as non-toxic alternatives to conventional disinfectants or may be added to other antimicrobial agents to enhance their activity. The invention provides effective alternatives to harsher products which may be particularly useful in personal care and household products and where children and/or pet exposure may be a concern.

Priority: US2008-016788 Applic. Date: 2008-01-18; US20070953654P Applic. Date: 2007-08-02; US20070945288P Applic. Date: 2007-06-20

Inventor: MODAK SHANTA M [US]; BAIJU NAYANA [US]; CARAOS LAUSERPINA A [US]


Application No.: US20090004301A1  Published: 01/Jan/2009

Title: Method of treating dyshidrosis(pompholyx) and related dry skin disorders

Applicant/Assignee:

Application No.: 12/008719   Filing Date: 11/Jan/2008

Abstract:

This invention discloses a method of use for a topical herbal formulation alone or in combination with oral administration of niacin (preferably a flush preparation) to prevent and/or treat dyshidrosis (pompholyx) and related skin diseases. The formulation may also be used to treat contact dermatitis, eczema, palmoplantar pustulosis and skin infections incurred by invasive pathogens such as mold, fungus and bacteria. The formulation is comprised of plant extracts and niacin, that when combined yield an effective multi-faceted pharmaceutical approach to treating dry skin disorders.

The active ingredients within the formula include a combination of dry, aqueous, acid and alcohol extracts of black walnut hull (Juglans nigra), wormwood (Artemisia absinthium), tumeric rhizome (Curcuma longa), garlic (Allium sativum), two or more herbal antibacterial agents from the group consisting of chamomile (Matricaria Chamomile), licorice root (Glycyrrhiza glabra), St Johns wort (Hypericum perforatum), clove (Syzygium aromaticum), nutmeg (Myristica fragans), ginger (Zingiber officinale), frankincense (Boswellia carteri) and myrrh (Commiphora molmol), further combined with aloe vera and niacin.

Priority: US2004-801520 Applic. Date: 2004-03-16; US20030456817P Applic. Date: 2003-03-21

Inventor: MAZZIO ELIZABETH [US]; SOLIMAN KARAM [US]


Application No.: US20090004623A1  Published: 01/Jan/2009

Title: SUCKBACK PREVENTION DEVICE FOR SINGLE USE HIGH-SPEED TURBINE DENTAL DRILL HANDPIECE

Applicant/Assignee: BEIJING NORTH POLE DENTAL HANDPIECES CO., LTD

Application No.: 12/208480   Filing Date: 11/Sep/2008

Abstract:

A suckback prevention device for single use high-speed turbine dental drill handpiece, installed at the side assembled with the drilling needle of the head housing of the high-speed turbine dental drill handpiece which comprises a head, a drilling needle (3), a front handle (1), and a back handle (2). A powered wind wheel (7) and a wind wheel axle (15) driving the rotation of the drilling needle (3) are installed in the clearance space between the head housing (4) and the head cover (8). The wind wheel axle (15) is supported by the bearing (6). An O-shaped vibration reduction ring is disposed between the bearing (6) and the head housing (4). The upper end of the wind wheel axle (15) is connected orderly to the button cap spring (10) and the button cap (9). A water passage (19), an air passage (20), and a driving wind wheel air passage (12) are set at the neck portion of the head. The compressed air inlet (11) of the driving wind wheel is located in the powered wind wheel (7). The lower end of the wind wheel axle (15) is hidden inside of the head housing (4) and is connected with the drilling needle (3). The edge of the head housing (4) relative to the wind wheel axle (15) and the drilling needle (3) is an annular opening in a two-step profile shape. An elastic bowl-shaped axle shroud (14) is buckled in the inner step of the head housing (4). An eyelet for the drilling needle is set at the center of the axle shroud (14), and the size of the eyelet is slightly larger than the outer diameter of the drilling needle. An annular screw (13) is screwed connected to the outer step of the head housing (4).

Priority: CN20061200741 Applic. Date: 2006-07-25; WO2007CN70113 Applic. Date: 2007-06-14

Inventor: ZHANG FUDONG [CN]


Application No.: US20090004662A1  Published: 01/Jan/2009

Title: METHOD AND COMPOSITIONS FOR NUCLEIC ACID AMPLIFICATION

Applicant/Assignee: APPLERA CORPORATION

Application No.: 12/140142   Filing Date: 16/Jun/2008

Abstract:

The present teachings provide methods, compositions, and kits for nucleic acid amplification. In some embodiments of the present teachings, amplification reactions are performed with at least one high stability primer. In some embodiments, the present teachings provide a method comprising a high stability primer for amplification of a nucleic acid sequence in a sample comprising a target nucleic acid sequence and a PCR inhibitor.

Priority: US20070944708P Applic. Date: 2007-06-18

Inventor: MULERO JULIO J [US]; HENNESSY LORI K [US]


Application No.: US20090005358A1  Published: 01/Jan/2009

Title: Compositions and methods for treating medical conditions

Applicant/Assignee:

Application No.: 12/215005   Filing Date: 24/Jun/2008

Abstract:

The invention features methods, compositions, and kits for the treatment of pain or pruritus in a patient. In one embodiment, the methods, compositions, and kits of the invention provide for a combination therapy including a tricyclic compound and a tetra-substituted pyrimidopyrimidine.

Priority: US20070937282P Applic. Date: 2007-06-26

Inventor: LESSEM JAN [US]


Application No.: US20090005430A1  Published: 01/Jan/2009

Title: Receptor Blocker and Vasodilator Comprising Indole Derivative as Active Ingredient

Applicant/Assignee: NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY THE TOHO UNIVERSITY

Application No.: 11/663748   Filing Date: 16/Sep/2005

Abstract:

It is intended to find a compound that is structurally simpler than yohimbine, a pentacyclic condensed heterocyclic compound, and has an effect similar to that of yohimbine. The present invention relates to a pharmaceutical or food composition for alpha2 receptor blockage comprising a compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: (wherein R1 represents a hydrogen, alkyl group, alkenyl group, alkynyl group, aromatic group, aralkyl group, acyl group, arylsulfonyl group, alkylsulfonyl group, or hydroxyl group

R2 represents a hydrocarbon group

R3, R4, R5, R6, and R7 are the same or different and represent a hydrogen, halogen, alkyl group, or alkoxy group

R8 represents a hydrogen or acyl group

n represents an integer of 1 to 6

and a and b are the same or different and represent 1 or 0).

Priority: JP20040280104 Applic. Date: 2004-09-27; WO2005JP17109 Applic. Date: 2005-09-16

Inventor: SOMEI MASANORI [JP]; SHIGENOBU KOKI [JP]; TANAKA YOSHIO [JP]


Application No.: US20090005452A1  Published: 01/Jan/2009

Title: Diphenyl Urea Derivatives

Applicant/Assignee: ARIPIDA AG ARPIDA AG

Application No.: 12/096831   Filing Date: 08/Dec/2006

Abstract:

The invention relates to novel specifically trifluoromethyl and halogen substituted 1,3-diphenyl ureas and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects like the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as anti-infectives.

Priority: WO2005EP13345 Applic. Date: 2005-12-13; WO2006EP11795 Applic. Date: 2006-12-08

Inventor: LOEWE RALF [CH]; LOCIURO SERGIO [CH]; HAWSER STEPHEN [FR]; SCHMITT LAURENT [FR]


Application No.: US20090005469A1  Published: 01/Jan/2009

Title: Dental Compositions and Initiator Systems with Polycyclic Aromatic Component

Applicant/Assignee:

Application No.: 12/159250   Filing Date: 22/Dec/2006

Abstract:

The invention features a polymerizable composition that comprises a free-radically polymerizable acidic resin, and a photoinitiator system comprising a polycyclic aromatic component. The photoinitiator system may also contain a visible light sensitizer, an iodonium salt, and a tertiary amine.

Priority: US20050754952P Applic. Date: 2005-12-29; WO2006US49249 Applic. Date: 2006-12-22

Inventor: CRAIG BRADLEY D [US]; SHUKLA BRIAN A [US]; OXMAN JOEL D [US]; RUSSELL VICTORIA A [US]


Application No.: US20090007431A1  Published: 08/Jan/2009

Title: METHOD OF MANUFACTURING DENTAL INSTRUMENTS FROM SUPER-ELASTIC ALLOYS

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 12/210539   Filing Date: 15/Sep/2008

Abstract:

Dental instruments and appliances are manufactured from a superelastic alloy, which includes atoms from the group IVB and group VB transition metals and oxygen so as to exhibit superior strength and flexibility. The metal alloys are cold worked to increase the tensile strength of the dental instruments and appliances. Cold working the metal also increases the flexibility of the dental instruments and appliances and prevents work hardening. Dental instruments made from the superelastic alloy exhibit higher strength, flexibility, resistance to work hardening, and biocompatibility compared to dental instruments made from nickel-titanium alloys. In one particular example a super-elastic endodontic file is described.

Priority: US2005-176839 Applic. Date: 2005-07-07; US20040586738P Applic. Date: 2004-07-09

Inventor: FISCHER DAN E [US]


Application No.: US20090010856A1  Published: 08/Jan/2009

Title: Composition, Comprising Hydrofluoric Acid, for Inhibiting Dental Erosion

Applicant/Assignee: IN 2 GROUP AS

Application No.: 11/596104   Filing Date: 18/May/2005

Abstract:

The present invention relates to a composition, for inhibiting dental erosion, and the use thereof. The composition comprises an aqueous solution of hydrofluoric acid, in which the concentration of hydrofluoric acid is 0.05%-2.00% and the pH is between 2.5 and 4.5.

Priority: NO20040002027 Applic. Date: 2004-05-14; WO2005NO00167 Applic. Date: 2005-05-18

Inventor: ROLLA GUNNAR [NO]; THRANE PER STANLEY [NO]


Application No.: US20090010857A1  Published: 08/Jan/2009

Title: Toothpaste Comprising Calcium Carbonate and Zinc Citrate

Applicant/Assignee:

Application No.: 11/658957   Filing Date: 05/Jul/2005

Abstract:

Toothpaste and method for making such, the toothpaste comprising calcium carbonate as abrasive, water and zinc salt substantially all of which is in the form of water-solubilised zinc citrate.

Priority: EP20040254661 Applic. Date: 2004-08-03; WO2005EP07319 Applic. Date: 2005-07-05

Inventor: WATERFIELD PHILIP CHRISTOPHER [GB]


Application No.: US20090010859A1  Published: 08/Jan/2009

Title: Oral Composition

Applicant/Assignee:

Application No.: 11/658956   Filing Date: 13/Jul/2005

Abstract:

A visually clear gel toothpaste composition comprising a sparingly soluble divalent metal salt, characterised in that the sparingly soluble divalent metal salt is fully solubilised by a chelating agent for the metal salt, the chelating agent having a log Ks1 for the divalent metal ion as herein defined of from 3.0 to 7.0.

Priority: EP20040254662 Applic. Date: 2004-08-03; EP20040254661 Applic. Date: 2004-08-03; EP20040257063 Applic. Date: 2004-11-15; EP20040257064 Applic. Date: 2004-11-15; EP20050250131 Applic. Date: 2005-01-13; WO2005EP07722 Applic. Date: 2005-07-13

Inventor: WATERFIELD PHILIP CHRISTOPHER [GB]


Application No.: US20090010958A1  Published: 08/Jan/2009

Title: Compositions effective in altering the perception of malodor

Applicant/Assignee: PATUS LTD

Application No.: 12/230746   Filing Date: 04/Sep/2008

Abstract:

A method of modifying perception of a malodor, such as the stench associated with putrefying flesh, by selectively affecting specific olfactory receptors in an individual is disclosed. Disclosed are articles of manufacture and especially innovative compositions effective in implementing the method of the present invention including at least three plant extracts.

Priority: US2006-579842 Applic. Date: 2006-05-17; WO2004IL01047 Applic. Date: 2004-11-15; US20030520319P Applic. Date: 2003-11-17; US20030526600P Applic. Date: 2003-12-04

Inventor: PINNEY VIRGINIA RUTH [US]


Application No.: US20090010973A1  Published: 08/Jan/2009

Title: Silicas

Applicant/Assignee: INEOS SILICAS LIMITED

Application No.: 12/158234   Filing Date: 12/Dec/2006

Abstract:

Priority: GB20050025369 Applic. Date: 2005-12-14; WO2006GB04649 Applic. Date: 2006-12-12

Inventor: STANIER PETER WILLIAM [GB]


Application No.: US20090010989A1  Published: 08/Jan/2009

Title: Coating For Implants and Implants With Improved Osteointegration, and Manufacturing Method

Applicant/Assignee: N0LABS AB

Application No.: 12/065601   Filing Date: 13/Feb/2006

Abstract:

A coating on an implant, said implant being intended for implantation in/on an implantation area, is provided. The coating comprises nitric oxide (NO) for obtaining an anti-viral, anti-fungal, and anti-bacterial effect, and for promotion of osteo-integration of the implant, bone healing, bone growth, and wound healing at said implantation area. A nitric oxide (NO) eluting polymer is integrated with a carrier material, such that said carrier material, in use, regulates and controls the elution of a therapeutic dosage of nitric oxide (NO). An implant and a kit of implants, comprising said coating are also provided. Furthermore, a manufacturing method for the implant is disclosed.

Priority: US20050716192P Applic. Date: 2005-09-12; WO2006EP50903 Applic. Date: 2006-02-13

Inventor: PETERS TOR [CH]


Application No.: US20090011385A1  Published: 08/Jan/2009

Title: NON-INVASIVE METHOD FOR TREATING PERIODONTAL DISEASE

Applicant/Assignee: CAO GROUP, INC

Application No.: 12/141055   Filing Date: 17/Jun/2008

Abstract:

The present invention is a method of non-invasive treatment of periodontal disease using ultrasonic waves. The treatment involves placing a tray, covering a metal fork, over the arch intended to be treated. The tray holds the metal fork to the teeth and gingival surface. The metal fork is connected to at least one ultrasonic transducer, which is in turn connected to a control unit that controls the delivery of ultrasonic energy. Both upper and lower arches can be treated simultaneously. The tray(s) may be filled with a therapeutic gel or the patient's own saliva maybe permitted to fill the tray and serve as a conductive gel. The ultrasonic waves, both alone or with a therapeutic gel, and heal the diseased tissue without surgery or curettage. Treatment may be repeated as needed or it may be used as a preventative measure with lesser treatment time.

Priority: US2007-961557 Applic. Date: 2007-12-20; US2004-913702 Applic. Date: 2004-08-06; US20080050472P Applic. Date: 2008-05-05

Inventor: JENSEN STEVEN D [US]; CAO DENSEN [US]


Application No.: US20090011387A1  Published: 08/Jan/2009

Title: Method and composition for adhering to tooth structure

Applicant/Assignee:

Application No.: 12/231928   Filing Date: 08/Sep/2008

Abstract:

A dental adhesive composition has an adhesive component and an activator component. The adhesive composition has a volatile organic solvent component, one or more polymerizable (meth)acrylate compounds optionally containing fillers, and a polymerization photoinitiator. The adhesive component may also be a substantially homogeneous mixture of one or more polymerizable (meth)acrylate compounds and an effective amount of a photoinitiator, without a solvent. The activator component includes an aromatic sulfinate salt and an activator component solvent. A method for adhering a restorative to a dental surface includes preparing the surface for restoration

applying a mixture of an adhesive component and an activator component to the prepared cavity, thereby forming a coated cavity surface

and, applying a direct or indirect dental restorative to the coated cavity surface.

Priority: US2007-700461 Applic. Date: 2007-01-31; US2004-945453 Applic. Date: 2004-09-20; US1998-107913 Applic. Date: 1998-06-30

Inventor: SANG JUNJIE [US]; HAMMESFAHR PAUL D [US]


Application No.: US20090011916A1  Published: 08/Jan/2009

Title: STRENGTHENED, PRESSABLE CERAMIC COMPOSITIONS FOR DENTAL PURPOSES

Applicant/Assignee: HERAEUS KULZER GMBH

Application No.: 12/211135   Filing Date: 16/Sep/2008

Abstract:

Pressable glass-ceramic compositions for dental purposes of the composition I, II or III I II III

colname="4" colwidth="42pt" align="center"/>

ZrO2 17-70% ZrO2/Al2O3 15-70% Al2O3 15-70% SiO2 17-59% SiO2 17-59% SiO2 17-59% Al2O3 2-15% ZrO2 2-15% ZrO2 2-15% Y2O3 0-6% Y2O3 0-6% Y2O3 0-6% K2O 3-12.5% K2O 3-12.5% K2O 3-12.5%

Na2O 0.2-8.5% Na2O 0.2-8.5% Na2O 0.2-8.5% Li2O 0-1.5% Li2O 0-1.5% Li2O 0-1.5% CaO 0.3-2% CaO 0.3-2% CaO 0.3-2% B2O3 0.1-5% B2O3 0.1-5% B2O3 0.1-5% F 0-2.5% F 0-2.5% F 0-2.5% CeO2 0.2-2% CeO2 0.2-2% CeO2 0.2-2% TiO2 0-1.5%

TiO2 0-1.5% TiO2 0-1.5%

are particularly suitable for the manufacturing of ceramic veneer frames.

Priority: DE200410010138 Applic. Date: 2004-02-27; US2005-052396 Applic. Date: 2005-02-07

Inventor: STEIDL JURGEN [DE]


Application No.: US20090012209A1  Published: 08/Jan/2009

Title: DENTAL COMPOSITIONS CONTAINING A SURFACE-MODIFIED FILLER

Applicant/Assignee:

Application No.: 11/997788   Filing Date: 31/Jul/2006

Abstract:

The present invention features ionomer compositions containing a filler surface modified with a polyacid. The compositions can be used in a variety of dental and orthodontic applications, for example, as adhesives, cements, restoratives, coatings and sealants.

Priority: US20050706180P Applic. Date: 2005-08-05; WO2006EP07557 Applic. Date: 2006-07-31

Inventor: ECKHARDT GUNTHER [DE]; MIKULLA MARKUS [DE]; PEEZ ROBERT F [DE]; BISSINGER PETER [DE]; GOTTSCHALK-GAUDIG GABRIELE [DE]


Application No.: US20090014018A1  Published: 15/Jan/2009

Title: Coated colloidal ground plant materials

Applicant/Assignee: PHILIP MORRIS USA INC

Application No.: 12/155227   Filing Date: 30/May/2008

Abstract:

A method of providing a comestible plant material taken orally by coating a micronized plant material with a first layer of polysaccharides or proteins, then a second layer of polysaccharides or proteins is disclosed. A bi-encapsulated plant material produced by this process is also disclosed.

Priority: US20070924826P Applic. Date: 2007-06-01

Inventor: SENGUPTA TAPASHI [US]; MISHRA MUNMAYA K [US]; SWEENEY WILLIAM R [US]; FERNANDEZ DOUGLAS A [US]


Application No.: US20090014025A1  Published: 15/Jan/2009

Title: DEVICE FOR CLEANING INTERDENTAL SPACES

Applicant/Assignee:

Application No.: 12/239168   Filing Date: 26/Sep/2008

Abstract:

Individually packaged coils of dental floss are packed in a succession of separable. The package can be a tubular sheet structure with segments formed between transverse lines of attachment at which the floss is cut and the segments are separable by a lateral perforation. Tearing a separated single segment in half allows the floss to be extended between the free ends of the floss, each captured in the remaining portions of the weld lines at opposite ends of the segment. The segments can be formed from two facing sheets with welds along both lateral edges and across the transverse lines between segments. Alternatively, an integral sheet can be folded to form one lateral edge and attached at the other edge. The sheet material can be polymer coated paper or a transparent plastic.

Priority: WO2006RU00153 Applic. Date: 2006-03-31

Inventor: LYULYEV VYACHESLAV MIKHAILOVICH [RU]; PAVELKO SERGEY MAIKOVICH [RU]; SHKURENKO SVETLANA IVANOVNA [RU]


Application No.: US20090016972A1  Published: 15/Jan/2009

Title: Oral cavity care curative and prophylactic composition

Applicant/Assignee:

Application No.: 12/094605   Filing Date: 19/Sep/2008

Abstract:

The invention relates to stomatology and perfume industry in particular to therapeutic formulation for oral cavity care. The invention refers to oral hygiene means and can be applied for preparation of medical and prophylactic tooth-pastes, gels, liquids for oral care as well as other compositions like chewing gums, jellies, etc. Formulation containing orally applicable active and inert components involves bromelain in amount of 0.01/1 wt %, xylitol 1.5/20 wt %. At best bromelain content is 0.1-0.8 wt %, xylitol content-2.2-18 wt %. For attaining remineralizing effect formulation contains anti-carious mineral additive 0.05-3.0 wt % of the list of active components. At best anti-carious mineral additive content is 0.2-2.5 wt %. There are used calcium glycerophosphate and inorganic or organic magnesium salt as anti-carious mineral additive. It is acceptable to use sodium monofluorphosphate, potassium monofluorphosphate, calcium monofluorphosphate or magnesium monofluorphosphate in amount of 0.5-1.5 wt % as anti-carious mineral additive Optimum concentration is 0.8-1.1 wt %.

Priority: WO2005RU00601 Applic. Date: 2005-11-25

Inventor: MANASHEROV TAMAZI OMAROVICH [RU]; MATELO SVETLANA KONSTANTINOVNA [RU]; GROSSER ALEXANDR VLADIMIROVICH [RU]


Application No.: US20090017052A1  Published: 15/Jan/2009

Title: Methods of determining lethality of pathogens and malignancies involving replikin peak genes

Applicant/Assignee:

Application No.: 12/010027   Filing Date: 18/Jan/2008

Abstract:

The present invention provides methods of identifying lethal, virulent and rapidly replicating viruses, organisms, and malignancies comprising comparing Replikin concentrations among different viruses, organisms, or malignancies. The present invention further provides isolated Replikin Peak Genes associated with increased lethality, virulence and rapid replication, for diagnostic, therapeutic and predictive purposes.

Priority: US20070991676P Applic. Date: 2007-11-30; US20070982336P Applic. Date: 2007-10-24; US20070982333P Applic. Date: 2007-10-24; US20070982338P Applic. Date: 2007-10-24; US20070935816P Applic. Date: 2007-08-31; US20070935499P Applic. Date: 2007-08-16; US20070954743P Applic. Date: 2007-08-08; US20070898097P Applic. Date: 2007-01-30; US20070880966P Applic. Date: 2007-01-18

Inventor: BOGOCH SAMUEL [US]; BOGOCH ELENORE S [US]; BOGOCH SAMUEL WINSTON [US]; BORSANYI ANNE ELENORE [US]


Application No.: US20090017101A1  Published: 15/Jan/2009

Title: COMPOSITIONS FOR REMOVING STAINS FROM DENTAL SURFACES AND METHODS OF MAKING AND USING THE SAME

Applicant/Assignee: CADBURY ADAMS USA LLC

Application No.: 12/239161   Filing Date: 26/Sep/2008

Abstract:

Stain-removing oral compositions, such as gum compositions are herein provided. The compositions include a chelating agent and a surfactant. The surfactant includes a fatty acid salt and at least one component selected from nonionic and anionic surfactants. The fatty acid salt may have at least one hydroxyl functionality. The oral compositions may optionally include an abrasive agent.

Priority: US2004-901872 Applic. Date: 2004-07-29; US2003-719602 Applic. Date: 2003-11-21; US2002-285217 Applic. Date: 2002-10-31

Inventor: HOLME SAMANTHA KATHARINE RACHEAL [US]; LUO SHIUH [US]; GEBRESELASSIE PETROS [US]; BOGHANI NAVROZ [US]


Application No.: US20090017414A1  Published: 15/Jan/2009

Title: Dental Handpiece

Applicant/Assignee: AMDENT AB

Application No.: 11/795418   Filing Date: 06/Feb/2006

Abstract:

The present invention relates to a dental handpiece (1

1') which comprises a body (3) intended to be held by an operator, such as a dentist or dental hygienist, an implement (9) being able to be fitted in a front part of the body (3) so that the operator is able to carry out an oral procedure on a patient with the aid of the implement (9) when holding the body, a light source (29) being disposed in the body (3) and intended to emit light for illuminating the patient's oral cavity during the oral procedure. The invention is characterized in that the dental handpiece (1

1') additionally comprises a lens arrangement (33) designed to diffuse the light from the light source (29) within the patient's oral cavity.

Priority: SE20050000281 Applic. Date: 2005-02-07; US20050593695P Applic. Date: 2005-02-07; WO2006SE50004 Applic. Date: 2006-02-06

Inventor: ANDERSSON GORAN [SE]


Application No.: US20090017421A1  Published: 15/Jan/2009

Title: Method of Preparing an Artificial Dental Prosthetic and Seating Thereof

Applicant/Assignee:

Application No.: 12/237133   Filing Date: 24/Sep/2008

Abstract:

An artificial dental prosthetic constructed of a curable resinous dental composition, and a method for preparing and seating the artificial dental prosthetic onto at least one implant in a patient's mouth. The method of preparing the artificial dental prosthetic and seating thereof may be applied to any situation in which one or more artificial dental prosthetic is required, such as a fixed, full artificial dental prosthetic for replacement of a patient's upper and/or lower arches or a fixed, partial artificial dental prosthetic for replacement of a patient's upper and/or lower teeth.

Priority: US2007-734138 Applic. Date: 2007-04-11; US20060863232P Applic. Date: 2006-10-27

Inventor: LETCHER WILLIAM F [US]


Application No.: US20090017423A1  Published: 15/Jan/2009

Title: DROPLET JET SYSTEM FOR CLEANSING

Applicant/Assignee: KONINKLIJKE PHILIPS ELECTRONICS N.V

Application No.: 11/814060   Filing Date: 20/Jan/2005

Abstract:

The system includes a reservoir for fluid

a droplet generator for creating a stream of fluid droplets from the fluid wherein the velocity of the stream of droplets is within a range of 20 meters per second to 200 meters per second and the size of the droplets is within a range of 5 microns to 200 microns. A nozzle or nozzles direct the stream of droplets to safely clean a selected tooth or teeth surface area. The specific momentum of effective fluid droplets within the stream of fluid droplets is important in safe and effective cleaning.

Priority: US20040537690P Applic. Date: 2004-01-20; WO2005IB50244 Applic. Date: 2005-01-20

Inventor: GOTTENBOS BART [NL]; JANSSEN JOZEF JOHANNES MARIA [NL]; DE JAGER MARINUS KAREL JOHANNES [NL]; CENSE ADRIAAN WILLEM [NL]; DUINEVELD PAULUS CORNELIS [NL]; HAYENGA JON W [US]; BRYANT WILLIAM E [US]; DEKKER MARTIJN JEROEN [NL]


Application No.: US20090018042A1  Published: 15/Jan/2009

Title: PROCESS FOR PRODUCING A MULTI-PHASE DETERGENT TABLET

Applicant/Assignee: RECKITT BENCKISER N.V

Application No.: 11/570552   Filing Date: 20/Jun/2005

Abstract:

A process for the manufacture of a detergent tablet comprises filling a recess in a first pre-formed body with a gel

adding a second body to the gel

and allowing/causing the gel to solidify.

Priority: GB20040013800 Applic. Date: 2004-06-19; WO2005GB02405 Applic. Date: 2005-06-20

Inventor: WIEDEMANN RALF [DE]


Application No.: US20090018144A1  Published: 15/Jan/2009

Title: CAPPED PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS

Applicant/Assignee: PARION SCIENCES, INC

Application No.: 12/171814   Filing Date: 11/Jul/2008

Abstract:

The present invention relates to compounds represented by formula (I): where the structural variables are as defined herein. The compounds are useful for promoting hydration of mucosal surfaces.

Priority: US2005-211707 Applic. Date: 2005-08-26; US2004-920410 Applic. Date: 2004-08-18; US20030495725P Applic. Date: 2003-08-18

Inventor: JOHNSON MICHAEL R [US]; MOLINO BRUCE [US]; ZHANG JIANZHONG [US]; SARGENT BRUCE [US]


Application No.: US20090018167A1  Published: 15/Jan/2009

Title: Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states

Applicant/Assignee:

Application No.: 12/229340   Filing Date: 22/Aug/2008

Abstract:

The present invention relates to chalcone and chalcone derivatives and analogs which are useful as angiogenesis inhibitors. The present compounds, which are inexpensive to synthesize, exhibit unexpectedly good activity as angiogenesis inhibitors. The present invention also relates to the use of chalcone and its analogs as antitumor/anticancer agents and to treat a number of conditions or disease states in which angiogenesis is a factor, including angiogenic skin diseases such as psoriasis, acne, rosacea, warts, eczema, hemangiomas, lymphangiogenesis, among numerous others, as well as chronic inflammatory disease such as arthritis.

Priority: US2005-074545 Applic. Date: 2005-03-08; US2002-198786 Applic. Date: 2002-07-18; US2000-748599 Applic. Date: 2000-12-26; US19990171883P Applic. Date: 1999-12-23

Inventor: BOWEN J PHILLIP [US]; ROBINSON THOMAS PHILIP [US]; EHLERS TEDMAN [US]; GOLDSMITH DAVID [US]; ARBISER JACK [US]


Application No.: US20090018921A1  Published: 15/Jan/2009

Title: Taste sampling process and product

Applicant/Assignee: FIRST FLAVOR, INC

Application No.: 12/217533   Filing Date: 07/Jul/2008

Abstract:

A method for marketing a target product having a flavor to a consumer. A consumable film that is distinct from the target product is provided to the consumer using at least one of the following channels: a print advertisement of the target product, a direct mail advertisement of the target product, a print media insert advertising the target product, a dispenser located at a point-of-purchase of the consumer, a display located at the point-of-purchase of the consumer, a coupon for the target product, a channel for test marketing the target product, an advertisement of the target product contained within a package that includes a product different from the product, or an advertisement of the target product attached to the exterior of a package that contains a different product. The consumable film contains at least one water soluble polymer. The consumable film adheres and dissolves in the mouth of the consumer and thereby renders a likeness of the flavor of the target product to the consumer.

Priority: US2005-054668 Applic. Date: 2005-02-09

Inventor: AZIZ ADNAN A [US]; KOPELMAN JOSHUA M [US]; MINKOFF JAY B [US]


Application No.: US20090020134A1  Published: 22/Jan/2009

Title: Apparatus and method for holding and manipulating dental floss

Applicant/Assignee:

Application No.: 11/879672   Filing Date: 18/Jul/2007

Abstract:

An apparatus and method are disclosed for firmly and comfortably holding and manipulating dental floss without obstructing blood flow in the fingers. The apparatus provides a high degree of dexterity and tactile control, thereby allowing the dental floss to be easily positioned anywhere within the mouth, and allowing the positioning to be readily guided by touch. The apparatus includes a pair of elastomeric sleeves, each worn on a user's finger. A length of dental floss is tensioned between the sleeves by wrapping each end of the dental floss around a sleeve (each end also preferably being glued to a sleeve) and then separating the sleeves until the floss is pulled tightly between them. The sleeves are then inserted into the mouth so as to pass the floss between the teeth. In preferred embodiments, texturing is provided on each sleeve to inhibit slippage of the dental floss on the sleeve.

Priority:

Inventor: TOMSIC COREY [US]; TOMSIC TAMMY [US]


Application No.: US20090020440A1  Published: 22/Jan/2009

Title: Packaged dental composition

Applicant/Assignee:

Application No.: 12/284072   Filing Date: 18/Sep/2008

Abstract:

The invention provides a container enclosing an applicator and a dental composition including a volatile organic solvent. The container is sealed. The volatile organic solvent is effectively retained within the container, even after storage at about 43 DEG C. for one week. Preferably the container is made of a copolymer of a cycloolefin and an open chain olefin.

Priority: US20020319581P Applic. Date: 2002-09-27; US2003-668946 Applic. Date: 2003-09-23; US2005-146975 Applic. Date: 2005-06-07; US2006-586798 Applic. Date: 2006-10-26

Inventor: PIERSON PAUL R [US]; HAMMESFAHR PAUL D [US]


Application No.: US20090020535A1  Published: 22/Jan/2009

Title: Capsule For An Item

Applicant/Assignee:

Application No.: 11/779922   Filing Date: 19/Jul/2007

Abstract:

This invention relates generally to capsules for containers, and more particularly to capsules for housing items with beverage containers, such as wine bottles, champagne bottles, beer bottles, liquor bottles, soda bottles, and the like.

Priority:

Inventor: JOUBERT BRAD T [US]; MITTS JONATHAN P [US]


Application No.: US20090022672A1  Published: 22/Jan/2009

Title: FLUORIDE COMPOSITION AND METHODS FOR DENTAL MINERALIZATION

Applicant/Assignee: THE UNIVERSITY OF MELBOURNE

Application No.: 12/162683   Filing Date: 09/Feb/2007

Abstract:

The present invention relates to compositions and methods for mineralizing a dental surface or subsurface including providing a composition including stabilized ACP and a source of fluoride ions.

Priority: AU20060900634 Applic. Date: 2006-02-09; AU20060903531 Applic. Date: 2006-06-30; WO2007AU00141 Applic. Date: 2007-02-09

Inventor: REYNOLDS ERIC CHARLES [AU]


Application No.: US20090022673A1  Published: 22/Jan/2009

Title: Composition and packaging method for animal dental care

Applicant/Assignee:

Application No.: 12/218106   Filing Date: 11/Jul/2008

Abstract:

A comestible, water-based composition containing natural ingredients provides an effective amount of at least one active ingredient selected to reduce the proliferation of bacteria in the mouth of animals to treat and improve the dental health of animals. The composition can be administered to animals in the form of their daily intake of water and may be especially packaged for ready use and consumption by animals in pre-packaged and portable doses. Compositions containing natural ingredients and formulated as toothpastes for animal dental care are also provided.

Priority: US20070959101P Applic. Date: 2007-07-11

Inventor: ALBERT KAREN L [US]


Application No.: US20090022783A1  Published: 22/Jan/2009

Title: siRNA MICROBICIDES FOR PREVENTING AND TREATING DISEASES

Applicant/Assignee: IMMUNE DISEASE INSTITUTE, INC PRESIDENT AND FELLOWS OF HARVARD COLLEGE

Application No.: 11/916334   Filing Date: 05/Jun/2006

Abstract:

The invention provides a microbicidal composition comprising at least one siRNA. The siRNA is an RNA duplex made of one or two molecules. A portion of the siRNA is identical to a target sequence in an essential gene of a virus. The virus may be a herpesvirus, for example, HSV-1 or HSV-2. Preferably, the herpesvirus is HSV-2. The microbicidal composition further comprises a pharmaceutically acceptable carrier. Also included in the invention are methods to prevent and treat viral infections by administration of the microbicidal composition. Preferably, the microbicidal composition is administered transmucosally.

Priority: US20050687216P Applic. Date: 2005-06-03; WO2006US21758 Applic. Date: 2006-06-05

Inventor: LIEBERMAN JUDY [US]; PALLISER DEBORAH [US]; KNIPE DAVID [US]


Application No.: US20090022799A1  Published: 22/Jan/2009

Title: COMPOSITIONS THAT CONTAIN BETA-GLUCAN TO BE USED FOR THE PREVENTION AND TREATMENT OF DISEASE AND METHODS FOR THEIR USE

Applicant/Assignee:

Application No.: 11/867309   Filing Date: 04/Oct/2007

Abstract:

This application for patent discloses beta-Glucan containing compositions, dosage forms, delivery methods, and techniques for the purposes of preventing and treating mucositis through wound healing and tissue re-organization, as well as the treatment of immune disorders such as Alzheimer's disease, Multiple Sclerosis and Parkinson's disease. beta-Glucan containing compositions, dosage forms and methods to deliver therapeutic and prophylactic vaccines and anti-cancer drugs are also disclosed, as are methods to stabilize a drug to enhance its shelf life and to enhance the level and duration of its bioactivity.

Priority: US20060850284P Applic. Date: 2006-10-06

Inventor: BARMAN SHIKHA PRAMANIK [US]


Application No.: US20090023114A1  Published: 22/Jan/2009

Title: Tooth preparation solution and method

Applicant/Assignee:

Application No.: 11/879437   Filing Date: 17/Jul/2007

Abstract:

A method of preparing teeth for the adhesion of a component includes applying to at least one tooth a solution of liquid phosphoric acid and an abrasive such as pumice, removing the solution, and applying an adhesive for placing a component on the teeth.

Priority:

Inventor: BESSON FRANK R [US]


Application No.: US20090023574A1  Published: 22/Jan/2009

Title: Dental glass ceramics

Applicant/Assignee: IVOCLAR VIVADENT AG

Application No.: 11/921816   Filing Date: 31/May/2006

Abstract:

The invention relates to dental glass-ceramics and a process for producing them and their use, with these comprising at least one crystal phase containing xenotime or monazite or mixtures thereof.

Priority: DE200510026269 Applic. Date: 2005-06-08; WO2006EP62761 Applic. Date: 2006-05-31

Inventor: HOLAND WOLFRAM [LI]; RITZBERGER CHRISTIAN [AT]; RHEINBERGER VOLKER [LI]; APEL ELKE [CH]


Application No.: US20090023576A1  Published: 22/Jan/2009

Title: Method for the surface treatment of bead polymers

Applicant/Assignee: BAUER TECHNOLOGIES GMBH

Application No.: 11/911307   Filing Date: 12/Apr/2006

Abstract:

A method for the surface treatment of bead polymers is to be prepared, by means of which bead polymers are treated in a particularly simple and effective manner such that upon addition to unfinished ceramic pieces, in particular, their strength and dimensional stability increase. To this end, the bead polymers are conducted to a device which is used for comminution, in particular, to a mill, in which the surface of the bead polymers is purposefully scratched or roughened in a uniformly mechanical manner.

Priority: DE200510017586 Applic. Date: 2005-04-16; WO2006EP03372 Applic. Date: 2006-04-12

Inventor: KRYTS OTTMAR [DE]


Application No.: US20090023724A1  Published: 22/Jan/2009

Title: Heteroaryl compounds, compositions thereof, and methods of treatment therewith

Applicant/Assignee:

Application No.: 11/975652   Filing Date: 18/Oct/2007

Abstract:

Provided herein are Heteroaryl Compounds having the following structure: wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.

Priority: US20060853166P Applic. Date: 2006-10-19

Inventor: MORTENSEN DEBORAH SUE [US]; DELGADO MEDEROS MARIA MERCEDES [US]; SAPIENZA JOHN JOSEPH [US]; ALBERS RONALD J [US]; LEE BRANDEN G [US]; HARRIS III ROY LEONARD [US]; SHEVLIN GRAZIELLA ISABEL [US]; HUANG DEHUA [US]; SCHWARZ KIMBERLY LYN [US]; PACKARD GARRICK K [US]; PARNES JASON SIMON [US]; PAPA PATRICK WILLIAM [US]; TEHRANI LIDA RADNIA [US]; PERRIN-NINKOVIC SOPHIE [US]; RIGGS JENNIFER R [US]


Application No.: US20090023772A1  Published: 22/Jan/2009

Title: Novel substituted heteroaryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors

Applicant/Assignee:

Application No.: 11/658892   Filing Date: 24/Aug/2005

Abstract:

This invention relates to novel substituted heteroaryloxy alkylamines useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20040001291 Applic. Date: 2004-08-26; US20040605174P Applic. Date: 2004-08-30; WO2005EP54152 Applic. Date: 2005-08-24

Inventor: ERIKSEN BIRGITTE L [DK]; PETERS DAN [DK]; NIELSEN ELSEBET OSTERGAARD [DK]; SCHEEL-KRUGER JORGEN [DK]; OLSEN GUNNAR M [DK]


Application No.: US20090023813A1  Published: 22/Jan/2009

Title: Diphenyl Urea Derivatives

Applicant/Assignee: ARPIDA AG

Application No.: 12/097191   Filing Date: 08/Dec/2006

Abstract:

The invention relates to novel specifically trifluoromethyl and halogen substituted 1,3-diphenyl ureas and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects like the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as anti-infectives.

Priority: WO2005EP13345 Applic. Date: 2005-12-13; WO2006EP11794 Applic. Date: 2006-12-08

Inventor: LOEWE RALF [CH]; LOCIURO SERGIO [CH]; HAWSER STEPHEN [FR]; SCHMITT LAURENT [FR]


Application No.: US20090024082A1  Published: 22/Jan/2009

Title: Time-Indicating Syringe Mixing Devices And Related Methods For Storing and Dispensing Two-Part Dental Compositions

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 12/242555   Filing Date: 30/Sep/2008

Abstract:

Time-indicating syringe mixing systems for mixing, storing, and dispensing a two-part dental composition that becomes less stable upon mixing including a first plunger comprising an elongate stem and a plug at a distal end of the elongate stem, a hollow first chamber configured to contain a first component, a hollow second chamber configured to contain a second component, and means for indicating a recorded date when a first component initially contained within the hollow first chamber is mixed with a second component initially contained within the hollow second chamber. The inventive syringe mixing systems may be configured as syringe-in-syringe systems and/or syringe-to-syringe systems.

Priority: US2007-736457 Applic. Date: 2007-04-17; US2006-414964 Applic. Date: 2006-05-01; US2006-537883 Applic. Date: 2006-10-02; US2007-673334 Applic. Date: 2007-02-09

Inventor: MCLEAN BRUCE S [US]; FISCHER DAN E [US]; JESSOP NEIL [US]


Application No.: US20090025741A1  Published: 29/Jan/2009

Title: Tobacco-free oral flavor delivery pouch product

Applicant/Assignee: PHILIP MORRIS USA INC

Application No.: 12/219118   Filing Date: 16/Jul/2008

Abstract:

Provided is a tobacco-free oral flavor delivery pouch product that provides and engaging and flavorful experience to a user. The pouch product includes a porous pouch wrapper and an inner filling material. The inner filling material can include a non-tobacco, botanical component, at least one functional ingredient and a solid flavor component dispersed throughout the inner filling material. The pouch product delivers multiple textures to the user's mouth.

Priority: US20070929875P Applic. Date: 2007-07-16

Inventor: CRAWFORD DANIELLE R [US]; BROOKS KAREN [US]; NEWMAN KENNETH A [US]; SWEENEY WILLIAM R [US]; CHAPPELL SR FERNANDO L [US]


Application No.: US20090025760A1  Published: 29/Jan/2009

Title: MEDICAL AND DENTAL TOOL CLEANING DEVICE

Applicant/Assignee:

Application No.: 11/782256   Filing Date: 24/Jul/2007

Abstract:

An apparatus for cleaning of dental instruments and medical instruments. The apparatus includes a body for holding such instruments that is biased apart from an immersion tank. The retained instruments can be lowered into the immersion tank by hand operation. After the hand pressure is removed, the instruments are biased to pull out of the immersion bath. The instruments are then blown dry by pressurized gas.

Priority:

Inventor: CIAMPAGLIA OSCAR [US]


Application No.: US20090028629A1  Published: 29/Jan/2009

Title: SPREADABLE FLUID MATERIAL DISPENSER APPARATUS

Applicant/Assignee: INNOVATIVE CONSUMER SOLUTIONS, LLC

Application No.: 12/182259   Filing Date: 30/Jul/2008

Abstract:

A dispenser for fluid material that facilitates spreading of the fluid material is disclosed. The dispenser can comprise a unitary construction, or can be composed of a plurality of components that can be fastened together. Disposable cartridges containing fluid material can be attached to the dispenser, and the material within can be dispensed on a surface. The dispenser provides metered dispensing.

Priority: US2007-847257 Applic. Date: 2007-08-29; US20060823855P Applic. Date: 2006-08-29; US20060823857P Applic. Date: 2006-08-29; US20060823860P Applic. Date: 2006-08-29; US20060823864P Applic. Date: 2006-08-29; US20060823866P Applic. Date: 2006-08-29; US20060823869P Applic. Date: 2006-08-29

Inventor: DEVIRAG FRANCIS KISS [US]; ROSNER ILEEN [US]; ROSNER JONATHAN [US]


Application No.: US20090028855A1  Published: 29/Jan/2009

Title: INHIBITORS OF AKT/PKB WITH ANTI-TUMOR ACTIVITY

Applicant/Assignee: UNIVERSITY OF SOUTH FLORIDA

Application No.: 12/172831   Filing Date: 14/Jul/2008

Abstract:

The subject invention concerns materials and methods for inhibiting the Akt/PKB pathway. In one embodiment, a compound of the invention inhibits kinase activity and/or phosphorylation levels of Akt proteins. The subject invention also concerns methods for inhibiting or killing a cancer cell or other cell in which expression of an Akt protein is elevated or constitutively active, comprising contacting the cell with an effective amount of a compound of formula I. The subject invention also concerns methods for treating cancer or a tumor in a person or animal comprising administering all effective amount of a compound of formula I to the person or animal.

Priority: US20070949365P Applic. Date: 2007-07-12

Inventor: CHENG JIN Q [US]; SUN MEI [US]; SEBTI SAID M [US]


Application No.: US20090028886A1  Published: 29/Jan/2009

Title: Carrier conjugates of gnrh-peptides

Applicant/Assignee: CYTOS BIOTECHNOLOGY AG

Application No.: 11/659221   Filing Date: 04/Aug/2005

Abstract:

The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising a virus like particle (VLP) and at least one GnRH peptide or fragment or variant thereof linked thereto. The invention also provides a process for producing the composition. The compositions of the invention are useful in the production of vaccines for the treatment of GnRH-related diseases and conditions and to efficiently induce immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune responses within the indicated context.

Priority: US20040598581P Applic. Date: 2004-08-04; US20050673396P Applic. Date: 2005-04-21; WO2005EP53858 Applic. Date: 2005-08-04

Inventor: BACHMANN MARTIN F [CH]; FULURIJA ALMA [CH]; JENNINGS GARY [CH]; MEIJERINK EDWIN [NZ]


Application No.: US20090028924A1  Published: 29/Jan/2009

Title: USE OF A POLYSACCHARIDE WHICH IS EXCRETED BY THE VIBRIO DIABOLICUS SPECIES FOR THE REGENERATION AND PROTECTION OF THE PERIODONTIUM

Applicant/Assignee: UNIVERSITE RENE DESCARTES PARIS 5

Application No.: 12/096588   Filing Date: 06/Dec/2007

Abstract:

The invention relates to the use of a polysaccharide which is excreted by the Vibrio diabolicus species for the re-generation and protection of the non-mineralised connective tissue of the periodontium.

Priority: FR20050012415 Applic. Date: 2005-12-07; WO2006FR02667 Applic. Date: 2006-12-06

Inventor: SENNI KARIM [FR]; SINQUIN CORINNE [FR]; COLLIEC-JOUAULT SYLVIA [FR]; GODEAU GASTON-JACQUES [FR]; GUEZENNEC JEAN [FR]


Application No.: US20090029311A1  Published: 29/Jan/2009

Title: METHOD AND APPARATUS FOR WHITENING TEETH

Applicant/Assignee: SMILE STUDIO (UK) LIMITED

Application No.: 12/161840   Filing Date: 24/Jan/2006

Abstract:

An apparatus (1) for use in whitening teeth comprises support means (7) for being worn on a person's body, a source of radiant heat (9) and position adjusting means (5) connected to said source (9) and said support means (7) for enabling the source (9) to be adjusted to and held in a position adjacent to the person's teeth.

Priority: WO2006GB00239 Applic. Date: 2006-01-24

Inventor: CHAN WYMAN [GB]


Application No.: US20090029315A1  Published: 29/Jan/2009

Title: METHOD FOR MANUFACTURING DENTAL IMPLANT AND DENTAL IMPLANT

Applicant/Assignee: SEIKO EPSON CORPORATION

Application No.: 12/179628   Filing Date: 25/Jul/2008

Abstract:

A dental implant capable of reliably preventing elution of metal when the dental implant is applied within an oral cavity and capable of reliably preventing occurrence of mismatching (bumpy occlusion or the like) when the dental implant is fixed in place, and a method for manufacturing the dental implant are provided. In the method for manufacturing a dental implant including an abutment, the abutment is manufactured through the steps including a titanium molded body production step for molding a titanium molded body composition to obtain a titanium molded body, an assembling step for assembling the titanium molded body and a ceramic member together to obtain an assembled body, a degreasing step for degreasing the assembled body so that the titanium molded body is transformed into a titanium degreased body, and a sintering step for sintering the assembled body to transform the titanium degreased body into a titanium member so that the titanium member is firmly fixed to the ceramic member.

Priority: JP20070196495 Applic. Date: 2007-07-27

Inventor: HAYASHI JUNICHI [JP]; ITO MICHIO [JP]


Application No.: US20090029317A1  Published: 29/Jan/2009

Title: METHOD FOR MANUFACTURING DENTAL IMPLANT AND DENTAL IMPLANT

Applicant/Assignee: SEIKO EPSON CORPORATION

Application No.: 12/179842   Filing Date: 25/Jul/2008

Abstract:

A dental implant capable of reliably preventing elution of metal when the dental implant is applied within an oral cavity and capable of reliably preventing occurrence of mismatching (bumpy occlusion or the like) when the dental implant is fixed in place, and a method for manufacturing the dental implant are provided. In the method for manufacturing a dental implant including an abutment, the abutment is manufactured through the steps including a titanium molded body production step for molding a titanium molded body composition to obtain a titanium molded body, a ceramic molded body production step for molding a ceramic molded body composition to obtain a ceramic molded body, an assembling step for assembling the titanium molded body and the ceramic molded body together to obtain an assembled body, a degreasing step for degreasing the assembled body so that the titanium molded body is transformed into a titanium degreased body and the ceramic molded body is transformed into a ceramic degreased body, and a sintering step for sintering the assembled body to transform the titanium degreased body into a titanium member as a sintered body and to transform the ceramic degreased body into a ceramic member as a sintered body so that the titanium member and the ceramic member are firmly fixed and joined together.

Priority: JP20070196497 Applic. Date: 2007-07-27

Inventor: HAYASHI JUNICHI [JP]; ITO MICHIO [JP]


Application No.: US20090029318A1  Published: 29/Jan/2009

Title: DENTAL IMPLANT AND METHOD FOR MANUFACTURING DENTAL IMPLANT

Applicant/Assignee: SEIKO EPSON CORPORATION

Application No.: 12/179913   Filing Date: 25/Jul/2008

Abstract:

A dental implant capable of reliably preventing elution of metal when the dental implant is applied within an oral cavity and capable of reliably preventing occurrence of mismatching (bumpy occlusion or the like) when the dental implant is fixed in place, and a method for manufacturing the dental implant are provided. In the method for manufacturing a dental implant including an abutment, the abutment is manufactured through the steps including a titanium molded body production step for molding a titanium molded body composition to obtain a titanium molded body having one of male and female thread portions, a ceramic molded body production step for molding a ceramic molded body composition to obtain a ceramic molded body having the other thread portion which makes thread coupling with the one thread portion, an assembling step for assembling the titanium molded body and the ceramic molded body together so that the one thread portion makes thread coupling with the other thread portion, to obtain an assembled body, a degreasing step for degreasing the assembled body, and a sintering step for sintering the assembled body thus degreased.

Priority: JP20070196498 Applic. Date: 2007-07-27

Inventor: HAYASHI JUNICHI [JP]; ITO MICHIO [JP]


Application No.: US20090029321A1  Published: 29/Jan/2009

Title: METHOD FOR MAUFACTURING DENTAL IMPLANT AND DENTAL IMPLANT

Applicant/Assignee: SEIKO EPSON CORPORATION

Application No.: 12/179636   Filing Date: 25/Jul/2008

Abstract:

A dental implant capable of reliably preventing elution of metal when the dental implant is applied within an oral cavity and capable of reliably preventing occurrence of mismatching (bumpy occlusion or the like) when the dental implant is fixed in place, and a method for manufacturing the dental implant are provided. In the method for manufacturing a dental implant including an abutment, the abutment is manufactured through the steps including a ceramic molded body production step for molding a ceramic molded body composition to obtain a ceramic molded body, an assembling step for assembling a titanium member and the ceramic molded body together to obtain an assembled body, a degreasing step for degreasing the assembled body so that the ceramic molded body is transformed into a ceramic degreased body, and a sintering step for sintering the assembled body to transform the ceramic degreased body into a ceramic member so that the ceramic member is firmly fixed to the titanium member.

Priority: JP20070196496 Applic. Date: 2007-07-27

Inventor: HAYASHI JUNICHI [JP]; ITO MICHIO [JP]


Application No.: US20090029322A1  Published: 29/Jan/2009

Title: Use of Stem Cells, Method of Tissue Engineering, Use of Dental Tissues and Tooth Biological Substitute

Applicant/Assignee: MASSACHUSETTS GENERAL HOSPITAL

Application No.: 11/630476   Filing Date: 23/Jun/2005

Abstract:

The present invention is related to the use of stem cells of an animal species for obtainment of biological tooth substitute, in whole or in parts, to be implanted in organism of the same animal strain, wherein said stem cells can be adult cells. The present invention still aims to develop a method of tissue engineering for culturing cells capable to form dental tissue for production of a tooth biological substitute. The said dental tissue can used for the treatment of people suffering from loss, fail or lack of these tissues, and also for cosmetic use of those tissues for a morphological modifying on a patient dentition, for example, the patient may desire to, or need to, have a bigger or smaller dentition for any aesthetic reason.

Priority: BR2004PI02659 Applic. Date: 2004-06-23; WO2005BR00121 Applic. Date: 2005-06-23

Inventor: DUAILIBI SILVIO EDUARDO [BR]; DUAILIBI MONICA TALARICO [BR]; YELICK PAMELA C [US]; VACANTI JOSEPH P [US]


Application No.: US20090029992A1  Published: 29/Jan/2009

Title: SUBSTITUTED PYRAZOLE COMPOUNDS

Applicant/Assignee:

Application No.: 12/137355   Filing Date: 11/Jun/2008

Abstract:

Disclosed are protein kinase inhibitors, compositions comprising such inhibitors, and methods of use thereof. More particularly, disclosed are inhibitors of Aurora A (Aurora-2) protein kinase. Also disclosed are methods of treating diseases associated with protein kinases, especially diseases associated with Aurora-2, such as cancer.

Priority: US20070934062P Applic. Date: 2007-06-11; US20070990475P Applic. Date: 2007-11-27

Inventor: AGOSTON GREGORY E [US]; TRESTON ANTHONY M [US]; LADOUCEUR GAETAN [US]; SUWANDI LITA [US]


Application No.: US20090030035A1  Published: 29/Jan/2009

Title: 3-Aryloxy-8-aza-bicyclo[3.2.1]]oct-6-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Applicant/Assignee: NEUROSEARCH A/S

Application No.: 11/921844   Filing Date: 07/Jun/2006

Abstract:

This invention relates to novel 8-aza-bicyclo[3.2.1]oct-6-ene derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000839 Applic. Date: 2005-06-08; WO2006EP62952 Applic. Date: 2006-06-07

Inventor: PETERS DAN [DK]; BROWN DAVID TRISTRAM [DK]; REDROBE JOHN PAUL [DK]; NIELSEN ELSEBET OSTERGAARD [DK]


Application No.: US20090030110A1  Published: 29/Jan/2009

Title: Dental cement composition containing composite particles with grafted polyacidic polymer chains

Applicant/Assignee: DENTSPLY DE TREY GMBH

Application No.: 12/284275   Filing Date: 19/Sep/2008

Abstract:

A dental cement composition comprising (i) a particulate reactive inorganic filler capable of leaching metal ions in the presence of an acid, and (ii) composite particles with grafted polyacidic polymer chains, which are obtainable by a process comprising the following steps: (a) polymerizing one or more free radically polymerizable monomers containing optionally protected acidic groups in the presence of (a1) an initiatior system comprising initiator particles displaying a moiety comprising a radically transferable atom or group as a polymerization initiation site

and (a2) a catalyst facilitating controlledliving polymerisation, and (a3) optionally further polymerizable monomers, for forming a composite particle with grafted optionally protected polyacidic polymer chains

and (b) optionally deprotecting protected acidic groups, for forming composite particles with grafted polyacidic polymer chains.

Priority: EP20040012495 Applic. Date: 2004-05-26; US2005-217542 Applic. Date: 2005-09-01; US20040606114P Applic. Date: 2004-09-01

Inventor: KLEE JOACHIM E [DE]; BRUGGER STEFAN [DE]; WEBER CHRISTOPH [DE]; MULLER AXEL H E [DE]; MORI HIDEHARU [JP]


Application No.: US20090032040A1  Published: 05/Feb/2009

Title: Porous plastic smokeless tobacco substitutes

Applicant/Assignee:

Application No.: 12/079964   Filing Date: 31/Mar/2008

Abstract:

Systems and methods for providing synthetic substitutes for smokeless tobacco are provided. In one form, the application relates to systems for cessation of smokeless tobacco use and methods for making and using same. More particularly, but not exclusively, the application relates to the use of a plurality of porous plastic dispensing members sized and structured to imitate a quantity of smokeless tobacco, such as chewing tobacco. The porous plastic members define a matrix including an internal network of passages in communication with pores on the exterior of the dispensing members. Residing within the matrix is a dispensate imitative of one or more characteristics of smokeless tobacco which is extractable from the matrix upon exposure to a fluid. In one form, the dispensate may be a tobacco derivative including one or more of nicotine, tobacco flavoring, menthol, vitamins, minerals, therapeutic agents, and/or additional flavoring.

Priority: US20070920947P Applic. Date: 2007-03-30

Inventor: LUZENBERG JR ROBERT S [US]


Application No.: US20090032499A1  Published: 05/Feb/2009

Title: Low Friction Coatings for Use in Dental and Medical Devices

Applicant/Assignee: YEDA RESEARCH AND DEVELOPMENT COMPANY LTD HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LT HOLON ACADEMIC INSTITUTE OF TECHNOLOGY

Application No.: 11/920356   Filing Date: 17/May/2006

Abstract:

The present invention provides an article, at least part of it being coated by inorganic fullerene-like (IF) nanoparticles or composite containing such nanoparticles. Preferably, the invention provides an article made of metal, for use in dentistry or medicine e.g. archwire, needle or catheter, having a friction-reducing film, and methods for coating such articles with a friction-reducing film.

Priority: US20050681443P Applic. Date: 2005-05-17; WO2006IL00578 Applic. Date: 2006-05-17

Inventor: TENNE RESHEF [IL]; KATZ ALON [IL]; REDLICH MEIR [IL]; RAPOPORT LEV [IL]


Application No.: US20090032989A1  Published: 05/Feb/2009

Title: HARDENABLE SELF-SUPPORTING STRUCTURES AND METHODS

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 12/250309   Filing Date: 13/Oct/2008

Abstract:

Compositions, particularly for forming dental products, having a hardenable self-supporting structure with sufficient malleability to be subsequently customized into a second shape and then hardened, and methods.

Priority: US2002-219398 Applic. Date: 2002-08-15; US20010312355P Applic. Date: 2001-08-15

Inventor: KARIM NAIMUL [US]; JONES TODD D [US]; LEWANDOWSKI KEVIN M [US]; FANSLER DUANE D [US]; NELSON JAMES M [US]; SALVIEJO-RIVAS MARCELINO [US]; GADDAM BABU N [US]; ABUELYAMAN AHMED S [US]; MITRA SUMITA B [US]


Application No.: US20090033777A1  Published: 05/Feb/2009

Title: IMAGE SENSOR WITH CORNER CUTS

Applicant/Assignee: E2V

Application No.: 11/994403   Filing Date: 15/Jun/2006

Abstract:

The invention relates to image sensors using a chip with cut corners. The sensor comprises a chip with cut corners comprising a matrix (10) of horizontal lines and vertical columns of photosensitive members, the matrix having a generally rectangular shape of horizontal width W and having four bevels, the sensor comprising as many current or voltage read blocks as there are matrix columns, in order to read the image signals detected by the photosensitive members, characterized in that the current or voltage read blocks are placed in a row (30, 30') along a horizontal edge of the matrix of width W' and are all housed within a vertical strip, the width W1 of which is substantially less than the maximum width W of the matrix. There are two superposed rows of current read blocks with blocks distributed at the same pitch as the pixel columns, or there is a single row with read blocks distributed with a pitch less than that of the pixel columns. The invention can be applied to CMOS technology intraoral radiological sensors.

Priority: FR20050007035 Applic. Date: 2005-07-01; WO2006EP63251 Applic. Date: 2006-06-15

Inventor: LIGOZAT THIERRY [FR]; CHENEBAUX GREGOIRE [FR]


Application No.: US20090035226A1  Published: 05/Feb/2009

Title: USE OF CRANBERRY EXTRACT ENRICHED IN TOTAL PHENOLS AND FREE, ESSENTIALLY FREE, OR SUBSTANTIALLY FREE OF SUGARS, ACIDS, SULFUR AND OTHER CONTAMINANTS, FOR PERIODONTAL TREATMENT

Applicant/Assignee: PHENOLICS, LLC

Application No.: 12/183943   Filing Date: 31/Jul/2008

Abstract:

Cranberry and other plant extracts enriched in total phenols and free or substantially free of sugars, acids, sulfur and other contaminants are used for periodontal treatments. The periodontal treatments of the present invention include swish and swallow techniques, in which the extracts enriched in total phenols but free or substantially free of sugars, acids, sulfur and other contaminants, are solubilized in water or other solvent, placed in the mouth, swished around the teeth and then swallowed. Other application techniques include gel applications, gum formulations and toothpaste formulations.

Priority: US20070953143P Applic. Date: 2007-07-31

Inventor: TEMPESTA MICHAEL S [US]; DAUGHERTY F JOSEPH [US]


Application No.: US20090035228A1  Published: 05/Feb/2009

Title: SKIN AND SURFACE DISINFECTANT COMPOSITIONS CONTAINING BOTANICALS

Applicant/Assignee:

Application No.: 12/016788   Filing Date: 18/Jan/2008

Abstract:

The present invention relates to a skin or surface disinfectant composition with broad spectrum antimicrobial activity comprising one or more essential oil (and/or one or more component thereof) and one or more fruit acid. The compositions of the invention may be used as non-toxic alternatives to conventional disinfectants or may be added to other antimicrobial agents to enhance their activity. The invention provides effective alternatives to harsher products which may be particularly useful in personal care and household products and where children and/or pet exposure may be a concern.

Priority: US20070953654P Applic. Date: 2007-08-02

Inventor: MODAK SHANTA [US]; BAIJU NAYANA [US]; CARAOS LAUSERPINA [US]


Application No.: US20090035229A1  Published: 05/Feb/2009

Title: PHARMACEUTICAL COMPOSITION FOR IMPROVING ORAL HYGIENE AND METHODS THEREOF

Applicant/Assignee:

Application No.: 11/833530   Filing Date: 03/Aug/2007

Abstract:

An aqueous based pharmaceutical composition for use as a oral hygienic treatment is described. The composition contains a pharmaceutically effective amount of a tetracycline-based antibiotic

a water-soluble calcium salt that aids in solubilizing the tetracycline-based antibiotic

a thickener

a pH adjustment agent

an antifoaming agent

an excipient

a surfactant

a preservative

and a flavoring agent. A method of making the aqueous based pharmaceutical composition includes the steps of adjusting, defoaming, dispensing, dispersing, dissolving, flavoring, heating, minimizing, pouring, solubilizing, suspending, and sweetening. A method of using the aqueous based pharmaceutical composition is also disclosed which includes the steps of expectorating, gargling, obtaining, pouring, receiving, and swishing.

Priority:

Inventor: EIREW GARY H [US]


Application No.: US20090035251A1  Published: 05/Feb/2009

Title: METHOD OF APPLYING AN INJECTABLE FILLER

Applicant/Assignee:

Application No.: 12/184966   Filing Date: 01/Aug/2008

Abstract:

Methods for applying injectable fillers are provided. In some embodiments, the methods can extend effectiveness of the injectable filler. In some embodiments, the methods can provide for an elevated level of effectiveness of the injectable filler. In some embodiments, the methods can prolong the effectiveness of the injectable filler.

Priority: US20070953661P Applic. Date: 2007-08-02

Inventor: WORTZMAN MITCHELL S [US]; NARINS RHODA [US]; LIN XIAOMING [US]


Application No.: US20090035282A1  Published: 05/Feb/2009

Title: Pluripotent embryonic-like stem cells derived from teeth and uses thereof

Applicant/Assignee: STIFTUNG CAESAR

Application No.: 12/068695   Filing Date: 11/Feb/2008

Abstract:

A stem cell which is obtainable from the non-embryonic tissue isolated from the dental follicle of tooth or wisdom tooth which are able to differentiate into a periodontal ligament like membrane structure.

Priority: US2005-497206 Applic. Date: 2005-01-10; WO2003EP01131 Applic. Date: 2003-02-05; US20020354152P Applic. Date: 2002-02-06

Inventor: SCHIERHOLZ JORG [DE]; ZEILHOFER HANS-FLORIAN [CH]; HOFFMANN KARL-HEINZ [DE]; MORSCZECK CHRISTIAN [DE]; BRENNER NORBERT [DE]


Application No.: US20090035341A1  Published: 05/Feb/2009

Title: COATING MATERIAL

Applicant/Assignee:

Application No.: 10/580300   Filing Date: 17/Nov/2004

Abstract:

The invention relates to an antimicrobial and preferably non-cytotoxic coating material and to use of said coating material.

Priority: DE20031053756 Applic. Date: 2003-11-17; WO2004EP13030 Applic. Date: 2004-11-17

Inventor: WAGENER MICHAEL [DE]; VISSING KLAUS DIETER [DE]; SALZ DIRK [DE]; STEINRUCKE PETER [DE]


Application No.: US20090035376A1  Published: 05/Feb/2009

Title: Stem cells obtained from pulp of deciduous or permanent teeth and of dental germ, able to produce human bone tissue

Applicant/Assignee:

Application No.: 11/658524   Filing Date: 27/Jul/2005

Abstract:

In this invention is described a method that foresees the isolation of a new subpopulation of stem cells derived form dental pulp, whose differentiation is osteoblasts lead to the subsequent production and employment of a bone tissue, called LAB (Living Autologous Bone). Specifically, the invention describes: 1) the isolation of stem cells from the pulp of deciduous and permanent teeth and of dental germs, obtained from human subjects

2) the growth of these cells in vitro, under specific conditions that allow the isolation of a cellular sub-population, which, after differentiation in osteoblasts, is able to produce in vitro an extracellular matrix, identical to that detectable in bone tissue

3) the use of this selected and differentiated cell population in order to produce autologous bone tissue in vitro, containing vital osteoblasts

4) the preservation of the LAB under conditions which guarantee cellular vitality

5) the use of the LAB in donor patients to reconstruct bone tissue, as required in the daily practice in dentistry, maxillo-facial surgery and orthopedics.

Priority: IT2004NA00043 Applic. Date: 2004-07-28; WO2005EP08136 Applic. Date: 2005-07-27

Inventor: CARINCI FRANCESCO [IT]; D AQUINO RICCARDO [IT]; DE ROSA ALFREDO [IT]; GRAZIANO ANTONIO [IT]; LAINO GREGORIO [IT]; PAPACCIO GIANPAOLO [IT]


Application No.: US20090035714A1  Published: 05/Feb/2009

Title: Methods and systems for concurrent tooth repositioning and substance delivery

Applicant/Assignee:

Application No.: 12/286193   Filing Date: 29/Sep/2008

Abstract:

The present invention provides devices, systems and methods for orthodontic treatment using elastic repositioning appliances while concurrently providing dental and periodontal therapies. Such therapies are traditionally provided with the use of a variety of accessories and devices which are applied when the repositioning appliance is removed from the patient's mouth. The present invention eliminates the need for such removal and additional devices by incorporating these therapies into the repositioning appliance.

Priority: US2007-745211 Applic. Date: 2007-05-07; US2000-666783 Applic. Date: 2000-09-21

Inventor: KUO ERIC [US]; PHAN LOC X [US]


Application No.: US20090035725A1  Published: 05/Feb/2009

Title: PHOTODISINFECTION OF ORAL CAVITY

Applicant/Assignee: ONDINE INTERNATIONAL, LTD

Application No.: 12/179977   Filing Date: 25/Jul/2008

Abstract:

A composition for photodisinfection of the oral cavity comprising toothpaste and a photosensitizing composition encapsulated within microspheres, wherein the microspheres release the photosensitizing composition into the oral cavity upon contact with liquid and/or force and the photosensitizing composition includes a photosensitizer that upon irradiation of at least one predetermined wavelength will reduce and/or eliminate microbes in the oral cavity. The present invention also includes a method of applying the composition into the oral cavity and applying irradiation to the oral cavity at a wavelength or wavelengths absorbed by the photosensitizing composition so as to reduce or eliminate microbes in the oral cavity.

Priority: US20070953541P Applic. Date: 2007-08-02

Inventor: LOEBEL NICHOLAS G [US]; STREET CALE [US]


Application No.: US20090035726A1  Published: 05/Feb/2009

Title: Dental Prosthesis

Applicant/Assignee:

Application No.: 11/575918   Filing Date: 08/Jun/2006

Abstract:

The method for producing ceramic coping of the present invention comprises the following steps: (i) covering a tooth model with at least one layer of plastic

(ii) coating a plastic covered tooth model from step (i) with alumina gel and letting it dry to form a ceramic coping in green state

(iii) sintering the ceramic coping in green state from step (ii) at a temperature up to 1200 DEG C.

(iv) coating the ceramic coping from step (iii) with crystal hardening powder

(v) firing the crystal hardening powder coated ceramic coping from step (iv) at a temperature up to 1200 DEG C. for effecting crystal hardening of the ceramic coping. Then, the finished ceramic coping can be coated with an outer aesthetic layer to form a dental prosthesis.

Priority: WO2006IB01509 Applic. Date: 2006-06-08; MY20050003268 Applic. Date: 2005-07-18

Inventor: BOZDEMIR ADNAN [MY]


Application No.: US20090035728A1  Published: 05/Feb/2009

Title: SELF-ETCHING EMULSION DENTAL COMPOSITIONS AND METHODS

Applicant/Assignee: 3M ESPE AG 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 12/248338   Filing Date: 09/Oct/2008

Abstract:

The present invention is directed to dental compositions that can be used as adhesives for bonding a dental material to a dental structure surface and/or as a dental restorative material. The dental composition is preferably applied to a dental structure surface under conditions effective to etch the dental structure surface.

Priority: US2004-916169 Applic. Date: 2004-08-11; US20030494603P Applic. Date: 2003-08-12

Inventor: AASEN STEVEN M [US]; ABUELYAMAN AHMED S [US]; CINADER JR DAVID K [US]; GRUPP HENDRIK M [DE]; HANSEN MIRIAM [DE]; KLETTKE THOMAS [DE]; LECHNER GUENTHER [DE]; LEWANDOWSKI KEVIN M [US]; LUCHTERHANDT THOMAS [DE]; MITRA SUMITA B [US]; RAO PRABHAKARA S [US]; RUSSELL VICTORIA A [US]; WENDLAND MICHAEL S [US]


Application No.: US20090036456A1  Published: 05/Feb/2009

Title: 3,9-DIAZABICYCLO[3.3.1]NONANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS

Applicant/Assignee: NEUROSEARCH A/S

Application No.: 12/161905   Filing Date: 09/Feb/2007

Abstract:

This invention relates to novel 3,9-diazabicyclo[3.3.1]nonane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20060000189 Applic. Date: 2006-02-10; DK20060000192 Applic. Date: 2006-02-10; US20060771892P Applic. Date: 2006-02-10; US20060771891P Applic. Date: 2006-02-10; WO2007EP51270 Applic. Date: 2007-02-09

Inventor: PETERS DAN [SE]; REDROBE JOHN PAUL [DK]; NIELSEN ELSEBET OSTERGAARD [DK]


Application No.: US20090036458A1  Published: 05/Feb/2009

Title: ENDOPARASITICIDAL TOPICAL COMPOSITIONS

Applicant/Assignee: WYETH

Application No.: 12/182253   Filing Date: 30/Jul/2008

Abstract:

The present invention provides a composition which comprises: an effective amount of (a) praziquantel and (b) a second endoparasiticidal agent selected from the group consisting of a macrocyclic lactone, imidacloprid and a combination thereof

and (c) 4-allyl-2-methoxyphenol as carrier. Also provided is a method for the treatment of endoparasitic infection and infestation in a homeothermic animal.

Priority: US20070962754P Applic. Date: 2007-07-31

Inventor: FATTOHI NAHLA [US]; LAWRENCE MOSES COLUMBUS [US]; SABNIS SHOBHAN SHASHIKANT [US]


Application No.: US20090036477A1  Published: 05/Feb/2009

Title: Novel 3-Aza-Spiro[5,5]Undec-8-Ene Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee:

Application No.: 11/922929   Filing Date: 28/Jun/2006

Abstract:

This invention relates to novel 3-aza-spiro[5.5]undec-8-ene derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000959 Applic. Date: 2005-06-28; US20050594679P Applic. Date: 2005-04-28; WO2006EP63633 Applic. Date: 2006-06-28

Inventor: ERIKSEN BIRGITTE L [DK]; PETERS DAN [SE]; NIELSEN ELSEBET OSTERGAARD [DK]; REDROBE JOHN PAUL [DK]


Application No.: US20090036545A1  Published: 05/Feb/2009

Title: Skin appearance through gene manipulation

Applicant/Assignee:

Application No.: 12/286033   Filing Date: 26/Sep/2008

Abstract:

The present invention relates to a method for treating, preventing and improving the condition and/or aesthetic appearance of aging skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, through meroterpene induced gene manipulation.

Priority: US2007-803188 Applic. Date: 2007-05-14; US2007-986719 Applic. Date: 2007-11-26

Inventor: CHAUDHURI RATAN K [US]


Application No.: US20090036565A1  Published: 05/Feb/2009

Title: Dental Composites with a Low Shrinkage Tension and High Flexural Strength

Applicant/Assignee: HERAEUS KULZER GMBH

Application No.: 12/168512   Filing Date: 07/Jul/2008

Abstract:

Dental composite materials based on (meth)acrylate, exhibiting a proportion of TCD monomers in the total composition of 1-15% by weight and the quotient of flexural strength/shrinkage tension is at least 35.

Priority: DE200710034457 Applic. Date: 2007-07-20

Inventor: UTTERODT ANDREAS [DE]; RUPPERT KLAUS [DE]; SCHAUB MATTHIAS [DE]; DIEFENBACH CHRISTINE [DE]; REISCHL KURT [DE]; HOHMANN ALFRED [DE]; ECK MICHAEL [DE]; SCHONHOF NELLI [DE]; SCHNEIDER JUTTA [DE]


Application No.: US20090036653A1  Published: 05/Feb/2009

Title: Methods for the directed expansion of epitopes for use as antibody ligands

Applicant/Assignee: PEPTIMMUNE, INC

Application No.: 12/151762   Filing Date: 07/May/2008

Abstract:

The instant invention comprises a process for selecting and manufacturing antibodies useful for therapeutic, prophylactic, diagnostic or research purposes using epitope peptide mixtures synthesized by the solid phase synthesis, such process defined by a set of rules regarding the identity and the frequency of occurrence of amino acids that substitute a base or native amino acid of a known epitope. The resulting antibodies are related to but distinct from antibodies that bind to the known epitope.

Priority: US2007-787229 Applic. Date: 2007-04-13; US20070928225P Applic. Date: 2007-05-07; US20070999283P Applic. Date: 2007-10-16; US20070999284P Applic. Date: 2007-10-16; US20080124689P Applic. Date: 2008-04-17; US20060792085P Applic. Date: 2006-04-13

Inventor: BONNIN DUSTAN [US]


Application No.: US20090038619A1  Published: 12/Feb/2009

Title: FULL FACE RESPIRATORY MASK WITH INTEGRATED NASAL INTERFACE

Applicant/Assignee: KONINKLIJKE PHILIPS ELECTRONICS N.V

Application No.: 12/256059   Filing Date: 22/Oct/2008

Abstract:

A patient interface that reliably and comfortably seals a user's face by providing an oral-nasal mask that includes an integrated nasal interface. The patient interface includes a seal member having an oral cushion portion configured to surround the user's mouth and a nasal interface portion that provides an interface with the user's nose. The seal member, including the oral cushion portion and the nasal interface portion, is a unitary member. Finally, the nasal interface portion remains below the bridge of the nose.

Priority: US2006-633888 Applic. Date: 2006-12-05; US20050748311P Applic. Date: 2005-12-07

Inventor: HO PETER CHI FAI [US]; EATON JASON P [US]


Application No.: US20090038635A1  Published: 12/Feb/2009

Title: DISPOSABLE DENTAL APPLIANCE

Applicant/Assignee: ICC INNOVATIVE CONCEPTS CORPORATION

Application No.: 12/170425   Filing Date: 09/Jul/2008

Abstract:

A disposable device for cleaning teeth which incorporates cleaning and/or fluoride components is disclosed. An open compartment defines an elongated volume and an elongated opening extending around the periphery of the top of the volume. A flange is disposed adjacent to the periphery of the top of the volume. The flange is integral with the compartment. This compartment is configured to be substantially flat. A closure member is disposed over the flange. This closure member is secured around the entire periphery of the top of the volume. The closure member may be removed when it is so desired. The compartment can be sealed. The tubular member is contained in the compartment. A quantity of toothpaste is disposed in the compartment.

Priority:

Inventor: CANINO SERAFINO [US]; GELORMINO SCOTT [US]


Application No.: US20090039050A1  Published: 12/Feb/2009

Title: Baby bottle apparatus with powder charge to make beverage

Applicant/Assignee:

Application No.: 12/214275   Filing Date: 17/Jun/2008

Abstract:

Apparatus for administering a liquid formulation to a baby or child includes a bottle charged with water, a dispensing valve mounted on the bottle, and a dust cover that extends over and protects the dispensing valve. The dust cover is hollow and is charged with powder that is mixed with water in the bottle to produce the liquid formulation.

Priority: US2005-259967 Applic. Date: 2005-10-26; US2004-998480 Applic. Date: 2004-11-29; US20050673746P Applic. Date: 2005-04-21; US20070934992P Applic. Date: 2007-06-18; US20080072314P Applic. Date: 2008-03-28

Inventor: REA DONALD J [US]; BARGMAN RONALD D [US]


Application No.: US20090041680A1  Published: 12/Feb/2009

Title: Wax Foamable Vehicle and Pharmaceutical Compositions Thereof

Applicant/Assignee: FOAMIX LTD

Application No.: 12/187840   Filing Date: 07/Aug/2008

Abstract:

Unique foamable vehicles or carriers comprising at least one wax, waxy substance, counterpart or derivative, a stabilizer, water, and a propellant are provided. In some embodiments, the wax is a liquid wax. In some embodiments, the wax includes a solid wax and a liquid wax. The compositions are substantially free of crystals. The components are selected to provide a composition that is substantially resistant to aging and to phase separation, and/or can substantially solubilize and or stabilize active ingredients. Pharmaceutical and cosmetic compositions with potentially enhanced skin delivery and their uses are also provided.

Priority: US20070954525P Applic. Date: 2007-08-07

Inventor: TAMARKIN DOV [IL]; KEYNAN RITA [IL]; SCHUZ DAVID [IL]; BERMAN TAL [IL]


Application No.: US20090042114A1  Published: 12/Feb/2009

Title: Halogenated oxime derivatives and the use therof as latent acids

Applicant/Assignee:

Application No.: 12/154333   Filing Date: 22/May/2008

Abstract:

Compounds of the formula I or II wherein R1 is C1-C10haloalkylsulfonyl, halobenzenesulfonyl, C2-C10haloalkanoyl, halobenzoyl

R2 is halogen or C1-C10haloalkyl

Ar1 is phenyl, biphenylyl, fluorenyl, naphthyl, anthracyl, phenanthryl, or heteroaryl, all of which are optionally substituted

Ar'1 is for example phenylene, naphthylene, diphenylene, heteroarylene, oxydiphenylene, phenylene-D-D1-D-phenylene or -Ar''1-A1-Y1-A1-Ar''1-

wherein these radicals optionally are substituted

Ar''1 is phenylene, naphthylene, anthracylene, phenanthrylene, or heteroarylene, all optionally substituted

A1 is for example a direct bond, -O-, -S-, or -NR6-

Y1 inter alia is C1-C18alkylene

X is halogen

D is for example -O-, -S- or -NR6-

D1 inter alia is C1-C18alkylene

are particularly suitable as photolatent acids in ArF resist technology.

Priority: EP20030405103 Applic. Date: 2003-02-19; EP20030405130 Applic. Date: 2003-02-27; EP20030405432 Applic. Date: 2003-06-17; US2005-543429 Applic. Date: 2005-07-26; WO2004EP50096 Applic. Date: 2004-02-09

Inventor: YAMATO HITOSHI [JP]; ASAKURA TOSHIKAGE [JP]; MATSUMOTO AKIRA [JP]; MURER PETER [CH]; HINTERMANN TOBIAS [CH]


Application No.: US20090042161A1  Published: 12/Feb/2009

Title: Reshapable device for fixation at a dental site

Applicant/Assignee:

Application No.: 11/890986   Filing Date: 08/Aug/2007

Abstract:

A reshapable retention device for insertion at a dental site and contact with adjacent dental surfaces, for the controlled delivery to the dental site of at least one material having a predetermined intraoral activity. The retention device comprises at least one matrix containing the material. The retention device is adapted for physically affixing at the dental site for at least a predetermined time period correlated to the delivery of a predetermined portion of the at least one matrix to the dental site in a controlled single, bi or multiphase pattern. The retention device comprises a first configuration in which the overall dimensions of the retention device are larger than at least one dimension of the dental site. The first configuration is reshapable to a second configuration in which at least one dimension of the retention device is reduced to enable physically affixing the retention device at the dental site. In the second configuration the retention device comprises a predetermined shape having contours for affixing at the dental surfaces.

Priority:

Inventor: JODAIKIN AHRON [IL]; JODAIKIN HILARY [IL]


Application No.: US20090042169A1  Published: 12/Feb/2009

Title: PREDOMINANTLY PLATELET-SHAPED, SPARINGLY WATER-SOLUBLE CALCIUM SALTS AND/OR COMPOSITE MATERIALS THEREOF COMPRISING THEM

Applicant/Assignee:

Application No.: 12/241718   Filing Date: 30/Sep/2008

Abstract:

The invention relates to sparingly water-soluble calcium salts and/or composite materials comprising them, characterized in that the calcium salts are present in the form of single crystals or in the form of particles comprising a multitude of said crystals and having a mean particle diameter in the region of below 1,000 nm, preferably below 300 nm, the calcium salt particles being predominantly platelet-like. The inventive calcium salts and/or composite materials comprising these calcium salts, owing to their composition and fine structure, are particularly suitable for promoting the restoration of bone and tooth material, especially enamel and dentine.

Priority: DE200610009799 Applic. Date: 2006-03-01; WO2006EP10235 Applic. Date: 2006-10-24

Inventor: KINTRUP LOTHAR [DE]; ESCHEN BURKHARD [DE]; HERMANN MARTINA [DE]; FRANKE HOLGER [DE]


Application No.: US20090042756A1  Published: 12/Feb/2009

Title: Dental Appliance Cleansing Composition

Applicant/Assignee:

Application No.: 12/189160   Filing Date: 10/Aug/2008

Abstract:

A novel and safe composition has been discovered that is effective for cleaning dental appliances (e.g. removable braces, retainers, dentures, etc.). This composition bleaches, disinfects, and deodorizes the appliance, while removing plaque that has accumulated on the appliance during wear. The composition comprises a chloramine bleaching agent that liberates hypochlorous acid upon contact with water, a surfactant, a water-soluble carboxylic acid and an alkaline base to produce effervescence and regulate pH, a sequestering agent for alkaline earth metal ions, a drying agent, and an indicator dye that signifies the end of the cleansing process. In a preferred method of using this invention, the premixed components are added to water, and the dental appliance is submerged in the resulting effervescent solution until a color change indicates that cleaning is complete. This invention provides a safe, effective, and convenient method for cleansing and disinfecting dental appliances.

Priority: US20070954942P Applic. Date: 2007-08-09

Inventor: MUZIK LYNN [US]; CONLEY NICHOLAS [US]


Application No.: US20090042890A1  Published: 12/Feb/2009

Title: Heteroaryl compounds, compositions thereof, and methods of treatment therewith

Applicant/Assignee:

Application No.: 11/975657   Filing Date: 18/Oct/2007

Abstract:

Provided herein are Heteroaryl Compounds having the following structure: wherein R1, R3, R4, L, X, Y, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.

Priority: US20060853135P Applic. Date: 2006-10-19

Inventor: MORTENSEN DEBORAH SUE [US]; DELGADO MEDEROS MARIA MERCEDES [US]; SAPIENZA JOHN JOSEPH [US]; ALBERS RONALD J [US]; CLAREEN STEVEN SPENCER [US]; SCHWARZ KIMBERLY LYN [US]; PARNES JASON SIMON [US]; RIGGS JENNIFER R [US]; PAPA PATRICK WILLIAM [US]; HEGDE SAYEE GAJANAN [US]; MCKENNA JEFFREY MARK [GB]


Application No.: US20090042928A1  Published: 12/Feb/2009

Title: Modulators of muscarinic receptors

Applicant/Assignee:

Application No.: 12/215367   Filing Date: 26/Jun/2008

Abstract:

The modulator compounds described herein modulate muscarinic receptors and are useful for treating muscarinic receptor mediated diseases.

Priority: US2004-005944 Applic. Date: 2004-12-07; US20030528049P Applic. Date: 2003-12-09

Inventor: GROOTENHUIS PETER D J [US]; BLANCO MIGUEL GARCIA-GUZMAN [US]; MAKINGS LEWIS R [US]; LONDO PHILIP MARTIN [US]


Application No.: US20090046884A1  Published: 19/Feb/2009

Title: HEADSET MADE FROM RECYCLABLE ISOLATING MATERIALS

Applicant/Assignee:

Application No.: 11/838957   Filing Date: 15/Aug/2007

Abstract:

Headset made from recyclable, disposable and isolating materials such as, for example, paper, cardboard and the like. The headset may comprise ear-members integrated with ear-fasteners and an oblong connecting strip made from isolating materials that may be connected to an ear-member at each end. The ear-members and the connecting-strip may hold at least one speaker connected by conductive-means to an audio player, where each speaker may be seated substantially at the central area of each ear-member. The ear-fasteners may fasten the headset to a user's ear-auricle to enable holding the entire headset over the user's head.

Priority:

Inventor: SCHAPIRO EDUARDO [IL]


Application No.: US20090047221A1  Published: 19/Feb/2009

Title: COMPOUNDS AND COMPOSITIONS USEFUL IN THE TREATMENT OF NEOPLASIA

Applicant/Assignee: NIPRI LIMITED

Application No.: 11/718314   Filing Date: 31/Oct/2004

Abstract:

There is described compounds for use in therapy, said compounds being defined by Formula (1): There is also described an anti-proliferative composition comprising one or more compounds according to Formula (1), and a method of treatment of neoplasia comprising the administration of such a compound or composition.

Priority: GB20040024051 Applic. Date: 2004-10-29; WO2005GB04190 Applic. Date: 2005-10-31

Inventor: MCCLAY ALLEN [GB]; WAUGH DAVID [GB]; ARMSTRONG PAUL [GB]; DELBEDERI ZOICA [GB]; HIGGINS CATHERINE [IE]; VAN DEN BERG HENDRIK [GB]; JOHNSTON PATRICK [GB]; WATTERS WILLIAM [GB]; MCGAREL KELLY [GB]; MILS TIMOTHY [GB]


Application No.: US20090047620A1  Published: 19/Feb/2009

Title: ANTI-MICROBIAL DENTAL IMPRESSION MATERIAL

Applicant/Assignee:

Application No.: 12/093869   Filing Date: 09/Nov/2006

Abstract:

The invention relates to plastics which are self-disinfecting. The invention relates in particular to polyether or silicone based dental plastics and impression materials in which a biocidal material is incorporated. The dental impression material ace. to the invention comprises at least a polymerizable base paste BP and a non-aqueous catalyst paste CP, wherein the base paste BP comprises about 0.001 to about 10% by weight of a water-stable anti-microbial agent. Preferred anti-microbial agents are selected from the group consisting of Hexitidin, Cetypyridininumcloride (CPC), Chlorhexidine and its derivates (CHX) and Triclosan.

Priority: EP20050025182 Applic. Date: 2005-11-17; WO2006US43770 Applic. Date: 2006-11-09

Inventor: KLETTKE THOMAS [DE]; KAPPLER OLIVER [DE]; HAEBERLEIN INGO R [DE]


Application No.: US20090047624A1  Published: 19/Feb/2009

Title: Ultrasonic scaler

Applicant/Assignee:

Application No.: 11/889465   Filing Date: 13/Aug/2007

Abstract:

A RFID (Radio Frequency Identification) reader is installed in the main unit of an ultrasonic scaler, which synchronizes with the antenna installed in the handpiece. Inside of The TIP (Insert or Piezo hand piece) consists of a tag, which uses RFID technology to read, write, and identify the information of the insert or tip. This provides the medical clinicians useful operation assistance, the necessary evidence on when to change to a new insert or tip, and to prevent improper usage of the insert or tip.

Priority:

Inventor: TSAI CHIH-I [TW]


Application No.: US20090047633A1  Published: 19/Feb/2009

Title: Dental compositions for coating restorations and tooth surfaces

Applicant/Assignee:

Application No.: 12/151854   Filing Date: 12/May/2008

Abstract:

Dental compositions comprising a polymerizable compound, filler system of nanometer-sized silica particles, and polymerization system capable of being activated by light are provided. The compositions further contain a solvent such as a mixture of 1-butanol and acetone and may contain water. The nanometer-sized silica particles, having an average particle size of about 1 nm to about 100 nm, are uniformly dispersed within the resin. The compositions can be applied as a polish, sealant, bleach guard, or other coating material to the surfaces of dental restorations and teeth. Self-etching and non-self-etching compositions are provided. The cured coating forms a protective, durable film that enhances the shine and luster of the restorations and teeth.

Priority: US20070928766P Applic. Date: 2007-05-11

Inventor: HUO XIN [US]; O'CONNOR MICHAEL [US]; SIZE ROBERT [US]


Application No.: US20090048149A1  Published: 19/Feb/2009

Title: Antagonists of the bradykinin B1 receptor

Applicant/Assignee: AMGEN INC

Application No.: 12/082395   Filing Date: 09/Apr/2008

Abstract:

The present invention relates to a method of treating, preventing, or ameliorating a disease or condition associated with or mediated by B1 activity that involves administering a composition of matter containing bradykinin B1 receptor antagonist peptides conjugated to a multivalent vehicle, including peptides conjugated to multivalent PEG. The method can be used therapeutically or prophylactically against diseases or conditions, such as inflammation or pain, linked to the bradykinin B1 receptor.

Priority: US2004-972236 Applic. Date: 2004-10-21; US20030513913P Applic. Date: 2003-10-22; US20040538929P Applic. Date: 2004-01-24

Inventor: NG GORDON [US]; LI YUE-SHENG [US]; GEGG COLIN V [US]; ASKEW JR BENNY C [US]; STORZ THOMAS [US]; LU YUELIE [US]; D AMICO DERIN C [US]; JAROSINSKI MARK A [US]; LIU CHUAN-FA [US]; HUANG QI [US]


Application No.: US20090048164A1  Published: 19/Feb/2009

Title: THERAPEUTIC PRO-APOPTOTIC BH3-LIKE MOLECULES AND METHODS FOR GENERATING AND/OR SELECTING THE SAME

Applicant/Assignee: THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH

Application No.: 11/993829   Filing Date: 23/Jun/2006

Abstract:

The present invention relates generally to therapeutic molecules which are useful for modulating apoptosis in a target cell or cell population. More particularly, the present invention provides therapeutic agents which inhibit pro-survival molecules and which are capable of inducing or facilitating apoptosis of a target cell or cell population such as cancer cells. The present invention further provides methods for generating or selecting the therapeutic molecules and pharmaceutical compositions comprising the therapeutic molecules.

Priority: US20050693644P Applic. Date: 2005-06-24; WO2006AU00888 Applic. Date: 2006-06-23

Inventor: COLMAN PETER MALCOLM [AU]; HUANG DAVID CHING SIANG [AU]; LEE ERINNA FAITH [AU]; FAIRLIE WALTER DOUGLAS [AU]


Application No.: US20090048275A1  Published: 19/Feb/2009

Title: SOLID FORMS COMPRISING 4-[9-(TETRAHYDRO-FURAN-3-YL)-8-(2,4,6-TRIFLUORO-PHENYLAMINO)-9H-PURIN-2-YLAMINO]-CYCLOHEXAN-1-OL, COMPOSITIONS THEREOF, AND USES THEREWITH

Applicant/Assignee:

Application No.: 12/200146   Filing Date: 28/Aug/2008

Abstract:

Solid forms comprising 4-[9-(tetrahydro-furan-3-yl)-8-(2,4,6-trifluoro-phenylamino)-9H-purin-2-ylamino]-cyclohexan-1-ol, compositions comprising the solid forms, methods of making the solid forms and methods of their use for the treatment of various diseases and/or disorders are disclosed.

Priority: US2007-977759 Applic. Date: 2007-10-26; US20060854757P Applic. Date: 2006-10-27

Inventor: BEAUCHAMPS MARIE G [US]; CAMERON LOUISE MICHELLE [US]; HILGRAF ROBERT [US]; KOTHARE MOHIT ATUL [US]; SAINDANE MANOHAR T [US]; XU JEAN [US]


Application No.: US20090048324A1  Published: 19/Feb/2009

Title: ALTERNATE MORPHEEIN FORMS OF ALLOSTERIC PROTEINS AS A TARGET FOR THE DEVELOPMENT OF BIOACTIVE MOLECULES

Applicant/Assignee: FOX CHASE CANCER CENTER

Application No.: 12/142435   Filing Date: 19/Jun/2008

Abstract:

A composition having an agent adapted to affect a multimeric protein by binding to a binding site of the multimeric protein and thereby affecting an equilibrium of units, wherein the multimeric protein has an assembly having a plurality of said units, wherein each of the units has a first complementary surface and a second complementary surface and wherein the first complementary surface of one unit is associated with the second complementary surface of another unit, provided that the assembly is at least one of different quaternary isoforms on a condition that in the multimeric protein (1) a structure of each of the units determines a structure of the different quaternary isoforms, (2) the units are in the equilibrium and (3) the structure of the different quaternary isoforms influences a function of the multimeric protein.

Priority: US2006-327762 Applic. Date: 2006-01-06; WO2004US21722 Applic. Date: 2004-07-07; US20030485253P Applic. Date: 2003-07-07; US20040577312P Applic. Date: 2004-06-04; US20050690649P Applic. Date: 2005-06-15

Inventor: JAFFE EILEEN K [US]


Application No.: US20090048341A1  Published: 19/Feb/2009

Title: Tranexamic acid formulations

Applicant/Assignee: XANODYNE PHARMACEUTICALS, INC

Application No.: 12/228489   Filing Date: 13/Aug/2008

Abstract:

Disclosed are modified release oral tranexamic acid formulations and methods of treatment therewith.

Priority: US2005-072194 Applic. Date: 2005-03-04; US20040550113P Applic. Date: 2004-03-04; US20040592885P Applic. Date: 2004-07-30

Inventor: MOORE KEITH A [US]; HEASLEY RALPH A [US]; GREIWE JEFFREY S [US]


Application No.: US20090048367A1  Published: 19/Feb/2009

Title: Dental adhesive

Applicant/Assignee:

Application No.: 12/148572   Filing Date: 21/Apr/2008

Abstract:

Non-aqueous dental adhesive comprising a mixture containing (i) one or more polymerizable monomers optionally containing an acidic group, (ii) a polymerization initiator, and (iii) a thermal polymerization inhibitor of the following formula (I): wherein R'1 represents a hydrogen atom, or a saturated hydrocarbon group having 1 to 18 carbon atoms. R'2, which may be the same or different if more than one R'2 is present, independently represent a saturated hydrocarbon group having 1 to 18 carbon atoms, and c represents an integer of from 1 to 4, and (iv) optionally an organic solvent.

Priority: WO2006EP10051 Applic. Date: 2006-10-18; US2004-493721 Applic. Date: 2004-04-26

Inventor: KLEE JOACHIM E [DE]; LEHMAN UWE [DE]


Application No.: US20090048433A1  Published: 19/Feb/2009

Title: Scalable Process for Protein Purification

Applicant/Assignee: CYTOS BIOTECHNOLOGY AG

Application No.: 11/922591   Filing Date: 20/Jun/2006

Abstract:

The invention provides a process for the purification recombinantly expressed, self-assembled VLP from the homogenate of a bacterial host, wherein the process can be scaled up to a commercial production scale in a cost effective manner. The process comprises a first chromatography using an anion exchange matrix, a second chromatography using hydroxyapatite and, optionally, a size exclusion chromatography. VLP preparations obtained by the process of the invention are essentially free of endotoxin contaminations.

Priority: EP20050105513 Applic. Date: 2005-06-21; WO2006EP63373 Applic. Date: 2006-06-20

Inventor: RICHTER SUSANNE [CH]; TOPELL SIMON [CH]


Application No.: US20090050512A1  Published: 26/Feb/2009

Title: One-way valve with flapper concept for vacuum bag

Applicant/Assignee:

Application No.: 12/075755   Filing Date: 13/Mar/2008

Abstract:

A one-way valve allows air to be drawn from a collapsible, flexible, airtight bag using a vacuum source. When the vacuum source is removed, the one-way valve prevents air from reentering the bag. The valve assembly comprises: a valve base comprising an opening, a seat disposed along a periphery of the opening, a flange surrounding the seat, and first and second pivot supports

a flapper comprising a diaphragm that is deformable and overlies the opening

and a cap pivotably supported by the first and second pivot supports for pivoting between first and second angular positions, the cap comprising at least one vent hole. The cap maintains the diaphragm in contact with the seat along an entire perimeter of the seat when the cap is in the first angular position and does not maintain the diaphragm in contact with the seat along its entire perimeter when the cap is in the second angular position.

Priority: US20070966061P Applic. Date: 2007-08-24

Inventor: PHAM LINH [US]


Application No.: US20090053144A1  Published: 26/Feb/2009

Title: REDUCTION IN BACTERIAL COLONIZATION BY ADMINISTERING BACTERIOPHAGE COMPOSITIONS

Applicant/Assignee: INTRALYTIX, INC

Application No.: 12/264582   Filing Date: 04/Nov/2008

Abstract:

The present invention provides a method for reducing the risk of bacterial infection or sepsis in a susceptible patient by treating the susceptible patient with a pharmaceutical composition containing bacteriophage of one or more strains which produce lytic infections in pathogenic bacteria. Preferably, treatment of the patient reduces the level of colonization with pathogenic bacteria susceptible to the bacteriophage by at least one log. In a typical embodiment, the susceptible patient is an immunocompromised patient selected from the group consisting of leukemia patients, lymphoma patients, carcinoma patients, sarcoma patients, allogeneic transplant patients, congenital or acquired immunodeficiency patients, cystic fibrosis patients, and AIDS patients. In a preferred mode, the patients treated by this method are colonized with the pathogenic bacteria subject to infection by said bacteriophage.

Priority: US2003-724900 Applic. Date: 2003-12-02; US2001-757685 Applic. Date: 2001-01-11; US20000175377P Applic. Date: 2000-01-11; US20000205240P Applic. Date: 2000-05-19; US20000175416P Applic. Date: 2000-01-11; US20000175415P Applic. Date: 2000-01-11

Inventor: MORRIS J GLENN [US]; SULAKVELIDZE ALEXANDER [US]; ALAVIDZE ZEMPHIRA [GE]; PASTERNACK GARY R [US]; BROWN TORREY C [US]


Application No.: US20090053147A1  Published: 26/Feb/2009

Title: Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules

Applicant/Assignee:

Application No.: 12/082389   Filing Date: 09/Apr/2008

Abstract:

Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines.

Priority: US2007-706088 Applic. Date: 2007-02-13; US2003-658834 Applic. Date: 2003-09-08; US20030457135P Applic. Date: 2003-03-21; US20020409898P Applic. Date: 2002-09-09

Inventor: GANTIER RENE [FR]; VEGA MANUEL [FR]; DRITTANTI LILA [FR]; GUYON THIERRY [FR]


Application No.: US20090053151A1  Published: 26/Feb/2009

Title: Antibacterial peptides and analogues thereof

Applicant/Assignee:

Application No.: 11/632449   Filing Date: 13/Jul/2005

Abstract:

Antibacterial peptides and their multimeric analogues, with a wide range of action and low haemolytic activity are described. In particular, the peptide molecules exhibit a high antimicrobial activity against numerous bacterial species, with reduced cytotoxicity and a low haemolysis rate. The molecules of the invention are advantageously usable as therapeutic agents and coadjutants against infections caused by strains that are resistant to common antibiotics.

Priority: IT2004RM00349 Applic. Date: 2004-07-13; WO2005IT00397 Applic. Date: 2005-07-13

Inventor: BRACCI LUISA [IT]; GIULIANI ANDREA [IT]; PINI ALESSANDRO [IT]; NERI PAOLO [IT]


Application No.: US20090053247A1  Published: 26/Feb/2009

Title: BIOLOGICAL MATERIALS AND USES THEREOF

Applicant/Assignee: PHOTOBIOTICS LIMITED

Application No.: 12/089406   Filing Date: 06/Oct/2006

Abstract:

Priority: GB20050020436 Applic. Date: 2005-10-07; WO2006GB03733 Applic. Date: 2006-10-06

Inventor: DEONARAIN MAHENDRA [GB]; YAHIOGLU GOKHAN [GB]; BHATTI MANPREET [GB]


Application No.: US20090053267A1  Published: 26/Feb/2009

Title: DENTIFRICE COMPOSITION CONTAINING SILICONE OIL BEADS

Applicant/Assignee:

Application No.: 11/841183   Filing Date: 20/Aug/2007

Abstract:

Dentifrice composition and method of using such dentifrice composition to ameliorate dry mouth, where the dentifrice composition includes an orally acceptable vehicle having distributed therein silicone oil beads, and wherein the dentifrice composition has a viscosity of at least about 20,000 centipoise.

Priority:

Inventor: DEPIERRO KAREN [US]; SANTARPIA III RALPH PETER [US]; CURTIS JOHN PIERRE [US]; NILES HOLLANDRA [US]; DARCY-SIEGEL JOANN [US]; BLACKWELL BERNIE L [US]


Application No.: US20090053311A1  Published: 26/Feb/2009

Title: Pharmaceutical Compositions for Treating or Preventing Bone Conditions

Applicant/Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Application No.: 11/884525   Filing Date: 16/Feb/2006

Abstract:

Provided herein is a pharmaceutical composition for treating, preventing or ameliorating a bone or cartilage condition and methods of making and using the same.

Priority: US20050653722P Applic. Date: 2005-02-16; WO2006US05473 Applic. Date: 2006-02-16

Inventor: SOO CHIA [US]; TING KANG [US]; KURODA SHUNICHI [JP]; WU BEN [US]


Application No.: US20090053672A1  Published: 26/Feb/2009

Title: Variable temperature dental irrigator

Applicant/Assignee:

Application No.: 11/894019   Filing Date: 20/Aug/2007

Abstract:

Variable temperature (operator controlled) dental irrigator constructed of three pieces of stainless steel or high-grade aluminum housing two water supply tubes (cold and hot) sealed with O-Rings. The calibrated temperature control valve located on the discharge end of the dental irrigator allows the user (dentist or technician) to adjust the water spray from the irrigator to suit the patient's comfort desire. An additional feature of the irrigator is the interchangeable discharge jets (tips) that may be screwed on/off the main irrigator body for sterilization.

Priority:

Inventor: CORNELIUS STEVEN LOUIS [US]


Application No.: US20090054377A1  Published: 26/Feb/2009

Title: COMPOSITIONS AND METHODS FOR SMOKING CESSATION

Applicant/Assignee: MODUS BIOLOGICAL MEMBRANES LTD

Application No.: 11/658665   Filing Date: 25/Jul/2005

Abstract:

The invention discloses a method and a composition for smoking cessation or for promoting smoking cessation in individual smokers. The compositions described contain phosphatidic acid as the active ingredient.

Priority: US20040591261P Applic. Date: 2004-07-27; US20050659095P Applic. Date: 2005-03-08; WO2005IL00789 Applic. Date: 2005-07-25

Inventor: SHENFELD AVNER [IL]


Application No.: US20090054528A1  Published: 26/Feb/2009

Title: Bridged polycyclic compound based compositions for coating oral surfaces in pets

Applicant/Assignee:

Application No.: 12/228262   Filing Date: 11/Aug/2008

Abstract:

A pharmaceutically active agent, a pharmaceutically active agent carrier and method of use thereof are described. In some embodiments, a system may include a composition. The composition may include one or more bridged polycyclic compounds. At least one of the bridged polycyclic compounds may include at least two cyclic groups, and at least two pharmaceutically active agents may be associated with the bridged polycyclic compound. In some embodiments, one or more bridged polycyclic compounds may be applied to an oral surface of an animal (e.g., canine, feline) such that an oral malady may be inhibited and/or ameliorated.

Priority: US20070964312P Applic. Date: 2007-08-10; US20070965154P Applic. Date: 2007-08-17; US20080029332P Applic. Date: 2008-02-16; US20080074494P Applic. Date: 2008-06-20

Inventor: WHITEFORD JEFFERY A [US]


Application No.: US20090056068A1  Published: 05/Mar/2009

Title: UPRIGHT VACUUM CLEANER

Applicant/Assignee: MIELE & CIE. KG

Application No.: 12/199316   Filing Date: 27/Aug/2008

Abstract:

An upright vacuum cleaner for cleaning a surface. The vacuum cleaner includes an upper body having a dust collection container, a base unit having a suction mouth and a carriage for moving the base unit on the surface. A motor-fan unit is included and is disposed outside the upper body. The motor-fan unit is operable to create a partial vacuum on the surface. A combined coaxial conduit is disposed in a transition region to the upper body. The combined coaxial conduit includes a first air conduit from the suction mouth to the upper body and a second air conduit from the upper body to the motor-fan unit.

Priority: DE200710040949 Applic. Date: 2007-08-30

Inventor: ISERINGHAUSEN TINA [DE]; MERSMANN UDO [DE]


Application No.: US20090056709A1  Published: 05/Mar/2009

Title: Method and apparatus for alleviating nasal congestion

Applicant/Assignee:

Application No.: 11/896716   Filing Date: 05/Sep/2007

Abstract:

The present invention relates generally to the field of treatments for nasal congestion, and in particular, to a method and apparatus for alleviating nasal congestion in a patient by mechanically stimulating the sneezing reflex in the patient to urge drainage of the nasal passageways. The method includes inserting an instrument having a work tip portion provided with at least one filament into the nostril of the patient. The nasal mucosa of the patient is then probed with the at least one filament to stimulate in the patient the sneeze reflex. This probing action causes the patient to sneeze. With the patient's mouth closed, the sneeze urges at least one of mucus, fluid and debris in the nasal passages of the patient to be forcibly expelled through the nostrils of the patient thereby draining the nasal cavity of the patient. The instrument used in the performance of this method includes a handle portion upon which the work tip portion is carried. The handle portion may be integrally formed with the work tip portion or releasably attachable thereto. The instrument is further provided with a physical stop associated with one of the work tip portion and the handle portion to prevent injury resulting from the working tip portion being inserted too deeply into the nasal passages of the patient.

Priority:

Inventor: WORSOFF MAYA [CA]


Application No.: US20090056724A1  Published: 05/Mar/2009

Title: SLEEP APPLIANCE

Applicant/Assignee:

Application No.: 12/252848   Filing Date: 16/Oct/2008

Abstract:

A dental oral appliance for use with patients who suffer with sleep disorders, to reduce or eliminate snoring and to open the airway for a sleeping individual who suffers with obstructive sleep apnea. The appliance covers the inside (lingual) of the upper teeth and has an open palate. Retention for the appliance is provided by either clasps placed over the upper right and left molars and a retainer in the anterior area or by an occlusal coverage of the upper teeth. A raised incisor ramp that extends from the incisal tip (biting edge) of the incisors toward the lingual, or posterior raised ramps, separate the posterior teeth to reduce spasm on the temporalis muscle. A transverse, transpalatal member, which extends from the inside (lingual) of the upper right molars to the inside of the upper left molars, covers the tongue, preventing it from moving upward or backward during sleep, opening the airway.

Priority: US2005-165641 Applic. Date: 2005-06-23

Inventor: KEROPIAN BRYAN [US]


Application No.: US20090056725A1  Published: 05/Mar/2009

Title: Protective guards and method of using same

Applicant/Assignee:

Application No.: 11/897278   Filing Date: 29/Aug/2007

Abstract:

A method and apparatus for protecting a user's mouth from discomfort caused by installed dental brackets of the character having a plurality of bracket members attached to the teeth of the user with cooperating wire support members attached to the brackets. The apparatus includes a plurality of uniquely configured protective guards that can be quickly and easily connected to and removed from the bracket members of the installed dental bracket. The protective guards are preferably constructed from a soft, stretchable material and comprise an end guard, a side guard, a corner guard and a front guard, each of which can be readily, removably attached to the dental bracket at selected areas to protect the inside of the user's mouth from injury.

Priority:

Inventor: ZAND FARNAZ [US]


Application No.: US20090057338A1  Published: 05/Mar/2009

Title: DISPENSING CARTRIDGE

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 12/262961   Filing Date: 31/Oct/2008

Abstract:

A dispensing cartridge, particularly for dental impression materials, formed from a plastic material having at least one inlet and at least one outlet, and including a metal reinforcement tube.

Priority: EP20030013831 Applic. Date: 2003-06-18; US2004-867060 Applic. Date: 2004-06-14

Inventor: KNEE MICHAEL [DE]; MUELLER DIRK [DE]; WAGNER INGO W [DE]


Application No.: US20090060799A1  Published: 05/Mar/2009

Title: Adjustable tabletop air freshener

Applicant/Assignee:

Application No.: 11/785053   Filing Date: 13/Apr/2007

Abstract:

We describe an adjustable table-top air freshener composed of a case that comprises an internally hollow body, provided with four pairs of slots arranged in couples around the perimeter of its lateral wall, and a cover which presents through-holes in its surface. The case body is designed to hold four absorbent pieces of aromatizing product, executed in twos with a three-point star and circular configuration with alternately sunken and protruding portions on its perimeter edge, of a diameter slightly smaller than the inside diameter of the case body and stacked alternately in the interior of the case body, with a star-shaped piece occupying the bottom position. The cover presents the formation of ribs of a predetermined height protruding from its inner face, interposed respectively between successive openings, which assure the separation between said cover and the absorbent piece located in the upper position.

Priority: ES20060001877U Applic. Date: 2006-08-09

Inventor: TORRES DAVID FERNANDEZ [ES]


Application No.: US20090060850A1  Published: 05/Mar/2009

Title: ERICACEA EXTRACTS FOR COMBATING SKIN AGING

Applicant/Assignee: L'OREAL

Application No.: 12/270161   Filing Date: 13/Nov/2008

Abstract:

Extracts of plants of the Ericacea family are administered to individuals to combat the signs of aging of the skin, e.g., wrinkles and fine lines, for example by inhibiting the expression of metalloproteases, by inhibiting collagen degradation, or by inhibiting UV-induced skin degradation.

Priority: FR20000012737 Applic. Date: 2000-10-05; US2001-970797 Applic. Date: 2001-10-05

Inventor: FAGOT DOMINIQUE [FR]


Application No.: US20090062253A1  Published: 05/Mar/2009

Title: HETEROCYCLODIAZEPINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE

Applicant/Assignee: KALYPSYS, INC

Application No.: 12/200554   Filing Date: 28/Aug/2008

Abstract:

The present invention relates to compounds and methods useful as modulators of CB2 for the treatment or prevention of disease states including, but not limited to pain, autoimmune disease, malabsorption syndrome, pulmonary disease, osteoporosis, muscle spasm in cancer, neuromuscular disorder, and atherosclerosis progression.

Priority: US20070969174P Applic. Date: 2007-08-31

Inventor: GAHMAN TIMOTHY C [US]; ZHAO CUNXIANG [US]; LANG HENGYUAN [US]; MASSARI MARK EBEN [US]


Application No.: US20090062345A1  Published: 05/Mar/2009

Title: AMIDE DERIVATIVES AS TRPV1 ANTAGONISTS

Applicant/Assignee: ABBOTT LABORATORIES

Application No.: 12/188323   Filing Date: 08/Aug/2008

Abstract:

The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, and R3, are defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

Priority: US20070954945P Applic. Date: 2007-08-09

Inventor: VASUDEVAN ANIL [US]; BROWN BRIAN S [US]; DAANEN JEROME F [US]; GOMTSYAN ARTHUR R [US]; JINKERSON TAMMIE K [US]; KEDDY RYAN G [US]; KORT MICHAEL E [US]; KYM PHILIP R [US]; MATULENKO MARK A [US]


Application No.: US20090062401A1  Published: 05/Mar/2009

Title: DECALINE-DERIVED COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS

Applicant/Assignee: UNIVERSITAT DORTMUND MAX-PLANCK-GESELLSCHAFT ZUR FODERUNG DER WISSENSCHAFTEN E.V UNIVERSITAT BERN

Application No.: 11/813129   Filing Date: 28/Dec/2005

Abstract:

The present invention relates to compounds having a decaline scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable carrier, excipient and/or diluents. Said decaline-derived compounds can be used for prophylaxsis and/or treatment of diabetes mellitus type I, diabetes mellitus type II, tuberculosis and other infectious diseases, proliferative diseases, cancer, neurodegenerative diseases, obesity, cognitive dysfunctions and metabolic syndromes.

Priority: EP20040031076 Applic. Date: 2004-12-31; WO2005EP14100 Applic. Date: 2005-12-28

Inventor: ODERMATT ALEX [CH]; WALDMANN HERBERT [DE]; SCHECK MICHAEL [DE]; KOCH MARCUS A [DE]


Application No.: US20090062500A1  Published: 05/Mar/2009

Title: Process for preparing low-viscosity allophanates containing actinically curable groups

Applicant/Assignee:

Application No.: 12/229116   Filing Date: 20/Aug/2008

Abstract:

The present invention relates to a process for preparing low-viscosity reaction products of polyisocyanates containing activated, ethylenically unsaturated groups which react, with polymerization, on exposure to actinic radiation.

Priority: DE200710040239 Applic. Date: 2007-08-25

Inventor: LUDEWIG MICHAEL [DE]; FISCHER WOLFGANG [DE]; KUCZEWSKI HELMUT [DE]


Application No.: US20090062677A1  Published: 05/Mar/2009

Title: Method of Recording and Saving of Human Soul for Human Immortality and Installation for it

Applicant/Assignee:

Application No.: 11/613380   Filing Date: 20/Dec/2006

Abstract:

The inventor shows that a human soul is only the information in human brain. He offers a method for re-writing the human brain on electronic chips. This method allows for the modeling of a human soul in order to achieve man immortality. This method does not damage the brain but works to extend and enhance it. This method of writing and saving of Human Soul includes: writing of views which person see in during his life by a micro video recorder to a portable memory

writing of sounds which person speaks and hears by microphone

writing of person physical conditions by micro sensors

writing of time and dates

writing of person body position and so on. An Installation utilized the Method is comprising devices: micro video camera located at man head, microphone, computer (chip) for data processing, portable memory located at an person body and connected to the portable memory

portable recorder for writing of life film located at the man body and connected to the computer and to the portable memory

micro sensors for writing of person physical and environment conditions

a clock for writing of time, the micro sensors for writing of men body positions

navigation system, long time memory high capability storage and so on.

Priority:

Inventor: BOLONKIN ALEXANDER ALEXANDROVICH [US]


Application No.: US20090064860A1  Published: 12/Mar/2009

Title: Z-filter media with reverse-flow cleaning systems and methods

Applicant/Assignee: DONALDSON COMPANY, INC

Application No.: 12/074157   Filing Date: 29/Feb/2008

Abstract:

A method for cleaning a filter having Z-media includes providing a filter having Z-media and cleaning the media construction by directing a pulse of compressed gas into the media construction through the downstream flow face. Filter elements useable with such methods include elements made of Z-media. An example system utilizing the method includes a gas turbine air intake system.

Priority: US2006-331392 Applic. Date: 2006-01-12; US2003-731564 Applic. Date: 2003-12-08; US20020432923P Applic. Date: 2002-12-11

Inventor: SPORRE TIMOTHY D [US]; ROTHMAN JIM C [US]; HANDLEY MICHAEL W [US]; RAETHER THOMAS D [US]


Application No.: US20090065600A1  Published: 12/Mar/2009

Title: Spray Device Having a Piezoelectric Element, and Use Thereof in Cosmetology and Perfumery

Applicant/Assignee: LVMH RECHERCHE

Application No.: 12/293053   Filing Date: 13/Mar/2007

Abstract:

Spray device comprising a piezoelectric element, a sonotrode having a base coupled to the piezoelectric element, and a tube extending as far as a horn, a drive circuit for vibrating the piezoelectric element, and a feed device for bringing the product to be sprayed up to the front face of the horn. The sonotrode mainly vibrates in a mode parallel to the tube, the horn being dimensioned so as not to flex along the longitudinal axis, without flexing when the drive circuit vibrates the piezoelectric element. This spray device is applicable in cosmetology and in perfumery.

Priority: FR20060002281 Applic. Date: 2006-03-15; WO2007FR00433 Applic. Date: 2007-03-13

Inventor: TRANCHANT JEAN-FRANCOIS [FR]; RICHER SYLVIE [FR]; SAUZADE JEAN-DENIS [FR]


Application No.: US20090067695A1  Published: 12/Mar/2009

Title: IMAGE PROCESSING SYSTEM WHICH CALCULATES AND DISPLAYS COLOR GRADE DATA AND DISPLAY IMAGE DATA

Applicant/Assignee: OLYMPUS OPTICAL CO., LTD

Application No.: 12/264056   Filing Date: 03/Nov/2008

Abstract:

An image processing system is used for dentistry. Upon creating a false tooth of a patient (59), a plurality of illuminating light of LEDs with different wavelengths emit light and a photographing apparatus (1A) photographs a tooth portion of the patient (59), thereby obtaining image data. The image data is sent to a dentistry filing system (2A) serving as a processing apparatus, and color reproducing data is obtained by calculation. The color reproducing data is sent to a dentistry factory (55) via a public line. Data is searched from a database (56) for calculating a ceramic compounding ratio, compound data of the ceramic false tooth is obtained, matching the color of the tooth portion of the patient (59), and the false tooth approximate to the tooth color of the patient (59) is created.

Priority: JP20020218864 Applic. Date: 2002-07-26; US2005-521779 Applic. Date: 2005-01-21; WO2003JP09381 Applic. Date: 2003-07-24

Inventor: KOMIYA YASUHIRO [JP]; WADA TORU [JP]; KONNO OSAMU [JP]; AJITO TAKEYUKI [JP]; NAKAMURA TOMOYUKI [JP]


Application No.: US20090068121A1  Published: 12/Mar/2009

Title: LANTIBIOTICS AND USES THEREOF

Applicant/Assignee:

Application No.: 12/176124   Filing Date: 18/Jul/2008

Abstract:

The present invention provides isolated lantibiotics that inhibit Gram negative and Gram positive microbes. The lantibiotic includes an amino acid sequence, wherein the amino acid sequence of the compound and the amino acid sequence of SEQ ID NO:21 or SEQ ID NO:22 have at least 80% identity. The lantibiotics have the characteristic of inhibiting growth of a Gram negative microbe in conditions that do not damage the outer membrane of the Gram negative microbe. The present invention also provides methods for making and using the lantibiotics.

Priority: US20070961374P Applic. Date: 2007-07-20

Inventor: O'SULLIVAN DANIEL J [US]; LEE JU-HOON [US]


Application No.: US20090068122A1  Published: 12/Mar/2009

Title: Dentifrice Compositions for Treating Xerostomia

Applicant/Assignee:

Application No.: 11/850955   Filing Date: 06/Sep/2007

Abstract:

This invention encompasses an oral composition for treating or preventing dry mouth with following benefits: antibacterial/anti-fungal efficacy, low irritancy, and moisture retention. The compositions can be a toothpaste, a mouth rinse or a spray and include one or more non-ionic surfactants, as foaming agents, one or more broad spectrum anti-microbial ingredient, such as chlorhexidine and cetylpyridinium chloride, and one or more oral surface adhesive polysaccharides that can encage cationic actives to help the deposition and retention of the agents onto oral surfaces and thus provide antimicrobial efficacy.

Priority:

Inventor: PILCH SHIRA [US]; MASTERS JAMES GERARD [US]


Application No.: US20090068123A1  Published: 12/Mar/2009

Title: FLUORINE ION-RELEASABLE COMPOSITION FOR DENTAL PURPOSES

Applicant/Assignee: KURARAY MEDICAL INC

Application No.: 11/910319   Filing Date: 30/Mar/2006

Abstract:

The invention provides a fluoride ion releasing dental composition including an inorganic powder (a)

a fluoride ion releasing material (b)

a monomer (c)

and a polymerization initiator (d), in which the inorganic powder (a) is made of composite particles in which a layer of polysiloxane is formed on surfaces of substrate particles made of an inorganic material, and the fluoride ion releasing material (b) is at least one fluoride ion releasing material selected from the group consisting of ammonium fluoride, ammonium hydrogen fluoride, a metal fluoride, a polymer including, as a constitutional unit, a vinyl monomer having an acid fluoride group and a fluorine-containing phosphazene monomer. Since the fluoride ion releasing dental composition of this invention provides dentine with a high cariostatic property over a long period of time by gradually releasing fluoride ions, it is suitably used as a dental adhesive material, a dental filling material, a dental resin used for forming an abutment, a pit and fissure sealant, a dental coating material (manicure), a dental cement and so on.

Priority: JP20050097353 Applic. Date: 2005-03-30; WO2006JP306689 Applic. Date: 2006-03-30

Inventor: TAKEI MITSURU [JP]; KITA HIROTAKA [JP]; OHARA YASUJIRO [JP]


Application No.: US20090068125A1  Published: 12/Mar/2009

Title: TREATMENT FOR MUCOSITIS

Applicant/Assignee: HEPTAGEN LTD

Application No.: 11/814796   Filing Date: 25/Jan/2006

Abstract:

This invention relates to a medicament for protecting human mucosal cells from chemotherapy or radiotherapy induced cell death using formulations comprising adenosine or adenosine analogues as a reversible inhibitor of epithelial cell proliferation. The invention also relates to formulations containing adenosine for the prevention of or reduction in mucositis symptoms.

Priority: GB20050001476 Applic. Date: 2005-01-25; WO2006GB00241 Applic. Date: 2006-01-25

Inventor: EDWARDS RICHARD MARK [GB]; CLEMENTS JOHN MARTIN [GB]


Application No.: US20090068259A1  Published: 12/Mar/2009

Title: Controlled Surface Gelling of Mucoadhesive Polymers on Oral Mucosa

Applicant/Assignee:

Application No.: 11/850886   Filing Date: 06/Sep/2007

Abstract:

The present invention relates to an oral composition and method for alleviating the symptoms associated with xerostomia using encapsulated cation-releasing compounds formulated either intimately together or in separate compartments in a composition containing cation-sensitive mucoadhesive polymers.

Priority:

Inventor: PILCH SHIRA [US]; MASTERS JAMES GERARD [US]; DILLON RENSL [US]; VISCIO DAVID BENEDICT [US]


Application No.: US20090068287A1  Published: 12/Mar/2009

Title: Novel topical formulations of flucytosine and uses thereof

Applicant/Assignee:

Application No.: 12/229548   Filing Date: 25/Aug/2008

Abstract:

The invention relates to topical formulations and methods of use of flucytosine which demonstrate a clear advantage over currently available therapeutic regimens for the treatment and maintenance of fungal infections, particularly vulvovaginal candidiasis. The invention provides compositions which solve the long-standing need for antimicrobial agents which treat effectively resistant strains of Candida spp., especially C. albicans, C. glabrata, and C. tropicalis, and which pose limited risk of side effects, adverse reactions, or the development of resistant pathogens. The invention provides novel topical formulations of flucytosine designed to allow the active drug to act at the local application area, but which inhibit or moderate transdermal or transmucosal absorption of the drug, thus limiting systemic exposure.

Priority: US20070993635P Applic. Date: 2007-09-12; US20070009626P Applic. Date: 2007-12-31; US20080137349P Applic. Date: 2008-07-29

Inventor: WELSH SUSAN [US]; WOOD RICHARD D [US]


Application No.: US20090068613A1  Published: 12/Mar/2009

Title: PORTABLE COLOR CORRECTED OVER HEAD DENTAL LIGHT TO MATCH SHADES OF TEETH WITH TRUE CHROMATIC EFFICIENCY AND TO ACCELERATE TOOTH WHITENING

Applicant/Assignee:

Application No.: 11/852290   Filing Date: 08/Sep/2007

Abstract:

A portable color corrected light for the correct matching of tooth shades and acceleration of tooth whitening has been developed. In order to accurately match the tint and hue (true color) of teeth, the device provides 5500 to 6500 Kelvin, ambient-independent light with the ability to block or overwhelm ambient light to get a precise "color" reading of that tooth. The same light can accelerate the tooth whitening process with the addition of photo-accelerators to increase the decomposition of H2O2 or other peroxide whitening material. In addition, the same light can also serve as a dental operatory light which provides a closer to daylight illumination than conventional halogen dental lights.

Priority:

Inventor: WANG DANIEL [US]; CREAMER ALAN AUSTIN [US]


Application No.: US20090068619A1  Published: 12/Mar/2009

Title: COMPOSITION CONTAINING AZIRIDINO GROUPS AND USE THEREOF

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 12/278983   Filing Date: 08/Feb/2007

Abstract:

The invention relates to a composition comprising a prepolymer as component (A), wherein the prepolymer comprises aziridino groups and is characterized by an equivalent weight EW1, a crosslinker as component (B), wherein the crosslinker has a structure being different from the structure of the prepolymer and comprises aziridino groups and is characterized by an equivalent weight EW2, an initiator as component (C) being able to start curing of the composition, optionally filler(s) as component (D) and optionally additive(s) as component (E), wherein equivalent weight is defined as (molecular mass of the molecule)/(number of aziridino groups present in the molecule) and wherein EW1>EW2. The invention also relates to the use of the composition for coating, sealing, moulding, adhering, making impressions, producing a dental material.

Priority: EP20060003085 Applic. Date: 2006-02-15; WO2007US03389 Applic. Date: 2007-02-08

Inventor: KLETTKE THOMAS [DE]; FUEHRER CORNELIA B [DE]; BISSINGER PETER [DE]


Application No.: US20090069426A1  Published: 12/Mar/2009

Title: Methods For Reducing The Amount Of A Proinflammatory Substance In Animal Tissue Or Body Fluid

Applicant/Assignee: HILL'S PET NUTRITION, INC

Application No.: 12/094188   Filing Date: 17/Nov/2006

Abstract:

A method for reducing the amount of a proinflammatory substance present at an elevated level in animal tissue or body fluid by orally administering to the animal a proinflammatory substance reducing amount of a composition comprising at least one omega-3 fatty acid. The method is useful for reducing inflammation caused by elevated levels of proinflammatory substances including inflammation associated with an oral condition.

Priority: US20050738128P Applic. Date: 2005-11-18; WO2006US61037 Applic. Date: 2006-11-17

Inventor: SCHERL DALE SCOTT [US]; LOGAN ELLEN IRENE [US]; GROSS KATHY LYNN [US]


Application No.: US20090071368A1  Published: 19/Mar/2009

Title: Process for the dispersion of fine-particle inorganic powders in liquid media, with use of reactive siloxanes

Applicant/Assignee: BUHLER PARTEC GMBH

Application No.: 12/211989   Filing Date: 17/Sep/2008

Abstract:

The invention relates to a process for the dispersion of fine-particle surface-modified inorganic powders in liquid media, with use of siloxanes. A process for the preparation of a dispersion of inorganic particles in a liquid medium is described, in which inorganic particles which have been surface-modified so that they have at least one organic group on the surface are mixed in a liquid medium with an organosiloxane, where at least one organic group of the organosiloxane corresponds to the at least one organic group on the surface of the inorganic particles.

Priority: DE200710044302 Applic. Date: 2007-09-17

Inventor: STEINGROVER KLAUS [DE]; TABELLION FRANK [DE]; PILOTEK STEFFEN [DE]; KHIM MICHAEL [DE]


Application No.: US20090071415A1  Published: 19/Mar/2009

Title: Veterinary gurney or table incorporating a removable dental tray

Applicant/Assignee:

Application No.: 12/077754   Filing Date: 24/Mar/2008

Abstract:

A veterinary gurney or table having a base frame member supporting a mobility means, an elevation frame member mounted on the base frame, and a table member mounted on the elevation frame, allowing the elevation of the gurney or table to be locked at a selected height, one end of the gurney or table adapted to receive a slidable, securable dental tray for dental treatment of the animal while positioned on the gurney or table.

Priority: US20070919880P Applic. Date: 2007-03-26

Inventor: JEHN FRANK [US]


Application No.: US20090072425A1  Published: 19/Mar/2009

Title: Low-dusting investment composition material

Applicant/Assignee:

Application No.: 12/156937   Filing Date: 03/Jun/2008

Abstract:

A method for manufacturing a heat-resistant mold for manufacturing a dental restoration, wherein a wax model is manufactured in a conventional manner and wherein from a powdered heat-resistant material consisting of powdered particles coated with a hydrophobic material liquid at room temperature, with water or another mixing liquid, a slurry is prepared, wherein the slurry is applied to the wax model, and wherein the wax model covered slurry is subjected to a heating step, wherein the wax is burnt off.

Priority: NL20021020577 Applic. Date: 2002-05-10; WO2003NL00344 Applic. Date: 2003-05-09; US2005-514063 Applic. Date: 2005-10-24

Inventor: BETTMAN MARIJKE [NL]; VAN DER ZEL JOSEPH MARIA [NL]; GRINWIS THEODORUS JACOBUS [NL]


Application No.: US20090074679A1  Published: 19/Mar/2009

Title: TOOTH WHITENING METHODS AND APPARATUSES

Applicant/Assignee:

Application No.: 11/854714   Filing Date: 13/Sep/2007

Abstract:

Some disclosed tooth whitening methods comprise: painting a tooth whitening solution or gel including a bleaching agent onto teeth

and subsequent to the painting, disposing a conforming protective cover over the teeth. In some embodiments, the painting and disposing are performed under the non-interventional guidance of a session guide. In some tooth whitening article of manufacture embodiments, a tooth whitening solution or gel includes a bleaching agent, the tooth whitening solution or gel being configured for paint-on application onto teeth, and conforming protective cover is configured to be conformally disposed over the teeth after painting with the tooth whitening solution or gel. In some embodiments a tooth whitening solution or gel includes a bleaching agent at hydrogen peroxide-equivalent concentration of greater than or about 10 percent and does not include a reactive thickening agent.

Priority:

Inventor: SILVERMAN HARVEY N [US]


Application No.: US20090074680A1  Published: 19/Mar/2009

Title: STATHERIN PEPTIDE AND USE IN MEDICINE

Applicant/Assignee: QUEEN MARY & WESTFIELD COLLEGE

Application No.: 11/909342   Filing Date: 23/Mar/2006

Abstract:

A synthetic statherin peptide of general formula (I) X1X2X3X4X5X6X7X8X9X10X11X12X13X14X15X16X17X18X19X20X21 as defined herein is provided. The peptide finds application in the treatment of dent disease, dry mouth syndrome and in the formulation of pharmaceutical preparation comprising the peptide.

Priority: GB20050005975 Applic. Date: 2005-03-23; WO2006GB01085 Applic. Date: 2006-03-23

Inventor: ANDERSON PAUL [GB]; KOSORIC JELENA [GB]; WILLIAMS RALPH ANTHONY DAVID [GB]; HECTOR MARK P [GB]


Application No.: US20090074736A1  Published: 19/Mar/2009

Title: IMPLANTABLE PREPARATIONS COMPRISING GLOBIN, PROCESS FOR THEIR PRODUCTION, AND USES

Applicant/Assignee:

Application No.: 12/207621   Filing Date: 10/Sep/2008

Abstract:

Preparations comprising, especially, globin that is insoluble at neutral pH, and therefore at physiological pH, in which the globin has been obtained from whole blood by depigmentation in a medium that extracts or dissolves the haem but leaves the globin and the other constituents of proteinic nature in a substantially undissolved state, a process for the production of those preparations, and uses, especially for the filling, healing or regeneration of tissues, especially for chronic wounds and osseous healing or regeneration.

Priority: FR20070057501 Applic. Date: 2007-09-11; US20070971349P Applic. Date: 2007-09-11

Inventor: TAYOT JEAN-LOUIS [FR]; SAPIN FLORENT [FR]; BERNASCONI JEAN [FR]


Application No.: US20090074816A1  Published: 19/Mar/2009

Title: TISSUE TARGETED ANTIGENIC ACTIVATION OF THE IMMUNE RESPONSE TO CANCERS

Applicant/Assignee:

Application No.: 12/234569   Filing Date: 19/Sep/2008

Abstract:

The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The formulations of the invention thereby facilitate activation of a treatment response to a cancer in a particular tissue or organ. The compositions may for example include killed or attenuated microbial pathogens, and may be administered at sites distant from the cancer, for example the skin. In some embodiments, microbial species of endogenous flora that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions. In alternative embodiments, exogenous microbial pathogens that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions. The administration of the immunogenic compositions may be repeated relatively frequently over a relatively long period of time. In embodiments for intradermal or subcutaneous injection, dosages may be adjusted so that injections reproduce a consistent visible delayed inflammatory immune reaction at the successive site or sites of administration.

Priority: US2006-553972 Applic. Date: 2006-10-27; WO2005CA00812 Applic. Date: 2005-05-30; WO2007CA01915 Applic. Date: 2007-10-25; US20040577206P Applic. Date: 2004-06-07

Inventor: GUNN HAROLD DAVID [CA]


Application No.: US20090074833A1  Published: 19/Mar/2009

Title: BRIDGED POLYCYCLIC COMPOUND BASED COMPOSITIONS FOR CONTROLLING BONE RESORPTION

Applicant/Assignee:

Application No.: 12/193529   Filing Date: 18/Aug/2008

Abstract:

A pharmaceutically active agent, a pharmaceutically active agent carrier and method of use thereof are described. In some embodiments, a system may include a composition. The composition may include one or more bridged polycyclic compounds. At least one of the bridged polycyclic compounds may include at least two cyclic groups, and at least two pharmaceutically active agents may be associated with the bridged polycyclic compound. In some embodiments, a composition may be administered to a subject to control bone resorption, inflammation, and/or pain.

Priority: US20070965154P Applic. Date: 2007-08-17; US20080029332P Applic. Date: 2008-02-16; US20080074462P Applic. Date: 2008-06-20

Inventor: WHITEFORD JEFFERY A [US]


Application No.: US20090074919A1  Published: 19/Mar/2009

Title: American school lunch meals

Applicant/Assignee:

Application No.: 11/900445   Filing Date: 13/Sep/2007

Abstract:

A process for designing, and flavoring a shelf stable baked meal, cereal meal, freeze dried meal, chocolate meal, caramel meal, popsicle meal, and ice cream antithesis meal by taking a commercial brand name product and improving it by adding foodstuff nutrients to make it an American meal. When combined they meet the predetermined requirements of the National School Lunch program, the United States Department and the Dash Eating plan food intake requirements as defined in present invention. The said meals takes an existing commercial product, an example is candy bar and adds the necessary foodstuff components to the candy bar such that when combined the final product meets the food intake requirements of said American meal. The method of producing shelf stable various meals comprise using existing known methods and technologies of preparing foodstuff and keeping it fresh and ready to eat until opened.

Priority:

Inventor: SMITH LEON CURTIS [US]


Application No.: US20090075229A1  Published: 19/Mar/2009

Title: PROBES AND BIOFLUIDS FOR TREATING AND REMOVING DEPOSITS FROM TISSUE SURFACES

Applicant/Assignee:

Application No.: 12/234593   Filing Date: 19/Sep/2008

Abstract:

An endodontic probe is used to perform disinfection procedures on target tissues within root canal passages and tubules. The endodontic probe can include an electromagnetic radiation emitting fiber optic tip having a distal end and a radiation emitting region disposed proximally of the distal end. According to one aspect, the endodontic probe can include a porous structure that encompasses a region of the fiber optic tip excluding the radiation emitting region and that is loaded with biologically-active particles, cleaning particles, biologically-active agents, or cleaning agents for delivery from the porous structure onto the target tissues. Another aspect can include provision of the endodontic probe with an adjustable channel-depth indicator, which encompasses a region of the fiber optic tip besides the radiation emitting region and which is movable in proximal and distal directions along a surface of the fiber optic tip to facilitate the provision of depth-of-insertion information to users of the endodontic probe.

Priority: US20070995759P Applic. Date: 2007-09-28; US20070994891P Applic. Date: 2007-09-21; US20070994723P Applic. Date: 2007-09-20; US20070994571P Applic. Date: 2007-09-19

Inventor: RIZOIU IOANA M [US]; JONES JEFFREY W [US]; CHUEH PETER [US]


Application No.: US20090075239A1  Published: 19/Mar/2009

Title: COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 12/275954   Filing Date: 21/Nov/2008

Abstract:

The present invention is directed to compositions containing one or more polymerizable bisphosphonic acids and optionally one or more additional polymerizable components.

Priority: US2003-729497 Applic. Date: 2003-12-05; US20020437106P Applic. Date: 2002-12-30

Inventor: ABUELYAMAN AHMED S [US]


Application No.: US20090075981A1  Published: 19/Mar/2009

Title: INHIBITORS OF p38

Applicant/Assignee: VERTEX PHARMACEUTICALS INCORPORATED

Application No.: 12/184996   Filing Date: 01/Aug/2008

Abstract:

The present invention relates to inhibitors of p38, a mammalian protein kinase involved cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.

Priority: US2006-430512 Applic. Date: 2006-05-08; US2003-638126 Applic. Date: 2003-08-08; US2000-746722 Applic. Date: 2000-12-21; WO1999US10291 Applic. Date: 1999-05-11; US19990129099P Applic. Date: 1999-04-13; US19990127626P Applic. Date: 1999-04-01; US19980085053P Applic. Date: 1998-05-11

Inventor: SALITURO FRANCESCO [US]; GALULLO VINCENT [US]; BELLON STEVEN [US]; BEMIS GUY [US]; COCHRAN JOHN [US]


Application No.: US20090076023A1  Published: 19/Mar/2009

Title: Local Anesthetic Methods and Kits

Applicant/Assignee: NOVALAR PHARMACEUTICALS, INC

Application No.: 12/275556   Filing Date: 21/Nov/2008

Abstract:

Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. Also disclosed are kits comprising a local anesthetic, an alpha adrenergic receptor agonist and a low dose of an alpha adrenergic receptor antagonist.

Priority: SE19960002943 Applic. Date: 1996-08-07; US2003-668248 Applic. Date: 2003-09-24; US2002-155171 Applic. Date: 2002-05-28; US2001-852751 Applic. Date: 2001-05-11; US20000203800P Applic. Date: 2000-05-12; US20000235855P Applic. Date: 2000-09-27

Inventor: WEBER ECKARD [US]; KATZ HOWARD I [US]


Application No.: US20090076061A1  Published: 19/Mar/2009

Title: MUSCARINIC ACETYCHOLINE RECEPTOR ANTAGONISTS

Applicant/Assignee:

Application No.: 11/573099   Filing Date: 02/Feb/2007

Abstract:

Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.

Priority: US20040600213P Applic. Date: 2004-08-06; WO2005US27957 Applic. Date: 2005-08-05

Inventor: BUSCH-PETERSEN JAKOB [US]; PALOVICH MICHAEL R [US]; LAINE DRAMANE IBRAHIM [US]


Application No.: US20090076182A1  Published: 19/Mar/2009

Title: One-pack type dental adhesive composition

Applicant/Assignee: KABUSHIKI KAISHA SHOFU

Application No.: 12/230225   Filing Date: 26/Aug/2008

Abstract:

An object of the present invention is to provide a one-pack type dental adhesive composition which can exhibit excellent adhesion to any material, for example, dental ceramics, organic composites containing inorganic compounds, dental noble metals and dental non-noble metals, and also has excellent storage stability. Disclosed is a one-pack type dental adhesive composition comprising a silane coupling agent as a component (a), an acidic group-containing polymerizable monomer as a component (b), a sulfur atom-containing polymerizable monomer as a component (d), and other components.

Priority: JP20070239651 Applic. Date: 2007-09-14

Inventor: TANAKA HISAKI [JP]; FUJII TOSHIHIDE [JP]; YAMAGUCHI YUTAKA [JP]; DEGUCHI MIKITO [JP]


Application No.: US20090076183A1  Published: 19/Mar/2009

Title: Radiation curable methacrylate polyesters

Applicant/Assignee:

Application No.: 11/919743   Filing Date: 28/Apr/2006

Abstract:

A radiation curable composition comprising a (meth)acrylated polyester having unsaturated (meth)acrylic groups on the molecules, responding to formula (I) or formula (II) wherein each D, independently, represents ethylene or propylene, x, y is an integer from (1) to (50), each A, independently, represent hydrogen, alkyl, alkenyl, with the proviso that adjacent A's can be linked together to form a cycle, each B, independently, represents an alkylene or alkenylene chain, optionally comprising one or more ether bridges, each R, independently, represents hydrogen or methyl.

Priority: US20050677346P Applic. Date: 2005-05-04; WO2006EP04012 Applic. Date: 2006-04-28

Inventor: CHIAO JOHN JUN [US]; ARCENEAUX JOANN [US]


Application No.: US20090076189A1  Published: 19/Mar/2009

Title: ONE-PACKAGE DENTAL ADHESIVE COMPOSITION

Applicant/Assignee: TOKUYAMA DENTAL CORPORATION

Application No.: 12/276585   Filing Date: 24/Nov/2008

Abstract:

An adhesive composition comprising (A) a polymerizable monomer component containing not less than 5% by mass of an acidic group-containing polymerizable monomer, (B) a polyvalent metal ion-eluting filler, (C) a volatile organic solvent, and (D) water, wherein the polyvalent metal ion-eluting filler (B) is blended in such an amount that the amount of the polyvalent metal ions eluted out from the filler becomes 1.0 to 7.0 meq per gram of the polymerizable monomer component (A), the volatile organic solvent (C) is blended in an amount in a range of 30 to 150 parts by mass per 100 parts by mass of the polymerizable monomer component (A) and so as to satisfy 20.X parts by mass or more (X is a number representing the amount of elution of the polyvalent metal ions), and the water (D)

is blended in an amount of 3 to 30 parts by mass per 100 parts by mass of the polymerizable monomer component (A). The composition maintains a large strength of adhesion to the teeth, can be preserved in the form of one package, and can be used as a material for pre-treating the teeth and as a dental adhesive.

Priority: JP20060147203 Applic. Date: 2006-05-26; JP20060239951 Applic. Date: 2006-09-05; JP20060284322 Applic. Date: 2006-10-18; WO2007JP61148 Applic. Date: 2007-05-25

Inventor: MATSUSHIGE KOJI [JP]; OGURI MAKOTO [JP]; SHIMIZU SHIZUKA [JP]; SUZUKI TAKESHI [JP]


Application No.: US20090076548A1  Published: 19/Mar/2009

Title: Teething fingers

Applicant/Assignee:

Application No.: 11/901833   Filing Date: 19/Sep/2007

Abstract:

A teething device for use by an infant. The teething device has a base manufactured from a first predetermined material and the base has a first predetermined size and a first predetermined shape. There is at least one projection protruding from a first predetermined side of the base such that the at least one projection will fit in an infant's mouth. The at least one projection is manufactured from a second predetermined material and has a second predetermined size and a second predetermined shape. A handle member manufactured from a third predetermined material and has a third predetermined size and a third predetermined shape and the handle member protrudes from a second predetermined side of the base.

Priority:

Inventor: LETSCHE JANE [US]


Application No.: US20090078214A1  Published: 26/Mar/2009

Title: PET TOY FOR RETAINING REPLACEABLE TREATS, AND METHODS

Applicant/Assignee:

Application No.: 11/858675   Filing Date: 20/Sep/2007

Abstract:

Pet toys configured to accept an edible or chewable treat which can be readily replaced. The pet toys have a first portion and a second portion which releaseably engage to retain the edible treat with the toy until the treat is consumed or otherwise removed from the toy by the pet. When desired, the toy can be disassembled by removing the first portion from the second portion, new treats can be added to the toy, and the two portions reassembled.

Priority:

Inventor: MANN CHARLES DAVID [US]


Application No.: US20090078257A1  Published: 26/Mar/2009

Title: Auto-Titration of Positive Airway Pressure Machine With Feedback From Implantable Sensor

Applicant/Assignee: PAVAD MEDICAL, INC

Application No.: 12/235538   Filing Date: 22/Sep/2008

Abstract:

Systems and methods for detecting and treating an obstructive sleep apnea event are disclosed herein. The systems and methods may use an electrical output generating ionic polymer metal composite sensor attached to a region in an airway passage in an oral cavity. The electrical output may be wirelessly transmitted as a signal for indication of an obstructive sleep apnea event. The signal may be further analyzed by a positive airway pressure system for treatment of the obstructive sleep apnea event.

Priority: US2006-613027 Applic. Date: 2006-12-19; US2004-946435 Applic. Date: 2004-09-21; US2005-233493 Applic. Date: 2005-09-21; US2006-355927 Applic. Date: 2006-02-15; US20080055405P Applic. Date: 2008-05-22

Inventor: BHAT NIKHIL D [US]; HEGDE ANANT V [US]; YUNG CHARISSE M [US]; CHOI GEORGE Y [US]


Application No.: US20090078671A1  Published: 26/Mar/2009

Title: SEALING DISC WITH TAB FOR CLOSING A CONTAINER HAVING A PLUG OR CAP CLOSURE AND FABRICATION METHOD

Applicant/Assignee: MANUFACTURE GENERALE DE JOINTS

Application No.: 12/200364   Filing Date: 28/Aug/2008

Abstract:

Sealing disc (1) for closing a container having a plug or cap closure, comprising a support (2) to be positioned at the bottom of the plug or of the cap, joined by means of a temporary adhesive (7) to a membrane seal (3) to be sealed on the mouth of the container, the membrane seal (3) being provided on all or part of its thickness with a prolongation constituting a pull tab (4), characterized in that the whole surface of the tab is folded back on the face of the membrane seal (3) in contact with the corresponding face of the support (2).

Priority: FR20070057839 Applic. Date: 2007-09-25

Inventor: TRIQUET STEPHANE [FR]; BISCHOFF REMY [FR]


Application No.: US20090079993A1  Published: 26/Mar/2009

Title: Dental Optical Coherence Tomograph

Applicant/Assignee: SHOFU INC

Application No.: 12/085423   Filing Date: 22/Nov/2006

Abstract:

A dental optical coherence tomography apparatus for measuring tissue in a stomatognathic region of a living body or an artificial composition in the stomatognathic region as a measured object includes: a variable wavelength light source (15)

a light splitting portion (19) that splits light-source light emitted from the variable wavelength light source (15) into reference light (29) and measuring light (28)

an interference portion (19) that causes the measuring light (28) and the reference light (29) to interfere with each other, thereby generating interference light

a photodetection portion (41) that measures the interference light

and an arithmetic portion (27b) that generates an image of a measured object (22) by Fourier transforming or inverse Fourier transforming the intensity of the interference light, whose wavelength changes with time, that has been detected by the photodetection portion for each of the wavelengths. Accordingly, an optical coherence tomography apparatus applicable to dental measurement can be provided.

Priority: JP20050337372 Applic. Date: 2005-11-22; WO2006JP323279 Applic. Date: 2006-11-22

Inventor: YATAGAI TOYOHIKO [JP]; YASUNO YOSHIAKI [JP]; TAMURA MASAMI [JP]


Application No.: US20090081134A1  Published: 26/Mar/2009

Title: Oral Care Compositions Comprising Tropolone Compounds and Essential Oils and Methods of Using The Same

Applicant/Assignee:

Application No.: 12/329210   Filing Date: 05/Dec/2008

Abstract:

The present invention relates to oral care compositions suitable for preventing or treating diseases or conditions of the oral cavity in warm-blooded animals including humans, comprising an oral care effective amount of at least one tropolone compound in combination with at least one essential oil, and a pharmaceutically acceptable oral carrier. This invention further relates to a method for preventing or treating diseases or conditions of the oral cavity in warm-blooded animals including humans, by applying an oral care effective amount of the oral care composition to the oral cavity.

Priority: US2004-766366 Applic. Date: 2004-01-28; US2002-207726 Applic. Date: 2002-07-29

Inventor: PAN PAULINE [US]; FINNEGAN MARYBETH [US]; SOSHINSKY ANDRE [US]; ARVANITIS GEORGIA [US]; BERARDINI MICHAEL [US]


Application No.: US20090081135A1  Published: 26/Mar/2009

Title: Iodine-based oral antibacterial treatment methodology

Applicant/Assignee:

Application No.: 11/903583   Filing Date: 24/Sep/2007

Abstract:

An iodine-based oral antibacterial treatment methodology involves applying an effective amount of an iodine-based oral antibacterial treatment to the inside of a human or animal mouth in the gum area between the gum and a tooth wall. The delivered treatment includes available iodine, including molecular iodine, and an iodine free radical initiator selected from the group consisting of chloride ions, bromide ions and mixtures thereof. Animals include pets, such as dogs and cats, as well as farm animals having teeth, e.g., horses, cows, goats and the like, and zoo animals having teeth, such as chimps, baboons, tigers and the like.

Priority:

Inventor: GLEN JEFFREY D [US]


Application No.: US20090081235A1  Published: 26/Mar/2009

Title: PSEUDOMONAS EXOTOXIN A-LIKE CHIMERIC IMMUNOGENS FOR ELICITING A SECRETORY IGA-MEDIATED IMMUNE RESPONSE

Applicant/Assignee: OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES GENENTECH, INC

Application No.: 12/169438   Filing Date: 08/Jul/2008

Abstract:

This invention provides methods of eliciting a secretory IgA-mediated immune response in a subject by administering a Pseudomonas exotoxin A-like chimeric immunogens that include a non-native epitope in the Ib domain of Pseudomonas exotoxin. Compositions comprising secretory IgA antibodies that specifically recognize an epitope of HIV-1 also are provided.

Priority: US2003-659036 Applic. Date: 2003-09-09; US2000-462713 Applic. Date: 2000-05-12; WO1998US14336 Applic. Date: 1998-07-10; US19970056924P Applic. Date: 1997-07-11

Inventor: FITZGERALD DAVID J [US]; MRSNY RANDALL J [US]


Application No.: US20090081294A1  Published: 26/Mar/2009

Title: Sustained release dosage form for lubricating an oral cavity

Applicant/Assignee:

Application No.: 11/904333   Filing Date: 26/Sep/2007

Abstract:

Aspects of the invention include a sustained release dosage form that can be administered to an oral cavity, e.g., the mouth. In certain embodiments, the sustained release dosage form is formulated as a lozenge or gum that may be administered to an oral cavity for the purpose of providing lubrication therein. In certain embodiments, the sustained release dosage form not only provides lubrication to a mucosal surface of an oral cavity, but also provides for the sustained release of a flavoring and/or beneficial agent. Accordingly, in certain embodiments, the sustained release dosage form includes a water-insoluble polymer, e.g., ethylcellulose, an essential oil component, and an effective amount of a film forming binder, e.g., xanthan gum. In certain embodiments, the effective amount of the film forming binder and the type of film forming binder are selected so as to provide the sustained release dosage with the capability of lubricating one or more mucosal surfaces within an oral cavity when the dosage form is positioned therein. In certain embodiments, the sustained release dosage form is formulated in a manner sufficient to form a matrix that includes the various components of the sustained release dosage form, such that when positioned in an oral cavity the matrix slowly dissolves and thereby lubricates the oral cavity and/or delivers a flavoring and/or beneficial agent thereto. Methods of formulating such dosage forms and administering them to an oral cavity for the treatment of an adverse condition are also provided.

Priority:

Inventor: GIN JERRY B [US]; ROSS BENJAMIN F [US]


Application No.: US20090081607A1  Published: 26/Mar/2009

Title: DENTAL RINSING UNIT

Applicant/Assignee:

Application No.: 12/280437   Filing Date: 21/Feb/2007

Abstract:

The invention relates to a cleaning container (12) comprising an inlet (120) which is connected to the water container (11), and an outlet for connecting a suction tube (43), the outlet (122) being embodied as a hydrant (124) for a suction handpiece (42) applied to the suction tube (43). The cleaning container (12) can be filled with the water from the water container (11) especially by means of a negative pressure applied to the outlet when the suction tube (43) is connected.

Priority: DE200610008944 Applic. Date: 2006-02-23; WO2007EP51635 Applic. Date: 2007-02-21

Inventor: FREY HANS-PETER [DE]


Application No.: US20090081611A1  Published: 26/Mar/2009

Title: METHODS, DEVICES, SYSTEMS, ASSEMBLIES, AND KITS FOR TISSUE RETRACTION IN AN ORAL CAVITY

Applicant/Assignee: INDENTIV, LLC

Application No.: 12/239477   Filing Date: 26/Sep/2008

Abstract:

Provided herein is a retraction device for retracting soft tissue from the dental surfaces in the oral cavity of a patient. The retraction device is comprised of a topology conformable structure, where the topology conformable structure is adaptable to be delivered to the oral cavity in a constrained shape. The device can then undergo a conformation change in the oral cavity, where the device transforms into its unconstrained shape. The unconstrained shape of the device creates a useable working field in the oral cavity. The useable working field can provide increased accessibility to and/or visibility within the oral cavity. Also provided herein are methods for using the device and kits.

Priority: US20070975387P Applic. Date: 2007-09-26; US20080026989P Applic. Date: 2008-02-07; US20080081908P Applic. Date: 2008-07-18

Inventor: HINES CRAIG [US]; PONTYNEN CURTIS [US]


Application No.: US20090082287A1  Published: 26/Mar/2009

Title: METHODS OF ENHANCING MUCOSAL HYDRATION AND MUCOSAL CLEARANCE BY TREATMENT WITH SODIUM CHANNEL BLOCKERS AND OSMOLYTES

Applicant/Assignee: PARION SCIENCES, INC

Application No.: 11/852003   Filing Date: 07/Sep/2007

Abstract:

The present invention relates to methods and compositions for treating diseases ameliorated by increased mucociliary clearance and mucosal hydration by administering an effective amount of a sodium channel blocker as defined herein and an osmolyte to a subject to a subject in need of increased mucociliary clearance and mucosal hydration.

Priority: US20060842963P Applic. Date: 2006-09-08; US20060842669P Applic. Date: 2006-09-07

Inventor: JOHNSON MICHAEL ROSS [US]; BOUCHER RICHARD C [US]; HIRSH ANDREW J [US]


Application No.: US20090082342A1  Published: 26/Mar/2009

Title: N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS

Applicant/Assignee: ACADIA PHARMACEUTICALS, INC

Application No.: 12/234582   Filing Date: 19/Sep/2008

Abstract:

Disclosed herein are isolated forms of the compounds of Formula (I), (II), (III), (IV) and (V), or a pharmaceutically acceptable salt, prodrug, hydrate, solvate, polymorph, or ester thereof. Also disclosed are methods of inhibiting an activity of a serotonin receptor, methods inhibiting an activation of a serotonin receptor, and methods of alleviating or treating various disease conditions and side effects.

Priority: US20070974426P Applic. Date: 2007-09-21; US20080050976P Applic. Date: 2008-05-06

Inventor: ULDAM HENRIETTE KOLD [DK]; THYGESEN MIKKEL BOAS [DK]


Application No.: US20090082354A1  Published: 26/Mar/2009

Title: PYRAZOLO[5, 1-C] [1,2,4] TRIAZINES, METHODS FOR PREPARATION AND USE THEREOF

Applicant/Assignee: WYETH

Application No.: 12/233877   Filing Date: 19/Sep/2008

Abstract:

A pyrazolo[5,1-c][1,2,4]triazine compound of formula A: and pharmaceutically acceptable sats thereof. The multiply-substituted pyrazolo[5,1-c][1,2,4]triazine compounds of the invention selectively inhibit B-Raf kinase activity and are useful for treating disorders mediated by B-Raf kinase.

Priority: US20070994589P Applic. Date: 2007-09-20

Inventor: BERGER DAN MAARTEN [US]; DUTIA MINU DHANJISHA [US]; HOPPER DARRIN WILLIAM [US]; TORRES NANCY [US]


Application No.: US20090082358A1  Published: 26/Mar/2009

Title: Vanilloid receptor ligands and their use in treatments

Applicant/Assignee:

Application No.: 12/284586   Filing Date: 22/Sep/2008

Abstract:

Bicyclic 3,4-fused piperidine compounds, and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotizing agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

Priority: US20070994759P Applic. Date: 2007-09-20

Inventor: NISHIMURA NOBUKO [US]; NORMAN MARK H [US]; TAMAYO NURIA [US]; TANG PHI [US]; BO YUNXIN Y [US]


Application No.: US20090082706A1  Published: 26/Mar/2009

Title: Shower head attachment with a pulsator used to clean teeth

Applicant/Assignee: HEALTH AND HYGIENE INC

Application No.: 11/900764   Filing Date: 13/Sep/2007

Abstract:

A valve for adjusting the flow of water through an oral irrigation device is connected to a shower head by a flexible conduit. The valve is located on a handle connected to a water-dispensing pick for cleaning teeth and gums. An impeller-type pump is provided in the flexible conduit to pulsate the water.

Priority:

Inventor: SHAW DANIEL A [US]


Application No.: US20090084398A1  Published: 02/Apr/2009

Title: ORAL HYGIENE SYSTEM

Applicant/Assignee: JEAN FINOLE, LLC

Application No.: 12/238512   Filing Date: 26/Sep/2008

Abstract:

An integrated oral health hygiene system including at least one oral health care product such as a tooth brush, dental floss and dental rinse/wash. In addition, the system includes instructions for using the oral health care product(s) and a coupon for providing a user access to at least one of discounted and complimentary medical professional services relating to oral health care.

Priority: US20070975656P Applic. Date: 2007-09-27

Inventor: LETANG RANDY D [US]; IRBY DALE [US]


Application No.: US20090084753A1  Published: 02/Apr/2009

Title: Process For Tooling For Manufacture Of A Composite Part Composite Stopper Obtained By Such A Process Or Such Tooling

Applicant/Assignee:

Application No.: 12/207805   Filing Date: 10/Sep/2008

Abstract:

This manufacturing process of a composite part (B), including a stamped body (11, 12) and an injected polymer material part (14), includes steps consisting of: a) placing a blank (1) of a body (11, 12) between a support (456) and a mold (31, 32), such that the said hollow part forms a pattern cavity (33) communicating with an opening (13) going through the blank (1)

b) stamping the blank (1) using a punch (8)

c) placing the holder (456) in a position in which it defines with the blank (1) at least one cavity (400) and in which there is at least one injection runner (50-60) leading to the said cavity (400). d) injecting the polymer material through the injection runner (50-60), said cavity (400) and said opening (13), so as to fill the said pattern cavity (33)

and e) removing the composite part (B) from the mold.

Priority: FR20070006819 Applic. Date: 2007-09-28

Inventor: RAMOS VICTOR [FR]


Application No.: US20090087391A1  Published: 02/Apr/2009

Title: FOAMABLE FLUORIDE ORAL CARE COMPOSITION

Applicant/Assignee:

Application No.: 11/865457   Filing Date: 01/Oct/2007

Abstract:

A dental fluoride foam composition comprising an aqueous solution of a water soluble fluoride ion releasable salt, a surfactant selected from the group consisting of nonionic surfactants, zwitterionic surfactants, betaine surfactants and mixtures thereof

and an orally compatible acidifying agent in an amount sufficient to adjust the pH of the composition to about 3 to about 5. The composition is stable at low temperatures and is a clear solution substantially free of precipitates when held at 4.4 DEG C. for 12 hours. When dispensed from a container into the trough of a dental tray, the composition forms a low density, rapidly collapsible foam which substantially liquefies in about 1 minute after being dispensed from the foam generating container and placed in contact with a patient's teeth.

Priority:

Inventor: JOZIAK MARILOU THERESA [US]; FISHER STEVEN WADE [US]


Application No.: US20090087393A1  Published: 02/Apr/2009

Title: Dental Treatment Compositions and Conformable Dental Treatment Trays Using the Same

Applicant/Assignee: CAO GROUP, INC

Application No.: 12/329583   Filing Date: 06/Dec/2008

Abstract:

The present invention is a formable dental treatment tray utilizing poly(2-ethyl-2-oxazoline) and a gelatinous active. Blending of the active is accomplished by mixing the Poly(2-ethyl-2-oxazoline) with an active ingredient, such as a peroxide like hydrogen peroxide, carbamide peroxide, sodium perborate, or sodium percarbonate, usually also with water or an appropriate organic solvent. Peroxide concentrations in these new gels can reach a 30% concentration of hydrogen peroxide while maintaining a shelf life of six months at room temperature without developing peroxide decomposition. The gels are applied to an appropriate backing and dried to a gelatinous state. In use, the active is hydrated and regains adhesiveness. Then the tray is pressed and formed around a user's dental arch to form the customizable tray. Multiple active ingredients may be used, with or without peroxide, for accomplishing desired treatment regimens.

Priority: US2008-329582 Applic. Date: 2008-12-06; US2006-307463 Applic. Date: 2006-02-08

Inventor: JENSEN STEVEN D [US]; CAO DENSEN [US]


Application No.: US20090087501A1  Published: 02/Apr/2009

Title: Oral Compositions Containing Botanical Extracts

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/243669   Filing Date: 01/Oct/2008

Abstract:

The disclosure provides oral compositions having at least two botanical active ingredients derived from plants. The oral composition also includes an orally acceptable vehicle to deliver an effective amount of the at least two active ingredients in vivo. The botanical active ingredients provide particularly efficacious antimicrobial (antibacterial, antiviral, and/or antifungal), antioxidant, anti-inflammatory, anti-ageing, and or healing properties to the oral compositions.

Priority: US20070976508P Applic. Date: 2007-10-01

Inventor: CUMMINS DIANE [US]


Application No.: US20090087759A1  Published: 02/Apr/2009

Title: Oxime Ester Photoinitiators

Applicant/Assignee:

Application No.: 12/085383   Filing Date: 08/Nov/2006

Abstract:

Compounds of the formula (I), (II), and wherein R1, R2, R'2 and R'''2 for example are C1-C20alkyl

R3, R4, and R5 for example independently of one another are hydrogen or a defined substituent provided that at least one of R3, R4 or R5 is other than hydrogen or C1-C20alkyl

R6, R7, R8, R'6, R'7, R'8, R''6, R''7, R'''6 and R'''7 for example independently of one another have one of the meanings as given for R3, R4, and R5

and R9 for example is C1-C20alkyl

exhibit an unexpectedly good performance in photopolymerization reactions.

Priority: EP20050111539 Applic. Date: 2005-12-01; WO2006EP68202 Applic. Date: 2006-11-08

Inventor: MATSUMOTO AKIRA [JP]; TANABE JUNICHI [JP]; KURA HISATOSHI [JP]; OHWA MASAKI [JP]


Application No.: US20090087812A1  Published: 02/Apr/2009

Title: SELF-CUSTOMIZABLE DENTAL TREATMENT TRAYS

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/865867   Filing Date: 02/Oct/2007

Abstract:

A self-customizable dental tray usable in a dental application is prepared as follows: providing a barrier layer in the shape of a dental treatment tray having a wall thickness of less than or about 1 mm

introducing a curable elastomeric material onto an impression-receiving surface of the barrier layer

placing the barrier layer having the curable elastomeric material onto the teeth so that the curable elastomeric material forms an impression layer

and allowing the curable elastomeric material to cure so as to form an impression layer having a teeth-receiving surface with contours adapted to conform with the teeth, said impression layer having a wall thickness of less than or about 1 mm. Optionally, the barrier layer is a liner that can be separated from a support tray that provides a tray shape to the liner.

Priority:

Inventor: ANDERSEN SCOT N [US]


Application No.: US20090090359A1  Published: 09/Apr/2009

Title: Respiratory Anaesthesia Apparatus with Device for Measuring the Xenon Concentration

Applicant/Assignee: L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE

Application No.: 12/097216   Filing Date: 11/Dec/2006

Abstract:

Apparatus for respiratory anaesthesia of a patient by administration of a gas containing gaseous xenon, with a main gas circuit which is open or closed and has an inhalation branch and an exhalation branch, means for supply of gaseous xenon to the inhalation branch of the main circuit, and means for determining the xenon concentration. The means for determining the xenon concentration comprise at least one hot-wire sensor having at least one electrically conducting wire in direct contact with the gaseous flow containing the xenon, calculating means that cooperate with the hot-wire sensor(s) in order to determine the xenon concentration (Xe %) in the flow, means for generating an electrical current in order to generate a current in at least one hot wire, and means for voltage measurement that can measure at least one voltage value at the terminal of at least one hot wire or at least one resistance arranged in series with at least one hot wire. The calculating means cooperate with the voltage measurement means in such a way as to determine the xenon concentration (Xe %).

Priority: FR20050053862 Applic. Date: 2005-12-14; WO2006FR51326 Applic. Date: 2006-12-11

Inventor: DAVIET CHRISTIAN [FR]; BLANDIN RICHARD [FR]; KISSI NOUREDDINE [FR]


Application No.: US20090090371A1  Published: 09/Apr/2009

Title: CONTINOUSLY ADJUSTABLE MANDIBULAR PROTRUSION SPLINT FOR TREATING SNORING AND OBSTRUCTIVE SLEEP APNOEA

Applicant/Assignee:

Application No.: 11/719680   Filing Date: 23/Nov/2005

Abstract:

The invention relates to a two-part mandibular protrusion splint (1) for preventing snoring and/or obstructive sleep apnoea, comprising a lower part (2) and an upper part (3), comprising shaping and flexurally rigid trays (2a, 3a) which are open towards the mandibula and maxilla respectively, where the bottom surfaces of the outsides of the two trays (2a, 3a) are connected to one another in such a way that they are continuously adjustable relative to one another in the longitudinal direction, and a corresponding ready-to-use set for the production or restoration of mandibular protrusion splints consisting of (i) shaping and flexurally rigid trays (2a, 3a) with preformed attachment elements on the outsides of each of the bottom surfaces

(ii) one or more adjustment screws (10) for connecting the attachment elements

and (iii) optionally use instructions.

Priority: DE200410058081 Applic. Date: 2004-12-01; DE200520015106U Applic. Date: 2005-09-24; WO2005DE02095 Applic. Date: 2005-11-23

Inventor: TOUSSAINT WINFRIED [DE]


Application No.: US20090090373A1  Published: 09/Apr/2009

Title: Cigarette Having Configured Lighting End

Applicant/Assignee: R.J. REYNOLDS TOBACCO COMPANY

Application No.: 11/868264   Filing Date: 05/Oct/2007

Abstract:

The lighting end or tip of the smoking article is configured in such a manner that the entire front or upstream face thereof does not lie in a plane that is generally perpendicular to the longitudinal axis of the smoking article. For example, at least a portion of the front face of the smoking article lies in a plane (e.g., a generally flat plane) that is positioned about 40 DEG to about 50 DEG relative to the longitudinal axis of that smoking article. As such, the overall nature or character of the mainstream aerosol generated by a smoking article can be altered. This shape may include an ellipse, or may include a first section in a plane not perpendicular to the longitudinal axis and a second section in a plane perpendicular to the longitudinal axis.

Alternatively, the face of the lighting end may have a shape such that its surface area is greater than the cross-sectional area of the smoking article.

Priority:

Inventor: BORSCHKE AUGUST JOSEPH [US]; BROWN BUDDY GENE [US]


Application No.: US20090090380A1  Published: 09/Apr/2009

Title: Flossing and Oral Hygiene Tool

Applicant/Assignee:

Application No.: 12/239984   Filing Date: 29/Sep/2008

Abstract:

A detachable device for improved dental hygiene supports and tensions dental floss above and beyond the bristles of the tooth brush so that flossing can occur using the bristle end of the tooth brush and avoid having the bristles interfere with the flossing process. In preferred embodiments the device is mechanically coupled to a sonic toothbrush to transmit sonic energy to the floss for improved cleaning. In other embodiments the device includes a tongue cleaning implement.

Priority: US20070978036P Applic. Date: 2007-10-05

Inventor: CULVER KAREN [US]


Application No.: US20090092562A1  Published: 09/Apr/2009

Title: Oral Care Composition To Reduce Or Eliminate Dental Sensitivity

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/275361   Filing Date: 21/Nov/2008

Abstract:

The invention includes an oral care composition that reduces and/or eliminates the perception of tooth sensitivity. The composition includes an adherent material and particles having an average particle size of about 8 microns or less. The particles are present in the composition in an amount of about 5% by weight. Also included within the scope of the invention are related methods, such as methods of occluding a dentin tubule.

Priority: US2008-103919 Applic. Date: 2008-04-16; US2007-742039 Applic. Date: 2007-04-30

Inventor: ZAIDEL LYNETTE [US]; CHOPRA SUMAN K [US]; PRENCIPE MICHAEL [US]; WANG QIN [US]; CHRISTOPOULOU CONSTANTINA [US]


Application No.: US20090092563A1  Published: 09/Apr/2009

Title: ACTIVATING BRUSH TIP APPLICATORS FOR DENTAL BLEACHING COMPOSITIONS

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/866532   Filing Date: 03/Oct/2007

Abstract:

A brush tipped applicator includes an applicator tip having a body defining an external surface and an internal conduit. The applicator tip body can have a proximal end defining a proximal opening of the internal conduit and a distal end. The proximal end of the applicator tip body can have a first fastener that is configured for being coupled to a fastener (i.e., second fastener) of a member containing the dental bleaching composition such that the internal conduit of the applicator tip body is capable of being fluidly coupled with the dental bleaching composition. Additionally, the brush tip includes at least one filament disposed on the external surface of the applicator tip body. A dental bleach activator disposed within the filament in an amount sufficient for activating the dental bleaching composition for whitening the teeth.

Priority:

Inventor: ALLRED PETER M [US]; VU DAVID Q [US]


Application No.: US20090092565A1  Published: 09/Apr/2009

Title: DENTAL ENAMEL RECALCIFICATION ACCELERATOR AND CONTAINING THE SAME, ORAL COMPOSITION AND FOOD OR BEVERAGE

Applicant/Assignee: LOTTE CO., LTD

Application No.: 11/914877   Filing Date: 24/May/2005

Abstract:

A dental enamel recalcification accelerator that even when used in oral compositions and food or beverage, poses no safety problem, and that is capable of effectively promoting the recalcification of decalcified dental enamel to thereby positively suppress any dental caries

and containing the same, an oral composition and food or beverage. There is provided a dental enamel recalcification accelerator comprising anhydrogalactose-containing red algae and/or an extract thereof as an active ingredient. Further, there are provided an oral composition and food or beverage comprising the dental enamel recalcification accelerator.

Priority: JP20050147109 Applic. Date: 2005-05-19; WO2005JP09466 Applic. Date: 2005-05-24

Inventor: KOYAMA TAKAAKI [JP]; SUGITA DAIGO [JP]; ASADA SHINYA [JP]; SHIMURA SUSUMU [JP]


Application No.: US20090092643A1  Published: 09/Apr/2009

Title: Foam Strip for the Delivery of Oral Care Compositions

Applicant/Assignee:

Application No.: 11/918168   Filing Date: 11/Apr/2005

Abstract:

The present invention relates to a polyurethane foam strip (1), shaped for the application to the labile surface of the front teeth and/or gums of a subject, which strip is provided with one or more oral care compositions for delivery to the teeth and/or gums of the subject. It further relates to its use for delivery of compositions, specifically for whitening teeth. It further relates to use of the strip in combination with a dental device.

Priority: WO2005EP03779 Applic. Date: 2005-04-11

Inventor: DE VREESE GUY [BE]; LOMBAERT POL [BE]


Application No.: US20090092664A1  Published: 09/Apr/2009

Title: POLYMER-METAL CHELATOR CONJUGATES AND USES THEREOF

Applicant/Assignee: UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION

Application No.: 12/243671   Filing Date: 01/Oct/2008

Abstract:

The present invention provides prodrugs comprising a polymer conjugated to a metal chelator via a disulfide bond. For example, D-penicillamine may be conjugated to a polymer (e.g., gelatin, chitosan, polyglutamic acid) via a linker, such as SPDP. Thus, the cellular delivery and pharmacokinetics of D-penicillamine can be substantially improved. Methods for the treatment of cancer using compositions of the present invention are also disclosed.

Priority: US20070978356P Applic. Date: 2007-10-08

Inventor: MUMPER RUSSELL J [US]; GUPTE ANSHUL [US]; WADHWA SAURABH [US]


Application No.: US20090093389A1  Published: 09/Apr/2009

Title: Anti-corrosion detergent compositions and use of same in cleaning dental and medical instruments

Applicant/Assignee: SCICAN

Application No.: 12/314282   Filing Date: 08/Dec/2008

Abstract:

A novel method for cleaning dental and medical instruments is disclosed, in which a cleaning solution including a low-residue corrosion inhibitor is used not only in a wash stage of the cleaning cycle, but also in at least one subsequent rinse cycle, to optimize both cleaning and rust prevention. A novel cleaning solution particularly suited to this method has a neutral to alkaline pH and comprises in aqueous solution a low-foaming surfactant and a corrosion inhibitor selected from the group of C4-C16 alkyl pyrrolidones and C1-C18 alkylamines.

Priority: US2006-353049 Applic. Date: 2006-02-14; US20050652701P Applic. Date: 2005-02-15

Inventor: TIJANIC VESO [CA]; BHARAJ BHUPINDER [CA]; ACOSTA ZARA EDGAR JOEL [CA]; OMIDBAKHSH NAVID [CA]


Application No.: US20090093563A1  Published: 09/Apr/2009

Title: DENTAL ADHESIVE AND METHOD OF USE

Applicant/Assignee: KERR CORPORATION

Application No.: 11/868748   Filing Date: 08/Oct/2007

Abstract:

A dental adhesive composition comprising (i) at least one non-acidic polymerizable monomer having at least one ethylenically unsaturated group, (ii) optionally one or more acidic compounds, (iii) at least one photoinitiator, (iv) at least one solvent, and (v) about 0-40% by weight of one or more fillers

wherein the weight ratio of non-acidic polymerizable monomers/acidic compounds in the adhesive composition is more than about 4.5

the viscosity of the adhesive composition is less than about 350 centipoise (cP) at 25 DEG C.

and the adhesive composition excluding solvent and filler has an acid number of less than about 0.75 mmol NaOH/g. The dental adhesive composition is used with a dental primer composition, which may be provided together in a kit.

Priority:

Inventor: QIAN XUEJUN [US]


Application No.: US20090095164A1  Published: 16/Apr/2009

Title: METHOD OF ENHANCING BEVERAGES BY MEANS OF A UNIQUE MICROENCAPSULATED DELIVERY SYSTEM

Applicant/Assignee:

Application No.: 12/121809   Filing Date: 16/May/2008

Abstract:

The present invention provides a method of imparting flavor enhancers, (flavorings) flavor or aroma masking agents, medicinal additives, fragrances, vitamins, colorants, homeopathic and herbal remedies, appearance and characteristic modifiers and other ingredients to a brewed or steeped beverage such as coffee or tea by means of a microencapsulated delivery system incorporated onto a substrate or filter material such as those used in drip coffee makers or tea bags. The microcapsules are "printed" or laminated to the substrate filter paper in a pattern that allows water to pass through while the microcapsules filled with a flavoring liquid or solid is dissolved thus releasing the contents into the water stream resulting in a flavor-enhanced beverage. Alternative delivery may also be achieved by means of: a) A microcapsule coated paper disc that may simply be immersed in the hot beverage or

b) A microcapsule coated interior wall of a disposable container or cup (A paper coffee cup for example) until such time the hot fluid within the container dissolves the microcapsules thus releasing the latent additive ingredient or a primary formulation of ingredients constituting the entire beverage solution or mixture. Several variations of this technology may be adapted for use with hot, cold or ambient temperature beverage preparation methods. Further aspects of the invention will become apparent from consideration of the drawings and the ensuing description of preferred embodiments of the invention. A person skilled in the art will realize that other embodiments of the invention are possible and that the details of the invention can be modified in a number of respects, all without departing from the inventive concept. Thus, the following drawings, photos and description are to be regarded as illustrative in nature and not restrictive.

Priority: US20070930586P Applic. Date: 2007-05-17

Inventor: CELESTE SALVATORE ALBERT [US]


Application No.: US20090095313A1  Published: 16/Apr/2009

Title: Smokeless Tobacco Product, Smokeless Tobacco Product in the Form of a Sheet, Extrudable Tobacco Composition, Method for Manufacturing a Smokeless Tobacco Product, Method for Delivering Super Bioavailable Nicotine Contained in Tobacco to a User, and Packaged Smokeless Tobacco Product Sheet

Applicant/Assignee:

Application No.: 12/122201   Filing Date: 16/May/2008

Abstract:

A nonaqueous, extrudable composition includes at least one thermoplastic polymer in an amount of more than 20 wt % of the whole composition and tobacco. A smokeless tobacco product in the form of a sheet can be made by extruding or hot melt shaping a nonaqueous composition comprising at least one thermoplastic polymer and tobacco, the sheet being soluble in a user's mouth and resulting in sustained release of nicotine to the user. The sheet can be in a form that may be placed in the buccal cavity of, on the palate of or sublingually in the user, and have an average dissolution time of 5 to 50 minutes for delivering super bioavailable nicotine to the user.

Priority: US20070979169P Applic. Date: 2007-10-11; US20070990381P Applic. Date: 2007-11-27

Inventor: FUISZ RICHARD C [US]


Application No.: US20090095322A1  Published: 16/Apr/2009

Title: Container cleaning device, container cleaning method, and tank

Applicant/Assignee:

Application No.: 11/919905   Filing Date: 18/Apr/2006

Abstract:

A cleaning device and a cleaning method for a container capable of continuously performing a cleaning treatment, and a tank. The cleaning device includes a jetting member which jets a fluid in the container

a movement unit which relatively moves the jetting member along an axial direction of the container with respect to the container so that the jetting member is inserted into the container from a mouth part of the container

and a switching unit which switches the jetting member from one function to another function. The switching unit switches a nozzle for a cleaning liquid, a nozzle for blowing and a nozzle for drying in order.

Priority: JP20050140874 Applic. Date: 2005-05-13; JP20050141261 Applic. Date: 2005-05-13; JP20050149777 Applic. Date: 2005-05-23; WO2006JP308491 Applic. Date: 2006-04-18

Inventor: WAKAO YOSHITAKA [JP]; MURATE MASASHI [JP]


Application No.: US20090095662A1  Published: 16/Apr/2009

Title: HARVESTING CORN COBS

Applicant/Assignee:

Application No.: 12/252104   Filing Date: 15/Oct/2008

Abstract:

A cart is towed behind a combine harvester for collecting corn cobs and includes a conveyer belt feeding into a system for separating cobs from residue to be discharged and a tank for receiving and transporting the cobs. An unload auger is provided from the tank to one side of the cart while the cart moves forward. Power for driving the cart is obtained from a chopper drive of the combine harvester. The separating arrangement includes a series of sequential blower fans for blowing air through the discharged material as it is discharged from a conveyor and into a spreading guide disperses the residue. The cobs are conveyed using a series of augers where the auger to flight distance is at least 2 inches and particularly a pair of augers feed the cobs through a front wall of the tank so as to push cobs upwardly into the tank.

Priority: US20080087409P Applic. Date: 2008-08-08; US20070986438P Applic. Date: 2007-11-08; US20070979988P Applic. Date: 2007-10-15; US20070981134P Applic. Date: 2007-10-19

Inventor: REDEKOP LEO [CA]; MAYERLE DEAN [CA]; WILLEMS SALTON [CA]


Application No.: US20090095774A1  Published: 16/Apr/2009

Title: APPLIANCE FOR DISPENSING HEATED COSMETIC FLUIDS

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER

Application No.: 11/870432   Filing Date: 11/Oct/2007

Abstract:

A device is provided for delivering a heated cosmetic flowable product. The device includes a base with a cavity housing a tube for receiving the flowable product, a heating system heatingly contacting the tube, and an outlet at a downstream end of the tube. A plastic bottle filled with the product is releasably mounted on the base. A fitment is arranged over an open end of the bottle and includes a slitted membrane. An upstream end of the tube penetrates the membrane to establish flowable communication and a sealing relationship. Product is dispensed from the outlet by applying an external squeeze pressure against a wall of the bottle. No mechanical assist is necessary such as a pump or gearing for transporting fluid product.

Priority:

Inventor: DOMOY BRETT CHRISTOPHER [US]


Application No.: US20090097191A1  Published: 16/Apr/2009

Title: PROTECTIVE ENCLOSURE FOR MODEL VEHICLE

Applicant/Assignee:

Application No.: 11/872872   Filing Date: 16/Oct/2007

Abstract:

The present invention provides for a protective enclosure comprising a base comprising a first continuous mating surface and at least one conveyance aperture, a cover comprising a second continuous mating surface, wherein the second continuous mating surface is configured to form a seal with the first continuous mating surface, and a clamp, wherein at least a portion of the clamp is coupleable to the base, wherein a mouth of the clamp is configured to be offset from the aperture when the clamp is coupled to the base, wherein the clamp comprises a first sealing layer, and wherein the clamp is configured to seal the aperture against contaminants. The protective enclosure may be configured for use in a remotely controllable model vehicle to protect a control module.

Priority:

Inventor: ROBERTS TIMOTHY E [US]; LAMPERT JON KENNETH [US]; ALLMENDINGER OTTO KARL [US]


Application No.: US20090097781A1  Published: 16/Apr/2009

Title: AIRTIGHT STORAGE BAG

Applicant/Assignee:

Application No.: 11/871563   Filing Date: 12/Oct/2007

Abstract:

An airtight storage bag is defined by at least one plastic film formed into a pouch. The pouch has a containment region with an openable mouth. There are a first resealable zone extending across the openable mouth to allow closure of the month, and a second resealable zone also extending across the mouth and located on the containment region side of the first resealable zone to allow airtight closure of the containment region. A vent is located between the first and second resealable zones to allow displacement of fluid from the containment region via the vent. The second resealable zone when sealed seals the containment region from the exterior of the bag.

Priority:

Inventor: TANG LUEN-SING [HK]


Application No.: US20090098178A1  Published: 16/Apr/2009

Title: Porous Coating Loaded with a Liquid or a Solid Substance

Applicant/Assignee:

Application No.: 11/991751   Filing Date: 15/Sep/2006

Abstract:

The present invention relates to a process for manufacturing a porous coating with structures in the micro or nano-size domain characterized by the following steps: -providing a support having a surface, -depositing on said surface one mono-layer of temporary particles, -depositing a coating on said temporary particles in such a way that the thickness of said coating is less than the particle diameter, -eliminating said temporary particles and thereby obtaining a porous coating, the pores of said coating corresponding to the spaces previously occupied by the temporary particles and at least a pail of the pores communicating with the external environment, -applying a coating fixation step, characterized by the fact that it furthermore comprise a filling step where said pores are at least partially filled with a liquid or solid substance. The invention also concerns a coating and an object which can be obtained with this process.

Priority: EP20050108573 Applic. Date: 2005-09-16; WO2006IB53323 Applic. Date: 2006-09-15

Inventor: HOFMANN HEINRICH [CH]; NEFTEL FREDERIC [CH]; PIVETEAU LAURENT-DOMINIQUE [CH]


Application No.: US20090098192A1  Published: 16/Apr/2009

Title: Extrudable and Extruded Compositions for Delivery of Bioactive Agents, Method of Making Same and Method of Using Same

Applicant/Assignee:

Application No.: 12/249456   Filing Date: 10/Oct/2008

Abstract:

A nonaqueous, extrudable composition includes at least one thermoplastic polymer in an amount of more than 20 wt % of the whole composition and tobacco. An extruded bioactive product in the form of a sheet can be made by extruding or hot melt shaping a nonaqueous composition comprising at least one thermoplastic polymer and a bioactive agent, the sheet being soluble in a user's mouth and resulting in sustained release of bioactive to the user. The sheet can be in a form that may be placed in contact with the mucosa of the user, and have an average dissolution time of 5 to 50 minutes for delivering the bioactive to the user.

Priority: US2008-122201 Applic. Date: 2008-05-16; US20070979169P Applic. Date: 2007-10-11; US20070990381P Applic. Date: 2007-11-27; US20080054195P Applic. Date: 2008-05-19

Inventor: FUISZ RICHARD C [US]


Application No.: US20090098503A1  Published: 16/Apr/2009

Title: Foam-generating, hardening compositions for forming impressions of surfaces and impression trays for use therewith

Applicant/Assignee: HERAEUS KULZER GMBH

Application No.: 12/062065   Filing Date: 03/Apr/2008

Abstract:

Foam-generating, hardening composition for making impressions of biological surfaces include A at least one impression material based on i isocyanates, which react with mono- and multi-functional amines and/or compounds having hydroxyl groups, to form urethane or urea, or ii A-silicones, or iii C-silicones, or iv Polyethers, or v alpha-silanes, or vi mixtures of two or more materials i to v, and optionally B at least one foaming agent. Impressions of biological surfaces made from this compound have a foam with closed pores.

Priority: DE200710016791 Applic. Date: 2007-04-05

Inventor: KNISPEL GOTTFRIED [DE]; GRUNWALD MARTIN [DE]; GRUNDLER ANDREAS [DE]


Application No.: US20090098506A1  Published: 16/Apr/2009

Title: Shower head attachment for mixing liquids use to clean teeth

Applicant/Assignee: HEALTH AND HYGIENE INC

Application No.: 11/900763   Filing Date: 15/Oct/2007

Abstract:

A valve for adjusting the flow of water through an oral irrigation device is connected to a shower head by a flexible conduit. The valve is located on a handle connected to a water-dispensing pick for cleaning teeth and gums. Mixing apparatus is provided for injecting a secondary fluid, such as a mouthwash, into the flexible conduit upstream from the pick in a direct stream from the shower head.

Priority:

Inventor: SHAW DANIEL A [US]


Application No.: US20090098509A1  Published: 16/Apr/2009

Title: Dental tooth extraction implement and method thereof

Applicant/Assignee:

Application No.: 11/974486   Filing Date: 15/Oct/2007

Abstract:

This application relates to the field of Dentistry, and in more particular to the atraumatic extraction of teeth. The instant invention is a wedge-shaped extraction rod to be inserted into a pre-drilled root. With a wider than thick configuration, the wedge-shaped rod allows the controlled introduction of both clockwise and counterclockwise torque around the vertical axis of the root to induce dislodgment from the natural socket seating, before the subsequent vertical removal of the root.

Priority:

Inventor: WEATHERS ARTHUR KITCHINGS [US]


Application No.: US20090099233A1  Published: 16/Apr/2009

Title: HETEROARYL AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS

Applicant/Assignee:

Application No.: 12/249230   Filing Date: 10/Oct/2008

Abstract:

The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Priority: US20070979258P Applic. Date: 2007-10-11

Inventor: JOSHI PRAMOD [US]; KRENITSKY PAUL [US]; TERMIN ANDREAS [US]; WILSON DEAN [US]


Application No.: US20090101164A1  Published: 23/Apr/2009

Title: MINT AND FLOSS ORAL-PRODUCT CONTAINER

Applicant/Assignee:

Application No.: 12/175677   Filing Date: 18/Jul/2008

Abstract:

An oral-product container is disclosed that includes a plurality of breath fresheners contained therein for breath freshening purposes. The container includes an elongated dental instrument (e.g., a toothpick or dental floss) for hygiene improving purposes contained within the container. In the preferred embodiments, the container has a dispensing opening for dispensing breath fresheners. The container preferably has a laterally movable cover mounted to move between a closed state in which the cover covers both the dispensing opening and the elongated dental instrument and an open state in which the cover exposes both the dispensing opening and the elongated dental instrument.

Priority: US20070950495P Applic. Date: 2007-07-18; US20070950497P Applic. Date: 2007-07-18

Inventor: BERG ROBERT ISAAC [US]; HOELTCEN TOM [CA]


Application No.: US20090101172A1  Published: 23/Apr/2009

Title: SYSTEM AND AUTOMATIC METHOD FOR EXTRACTION OF GASEOUS ATMOSPHERIC CONTAMINANTS WITH TOXIC PROPERTIES, WHICH ARE RETAINED IN POLYURETHANE FOAM (PUF) FILTERS

Applicant/Assignee:

Application No.: 12/293123   Filing Date: 15/Mar/2007

Abstract:

The present invention provides a system and method for automatic extraction of gaseous atmospheric contaminants (for example HAPs and PCBs) with toxic properties, which are retained in polyurethane foam filters (PUF) that consists of: An automatic extraction device, which allows extracting chemicals compounds of interest using a sequence of organic solvents where the PUF must be immersed in, by means of a process of extraction based on compression and decompression cycles of the PUF

and A drying device which permits to dry the cleaned PUF, from the previous process, by means of sweeping the solvent with hot gaseous ultra pure N2, eliminating the solvent until achieving the dryness of the PUF.

Priority: CL20060000588 Applic. Date: 2006-03-16; WO2007ES70055 Applic. Date: 2007-03-15

Inventor: CERECEDA BALIC FRANCISCO [CL]; CERECEDA BALIC GABRIEL [CL]; DOROCHESI FERNANDOIS MARIO [CL]


Application No.: US20090101591A1  Published: 23/Apr/2009

Title: STORM DRAIN INLET PROTECTION DEVICE

Applicant/Assignee:

Application No.: 12/257162   Filing Date: 23/Oct/2008

Abstract:

A reusable protection device for a storm drain inlet includes a semi-permeable sleeve filled with a filter media. The protection device generally seats over a mouth to cover the storm drain inlet to allow passage of water runoff, but limit passage of sediment into the storm drain inlet. The sediment can be removed with a cleaning process for the removal of additional sediment from additional runoff water.

Priority: US20070982026P Applic. Date: 2007-10-23

Inventor: LEWIS CLINTON [US]


Application No.: US20090104128A1  Published: 23/Apr/2009

Title: Denture adhesive compositions with anti-ucler agents

Applicant/Assignee: ORAHEALTH CORPORATION

Application No.: 12/287646   Filing Date: 10/Oct/2008

Abstract:

The present invention relates to methods and compositions for reducing, inhibiting, and/or preventing denture sores, comprising a denture adhesive component and an effective amount of an anti-ulcer agent selected from the group consisting of Glycyrrhiza extract (GX), xylitol, and cobalamin. A denture wearer in need thereof applies the composition to the oral cavity and/or the denture prosthesis at a spot where a denture sore tends to form and thereafter secures the denture to the oral cavity.

Priority: US20070999516P Applic. Date: 2007-10-17

Inventor: HALEY JEFFREY T [US]


Application No.: US20090104474A1  Published: 23/Apr/2009

Title: FUNCTIONALIZED SUBSTRATES AND METHODS OF MAKING SAME

Applicant/Assignee: PRINCETON UNIVERSITY

Application No.: 12/253462   Filing Date: 17/Oct/2008

Abstract:

Polymer substrates including adhesion layers for activating the surface of the substrate are provided, thereby allowing the substrate to react with organic, inorganic, metallic and/or organometallic materials. The surface of the polymer substrate is coated with a metal oxide layer that is subjected to conditions adequate to form an oxide adhesion layer. Combining deposition techniques for formation of functionalized polymer surfaces with photolithographic techniques enables spatial control of RGD presentation at the polymer surfaces are achieved with sub-cellular resolution. Surface patterning enables control of cell adhesion location at the surface of the polymer and influences cell shape. Metallization of polymers as described herein provides a means to prepare metal-based electrical circuitry on a variety of flexible substrates.

Priority: US20070960859P Applic. Date: 2007-10-17

Inventor: SCHWARTZ JEFFREY [US]; DENNES THOMAS J [US]


Application No.: US20090105117A1  Published: 23/Apr/2009

Title: STEM CELLS AND LIM MINERALIZATION PROTEINS

Applicant/Assignee: WARSAW ORTHOPEDIC, INC

Application No.: 11/875267   Filing Date: 19/Oct/2007

Abstract:

Methods of changing a phenotype of a cell are provided. The methods comprise increasing an amount of an amino acid sequence which is at least 70% identical to an amino acid sequence encoding an LMP protein or a fragment thereof in a cell. The cells may be contacted by either a composition comprising a nucleic acid sequence encoding the amino acid sequence which is at least 70% identical to the amino acid sequence encoding an LMP or its fragment or by a composition comprising acid sequence which is at least 70% identical to the amino acid sequence encoding an LMP or its fragment or any combination thereof. The cells may be contacted either in vivo or ex-vivo.

Priority:

Inventor: MARX JEFFREY C [US]; MCKAY WILLIAM F [US]; DRAPEAU SUSAN J [US]


Application No.: US20090105262A1  Published: 23/Apr/2009

Title: Bridged polycyclic compound based compositions for coating oral surfaces in humans

Applicant/Assignee:

Application No.: 12/228263   Filing Date: 11/Aug/2008

Abstract:

A pharmaceutically active agent, a pharmaceutically active agent carrier and method of use thereof are described. In some embodiments, a system may include a composition. The composition may include one or more bridged polycyclic compounds. At least one of the bridged polycyclic compounds may include at least two cyclic groups, and at least two pharmaceutically active agents may be associated with the bridged polycyclic compound. In some embodiments, one or more bridged polycyclic compounds may be applied to an oral surface of a human such that an oral malady may be inhibited and/or ameliorated.

Priority: US20070964312P Applic. Date: 2007-08-10; US20070965154P Applic. Date: 2007-08-17; US20080029332P Applic. Date: 2008-02-16; US20080074488P Applic. Date: 2008-06-20

Inventor: WHITEFORD JEFFERY A [US]


Application No.: US20090105271A1  Published: 23/Apr/2009

Title: PYRIDYL SULFONAMIDES AS MODULATORS OF ION CHANNELS

Applicant/Assignee:

Application No.: 12/212063   Filing Date: 17/Sep/2008

Abstract:

The present invention relates to pyridyl sulfonamide derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Priority: US20070994423P Applic. Date: 2007-09-19

Inventor: MARTINBOROUGH ESTHER [US]; ZIMMERMANN NICOLE [US]; NEUBERT TIMOTHY [US]; HAMPTON TARA [US]


Application No.: US20090105352A1  Published: 23/Apr/2009

Title: FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE

Applicant/Assignee: BEZWADA BIOMEDICAL, LLC

Application No.: 12/212233   Filing Date: 17/Sep/2008

Abstract:

This invention relates to the discovery of functionalized triclosan monomers and oligomers that, when incorporated into a substrate of, or applied as part of a coating to, medical devices and/or consumer products may extend the duration of antimicrobial properties to the medical devices and/or consumer products.

Priority: US20070975374P Applic. Date: 2007-09-26

Inventor: BEZWADA RAO S [US]


Application No.: US20090105361A1  Published: 23/Apr/2009

Title: Camphorquinone Derivative Having Acylphosphine Oxide Group, Photopolymerization Catalyst And Photo/Chemical Polymerization Catalyst Containing The Same And Hardenable Composition Contaning The Same

Applicant/Assignee: KABUSHIKI KAISHA SHOFU

Application No.: 12/225070   Filing Date: 13/Mar/2006

Abstract:

A compound that exhibits excellent color tone stability and physical properties as well as excellent photopolymerization activity over a wide region from near-ultraviolet to visible region, permitting relaxed operation under ambient light, so that wide application can be found in the dental field and photopolymerization industry

and a relevant photopolymerization initiator and hardenable composition. In particular, there is provided a novel camphorquinone derivative having an acylphosphine oxide group [-(C-O)-(P-O)<] in each molecule.

Further, there is provided a photopolymerization initiator comprising the camphorquinone derivative having an acrylphosphine oxide group [-(C-O)-(P-O)<] in each molecule as an indispensable component, loaded with at least one member selected from among a polymerization accelerator, a photoacid generator, a photosensitizer and a (bis)acylphosphine oxide, and provided a hardenable composition comprising the initiator. The thus provided photopolymerization initiator and hardenable composition exhibit excellent color tone stability and physical properties as well as excellent photopolymeritzaion activity over an ultraviolet and visible wide wavelength region, permitting relaxed operation under ambient light, so that wide application can be found in the dental field and photopolymerization industry.

Priority: WO2006JP304911 Applic. Date: 2006-03-13

Inventor: IKEMURA KUNIO [JP]; ICHIZAWA KENSUKE [JP]; JOGETSU YOSHIYUKI [JP]


Application No.: US20090105368A1  Published: 23/Apr/2009

Title: TIME-CONTROLLED INTRAORAL FILM FORMER SYSTEM FOR INTRAORAL USE

Applicant/Assignee: BISCO, INC

Application No.: 12/254591   Filing Date: 20/Oct/2008

Abstract:

A water soluble polymer or biodegradable polymer operable to act as a release or separator between a prepared and sealed dentin surface and a temporary restoration.

Priority: US20070981392P Applic. Date: 2007-10-19

Inventor: SUH BYOUNG I [US]; LEE JIN WHAN [US]


Application No.: US20090105370A1  Published: 23/Apr/2009

Title: Materials leading to improved dental composites and dental composites made therefrom

Applicant/Assignee:

Application No.: 11/974772   Filing Date: 16/Oct/2007

Abstract:

Provided herein are uncured dental composites suitable for, among other things, filling cavities in teeth.

Priority: US20060852528P Applic. Date: 2006-10-18

Inventor: ANTON DOUGLAS ROBERT [US]; JAYCOX GARY DELMAR [US]; HUANG YONGQING [US]


Application No.: US20090107494A1  Published: 30/Apr/2009

Title: SYSTEMS, METHODS AND APPARATUS FOR RESPIRATORY SUPPORT OF A PATIENT

Applicant/Assignee: BREATHE TECHNOLOGIES, INC

Application No.: 11/523519   Filing Date: 20/Sep/2006

Abstract:

Spontaneous respiration is detected by sensors. An additional amount of oxygen is administered to the lungs via a jet gas current at the end of an inhalation procedure. Breathing volume, absorption of oxygen during inhalation, and clearance of carbon dioxide during exhalation are improved. If required, the exhalation procedure of the patient can be arrested or slowed by a countercurrent to avoid a collapse of the respiration paths. An apparatus including an oxygen pump can be connected to an oxygen source and includes a tracheal prosthesis that can be connected via a catheter. The respiration detections sensors are connected to a control unit for activating the oxygen pump. The tracheal prosthesis includes a tubular support body with a connection for the catheter, and the sensors are associated with the support body.

The tracheal prosthesis and jet catheter are dimensioned so the patient can freely breathe and speak without restriction.

Priority: US20050718318P Applic. Date: 2005-09-20

Inventor: FREITAG LUTZ [DE]; KAPUST GREGORY [US]; WONDKA ANTHONY [US]


Application No.: US20090108505A1  Published: 30/Apr/2009

Title: BLOW MOULDING MACHINE FOR PLASTIC CONTAINERS, AND METHOD FOR CONTROLLING IT

Applicant/Assignee: KRONES AG

Application No.: 12/255986   Filing Date: 22/Oct/2008

Abstract:

The invention relates to an apparatus and method for producing containers. The apparatus comprises at least one heating unit which heats preforms

at least one blow moulding unit which expands heated preforms to form containers

at least one sensor device which outputs at least one measured parameter representative of a physical state of the preforms or containers

wherein at least two control parameters of the heating unit or of the blow moulding unit can be varied

and an adjusting unit which is configured in such a way that it adjusts the control parameters as a function of the measured parameter. According to the invention, the adjusting unit comprises an associating device which associates control parameters with predefined measured parameters in a manner that is freely predefinable.

Priority: DE200710050908 Applic. Date: 2007-10-23; DE200810034934 Applic. Date: 2008-07-26

Inventor: STEINER ANDREAS [DE]


Application No.: US20090108635A1  Published: 30/Apr/2009

Title: Roller Blind Arrangement With An Improved Guiding System

Applicant/Assignee:

Application No.: 11/994178   Filing Date: 30/Jun/2006

Abstract:

The invention relates to a roller blind arrangement, especially for motor vehicles, for covering a roof opening (2), said arrangement comprising a roller blind strip (5) which can be wound up and down by means of a winding shaft (4). At least one deviating means (10) is used for influencing the course of the roller blind strip (5) in the direction of displacement thereof, the at least one deviating means (10) being arranged at a fixed distance from the winding shaft in the longitudinal direction of the vehicle.

Priority: WO2006DE01138 Applic. Date: 2006-06-30; DE200510030843 Applic. Date: 2005-07-01

Inventor: WINGEN BERNHARD [DE]


Application No.: US20090110637A1  Published: 30/Apr/2009

Title: LMP and Regulation of Tissue Growth

Applicant/Assignee: WARSAW ORTHOPEDIC, INC

Application No.: 11/924960   Filing Date: 26/Oct/2007

Abstract:

Novel methods are provided for changing cell phenotype, comprising a method of changing a phenotype of a target cell comprising: increasing an amount of an amino acid sequence in a source cell, wherein the source cell is located within a volume of a media and wherein the amino acid sequence is selected from the group consisting of LMP-1 protein, an LMP-2 protein, an LMP-3 protein, an LMP-1s protein, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 or combination thereof

collecting at least a portion of the volume of the media

and contacting the target cell with at least the portion of the media.

Priority:

Inventor: MARX JEFFREY C [US]; MCKAY WILLIAM F [US]; DRAPEAU SUSAN J [US]


Application No.: US20090110717A1  Published: 30/Apr/2009

Title: TRANSMUCOSAL COMPOSITION

Applicant/Assignee:

Application No.: 12/297486   Filing Date: 25/Apr/2007

Abstract:

The invention provides a composition for delivering active agents through transmucosal administration, more particularly through the buccal mucosa. The composition is a unique transmucosal disk (10) which has two compartments (14) and (18)

the compartments consist of at least one active agent and at least one mucoadhesive agent and both the compartments are adapted to be in contact with the mucosal membrane. The invention also provides for transmucosal administration of an active agent and method of treatment of diseases in a subject in need of such treatment.

Priority: IN2006MU00682 Applic. Date: 2006-05-02; WO2007IN00164 Applic. Date: 2007-04-25

Inventor: SINGH AMARJIT [IN]; SINGH SARABJIT [IN]; PUTHLI SHIVANAND [IN]


Application No.: US20090110756A1  Published: 30/Apr/2009

Title: Methods and Compositions Related to PLUNC Surfactant Polypeptides

Applicant/Assignee:

Application No.: 11/934581   Filing Date: 02/Nov/2007

Abstract:

Embodiments include compositions and methods for lower the surface tension of a liquid-air interface by contacting such interface with all or part of a PLUNC polypeptide.

Priority: US20060864062P Applic. Date: 2006-11-02

Inventor: MCCRAY JR PAUL B [US]; GAKHAR LOKESH [US]; MALLAMPALLI RAMA K [US]; RAMASWAMY SUBRAMANIAN [US]; BARTLETT JENNIFER [US]


Application No.: US20090111342A1  Published: 30/Apr/2009

Title: FLOTATION AID

Applicant/Assignee:

Application No.: 12/258445   Filing Date: 27/Oct/2008

Abstract:

A flotation aid which has an inflation unit comprising an inflatable bladder and a gas container assembly including a capsule containing a compressed gas for inflating the bladder and having a valve through which gas may be released into the bladder, the gas container assembly being located substantially within the bladder and actuating means actuable externally of the bladder for actuating the valve to allow release of gas from the capsule into the bladder to inflate the bladder. In one form, the inflation unit is housed within a two-part longitudinally split casing, the parts of the casing being interconnected but being separated upon and by inflation of the bladder to release the bladder. In another form, the floatation aid is incorporated in pants or other article of clothing being located in a pocket and secured to the pants or article of clothing.

Priority: AU20070905953 Applic. Date: 2007-10-31

Inventor: HANSON JOHN [AU]


Application No.: US20090111734A1  Published: 30/Apr/2009

Title: COMPOSITIONS AND METHODS FOR PROMOTING HEMOSTASIS AND OTHER PHYSIOLOGICAL ACTIVITIES

Applicant/Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY VERSITECH LIMITED

Application No.: 12/199670   Filing Date: 27/Aug/2008

Abstract:

Compositions that include nanoscale structured materials or precursors thereof (e.g., self-assembling peptides) are described. The compositions can include other substances (e.g., a vasoconstrictor). Also described are methods for using the compositions to promote hemostasis, to protect the skin or wounds from contamination, to decontaiminate a site upon removal of previously applied compositions that provided a protective coating, and to inhibit the movement of bodily substances other than blood. The compositions are also useful in isolating tissue, removing tissue, preserving tissue (for, e.g., subsequent transplantation or reattachment), and as bulking, stabilizing or hydrating agents. Medical devices that include the compositions (e.g., a stent or catheter), bandages or other wound dressings, sutures, and kits that include the compositions are also described.

Priority: US2006-411745 Applic. Date: 2006-04-25; US20050674612P Applic. Date: 2005-04-25; US20060758827P Applic. Date: 2006-01-13

Inventor: ELLIS-BEHNKE RUTLEDGE [US]; ZHANG SHUGUANG [US]; SCHNEIDER GERALD [US]; SO KWOK-FAI [CN]; TAY DAVID [CN]; LIANG YU-XIANG [CN]


Application No.: US20090111841A1  Published: 30/Apr/2009

Title: Novel 3,9-Diaza-Spiro[5,5]Undecane Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee:

Application No.: 11/922931   Filing Date: 28/Jun/2006

Abstract:

This invention relates to novel 3,9-diaza-spiro[5.5]undecane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000960 Applic. Date: 2005-06-28; US20050694678P Applic. Date: 2005-06-29; WO2006EP63631 Applic. Date: 2006-06-28

Inventor: ERIKSEN BIRGITTE L [DK]; PETERS DAN [SE]; NIELSEN ELSEBET OSTERGAARD [DK]; REDROBE JOHN PAUL [DK]


Application No.: US20090111874A1  Published: 30/Apr/2009

Title: Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof

Applicant/Assignee: OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES

Application No.: 11/886965   Filing Date: 24/Mar/2006

Abstract:

The present invention relates to novel phenyl-N-acyl derivatives of biogenic amines and amino acids of general formula (I) as cyclooxynease inhibitors, possessing analgetic and anti-inflammatory properties and devoid of side effects in particular ulcerogeneity and pro-spasmodic actions, as well as capability to potentiate effect of other analgetics, and possessing in addition antihypoxic, antidepressant and anti-Parkinsonistic action

as well as to the processes for the preparation novel and known phenyl-N-acyl derivatives of biogenic amines, to a pharmaceutical composition and to an agent comprising compounds of general formula (I) as well as to use thereof and a method of treating.

Priority: RU20050108492 Applic. Date: 2005-03-25; WO2006RU00139 Applic. Date: 2006-03-24

Inventor: NEBOLSIN VLADIMIR EVGENIEVICH [RU]; KROMOVA TATYANA ALEXANDROVNA [RU]; ZHELTUKHINA GALINA ALEXANDROVNA [RU]; KOVALEVA VIOLETTA LEONIDOVNA [RU]


Application No.: US20090112157A1  Published: 30/Apr/2009

Title: MIXING DEVICE INCLUDING A PLUNGING MIXING MEMBER FOR USE WITH A SYRINGE

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 12/258746   Filing Date: 27/Oct/2008

Abstract:

Mixing devices used with a syringe or syringe system and related systems for mixing dissimilar components contained therein. The devices and systems include a hollow elongate handle having a proximal end, a distal delivery end, and a delivery passageway therethrough. A mixing member is disposed at or near the proximal end of the hollow elongate handle, which mixing member and a portion of the handle are axially slidable within a syringe barrel during use. The user may push and pull the distal end of the handle, causing corresponding axial movement of the mixing member within the syringe barrel. The devices and systems may be used to homogenously mix difficult to mix two part compositions, as well as single part compositions which include components that may tend to separate over time (e.g., a fluoride varnish composition).

Priority: US20070984078P Applic. Date: 2007-10-31

Inventor: JESSOP NEIL T [US]


Application No.: US20090113936A1  Published: 07/May/2009

Title: Dental Glass

Applicant/Assignee: IVOCLAR VIVADENT AG EMPA DUEBENDORF EMPA DUBENDORF

Application No.: 12/083821   Filing Date: 25/Sep/2006

Abstract:

The present invention relates to a dental glass containing 50 to 70 wt. % of SiO2, 5 to 18 wt. % of Al2O3, 6.1 to 30 wt. % of MgO, 1 to 15 wt. % of La2O3, 1 to 15 wt. % of WO3, 0.1 to 8 wt. % of ZrO2, and optionally further oxides except for the oxides of Sr, Ba or alkali metals, wherein the stated quantities in total add up to 100 wt. %.

Priority: DE200510051387 Applic. Date: 2005-10-27; WO2006EP66702 Applic. Date: 2006-09-25

Inventor: RITZBERGER CHRISTIAN [AT]; RHEINBERGER VOLKER [LI]; APEL ELKE [CH]; BURTSCHER PETER [AU]; HOLAND WOLFRAM [LI]; GRAULE THOMAS [CH]; ZURCHER SIMONE [CH]; VITAL ANDRI [CH]


Application No.: US20090114228A1  Published: 07/May/2009

Title: Disposable outdoors mask and method of use

Applicant/Assignee:

Application No.: 12/153606   Filing Date: 21/May/2008

Abstract:

A mask designed to be worn to cover the mouth of a user comprises an inner and exterior layers, with an odor adsorbing layer and a filter layer disposed between the inner and exterior layer. The filter layer is positioned between the inner layer and odor adsorbing layer to prevent or minimize entry of unwanted particulate matter into the user's mouth. Once the mask is used to its fullest, it can be thrown away since it is constructed to be sufficiently low in cost so that it can be disposed and another one used the next time odor and particulate filtering is needed.

Priority: US20070984575P Applic. Date: 2007-11-01

Inventor: KIRSCHNER GARRY WILLIAM [CA]


Application No.: US20090114229A1  Published: 07/May/2009

Title: Mouth Seal Assembly for Nasal Mask System

Applicant/Assignee: RESMED LTD

Application No.: 11/988931   Filing Date: 28/Aug/2006

Abstract:

A mouth seal assembly for use with a nasal mask system includes a mouth seal adapted to form a seal with the patient's mouth. The mouth seal is substantially independent from a supply of pressurized air from the nasal mask system. An anti-asphyxia valve may be provided to either the mouth seal over the patient's lips or the nasal mask system. A strap arrangement may support the mouth seal in a desired position on the patient's face in use.

Priority: US20050711669P Applic. Date: 2005-08-29; WO2006AU01246 Applic. Date: 2006-08-28

Inventor: FRATER ROBERT HENRY [AU]; PEAKE GREGORY ROBERT [AU]


Application No.: US20090114243A1  Published: 07/May/2009

Title: Plastic disposable right angle tooth cleaner

Applicant/Assignee:

Application No.: 12/228638   Filing Date: 15/Aug/2008

Abstract:

A molded plastic toothpick device that includes a round handle with a right angle tapered tip. The cylindrical handle allows rotating the device in the finger to correctly insert the taper tip in spaces between both the upper and lower teeth. The objective of the invention is to enable individuals to effectively clean between every tooth easier than dental floss or a straight toothpick. Also you massage the gums between each tooth. This will help keep the gums healthy. It works great in the posterior area. There is no product on the market now that does this. The toothpick can be produced at relatively low cost from plastic.

Priority: US20070969928P Applic. Date: 2007-09-04

Inventor: MCNEIL DON [US]


Application No.: US20090117057A1  Published: 07/May/2009

Title: Grape Polyphenolics for Platelet and Bacterial Control

Applicant/Assignee: SHANBROM TECHNOLOGIES, LLC

Application No.: 11/935926   Filing Date: 06/Nov/2007

Abstract:

Special extracts of grape berries and Gogi berries can be prepared by exposing fruit juices or preparations to an insoluble binding resin which is then extracted with soluble polyvinylpyrollidone. Grape and Goji extracts made in this way can be used to inhibit or control platelet aggregation. Grape extract has exceptional antibacterial properties and can be used to control oral bacteria and to control MRSA (Methicillin-resistant Staphylococcus aureus). The combination of control of platelet aggregation and antibacterial properties exhibited by the grape-extract allows it to be used to significantly extend the life of isolated platelets. When added to solutions of isolated platelets, the grape extract prevents bacterial growth and prevents deterioration of the platelets through activation. This treatment extends the usable life of platelet concentrates to at least ten days.

Priority:

Inventor: SHANBROM EDWARD [US]


Application No.: US20090117058A1  Published: 07/May/2009

Title: Toothpaste composition for tooth whitening

Applicant/Assignee:

Application No.: 11/989283   Filing Date: 13/Jun/2006

Abstract:

The present invention relates to a toothpaste composition having tooth whitening effect, and more specifically, to a toothpaste composition which contains hydrogen peroxide, as peroxide releasing oxygen free radicals for the whitening effect, and silica with reduced contents of metal ions, to overcome the difficulty in long-term storage due to the release of oxygen free radicals resulting from degradation of peroxide by metal ions released from other components in the composition, and unsatisfactory tooth whitening effect. The toothpaste composition of the present invention does not release oxygen free radicals during storage, and so has excellent preservativeness and sustained tooth whitening effect.

Priority: KR20050067140 Applic. Date: 2005-07-25; WO2006KR02257 Applic. Date: 2006-06-13

Inventor: LEE BYUNG-RYEUL [KR]; KANG KYE-HONG [KR]; KIM DAE-KYEONG [KR]; KIM KI-JUNG [KR]


Application No.: US20090117059A1  Published: 07/May/2009

Title: COMPOSITIONS AND METHODS OF USE THEREOF, FOR THE TREATMENT OF ORAL PAIN, COMPRISING CLOVES OR EXTRACTS THEREOF IN COMBINATION WITH A STEROID

Applicant/Assignee:

Application No.: 12/184083   Filing Date: 31/Jul/2008

Abstract:

Provided are compositions for delivery to an individual's mouth to provide immediate as well as long-lasting pain relief, particularly after tooth extraction or other dental procedure, which include clove, a clove extract or eugenol, and optionally a steroid and other additives including an antibiotic. Kits and systems for delivery of the composition to provide sustained pain relief are also provided.

Priority: US20070007512P Applic. Date: 2007-08-03; US20080075724P Applic. Date: 2008-06-25

Inventor: ORONSKY BRYAN T [US]; ORONSKY NEIL C [US]


Application No.: US20090117504A1  Published: 07/May/2009

Title: Furnace assembly

Applicant/Assignee:

Application No.: 12/291357   Filing Date: 07/Nov/2008

Abstract:

The invention relates to a furnace assembly for dental technology, in particular for ceramic dental compositions, comprising a display device associated with a furnace assembly (10), which may be designed in the manner of a touchscreen, and comprising a control device, which has a data interface by way of which data for controlling the furnace assembly and/or image data (in the form of static images or moving images) can be transmitted. The control device has a packet module, in particular an EDGE, GSM, GRPS and/or UMTS module, by way of which control data and/or image data for presentation on the display device can be transmitted in the form of packets.

Priority: DE200710053071 Applic. Date: 2007-11-07

Inventor: GRUNENFELDER ROBERT [LI]


Application No.: US20090117513A1  Published: 07/May/2009

Title: CONCURRENT TREATMENT OF ORAL MALADIES USING DIRECT CURRENT ELECTRICITY

Applicant/Assignee:

Application No.: 12/205062   Filing Date: 05/Sep/2008

Abstract:

A method and apparatus for the concurrent treatment of multiple oral diseases and defects while promoting general oral hygiene utilizing direct current electricity. Electrodes are used to deliver a direct current to the gingival tissues of a mouth in order to achieve a number of therapeutic, prophylactic, and regenerative benefits. These benefits include killing oral microbes, increasing oral vasodilation, improving oral blood circulation, reversing oral bone resorption, promoting oral osteogenesis, treating gum recession, and fostering gingival regeneration. Other benefits include the treatment of gingivitis, perdiodontitis, and oral malodor while also promoting general oral hygiene.

Priority: US2007-850661 Applic. Date: 2007-09-05

Inventor: NEMEH ISSAM [US]; SZATKOWSKI GEORGE NICHOLAS [US]


Application No.: US20090117515A1  Published: 07/May/2009

Title: INTERPROXIMAL MARKING STRAND

Applicant/Assignee:

Application No.: 11/935521   Filing Date: 06/Nov/2007

Abstract:

A method and device for marking a natural tooth/bridge, crown or any dental restoration interface to mark high spots on said bridge or crown to be removed during the fitting process using a fiber or filament strand impregnated or otherwise treated with a visual indicating marker material. The marking device may include the use of handheld tool that includes at least one end having a wishbone shaped support for attaching the fiber or filament strand impregnated with the marker material between the wishbone support or having a tool having both ends with wishbone supports, both ends for supporting one or more filaments or strands of material that includes visual markers.

Priority:

Inventor: RESK RICHARD [US]


Application No.: US20090118179A1  Published: 07/May/2009

Title: Therapeutic Agent for Dentin-Pulp Complex Regeneration

Applicant/Assignee: OSAKA UNIVERSITY KAKEN PHARMACEUTICAL CO., LTD

Application No.: 12/083734   Filing Date: 19/Oct/2006

Abstract:

The present invention provides a therapeutic agent for regenerating a dentin-pulp complex, containing a basic fibroblast growth factor and/or a homolog thereof as an active ingredient. The present invention also provides a pulp-capping agent containing a basic fibroblast growth factor and/or a homolog thereof as an active ingredient.

Priority: JP20050305076 Applic. Date: 2005-10-19; WO2006JP321308 Applic. Date: 2006-10-19

Inventor: MURAKAMI SHINYA [JP]; SHIMABUKURO YOSHIO [JP]


Application No.: US20090118275A1  Published: 07/May/2009

Title: THIAZOLOPYRIMIDINE P13K INHIBITOR COMPOUNDS AND METHODS OF USE

Applicant/Assignee: GENENTECH, INC F. HOFFMANN - LA ROCHE AG

Application No.: 12/236317   Filing Date: 23/Sep/2008

Abstract:

Compounds of Formulas Ia and Ib, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula Ia and Ib for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Priority: US20070974708P Applic. Date: 2007-09-24

Inventor: CASTANEDO GEORGETTE M [US]; GUNZNER JANET L [US]; MALESKY KIMBERLY [US]; MATHIEU SIMON [US]; OLIVERO ALAN G [US]; SUTHERLIN DANIEL P [US]; WANG SHUMEI [US]; ZHU BING-YAN [US]; CHUCKOWREE IRINA [GB]; FOLKES ADRIAN [GB]; OXENFORD SALLY [GB]; WAN NAN CHI [GB]


Application No.: US20090118276A1  Published: 07/May/2009

Title: THIENOPYRIMIDINES, THIENOPYRIDINES, AND PYRROLOPYRIMIDINES AS B-RAF INHIBITORS

Applicant/Assignee: WYETH

Application No.: 12/262622   Filing Date: 31/Oct/2008

Abstract:

The present invention relates to compounds of formula la: and pharmaceutically acceptable salts thereof. The thieno[3,2-d]pyrimidine, thieno[2,3-d]pyrimidine, thieno[3,2-b]pyridine, thieno[2,3-b]pyridine, and pyrrolo[2,3-d]pyrimidine compounds selectively inhibit B-Raf kinase activity and are useful for treating disorders mediated by B-Raf kinase, and for the treatment of cancer.

Priority: US20070984918P Applic. Date: 2007-11-02

Inventor: GOPALSAMY ARIAMALA [US]; SHI MENGXIAO [US]; BERGER DAN MAARTEN [US]; DUTIA MINU DHANJISHA [US]; TORRES NANCY [US]; HOPPER DARRIN WILLIAM [US]


Application No.: US20090118389A1  Published: 07/May/2009

Title: Hardenable dental compositions with low polymerization shrinkage

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/912950   Filing Date: 09/May/2006

Abstract:

The present invention features a hardenable dental composition that contains: (1) at least one cyclic allylic compound having at least one sulfur atom in the ring, and (2) at least one at least one ethylenically unsaturated compound, such as a substituted (meth)acryloyl compound. The compositions also typically comprise an initiator system, preferably a photoinitator system containing at least 0.08 wt-% of one or more photosensitizers.

Priority: US20050679265P Applic. Date: 2005-05-09; WO2006US17820 Applic. Date: 2006-05-09

Inventor: ABUELYAMAN AHMED S [US]; MITRA SUMITA B [US]; LEWANDOWSKI KEVIN M [US]; PLAUT DAVID J [US]; JONES TODD D [US]


Application No.: US20090119871A1  Published: 14/May/2009

Title: Electric vacuum head

Applicant/Assignee:

Application No.: 12/288260   Filing Date: 17/Oct/2008

Abstract:

An electric vacuum head for a vacuum cleaner has a housing, a cleaning device that can be driven by an electric motor disposed within the housing in a motor chamber, a vacuum mouth on the underside of the housing delimited by vacuum mouth edges, and a vacuum connector. The motor chamber has at least one air entry opening for entry of air to cool the electric motor, and at least one air exit opening. The air exit opening is disposed on the underside of the housing so that the cooling air that exits from the air exit opening during operation of the electric vacuum head enters into the vacuum mouth by way of at least one of the vacuum mouth edges.

Priority: EP20070022070 Applic. Date: 2007-11-14

Inventor: DILGER HORST [DE]; KAFFENBERGER DIETER [DE]; LIND THOMAS [DE]; RIEHL KLAUS-DIETER [DE]; STEUDTNER HANS-JOACHIM [DE]


Application No.: US20090120242A1  Published: 14/May/2009

Title: Insulation stripping tool with displaceable knife carrier means

Applicant/Assignee: WEIDMUELLER INTERFACE GMBH & CO. KG

Application No.: 12/290558   Filing Date: 31/Oct/2008

Abstract:

A pliers-type insulation stripping tool includes a pair of blade holders that are removably connected with the pull rod that longitudinally displaces the blades relative to the handle shell when a severed length of insulation is stripped from the insulated conductor. A resilient ejector arrangement in provided for ejecting from the handle shell the length of stripped insulation. In order to permit use of the insulation stripping tool with insulated conductors of various sizes and diameters, a blade depth adjusting device is provided for adjusting the distance between at least one of the blade holders and the associated clamping jaw.

Priority: DE200720015348U Applic. Date: 2007-11-02

Inventor: STORM SIEGFRIED [DE]; HEGGEMANN CHRISTIAN [DE]; HETLAND DETLEV [DE]; HANNING GUENTER [DE]; KOESTER THOMAS [DE]; WEDLER ANDREAS [DE]


Application No.: US20090120454A1  Published: 14/May/2009

Title: Multi-Ribbed Dental Tape

Applicant/Assignee:

Application No.: 12/184067   Filing Date: 31/Jul/2008

Abstract:

The present invention includes monofilament dental tapes for removing plaque and/or food debris from interdental spaces of a mammal, which dental tapes have a core body with an aspect ratio of greater than about 5:1 and a first cleaning surface and a second cleaning surface opposite the first cleaning surface, where at least one of the first and second cleaning surfaces includes a plurality of ribs disposed along the length thereof, and where the ratio of the width of the dental tape to the thickness of the dental tape is from about 4:1 to about 25:1.

Priority: US2007-937025 Applic. Date: 2007-11-08

Inventor: OCHS HAROLD D [US]; KNUTZEN JOSEF V [US]; FOUGERE RICHARD J [US]; LEBOVSKY ALEXANDER [US]


Application No.: US20090120455A1  Published: 14/May/2009

Title: Multi-Ribbed Dental Tape

Applicant/Assignee:

Application No.: 11/937025   Filing Date: 08/Nov/2007

Abstract:

The present invention includes monofilament dental tapes for removing plaque and/or food debris from interdental spaces of a mammal, which dental tapes have a core body with an aspect ratio of greater than about 5:1 and a first cleaning surface and a second cleaning surface opposite the first cleaning surface, where at least one of the first and second cleaning surfaces includes a plurality of ribs disposed along the length thereof, and where the ratio of the width of the dental tape to the thickness of the dental tape is from about 4:1 to about 25:1.

Priority:

Inventor: OCHS HAROLD D [US]; KNUTZEN JOSEF V [US]; FOUGERE RICHARD J [US]; LOBOVSKY ALEXANDER [US]


Application No.: US20090120565A1  Published: 14/May/2009

Title: Temporary Facial Decal

Applicant/Assignee:

Application No.: 11/938698   Filing Date: 12/Nov/2007

Abstract:

A temporary facial decal comprising a mask-like substrate having apertures for the eyes and mouth and having a nose opening taken from the group of slit and aperture with the body of the mask having a transferable image thereon covered by a removable protective sheet that is removed from the decal which is then placed on the user's face using the provided apertures for alignment whereupon an agent, preferably water, is used to transfer the image onto the user's face.

Priority:

Inventor: MARSHALL DOUGLAS [US]


Application No.: US20090120814A1  Published: 14/May/2009

Title: Sanitary toothbrush holder

Applicant/Assignee:

Application No.: 11/983378   Filing Date: 08/Nov/2007

Abstract:

A toothbrush holder and sterilizer having a cylindrical body with an interior shoulder adjacent the upper end and a perforated bottom wall with an annular flange extending downwardly relative to the body. A fluid reservoir upstanding from the bottom wall, the reservoir being open at the top and having a plurality of annularly spaced openings spaced downwardly of the upper end of the reservoir. There is also an exterior shoulder adjacent the upper end of the reservoir in the same plane as the shoulder at the upper end of the body to support an annular disk having a plurality of spaced openings for reception of toothbrushes. A shallow cup is disposed on the flange on the bottom of the body for reception of condensed disinfectant or the like which will flow through the openings or perforations in the bottom wall. Any suitable disinfectant, antiseptic, germicide or the like in liquid form, is disposed in the reservoir and the fumes from the disinfectant pass upwardly and out of the upper end of the reservoir into the chamber where the bristled ends of the toothbrushes are disposed.

Priority:

Inventor: MILLER DENNIS BEACH [US]


Application No.: US20090120966A1  Published: 14/May/2009

Title: CONTAINER HAVING DELIVERY MECHANISM WITH SECURING CAP

Applicant/Assignee: PIBED LIMITED

Application No.: 12/357181   Filing Date: 21/Jan/2009

Abstract:

A container having a mechanism that delivers liquid from a container to a mouth and that moves between an extended position and a depressed position to deliver the contents of the container to the mouth and a removable securing cap that retains the mechanism in the depressed position.

Priority: US2007-981895 Applic. Date: 2007-11-01

Inventor: LIMBERT DEAN PHILIP [GB]


Application No.: US20090123217A1  Published: 14/May/2009

Title: DENTAL CLEANSER AND STAIN PREVENTION APPARATUS

Applicant/Assignee:

Application No.: 11/938167   Filing Date: 09/Nov/2007

Abstract:

Several embodiments of a dental cleanser and stain prevention apparatus for portable use are described. In each embodiment an apparatus for use in on-the-go dental cleansing is described. In one series of embodiments, disposable dental cleaning devices are described. In another series of embodiments, reusable and refillable dental cleaning devices are described. Packaging of various types is also disclosed for use in housing the dental cleanser and stain prevention apparatus.

Priority:

Inventor: ROSS KAREN L [US]


Application No.: US20090123393A1  Published: 14/May/2009

Title: Multiphase Toothpaste Composition

Applicant/Assignee:

Application No.: 11/883751   Filing Date: 12/Jan/2006

Abstract:

Multiphase toothpaste composition comprising a first phase disposed co-axially within a second, visually clear gel phase, the second phase comprising from 1 ppm to 100 ppm of a pigment.

Priority: IN2005MU00118 Applic. Date: 2005-02-04; IN2005KO00288 Applic. Date: 2005-04-08; WO2006EP00256 Applic. Date: 2006-01-12

Inventor: BIJLANI NAND SANMUKHDAS [IN]


Application No.: US20090123395A1  Published: 14/May/2009

Title: Flavour Compositions

Applicant/Assignee:

Application No.: 12/330624   Filing Date: 09/Dec/2008

Abstract:

Flavor compositions which reduce or prevent dental cavities based on the use of flavor materials found to inhibit the production of acid by micro-organisms in the oral cavity, e.g. lactic acid production from glucose by Streptococcus mutans. The compositions include at least two flavor materials from group (a) and at least one flavor material from group (b). Representative group (a) flavors are decanol, nonanol and cinnamic aldehyde while typical group (b) flavors are nonanal, citral and peppermint oil of material origin.

Priority: GB20030003676 Applic. Date: 2003-02-18; US2005-545746 Applic. Date: 2005-08-17; WO2004GB00515 Applic. Date: 2004-02-11

Inventor: BEHAN JOHN MARTIN [GB]; BRADSHAW DAVID JONATHAN [GB]; RICHARDS JONATHAN [GB]; MUNROE MICHAEL JOHN [GB]


Application No.: US20090123396A1  Published: 14/May/2009

Title: Anti-sensitivity,anti-caries, anti-staining, anti-plaque ultra-mild oral hygiene agent

Applicant/Assignee: RHODIA INC

Application No.: 12/319856   Filing Date: 13/Jan/2009

Abstract:

This invention relates to a composition useful as a dentifrice comprising a surfactant agent consisting essentially of monoalkyl and dialkyl phosphate esters, wherein the ratio of monoesters to diesters is greater than 1, and optionally an abrasive agent consisting essentially of siliceous materials.

Priority: US2004-783721 Applic. Date: 2004-02-20; US20030449128P Applic. Date: 2003-02-21

Inventor: REIERSON ROBERT LEE [US]; DOMKE TODD WILLIAM [US]


Application No.: US20090123464A1  Published: 14/May/2009

Title: Method for the potentiation of opioid analgesics effects on pain

Applicant/Assignee: LAY LINE GENOMICS S.P.A

Application No.: 11/921266   Filing Date: 23/Jun/2006

Abstract:

According to the invention there is provided use of an anti-TrkA antibody capable of inhibiting the binding between NGF and TrkA combined with at least one opioid analgesic for the preparation of a medicament for treating and/or preventing pain.

Priority: IT2005RM00332 Applic. Date: 2005-06-24; WO2006IT00488 Applic. Date: 2006-06-23

Inventor: PAVONE FLAMINIA [IT]; MARINELLI SARA [IT]; CATTANEO ANTONINO [IT]; UGOLINI GABRIELE [IT]


Application No.: US20090123623A1  Published: 14/May/2009

Title: Food dicer

Applicant/Assignee:

Application No.: 11/921412   Filing Date: 06/Jun/2006

Abstract:

A dicing tool having: a foodstuff holder for holding a block of foodstuff and a cutting base

the cutting base having: a rectangular framework for sliding the foodstuff holder therealong

a first part having an triangular shaped front edge, equally spaced triangular cutting blades being arranged in a triangular arrangement that follows the profile of the triangularly shaped front edge

a handle

a second part having a second upper surface and a right front edge and a left front edge arranged in a deep V shape, with continuous blades attached to the right and left front edges

wherein the second upper surface is always parallel to the first surface and can be slidingly reciprocated between an upper position and a lower position where the horizontal blade is substantially on a level with the first surface and the base of the triangular cutting blades.

Priority: US20050688720P Applic. Date: 2005-06-09; WO2006IL00652 Applic. Date: 2006-06-06

Inventor: TWEG EDWARD [IL]


Application No.: US20090123733A1  Published: 14/May/2009

Title: SUBSTRATE HAVING AN ELECTRON DONATING SURFACE WITH METAL PARTICLES COMPRISING PALLADIUM ON SAID SURFACE

Applicant/Assignee: BACTIGUARD AB

Application No.: 12/296429   Filing Date: 05/Apr/2007

Abstract:

There is disclosed a substrate with an electron donating surface, characterized in having metal particles on said surface, said metal particles comprising palladium and at least one metal selected from the group consisting of gold, ruthenium, rhodium, osmium, iridium, and platinum, wherein the amount of said metal particles is from about 0.001 to about 8 mug/cm2. Examples of coated objects include contact lenses, pacemakers, pacemaker electrodes, stents, dental implants, rupture nets, rupture mesh, blood centrifuge equipment, surgical instruments, gloves, blood bags, artificial heart valves, central venous catheters, peripheral venous catheters, vascular ports, haemodialysis equipment, peritoneal dialysis equipment, plasmapheresis devices, inhalation drug delivery devices, vascular grafts, arterial grafts, cardiac assist devices, wound dressings, intermittent catheters, ECG electrodes, peripheral stents, bone replacing implants, orthopaedic implants, orthopaedic devices, tissue replacing implants, intraocular lenses, sutures, needles, drug delivery devices, endotracheal tubes, shunts, drains, suction devices, hearing aid devices, urethral medical devices, and artificial blood vessels.

Priority: US20060790307P Applic. Date: 2006-04-07; WO2007SE50226 Applic. Date: 2007-04-05

Inventor: OHRLANDER MATTIAS [SE]; SODERVALL BILLY [SE]


Application No.: US20090123974A1  Published: 14/May/2009

Title: Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules

Applicant/Assignee:

Application No.: 12/082365   Filing Date: 09/Apr/2008

Abstract:

Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines.

Priority: US2007-706088 Applic. Date: 2007-02-13; US2003-658834 Applic. Date: 2003-09-08; US20030457135P Applic. Date: 2003-03-21; US20020409898P Applic. Date: 2002-09-09

Inventor: GANTIER RENE [FR]; VEGA MANUEL [FR]; DRITTANTI LILA [FR]; GUYON THIERRY [FR]


Application No.: US20090124556A1  Published: 14/May/2009

Title: Peptides Exhibiting Efficacies of Improvement in Skin Conditions or Treatment of Periodental Diseases

Applicant/Assignee:

Application No.: 12/083970   Filing Date: 24/Oct/2006

Abstract:

The present invention relates to a composition for improving a skin condition or treating a periodontal disease, which comprises as an active ingredient a basic fibroblast growth factor-derived peptide. The peptides of this invention exhibit superior efficacies and much better stability and skin permeation than natural-occurring bFGF. In these connections, the composition comprising the peptides of this invention can exhibit excellent efficacies on improvement in skin conditions and treatment of periodontal diseases. In addition, the peptides of this invention can be advantageously applied to pharmaceutical compositions, cosmetics, tooth-paste and compositions for mouth cleaning and caring.

Priority: KR20050100391 Applic. Date: 2005-10-24; WO2006KR04350 Applic. Date: 2006-10-24

Inventor: CHUNG YONG JI [KR]; KIM YOUNG DEUG [KR]; KIM CHUNG RYUL [KR]


Application No.: US20090124655A1  Published: 14/May/2009

Title: HETEROCYCLIC DERIVATIVES AS MODULATORS OF ION CHANNELS

Applicant/Assignee:

Application No.: 12/269109   Filing Date: 12/Nov/2008

Abstract:

The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Priority: US20070987490P Applic. Date: 2007-11-13

Inventor: STAMOS DEAN [US]; MARTINBOROUGH ESTHER [US]; ZIMMERMANN NICOLE [US]; NEUBERT TIMOTHY [US]; NUMA MEHDI MICHEL DJAMEL [US]; WHITNEY TARA [US]; HAMPTON TARA LEANNE [US]


Application No.: US20090124663A1  Published: 14/May/2009

Title: Novel n-phenyl-piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Applicant/Assignee: NEUROSEARCH A/S

Application No.: 11/921771   Filing Date: 07/Jun/2006

Abstract:

This invention relates to novel N-phenyl-piperidine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000836 Applic. Date: 2005-06-08; US20050688381P Applic. Date: 2005-06-08; WO2006EP62951 Applic. Date: 2006-06-07

Inventor: PETERS DAN [SE]; REDROBE JOHN PAUL [DK]; NIELSEN ELSEBET OSTERGAARD [DE]; BROWN DAVID TRISTAM [DK]


Application No.: US20090124666A1  Published: 14/May/2009

Title: TRPV1 ANTAGONISTS

Applicant/Assignee: ABBOTT LABORATORIES

Application No.: 12/256931   Filing Date: 23/Oct/2008

Abstract:

Compounds of formula (I) wherein R1, R2, R4, and W are defined in the description are TRPV 1 antagonists with CNS penetration. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

Priority: US20070982490P Applic. Date: 2007-10-25

Inventor: PERNER RICHARD J [US]; KOENIG JOHN R [US]; DIDOMENICO JR STANLEY [US]; BAYBURT EROL K [US]; DAANEN JEROME F [US]; GOMTSYAN ARTHUR [US]; KORT MICHAEL E [US]; KYM PHILIP R [US]; SCHMIDT ROBERT G [US]; VASUDEVAN ANIL [US]; VOIGHT ERIC [US]


Application No.: US20090124671A1  Published: 14/May/2009

Title: TRPV1 ANTAGONISTS

Applicant/Assignee: ABBOTT LABORATORIES

Application No.: 12/256924   Filing Date: 23/Oct/2008

Abstract:

The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4, R5, m, and n are defined in the specification are TRPV1 antagonists. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

Priority: US20070982200P Applic. Date: 2007-10-24

Inventor: GOMTSYAN ARTHUR R [US]; SCHMIDT ROBERT G [US]; BAYBURT EROL K [US]; DAANEN JEROME F [US]; KORT MICHAEL E [US]


Application No.: US20090124701A1  Published: 14/May/2009

Title: USE OF ALKAMIDES FOR MASKING AN UNPLEASANT FLAVOR

Applicant/Assignee: SYMRISE GMBH & CO. KG

Application No.: 12/266209   Filing Date: 06/Nov/2008

Abstract:

An individual alkamide and/or a mixture having two or more different alkamides, is disclosed for changing, masking or reducing the unpleasant flavor impression of an unpleasant-tasting substance or mixture of substances. The alkamide can be trans-pellitorine

cis-pellitorine

2Z,4Z- or 2Z,4E-decadienoic acid-N-isobutylamide

2E,4E-decadienoic acid-N-([2S]-2-methylbutyl)amide

2E,4E-decadienoic acid-N-([2R]-2-methylbutylamide)

2E,4Z-decadienoic acid-N-(2-methylbutyl)amide

achilleamide

sarmentine

2E- or 3E-decenoic acid-N-isobutylamide

3E-nonenoic acid-N-isobutylamide

spilanthol

homospilanthol

2E,6Z,8E-decatrienoic acid-N-([2R]-2-methylbutyl)amide

2E- or 2Z-decen-4-oic acid-N-isobutylamide

alpha-sanshool

alpha-hydroxysanshool

gamma-hydroxysanshool

gamma-hydroxysanshool

gamma-hydroxyisosanshool

gamma-dehydrosanshool

gamma-sanshool

bungeanool

isobungeanool

dihydrobungeanool

or tetrahydrobungeanool, or combinations thereof.

Priority: US20070986343P Applic. Date: 2007-11-08

Inventor: LANGER KATHRIN [DE]; LEY JAKOB [DE]; REINDERS GERALD [DE]; KINDEL GUNTER [DE]; KRAMMER GERHARD [DE]


Application No.: US20090126134A1  Published: 21/May/2009

Title: DENTAL TOOL CLEANER

Applicant/Assignee:

Application No.: 12/270681   Filing Date: 13/Nov/2008

Abstract:

A flexibly resilient porous body for cleaning dental tools is positioned in a receptacle. The receptacle may be conveniently held near a patient's mouth. The porous body includes surface grooves or cuts and is impregnated with an antibacterial solution. A dental tool which has been used to scrape the area around a patient's teeth and gums may be passed through the surface groove or cut in the porous body to remove any material and disinfect the tip of the dental tool.

Priority: US20070988480P Applic. Date: 2007-11-16

Inventor: WHIPPLE AMY A [US]; VOGL DANIEL J [US]


Application No.: US20090126534A1  Published: 21/May/2009

Title: Insulation stripping tool with striker means

Applicant/Assignee:

Application No.: 12/290479   Filing Date: 31/Oct/2008

Abstract:

An insulation stripping tool of the pliers-type includes an adjustable pull rod stop device for limiting the extent of travel of the longitudinally displaceable pull rod and the cutting and stripping blades connected thereto, thereby to produce only partial removal of a length of severed insulation layer from an insulated conductor. An adjustable conductor stop device is mounted on at least one of the cutting and stripping blade holders for limiting the extent to which the end of the insulated conductor is inserted into the open mouth of the stripping tool. A stationary scale is mounted on one of the handles adjacent the adjustable conductor stop device.

Priority: DE200720015347U Applic. Date: 2007-11-02

Inventor: STORM SIEGFRIED [DE]; HEGGEMANN CHRISTIAN [DE]; HETLAND DETLEV [DE]; HANNING GUENTER [DE]; KOESTER THOMAS [DE]; WEDLER ANDREAS [DE]


Application No.: US20090126742A1  Published: 21/May/2009

Title: Tongue grasping and restraining apparatus and methods

Applicant/Assignee:

Application No.: 11/986044   Filing Date: 17/Nov/2007

Abstract:

A tongue grasping and restraining device holds the tongue securely during sleep in order to minimize the risk of the tongue slipping back and blocking the throat, a condition known as obstructive sleep apnea. Plural tongue gripping projections are coupled to upper and lower supports. The projections engage and hold the tongue. The upper and lower supports are biased toward one another into a tongue engaging position. The upper support is coupled to the user's upper jaw, for example, to a denture, dental appliance or by upper teeth engaging mechanisms. The lower support can be hinged or otherwise joined to the upper support or can be separate therefrom. A tube and rod mechanism in one embodiment couples the upper and lower supports together. Exemplary methods of manufacturing tongue gripping projections are also disclosed.

Priority:

Inventor: SUMMER JOHN DAVID [US]


Application No.: US20090130030A1  Published: 21/May/2009

Title: Plural Activating Optical Change Toothpastes, Stimuli and Elements

Applicant/Assignee:

Application No.: 11/629113   Filing Date: 10/Jun/2005

Abstract:

Optical change toothpaste compositions (as well as methods for making and using the same), and methods for inducing and stimulating optical changes and associated elements for imparting optical changes are provided. Optical change toothpastes can possess a plurality of visual and reporting properties and find use in a variety of different applications.

Priority: US20040579060P Applic. Date: 2004-06-10; WO2005US20702 Applic. Date: 2005-06-10

Inventor: RIBI HANS O [US]


Application No.: US20090130031A1  Published: 21/May/2009

Title: Diamond, precious and semi-precious dust polishing agent for dental veneers and teeth

Applicant/Assignee:

Application No.: 12/288708   Filing Date: 22/Oct/2008

Abstract:

A diamond dust polishing agent for home use and professional use in the care of natural tooth enamel and dental veneers comprised of a quantity of diamond dust coated with a lubricant in conjunction with a paste for carrying the lubricant coated diamond dust, or other semi-precious, non-toxic abrasive dust, said diamond dust being of a size of approximately 500 nanometers or less to a size of approximately 5 nanometers. The size of the dust of both the diamond and the semi-precious stone may vary, depending on the degree of abrasiveness and the lubricant employed. The diamond dust (and semi-precious dust) polishing agent permits the user to maintain the polish and luster of the natural tooth enamel and veneer at home without adversely abrading or damaging the surface thereof.

Priority: US20070003552P Applic. Date: 2007-11-16

Inventor: HERMAN MICHAEL [US]


Application No.: US20090130032A1  Published: 21/May/2009

Title: DENTAL APPLIANCE CLEANSER

Applicant/Assignee:

Application No.: 12/293980   Filing Date: 22/Mar/2007

Abstract:

This invention relates to a dental appliance cleanser which is a metastable emulsion comprising about 50-99% w/w of an aqueous phase, about 1-50% w/w of a water immiscible oily phase, the oily phase having a combination of a one or more immiscible oils and one or more flavor oils. The dental appliance cleanser is applied to the dental appliance, outside the wearer's mouth, in the form of an aerated foam.

Priority: US20060785313P Applic. Date: 2006-03-23; WO2007US64596 Applic. Date: 2007-03-22

Inventor: BROGDEN KYLE N [US]; LECH STANLEY J [US]; MEHTA NARCSH I [US]; OTHS PHILIP J [US]


Application No.: US20090130048A1  Published: 21/May/2009

Title: Topical Composition for Treating Pain

Applicant/Assignee:

Application No.: 11/942409   Filing Date: 19/Nov/2007

Abstract:

Topical compositions having as the active ingredient a hydrophilic material, such as a polyalkylene oxide homopolymer or copolymer, and methods of use, have been developed for the amelioration or prevention of pain or the sequelae of pain. The composition may be in the form of a cream, gel, lotion, spray, foam, paste, patch, suspension or dispersion. In the preferred embodiment, the formulation is a gel. The composition may contain a penetration enhancer, most preferably one with membrane disruptive properties. In one embodiment, the compositions are incorporated onto or into disposables such as hemorrhoid wipes, gauze, sponge, bandages, and wraps

mouth guards, dental trays

needles or catheters

adult diapers

gloves, socks or wrist bands, for ease of application. The composition is applied topically to a site at or adjacent to a painful region. The composition is reapplied as necessary. Pain relief is typically obtained within minutes and lasts for periods of variable duration ranging from minutes to several hours and even, in some cases, days. The composition is variably effective to treat visceral, somatic and neuropathic pain both acute and chronic as well as muscle pain and stiffness and joint pain and stiffness.

Priority:

Inventor: ORONSKY BRYAN TODD [US]; ORONSKY NEIL CHARLES [US]; ORONSKY ARNOLD L [US]


Application No.: US20090130068A1  Published: 21/May/2009

Title: Oral Tissue Regeneration and Repair

Applicant/Assignee:

Application No.: 12/282326   Filing Date: 05/Mar/2007

Abstract:

A method for treating an oral condition of a subject by grafting cultured tissue constructs to the oral tissue. The cultured tissue constructs comprise cultured cells and endogenously produced extracellular matrix components without the requirement of exogenous matrix components or network support or scaffold members. Some tissue constructs of the invention are comprised of multiple cell layers or more than one cell type. The tissue constructs of the invention have morphological features and functions similar to tissues their cells are derived and their strength makes them easily handleable. Preferred cultured tissue constructs of the invention comprise cells derived from human tissue.

Priority: US20060779050P Applic. Date: 2006-03-03; WO2007US63301 Applic. Date: 2007-03-05

Inventor: EKLUND DARIO C [US]


Application No.: US20090130113A1  Published: 21/May/2009

Title: Compositions and methods for use for antibodies against sclerostin

Applicant/Assignee:

Application No.: 12/249050   Filing Date: 10/Oct/2008

Abstract:

The present invention relates to antibodies against sclerostin and compositions and methods of use for said antibodies to treat disease related to bone abnormalities such as osteoporosis. An embodiment of the invention herein provides an antibody or a functional protein comprising an antigen-binding portion of said antibody for a target in sclerostin polypeptide, characterized in that the antibody or functional protein specifically binds to sclerostin polypeptide and can increase at least one of bone formation, bone mineral density, bone mineral content, bone mass, bone quality and bone strength in a mammal.

Priority: EP20070118414 Applic. Date: 2007-10-12; EP20080151911 Applic. Date: 2008-02-25; EP20080161342 Applic. Date: 2008-07-29

Inventor: KNEISSEL MICHAELA [CH]; HALLEUX CHRISTINE [CH]; HU SHOU-IH [US]; DIEFENBACH-STREIBER BEATE [DE]; PRASSLER JOSEF [DE]


Application No.: US20090130124A1  Published: 21/May/2009

Title: Method for altering hematopoietic progenitor cell adhesion, differentiation, and migration

Applicant/Assignee:

Application No.: 10/573944   Filing Date: 28/Sep/2004

Abstract:

The present invention satisfies the need in the art by providing methods for altering hematopoietic progenitor cell adhesion and/or migration to a target tissue, and for altering hematopoietic progenitor cell differentiation into a second cell type. The invention also provides methods for screening test compounds for altering the level of hematopoietic progenitor cell adhesion and/or migration to a target tissue, and for altering hematopoietic progenitor cell differentiation into a second cell type. The invention further provides methods for isolating hematopoietic progenitor cells.

Priority: US20030507202P Applic. Date: 2003-09-29; WO2004US31825 Applic. Date: 2004-09-28

Inventor: VARNER JUDITH A [US]


Application No.: US20090130150A1  Published: 21/May/2009

Title: Biologically Active Nanoparticles A Carbonate-Substituted Hydroxyapatite, Process For Their Preparation And Compositions Incorporating The Same

Applicant/Assignee:

Application No.: 11/916022   Filing Date: 30/May/2006

Abstract:

The invention relates to biologically active nanoparticles of a carbonate-substituted non-stoichiometric hydroxyapatite, having: a) a crystallinity degree CD lower than 40%, the crystallinity degree being defined as CD=(1-X/Y).100 wherein: Y=height of the diffraction maximum at 2theta=33 DEG , X=height of the diffraction background at 2theta=33 DEG of the nanoparticles X-ray diffraction pattern

b) a length L ranging from 20 to 200 nm and a width W ranging from 5 to 30 nm

and c) an aspect ratio AR comprised between 2 and 40, the aspect ratio being defined as AR=L/W. The biologically active nanoparticles of the invention find a preferred use in oral or dental hygiene applications and may be formulated as compositions for oral or dental hygiene such as, for example, solutions, suspensions, oils, gels or other solid products. Other aspects of the invention include a process for preparing a suspension for oral or dental hygiene including the aforementioned biologically active nanoparticles, a process for manufacturing a toothpaste comprising the nanoparticles, as well as a method of locally remineralizing the teeth comprising contacting the teeth with the nanoparticles.

Priority: WO2006EP05146 Applic. Date: 2006-05-30

Inventor: GAZZANIGA GIANCARLO [IT]; ROVERI NORBERTO [IT]; RIMONDINI LIA [IT]; PALAZZO BARBARA [IT]; IAFISCO MICHELE [IT]; GUALANDI PAOLO [IT]


Application No.: US20090130169A1  Published: 21/May/2009

Title: STERILIZING COMPOSITIONS COMPRISING PHOSPHORS FOR CONVERTING ELECTROMAGNETIC RADIATION TO UVC RADIATION AND METHODS FOR USING THE SAME

Applicant/Assignee:

Application No.: 12/269900   Filing Date: 13/Nov/2008

Abstract:

There is disclosed a composition for converting electromagnetic energy to ultraviolet C (UVC) radiation or radiation of a shorter wavelength, the composition comprising at least one phosphor capable of converting an initial electromagnetic energy (A) to an electromagnetic energy (B) comprising UVC radiation or radiation of a shorter wavelength, and an organic or inorganic media containing said phosphor. There is also a method of sterilizing an article by exposing it to UVC radiation or radiation of a shorter wavelength for a time sufficient to deactivate or kill at least one microorganism and/or for a time sufficient to inhibit abnormal cell growth within the body, when said composition is in an implantable medical device. A method of coating an article with such compositions is also disclosed.

Priority: US20070988466P Applic. Date: 2007-11-16

Inventor: BERNSTEIN ERIC F [US]


Application No.: US20090130177A1  Published: 21/May/2009

Title: DENTAL IMPLANT AND PRODUCTION METHOD FOR SAID IMPLANT

Applicant/Assignee: THOMMEN MEDICAL AG

Application No.: 12/091925   Filing Date: 17/Oct/2006

Abstract:

The invention relates to a dental implant, which comprises a coating at least in those surface areas that come into contact with hard and/or soft tissue when implanted. To ensure that the active ingredient contained in the coating (bisphosphonate) is released into the surrounding tissue or can act in the latter in a controlled manner at the correct speed, the coating is characterised in that it contains bisphosphonate, the respective pharmaceutically compatible salts or esters of the latter, in addition to at least one amphiphilic component, selected from the group containing branched or linear, substituted or unsubstituted, saturated or partially unsaturated C10-C30 alkyl-, alkenyl, alkylaryl-, aryl-, cycloalkyl-, alkylcycloalkyl-, alkylcycloaryl-carboxylates, -phosphates or -sulfates or mixtures thereof and/or a water-soluble ionic polymer component. The invention also relates to a method for producing a dental implant of this type and to a specific composition, which can be used to produce a coating of this type.

Priority: CH20050001723 Applic. Date: 2005-10-27; WO2006CH00577 Applic. Date: 2006-10-17

Inventor: SCHLOTTIG FALKO [CH]; SCHNABELRAUCH MATTHIAS [DE]; KAUTZ ARMIN REX [DE]


Application No.: US20090130178A1  Published: 21/May/2009

Title: FORMULATION FOR DECREASING TOBACCO, ALCOHOL, DRUG OR FOOD CONSUMPTION

Applicant/Assignee: XVASIVE, INC

Application No.: 11/942414   Filing Date: 19/Nov/2007

Abstract:

Formulations have been developed which assist individuals having an addiction such as smoking to reduce or quit engaging in the addictive behavior. Representative behaviors include smoking, excessive alcohol or food ingestion, drug addiction, and ingestion of caffeine or junk food providing quick "highs". The formulations assist the smoker to become dissatisfied with smoking, until he or she willingly gives up the habit or at least cuts down on the number of cigarettes smoked per day as an initial step towards quitting in the future. The formulations can also be used in conjunction with other known formulations, such as nicotine gum or patch. The formulations contain hydrophilic polymers, for example, polyethylene glycol (PEG) alone or in combination or polyvinyl pyrrolidone (PVP) (also known as povidone or polyvidone alone or in combination.), sweeteners and/or flavorings, viscosity modifiers/binders, and pH or buffering agents.

Priority:

Inventor: ORONSKY BRYAN T [US]; ORONSKY NEIL C [US]; ORONSKY ARNOLD L [US]


Application No.: US20090130627A1  Published: 21/May/2009

Title: Diamond dust polishing cloth for natural tooth enamel and dental veneers

Applicant/Assignee:

Application No.: 12/288644   Filing Date: 22/Oct/2008

Abstract:

A disposable tooth cleaning article for manually cleaning tooth surfaces is disclosed. The disposable tooth cleaning article extends in a longitudinal direction and a transverse direction, and has a finger faced surface and an outer surface. The disposable tooth cleaning article comprises a single sheet. The outer surface is provided with a diamond dust polishing agent for home use and professional use in the care of natural tooth enamel and dental veneers comprised of a quantity of diamond dust coated with a lubricant in conjunction with a paste for carrying the lubricant coated diamond dust, or other semi-precious, non-toxic abrasive dust, said diamond dust being of a size of approximately 500 nanometers or less to a size of approximately 5 nanometers. The size of the dust of both the diamond and the semi-precious stone may vary, depending on the degree of abrasiveness and the lubricant employed. The diamond dust (and semi-precious dust) polishing agent permits the user to maintain the polish and luster of the natural tooth enamel and veneer at home without adversely abrading or damaging the surface thereof.

Priority: US20070003552P Applic. Date: 2007-11-16

Inventor: HERMAN MICHAEL [US]


Application No.: US20090130637A1  Published: 21/May/2009

Title: Tongue scraper

Applicant/Assignee:

Application No.: 11/985954   Filing Date: 19/Nov/2007

Abstract:

The present invention is a tongue cleaning device that reduces or eliminates the gag reflex during use comprising, a body having a first end and a second end. The first end forming an elongated handle having a contour for ease of handling and use and a gripping means. The second end forming a head having two or more elongated apertures forming at least two parallel ridges perpendicular to the handle. The head being flat and narrow in width and the body being narrow in thickness thereby eliminating or reducing the gag reflex during use.

Priority:

Inventor: PANTANGCO III IRINEO MARVIN [US]


Application No.: US20090130880A1  Published: 21/May/2009

Title: LAMP HOLDER

Applicant/Assignee: BJB GMBH & CO. KG

Application No.: 12/191806   Filing Date: 14/Aug/2008

Abstract:

A bipin fluorescent-lamp holder has a housing formed with an outwardly open housing mouth and a rotor rotatable in the housing adjacent the mouth about an axis and having a diametrally throughgoing rotor slot. The rotor is rotatable between an installation position with the rotor slot aligned with the slot and an angularly offset contact position with the slot not aligned with the mouth. The rotor and housing are so dimensioned as to receive the pins extending parallel to the axis and to move the pins in a circular orbit centered on the axis on rotation of the rotor in the housing, and contacts in the housing diametrally flanking the axis each having a main part lying outside the orbit and a contact part engageable into the orbit. The contacts pins are aligned with the slot and project into ends of the slot and into engagement with the pins only in the contact position of the rotor.

Priority: DE200710054930 Applic. Date: 2007-11-17; DE200710051431 Applic. Date: 2007-10-25

Inventor: VOGT KARL-WILHELM [DE]; GRESCHNER HARTMUT [DE]; NASSE MARKUS [DE]


Application No.: US20090131318A1  Published: 21/May/2009

Title: Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules

Applicant/Assignee:

Application No.: 12/157150   Filing Date: 06/Jun/2008

Abstract:

Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines.

Priority: US2007-656921 Applic. Date: 2007-01-22; US2003-658834 Applic. Date: 2003-09-08; US20030457135P Applic. Date: 2003-03-21; US20020409898P Applic. Date: 2002-09-09

Inventor: GANTIER RENE [FR]; VEGA MANUEL [FR]; DRITTANTI LILA [FR]; GUYON THIERRY [FR]


Application No.: US20090131330A1  Published: 21/May/2009

Title: PAR-2 AGONIST

Applicant/Assignee: KOWA CO., LTD

Application No.: 11/722952   Filing Date: 27/Dec/2005

Abstract:

Disclosed is a compound represented by the following general formula (1): Ar-CO-AA1-AA2-AA3-AA4-NH-X-NR1R2 (1) (wherein Ar represents an optionally substituted phenyl group or an aromatic heterocyclic group

AA1 represents a hydrophobic amino acid

AA2 represents an unsubstituted amino acid containing 2 or more carbon atoms

AA3 represents an unsubstituted amino acid containing 2 or more carbon atoms

AA4 represents a hydrophobic amino acid

X represents a divalent saturated aliphatic hydrocarbon group having 2-6 carbon atoms

and R1 and R2 may be the same or different and independently represent a saturated or unsubstituted aliphatic hydrocarbon group having 1-8 carbon atoms, or alternatively R1 and R2 may form a ring together with an adjacent nitrogen atom), a salt thereof, or a solvate of them. Also disclosed is a pharmaceutical composition for prevention/treatment of diseases associated with PAR-2 which is composed of the compound represented by the above general formula (1), a salt thereof or a solvate of them and a pharmaceutically acceptable carrier.

Priority: US20040639403P Applic. Date: 2004-12-28; WO2005JP23852 Applic. Date: 2005-12-27

Inventor: ISHIWATA HIROYUKI [JP]; KABEYA MOTOTSUGU [JP]; KANKE TORU [JP]


Application No.: US20090131401A1  Published: 21/May/2009

Title: Transcription factor modulating compounds and methods of use thereof

Applicant/Assignee: PARATEK PHARMACEUTICALS, INC

Application No.: 12/069723   Filing Date: 12/Feb/2008

Abstract:

Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms.

Priority: US2003-700661 Applic. Date: 2003-11-03; US2002-139591 Applic. Date: 2002-08-14; US20020423319P Applic. Date: 2002-11-01; US20020425916P Applic. Date: 2002-11-13; US20010288660P Applic. Date: 2001-05-04

Inventor: LEVY STUART B [US]; ALEKSHUN MICHAEL N [US]; PODLOGAR BRENT L [US]; OHEMENG KWASI [GH]; VERMA ATUL K [US]; WARCHOL TADEUSZ [US]; BHATIA BEENA [US]; BOWSER TODD [US]; GRIER MARK [US]


Application No.: US20090131440A1  Published: 21/May/2009

Title: HETEROCYCLIC DERIVATIVES AS MODULATORS OF ION CHANNELS

Applicant/Assignee:

Application No.: 12/269108   Filing Date: 12/Nov/2008

Abstract:

The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Priority: US20070987485P Applic. Date: 2007-11-13; US20080088141P Applic. Date: 2008-08-12

Inventor: STAMOS DEAN [US]; MARTINBOROUGH ESTHER [US]; ZIMMERMANN NICOLE [US]; NEUBERT TIMOTHY [US]; NUMA MEHDI MICHEL DJAMEL [US]; WHITNEY TARA [US]; KAWATKAR AARTI SAMEER [US]


Application No.: US20090131551A1  Published: 21/May/2009

Title: POLYFUNCTIONAL COMPOUNDS AND USES AS IMPLANT MATERIALS

Applicant/Assignee:

Application No.: 12/280929   Filing Date: 27/Feb/2007

Abstract:

The synthesis and characterization of polymer core initiators are described herein. Polymer core initiators are used to prepare the polyfunctional prepolymers described herein, which may be optionally tethered. The polyfunctional prepolymers described herein are used to prepare cements, optionally with added co-monomers, for repairing and restoring tissues.

Priority: US20060777827P Applic. Date: 2006-03-01; WO2007US62882 Applic. Date: 2007-02-27

Inventor: XIE DONG [US]


Application No.: US20090133260A1  Published: 28/May/2009

Title: 3D dental shade matching and apparatus

Applicant/Assignee: IOS TECHNOLOGIES, INC

Application No.: 11/986642   Filing Date: 26/Nov/2007

Abstract:

Systems and methods are disclosed to fabricate a restorative prosthesis. The system includes a scanner to intra orally capture color and translucency information along with a three dimensional (3D) shape of the dentition being reconstructed. The system also includes a computer aided design (CAD) module to receive the color and translucency information and the 3D shape to render a color accurate representation of the prosthesis for review, wherein the color, translucency and surface information is combined in a single digital prescription which is electronically transferred to a laboratory or CAD/CAM system for fabrication. The system provides the capability for 3D shape, color and translucency characteristics of the final prosthesis to be measured and quantitatively compared to the prescribed requirements.

Priority:

Inventor: DURBIN DUANE MILFORD [US]; DURBIN DENNIS ARTHUR [US]; DYMEK MARTY J [US]; WARDEN LAURENCE [US]


Application No.: US20090136432A1  Published: 28/May/2009

Title: Oral Stannous Compositions

Applicant/Assignee:

Application No.: 12/266937   Filing Date: 07/Nov/2008

Abstract:

The present invention relates to an aqueous oral composition comprising: a) from 0.2% to 3% divalent metal ions comprising: i. from 0.1% to 1.5% of zinc ions

ii. from 0.1% to 2% of tin (II) ions

and b) a source of fluoride ions

c) a silica dental abrasive

d) one or more chelants having a MW of less than 1000 and capable of forming water-soluble complexes with the zinc ions, wherein the chelants comprise less than 0.2% linear polyphosphates having a chain length of four or more

e) an orally acceptable carrier comprising at least 20% total water

wherein the pH of the composition is from 5 to 6.5, the molar ratio of the chelants to the divalent metal ions is at least 0.70:1 and at least 80% by weight of the total zinc ions are solubilised within the composition. The composition of the invention has been found to give improved antimicrobial activity from the zinc/stannous combination without significant taste, staining or stability problems, compared to compositions having lower levels of chelants.

Priority: EP20070120425 Applic. Date: 2007-11-09

Inventor: STRAND ROSS [GB]; PRENDERGAST MAURICE JOSEPH [GB]; WANG XIAOLI [CN]


Application No.: US20090136486A1  Published: 28/May/2009

Title: Biomarkers for human papilloma virus-associated cancer

Applicant/Assignee:

Application No.: 12/220465   Filing Date: 24/Jul/2008

Abstract:

Cervical cancer cells and HPV+ head and neck cancer cells express three testis-specific genes not normally expressed in somatic cells: testicular cell adhesion molecule 1 (TCAM1), synaptonemal complex protein 2 (SYCP2) and stromal antigen 3 (STAG3). Among the three markers, TCAM1 and SYCP2 are early detection markers. Various methods for identifying a human or non-human animal as a candidate for further examination for cervical cancer, preneoplastic lesion for cervical cancer, head and neck cancer, or preneoplastic lesion for head and neck cancer are disclosed. Methods of detecting said cancers and preneoplastic lesions, methods of screening for drugs for treating said cancers and preneoplastic lesions, methods for monitoring the effectiveness of a treatment for said cancers, and methods of treating said cancers are also disclosed. Further disclosed are kits that can be used to practice the above methods.

Priority: US20070961774P Applic. Date: 2007-07-24

Inventor: PYEON DOHUN [US]; LAMBERT PAUL F [US]; NEWTON MICHAEL A [US]; AHLQUIST PAUL G [US]


Application No.: US20090136584A1  Published: 28/May/2009

Title: TOOTHPASTE

Applicant/Assignee: KAO CORPORATION

Application No.: 12/359385   Filing Date: 26/Jan/2009

Abstract:

A toothpaste filled in a container which has two chambers and is capable of simultaneously discharging two different compositions filled respectively in the two chambers when the main body of the container is pressed, wherein a ratio of a storage modulus GA' of Composition (A) filled in one chamber to a storage modulus GB' of Composition (B) filled in the other chamber falls within a range of from 0.6 to 1.4. By controlling the ratio, it is possible to stably discharge from the container storing these two compositions separately predetermined amounts of these two compositions which will otherwise cause a time-dependent change if they are pre-mixed thereby failing to attain the purpose of their addition.

Priority: JP20010327367 Applic. Date: 2001-10-25; JP20020065550 Applic. Date: 2002-03-11; US2004-492199 Applic. Date: 2004-04-21; WO2002JP11099 Applic. Date: 2002-10-25

Inventor: HOSOYA MANABU [JP]; OSHINO KAZUSHI [JP]; MATSUMOTO HIROMASA [JP]; KITSUNAI YOSHITAKA [JP]


Application No.: US20090136893A1  Published: 28/May/2009

Title: Oral appliance for delivering a medicament

Applicant/Assignee:

Application No.: 11/986727   Filing Date: 26/Nov/2007

Abstract:

An oral appliance is provided for delivering a medicament to at least a portion of teeth and/or soft tissue areas inside a mouth, the oral appliance comprising an interior surface having a porous material disposed on at least a portion of the interior surface of the oral appliance, the porous material containing a medicament and the interior surface being formed to fit contours of at least the portion of the teeth and/or soft tissue areas inside the mouth and being capable of supporting and holding the porous material in contact with at least the portion of the teeth and/or soft tissue areas inside the mouth to deliver the medicament.

Priority:

Inventor: ZEGARELLI PETER JOHN [US]


Application No.: US20090136896A1  Published: 28/May/2009

Title: DENTAL APPARATUS FOR SHAPING AND CLEANING A ROOT CANAL

Applicant/Assignee: MICRO MEGA INTERNATIONAL MANUFACTURES (SOCIETE ANONYME)

Application No.: 12/160274   Filing Date: 10/Jan/2007

Abstract:

Apparatus is disclosed for use in cleaning dental root canals using an endodontic file. The file is mounted in a drill head driven by an electric motor. The motor is normally driven in one, forward direction, but periodically, the motor rotation is reversed for a very short time. The duration of the motor reversal is so short that although the motor rotates in the reverse direction, the inertia and backlash in the transmission between the motor output shaft and the drill head is such that the direction of rotation of the file in the root canal is not changed.

Priority: GB20060001361 Applic. Date: 2006-01-24; WO2007IB00546 Applic. Date: 2007-01-10

Inventor: MEYER SHUSTER DAVID [GB]


Application No.: US20090136988A1  Published: 28/May/2009

Title: METHOD AND DEVICE TO FRACTIONATE STEM CELLS

Applicant/Assignee:

Application No.: 12/299350   Filing Date: 30/Apr/2007

Abstract:

A method and the relevant instrumentation to fractionate living, adherent stem cells, particularly of human origin, from different sources is disclosed, said method is based on the non-equilibrium, dynamic fractionation of cells assisted by the Earth gravity field.

Priority: IT2006RM00240 Applic. Date: 2006-05-04; IT2006RM00572 Applic. Date: 2006-10-24; WO2007EP54226 Applic. Date: 2007-04-30

Inventor: RESCHIGLIAN PIERLUIGI [IT]; RODA BARBARA [IT]; BAGNARA GIAN PAOLO [IT]; ZATTONI ANDREA [IT]


Application No.: US20090137480A1  Published: 28/May/2009

Title: TRANSDERMAL DELIVERY SYSTEM FOR DRIED PARTICULATE OR LYOPHILIZED MEDICATIONS

Applicant/Assignee:

Application No.: 12/357283   Filing Date: 21/Jan/2009

Abstract:

The present invention provides a system for transdermal delivery of dried or lyophilized pharmaceutical compositions and methods using thereof. The system comprises an apparatus for facilitating transdermal delivery of an agent that generates hydrophilic micro-channels, and a patch comprising a therapeutically active agent. The present invention is useful for transdermal delivery of hydrophilic agents, particularly of high molecular weight proteins.

Priority: IL20020152574 Applic. Date: 2002-10-31; US2006-582920 Applic. Date: 2006-10-17; US2003-699582 Applic. Date: 2003-10-31

Inventor: STERN MEIR [IL]; LEVIN GALIT [IL]


Application No.: US20090137584A1  Published: 28/May/2009

Title: SULFONYL BENZIMIDAZOLE DERIVATIVES

Applicant/Assignee: PFIZER INC

Application No.: 12/280586   Filing Date: 23/Feb/2007

Abstract:

This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein A, R1, R2, R3, R4, R5, m and n are each as described herein, and compositions containing such compounds, and the use of such compounds in the treatment of a condition mediated by CB2 receptor activity such as, but not limited to, inflammatory pain, nociceptive pain, neuropathic pain, fibromyalgia, chronic low back pain, visceral pain, acute cerebral ischemia, pain, chronic pain, acute pain, post herpetic neuralgia, neuropathies, neuralgia, diabetic neuropathy, HIV-related neuropathy, nerve injury, rheumatoid arthritic pain, osteoarthritic pain, back pain, cancer pain, dental pain, fibromyalgia, neuritis, sciatica, inflammation, neurodegenerative disease, cough, broncho constriction, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), colitis,

cerebrovascular ischemia, emesis such as cancer chemotherapy-induced emesis, rheumatoid arthritis, asthma, Crohn's disease, ulcerative colitis, asthma, dermatitis, seasonal allergic rhinitis, GERD, constipation, diarrhea, functional gastrointestinal disorders, irritable bowel syndrome, cutaneous T cell lymphoma, multiple sclerosis, osteoarthritis, psoriasis, systemic lupus erythematosus, diabetes, glaucoma, osteoporosis, glomerulonephritis, renal ischemia, nephritis, hepatitis, cerebral stroke, vasculitis, myocardial infarction, cerebral ischemia, reversible airway obstruction, adult respiratory disease syndrome, COPD, cryptogenic fibrosing alveolitis and bronchitis.

Priority: US20060779776P Applic. Date: 2006-03-06; US20060795354P Applic. Date: 2006-04-26; WO2007IB00474 Applic. Date: 2007-02-23

Inventor: KATO TOMOKI [JP]; KON-I KANA [JP]; YUKI YOHEI [JP]; ANDO KAZUO [JP]


Application No.: US20090137617A1  Published: 28/May/2009

Title: USE OF HAPTOGLOBIN GENOTYPING IN DIAGNOSIS AND TREATMENT OF CARDIOVASCULAR DISEASE

Applicant/Assignee:

Application No.: 12/276963   Filing Date: 24/Nov/2008

Abstract:

This invention is directed to methods and compositions for the treatment of cardiovascular disorders. Specifically, the invention is directed to compositions comprising vitamin E, statins and/or glutathione peroxidase mimetics

methods of treating diabetic patients expressing the Hp-2-2 haptoglobin genotype

a method of inhibiting or suppressing a cardiovascular disorder in a diabetic subject, treating cardiovascular disease in subjects exhibiting the Haptoglobin Hp-2-2 genotype

and methods of treating cardiovascular disease in subjects exhibiting the Haptoglobin Hp-2-2 genotype.

Priority: US20070996552P Applic. Date: 2007-11-23

Inventor: LEVY ANDREW [IL]


Application No.: US20090137625A1  Published: 28/May/2009

Title: Novel Enantiomers and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee:

Application No.: 11/887246   Filing Date: 06/Apr/2006

Abstract:

This invention relates to novel enantiomers useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000505 Applic. Date: 2005-04-08; DK20050001572 Applic. Date: 2005-11-11; US20050669918P Applic. Date: 2005-04-11; US20050736331P Applic. Date: 2005-11-15; WO2006EP61363 Applic. Date: 2006-04-06

Inventor: PETERS DAN [SE]; DAHL BJARNE H [DK]; OLESEN DORTHE FILTENBORG [DK]; NIELSEN ELSEBET OSTERGAARD [DK]; OLSEN GUNNAR M [DK]; REDROBE JOHN PAUL [DK]


Application No.: US20090137697A1  Published: 28/May/2009

Title: Dental Curable Composition and Kit for Such Dental Curable Composition

Applicant/Assignee: SUN MEDICAL CO., LTD

Application No.: 12/063200   Filing Date: 08/Aug/2006

Abstract:

A dental curable composition has a curing time of 30 seconds to 120 minutes and includes a compound having an acidic group in the molecule (A), a polymerizable monomer (B), an organic amine compound (C) and a sulfur-containing reducing compound (D). In the dental curable composition, the content of the component (A) is 0.01 to 80 parts by weight, the content of the component (B) is 21 to 99.8 parts by weight, the content of the component (C) is 0.01 to 30 parts by weight and the content of the component (D) is 0 to 30 parts by weight. The composition may be cured at a relatively low temperature close to the body temperature without using a peroxide-based polymerization initiator, and has good sealing properties and adhesion.

Priority: JP20050229625 Applic. Date: 2005-08-08; WO2006JP315685 Applic. Date: 2006-08-08

Inventor: ORI TATSUYA [JP]; NISHITANI HARUKA [JP]; YAMAMOTO YUYA [JP]; YAMAMOTO TAKASHI [JP]


Application No.: US20090137750A1  Published: 28/May/2009

Title: Process for preparing low-viscosity allophanates containing actinically curable groups

Applicant/Assignee:

Application No.: 12/229185   Filing Date: 20/Aug/2008

Abstract:

The present invention relates to a process for preparing low-viscosity reaction products of polyisocyanates containing activated groups which react, with polymerization, with ethylenically unsaturated compounds on exposure to actinic radiation.

Priority: DE200710040240 Applic. Date: 2007-08-25

Inventor: LUDEWIG MICHAEL [DE]; FISCHER WOLFGANG [DE]; KUCZEWSKI HELMUT [DE]


Application No.: US20090139433A1  Published: 04/Jun/2009

Title: DENTAL MATERIALS BASED ON ALKYLENEDIAMINE-N,N,N',N'- TETRAACETIC ACID- (METH)ACRYLAMIDES

Applicant/Assignee: IVOCLAR VIVADENT AG

Application No.: 12/207622   Filing Date: 10/Sep/2008

Abstract:

The present invention relates to an alkylenediamine-N,N,N',N'-tetraacetic acid-(meth)acrylamide of formula (I) The invention also relates to a polymerizable composition which is characterized in that it comprises at least one alkylenediamine-N,N,N',N'-tetraacetic acid-(meth)acrylamide of formula (I), and its use in particular as dental material.

Priority: EP20070023228 Applic. Date: 2007-11-30

Inventor: MOSZNER NORBERT [LI]; ANGERMANN JORG [CH]; FISCHER URS KARL [CH]; RHEINBERGER VOLKER M [LI]


Application No.: US20090142279A1  Published: 04/Jun/2009

Title: NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS

Applicant/Assignee:

Application No.: 11/719335   Filing Date: 15/Nov/2005

Abstract:

Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.

Priority: US20040627822P Applic. Date: 2004-11-15; WO2005US41230 Applic. Date: 2005-11-15

Inventor: BUDZIK BRIAN W [US]


Application No.: US20090142281A1  Published: 04/Jun/2009

Title: Composition Comprising A Coupled Enzyme System

Applicant/Assignee:

Application No.: 12/106780   Filing Date: 21/Apr/2008

Abstract:

The present invention relates to a composition comprising a coupled enzyme system for the rapid and efficient production of hydrogen peroxide by the coupling of a first enzyme system capable of hydrogen peroxide generation, to a second enzyme system which utilizes the non hydrogen peroxide product of the first enzyme system, and optionally is capable of generating further hydrogen peroxide.

Priority: DK20050001474 Applic. Date: 2005-10-21; WO2006DK00590 Applic. Date: 2006-10-20

Inventor: RAND THOMAS [DK]; MADRID SUSAN MAMPUSTI [DK]


Application No.: US20090142282A1  Published: 04/Jun/2009

Title: High-solids alcoholic solutions of rosin esters for varnish applications

Applicant/Assignee:

Application No.: 12/315208   Filing Date: 01/Dec/2008

Abstract:

High-solids solutions of solid rosin esters and lower alcohols can be obtained at rosin ester concentrations above the binary solubility of the rosin ester in the alcohol. Such solutions can be achieved by adding an additional modified rosin or by dissolving a small amount of the alcohol in the rosin ester. These solutions are useful as varnishes for use on humans and animals, particularly when ethanol is the alcohol. The varnish may optionally contain a therapeutic agent.

Priority: US20070005215P Applic. Date: 2007-12-04

Inventor: KENDALL JONATHAN LEE [US]; KENDALL DONALD WILSON [US]


Application No.: US20090142295A1  Published: 04/Jun/2009

Title: Anti-Connexin Compounds and Uses Thereof

Applicant/Assignee:

Application No.: 11/883739   Filing Date: 03/Feb/2006

Abstract:

Methods and compositions for modulating the activities of connexins are provided, including, for example, for use for treatment of cardiovascular, vascular, neurological, for wounds and for other indications. These compounds and methods can be used therapeutically, for example, to reduce the severity of adverse effects associated diseases and disorders where localized disruption in direct cell-cell communication or prevention of hemichannel opening is desirable.

Priority: US20050650075P Applic. Date: 2005-02-03; WO2006IB01961 Applic. Date: 2006-02-03

Inventor: BECKER DAVID L [GB]


Application No.: US20090142469A1  Published: 04/Jun/2009

Title: PROTEIN-FREE CREAMERS, STABILIZING SYSTEMS, AND PROCESS OF MAKING SAME

Applicant/Assignee:

Application No.: 11/947532   Filing Date: 29/Nov/2007

Abstract:

Protein-free creamer compositions and stabilizing systems contained therein. The creamer composition includes an emulsifying component of at least two low molecular weight emulsifiers in relative amounts sufficient to provide a stabilized emulsion, a cellulose component including a blend of microcrystalline cellulose and carboxymethylcellulose in an amount sufficient to maintain homogeneity of the composition

and a carageenan gum component present in an amount sufficient to maintain homogeneity of the composition. The creamer composition can be in the form of a shelf stable aseptic liquid creamer that is stable for at least about 9 months, an extended-shelf life (ESL) liquid creamer that is stable for at least about four months at refrigeration, or a powder that is stable for at least 24 months at ambient conditions. The creamer composition provides sufficient whitening capacity and a pleasant mouth feel without discernable feathering and without discernable fat separation when added to liquid beverages.

Priority:

Inventor: SHER ALEXANDER A [US]; OCTAVIA WINNIE [US]; PALAG EDSEL N [US]; TUOT JAMES [US]


Application No.: US20090142729A1  Published: 04/Jun/2009

Title: Method and Releasably Connecting a Tool to a Dental Handpiece and Connection Between the Tool and Dental Handpiece

Applicant/Assignee:

Application No.: 11/989782   Filing Date: 29/Jul/2006

Abstract:

The invention relates to a method for establishing a releasable connection between a tool connection or coupling piece, which is formed on a dental handpiece, and the tool shank of a dental hand instrument. In order to connect a journal-like fastening section, which tapers toward a free end, on one of the elements to be connected, is inserted into an opening while matching the same, which is adapted to this section, on the other of the elements to be connected.

Priority: DE200510036466 Applic. Date: 2005-08-03; DE200610026831 Applic. Date: 2006-06-07; DE200610034658 Applic. Date: 2006-07-24; WO2006DE01329 Applic. Date: 2006-07-29

Inventor: NEUMEYER STEFAN [DE]


Application No.: US20090142730A1  Published: 04/Jun/2009

Title: Device for holding a dental instrument

Applicant/Assignee:

Application No.: 11/658302   Filing Date: 12/Apr/2005

Abstract:

The invention relates to a device for holding a dental instrument in the head of a contra-angle, an instrument of the type comprising, in its upper part which is inserted into the head of the contra-angle, a lateral flat for rotating it and an annular groove for axially retaining it, characterized in that the shank receiving the handle of the instrument, comprises a transverse cutback (7d), offset with respect to the longitudinal axis (7e) of the shank, made in the end of the shank and emerging in the bore (7b), the width (1) of the cutback being such that it allows the handle of the instrument to be engaged so that, on the one hand, the lateral flat of the handle is in contact with the wall (7f) of the cutback, closest to the longitudinal axis (7c), so as to ensure rotational coupling, and that, on the other hand, the shoulder of the flat of the handle abuts against the bottom (7c)

of the longitudinal bore (7b) of the shank, in order to act as an axial stop in the direction of insertion. Preferably, the device is in the form of a cartridge comprising, already assembled, a shank (7), a shank bearing (10), a resilient ring (8), a push-button (13) with a spring (12), and optionally a ball bearing (11).

Priority: FR20040008252 Applic. Date: 2004-07-27; WO2005FR00875 Applic. Date: 2005-04-12

Inventor: PERNOT JACQUES [FR]


Application No.: US20090145801A1  Published: 11/Jun/2009

Title: Carry all shower tote

Applicant/Assignee:

Application No.: 12/284576   Filing Date: 23/Sep/2008

Abstract:

The invention is a device for holding, transporting and dispensing toiletries which comprises: a rigid, hinged five part structure comprised of four panels of unique function, some with dispensing (containing or storing) mechanisms, along with a non slip handle, or, holder for hanging the device from a shower head, or, any suitable protruding implement which would allow the non slip holder to fit over it and which would be able to support the invention and the contents of the invention. All panels are joined to one another by moveable hinges, to form, in combination, a device to contain and dispense toiletries, as well as, to hold and store all other sundry toiletries not stored within the dispensing units. The units or panels will be on hinges so that the invention may be folded into a rectangular box for transportation. The folded "box" will be attached while in transportation, or, folded manner, by any of several types of latches to prevent it from opening while in transport.

Priority: US20070975198P Applic. Date: 2007-09-26

Inventor: MOON HELEN JUNE [US]


Application No.: US20090148392A1  Published: 11/Jun/2009

Title: COMPOSITIONS CONTAINING BENEFIT AGENTS PRE-EMULSIFIED USING COLLOIDAL CATIONIC PARTICLES

Applicant/Assignee: AMCOL INTERNATIONAL CORPORATION

Application No.: 12/327570   Filing Date: 03/Dec/2008

Abstract:

A cleansing or a surface-conditioning composition comprising a mixture of (i) and (ii) in water: i) a surfactant selected from the group consisting of anionic, non-ionic, zwitterionic, cationic, and mixtures thereof

and ii) a hydrophobic benefit agent in a particulate form having a mean particle size in the range of 1-1,000 micron, and a specific gravity of >=1, not encapsulated within a film or a capsule-like enclosure, the particulate hydrophobic benefit agent comprising: a) a physically-modified form of the hydrophobic benefit agent

and b) a deposition-aid material bonded to the surface of the physically-modified benefit agent, wherein the bonding between the benefit agent and the deposition-aid material is achieved prior to addition to i), wherein said deposition-aid material is not a surfactant having a weight average molecular weight of less than 5,000 Dalton.

Priority: US2008-152364 Applic. Date: 2008-05-14; US2008-028685 Applic. Date: 2008-02-08; US2006-331248 Applic. Date: 2006-01-12; US20070991806P Applic. Date: 2007-12-03; US20070917832P Applic. Date: 2007-05-14; US20070900250P Applic. Date: 2007-02-08; US20050643430P Applic. Date: 2005-01-12

Inventor: SENGUPTA ASHOKE K [US]


Application No.: US20090148396A1  Published: 11/Jun/2009

Title: BIOCOMPATIBLE BIODEGRADABLE FUMAGILLIN ANALOG CONJUGATES

Applicant/Assignee: MERSANA THERAPEUTICS, INC

Application No.: 12/276856   Filing Date: 24/Nov/2008

Abstract:

Fumagillin analog polymer conjugates, methods of making fumagillin analog polymer conjugates, compositions comprising a polymer conjugate of a fumagillin analog, and methods for treating cancer, or treating angiogenic diseases comprising administering to a subject in need thereof an effective amount of a polymer conjugate of a fumagillin analog, are described. Also described are novel fumagillin analogs, methods of making fumagillin analogs, compositions comprising at least one fumagillin analog, and methods for treating cancer, or treating angiogenic diseases comprising administering to a subject in need thereof an effective amount of a fumagillin analog.

Priority: US20070004582P Applic. Date: 2007-11-28

Inventor: AKULLIAN LAURA C [US]; PETTER RUSSELL C [US]; KANE JOHN J [US]; HAMMOND CHARLES E [US]; YIN MAO [US]; YURKOVETSKIY ALEKSANDR [US]; STEVENSON CHERI A [US]


Application No.: US20090148501A1  Published: 11/Jun/2009

Title: PROCESS FOR THE PREPARATION OF AROMATIZED CHEWING FOAMS FOR COSMETIC PRODUCTS

Applicant/Assignee: BAYER MATERIALSCIENCE AG

Application No.: 12/253559   Filing Date: 17/Oct/2008

Abstract:

The invention relates to a process for the preparation of novel aromatized chewing foams for the oral care sector based on polyurethane-polyureas and aromatizing compositions

Priority: US20070999611P Applic. Date: 2007-10-19

Inventor: HOFACKER STEFFEN [DE]; NIESTEN MEIKE [DE]; RISCHE THORSTEN [DE]; DORR SEBASTIAN [DE]; KRAMER THORSTEN [DE]; SCHWANNECKE DIRK [US]; ROHE GABRIELE [DE]; HEPPERLE JENS [DE]; KEMPKES HARTWIG [DE]; LETMATHE CLAUDIA [DE]


Application No.: US20090148805A1  Published: 11/Jun/2009

Title: PREVISUALIZATION OF DENTAL WORK

Applicant/Assignee:

Application No.: 12/330337   Filing Date: 08/Dec/2008

Abstract:

The invention relates to a dental arch overlay for previsualizing the results of a proposed course of dental treatment in a patient. The dental arch overlay includes a graphic layer with a color image of teeth that graphically simulates the results of a proposed course of dental treatment, an adhesive layer, and a backing layer. The invention also relates to a method of previsualizing the results of a proposed course of dental treatment in a patient.

Priority: US20070992945P Applic. Date: 2007-12-06

Inventor: KOIS JOHN C [US]


Application No.: US20090148812A1  Published: 11/Jun/2009

Title: Device for Dispensing Active or Passive Substance Embedded in the Oral Cavity

Applicant/Assignee:

Application No.: 12/065737   Filing Date: 25/Oct/2006

Abstract:

The present invention relates to a device for retaining and dispensing substances embedded in the oral cavity, More particularly, said device includes at least one or more containers (reservoirs) which container stores the substance

should only one container be present at least one stopper is also present

and a cord which connects the above components and may function also as an anchorage.

Priority: IL20050171649 Applic. Date: 2005-10-27; WO2006IL01227 Applic. Date: 2006-10-25

Inventor: PINES ERELLA [IL]


Application No.: US20090148814A1  Published: 11/Jun/2009

Title: Dentition modeling

Applicant/Assignee:

Application No.: 12/001248   Filing Date: 10/Dec/2007

Abstract:

A dentition model material is comprised of a gypsum composition and an additive, wherein, in response to being scanned, a dentition model produced from the dentition model material is configured to produce a signature associated with the additive.

Priority:

Inventor: LI CHUNHUA [US]; WU KEN [US]; HO PHILIP [US]; KUO ERIC [US]


Application No.: US20090148815A1  Published: 11/Jun/2009

Title: Method and apparatus for tooth whitening

Applicant/Assignee:

Application No.: 12/379051   Filing Date: 11/Feb/2009

Abstract:

Preconditioning mouth rinse, which pre-treats the teeth to better receive a whitening formula containing a photosensitive compound, and a hand-held consumer light source for tooth whitening, which provides rapid tooth whitening, are disclosed. The light source may use a specific range of visible light and also emit heat sufficient to raise the temperature of the teeth a desired amount at a depth up to about 2 mm in the range of about from 1-5 DEG Celsius over a predetermined period of time. The specified wavelengths of the hand-held consumer operable light will activate the photosensitive substance in the whitening formula. The oxidizing compounds may be transparent to light enabling light energy to activate the oxidizing compounds directly on the tooth surface, or to activate a photosensitizing or photosensitive compound added to produce the desired temperature increase.

Priority: US2005-293497 Applic. Date: 2005-12-05; WO2004US10953 Applic. Date: 2004-04-20; WO2003US17631 Applic. Date: 2003-06-05

Inventor: PHILP JR GRAHAM K [US]; BROWN DAMON J [US]; DIASTI TIM [US]


Application No.: US20090149363A1  Published: 11/Jun/2009

Title: COMPOSITIONS INCLUDING HARDNESS IONS AND GLUCONATE AND METHODS EMPLOYING THEM TO REDUCE CORROSION AND ETCH

Applicant/Assignee: ECOLAB INC

Application No.: 12/263021   Filing Date: 31/Oct/2008

Abstract:

The present invention relates to compositions including a water soluble magnesium salt, water soluble calcium salt, and gluconate, which have a beneficial effect on corrosion during cleaning. The present compositions can reduce corrosion of a variety of surfaces including glass, aluminum, chrome, copper, and steel. The present invention also relates to methods employing these compositions.

Priority: US2008-114329 Applic. Date: 2008-05-02; US20070927575P Applic. Date: 2007-05-04

Inventor: SMITH KIM R [US]; LAWRENCE MICHEL M [US]; BARTELME MICHAEL J [US]


Application No.: US20090149405A1  Published: 11/Jun/2009

Title: Virus-like particle containing a Dengue virus recombinant replicon

Applicant/Assignee: TENGEN BIOMEDICAL CO

Application No.: 12/129908   Filing Date: 30/May/2008

Abstract:

The present invention relates virus-like particle vaccine containing dengue virus recombinant replicon as its core and its preparation method. Such vaccine can efficiently express antigen in the infected tells. Because dengue virus can infect dendritic cells, it can efficiently present antigen and has immunity effects. Further, different dengue virus types can be used to repeatedly produce efficient immune response, which strengthen body's immune response against the pathogen containing such antigen. Such vaccine can prevent and cure cancer and viral diseases.

Priority: CN20031015272 Applic. Date: 2003-01-30; CN20031015273 Applic. Date: 2003-01-30; WO2004CN00088 Applic. Date: 2004-01-30; US2005-192923 Applic. Date: 2005-07-29

Inventor: PANG XIAOWU [US]


Application No.: US20090149447A1  Published: 11/Jun/2009

Title: Novel M3 Muscarinic Acetylcholine Receptor Antagonists

Applicant/Assignee: GLAXO GROUP LIMITED

Application No.: 11/719336   Filing Date: 15/Nov/2005

Abstract:

Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.

Priority: US20040627986P Applic. Date: 2004-11-15; WO2005US41346 Applic. Date: 2005-11-15

Inventor: BUDZIK BRIAN W [US]; COOPER ANTHONY W J [GB]; JIN JIAN [US]; LAINE DRAMANE I [US]; MCCLELAND BRENT W [US]; PALOVICH MICHAEL R [US]; RIVERO RALPH A [US]; WANG YONGHUI [US]; XIE HAIBO [US]; ZHU CHONGJIE [US]


Application No.: US20090149673A1  Published: 11/Jun/2009

Title: SYNTHETIC NON-FOULING AMINO ACIDS

Applicant/Assignee: SEMPRUS BIOSCIENCES CORP

Application No.: 12/329360   Filing Date: 05/Dec/2008

Abstract:

Synthetic amino acids containing one or more non-fouling groups or moieties are described herein. In one embodiment, the amino acid has the following chemical formula: where L is a linker group and Z is a non-fouling group including, but not limited to, polyethylene glycol (PEG)

oligoethylene glycol (OEG)

zwitterionic group, such as phosphorycholine, carboxybetaine, and sulfobetaine

groups that are hydrogen bond acceptors but not hydrogen bond donors. The non-fouling amino acids can be incorporated into a bioactive peptide as single amino acid residues, multiples amino acid residues, or as blocks of amino acids. The non-fouling amino acids, or peptides containing one or more non-fouling amino acids, can be applied to surfaces in order to improve biocompatibility, reduce thrombogenesis, and/or reduce fouling by proteins or bacteria present in solution.

Priority: US20080026340P Applic. Date: 2008-02-05; US20070992629P Applic. Date: 2007-12-05

Inventor: ZHANG ZHENG [US]; O'SHAUGHNESSEY WILLIAM SHANNAN [US]; HENCKE MICHAEL [US]; SQUIER TREVOR [US]; LOOSE CHRISTOPHER R [US]


Application No.: US20090149849A1  Published: 11/Jun/2009

Title: Device and method to treat tissue with electtric current

Applicant/Assignee:

Application No.: 12/286126   Filing Date: 26/Sep/2008

Abstract:

A method of modifying properties of intrinsic tissue of an organ is provided. The method includes providing an organ, where a first electrode is disposed proximal to the organ first end. The first electrode has a surface area and insulator. A second electrode is disposed opposite the first electrode, where the organ is disposed between the first electrode and the second electrode. The second electrode has surface area and surface insulator. An organ-shaping device is provided that is disposed on the organ between the electrodes, where the organ-shaping device deforms the organ middle section along at least one lateral direction between the electrodes. An electric current is provided between the first second electrodes, where a current density gradient is provided by the electrode surface areas and the deformed organ middle section, and the properties of the intrinsic muscle tissue are modified according to the current density gradient.

Priority: US20070995532P Applic. Date: 2007-09-26

Inventor: LIN BRYANT [US]; TARIN TATUM [US]; VENOOK ROSS D [US]; HWANG PETER [US]; GOODE RICHARD [US]


Application No.: US20090149947A1  Published: 11/Jun/2009

Title: Implantable device for drug delivery and improved visibility

Applicant/Assignee: J.A.C.C. GMBH

Application No.: 11/628929   Filing Date: 09/Jun/2005

Abstract:

The present invention provides an implantable device as delivery device for at least one therapeutic agent being composed of at least one type of base material comprising at least two types of reservoirs for at least one therapeutic agent whereby each type of reservoir independently provides identical or different release rates for the at least one therapeutic agent.

Priority: EP20040013671 Applic. Date: 2004-06-09; WO2005EP06223 Applic. Date: 2005-06-09

Inventor: FROHWITTER BERNHARD [DE]


Application No.: US20090151098A1  Published: 18/Jun/2009

Title: Cleaning Apparatus for Dental Flossing

Applicant/Assignee:

Application No.: 11/958529   Filing Date: 18/Dec/2007

Abstract:

A cleaning apparatus capable of being used in dental procedures is disclosed. The cleaning apparatus comprises an elongated handle and a cleaning member. The elongated handle comprises a first end portion and a second end portion. The cleaning member comprises a stretchable member and a brush. The stretchable member has a proximal end portion and a distal end portion. The proximal end of the stretchable member is removably coupled to a connecting point between the first end portion of the elongated handle and the second end portion of the elongated handle. The distal end portion of the stretchable member is slidably engaged to the second end portion of the elongated handle. The brush is attached to the distal end portion of the stretchable member.

Priority:

Inventor: WRIGHT DEBBIE [US]


Application No.: US20090151746A1  Published: 18/Jun/2009

Title: Cleaning apparatus for dental flossing

Applicant/Assignee:

Application No.: 12/152871   Filing Date: 19/May/2008

Abstract:

A cleaning apparatus capable of being used in dental procedures is disclosed. The cleaning apparatus comprises an elongated handle and a cleaning member. The elongated handle comprises a first end portion and second end portion with spring tension attached to handle. The detachable dental floss has a proximal end and distil end. The proximal end of dental floss is attached to spring tension and the destil end of the dental floss with the brush is engaged to the pistil end of handle in a way that allows the dental floss to move freely with the spring tension.

Priority: US2007-958529 Applic. Date: 2007-12-18

Inventor: WRIGHT DEBORAH DEBBIE [US]; WRIGHT DAVID ALLEN [US]


Application No.: US20090152330A1  Published: 18/Jun/2009

Title: Dental material for attaching a cast metal structure to a metal coping in the preparation or repair of a dental restoration

Applicant/Assignee:

Application No.: 12/316546   Filing Date: 15/Dec/2008

Abstract:

A dental material composition for attaching a metal structure to a dental coping in the preparation or repair of a dental restoration which includes a component of high-fusing temperature metal particles in a range of between 1-10 weight percent, a component of low fusing temperature metal particles having a melting temperature below the melting temperature of the high-fusing particles in excess of at least 90 weight percent and preferably above about 95 weight percent of the total composition with the low fusing temperature metal particles composed primarily of gold, a small measure of borate fluxes in a range of between 0.1 to 2.0% by weight of the total composition and a volatile binder.

Priority: US2005-243270 Applic. Date: 2005-10-04

Inventor: SHOHER ITZHAK [IL]; WHITEMAN AHARON [IL]


Application No.: US20090155188A1  Published: 18/Jun/2009

Title: MOUTH ENVIRONMENT WITH ORAL COMPOSITION

Applicant/Assignee:

Application No.: 12/248295   Filing Date: 09/Oct/2008

Abstract:

A solid oral composition for providing a mouthwash efficacious effect comprising a non-hygroscopic base, carbamide peroxide, a bacterial immobilizing and sulfur sequestration agent, and an optional antioxidant enzyme.

Priority: US20070978752P Applic. Date: 2007-10-09

Inventor: AUSTIN F RICHARD [US]; AUSTIN BLAINE D [US]


Application No.: US20090155192A1  Published: 18/Jun/2009

Title: Antibacterial 5,5'-disubstituted 3,3' dialkoxy-2,2'-dihydroxy-1,1'-biphenyl

Applicant/Assignee: COLGATE-PAMOLIVE

Application No.: 12/390862   Filing Date: 23/Feb/2009

Abstract:

The invention provides an antiplaque oral composition that includes an orally acceptable carrier

and an antibacterially effective amount of a compound of structure (I) In the structure, R1 and R2 are independently selected from a lower C1-4 alkyl group and R3 and R4 are independently an alkenyl or alkyl group having from 1 to 20 carbon atoms. Also included in the invention are toothpastes or tooth gels that include at least one humectant: at least one abrasive compound

and an antibacterially effective amount of the compound represented by the structure of formula (I). Also provided are methods of inhibiting bacterial growth in the oral cavity of an animal by application of the compound of formula (I).

Priority: US2006-374834 Applic. Date: 2006-03-14; US20050662992P Applic. Date: 2005-03-18

Inventor: SUBRAMANYAM RAVI [US]


Application No.: US20090155317A1  Published: 18/Jun/2009

Title: COSMETIC OR DEMOPHARMACEUTICAL COMPOSITION COMPRISING ENKEPHALIN-DERIVED PEPTIDES TO REDUCE AND/OR ELIMINATE FACIAL WRINKLES

Applicant/Assignee: LIPOTEC, S.A

Application No.: 11/910719   Filing Date: 29/Mar/2006

Abstract:

The invention relates to a cosmetic or dermopharmaceutical composition comprising enkephalin-derived peptides for reducing and/or eliminating facial wrinkles. Said cosmetic or dermopharmaceutical composition for application in the skin, preferably in the skin of the face, to reduce and/or eliminate facial wrinkles, preferably facial expression wrinkles and comprises a cosmetically or dermopharmaceutically effective amount of a peptide of general formula (I). The invention also relates to the use of the peptide of general formula (I) in the preparation of a cosmetic or dermopharmaceutical composition reducing and/or eliminating facial wrinkles.

Priority: ES20050000824 Applic. Date: 2005-04-08; WO2006ES00151 Applic. Date: 2006-03-29

Inventor: FERRER MONTIEL ANTONIO [ES]; CEBRIAN PUCHE JUAN [ES]; PUIG MONTIEL ARTURO [ES]


Application No.: US20090155318A1  Published: 18/Jun/2009

Title: PROCESS TO FORM NANO-SIZED MATERIALS, THE COMPOSITIONS AND USES THEREOF

Applicant/Assignee:

Application No.: 11/933397   Filing Date: 31/Oct/2007

Abstract:

Various embodiments of the invention include systems and methods of generating nano-sized salt particles. These methods include generation of a supersaturated solution of a salt MX by mixing of salts MY and NX in which the solubility of MX is lower than that of MY, NX or NY. In some embodiments, nano-sized particles of MX are grown further by further adiabatic addition of salts MY and/or NX. In some embodiments, MX includes potassium nitrate. Some embodiments include compositions of MX configured for use in treatment of dentine sensitivity.

Priority: US20060855892P Applic. Date: 2006-10-31

Inventor: LEE HOWARD W H [US]


Application No.: US20090155320A1  Published: 18/Jun/2009

Title: Method for producing hydroxyapatite particles

Applicant/Assignee: LISOPHARM AG

Application No.: 11/996254   Filing Date: 21/Jul/2005

Abstract:

This invention relates generally to a preparation of bone repair compositions, and more special refers to a novel technology in preparing a matrix building polymer i.e. collagen with inclusions of hydroxyapatite particles as biomaterial for medical applications. In this composition that consists of hydroxyapatite particles embedded in a matrix at least 50% nm. Said composition is suitable as bone implant material, dental cement and for applications in wound healing.

Priority: WO2005EP07951 Applic. Date: 2005-07-21

Inventor: RUDIN VSEVOLOD NIKOLAEVICH [RU]; MELIKHOV IGOR VITALLEVICH [RU]; MINAEV VLADIMIR VASILLEVICH [RU]; ORLOV ANDREI YURIEVICH [RU]; BOZHEVOLNOV VIKTOR EVGENIEVICH [RU]


Application No.: US20090155622A1  Published: 18/Jun/2009

Title: Titanium-Nickel Alloy, Method for Modifying Titanium-Nickel Alloy Surface, Biocompatible Material

Applicant/Assignee:

Application No.: 11/990172   Filing Date: 08/Aug/2006

Abstract:

Provided is a titanium-nickel alloy improved in corrosion resistance due to the reduced Ni content in the surface layer. Since a film (modified layer) extremely reduced in Ni concentration compared to the interior can be formed on the surface of a titanium-nickel alloy, by applying electrolysis treatment in a properly controlled electrolytic solution, the corrosion resistance of the alloy is improved. Specific examples of the electrolytic solution may include a mixture of glycerol, lactic acid and water (H2O).

Priority: JP20050232502 Applic. Date: 2005-08-10; JP20060098016 Applic. Date: 2006-03-31; WO2006JP315616 Applic. Date: 2006-08-08

Inventor: YONEYAMA TAKAYUKI [JP]; FUKUSHIMA OSAMU [JP]; HANAWA TAKAO [JP]; DOI HISASHI [JP]


Application No.: US20090155740A1  Published: 18/Jun/2009

Title: Ultrasonic Dental Treatment System

Applicant/Assignee: CAO GROUP, INC

Application No.: 12/198234   Filing Date: 26/Aug/2008

Abstract:

The present invention is a personal ultrasonic dental hygiene device. A handle with an ultrasonic transducer is provided with differing dental hygiene attachments for personal use. The device may be powered through a battery or through direct wall socket communication. A variety of controls may be provided to adjust ultrasonic frequency and treatment time.

Priority: US2007-961557 Applic. Date: 2007-12-20; US2004-913702 Applic. Date: 2004-08-06; US20080060806P Applic. Date: 2008-06-11

Inventor: JENSEN STEVEN D [US]; CAO DENSEN [US]


Application No.: US20090156483A1  Published: 18/Jun/2009

Title: Analogs of Ghrelin

Applicant/Assignee:

Application No.: 12/079885   Filing Date: 28/Mar/2008

Abstract:

The invention comprises peptidyl analogs according to formulae (I) or (II) as depicted below: (R2R3)-A1-A2-A3-A4-A5-A6-A7-A8-A9-A10-A11-A12-A13- A14-A15-A16-A17-A18-A19-A20-A21-A22-A23-A24-A25- A-26-A27-A28-R1
wherein the definitions of A1 to A28 and R1 to R3 are provided for in the specification for each of formulae (I) and (II), pharmaceutically acceptable salts thereof and pharmaceutical compositions comprising an effective amount of a compound of formula (I), that possess agonist or antagonist ghrelin activity, along with therapeutic and non-therapeutic uses thereof.

Priority: WO2006US37889 Applic. Date: 2006-09-27; US20050750771P Applic. Date: 2005-12-15; US20050748904P Applic. Date: 2005-12-09; US20050721557P Applic. Date: 2005-09-28

Inventor: DONG ZHENG XIN [US]; CULLER MICHAEL DEWITT [US]; SHEN YEELANA [US]; COMSTOCK JEANNE MARY [US]


Application No.: US20090156563A1  Published: 18/Jun/2009

Title: Glucan Compositions

Applicant/Assignee:

Application No.: 12/085271   Filing Date: 20/Nov/2006

Abstract:

A cosmetic or pharmaceutical composition is provided comprising: a) 0.001 to less than 0.2% by weight, based on the weight of the total composition, of a scleroglucan having a mean molecular weight of 1x106 to 12x106

b) a cosmetically or pharmaceutically acceptable carrier

and, optionally, c) lactic acid, a lactate and/or pentanediol. The composition shows advantageous effects, such as moisturization of skin or mucosa, and has an antiaging and revitalizing effect on the skin. When combined with a certain bactericide as explained in claim 1, compositions containing native polysaccharides of the glucan class in general, especially of the scleroglucan as of component a), are well suitable to reduce the number of bacteria in mucosal or oral environments and minimise adhesion, while retaining a pleasant feeling on the mucosa or gingiva. Plaque thus can be efficiently prevented or removed.

Priority: EP20050111504 Applic. Date: 2005-11-30; EP20060116766 Applic. Date: 2006-07-07; WO2006EP68645 Applic. Date: 2006-11-20

Inventor: BASCHONG WERNER [CH]; MONGIAT SEBASTIEN [FR]; OCHS DIETMAR [DE]


Application No.: US20090156656A1  Published: 18/Jun/2009

Title: USE OF LIGHT-ACTIVE INDOCYANINE GREEN FOR TREATING INFLAMMATORY DISORDERS IN THE ORAL CAVITY

Applicant/Assignee: ELEXXION GMBH

Application No.: 12/281995   Filing Date: 05/Mar/2007

Abstract:

In a process for treating disorders, especially inflammatory disorders, in the oral cavity, by introducing a substance activable by a light source, the substance comprises the active ingredient indocyanine green and the spectrum of the light source emits significant proportions in the range of 700-1000 nm.

Priority: DE200610011043 Applic. Date: 2006-03-08; WO2007EP01867 Applic. Date: 2007-03-05

Inventor: SCHAFER OLAF [DE]; KREJCI DANIELA [CH]; KLARENAAR MARTIN WERNER [DE]


Application No.: US20090157568A1  Published: 18/Jun/2009

Title: Flatware marketing method

Applicant/Assignee:

Application No.: 11/527346   Filing Date: 25/Sep/2006

Abstract:

A method for advertising an eating utensil by using or describing a flavorless taste characteristic of the utensil. Related advertising embodiments are provided.

Priority:

Inventor: LADANYI DONALD J [US]


Application No.: US20090158771A1  Published: 25/Jun/2009

Title: Heat Transfer compositions

Applicant/Assignee: INEOS FLUOR HOLDINGS LIMITED

Application No.: 12/287880   Filing Date: 14/Oct/2008

Abstract:

Heat transfer compositions are usable in their own right or are suitable as a replacement for existing refrigeration usages. The compositions possess a reduced Greenhouse Warming Potential, yet have a capacity and energy efficiency (which may be conveniently expressed as the "Coefficient of Performance") ideally within 20% of the values of those attained using R-134a, and preferably within 10% or less (e.g. about 5%) of these values.

Priority: GB20070019989 Applic. Date: 2007-10-12; GB20080014060 Applic. Date: 2008-08-01

Inventor: LOW ROBERT E [US]; CORR STUART [US]


Application No.: US20090159552A1  Published: 25/Jun/2009

Title: Closure with Hinged Lid for Bottles and the Like with an Automatic Lid Opening System

Applicant/Assignee: SEAPLAST S.A

Application No.: 12/227062   Filing Date: 15/May/2007

Abstract:

Closure with hinged lid for bottles and the like with an automatic lid opening system. The closure includes an elastic element made from elastomer material that exerts a spring-back force on the lid towards its open position, and an anchoring member between the main body of the closure and the lid. The elastic element has an extendible section defined between a first joining area to a main body and a second joining area to the lid. The main body includes a projection that defines a seating surface positioned externally with respect to a hinge joint of the lid. The extendible section extends freely opposite the seating surface and rests on the seating surface in the hinged position of the lid.

Priority: ES20060001273 Applic. Date: 2006-05-18; WO2007EP04306 Applic. Date: 2007-05-15

Inventor: CANO-PEY MAX [ES]; FORT-PRADES JOSEP [ES]


Application No.: US20090162150A1  Published: 25/Jun/2009

Title: DEVICE, AND METHOD FOR FEEDING SUBSTANCES

Applicant/Assignee: FYDEC HOLDING SA

Application No.: 12/392834   Filing Date: 25/Feb/2009

Abstract:

An apparatus for pumping free-flowing materials, having a receptacle coupled to a vacuum pipe and a pumping gas pipe, at least one filter, at least one supply pipe, and at least one drainage pipe for a material being associated with the receptacle. The apparatus includes a vertically extending cylindrical pump chamber configured to pneumatically pump liquids, powder, suspensions and pastes. Further, a device is mounted in an upper region of the pump chamber configured to separate liquid and powder. The device further includes a filter element and a float member. The float member is configured as a sealing element above, and a lower region of the pump chamber is coupled to the at least one supply pipe and the at least one drainage pipe for at least one of a liquid, a powder, a suspension, and a paste.

Priority: DE200610005190 Applic. Date: 2006-02-02; DE200610007277 Applic. Date: 2006-02-15; US2008-278271 Applic. Date: 2008-12-10; WO2007EP00782 Applic. Date: 2007-01-30

Inventor: DIETRICH FREDERIC JUN [CH]


Application No.: US20090162301A1  Published: 25/Jun/2009

Title: Antiseptic Compositions

Applicant/Assignee:

Application No.: 11/916972   Filing Date: 09/Jun/2006

Abstract:

The present invention provides antiseptic compositions that contain DMSO or DMA, an alcohol (e.g., isopropanol), and/or an additional antiseptic agent such as iodine. In certain embodiments, the antiseptic compositions may be used for skin disinfection and/or skin antisepsis (e.g., as applied via a swab).

Priority: US20050689634P Applic. Date: 2005-06-10; WO2006US22752 Applic. Date: 2006-06-09

Inventor: TARRAND JEFFREY J [US]


Application No.: US20090162326A1  Published: 25/Jun/2009

Title: METHOD FOR ISOLATING STEM CELLS AND STEM CELLS DERIVED FROM A PAD-LIKE TISSUE OF TEETH

Applicant/Assignee:

Application No.: 11/997245   Filing Date: 17/Jul/2006

Abstract:

The invention relates to a method for isolating non-embryonic stem cells from a tissue that is located in immediate vicinity of immature, developing teeth or wisdom teeth. The invention further relates to non-embryonic stem cells derived from said tissue. The method according to the invention utilises a living soft tissue residing underneath the dental papilla 12 in immediate vicinity of the apical side of a developing tooth, which is clearly distinguished from other tooth tissue, such as dental papilla 12 or follicle. The pad-like tissue 16 can only be detected in a defined, specific developmental stage in an early phase of root formation. That is, identifying and separating the pad-like tissue 16 is only possible from the appearance of the bony alveolar fundus to the end of the formation of the root of the tooth.

Priority: EP20050016549 Applic. Date: 2005-07-29; WO2006EP06994 Applic. Date: 2006-07-17

Inventor: SIEMONSMEIER JURGEN [DE]; THIE MICHAEL [DE]; DEGISTIRICI OZER [DE]; GOTZ WERNER [DE]


Application No.: US20090162366A1  Published: 25/Jun/2009

Title: HUMAN MONOCLONAL ANTIBODIES TO INFLUENZA M2 PROTEIN AND METHODS OF MAKING AND USING SAME

Applicant/Assignee: KIRIN PHARMA KABUSHIKI KAISHA

Application No.: 12/039632   Filing Date: 28/Feb/2008

Abstract:

Human, humanized and chimeric monoclonal antibodies that bind to influenza M2 protein. The antibodies are useful for, among other things, treatment, diagnostics, purifying and isolating M2 or influenza virus, and identifying the presence of M2 or influenza virus in a sample or a subject.

Priority: WO2003US08147 Applic. Date: 2003-03-13; US2004-909851 Applic. Date: 2004-08-02; US2003-389221 Applic. Date: 2003-03-13; US20020364997P Applic. Date: 2002-03-13

Inventor: MIKAYAMA TOSHIFUMI [JP]; WANG RONGFANG [CN]; KATO SHINICHIRO [JP]


Application No.: US20090162408A1  Published: 25/Jun/2009

Title: COMPOSITIONS CONTAINING CATIONICALLY SURFACE-MODIFIED MICROPARTICULATE CARRIER FOR BENEFIT AGENTS

Applicant/Assignee: AMCOL INTERNATIONAL CORPORATION

Application No.: 12/397043   Filing Date: 03/Mar/2009

Abstract:

A coated microparticulate composition comprising a microparticulate

wherein the microparticulate comprises a benefit agent

and wherein the microparticulate is coated with: a Type-1 Polymer, wherein the Type-1 Polymer comprises a cationic polymer with a cationic atom content greater than about 3 wt. % and a weight average molecular weight less than about 800,000 Dalton

and a Type-2 Polymer, wherein the Type-2 Polymer comprises a cationic polymer with a cationic atom content less than about 3 wt. % and a weight average molecular weight greater than about 1,000,000 Dalton.

Priority: US2008-028685 Applic. Date: 2008-02-08; US2006-331248 Applic. Date: 2006-01-12; US20050643430P Applic. Date: 2005-01-12

Inventor: SENGUPTA ASHOKE K [US]


Application No.: US20090162492A1  Published: 25/Jun/2009

Title: CONSUMABLE CANDY DRINKING STRAW AND A METHOD OF USING THE SAME

Applicant/Assignee:

Application No.: 11/959661   Filing Date: 19/Dec/2007

Abstract:

A drinking straw including an elongated hollow consumable candy shell made from glassified sugar, said candy shell having a cylindrical shape through which liquid is transportable by applying a suction pressure to an end of the candy shell is disclosed herein.

Priority:

Inventor: CONWAY JR W FREDERICK [US]


Application No.: US20090162810A1  Published: 25/Jun/2009

Title: Ultrasonic dental insert and lighted handpiece assembly

Applicant/Assignee:

Application No.: 12/004888   Filing Date: 21/Dec/2007

Abstract:

An ultrasonic dental handpiece and insert assembly is provided. Scaler inserts that can be used to clean and polish tooth surfaces are particularly preferred. A sleeve is removably mounted on the handpiece. The handpiece contains a primary coil and the sleeve encloses a secondary coil, which are inductively coupled together so that electromagnetic energy can be transferred between them. A flexible light guide member having a light source such as a light-emitting diode extends from the sleeve. The light guide can bend and flex in any direction allowing the light source to emit light in any direction.

Priority:

Inventor: WERNER PETER [US]; CHRONISTER BENJAMIN [US]; BARTO MATT [US]


Application No.: US20090163499A1  Published: 25/Jun/2009

Title: Imidazole-substituted arylamides as P2X3 and P2X2/3 antagonists

Applicant/Assignee: ROCHE PALO ALTO LLC

Application No.: 12/316942   Filing Date: 17/Dec/2008

Abstract:

Compounds of the formula I: wherein R1 is optionally substituted imidazolyl, and R2, R3, R4, R5, R6, R7 and R8 are as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist and methods of making the subject compounds.

Priority: US20070007966P Applic. Date: 2007-12-17

Inventor: CHEN LI [CN]; DILLON MICHAEL PATRICK [US]; FENG LICHUN [CN]; HAWLEY RONALD CHARLES [US]; YANG MINMIN [CN]


Application No.: US20090163502A1  Published: 25/Jun/2009

Title: Tetrazole-substituted arylamides as P2X3 and P2X2/3 antagonists

Applicant/Assignee: ROCHE PALO ALTO LLC

Application No.: 12/317026   Filing Date: 17/Dec/2008

Abstract:

Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted tetrazolyl, R2 is optionally substituted phenyl, optionally substituted pyridinyl or optionally substituted thienyl, and R3, R4, R5, R6 R7 and R8 are as defined herein. Also provided are methods of using the compounds for treating diseases associated with the P2X3 and/or a P2X2/3 receptor antagonist and methods of making the compounds.

Priority: US20070007891P Applic. Date: 2007-12-17

Inventor: CHEN LI [CN]; DILLON MICHAEL PATRICK [US]; FENG LICHUN [CN]; HAWLEY RONALD CHARLES [US]; YANG MINMIN [CN]


Application No.: US20090163506A1  Published: 25/Jun/2009

Title: Urea-compounds active as vanilloid receptor antagonists for the treatment of pain

Applicant/Assignee: SMITHKLINE BEECHAM PLC

Application No.: 10/489277   Filing Date: 13/Sep/2002

Abstract:

Certain compounds of formula (I), or a pharmaceutically acceptable salt thereof, or a solvate thereof, wherein R1, R2, P, P', n, p, q, r and s are as defined in the specification, a process for preparing such compounds, a pharmaceutical composition comprising such compounds and the use of such compounds and composition in medicine.

Priority: GB20010022156 Applic. Date: 2001-09-13; GB20010030503 Applic. Date: 2001-12-20; GB20010030505 Applic. Date: 2001-12-20; GB20010030547 Applic. Date: 2001-12-20; WO2002GB04206 Applic. Date: 2002-09-13

Inventor: RAMI HARSHAD KANTILAL [GB]; THOMPSON MERVYN [GB]; WYMAN PAUL ADRIAN [GB]


Application No.: US20090163530A1  Published: 25/Jun/2009

Title: FAST DISSOLVING ORALLY CONSUMABLE FILMS

Applicant/Assignee:

Application No.: 12/132276   Filing Date: 03/Jun/2008

Abstract:

Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, methyl salicylate, eucalyptol and menthol. The edible films are effective at killing the plaque-producing germs that cause dental plaque, gingivitis and bad breath. The film can also contain pharmaceutically active agents. Methods for producing the films are also disclosed.

Priority: US2003-684778 Applic. Date: 2003-10-14; US2002-081018 Applic. Date: 2002-02-21; US1999-395104 Applic. Date: 1999-09-14; US19980101798P Applic. Date: 1998-09-25

Inventor: LEUNG SAU-HUNG SPENCE [US]; LEONE ROBERT S [US]; KUMAR LORI D [US]; KULKARNI NEEMA [US]; SORG ALBERT F [US]


Application No.: US20090163551A1  Published: 25/Jun/2009

Title: Compositions and Methods for Treating Diseases

Applicant/Assignee: NOVARTIS AG

Application No.: 12/308163   Filing Date: 13/Jun/2007

Abstract:

This invention relates to methods for treating, preventing and/or managing gastric injury, e.g., NSAID-induced gastric injury in a subject including administering to the subject tegaserod, alone or in combination with a proton pump inhibitor. Also provided are compositions and kits for use in methods of the invention.

Priority: US20060813852P Applic. Date: 2006-06-15; WO2007US71080 Applic. Date: 2007-06-13

Inventor: EARNEST DAVID LEWIS [US]


Application No.: US20090166437A1  Published: 02/Jul/2009

Title: TRANSACTION CARD WITH MOVABLE MEMBER

Applicant/Assignee: TARGET BRANDS, INC

Application No.: 11/965474   Filing Date: 27/Dec/2007

Abstract:

A transaction card includes a base member, an auxiliary member and an account identifier. The base member defines a first surface, a second surface opposite the first surface and a slot extending therethrough. The auxiliary member includes a first section and a handle section and is coupled with the base member such that the first section is disposed on the first surface of the base member. The handle section extends from the first surface, through the slot and to the second surface of the base member such that movement of the handle section causes movement of the auxiliary member relative to the base member. The account identifier is included on one of the base member and the auxiliary member and links the transaction card to at least one of an account and a record. Other cards, combinations and associated methods are also disclosed.

Priority:

Inventor: REYNOLDS ADAM W [US]; HALBUR TED C [US]; SMITH DENNIS R [US]


Application No.: US20090168388A1  Published: 02/Jul/2009

Title: INTEGRATED CIRCUIT DEVICE AND METHOD OF PRODUCING

Applicant/Assignee: INFINEON TECHNOLOGIES AG

Application No.: 11/964241   Filing Date: 26/Dec/2007

Abstract:

An electronic device which comprises a lead frame comprising at least one clip, a capacitor comprising at least one terminal, the at least one terminal being received in the at least one clip, and a semiconductor chip attached to the lead frame.

Priority:

Inventor: WONG CHEE PENG [MY]; ONG TIAM SEN [MY]; TEE GUAN CHOON [MY]


Application No.: US20090169135A1  Published: 02/Jul/2009

Title: CARRIER BAG, A STACK OF CARRIER BAGS AND A MOUNTING ARRANGEMENT THEREFOR

Applicant/Assignee: EURO PACKAGING LTD

Application No.: 12/096726   Filing Date: 11/Dec/2006

Abstract:

A carrier bag comprising a body having a closed base, closed sides and an open mouth opposite the base, handles extending from the open mouth away from the base, an attachment means extending from or separably connected to the handles and arranged separably to connect the handles together and two mounting member receiving formations, one on each side of the bag, arranged respectively to receive a mounting member of a mounting arrangement. A carrier bag comprising a body having a closed base, closed sides and an open mouth opposite the base, handles extending from the open mouth away from the base, an attachment means extending from or separably connected to the handles and arranged separably to connect the handles together, the attachment means comprising a loop of flexible material extending through apertures in the handles. A carrier bag comprising a body having a closed base, closed sides and an open mouth opposite the base, handles extending from the open mouth away from the base, two mounting member receiving formations, one on each side of the bag, arranged respectively to receive a mounting member of a mounting arrangement, the mounting member receiving formations each comprising a cut or an aperture at a point on the body between the mouth and the base and being formed so as not to create an area of weakness in the body that may cause a failure upon filling or carrying.

Priority: GB20050025097 Applic. Date: 2005-12-09; WO2006GB04619 Applic. Date: 2006-12-11

Inventor: DICKINSON ADAM [GB]


Application No.: US20090169488A1  Published: 02/Jul/2009

Title: Acidic solid oral compositons without erosive potential in saliva and method for determining erosive potential in saliva

Applicant/Assignee: TOMS GRUPPEN A/S

Application No.: 11/658380   Filing Date: 22/Jul/2005

Abstract:

Acidic oral compositions having calcium contents and effective pH-values in the area indicated by grey tone in FIG. 2 are non-erosive in saliva and capable of stimulating saliva production, even in "dry mouth" patients. A new multi-step test method for determining erosive potential in saliva has been used for identifying the compositions.

Priority: DK20040001148 Applic. Date: 2004-07-23; WO2005DK00508 Applic. Date: 2005-07-22

Inventor: JENSDOTTIR THORBJORG [DK]; JENSEN ALLAN BARDOW [DK]; NAUNTOFTE BIRGITTE [DK]; BUCHWALD CHRISTIAN [DK]


Application No.: US20090169491A1  Published: 02/Jul/2009

Title: Peptides Having Activities of Insulin Like Growth Factor-1 and their Uses

Applicant/Assignee: CAREGEN CO., LTD

Application No.: 12/224788   Filing Date: 06/Mar/2007

Abstract:

The present invention relates to a peptide having the activity of insulin like growth factor-1 (IGF-1) and derived from IGF-1, a composition for improving skin conditions or treating a periodontal disease comprising the peptide. The IGF-1 mimicking peptides of this invention have identical functions or actions to natural-occurring IGF-1 and much better stability and skin permeation than natural-occurring IGF-1. In these connections, the composition comprising the peptides of this invention can exhibit excellent efficacies on the treatment, prevention and improvement of diseases or conditions demanding IGF-1 activities. In addition, the peptides of this invention can be advantageously applied to pharmaceutical compositions, quasi-drugs and cosmetics.

Priority: KR20060021099 Applic. Date: 2006-03-06; WO2007KR01086 Applic. Date: 2007-03-06

Inventor: CHUNG YONG JI [KR]; KIM YOUNG DEUG [KR]; KIM EUN MI [KR]


Application No.: US20090169493A1  Published: 02/Jul/2009

Title: Anti-senstivity, anti-caries, anti-staining, anti-plaque, ultra-mild oral hygiene agent

Applicant/Assignee: RHODIA, INC

Application No.: 12/380971   Filing Date: 05/Mar/2009

Abstract:

This invention relates to a composition useful as a dentifrice comprising a surfactant agent consisting essentially of monoalkyl and dialkyl phosphate esters, wherein the ratio of monoesters to diesters is greater than 1, and optionally an abrasive agent consisting essentially of siliceous materials.

Priority: US2004-783721 Applic. Date: 2004-02-20; US20030449128P Applic. Date: 2003-02-21

Inventor: REIERSON ROBERT LEE [US]; DOMKE TODD WILLIAM [US]


Application No.: US20090169590A1  Published: 02/Jul/2009

Title: SYSTEM FOR REDUCING THE NUMBER OF PREDATOR FISH

Applicant/Assignee:

Application No.: 11/964629   Filing Date: 26/Dec/2007

Abstract:

The system includes a capsule member made from a material which is dissolvable in the digestive fluids of a predator fish and at a selected rate in water. The capsule contains a material which, following ingestion by a predator fish, results in death of the predator fish. A connecting element secures the capsule to a prey fish at a selected location on the fish, including the mouth of the fish, and then released into an aqueous environment for ingestion by a predator fish.

Priority:

Inventor: SCOTT BRADFORD L [US]


Application No.: US20090170052A1  Published: 02/Jul/2009

Title: Dental Apparatus for Irrigating Root Canals of Teeth and Method for Irrigating Root Canals of Teeth

Applicant/Assignee:

Application No.: 12/085250   Filing Date: 01/Jan/2007

Abstract:

A dental apparatus for irrigating root canals of teeth comprises a device (1) with an elongated flexible feeder (12) or a flexible pipe introducing a cleansing and/or medical fluid into the root canals of teeth. The device (1) introducing the cleansing and/or medical fluid is moveably inserted in a chamber (5) formed in a head (4) having an angled narrowing (6) with a bush-shaped ending (8) fitted with a duct (13) and connected with the chamber (5) and used to insert the elongated flexible feeder (12). The head (4) is provided with a suction duct (9) connected to the duct (13) near its outlet and carrying at vacuum the cleansing and/or medical fluid flowing out from the root canal to outside of an oral cavity.

Priority: PL20060379300 Applic. Date: 2006-03-27; PL20060380989 Applic. Date: 2006-11-06; WO2007IB50001 Applic. Date: 2007-01-01

Inventor: BORCZYK ROMAN [PL]


Application No.: US20090170812A1  Published: 02/Jul/2009

Title: Transcription factor modulating compounds and methods of use thereof

Applicant/Assignee: PARATEK PHARMACEUTICALS, INC

Application No.: 11/823103   Filing Date: 25/Jun/2007

Abstract:

Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms.

Priority: US20060815984P Applic. Date: 2006-06-23

Inventor: ALEKSHUN MICHAEL N [US]; BARTLETT VICTORIA [US]; GARRITY-RYAN LYNNE [US]; GRIER MARK [US]; KIM OAK K [US]; VERMA ATUL K [US]


Application No.: US20090170838A1  Published: 02/Jul/2009

Title: Bicycloheteroaryl compounds as P2X7 modulators and uses thereof

Applicant/Assignee: RENOVIS, INC

Application No.: 12/218620   Filing Date: 16/Jul/2008

Abstract:

Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

Priority: US2006-384199 Applic. Date: 2006-03-17; US20050664903P Applic. Date: 2005-03-24; US20050709186P Applic. Date: 2005-08-18; US20050710077P Applic. Date: 2005-08-22; US20050712778P Applic. Date: 2005-08-31; US20050721390P Applic. Date: 2005-09-28; US20050753194P Applic. Date: 2005-12-22

Inventor: KELLY MICHAEL G [US]; KINCAID JOHN [US]


Application No.: US20090170873A1  Published: 02/Jul/2009

Title: Pyrazole-substituted arylamides as P2X3 and P2X2/3 antagonists

Applicant/Assignee: ROCHE PALO ALTO LLC

Application No.: 12/317008   Filing Date: 17/Dec/2008

Abstract:

Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted pyrazolyl, and R2, R3, R4, R5, R6, R7 and R8 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.

Priority: US20070007960P Applic. Date: 2007-12-17

Inventor: CHEN LI [CN]; DILLON MICHAEL PATRICK [US]; FENG LICHUN [CN]; HAWLEY RONALD CHARLES [US]; YANG MINMIN [CN]


Application No.: US20090170874A1  Published: 02/Jul/2009

Title: Triazole-substituted arylamides as P2X3 and P2X2/3 antagonists

Applicant/Assignee: ROCHE PALO ALTO LLC

Application No.: 12/317017   Filing Date: 17/Dec/2008

Abstract:

Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted triazolyl, and R2, R3, R4, R5, R6, R7 and R8 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.

Priority: US20070007890P Applic. Date: 2007-12-17

Inventor: CHEN LI [CN]; DILLON MICHAEL PATRICK [US]; FENG LICHUN [CN]; HAWLEY RONALD CHARLES [US]; YANG MINMIN [CN]


Application No.: US20090171158A1  Published: 02/Jul/2009

Title: ENDOSCOPE AND ATTACHING METHOD OF CONNECTION MOUTH RING TO END OF ENDOSCOPIC FLEXIBLE TUBE

Applicant/Assignee:

Application No.: 12/334960   Filing Date: 15/Dec/2008

Abstract:

An endoscope includes a flexible tube having a helical tube in which a thin strip plate is helically wound, a braid tube covering the outside of the helical tube, and a flexible outer tube covering the outside of the braid tube, a connection mouth ring plastically deformed and fixed to an end of the flexible tube, and a helical tube displacement preventing portion which prevents displacement of the strip plate of the helical tube at the end of the flexible tube to which the connection mouth ring is fixed, when the connection mouth ring is fixed to the end of the flexible tube.

Priority: JP20070335326 Applic. Date: 2007-12-26

Inventor: MATSUO SHIGEKI [JP]; UMETA TAKATOSHI [JP]; KOSUKI SHIGERU [JP]


Application No.: US20090171460A1  Published: 02/Jul/2009

Title: ELECTROMECHANICAL SPEECH AID

Applicant/Assignee: SERVONA GMBH

Application No.: 12/296010   Filing Date: 22/Feb/2007

Abstract:

An electromechanical system for the stimulating of vibration of biological tissue, particularly of the human throat tissue, is provided with an electromechanical converter (12) having a self-resonant frequency and being operative for converting electric energy into mechanical energy, designed as a linearly movable, driven element (14) arranged to osculate about a zero-point position or from a zero-point position into a positive or negative direction, and with a vibration surface (20) for acting on the bio-logical tissue. The driven element (14) of the electromechanical converter (12) is supported by an elastic, resilient unit (24) having a self-resonant frequency above the self-resonant frequency of the electromechanical converter (12), whereby the vibration surface (20) is caused to oscillate across a certain frequency range with a swing which at a constant input voltage is substantially constant across the frequency.

Priority: EP20060112214 Applic. Date: 2006-04-04; WO2007EP51723 Applic. Date: 2007-02-22

Inventor: KUPER MARTIN [DE]


Application No.: US20090173654A1  Published: 09/Jul/2009

Title: Merchandising Systems, Methods of Merchandising, and Point-Of-Sale Devices Comprising Micro-Optics Technology

Applicant/Assignee: NANOVENTIONS HOLDINGS, LLC

Application No.: 11/969614   Filing Date: 04/Jan/2008

Abstract:

A merchandising system, including: a consumer product. The merchandising system includes at least one of the consumer product, packaging for the consumer product, and advertisement material pertaining to the consumer product. At least one element of the merchandising system includes indicia and/or an image that relates, or is analogous to, an attribute and/or targeted benefit of the consumer product. At least one element of the merchandising system further includes a micro-optic structure capable of controlling the scatter of light impinging thereon so that the micro-optic structure reflects and/or transmits light in a field of view over which at least a portion of the indicia and/or image appears brighter relative to that outside the field of view.

Priority:

Inventor: STEENBLIK RICHARD A [US]; HURT MARK J [US]; JORDAN GREGORY R [US]; MARTIN BRIAN S [US]; SUSONG JENNIFER [US]


Application No.: US20090175756A1  Published: 09/Jul/2009

Title: NOBLE ALLOY

Applicant/Assignee:

Application No.: 12/244985   Filing Date: 03/Oct/2008

Abstract:

A noble alloy comprising at least 25 wt. % palladium

from 15 to 30 wt. % chromium

at least 5 wt. % molybdenum and/or tungsten

and a principal balance of nickel is provided. Dental products and methods of manufacturing dental products using such a nickel-chromium base noble alloy are also provided.

Priority: US20070977266P Applic. Date: 2007-10-03

Inventor: PRASAD ARUN [US]; CASCONE PAUL J [US]


Application No.: US20090175803A1  Published: 09/Jul/2009

Title: METHOD AND COMPOSITIONS FOR ADMINISTERING RESVERATROL AND PTEROSTILBENE

Applicant/Assignee:

Application No.: 12/350427   Filing Date: 08/Jan/2009

Abstract:

Resveratrol and/or pterostilbene are added to a chewable carrier, to enhance absorption of resveratrol and/or pterostilbene buccally or through the mucous membranes of the mouth. The composition containing the resveratrol and/or pterostilbene is designed to be retained in the mouth for at least 20 seconds and up to 20 minutes to ensure absorption of the resveratrol and/or pterostilbene through the mucous membranes of the mouth.

Priority: US20080019745P Applic. Date: 2008-01-08

Inventor: RUBIN DAVID [US]; RUBIN TAL [US]


Application No.: US20090175805A1  Published: 09/Jul/2009

Title: Neuraminidase Inhibitors and uses thereof

Applicant/Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

Application No.: 12/282759   Filing Date: 13/Mar/2007

Abstract:

The invention is related to various methods for inhibiting or reducing biofilm formation, treating a biofilm production-related disorder, preventing biofilm formation, and screening for neuraminidase inhibitors. The invention also encompasses a mutant bacterial strain with a deleted neuraminidase gene.

Priority: US20060781993P Applic. Date: 2006-03-13; US20060837957P Applic. Date: 2006-08-16; WO2007US06337 Applic. Date: 2007-03-13

Inventor: PRINCE ALICE [US]; TONG LIANG [US]


Application No.: US20090175806A1  Published: 09/Jul/2009

Title: Antimicrobial Compositions Containing Low Concentrations of Botanicals

Applicant/Assignee:

Application No.: 12/367851   Filing Date: 09/Feb/2009

Abstract:

The present invention relates to a preservative or antimicrobial compositions with broad spectrum antimicrobial activity comprising low concentrations of essential oil (and/or one or more component thereof) and a botanical extract in synergistic combination with a fruit acid and alkanediol, and optionally a solvent. The compositions of the invention may be used in personal care products such as creams or soap products.

Priority: WO2008US72006 Applic. Date: 2008-08-01; US20070953654P Applic. Date: 2007-08-02

Inventor: MODAK SHANTA [US]; BAIJU NAYANA [US]; CARAOS LAUSERPINA [US]


Application No.: US20090175997A1  Published: 09/Jul/2009

Title: Reduced calorie sweetener composition

Applicant/Assignee: PHARMED MEDICARE PRIVATE LIMITED

Application No.: 11/658750   Filing Date: 01/Aug/2005

Abstract:

A sweetener composition is described which augments full benefit of reduced calorific value associated through use of high intensity sweeteners as dominant sweetness contributors, and yet avoids problem of loss of favorable organoleptic properties associated with their use by incorporating sugars and other non-sugar low intensity sweeteners in small but an amount enough to provide a correction in organoleptic properties.

Priority: IN2004MU00812 Applic. Date: 2004-07-30; WO2005IN00253 Applic. Date: 2005-08-01

Inventor: RATNAM RAKESH [IN]; AURORA SUNEET [IN]; ZANNONI JOSEPH M [US]


Application No.: US20090176194A1  Published: 09/Jul/2009

Title: METHOD OF CEMENTING PROSTHETIC DEVICES AND CEMENTATION KIT

Applicant/Assignee: KERR CORPORATION

Application No.: 11/969958   Filing Date: 07/Jan/2008

Abstract:

A simplified method for adhering a prosthetic device to tooth structure using a single-part light-curable self-adhering cement composition. The method includes adhering a bonding surface of the prosthetic device to tooth structure directly using a light-curable single-part self-adhering cement composition without first treating the tooth structure and the bonding surface of the prosthetic device with a primer/adhesive, and photo-curing the cement composition. The light-curable single-part self-adhering cement composition comprises: (i) at least one acidic polymerizable monomer having at least one acidic moiety and at least one ethylenically unsaturated group, (ii) at least one non-acidic polymerizable monomer having at least one ethylenically unsaturated group, (iii) at least one photo-initiator, and (iv) at least one filler. The weight ratio of component (i) to component (ii) ranges from about 0.5:99.5 to about 70:30.

Priority:

Inventor: QIAN XUEJUN [US]


Application No.: US20090176743A1  Published: 09/Jul/2009

Title: Methods for treating or preventing reactivation of a latent herpesvirus infection

Applicant/Assignee:

Application No.: 11/989700   Filing Date: 31/Jul/2006

Abstract:

The invention is directed to methods and compositions for treating or preventing reactivation of a latent herpesvirus infection and the associated complications and outcomes. The methods involve administering a composition comprising glutamine, or a derivative, conjugate, or analog thereof.

Priority: US20050703835P Applic. Date: 2005-07-29; WO2006US29663 Applic. Date: 2006-07-31

Inventor: SCHAFFER PRISCILLA [US]; BRINGHURST RYAN [US]


Application No.: US20090176883A1  Published: 09/Jul/2009

Title: TRPA1 Antagonists

Applicant/Assignee: ABBOTT LABORATORIES

Application No.: 12/348064   Filing Date: 02/Jan/2009

Abstract:

Compounds of formula (I) wherein R1, R2, R3, m, and Y are defined in the specification are TRPA1 antagonists. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

Priority: US20080019021P Applic. Date: 2008-01-04

Inventor: PERNER RICHARD J [US]; KORT MICHAEL E [US]; DIDOMENICO STANLEY [US]; CHEN JUN [US]; VASUDEVAN ANIL [US]


Application No.: US20090176891A1  Published: 09/Jul/2009

Title: DENTAL COMPOSITION AND METHOD OF USE

Applicant/Assignee:

Application No.: 12/330144   Filing Date: 08/Dec/2008

Abstract:

A dental composition for sealing a portion of a tooth includes a liquid acrylic or acrylate monomer, an acrylic or acrylate polymer that is soluble in the liquid acrylic or acrylate monomer, a photo-initiator for cross-linking the liquid acrylic or acrylate monomer, and a nanoparticle material dispersed within the composition.

Priority: US20070992875P Applic. Date: 2007-12-06

Inventor: CHOGLE SAMI [US]; SHAIKH SOHEL [US]; MICKEL ANDRE [US]; QUTUBUDDIN SYED [US]; SANKARAN MOHAN [US]


Application No.: US20090178188A1  Published: 16/Jul/2009

Title: On-Tank Toilet Dispenser

Applicant/Assignee:

Application No.: 12/354129   Filing Date: 15/Jan/2009

Abstract:

Disclosed is a dispenser for dispensing a composition in response to level changes in a liquid in a tank. The dispenser includes a container for holding the composition, a discharge conduit in fluid communication with the container, an air inlet in fluid communication with the container, and a level sensing member mounted to the dispenser such that a lower end of the level sensing member contacts the liquid in the tank and senses its level. In use, a rise of the liquid in the tank between a lower liquid level and a higher liquid level causes the level sensing member to alter air pressure in a headspace of the container above the composition and thereby cause a controlled discharge of the composition from the discharge conduit

and a fall of the liquid in the tank between the higher liquid level and the lower liquid level causes the level sensing member to alter pressure in the headspace and thereby causing air to be vented into the headspace from the air inlet.

Priority: US20080021099P Applic. Date: 2008-01-15

Inventor: CAMPAU DANIEL N [US]; FRYAN MICHAEL C [US]; ZACH STEVEN A [US]; SOLLER DOUGLAS A [US]


Application No.: US20090178219A1  Published: 16/Jul/2009

Title: ORAL CARE TOOTHBRUSH

Applicant/Assignee: COLGATE-PALMOLIVE

Application No.: 12/334562   Filing Date: 15/Dec/2008

Abstract:

An oral care toothbrush includes a head mounted to one end of the handle containing a plurality of oral care elements. An oral care accessory is mounted to the opposite end of the handle. An oral care material dispenser is mounted in the head within the cleaning field defined by the oral care elements. The toothbrush is preferably made of small size and of lightweight so as to be readily portable for use away from the home.

Priority: US2005-314716 Applic. Date: 2005-12-21; US2004-843135 Applic. Date: 2004-05-11; WO2003US27455 Applic. Date: 2003-09-04; US20050231483F Applic. Date: 2005-06-06; US20040213754F Applic. Date: 2004-09-23; US20050231487F Applic. Date: 2005-06-06; US20020408321P Applic. Date: 2002-09-05

Inventor: HOHLBEIN DOUGLAS J [US]


Application No.: US20090178679A1  Published: 16/Jul/2009

Title: Cushion for a respiratory mask assembly

Applicant/Assignee: RESMED LIMITED

Application No.: 12/382517   Filing Date: 18/Mar/2009

Abstract:

A respiratory mask includes a frame including a breathable gas port, wherein the frame defines an inner chamber to receive at least one of a wearer's nasal region and mouth. The mask includes a cushion including a flange connected to the frame, an inner rim defining an opening to the inner chamber of the frame, and a sealing portion disposed between the flange and the inner rim to contact the wearer's face. The sealing portion includes a nasal seal section to span a wearer's face above the wearer's nares, side seal sections extending from each side of the nasal seal section on both sides of the wearer's mouth, and a chin seal section that extends between the side seal sections. The chin seal section is upwardly curved in an arch to follow the chin's bony contour.

Priority: US2003-655622 Applic. Date: 2003-09-05; US2002-235846 Applic. Date: 2002-09-06; US20020424686P Applic. Date: 2002-11-08; US20030483622P Applic. Date: 2003-07-01; US20010317486P Applic. Date: 2001-09-07; US20010342854P Applic. Date: 2001-12-28

Inventor: LITHGOW PERRY DAVID [AU]; FRATER ROBERT HENRY [AU]; DREW JOANNE ELIZABETH [AU]; GUNEY MEMDUH [AU]; FU TIMOTHY TSUN-FAI [AU]; KWOK PHILIP RODNEY [AU]


Application No.: US20090179036A1  Published: 16/Jul/2009

Title: Hermetically Sealed Liquid-Containing Bag With Welded-In Drinking or Dispensing Spout

Applicant/Assignee:

Application No.: 12/085478   Filing Date: 23/Nov/2006

Abstract:

The liquid-containing bag is produced integrally from two sheets (4

5) which are welded to on another along the edge region (3), and the bag forms two chambers (6

7) which are separated from one another by a separating strip (8). A drinking or dispensing spout (2) is welded with sealing action in the separating strip (8), in which case this connects the two chambers (6, 7) in the open state, the one bag chamber (6) being intended for receiving the liquid, while the other bag chamber (7), as a protective chamber, encompasses the outer spout end (9) and encloses the same with sealing action.

Priority: CH20050001880 Applic. Date: 2005-11-25; WO2006CH00657 Applic. Date: 2006-11-23

Inventor: SEELHOFER FRITZ [CH]


Application No.: US20090180118A1  Published: 16/Jul/2009

Title: Method of optically monitoring the progression of a physical and/or chemical process taking place on a surface of a body

Applicant/Assignee: IVOCLAR VIVADENT AG

Application No.: 12/220896   Filing Date: 29/Jul/2008

Abstract:

The invention relates to a method for optically monitoring the progression of a physical and/or chemical process taking place on a surface of a body in which the surface radiation which emanates from part of the surface during the physical and/or chemical process, is measured with the aid of a measuring device, in particular a sensor. In order to develop a method of this kind such that sintering processes can also be monitored in a firing furnace having thermal radiation equilibrium, the invention proposes to emit the radiation (14) having a radiation spectrum that differs from the surface radiation, to the surface (10) by means of a radiation source (15) and to measure the radiation with the aid of a measuring device (16).

Priority: DE200710035609 Applic. Date: 2007-07-30

Inventor: FEICHTINGER HEINRICH [CH]; ROHNER GOTTFRIED [CH]; JUSSEL RUDOLF [AT]


Application No.: US20090180899A1  Published: 16/Jul/2009

Title: DEVICE, AND METHOD FOR FEEDING SUBSTANCES

Applicant/Assignee: FYDEC HOLDING SA

Application No.: 12/278271   Filing Date: 30/Jan/2007

Abstract:

An apparatus for pumping free-flowing materials, having a receptacle coupled to a vacuum pipe and a pumping gas pipe, at least one filter, at least one supply pipe, and at least one drainage pipe for a material being associated with the receptacle. The apparatus includes a vertically extending cylindrical pump chamber configured to pneumatically pump liquids, powder, suspensions and pastes. Further, a device is mounted in an upper region of the pump chamber configured to separate liquid and powder. The device further includes a filter element and a float member. The float member is configured as a sealing element above, and a lower region of the pump chamber is coupled to the at least one supply pipe and the at least one drainage pipe for at least one of a liquid, a powder, a suspension, and a paste.

Priority: DE200610005190 Applic. Date: 2006-02-02; DE200610007277 Applic. Date: 2006-02-15; WO2007EP00782 Applic. Date: 2007-01-30

Inventor: DIETRICH FREDERIC JUN [CH]


Application No.: US20090180923A1  Published: 16/Jul/2009

Title: SELF-MIXING CONTAINER WITH A RELEASABLE INTERNAL VESSEL AND ITS USAGE

Applicant/Assignee:

Application No.: 12/160294   Filing Date: 16/Jan/2007

Abstract:

This application relates to a self-mixing container with a releasable internal vessel and its usage, wherein said self-mixing container comprises a container body, a double-walled external cap and an internal vessel, and through a corresponding production line, assembling of the self-mixing container with a releasable internal vessel will be realized. The invention makes it possible to pack and seal in a cold filling process at least two different materials in one and the same container body respectively. When in use, at least two kinds of materials are mixed and formulated in one and the same container body in a rapid and automatic way, by means of relative movement of the screw-threads by which the container body, the double-walled external cap and the internal vessel are coupled with each other, and engagement of the ratchet and the pawls, without the structure of the container body being damaged, so that initial fresh active components in the materials sealed therein are preserved, and rapid formulation is achieved. Furthermore, the structure is simple, durable and has a low fabrication cost, and it can be used without great effort or time, especially can be used conveniently when carried on, and it can be broadly applied to pharmaceutical, food and beverage, chemical, farm chemical, disinfectants, or fire-fighting equipments field.

Priority: CN20062095128U Applic. Date: 2006-01-17; CN20062096721U Applic. Date: 2006-05-17; CN20062098537U Applic. Date: 2006-08-16; WO2007CN00158 Applic. Date: 2007-01-16

Inventor: GONG XIAO [CN]


Application No.: US20090181957A1  Published: 16/Jul/2009

Title: BENZIMIDAZOLONE DERIVATIVES AS CB2 RECEPTOR LIGANDS

Applicant/Assignee:

Application No.: 11/909763   Filing Date: 02/Mar/2006

Abstract:

This invention relates to compounds of the formula (I): or pharmaceutically acceptable salts thereof, wherein: A, B, R1, R2 and R3 are each as described herein, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by CB2 receptor binding activity such as, but not limited to, inflammatory pain, nociceptive pain, neuropathic pain, fibromyalgia, chronic low back pain, visceral pain, acute cerebral ischemia, pain, chronic pain, acute pain, post herpetic neuralgia, neuropathies, neuralgia, diabetic neuropathy, HIV-related neuropathy, nerve injury, rheumatoid arthritic pain, osteoarthritic pain, back pain, cancer pain, dental pain, fibromyalgia, neuritis, sciatica, inflammation, neurodegenerative disease, cough, broncho constriction, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), colitis, cerebrovascular ischemia, emesis such as cancer chemotherapy-induced emesis, rheumatoid arthritis, asthma, Crohn's disease, ulcerative colitis, asthma, dermatitis, seasonal allergic rhinitis, gastroesophageal reflux disease (GERD), constipation, diarrhea, functional gastrointestinal disorder, cutaneous T cell lymphoma, multiple sclerosis, osteoarthritis, psoriasis, systemic lupus erythematosus, diabetes, glaucoma, osteoporosis, glomerulonephritis, renal ischemia, nephritis, hepatitis, cerebral stroke, vasculitis, myocardial infarction, cerebral ischemia, reversible airway obstruction, adult respiratory disease syndrome, chronic obstructive pulmonary disease (COPD), cryptogenic fibrosing alveolitis or bronchitis.

Priority: US20050662183P Applic. Date: 2005-03-15; WO2006IB00521 Applic. Date: 2006-03-02

Inventor: ANDO KAZUO [JP]; KAWAI MAKOTO [JP]; MASUDA TSUTOMU [JP]; OMURA HIROFUMI [JP]


Application No.: US20090182109A1  Published: 16/Jul/2009

Title: Radical polymerizable macrocyclic resin compositions with low polymerization stress

Applicant/Assignee:

Application No.: 12/381781   Filing Date: 16/Mar/2009

Abstract:

A composition of macrocyclic oligomer with at least one (meth)acrylate polymerizable group. A method includes preparing an activated precursor of an oligomer at pseudo high-dilution conditions. A method also includes preparing an activated precursor of an oligomer by reacting the precursor with an activated coupling agent, wherein the precursor is condensable and polymerizable.

Priority: US2008-079525 Applic. Date: 2008-03-27; US2005-153090 Applic. Date: 2005-06-15; US20040579836P Applic. Date: 2004-06-15

Inventor: JIN XIAOMING [US]; HAMMESFAHR PAUL D [US]


Application No.: US20090182364A1  Published: 16/Jul/2009

Title: TONGUE RETRACTION AND CLEANING METHOD AND APPARATUS

Applicant/Assignee:

Application No.: 12/013911   Filing Date: 14/Jan/2008

Abstract:

One embodiment includes an apparatus for retracting an animal tongue that includes a handle that is elongate and that includes a proximal portion and a distal portion and a tongue receiving cup coupled to the distal portion of the handle, the tongue receiving cup being generally concave and sized such that a first side of the tongue receiving cup extends over a first side of the tongue, a second side opposite the first side extends over a second side of the tongue that is opposite the first side of the tongue, a dorsal portion of the cup extends along the dorsal portion of the tongue and a posterior extending tip extends at least partially along the back of the tongue, the first side, second side, and posterior extending tip defining a tongue receiving cavity of the tongue receiving cup.

Priority:

Inventor: METTLER JR GILBERT WILLIAM [US]


Application No.: US20090183739A1  Published: 23/Jul/2009

Title: METHODS AND DEVICES FOR IMPROVING EFFICACY OF NON-INVASIVE VENTILATION

Applicant/Assignee: MENLOLIFE, INC

Application No.: 12/355753   Filing Date: 16/Jan/2009

Abstract:

A nasal ventilation interface including a manifold a nasal cushions. The manifold is configured with compound arcuate curves for optimizing fit and performance. The ventilation gas supply hose is attached to only one side of the manifold at any given time, thereby freeing up the opposite side of the user's face to enhance comfort and tolerance while sleeping.

Priority: US20080006548P Applic. Date: 2008-01-18; US20080106414P Applic. Date: 2008-10-17

Inventor: WONDKA ANTHONY D [US]


Application No.: US20090184085A1  Published: 23/Jul/2009

Title: Tape for mass-sealing bottles and similar containers, and apparati for its application and removal

Applicant/Assignee:

Application No.: 12/383570   Filing Date: 25/Mar/2009

Abstract:

A composite laminar tape (1) for mass-sealing bottles (15) or similar containers consists, according to the invention, of at least one extensible laminar tape (16), made of an extensible plastomeric film, which is possibly provided with closed lines for a predetermined separation of areas being meant to act as sealing membranes. The invention also relates to an apparatus for mass-sealing containers with said tape, and to an apparatus for mass-unsealing the containers sealed with said tape.

Priority: CH19970000166 Applic. Date: 1997-01-27; IT1997MI01013 Applic. Date: 1997-04-30; US2003-440269 Applic. Date: 2003-05-19; US1999-355392 Applic. Date: 1999-08-09; WO1998EP00354 Applic. Date: 1998-01-23

Inventor: RIBI LEON ANTOINE [SZ]


Application No.: US20090184893A1  Published: 23/Jul/2009

Title: Portable LCD TV

Applicant/Assignee:

Application No.: 12/017073   Filing Date: 21/Jan/2008

Abstract:

A portable, sturdy LCD TV is disclosed. The LCD TV is further constructed as a waterproof device and is equipped with an antenna so that the LCD TV, in addition to be used indoors as a computer monitor or TV, is also suitable for outdoor use.

Priority:

Inventor: YANG TIEN DENG [TW]


Application No.: US20090185851A1  Published: 23/Jul/2009

Title: Interior Vehicle Windshield Window Cleaning Kit

Applicant/Assignee:

Application No.: 12/017209   Filing Date: 21/Jan/2008

Abstract:

A complete portable lightweight interior vehicle windshield/window cleaning kit that sits on the dash-board on any vehicle for use at anytime. This windshield/window cleaning kit cleans the interior windshield/windows on the vehicle. This interior vehicle windshield/window cleaning kit is housed within the body of different shapes, colors and sized animal creations. The synthetic filled animal creations will be different from all others, by having workable cleaning tools housed within its torso. Encased within the torso will be a squeegee, spray bottle for cleaning solution and a towel to wipe off excess fluid from the windshield/windows. This complete interior vehicle windshield/windows cleaning kit will be an improvement over other auto glass windshield cleaning devices, as this interior vehicle windshield/window cleaning kit will be accessible at all times to the driver by being of a size that it can be stored on the dashboard, on the console or in glove compartment.

Priority:

Inventor: MAPALO CORDELLIA [US]; CAROTHERS DON [US]


Application No.: US20090185984A1  Published: 23/Jul/2009

Title: COLORANTS SURFACE TREATED WITH URETHANES AND METHODS FOR MAKING AND USING THE SAME

Applicant/Assignee: SENSIENT COLORS INC

Application No.: 12/299144   Filing Date: 12/Oct/2006

Abstract:

Compositions including colorants surface-treated with silicone polyurethanes, and methods for making surface-treated colorant products, are provided. Cosmetic, . . . personal care, skin care, nail and hair products including the surface treated colorants are disclosed. Also provided are methods for improving the hydrophobicity, or the adherence to the surface of skin, of a colorant. The methods include surface-treating a colorant with an effective amount of a silicone polyurethane to form a surface-treated colorant having an improved hydrophobilicy or an improved adherence to a skin surface compared to the colorant before surface-treatment.

Priority: US20060796370P Applic. Date: 2006-05-01; US20060806189P Applic. Date: 2006-06-29; WO2006US39994 Applic. Date: 2006-10-12

Inventor: GUTKOWSKI GLENN A [US]; THYS WILLIAM F [US]


Application No.: US20090185985A1  Published: 23/Jul/2009

Title: LARGE-PARTICLE CYCLODEXTRIN INCLUSION COMPLEXES AND METHODS OF PREPARING SAME

Applicant/Assignee: CARGILL, INCORPORATED

Application No.: 12/302551   Filing Date: 05/Dec/2006

Abstract:

The present invention provides a cyclodextrin inclusion complex comprising a guest encapsulated by cyclodextrin, the complex being greater than about 400 microns in size and methods of making the same. The present invention also provides a method of imparting flavor to a product to form a flavored product, the method comprising: incorporating a large particle cyclodextrin inclusion complex into a product to form a flavored product, the complex comprising a guest encapsulated by a cyclodextrin. The present invention further provides a flavored product comprising a large particle cyclodextrin inclusion complex.

Priority: US20060813019P Applic. Date: 2006-06-13; WO2006US46480 Applic. Date: 2006-12-05

Inventor: STRASSBURGER KENNETH J [US]


Application No.: US20090185987A1  Published: 23/Jul/2009

Title: HERBAL DENTAL CARE COMPOSITION, METHOD OF MANUFACTURING THE SAME AND USE THEREOF

Applicant/Assignee: HIMALAYA GLOBAL HOLDINGS LTD

Application No.: 12/139262   Filing Date: 13/Jun/2008

Abstract:

Disclosed herein is a herbal dental care composition comprising extracts of herbs Punica granatum, Acacia Arabica, Terminalia chebula, Terminalia bellerica, Emblica officinalis and Embelia ribes, optionally extract of Azadirachta indica and pharmaceutical acceptable excipients. Also disclosed are the methods of making the composition, formulating the same into different delivery systems and use thereof for preventing various dental diseases.

Priority: IN2008DE00167 Applic. Date: 2008-01-21

Inventor: MITRA SHANKAR KUMAR [IN]; SURIYANARAYANAN RAMESH [IN]; BABU UDDAGIRI VENKANNA [IN]; SAXENA EKTA [IN]


Application No.: US20090186080A1  Published: 23/Jul/2009

Title: METHODOLOGY AND APPARATUS FOR ORAL DUAL DELIVERY OF HOMEOPATHIC PRODUCTS AND NON-HOMEOPATHIC PRODUCTS

Applicant/Assignee: BANKS HOLDING COMPANY, INC

Application No.: 12/357292   Filing Date: 21/Jan/2009

Abstract:

One possible embodiment of the invention may be an oral dosage apparatus comprising of a sealed, digestible container having an exterior that defines and seals a respective interior

the interior containing one or more non-homeopathic remedies

and the exterior presenting one or more homeopathic products. Another version of the invention may be a method of manufacturing an oral dosage apparatus comprising of the following steps of providing one or more non-homeopathic remedies and one or more non-homeopathic remedies

providing a sealed, digestible container having an exterior that correspondingly defines and seals a respective interior containing one or one or more non-homeopathic remedies

affixing one or more homeopathic remedies to the exterior.

Priority: US20080022402P Applic. Date: 2008-01-21

Inventor: BANKS BRIAN S [US]


Application No.: US20090186090A1  Published: 23/Jul/2009

Title: Oral Care Composition to Reduce or Eliminate Dental Sensitivity

Applicant/Assignee: COLGATE-PALMOLIVE

Application No.: 12/356837   Filing Date: 21/Jan/2009

Abstract:

The invention includes an oral care composition that reduces and/or eliminates the perception of tooth sensitivity. The composition includes an adherent material and includes, in part, particles having a particle size of 2-5 microns. Also included within the scope of the invention are methods comprising the use of such compositions, such as methods of reducing dental sensitivity.

Priority: US2008-339598 Applic. Date: 2008-12-19; US2008-103919 Applic. Date: 2008-04-16; US2007-742039 Applic. Date: 2007-04-30

Inventor: ZAIDEL LYNETTE [US]; CHOPRA SUMAN K [US]; PRENCIPE MICHAEL [US]; WANG QIN [US]; CHRISTOPOULOU CONSTANTINA [US]


Application No.: US20090186189A1  Published: 23/Jul/2009

Title: Hydroentangled Product Comprising Cellulose Fibers

Applicant/Assignee: LENZING AKTIENGESELLSCHAFT

Application No.: 12/298079   Filing Date: 26/Apr/2007

Abstract:

The present invention relates to a process for the production of a hydroentangled product comprising cellulose fibers, which includes the steps of (a) extruding a solution comprising cellulose dissolved in an aqueous tertiary amine-oxide through a spinneret into an air gap, thereby forming filaments (b) drawing said filaments by means of a gaseous stream (c) collecting and precipitating said filaments in order to form a web (d) bonding said web by means of a hydroentanglement process (e) contacting said filaments in the air gap with a medium which at least partially coagulates the filaments. Furthermore, the invention relates to products obtainable by said products, and uses thereof.

Priority: AT20060000728 Applic. Date: 2006-04-28; WO2007AT00192 Applic. Date: 2007-04-26

Inventor: WHITE PAT [GB]; HARMS HAIO [AT]; HAYHURST MALCOLM [GB]


Application No.: US20090186313A1  Published: 23/Jul/2009

Title: Metallic dental devices with tooth colors and their preparation methods

Applicant/Assignee: NATIONAL TSING HUA UNIVERSITY CHANG-GUNG MEMORIAL HOSPITAL

Application No.: 12/314952   Filing Date: 19/Dec/2008

Abstract:

Metallic devices are frequently used in dental treatments, such as orthodontic archwires, rackets, or dental mini-screws. This invention provides metallic dental devices with a color of tooth or close to tooth, and their preparation methods.

Priority: TW20080102412 Applic. Date: 2008-01-22

Inventor: CHEN SINN-WEN [TW]; WU HSIN-JAY [TW]; HUANG LI-LING [TW]; LIOU ERIC JEIN-WEIN [TW]


Application No.: US20090187243A1  Published: 23/Jul/2009

Title: BIOCOMPATIBLE COPPER-BASED SINGLE-CRYSTAL SHAPE MEMORY ALLOYS

Applicant/Assignee:

Application No.: 12/325722   Filing Date: 01/Dec/2008

Abstract:

We describe herein biocompatible single crystal Cu-based shape memory alloys (SMAs). In particular, we show biocompatibility based on MEM elution cell cytotoxicity, ISO intramuscular implant, and hemo-compatibility tests producing negative cytotoxic results. This biocompatibility may be attributed to the formation of a durable oxide surface layer analogous to the titanium oxide layer that inhibits body fluid reaction to titanium nickel alloys, and/or the non-existence of crystal domain boundaries may inhibit corrosive chemical attack. Methods for controlling the formation of the protective aluminum oxide layer are also described, as are devices including such biocompatible single crystal copper-based SMAs.

Priority: US20070991634P Applic. Date: 2007-11-30

Inventor: JOHNSON ALFRED DAVID [US]


Application No.: US20090187997A1  Published: 23/Jul/2009

Title: Cre-lox based gene knockdown constructs and methods of use thereof

Applicant/Assignee:

Application No.: 12/076001   Filing Date: 12/Mar/2008

Abstract:

The present invention relates to vectors, compositions and methods for conditional, Cre-lox regulated, RNA interference. The vectors allow for spatial and temporal control of miRNA expression in vivo.

Priority: US20070906511P Applic. Date: 2007-03-13; US20070935154P Applic. Date: 2007-07-27

Inventor: STERN PATRICK [US]; HYNES RICHARD [US]


Application No.: US20090188067A1  Published: 30/Jul/2009

Title: ATTACHMENT FOR A CLEANING APPLIANCE

Applicant/Assignee: DYSON TECHNOLOGY LIMITED

Application No.: 12/282122   Filing Date: 01/Mar/2007

Abstract:

An attachment for a cleaning appliance includes a head including a suction opening and a neck including an intermediate portion and an end portion for connection to the mouth of a wand or hose having a longitudinal axis. The attachment also includes a first rotatable connection located between the end portion and the intermediate portion having a first axis of rotation and a second rotatable connection located between the head and the intermediate portion having a second axis of rotation. Each rotatable connection allows relative movement of the end portion with respect to the head. The first axis of rotation is inclined with respect to the longitudinal axis of the end portion. By providing such an attachment for a cleaning appliance, the head of the attachment can be moved into a variety of useful positions to allow easier cleaning of walls and high-level horizontal surfaces.

Priority: GB20060004654 Applic. Date: 2006-03-08; WO2007GB00730 Applic. Date: 2007-03-01

Inventor: WHITE WILLIAM ROBERT JAMES [GB]; WISHNEY ADAM ANDREW [GB]


Application No.: US20090190864A1  Published: 30/Jul/2009

Title: AIRTIGHT EVACUABLE STORAGE BAG AND RELATED METHOD OF MANUFACTURE

Applicant/Assignee: ILLINOIS TOOL WORKS INC

Application No.: 12/361334   Filing Date: 28/Jan/2009

Abstract:

Methods for manufacturing airtight storage containers (e.g., bags or pouches) made from thermoplastic web material and having heat-sealed margins along a perimeter. To ensure that the storage containers are airtight, an unheated rib is pressed along each heat seal while the web material in the region of each heat seal is still in a softened and pliable state. As a result of the pressure applied, the rib deforms the contacted portion of the heat-sealed web material, leaving an indentation upon cooling of the web material that serves as an air leakage barrier. This air leakage barrier ensures that any air leakage pathway across the heat seal region is closed.

Priority: US20080024664P Applic. Date: 2008-01-30

Inventor: CALVO MARTIN [US]; PHAM LINH [US]


Application No.: US20090191127A1  Published: 30/Jul/2009

Title: OMENTUM AND USE THEREOF

Applicant/Assignee:

Application No.: 12/361808   Filing Date: 29/Jan/2009

Abstract:

In some embodiments, mammalian omentum and methods of using the same for treating symptoms and/or conditions related to dementia are provided. In addition, a composition comprising the omentum tissue and/or the extract thereof is described in some embodiments. In some other embodiments, methods of formulating and administering the composition are also provided. In addition, a cultured cell system to culture cells and/or tissues of the omentum is described. Some aspects of embodiments provide methods of identifying one or more biological agent from the omentum tissue. In another aspect of the embodiments, methods of testing the effect of stimulation omentum in treating dementia conditions are described.

Priority: WO2009US31462 Applic. Date: 2009-01-20; US20080023840P Applic. Date: 2008-01-26; US20080113937P Applic. Date: 2008-11-12

Inventor: SAINI SURINDER SINGH [US]


Application No.: US20090191258A1  Published: 30/Jul/2009

Title: IODINE-CONTAINING COMPOSITIONS

Applicant/Assignee:

Application No.: 12/359681   Filing Date: 26/Jan/2009

Abstract:

Compositions provided according to embodiments of the present invention include an inorganic clay admixed with an iodine-containing substance. Suitable iodine-containing substances include I2 and/or one or more iodine salts. Methods of treating a condition or disorder are provided according to the present invention which include administration of a therapeutically effective amount of a composition including an inorganic clay admixed with an iodine-containing substance to an affected subject. Optionally, the composition is administered in an article of manufacture to the affected area.

Priority: US20080023192P Applic. Date: 2008-01-24

Inventor: MANKOVITZ ROY J [US]


Application No.: US20090191505A1  Published: 30/Jul/2009

Title: Dental Matrix Devices Specific To Anterior Teeth, and Injection Molded Filling Techniques and Devices

Applicant/Assignee:

Application No.: 12/362280   Filing Date: 29/Jan/2009

Abstract:

The present invention relates to methods for the restoration of a decayed portion of an anterior tooth or re-restoration of a previously filled anterior tooth, and to dental matrices and composite resin dispensers that may be used in the methods for the restoration of a decayed portion of an anterior tooth

Priority: US20080024473P Applic. Date: 2008-01-29; US20080043307P Applic. Date: 2008-04-08

Inventor: CLARK DAVID J [US]


Application No.: US20090191507A1  Published: 30/Jul/2009

Title: IMPLANT SURFACE WITH INCREASED HYDROPHILICITY

Applicant/Assignee: BIOMET 3I, LLC

Application No.: 12/359780   Filing Date: 26/Jan/2009

Abstract:

A method of increasing the hydrophilicity of an implant to be implanted into living bone. The method comprises the act of depositing non-toxic salt residuals on the surface of the implant by exposing the surface to a solution including the non-toxic salts. The method further comprises the act of drying the implant.

Priority: US20080137293P Applic. Date: 2008-07-28; US20080062577P Applic. Date: 2008-01-28

Inventor: CHARLTON JACQUELINE K [US]; MAYFIELD ROBERT L [US]; TOWSE ROSS W [US]


Application No.: US20090191510A1  Published: 30/Jul/2009

Title: Periodontal treatment employing applied ultrasonic energy

Applicant/Assignee: CAO GROUP, INC

Application No.: 11/473383   Filing Date: 22/Jun/2006

Abstract:

A method for treating periodontal disease. A dental substance is applied to gingival tissues by use of ultrasonic energy for improved exposure and treatment results.

Priority: US20050692720P Applic. Date: 2005-06-22

Inventor: LARSEN ROBERT K [US]


Application No.: US20090192239A1  Published: 30/Jul/2009

Title: POLYMERIZABLE COMPOSITIONS CONTAINING SALTS OF BARBITURIC ACID DERIVATIVES

Applicant/Assignee:

Application No.: 12/302591   Filing Date: 31/May/2007

Abstract:

This invention relates to polymerizable compositions comprising a salt of a barbituric acid derivative. The compositions are typically shelf-life stable and may be polymerized through mixing of an acidic component with the salt of a barbituric acid derivative.

Priority: EP20060011176 Applic. Date: 2006-05-31; WO2007US70031 Applic. Date: 2007-05-31

Inventor: HECHT REINHOLD [DE]; LUDSTECK MANFRED [DE]; RAIA GIOACCHINO [DE]; OXMAN JOEL D [US]


Application No.: US20090192721A1  Published: 30/Jul/2009

Title: METABOLIC PHENOTYPING

Applicant/Assignee: PFIZER INC

Application No.: 12/233996   Filing Date: 20/Nov/2008

Abstract:

A method of generating models with which to characterise selected aspects of the metabolic phenotype of subjects without dosing a test substance to those subjects or with which to predict, without dosing, the post-dose responses of subjects where those responses are dependent on metabolic phenotype, the method comprising: obtaining pre-dose data relating to a plurality of subjects before dosing with a dosing substance

obtaining post-dose data relating to the plurality of subjects after dosing with the dosing substance

and correlating inter-subject variation in the pre-dose data with inter-subject variation in the post-dose data, and generating a pre-to-post-dose predictive model on the basis of the observed correlation. The models may be used to determine selected aspects of the metabolic phenotype of a subject or to predict, without dosing, the post-dose responses of subjects. This is achieved by analysing data relating to the un-dosed subject in relation to a model describing the correlation of pre-dose and post-dose data relating to a plurality of subjects when dosed with a particular substance which challenges the biochemical transformation or pathway of interest

Priority: GB20020013786 Applic. Date: 2002-06-14; GB20020013895 Applic. Date: 2002-06-17; US2004-755061 Applic. Date: 2004-01-08

Inventor: CLAYTON THOMAS ANDREW [NA]; EVERETT JEREMY RAMSEY [NA]; LINDON JOHN CHRISTOPHER [NA]; NICHOLSON JEREMY KIRK [NA]


Application No.: US20090194093A1  Published: 06/Aug/2009

Title: BAFFLE-TYPE GREASE FILTERS FOR KITCHEN VENTILATORS

Applicant/Assignee: FRANKLIN MACHINE PRODUCTS

Application No.: 12/023178   Filing Date: 31/Jan/2008

Abstract:

A grease filter has upper and lower baffle assemblies that define tortuous paths for exhaust air flowing therethrough. The baffles in the upper assembly include a perforated metal strips and bent free edges to maximize grease extraction from the exhaust air. A hinge connects the upper and lower baffle assemblies and permits the assemblies to pivot from a closed position to an open position. In the open position, access is provided to all surfaces of the assemblies so that they can be efficiently cleaned.

Priority:

Inventor: AVILES JOSUE V [US]


Application No.: US20090194132A1  Published: 06/Aug/2009

Title: DENTAL FLOSSER HAVING MULTI-TEXTURE FLOSS

Applicant/Assignee:

Application No.: 12/363997   Filing Date: 02/Feb/2009

Abstract:

A dental flosser having a handle and a pair of spaced apart arms. A length of dental floss having distinct segments of varying textures extends between the spaced apart arms. A first segment is relatively smooth and is used for insertion and withdrawal of the floss into/from the spaces between adjacent teeth. A second segment is textured and is used for removing plaque and other debris from the spaces between adjacent teeth.

Priority: US20080024959P Applic. Date: 2008-01-31; US20080024955P Applic. Date: 2008-01-31

Inventor: KALBFELD RUSSELL G [US]; BARCUS DAVID L [US]


Application No.: US20090194134A1  Published: 06/Aug/2009

Title: MULTI-TEXTURE FLOSS AND METHODS OF MANUFACTURING MULTI-TEXTURE FLOSS

Applicant/Assignee:

Application No.: 12/355497   Filing Date: 16/Jan/2009

Abstract:

A multi-texture dental floss includes distinct and alternating segments having varying textures, including smooth segments and textured segments. The smooth segments are more easily inserted into the spaces between teeth, while the textured segments more effectively remove plaque and other debris therefrom. Methods of making the multi-texture floss are also disclosed, including methods that allow the floss to be made as a continuous thread having a plurality of alternating segments, such that the floss can be wound onto a spool for storage and dispensing.

Priority: US20080024955P Applic. Date: 2008-01-31

Inventor: KALBFELD RUSSELL G [US]; BARCUS DAVID L [US]


Application No.: US20090195385A1  Published: 06/Aug/2009

Title: Proactive hand hygiene monitoring system

Applicant/Assignee:

Application No.: 12/217415   Filing Date: 03/Jul/2008

Abstract:

A system consists of remote identification tag (in the form of wristband) for personnel who must undergo hand hygiene frequently during a day's work, programmed soap and rinse-free disinfectant dispensers, entry-exit sensors for controlled access areas and data transfer stations is used to monitor and record every handwashing procedure along with its thoroughness as well as every hand cleaning event with rinse-free disinfectant. The system will further prompt each worker's identification tag at an appropriate place to examine its record to see whether a hand hygiene procedure is required before proceeding to his/her next task. The recorded data with time-date of each event will be transferred to a central computer for statistical analysis and presentation as a daily and/or periodic hand hygiene compliance report on each staff, department, shift and the entire institution.

Priority: US20080063496P Applic. Date: 2008-02-04; US20080063497P Applic. Date: 2008-02-04; US20080072261P Applic. Date: 2008-03-31; US20080071433P Applic. Date: 2008-04-29

Inventor: HUANG CHING CHING [US]; PENG JENNIFER [US]; HWANG FRANCINE N [US]


Application No.: US20090196535A1  Published: 06/Aug/2009

Title: BAG WITH IMPROVED FEATURES

Applicant/Assignee:

Application No.: 12/304832   Filing Date: 29/Jun/2007

Abstract:

The bag for receiving refuse may include a bag body, the bag body including an inside surface, an outside surface, and a rim defining a mouth. The bag may also include a first strip of material disposed on the inside surface of the bag body proximate the rim. The strip may include an inside surface, an outside surface that faces the inside surface of the body, a top edge, and a bottom edge. The bag may also include a front wall, a back wall, and a hem, the hem including a drawstring. The strip may include a printed design. The design could be letters, numbers, pictures, writing, or any other design. When the bag is inserted into a trash receptacle such that the rim of the bag is folded over the rim of the receptacle, the printed design is visible from outside the receptacle.

Priority: US20060831155P Applic. Date: 2006-07-14; WO2007US72460 Applic. Date: 2007-06-29

Inventor: DORSEY ROBERT T [US]; FRASER ROBERT W [US]; MACK-ROBLES NANCY M [US]; BROERING SHAUN T [US]; TOERNER KARIN L [US]


Application No.: US20090196794A1  Published: 06/Aug/2009

Title: APPARATUS AND METHOD FOR RAPID HEAT TRANSFER STERILIZATION

Applicant/Assignee:

Application No.: 12/024483   Filing Date: 01/Feb/2008

Abstract:

A device and method is disclosed for sterilizing objects, commonly dental, medical, or veterinary instruments. By subjecting the objects to heat, the objects are sterilized quickly and more conveniently. The invention allows for user controls and treatment cycles to suit the needs of the sterilizing industry.

Priority:

Inventor: SMITH WILLIAM [US]; SLAVIK NELSON [US]


Application No.: US20090196834A1  Published: 06/Aug/2009

Title: Tobacco alkaloid releasing chewing gum

Applicant/Assignee:

Application No.: 11/631056   Filing Date: 29/Jun/2005

Abstract:

The invention relates to a tobacco alkaloid releasing chewing gum comprising tobacco alkaloid, gum base, and chewing gum ingredients, said gum base comprising elastomer and resin-compounds constituting an amount in the range of about 2 to 20% by weight of said chewing gum.

Priority: DK20040001022 Applic. Date: 2004-06-29; WO2005DK00442 Applic. Date: 2005-06-29

Inventor: ANDERSEN CARSTEN [DK]


Application No.: US20090196844A1  Published: 06/Aug/2009

Title: COMPOSITION FOR INHIBITING ADHESION

Applicant/Assignee: SAMYANG CORPORATION

Application No.: 12/162497   Filing Date: 01/Feb/2007

Abstract:

There is provided in the present invention a composition for inhibiting adhesion comprising polymers that are dissolved in an aqueous solution and have temperature sensitivity showing a sol-gel phase transition dependant upon temperature, wherein the polymer solution in a sol state becomes a gel state by body temperature and is thus stably coated within tissues whereby it functions as a membrane inhibiting adhesion and as time lapses, it is degraded into low molecular weight surfactants and bio-degradable single molecular substances whereby they can be absorbed into body and the degraded products can bring about secondary adhesion inhibiting effects.

Priority: KR20060009849 Applic. Date: 2006-02-01; WO2007KR00543 Applic. Date: 2007-02-01

Inventor: CHOI IN-JA [KR]; SEO MIN-HYO [KR]; KIM BONG-OH [KR]; SHIM MYUNG-SEOB [KR]


Application No.: US20090196872A1  Published: 06/Aug/2009

Title: HUMAN MONOCLONAL ANTIBODIES TO INFLUENZA M2 PROTEIN AND METHODS OF MAKING AND USING SAME

Applicant/Assignee: KIRIN BEER KABUSHIKI KAISHA

Application No.: 11/577695   Filing Date: 05/Dec/2005

Abstract:

Human, humanized and chimeric monoclonal antibodies that bind to influenza M2 protein. A human monoclonal antibody that binds to influenza M2 protein having different amino acid sequences. The antibodies are useful for, among other things, treatment, diagnostics, purifying and isolating M2 or influenza virus, and identifying the presence of M2 or influenza virus in a sample or a subject.

Priority: US20040633846P Applic. Date: 2004-12-06; US20050724198P Applic. Date: 2005-10-06; WO2005IB04146 Applic. Date: 2005-12-05

Inventor: KATO SHINICHIRO [JP]; WANG RONGFANG [CN]


Application No.: US20090196912A1  Published: 06/Aug/2009

Title: Pyridinylamines

Applicant/Assignee: GPC BOTECH AG

Application No.: 11/659013   Filing Date: 01/Aug/2005

Abstract:

Described are pyridinylamines and pharmaceutically acceptable salts thereof, the use of these pyridinylamines for the prophylaxis and/or treatment of various diseases such as infectious diseases, including opportunistic infections, prion diseases immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, as well as pharmaceutical compositions containing at least one pyridinylamine and/or pharmaceutically acceptable salts thereof. Furthermore, reaction procedures for the synthesis of the pyridinylamines are disclosed.

Priority: EP20040018131 Applic. Date: 2004-07-30; US20040599307P Applic. Date: 2004-08-06; WO2005EP08321 Applic. Date: 2005-08-01

Inventor: EICKHOFF JAN ELKE [DE]; HAFENBRADL DORIS [DE]; SCHWAB WILFRIED [DE]; COTTON MATTHEW [GM]; KIEBL BERT MATTHIAS [DE]; ZECH BIRGIT [DE]; MULLER STEFAN [DE]; HARRIS JOHN [GB]; SAVIC VLADIMIR [SA]; MACRITCHIE JACKIE [GB]


Application No.: US20090197219A1  Published: 06/Aug/2009

Title: SYSTEM FOR A DENTAL IMPLANT SURGICAL GUIDE

Applicant/Assignee:

Application No.: 12/375330   Filing Date: 30/Jul/2007

Abstract:

The invention concerns guided dental implant surgery involving the preparation of a model with balls indicatine the emergent point of each implant, the preparation of a radiological plate starting from the model and equipped with a radiopaque ball placed in the cast corresponding to each ball of said model, the application of a reference fork for the radiological claque for the carrying out of a CAT scan, the elaboration of the CAT scan data with reference to the emergent point of the implant and successive preparation of a surgical guide with fixing of a directional sleeve on the plaque starting from the emergent point.

Priority: IT2006BS00169 Applic. Date: 2006-08-02; WO2007IT00543 Applic. Date: 2007-07-30

Inventor: RIZZO ROSARIO [IT]


Application No.: US20090197221A1  Published: 06/Aug/2009

Title: DENTAL BONDING COMPOSITIONS AND METHODS USEFUL IN INHIBITION OF MICROLEAKAGE IN RESIN-BONDED DENTIN

Applicant/Assignee:

Application No.: 12/025668   Filing Date: 04/Feb/2008

Abstract:

Provided are methods and compositions relating to a dental bonding composition useful in bonding a dental resin composite.

Priority:

Inventor: MARSHALL JR GRAYSON W [US]; MARSHALL SALLY J [US]; ZEIGER DIANA N [US]; TOMSIA ANTONI P [US]; SAIZ EDUARDO [US]


Application No.: US20090197967A1  Published: 06/Aug/2009

Title: COMPOSITIONS AND METHODS FOR TREATMENT OF OPHTHALMIC DISEASES AND DISORDERS

Applicant/Assignee:

Application No.: 12/162476   Filing Date: 26/Jan/2007

Abstract:

Provided herein are compositions and methods for treating ophthalmic diseases and disorders. Compositions comprising retinylamine derivative compounds provided herein are useful for treating and preventing ophthalmic diseases and disorders, including diabetic retinopathy diabetic maculopathy, diabetic macular edema, retinal ischemia, ischemia-reperfusion related retinal injury, and metabolic optic neuropathy.

Priority: US20060762384P Applic. Date: 2006-01-26; WO2007US02330 Applic. Date: 2007-01-26

Inventor: KUBOTA RYO [US]; FAWZI AHMAD [US]; SCOTT IAN L [US]; KUKSA VLADIMIR A [US]


Application No.: US20090197987A1  Published: 06/Aug/2009

Title: Sulphonium Salt Initiators

Applicant/Assignee:

Application No.: 12/226116   Filing Date: 04/Apr/2007

Abstract:

Compounds of the formula (I), L, L', L'', L1, L'1, L''1, L2, L'2, L''2, L3, L'3, L''3, L4, L'4, L''4, L5, L'5, L''5, L6, L'6, L''6, L7, L'7, L''7, L8, L'8 and L''8 independently of one another are hydrogen or an organic substituent

and/or one or more of the pairs L3 and L5, L'3 and L'5 or L''3 and L''5 together denote a single bond, provided that the respective X, X' or X'' is not a single bond

and/or L3 and L5, L'3 and L'5 or L''3 and L''5 together denote an organic linking group

and/or one or more of the pairs L1 and L3, L1 and L, L5 and L7, L'1 and L'3, L'1 and L', L'5 and L'7, L''1 and L''3, L''1 and L'', or L''5 and L''7, together denote an organic linking group

provided that at least one of L, L', L'', L1, L'1, L''1, L2, L'2, L''2, L3, L'3, L''3, L4, L'4, L''4, L5, L'5, L''5, L6, L'6, L''6, L7, L'7, L''7, L8, L'8 and L''8 is other

than hydrogen

X, X' and X'' independently of one another are a single bond, CRaRb O, S, NRc or NCORc

Ra, Rb and Rc independently of one another are hydrogen or an organic substituent

and Y is an inorganic or organic anion

are suitable as photolatent acid generators.

Priority: EP20060112602 Applic. Date: 2006-04-13; WO2007EP53280 Applic. Date: 2007-04-04

Inventor: HAYOZ PASCAL [CH]; ILG STEPHAN [CH]


Application No.: US20090198262A1  Published: 06/Aug/2009

Title: DISPOSABLE TONGUE SCRAPER

Applicant/Assignee: DISCUS DENTAL, LLC

Application No.: 11/963510   Filing Date: 21/Dec/2007

Abstract:

The present invention relates to a dental implement such as tongue scraper that is disposable and is adapted for prophylactic and/or therapeutic action for the oral cavity. The dental implement may include a tongue scraper, a dental floss, a toothpick, a toothbrush or combinations thereof. The dental implement may include a strip having a longitudinal dimension that is longer than its traverse dimension. The strip may be coated with a coating of a mixture including at least one medicament and a water soluble or erodible carrier. In one embodiment, the coating may be present on at least one of the longitudinal edges, for example, of a tongue scraper, toothpick or a dental floss. In another embodiment, the coating may be present on at least one of the traverse edges, for example, of a tooth pick or the bristles of a toothbrush. In a further embodiment, the coating may be present on a combination of edges. The integrity of the implement, such as a scraper and/or its edge or edges may be reinforced by the coating of substance or agent for sufficient integrity, and the scraper or its edge and/or the coating, for example, are adapted to degrade or break down as the substance or agent are released during use and/or upon contact with water and/or saliva. The dental implement may be exposed for use, and is appropriately stored prior to use.

Priority: US20060877345P Applic. Date: 2006-12-26; US20060877337P Applic. Date: 2006-12-26

Inventor: ROSENBLOOD KENNETH [US]; QUAN CHRISTOPHER [US]; MEJIA SCOTT [US]; MCLOUGHLIN BRENDAN [US]


Application No.: US20090198345A1  Published: 06/Aug/2009

Title: CALCIUM SILICATE-BASED COMPOSITE CEMENT AND MANUFACTURING METHOD THEREOF

Applicant/Assignee: CHUNG SHAN MEDICAL UNIVERSITY

Application No.: 12/025701   Filing Date: 04/Feb/2008

Abstract:

The present invention provides a method for producing calcium silicate-based bone cement and a composition produced by the method. It further provides a novel mixture for bone tissue repair.

Priority:

Inventor: DING SHINN-JYH [TW]


Application No.: US20090199429A1  Published: 13/Aug/2009

Title: DEVICES WITH INTERNAL FLEXIBILITY SIPES, INCLUDING SIPED CHAMBERS FOR FOOTWEAR

Applicant/Assignee:

Application No.: 11/719637   Filing Date: 21/Nov/2005

Abstract:

The present invention attempts to replicate in footwear, orthotics, and other products the naturally effective anatomical structures like a bare foot that provide superior flexibility, cushioning, and stable support compared to existing products. More specifically, the invention relates to a device for such products including a unitary internal sipe component, said internal sipe providing increased flexibility for said device. Even more specifically, the invention relates to footwear, orthotic or other products with an outer chamber and at least one inner chamber inside the outer chamber

the outer chamber and the inner chamber being separated at least in part by an internal sips

and the internal sipe providing increased flexibility, cushioning, and stability.

Priority: US20040629384P Applic. Date: 2004-11-22; US20040629385P Applic. Date: 2004-11-22; US20040629523P Applic. Date: 2004-11-22; US20040633664P Applic. Date: 2004-12-06; US20040634781P Applic. Date: 2004-12-09; US20040634782P Applic. Date: 2004-12-09; US20050672407P Applic. Date: 2005-04-18; US20050677538P Applic. Date: 2005-05-04; US20050679182P Applic. Date: 2005-05-09; US20050700179P Applic. Date: 2005-07-18; WO2005US42341 Applic. Date: 2005-11-21

Inventor: ELLIS FRAMPTON E [US]


Application No.: US20090202449A1  Published: 13/Aug/2009

Title: USE OF OSTEOPONTIN IN DENTAL FORMULATIONS

Applicant/Assignee: ARLA FOODS AMBA

Application No.: 12/363661   Filing Date: 30/Jan/2009

Abstract:

Use of osteopontin for reducing plaque bacterial growth on tooth enamel and dental formulations containing osteopontin.

Priority: DK20030001777 Applic. Date: 2003-12-01; US2004-000028 Applic. Date: 2004-12-01; US20030525828P Applic. Date: 2003-12-01

Inventor: BURLING HANS [SE]; SORENSEN ESBEN SKIPPER [DK]; BERTELSEN HANS [DK]; JORGENSEN ANDERS STEEN [DK]; GRAVERHOLT GITTE [DK]


Application No.: US20090202450A1  Published: 13/Aug/2009

Title: ORAL CARE PRODUCT AND METHODS OF USE AND MANUFACTURE THEREOF

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/058278   Filing Date: 28/Mar/2008

Abstract:

This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an anionic surfactant, and to methods of using and of making such compositions.

Priority: US20080027431P Applic. Date: 2008-02-08; US20080027420P Applic. Date: 2008-02-08; US20080027432P Applic. Date: 2008-02-08

Inventor: PRENCIPE MICHAEL [US]; CUMMINS DIANE [US]; SUBRAMANAYAM RAVI [US]; SULLIVAN RICHARD J [US]; SANTARPIA III RALPH PETER [US]; MELLO SARITA V [US]; ZAIDEL LYNETTE [US]; CHOPRA SUMAN [US]; WANG QIN [US]; TAMBS GARY EDWARD [US]; BARNES VIRGINIA MONSUL [US]; WU DONGHUI [US]; MORGAN ANDRE M [US]; KOHLI RAJNISH [US]; ROBINSON RICHARD SCOTT [US]; LEITE SERGIO [US]; SIMON ERIC A [US]


Application No.: US20090202451A1  Published: 13/Aug/2009

Title: ORAL CARE PRODUCT AND METHODS OF USE AND MANUFACTURE THEREOF

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/058424   Filing Date: 28/Mar/2008

Abstract:

This invention relates to oral care compositions comprising a basic amino acid or salt thereof, and a small particle fraction: and to methods of using and of making these compositions.

Priority: US20080027431P Applic. Date: 2008-02-08; US20080027420P Applic. Date: 2008-02-08; US20080027435P Applic. Date: 2008-02-08; US20080027432P Applic. Date: 2008-02-08

Inventor: PRENCIPE MICHAEL [US]; CUMMINS DIANE [US]; ROBINSON RICHARD SCOTT [US]; MELLO SARITA V [US]; SULLIVAN RICHARD J [US]; CHOPRA SUMAN [US]; DEPIERRO KAREN J [US]; ZAIDEL LYNETTE [US]; CHRISTOPOULOU CONSTANTINA [US]; SUBRAMANYAM RAVI [US]; WU DONGHUI [US]; MORGAN ANDRE M [US]; SANTARPIA III RALPH PETER [US]; WANG QIN [US]; TAMBS GARY EDWARD [US]; KOHLI RAJNISH [US]; BARNES VIRGINIA MONSUL [US]; LEITE SERGIO [US]; SIMON ERIC A [US]


Application No.: US20090202453A1  Published: 13/Aug/2009

Title: Oral Composition

Applicant/Assignee: HINDUSTAN LEVER LIMITED

Application No.: 11/658958   Filing Date: 13/Jul/2005

Abstract:

An opaque toothpaste composition and method for making such, the toothpaste comprising water, a zinc salt, a chelating agent for the zinc salt, the chelating agent having a log Ks1 as herein defined of from 3.0 to 7.0, and an abrasive present at from 10% to 70% by weight of the composition, said abrasive comprising calcium carbonate.

Priority: EP20040254661 Applic. Date: 2004-08-03; EP20040254662 Applic. Date: 2004-08-03; EP20040257063 Applic. Date: 2004-11-15; EP20040257064 Applic. Date: 2004-11-15; EP20050250131 Applic. Date: 2005-01-13; EP20050250642 Applic. Date: 2005-01-26; WO2005EP07718 Applic. Date: 2005-07-13

Inventor: WATERFIELD PHILIP CHRISTOPHER [GB]


Application No.: US20090202454A1  Published: 13/Aug/2009

Title: ORAL CARE PRODUCT AND METHODS OF USE AND MANUFACTURE THEREOF

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/058209   Filing Date: 28/Mar/2008

Abstract:

This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an antibacterial agent, and to methods of using and of making such compositions.

Priority: US20080027431P Applic. Date: 2008-02-08; US20080027432P Applic. Date: 2008-02-08; US20080027420P Applic. Date: 2008-02-08

Inventor: PRENCIPE MICHAEL [US]; SUBRAMANYAM RAVI [US]; MELLO SARITA V [US]; WU DONGHUI [US]; CHOPRA SUMAN [US]; MORGAN ANDRE M [US]; CUMMINS DIANE [US]; SULLIVAN RICHARD J [US]; SANTARPIA III RALPH PETER [US]; ZAIDEL LYNETTE [US]; WANG QIN [US]; TAMBS GARY EDWARD [US]; BARNES VIRGINIA MONSUL [US]; KOHLI RAJNISH [US]; ROBINSON RICHARD SCOTT [US]; LEITE SERGIO [US]; SIMON ERIC A [US]


Application No.: US20090202455A1  Published: 13/Aug/2009

Title: ORAL CARE PRODUCT AND METHODS OF USE AND MANUFACTURE THEREOF

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/058360   Filing Date: 28/Mar/2008

Abstract:

This invention relates to oral care compositions comprising an effective amount of a salt of a basic amino acid the salt having a pH in an unbuffered solution of less than about 7.5

an effective amount of a soluble fluoride salt

and a particulate material which has a pH in an unbuffered solution of less than about 7.5

and to methods of using and of making such compositions.

Priority: US20080027431P Applic. Date: 2008-02-08; US20080027420P Applic. Date: 2008-02-08; US20080027432P Applic. Date: 2008-02-08

Inventor: KOHLI RAJNISH [US]; ROBINSON RICHARD SCOTT [US]; LEITE SERGIO [US]; SIMON ERIC A [US]; SULLIVAN RICHARD J [US]; SANTARPIA III RALPH PETER [US]; PRENCIPE MICHAEL [US]; SUBRAMANYAM RAVI [US]; MELLO SARITA V [US]; WU DONGHUI [US]; CHOPRA SUMAN [US]; MORGAN ANDRE M [US]; CUMMINS DIANE [US]; ZAIDEL LYNETTE [US]; WANG QIN [US]; TAMBS GARY EDWARD [US]; BARNES VIRGINIA MONSUL [US]


Application No.: US20090202456A1  Published: 13/Aug/2009

Title: NOVEL SALTS AND THEIR USES

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/058387   Filing Date: 28/Mar/2008

Abstract:

The invention relates to novel arginine salts, compositions comprising them, and their uses.

Priority: US20080027442P Applic. Date: 2008-02-09; US20080027432P Applic. Date: 2008-02-08; US20080027431P Applic. Date: 2008-02-08; US20080027420P Applic. Date: 2008-02-08

Inventor: PRENCIPE MICHAEL [US]; XU GUOFENG [US]; SUBRAMANYAM RAVI [US]; WU DONGHUI [US]; CUMMINS DIANE [US]; SULLIVAN RICHARD J [US]; SANTARPIA III RALPH PETER [US]; MELLO SARITA V [US]; ZAIDEL LYNETTE [US]; CHOPRA SUMAN [US]; WANG QIN [US]; TAMBS GARY EDWARD [US]; BARNES VIRGINIA MONSUL [US]; MORGAN ANDRE M [US]; KOHLI RAJNISH [US]; ROBINSON RICHARD SCOTT [US]; LEITE SERGIO [US]; SIMON ERIC A [US]


Application No.: US20090202588A1  Published: 13/Aug/2009

Title: Nucleic acids encoding TGEV and PRRSV sequences for improved expression of PRRSV sequences

Applicant/Assignee:

Application No.: 11/606237   Filing Date: 30/Nov/2006

Abstract:

The present invention relates to nucleic acids comprising: (a) sequences of a replication competent transmissible gastroenteritis virus (TGEV), which sequences encode a TGEV replicase under the control of expression regulatory sequences, wherein the replicase is expressed in a host cell and will initiate replication of the nucleic acid and thus increase the number of nucleic acids in the cell

and (b) a sequence encoding at least one neutralizing epitope of ORF5 of porcine reproductive and respiratory syndrome virus (PRRSV), which sequence includes a disulfide bridge forming residue

and (c) a sequence encoding at least one further polypeptide capable of increasing an immune response against PRRSV. The present invention further relates to vectors, virus particles and host cells comprising these nucleic acids as well as their use for the preparation of vaccines, specifically for the preparation of vaccines.

Priority: EP20050026255 Applic. Date: 2005-12-01

Inventor: ENJUANES SANCHES LUIS [ES]; ZUNIGA LUCAS SONIA [ES]; SOLA GURPEGUI ISABEL [ES]; PLANA DURAN JOAN [ES]


Application No.: US20090202622A1  Published: 13/Aug/2009

Title: VIROSOME-LIKE VESICLES COMPRISING GP41-DERIVED ANTIGENS

Applicant/Assignee: MYMETICS CORPORATION INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (INSERM) PEVION BIOTECH LTD

Application No.: 12/281256   Filing Date: 02/Mar/2007

Abstract:

The present invention relates to a virosome-like vesicle comprising at least a gp41-derived antigen or an analogue thereof, said gp41-derived antigen being located to the external surface of and/or encapsulated inside said vesicle and being in a convenient configuration for conferring said virosome-like vesicle with an ability to induce an immune response against a gp41 protein or a human immunodeficiency virus (HIV).

Priority: WO2006IB00466 Applic. Date: 2006-03-03; WO2007IB00502 Applic. Date: 2007-03-02

Inventor: FLEURY SYLVAIN [CH]; BOMSEL MORGANE [FR]; ZURBRIGGEN RINALDO [CH]


Application No.: US20090203606A1  Published: 13/Aug/2009

Title: Systems for and Methods of use of Therapeutic Nutrition for the Management of Age-Associated and Age-Specific Health Conditions of the Elderly

Applicant/Assignee:

Application No.: 12/366520   Filing Date: 05/Feb/2009

Abstract:

Nutritional compositions which provide for improved taste profiles for the elderly while simultaneously providing nutrition specific to assist in the management of nutritional deficiencies that lead to age specific and age associated health conditions in the elderly. There are also provided products using these compositions and incorporating packaging design, volume delivery, and sensory attributes to improve nutritional regimen compliance in the elderly.

Priority: US20080026302P Applic. Date: 2008-02-05

Inventor: WOLFE ROBERT R [US]; TROUP JOHN P [US]; DEUTZ NICOLAAS E P [US]


Application No.: US20090203618A1  Published: 13/Aug/2009

Title: Analog compounds of analgesic peptides derived from the venom of crotalus durissus terrificus snakes, their uses, compositions, methods of preparation and purification

Applicant/Assignee:

Application No.: 11/579615   Filing Date: 06/May/2005

Abstract:

The present invention refers to analog compounds of peptides having the amino acid sequences SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3 or SEQ ID NO: 4, including analgesic peptides derived from snakes of species such as Crotalus durissus terrificus

their uses in the treatment, diagnosis and prevention of painful conditions or mediated by opioid receptors, their pharmaceutical compositions and their methods of preparation and purification, including their uses in the identification of analgesic compounds.

Priority: BR2004PI01702 Applic. Date: 2004-05-06; BR20020005002 Applic. Date: 2005-05-02; WO2005BR00073 Applic. Date: 2005-05-06

Inventor: CURY YARA [BR]; PICOLO GISELE [BR]; KONNO KATSUHIRO [BR]; GIORGI RENATA [BR]; BRIGATTE PATRICIA [BR]; GUTIERREZ VANESSA [BR]; CAMARGO ANTONIO [BR]


Application No.: US20090203662A1  Published: 13/Aug/2009

Title: NOVEL DERIVATIVES OF CHOLEST-4-EN-3-ONE OXIME, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PREPARATION METHOD

Applicant/Assignee: TROPHOS

Application No.: 12/158640   Filing Date: 15/Dec/2006

Abstract:

The object of the invention is the use as a drug of a compound fitting formula I wherein X represents an oxygen atom or a -N-OH group and R represents a group selected from or one of its esters and/or of its addition salts with pharmaceutically acceptable acids, particularly as a cytoprotective drug, preferentially a cardioprotective and/or neuroprotective drug, the compounds of formula I wherein R is R2, R3, R4, R5 or R6 as novel compounds as well as their preparation method and use.

Priority: FR20050012947 Applic. Date: 2005-12-20; WO2006FR02740 Applic. Date: 2006-12-15

Inventor: DROUOT CYRILLE [FR]; MAUX DELPHINE [FR]


Application No.: US20090203702A1  Published: 13/Aug/2009

Title: INHIBITORS OF p38

Applicant/Assignee: VERTEX PHARMACEUTICALS INCORPORATED

Application No.: 12/062495   Filing Date: 03/Apr/2008

Abstract:

The present invention relates to inhibitors of p38, a mammalian protein kinase involved cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.

Priority: US2005-298324 Applic. Date: 2005-12-08; US2003-622320 Applic. Date: 2003-07-17; US1999-336266 Applic. Date: 1999-06-18; WO1997US23392 Applic. Date: 1997-12-17; US1997-862925 Applic. Date: 1997-06-10; US1997-822373 Applic. Date: 1997-03-20; US19960034288P Applic. Date: 1996-12-18

Inventor: BEMIS GUY W [US]; SALITURO FRANCESCO GERALD [US]; DUFFY JOHN PATRICK [US]; COCHRAN JOHN E [US]; HARRINGTON EDMUND MARTIN [US]; MURCKO MARK A [US]; WILSON KEITH P [US]; SU MICHAEL [US]; GALULLO VINCENT P [US]


Application No.: US20090203752A1  Published: 13/Aug/2009

Title: COMPOUNDS FOR NONSENSE SUPPRESSION, AND METHODS FOR THEIR USE

Applicant/Assignee: PTC THERAPEUTICS, INC

Application No.: 11/577192   Filing Date: 13/Oct/2005

Abstract:

The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.

Priority: US20040617634P Applic. Date: 2004-10-13; US20040617633P Applic. Date: 2004-10-13; US20040617653P Applic. Date: 2004-10-13; US20040617655P Applic. Date: 2004-10-13; US20040617670P Applic. Date: 2004-10-13; US20040624170P Applic. Date: 2004-11-03; WO2005US37052 Applic. Date: 2005-10-13

Inventor: CAMPBELL JEFFREY A [US]; KAHN ATIYYA [US]; TAKASUGI JAMES [US]; WELCH ELLEN [US]


Application No.: US20090204105A1  Published: 13/Aug/2009

Title: COUPLING DEVICE FOR MEDICAL PURPOSES AND AN ACCESS SYSTEM INCLUDING SUCH A COUPLING DEVICE

Applicant/Assignee: GAMBRO CREDIT AB

Application No.: 12/161138   Filing Date: 29/Nov/2006

Abstract:

A coupling device (3,4) for medical purposes with at least one coupling channel (9,18) having a mouth in a coupling surface (10), for sealed co-operation with at least one access channel (7) with a mouth in a connecting surface (beta). of an access device (2), which is connectable to a patient, is distinguished in that the coupling surface (10) includes a flexible portion (11) for contacting against the connecting surface (6) and being of a material having a higher degree of flex than a primary material of the coupling device, which portion for sealing purposes surrounds the mouth of said at least one coupling channel (9,18).

Priority: SE20060000079 Applic. Date: 2006-01-17; WO2006SE01363 Applic. Date: 2006-11-29

Inventor: JOHANSSON ROGER [SE]; PERSSON DICK [SE]


Application No.: US20090205293A1  Published: 20/Aug/2009

Title: FILLING MACHINE FOR OPEN, SEALABLE SACKS

Applicant/Assignee: HAVER & BOECKER OHG

Application No.: 12/300228   Filing Date: 07/Mar/2007

Abstract:

A filling machine for open, sealable sacks includes a fill pipe for filling the attached sacks with contents having a tendency to develop dust, and a cleaning device which includes a blow rail for cleaning the inner faces of the sack mouth rim and side folds of a sack by an air flow which emerges from the blow rail. The blow rail is fastened to two-armed levers which can be pivoted about a stationary axis by means of a drive. As a result, the air jets are directed onto the surfaces to be cleaned from different directions during the cleaning process and the layers of the side folds are also separated from one another and cleaned. The filling machine is suitable, in particular, for filling powdery contents.

Priority: DE200610021850 Applic. Date: 2006-05-09; WO2007EP52121 Applic. Date: 2007-03-07

Inventor: COMBRINK ALOIS [DE]; BERGEREM JOSEF VAN [DE]


Application No.: US20090208426A1  Published: 20/Aug/2009

Title: Use of Diacetyl Trimer as an Aromatic and Flavouring Substance

Applicant/Assignee: SYMRISE GMBH & CO. KG

Application No.: 11/720582   Filing Date: 30/Nov/2005

Abstract:

The invention relates to the use of 2,5-diacetyl-3a,5,6,6a-tetrahydro-6a-hydroxy-2,3a,5-trimethylfuro[2,3-d]-1,3-dioxole (diacetyl trimer) of the formula in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two or more of the stereoisomers (i) as an odoriferous or aromatic substance, (ii) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (iii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavour, and/or (iv) for masking a bitter flavour. The invention furthermore relates to corresponding aromatic compositions as well as compositions which serve for nutrition, oral hygiene, consumption for pleasure or for oral pharmaceutical use.

Priority: US20040633194P Applic. Date: 2004-12-03; WO2005EP56355 Applic. Date: 2005-11-30

Inventor: GATFIELD IAN [DE]; LEY JAKOB [DE]; REISS INGO [DE]; KINDEL GUENTER [DE]; KRAMMER GERHARD [DE]


Application No.: US20090208428A1  Published: 20/Aug/2009

Title: Bioactive Glass

Applicant/Assignee: IMPERIAL INNOVATIONS LIMITED

Application No.: 12/304790   Filing Date: 15/Jun/2007

Abstract:

The present invention relates to a bioactive glass comprising strontium and silicon dioxide, processes for the production of the bioactive glass and the use of the bioactive glass in medicine.

Priority: GB20060012028 Applic. Date: 2006-06-16; WO2007GB02262 Applic. Date: 2007-06-15

Inventor: HILL ROBERT GRAHAM [GB]; STEVENS MOLLY MORAG [GB]


Application No.: US20090208473A1  Published: 20/Aug/2009

Title: COMPOSITIONS AND METHODS TO MODULATE CELL MEMBRANE RESEALING

Applicant/Assignee:

Application No.: 12/328646   Filing Date: 04/Dec/2008

Abstract:

Disclosed herein are compositions and methods for repairing cell membranes. In addition, the invention relates to therapeutic compositions comprising nucleotides and/or polypeptides of the invention in combination with a pharmaceutically acceptable carrier, wherein the composition facilitates the repair of cell membranes. Moreover, the invention relates to the treatment and/or prevention of pathological conditions associated with cell membrane damage.

Priority: US20070005410P Applic. Date: 2007-12-04

Inventor: WEISLEDER NOAH [US]; CAI CHUANXI [US]; MA JIANJIE [US]


Application No.: US20090208493A1  Published: 20/Aug/2009

Title: Compounds and methods for the selective inhibition of ABCB1, ABCC1 and ABCG2 transporters and the treatment of cancers, especially drug resistant cancers and high throughput flow cytometry assay to detect selective inhibitors

Applicant/Assignee: STC. UNM

Application No.: 12/315132   Filing Date: 28/Nov/2008

Abstract:

Compounds disclosed which inhibit ABCB1 transporter protein are useful for treating diseases in which ABCB1 transporter protein mediates the disease state, including numerous cancers, including hematopoietic cancers, including various leukemias, especially T-lineage acute lymphoblastic leukemia, as well as cancerous tumors, especially forms which exhibit multiple drug resistance. Pharmaceutical compositions which comprise an inhibitor of ABCB1 transporter protein and at least one additional anticancer agent, optionally in combination with a pharmaceutically acceptable carrier, additive or excipient are another aspect of the present invention. A flow cytometry based, high-throughput screening (HST) assay that quantifies ABCB1 efflux is also disclosed. Methods of identifying inhibitors of ABCB1, ABCG2 and ABCC1 transporter proteins are also disclosed.

Priority: US20070004342P Applic. Date: 2007-11-27; US20080124377P Applic. Date: 2008-04-16; US20080131214P Applic. Date: 2008-06-06

Inventor: LARSON RICHARD S [US]; SKLAR LARRY A [US]; EDWARDS BRUCE S [US]; IVNITSKI-STEELE IRENA D [US]; OPREA TUDOR I [US]; LOVATO DEBBIE M [US]; KHAWAJA HADYA M [US]; WINTER STUART S [US]; YOUNG SUSAN M [US]


Application No.: US20090208543A1  Published: 20/Aug/2009

Title: METHOD AND APPARATUS FOR APPLYING A PROTECTIVE ORAL CARE COMPOSITION

Applicant/Assignee: ORAL HEALTH CLINICAL SERVICES

Application No.: 12/357924   Filing Date: 22/Jan/2009

Abstract:

Compositions and methods for whitening human teeth containing peroxide and a hydroperoxidase inhibitor. The compositions exhibit superior teeth whitening effects while also retaining a greater amount of peroxide compared to compositions not containing the hydroperoxidase inhibitors. The compositions may be formulated in a hydrocarbon humectant free vehicle comprising a peroxide compound, a hydroperoxidase inhibitor, a chelating agent, an anti-oxidizing agent, and a thickening agent. The compositions may further include compounds to reduce oxidative stress. Also disclosed is a delivery system including a flexible film, an oral care composition that contacts the teeth, an adhesive material that generally contacts the soft tissues, and a physical barrier that prevents contact between the oral care composition and the adhesive material.

Priority: US20080022659P Applic. Date: 2008-01-22

Inventor: NATHOO SALIM A [US]


Application No.: US20090208576A1  Published: 20/Aug/2009

Title: Orally Disintegrating Tablets

Applicant/Assignee:

Application No.: 12/293857   Filing Date: 30/Mar/2007

Abstract:

The present invention describes a directly compressible composite prepared by co-processing a water-soluble excipient and calcium silicate. The present invention further describes the incorporation of the co-processed composite into a tablet formulation. The orally disintegrating tablets are of optimal mechanical strength and disintegrate within 60 seconds in the oral cavity.

Priority: IN2006MU00498 Applic. Date: 2006-03-31; WO2007IN00138 Applic. Date: 2007-03-30

Inventor: GANDHI ANILKUMAR S [IN]; BAGDE PRADNYA [IN]; MORVEKAR HETAL N [IN]; PILGAONKAR PRATIBHA S [US]; RUSTOMJEE MAHARUKH T [IN]


Application No.: US20090208872A1  Published: 20/Aug/2009

Title: Sulphonium Salt Initiators

Applicant/Assignee:

Application No.: 11/922444   Filing Date: 21/Jun/2006

Abstract:

Compounds of the formula (I), (II), (III), (IV) and wherein, R is hydrogen, C1-C20alkyl

C2-C20alkyl interrupted by one or more O

is -L-X-R2 or -L-R2

R1 has for example one of the meanings as given for R

R2 is a monovalent sensitizer or photoinitiator moiety

Ar1 and Ar2 for example independently of one another are phenyl substituted by C1-C20alkyl, halogen or OR3

or are unsubstituted naphthyl, anthryl, phenanthryl or biphenylyl

or are naphthyl, anthryl, phenanthryl or biphenylyl substituted by C1-C20alkyl, OH or OR3

or are -Ar4-A-Ar3

Ar3 is unsubstituted phenyl naphthyl, anthryl, phenanthryl or biphenylyl

or is phenyl, naphthyl, anthryl, phenanthryl or biphenylyl substituted by C1-C20alkyl, OR3 or benzoyl

Ar4 is phenylene, naphthylene, anthrylene or phenanthrylene

A is a direct bond, S, O or C1-C20alkylene

X is CO, C(O)O, OC(O), O, S or NR3

L is C1-C20alkylene or C2-C20alkylene interrupted by one or more O

R3 is C1-C20alkyl or C1-C20hydroxyalkyl

and Y is an anion, are suitable as photolatent acid generators.

Priority: EP20050105991 Applic. Date: 2005-07-01; WO2006EP63378 Applic. Date: 2006-06-21

Inventor: WOLF JEAN-PIERRE [CH]; LATIKA ATTILA [SK]; BIRBAUM JEAN-LUC [CH]; ILG STEPHAN [CH]; HAYOZ PASCAL [CH]


Application No.: US20090208896A1  Published: 20/Aug/2009

Title: Methods and Devices for Diastema Closure

Applicant/Assignee:

Application No.: 12/267539   Filing Date: 07/Nov/2008

Abstract:

In a method for closing a diastema and/or papilla regeneration between a first tooth and a second tooth, a dental matrix is used. The dental matrix includes a curved sectional strip of material. The strip has a length from a first end to a second end sufficient to create a form for molding a restorative material to a surface of the first tooth. The strip has a root end section and a second section integral with the root end section. The root end section of the strip is anatomic in shape such that the root end section hugs the gingival portion of the first tooth. In one form, a non-anatomic bulge is formed in the second section. The root end section of the matrix can slide to the depth of the sulcus without lacerating the tissue. After inserting the root end section of the dental matrix into the sulcus between the papilla and the gingival portion of the first tooth, a composite restorative material is placed between the dental matrix and a cervical surface of the first tooth. The composite restorative material is then cured. This creates bulbousness in the cured composite near the gum line to fill the gingival gapping.

Priority: US20070986244P Applic. Date: 2007-11-07

Inventor: CLARK DAVID J [US]


Application No.: US20090208904A1  Published: 20/Aug/2009

Title: Dental implant

Applicant/Assignee:

Application No.: 12/070112   Filing Date: 19/Feb/2008

Abstract:

A dental implant is described, which has an internal axial force absorbing the dissipating member encased within resilient material so as to suspend a prosthetic supporting section.

Priority:

Inventor: LANS MARIS J [US]


Application No.: US20090208905A1  Published: 20/Aug/2009

Title: EXPANDABLE DENTAL IMPLANTS OF HIGH SURFACE AREA AND METHODS OF EXPANDING THE SAME

Applicant/Assignee:

Application No.: 12/439500   Filing Date: 22/Aug/2007

Abstract:

A dental implant system for placement within a jaw of a patient includes an envelope including an outer surface and an inner surface defining a barrel. At least one barrier is located in the barrel. The barrel having a first region on one side of the barrier and a second region on an opposing side of the barrier. An expander member is movable within the barrel along a longitudinal axis of the barrel from the first region to the second region. The barrier prohibits the expander member from moving from the second region to the first region.

Priority: IL20060177848 Applic. Date: 2006-09-03; WO2007IB02396 Applic. Date: 2007-08-22

Inventor: VACHTENBERG OZ [IL]


Application No.: US20090208909A1  Published: 20/Aug/2009

Title: DENTAL FILLERS AND COMPOSITIONS INCLUDING PHOSPHATE SALTS

Applicant/Assignee:

Application No.: 11/719469   Filing Date: 07/Nov/2005

Abstract:

The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes a phosphate salt. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment. Dental compositions, and methods of using dental compositions that include a phosphate salt and a hardenable resin or a water-dispersible, polymeric film former are also provided.

Priority: US2004-989780 Applic. Date: 2004-11-16; WO2005US40339 Applic. Date: 2005-11-07

Inventor: RUSIN RICHARD P [US]; MITRA SUMITA B [US]; CUMMINGS KEVIN M [US]


Application No.: US20090209456A1  Published: 20/Aug/2009

Title: COMPOSITIONS AND METHODS FOR IMPROVING FACIAL AND BODY AESTHETICS

Applicant/Assignee:

Application No.: 12/033460   Filing Date: 19/Feb/2008

Abstract:

Compositions and methods of treating facial and body tissue aesthetics and reconstruction are disclosed using immunosuppressive agents either by themselves or in conjunction with other soft tissue fillers.

Priority:

Inventor: SWEIS ILIANA [US]


Application No.: US20090209536A1  Published: 20/Aug/2009

Title: AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE

Applicant/Assignee: KALYPSYS, INC

Application No.: 12/140033   Filing Date: 16/Jun/2008

Abstract:

The present invention relates to compounds and methods useful as modulators of CB2 for the treatment or prevention of disease states including, but not limited to pain, autoimmune disease, malabsorption syndrome, pulmonary disease, osteoporosis, muscle spasm in cancer, neuromuscular disorder, and atherosclerosis progression.

Priority: US20070944510P Applic. Date: 2007-06-17; US20080037347P Applic. Date: 2008-03-18

Inventor: GAHMAN TIMOTHY [US]; THOMAS DAVID [US]; LANG HENGYUAN [US]; MASSARI MARK EBEN [US]


Application No.: US20090209559A1  Published: 20/Aug/2009

Title: PHARMACEUTICAL COMPOUNDS

Applicant/Assignee: F. HOFFMANN-LA ROCHE AG

Application No.: 12/299600   Filing Date: 04/May/2007

Abstract:

Fused pyrimidines of formula (I): wherein A, n, R1, R2, and R3 have any of the values defined herein and the pharmaceutically acceptable salts thereof have activity as inhibitors of PI3K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behavior associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine disorders and neurological disorders. Processes for synthesizing the compounds are also described.

Priority: GB20060008820 Applic. Date: 2006-05-04; WO2007GB01644 Applic. Date: 2007-05-04

Inventor: CHUCKOWREE IRINA S [GB]; FOLKES ADRIAN J [GB]; GOLDSMITH PAUL [GB]; HANCOX TIMOTHY C [GB]; SHUTTLEWORTH STEPHEN J [GB]


Application No.: US20090209607A1  Published: 20/Aug/2009

Title: INHIBITORS OF AKT ACTIVITY

Applicant/Assignee:

Application No.: 12/027454   Filing Date: 07/Feb/2008

Abstract:

Invented are novel heterocyclic carboxamide compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis.

Priority: US20070888586P Applic. Date: 2007-02-07

Inventor: SEEFELD MARK A [US]; ROUSE MEAGAN B [US]; HEERDING DIRK A [US]


Application No.: US20090209899A1  Published: 20/Aug/2009

Title: DELIVERY SYSTEM AND PROCESS

Applicant/Assignee:

Application No.: 12/304960   Filing Date: 15/Jun/2007

Abstract:

A delivery system, including: a material for storing molecules and/or nanoparticles by substantially binding said molecules and/or nanoparticles to said material

means for applying an electric field to said material to release said molecules and/or nanoparticles

and means for applying an ultrasonic signal to said material to transport said molecules and/or nanoparticles through said material to a surface for delivery to an entity.

Priority: US20060814093P Applic. Date: 2006-06-15; WO2007AU00843 Applic. Date: 2007-06-15

Inventor: UNGER HARRY [AU]; UNGER MARK [AU]; MARTIN DONALD [AU]; BULL DAVID JOHN [AU]; ANDREWS CRAIG [AU]


Application No.: US20090209905A1  Published: 20/Aug/2009

Title: COMPOSITIONS COMPRISING CHITIN MICROPARTICLES AND THEIR MEDICAL USES

Applicant/Assignee:

Application No.: 12/339849   Filing Date: 19/Dec/2008

Abstract:

The present invention relates to compositions comprising chitin microparticles and their medical uses, and in particular to compositions for use as vaccines which comprise antigen from an infectious agent, a chitin microparticle preparation, and a further adjuvant.

Priority: WO2007GB02188 Applic. Date: 2007-06-13; US20060815074P Applic. Date: 2006-06-20

Inventor: STRONG PETER [GB]


Application No.: US20090210032A1  Published: 20/Aug/2009

Title: MANUFACTURING METHODS, TESTING METHODS, AND TESTERS FOR INTRA-ORAL ELECTRONICALLY EMBEDDED DEVICES

Applicant/Assignee:

Application No.: 11/572527   Filing Date: 20/Jul/2005

Abstract:

The invention is directed to manufacturing and testing methods of electronic intraoral devices for diagnose, monitor and treat local and systemic diseases and conditions for humans and animals. More specifically, the current invention deals with manufacturing techniques, testing methods and a testing apparatus of mainly three types of intra-oral devices: (a) electro-stimulators for various applications such as treatment of dry mouth by stimulating saliva secretion, apnea, sleeping disorders, eating disorders (obesity, anorexia, etc.) dysphagia and others, (b) drug delivery devices

and (c) bio-sensing and monitoring devices. The common parts or the devices are: (1) art electronic module embedded in the device: (2) or a power source being embedded in the device

(3) the devices (or part of them) being placed in the oral cavity.

Priority: US20040590211P Applic. Date: 2004-07-23; WO2005IL00773 Applic. Date: 2005-07-20

Inventor: BEISKI BEN ZION [IL]; WOLFF ANDY [IL]


Application No.: US20090211573A1  Published: 27/Aug/2009

Title: ENDOTRACHEAL TUBE HOLDER WITH IMPROVED LOCKING DEVICE

Applicant/Assignee:

Application No.: 12/035847   Filing Date: 22/Feb/2008

Abstract:

An endotracheal tube holder assembly is provided. The holder assembly comprises a support strap band for placement around a patient's head or neck region and a flexible linking band for attachment to the support strap band. The flexible linking band further comprises an elongate, central bridge portion, an upper bar portion extending from the central bridge portion, and at least one tab extending laterally from the central bridge portion.

Priority:

Inventor: RUSSO RONALD D [US]


Application No.: US20090211606A1  Published: 27/Aug/2009

Title: METHOD OF CLEANING BOTTLES IN A BOTTLE CLEANING MACHINE, AND AN ARRANGEMENT FOR PERFORMING THE METHOD, AND A BOTTLE CLEANING MACHINE

Applicant/Assignee:

Application No.: 12/389937   Filing Date: 20/Feb/2009

Abstract:

A method of cleaning bottles in a bottle cleaning machine, and an arrangement for performing the method, and a bottle cleaning machine. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. PRG 1.72(b). As stated in 37 C.F.R. PRG 1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading "Abstract of the Disclosure." The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner.

Priority: DE200610039599 Applic. Date: 2006-08-23; WO2007EP07242 Applic. Date: 2007-08-16

Inventor: MOLITOR BERND [DE]; JENDRICHOWSKI KLAUS [DE]


Application No.: US20090214444A1  Published: 27/Aug/2009

Title: POLY AROMATIC SODIUM CHANNEL BLOCKERS

Applicant/Assignee: PARION SCIENCES, INC

Application No.: 12/393252   Filing Date: 26/Feb/2009

Abstract:

Polyaromatic sodium channel blockers represented by the formula: are provided where the structural variables are defined herein. The invention also includes a variety of compositions, combinations and methods of treatment using these inventive sodium channel blockers.

Priority: US20080031466P Applic. Date: 2008-02-26

Inventor: JOHNSON MICHAEL ROSS [US]


Application No.: US20090214450A1  Published: 27/Aug/2009

Title: ORAL TREATMENT COMPOSITIONS AND RELATED METHODS OF MANUFACTURE

Applicant/Assignee: RANIR, LLC

Application No.: 12/370845   Filing Date: 13/Feb/2009

Abstract:

An oral treatment composition that includes a carrier, an active agent and a silicon dioxide compound. The active agent can be a variety of compositions, such as dental whitening or bleaching agents, desensitizing agents, antimicrobials, anti-plaque agents, remineralizing agents, anti-tartar agents, mouth fresheners, and anesthetics. Optionally, a processing aid can be added to the composition to streamline manufacture of the gel. The composition can be formed as a bead in a dental tray so that when a user applies the dental tray to their dental arch, the bead readily spreads over the surfaces of the teeth without the user having to supply significant force to achieve such spreading.

Priority: US20080030729P Applic. Date: 2008-02-22

Inventor: FISHER JEFFREY J [US]; SOLIZ DEBRA C [US]


Application No.: US20090214451A1  Published: 27/Aug/2009

Title: Oral Hygiene Compositions

Applicant/Assignee: INTRINSIQ MATERIALS GLOBAL LIMITED

Application No.: 11/918572   Filing Date: 21/Apr/2006

Abstract:

Oral hygiene compositions suitable for use as dentifrice compositions comprising a silicon abrasive agent are provided.

Priority: GB20050008174 Applic. Date: 2005-04-22; WO2006GB01459 Applic. Date: 2006-04-21

Inventor: CANHAM LEIGH TREVOR [GB]


Application No.: US20090214606A1  Published: 27/Aug/2009

Title: ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES

Applicant/Assignee:

Application No.: 11/919838   Filing Date: 03/May/2006

Abstract:

The present invention relates to antimicrobial, porous particles, especially porous, non-platelet-like SiO2 particles, comprising an organic, or inorganic antimicrobial compound, or composition, with the proviso that the porous particles are not porous SiOz flakes, wherein 0.70

Priority: EP20050103849 Applic. Date: 2005-05-10; WO2006EP61992 Applic. Date: 2006-05-03

Inventor: BUJARD PATRICE [CH]; HOPPE HOLGER [DE]


Application No.: US20090214609A1  Published: 27/Aug/2009

Title: Oral Polyphosphate Compositions

Applicant/Assignee:

Application No.: 12/034882   Filing Date: 21/Feb/2008

Abstract:

The present invention relates to a dentifrice composition comprising: a) a polyphosphate salt in particulate form, the polyphosphate salt comprising a polyphosphate anion comprising at least 10 phosphate units

and b) an orally acceptable carrier

characterised in that the polyphosphate salt has a particle size distribution wherein less than 10% by volume of the salt has a particle size of greater than 160 mum and less than 20% by volume of the salt has a particle size of less than 20 mum. The dentifrice composition has good stability and acceptable mouth feel. The invention further relates to orally acceptable polyphosphate salts for use in such compositions.

Priority:

Inventor: STRAND ROSS [GB]; DE LA HARPE SHANE MICHAEL [GB]; GUNENC PELIN [GB]


Application No.: US20090214628A1  Published: 27/Aug/2009

Title: METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN

Applicant/Assignee:

Application No.: 11/912839   Filing Date: 04/Aug/2006

Abstract:

The present invention relates to compositions and their use for the treatment of human skin, particularly facial skin, to alleviate the symptoms of cosmetic or determatologic skin conditions. The invention relates to compositions for treating and ameliorating skin conditions including acne, rosacea and wrinkling caused by photodamage or conditions related to aging, hormonal imbalances, hyper-pigmentation, melasma, keratosis or the like. The invention can also be used to treat conditions of the scalp such as dandruff. The present invention also relates to compositions that can be used to remove biofilms from contact lenses. More particularly, this invention relates to a composition comprising (a) one or more metasilicate

(b) one or more carbonate

(c) one or more glyconate

and (d) one or more sulfate. The composition may also contain (e) salts, e.g., sea salts and other additives or active agents.

Priority: WO2005IB03665 Applic. Date: 2005-09-27; US20040612919P Applic. Date: 2004-09-27; WO2006IB04122 Applic. Date: 2006-08-04

Inventor: DE RIJK JAN [NL]


Application No.: US20090215703A1  Published: 27/Aug/2009

Title: PAR-2 Agonist

Applicant/Assignee: KOWA COMPANY, LTD

Application No.: 11/909931   Filing Date: 29/Mar/2006

Abstract:

The present invention relates to a pharmaceutical composition for preventing/treating conditions associated with PAR-2. The present invention also relates to a method for preventing/treating the condition using the pharmaceutical composition and use for manufacturing the pharmaceutical composition. The pharmaceutical composition comprises a compound represented by the following general formula (1), salt or solvate thereof and a pharmaceutically acceptable carrier: Ar-CO-AA1-AA2-AA3-AA4-NH-X-Y (1) wherein, Ar represents a phenyl group or an aromatic heterocyclic group optionally having substituent(s): AA1 represents a hydrophobic amino acid: AA2 represents an amino acid absent of substituent (s) having more than two carbon atoms: AA3 represents an amino acid absent of substituent(s) having more than two carbon atoms: AA4 represents a basic amino acid: X represents a straight-chain or branched bivalent saturated aliphatic hydrocarbon group having 1 to 6 carbon atoms: Y represents basic substituent (s)

straight-chain, branched, or cyclic bivalent saturated aliphatic hydrocarbon group having 1 to 6 carbon atoms, or an aromatic hydrocarbon group having 6 to 10 carbon atoms. The compound represented by the general formula (1) has dramatically improved PAR-2 activation potency compared to peptide comprised of 6 amino acids (Tethered receptor agonist peptide: TRAP) in spite of reduction of the number of amino acid.

Priority: US20050665831P Applic. Date: 2005-03-29; WO2006JP306433 Applic. Date: 2006-03-29

Inventor: ISHIWATA HIROYUKI [JP]; KABEYA MOTOTSUGU [JP]; KANKE TORU [JP]


Application No.: US20090215734A1  Published: 27/Aug/2009

Title: METHOD AND SYSTEM FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH NEBULIZED ANTICHOLINERGIC ADMINISTRATIONS

Applicant/Assignee: ELEVATION PHARMACEUTICALS, INC

Application No.: 12/393709   Filing Date: 26/Feb/2009

Abstract:

Inhalation solutions for administration of muscarinic antagonists for the treatment of breathing disorders, such as COPD, are provided.

Priority: US20080031639P Applic. Date: 2008-02-26; US20080080184P Applic. Date: 2008-07-11

Inventor: GERHART WILLIAM [US]


Application No.: US20090215820A1  Published: 27/Aug/2009

Title: NOVEL ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS

Applicant/Assignee:

Application No.: 12/437233   Filing Date: 07/May/2009

Abstract:

This invention relates to novel alkyl substituted piperidine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20040000961 Applic. Date: 2004-06-18; US2005-579060 Applic. Date: 2005-06-14; WO2005EP52731 Applic. Date: 2005-06-14; US20040581359P Applic. Date: 2004-06-22

Inventor: PETERS DAN [DK]; OLSEN GUNNAR M [DK]; NIELSEN ELSEBET OSTERGAARD [DK]; SCHEEL-KRUGER JERGEN [DK]; ERIKSEN BIRGITTE L [DK]


Application No.: US20090215905A1  Published: 27/Aug/2009

Title: Novel substituted aryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors

Applicant/Assignee:

Application No.: 11/658902   Filing Date: 24/Aug/2005

Abstract:

This invention relates to novel substituted aryloxy alkylamines useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20040001290 Applic. Date: 2004-08-26; US20040605175P Applic. Date: 2004-08-30; WO2005EP54151 Applic. Date: 2005-08-24

Inventor: ERIKSEN BIRGITTE L [DK]; PETERS DAN [DK]; NIELSEN ELSEBET OSTERGAARD [DK]; SCHEEL-KRUGER JORGEN [DK]; OLSEN GUNNAR M [DK]


Application No.: US20090216104A1  Published: 27/Aug/2009

Title: USE OF ACID DERIVATIVES OF FLUOROPOLYMERS FOR FOULING-RESISTANT SURFACES

Applicant/Assignee:

Application No.: 12/064273   Filing Date: 28/Aug/2006

Abstract:

The presently disclosed subject matter describes acid-derivatized perfluoropolyether (PFPE) materials and their use as coatings, sealants, and flexible fillers for devices, apparatuses, and structural parts for a variety of medical applications, and as coatings, sealants, flexible fillers, and structural parts for vessels, structures, and machinery exposed to a marine environment.

Priority: US20050711493P Applic. Date: 2005-08-26; WO2006US33699 Applic. Date: 2006-08-28

Inventor: DESIMONE JOSEPH M [US]; WILLIAMS MICHAEL S [US]; PORTNOW LAUREN [US]; WOOD COLIN [US]; ZHOU ZHILIAN [US]; BAUCOM EVERETT [US]; ROTHROCK GINGER DENISON [US]


Application No.: US20090216170A1  Published: 27/Aug/2009

Title: SYSTEM AND METHOD FOR HEALING A WOUND AT A TISSUE SITE

Applicant/Assignee:

Application No.: 12/394618   Filing Date: 27/Feb/2009

Abstract:

Provided herein is a system and method for facilitating removal of a drape from a tissue site. One aspect provides a system comprising a drape, and adhesive layer, and a release agent, where the system is adapted to be coupled to a tissue site and released therefrom upon or after exposure to an external stimulus. Another aspect provides a method for application and removal of a drape using less force than required with a conventional drape.

Priority: US20080032014P Applic. Date: 2008-02-27

Inventor: ROBINSON TIMOTHY MARK [GB]; KIESWETTER KRISTINE [US]; MCNULTY AMY [US]


Application No.: US20090216323A1  Published: 27/Aug/2009

Title: MODULATING BUTTRESS SALINE MAMMARY PROSTHESIS

Applicant/Assignee:

Application No.: 12/360979   Filing Date: 28/Jan/2009

Abstract:

A saline-filled breast prosthesis has enhanced performance by virtue of having tactile characteristics approximating those of gel-filled implants. The invention retains all the benefits of the recognized safety profile, straight-forward construction, and broad clinical indications for saline implants. An enhanced implantable mammary prosthesis comprises a shell, a slurry filler compartment interior to the shell containing slurry filler, a fluid compartment, the fluid compartment being deformable from a neutral profile under pressure from the slurry filler and which recoils to the neutral profile when not under pressure, a reservoir, the reservoir being disposed external to the shell, the reservoir and fluid compartment being fluidically coupled by a port, and a limiting membrane region disposed between the fluid compartment and the reservoir.

Priority: US20080024405P Applic. Date: 2008-01-29

Inventor: LEDERGERBER WALTER J [US]


Application No.: US20090217397A1  Published: 27/Aug/2009

Title: Cre-lox based gene knockdown constructs and methods of use thereof

Applicant/Assignee:

Application No.: 11/808553   Filing Date: 11/Jun/2007

Abstract:

The present invention relates to vectors, compositions and methods for conditional, Cre-lox regulated, RNA interference. The vectors allow for spatial and temporal control of miRNA expression in vivo.

Priority: US20060812608P Applic. Date: 2006-06-12

Inventor: STERN PATRICK [US]; HYNES RICHARD [US]


Application No.: US20090218194A1  Published: 03/Sep/2009

Title: BOTTLE INVERTING AND BOTTLE DRAINING STATION CONFIGURED TO DRAIN RINSED BOTTLES FROM A RINSER IN A CONTAINER FILLING PLANT

Applicant/Assignee:

Application No.: 12/269330   Filing Date: 12/Nov/2008

Abstract:

A bottle converting and bottle draining station configured to drain rinsed bottles from a rinser in a container filling plant. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. PRG 1.72(b). As stated in 37 C.F.R. PRG 1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading "Abstract of the Disclosure." The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner.

Priority: DE200610022465 Applic. Date: 2006-05-13; WO2007EP04178 Applic. Date: 2007-05-11

Inventor: MENKE HERBERT [DE]; WEISGERBER MARTIN [DE]; POHL RALPH [DE]


Application No.: US20090218266A1  Published: 03/Sep/2009

Title: WATER TREATMENT AND METHODS OF USE

Applicant/Assignee:

Application No.: 12/041145   Filing Date: 03/Mar/2008

Abstract:

The present invention describes a novel antimicrobial ion delivery system (IDS) article, methods of making the article, and its applications in water disinfection. The novel IDS entails a source of oligodynamic metal ions embedded in a matrix that allows for the release of metal ions in water at biocidals concentrations. The preferred IDS contains particles made of metallic alloys and bound to a matrix that ensures the controlled release of ions in water. The novel IDS is safe for use in animals and humans and it is environment friendly and biodegradable.

Priority:

Inventor: SAWAFTA REYAD [US]; HAIK YOUSEF [US]


Application No.: US20090220514A1  Published: 03/Sep/2009

Title: ADAM10 and its Uses Related to Infection

Applicant/Assignee:

Application No.: 12/160862   Filing Date: 16/Jan/2007

Abstract:

The present invention relates to a protein, ADAM10, ADAM10 nucleic acid sequences and ADAM10 proteins encoded by these sequences that are involved in infection by one or more pathogen such as a virus, a parasite, a bacteria or a fungus or are otherwise associated with the life cycle of a pathogen.

Priority: US20060847072P Applic. Date: 2006-09-25; US20060758887P Applic. Date: 2006-01-13; US20060832019P Applic. Date: 2006-07-20; WO2007US01108 Applic. Date: 2007-01-16

Inventor: RUBIN DONALD H [US]; HODGE THOMAS [US]; MURRAY JAMES [US]


Application No.: US20090220561A1  Published: 03/Sep/2009

Title: COMPOSITIONS COMPRISING NANOSTRUCTURES FOR CELL, TISSUE AND ARTIFICIAL ORGAN GROWTH, AND METHODS FOR MAKING AND USING SAME

Applicant/Assignee:

Application No.: 11/913062   Filing Date: 28/Apr/2006

Abstract:

The invention provides articles of manufacture comprising biocompatible nanostructures comprising nanotubes and nanopores for, e.g., organ, tissue and/or cell growth, e.g., for bone, kidney or liver growth, and uses thereof, e.g., for in vitro testing, in vivo implants, including their use in making and using artificial organs, and related therapeutics. The invention provides lock-in nanostructures comprising a plurality of nanopores or nanotubes, wherein the nanopore or nanotube entrance has a smaller diameter or size than the rest (the interior) of the nanopore or nanotube. The invention also provides dual structured biomaterial comprising micro- or macro-pores and nanopores. The invention provides biomaterials having a surface comprising a plurality of enlarged diameter nanopores and/or nanotubes.

Priority: US20050676602P Applic. Date: 2005-04-28; US20050710051P Applic. Date: 2005-08-22; US20050710245P Applic. Date: 2005-08-22; US20060773885P Applic. Date: 2006-02-15; US20060773868P Applic. Date: 2006-02-15; WO2006US16471 Applic. Date: 2006-04-28

Inventor: JIN SUNGHO [US]; OH SEUNGHAN [US]


Application No.: US20090220912A1  Published: 03/Sep/2009

Title: Dental Finishing, Sanding and/or Polishing Floss

Applicant/Assignee:

Application No.: 12/467592   Filing Date: 18/May/2009

Abstract:

An abrading dental floss is characterized by dental floss formed of a fiber or fibrous material having a dental abrasive on at least a portion thereof suitable for polishing, sanding and/or finishing dental restorative material such as dental resin. The fiber is preferably a synthetic material. The dental abrading material is impregnated into or provided onto the dental floss. In one form, the dental abrading floss has an abrading section situated between lengths of the dental floss. The abrading polishing section may be formed of an alternating pattern of non-abrasive portions and abrasive portions along a length of the floss. The abrasive portions may be of a single grit or texture of the dental abrasive or may be of different grits of the dental abrasive. In another form, the dental abrading floss has a single grit of a dental abrasive along its entire length. In yet another form, the dental abrading floss comprises a plastic sheet of having a dental abrasive thereon or therein situated between lengths of the dental floss. The dental abrasive may be of a single grit or different grits of the dental abrasive. For different grits of the dental abrasive, it is preferred, but not necessary, that they gradually change in grit size.

Priority: US2007-891820 Applic. Date: 2007-08-13; US20060837482P Applic. Date: 2006-08-14

Inventor: ALLEN JEFFREY T [US]


Application No.: US20090220919A1  Published: 03/Sep/2009

Title: Dental Bleaching Gel Composition Containing Vegetative Enzymes

Applicant/Assignee:

Application No.: 12/191628   Filing Date: 14/Aug/2008

Abstract:

Priority: US20080032078P Applic. Date: 2008-02-28

Inventor: YANG JEN-CHANG [TW]; HUANG YU-LIN [TW]; WU HONGDA [TW]; YANG YEN CHENG [TW]; LEE SHENG-YANG [TW]


Application No.: US20090221413A1  Published: 03/Sep/2009

Title: STRENGHTENED, PRESSABLE CERAMIC COMPOSITIONS FOR DENTAL PURPOSES

Applicant/Assignee: HERAEUS HOLDING GMBH

Application No.: 12/399234   Filing Date: 06/Mar/2009

Abstract:

Pressable glass-ceramic compositions for dental purposes of the composition I, II or III I II III (percent by weight) (percent by weight) (percent by weight)

ZrO2 17-70% ZrO2/ 15-70% Al2O3 15-70% Al2O3 SiO2 17-59% SiO2 17-59%

SiO2 17-59% Al2O3 2-15% ZrO2 32-15% ZrO2 2-15% Y2O3 0-6% Y2O3 0-6% Y2O3 0-6% K2O 3-12.5% K2O 3-12.5% K2O 3-12.5% Na2O 0.2-8.5% Na2O 0.2-8.5% Na2O 0.2-8.5% Li2O 0-1.5% Li2O 0-1.5% Li2O 0-1.5% CaO 0.3-2% CaO 0.3-2% CaO 0.3-2%

B2O3 0.1-5% B2O3 0.1-5% B2O3 0.1-5% F 0-2.5% F 0-2.5% F 0-2.5% CeO2 0.2-2% CeO2 0.2-2% CeO2 0.2-2% TiO2 0-1.5% TiO2 0-1.5% TiO2 0-1.5%

are particularly suitable for the manufacturing of ceramic veneer frames.

Priority: DE200410010138 Applic. Date: 2004-02-27; US2005-052396 Applic. Date: 2005-02-07

Inventor: STEIDL JURGEN [DE]


Application No.: US20090223527A1  Published: 10/Sep/2009

Title: Apparatus that improves discovery of cancer mass, and reduces inflammation - onset of symptoms of carpal tunnel syndrome or arthritis - tactile deficit of fingers, and increases discovery of foreign mass in breast and other self examinations

Applicant/Assignee:

Application No.: 12/387925   Filing Date: 09/May/2009

Abstract:

An apparatus to increase identification of cancer mass in subcutaneous tissue, by palpation by self examination, to accommodate disability, to increase therapy of medical and physical recovery and treatment, and method of using devices or compounds which reduce onset of symptoms of median nerve entrapment or carpal tunnel syndrome or repetitive stress syndrome, reduce tactile deficit of fingers, and as well as many other applications. This includes improving the efficiency of the movement of the fingers, reducing the inflammation in the carpal canal, reducing the tendon excursion in the carpal canal, reducing finger flexion, reducing loss of nerve sensation, reducing loss of tactile sensation, increasing tactile sensitivity of the fingers, increasing movement of the dorsal interossei muscles of the hand, increasing movement of the volar interossei palmer muscles of the hand, and increasing movement of the lumbrical muscles of fingers.

Priority: US2004-780476 Applic. Date: 2004-02-16

Inventor: CHOATE JOHN IRVAN MORITZKY [US]


Application No.: US20090226533A1  Published: 10/Sep/2009

Title: Functional Milk Fraction for Use Against Dental Erosion

Applicant/Assignee: FRIESLAND BRANDS B.V

Application No.: 11/573431   Filing Date: 05/Aug/2005

Abstract:

The present invention relates to a functional milk fraction which can be used to reduce negative effects associated with the oral uptake of acidic foods and beverages, to a method of isolating said specific milk fraction and to the use of this milk fraction in compositions for oral care. The functional milk fraction can be used in edible products, especially to counteract the negative effects of the consumption of acidic foods and beverages.

Priority: EP20040077265 Applic. Date: 2004-08-09; WO2005NL00573 Applic. Date: 2005-08-05

Inventor: BOS ROLF [NL]; BEERNINK ROY [NL]; OUDEMAN EVERT [NL]


Application No.: US20090226855A1  Published: 10/Sep/2009

Title: Dental furnace

Applicant/Assignee: IVOCLAR VIVADENT AG

Application No.: 12/380905   Filing Date: 05/Mar/2009

Abstract:

The invention relates to a dental furnace wherein a firing chamber is heated up in a first heating-up period at a first heating-up rate of more than 50 DEG K/min, in particular more than 100 DEG K/min, which heats the furnace to at least 1000 DEG C., in particular to 1100-1250 DEG C. The first heating-up period is followed by an intermediate heating period, which is at least five minutes long, in particular at least ten minutes long, the gradient or heating-up rate of which is adapted to the material to be sintered in the dental furnace (10), and wherein this is followed by an end heating-up period (44) during which heating up is effected at a heating-up rate of more than 30 DEG K/min, in particular approximately 50 DEG K/min, and wherein during this the furnace temperature is held for at least five minutes, in particular for at least 25 minutes, above the temperature toward the end of the first heating-up period, and wherein forced cooling of the furnace (10) is performed after this.

Priority: DE200810012578 Applic. Date: 2008-03-05

Inventor: ROHNER GOTTFRIED [CH]; POKORNY WALTER [AT]; GRUNENFELDER ROBERT [LI]; ROTHBRUST FRANK [AT]


Application No.: US20090227594A1  Published: 10/Sep/2009

Title: ALIPHATIC AMIDE & ESTER PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS

Applicant/Assignee:

Application No.: 11/573413   Filing Date: 18/Aug/2005

Abstract:

The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.

Priority: US20040602327P Applic. Date: 2004-08-18; WO2005US29275 Applic. Date: 2005-08-18

Inventor: JOHNSON MICHAEL R [US]


Application No.: US20090227613A1  Published: 10/Sep/2009

Title: Novel 3-Aza-Spiro[5.5]Undecane Derivatives and Their Use As Monoamine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee: NEURO SEARCH A/S

Application No.: 11/922917   Filing Date: 28/Jun/2006

Abstract:

This invention relates to novel 3-aza-spiro[5.5]undecane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000961 Applic. Date: 2005-06-28; US20050694680P Applic. Date: 2005-06-29; WO2006EP63634 Applic. Date: 2006-06-28

Inventor: ERIKSEN BIRGITTE L [DK]; PETERS DAN [SE]; NIELSEN ELSEBET OSTERGAARD [DK]; REDROBE JOHN PAUL [DK]


Application No.: US20090227614A1  Published: 10/Sep/2009

Title: Modulators of Muscarinic Receptors

Applicant/Assignee:

Application No.: 12/224270   Filing Date: 22/Feb/2007

Abstract:

The present invention relates to modulators of muscarnic receptors of formula (I). The present invention also provides impositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

Priority: US20060775501P Applic. Date: 2006-02-22; US20060775524P Applic. Date: 2006-02-22; WO2007US04745 Applic. Date: 2007-02-22

Inventor: MAKINGS LEWIS R [US]; BLANCO MIGUEL GARCIA-GUZMAN [US]; HURLEY DENNIS J [US]; DRUTU IOANA [US]; RAFFAI GABRIEL [US]; BERGERON DANIELE M [US]; NAKATANI AKIKO [US]; TERMIN ANDREAS P [US]; SILINA ALINA [US]


Application No.: US20090227699A1  Published: 10/Sep/2009

Title: Photopolymerizable dental composition with suppressed change in color tone by monomer

Applicant/Assignee: KABUSHIKI KAISHA SHOFU

Application No.: 12/379925   Filing Date: 04/Mar/2009

Abstract:

An object of the present invention is to provide a dental composition with less change of color tone before and after curing and less color change after curing, and also with excellent thin-layer surface curability. Disclosed is a dental composition comprising 0.01 to 10 parts by weight of at least one kind of (a) a visible light.-photopolymerization catalyst compound and one or more kinds of (b) di(meth)acrylate compounds represented by the general formula (I): wherein R1 and R2 each independently represent hydrogen or a methyl group, and a repeating unit number n of an ethylene oxide group is from 9 to 50.

Priority: JP20080052963 Applic. Date: 2008-03-04

Inventor: UCHIDA JUN [JP]; MIZUNO MITSUHARU [JP]; TERAMAE MITSUJI [JP]


Application No.: US20090227700A1  Published: 10/Sep/2009

Title: Photopolymerizable dental composition with less change in color tone before and after curing

Applicant/Assignee: KABUSHIKI KAISHA SHOFU

Application No.: 12/379926   Filing Date: 04/Mar/2009

Abstract:

An object of the present invention is to provide a photopolymerizable dental composition which causes less change in a color tone before and after curing and exhibits excellent photopolymerizability to irradiation in a wide wavelength range, and has also excellent thin-layer surface curability, and to provide a photopolymerization initiator used therefor. Disclosed is a visible light-polymerizable dental composition which does not substantially contain an amine compound as a photosensitizer, comprising 0.01 to 10 parts by weight of a (bis)acylphosphine oxide compound, 0.01 to 10 parts by weight of an alpha-diketone compound and 100 parts by weight of a polymerizable monomer.

Priority: JP20080052962 Applic. Date: 2008-03-04

Inventor: UCHIDA JUN [JP]; MIZUNO MITSUHARU [JP]; TERAMAE MITSUJI [JP]


Application No.: US20090229062A1  Published: 17/Sep/2009

Title: DENTAL HYGIENE DEVICE

Applicant/Assignee:

Application No.: 12/404528   Filing Date: 16/Mar/2009

Abstract:

A dental device is disclosed, wherein the dental device includes a base portion, a maneuverable head portion, and a plurality of bristles for improved dental cleaning and minimization of physical movement associated with dental cleaning.

Priority: US20080036982P Applic. Date: 2008-03-16

Inventor: FILBY ELIZABETH [US]


Application No.: US20090229616A1  Published: 17/Sep/2009

Title: APPARATUS FOR STABILIZING AN AIRWAY TUBE

Applicant/Assignee:

Application No.: 12/299027   Filing Date: 26/Apr/2007

Abstract:

An airway tube holder (10) has a face plate assembly to fix an airway tube (24). The assembly comprises a face plate (20) for placement over the mouth of a patient. The face plate (20) has a channel (22) including an open end (23) and a closed end (26) in which the tube (24) is fixedly positioned. A tube holding block (30) is integrally mounted to the face plate (20). The block (30) has a securing means (38, 40, 41) mounted in the tube holding block (30). A clamp (41) is secured to a screw (40) of the securing means by a loop (44) encircling the screw (40). A folded strip (106) is attached to the end of a headband (18) so secure the holder to a patient, and forms hooked portions facing in opposite directions. The block (30) is flexible enough to absorb an over-tightening of the screw (40).

Priority: NO20060001891 Applic. Date: 2006-04-26; WO2007NO00147 Applic. Date: 2007-04-26

Inventor: LILAND FRODE [NO]


Application No.: US20090230013A1  Published: 17/Sep/2009

Title: User-Customizable Dosing System

Applicant/Assignee: THE PROCTER & GAMBLE COMPANY

Application No.: 12/405438   Filing Date: 17/Mar/2009

Abstract:

A customizable dosing system is provided, comprising a primary container comprising at least one enclosure, the enclosure containing a dosage unit comprising an active

indicia for selection or deselection of one or more of the dosage units and actives

wherein the indicia enables a user to select a system and one or more dosage units and actives appropriate to a user's needs. Also provided are methods of customizing dosage and treatment, and kits containing a customizable dosing system and one or more complimentary products.

Priority: US20080069723P Applic. Date: 2008-03-17

Inventor: BORN JASON ALAN [US]; DOAN DEBORAH M [US]; CRISS SUSAN ELAINE [US]


Application No.: US20090232422A1  Published: 17/Sep/2009

Title: BAG WITH IMPROVED FEATURES

Applicant/Assignee:

Application No.: 12/304851   Filing Date: 29/Jun/2007

Abstract:

The bag for receiving refuse may include a bag body, the bag body including an inside surface, an outside surface, and a rim defining a mouth. The bag may also include a first strip of material disposed on the inside surface of the bag body proximate the rim. The strip may include an inside surface, an outside surface that faces the inside surface of the body, a top edge, and a bottom edge. The bag may also include a front wall, a back wall, and a hem, the hem including a drawstring. The strip may include a printed design. The design could be letters, numbers, pictures, writing, or any other design. When the bag is inserted into a trash receptacle such that the rim of the bag is folded over the rim of the receptacle, the printed design is visible from outside the receptacle.

Priority: US20060831039P Applic. Date: 2006-07-14; WO2007US72471 Applic. Date: 2007-06-29

Inventor: BROERING SHAUN T [US]; TOERNER KARIN L [US]; SNORECK CHARLES B [US]; MACK-ROBLES NANCY M [US]; WALDRON MATTHEW W [US]; FRASER ROBERT W [US]


Application No.: US20090232745A1  Published: 17/Sep/2009

Title: LICORICE LOLLIPOP THAT INHIBITS DENTAL CARIES FORMATION

Applicant/Assignee: INTELLIHERB, INC

Application No.: 12/404119   Filing Date: 13/Mar/2009

Abstract:

This invention pertains to the discovery that certain extracts of licorice, particularly when formulated as a candy or lollipop or other means that provides an extended release (e.g., greater than about 4 minutes) to the oral cavity significantly inhibits the formation of dental caries in a human subject.

Priority: US20080036792P Applic. Date: 2008-03-14

Inventor: ANDERSON MAXWELL H [US]


Application No.: US20090232749A1  Published: 17/Sep/2009

Title: Compositions for the acute and/or long term treatment of periodontal diseases

Applicant/Assignee: EUROPEAN NATURAL PRODUCTS

Application No.: 11/720768   Filing Date: 24/Nov/2005

Abstract:

Composition comprising a mixture of radix polygoni multiflori, Fructus Corni, cuscuta japonica, rehmannia glutinosa, licorice, asparagine, Derla andrographis and a composition comprising a mixture of Salvida persica, achyranthes aspera, spilanthes acmela, clove, picus Bengalensis, acacia nilotioca resen, eucalyptus, mint, green tea, bamboo silica for the acute and/or long term treatment of of microbial infections, in particular of oral pathogenic micro-organisms, in particular dental caries, periodontosis, gingivitis, gum disease, gum bleeding and/or plaque reduction.

Priority: WO2004IB04398 Applic. Date: 2004-12-03; WO2005IB03534 Applic. Date: 2005-11-24

Inventor: ADLER RICHARD JAY [ES]


Application No.: US20090232773A1  Published: 17/Sep/2009

Title: Method for Distinguishing Mesenchymal Stem Cell Using Molecular Marker and Use Thereof

Applicant/Assignee:

Application No.: 11/887362   Filing Date: 30/Mar/2006

Abstract:

Disclosed is a method for distinguishing a mesenchymal stem cell comprising, using at least one gene selected from the genes having the nucleotide sequences indicated by the accession numbers shown in Table 1 as a distinguish marker, detecting the difference in expression of the distinguish marker between a mesenchymal stem cell and a connective tissue cell to distinguish the mesenchymal stem cell from the connective tissue cell. This method enables to distinguish an undifferentiated mesenchymal stem cell from other connective tissue cell such as fibroblasts, osteoblasts, chondrocytes and adipose cells with good accuracy. A mesenchymal stem cell given by this method or a composition comprising the mesenchymal stem sell can be used as a therapeutic for use in the regenerative medicine.

Priority: JP20050104563 Applic. Date: 2005-03-31; WO2006JP306658 Applic. Date: 2006-03-30

Inventor: KATO YUKIO [JP]; KAWAMOTO TAKESHI [JP]; TSUJI KOICHIRO [JP]; IGARASHI AKIRA [JP]; SHIMIZU MASAKAZU [JP]


Application No.: US20090232855A1  Published: 17/Sep/2009

Title: Percutaneous controlled releasing material using nano-sized polymer particles and external application agent containing the same

Applicant/Assignee:

Application No.: 09/878712   Filing Date: 11/Jun/2001

Abstract:

A percutaneous releasing material and agent having characteristics that include a high stability of an active agent in the formulation, a high topical absorption rate, decreased irritation on the skin, and an increased tactile comfort. The percutaneous releasing material incorporates an external application agent composition that is prepared by using nanometer-sized polymer particles, i.e., particles having a size or diameter between approximately 1 nm and approximately 500 nm, and more preferably having a size between about 30 nm and about 150 nm. Further, the percutaneous releasing material and agent according to the present invention incorporate polymer particles that preferably contain a physiologically active agent that more readily penetrates through the stratum corneum to the upper layer of the dermis, whereby the physiologically active agent is effused into the skin while staying in the upper layer of dermis.

Priority: KR20010019869 Applic. Date: 2001-04-13

Inventor: KWON SUN SANG [KR]; YOO BYUNG HEE [KR]; NAM YOON SUNG [KR]; KIM BAE HWAN [KR]; KU BONG SEOK [KR]; HAN SANG HOON [KR]; CHANG IH SEOP [KR]; LEE JONG SUK [KR]


Application No.: US20090232872A1  Published: 17/Sep/2009

Title: METHOD AND APPARATUS FOR MINIMIZING HEAT, MOISTURE, AND SHEAR DAMAGE TO MEDICANTS AND OTHER COMPOSITIONS DURING INCORPORATION OF SAME WITH EDIBLE FILMS

Applicant/Assignee:

Application No.: 12/251349   Filing Date: 14/Oct/2008

Abstract:

A medicant composition is provided. The composition includes a film layer and a powder matrix layer. The powder matrix layer includes a medicant. The powder matrix layer is applied to the film layer by admixing particulate to form a powder matrix and by then applying the powder matrix to the film layer by any desired method. The composition of the powder matrix is varied to alter the dissolution rate of the medicant, the adhesion of the medicant composition, and other physical properties of the powder matrix. The powder matrix layer can be cured.

Priority: US2003-706810 Applic. Date: 2003-11-12; US20020426598P Applic. Date: 2002-11-14

Inventor: DAVIDSON ROBERT S [US]; KEHOE GARY S [US]


Application No.: US20090232905A1  Published: 17/Sep/2009

Title: ESSENTIAL OILS BASED CLEANING AND DISINFECTING COMPOSITIONS

Applicant/Assignee: OHSOCLEAN, INC

Application No.: 12/335145   Filing Date: 15/Dec/2008

Abstract:

Cleaning and disinfecting compositions for cleaning, disinfecting and sanitizing inanimate and animate surfaces are provided. The cleaning and disinfecting compositions contain thyme oil or thyme oil and origanum oil, a salt of a transition metal, sodium dioctyl sulfosuccinate and water. The cleaning and disinfecting compositions are surprisingly stable and as such, they may be provided to consumers in the undiluted state. The cleaning and disinfecting compositions are botanical, environmentally sustainable, non-toxic and mildly scented.

Priority: US2006-555875 Applic. Date: 2006-11-02

Inventor: WEISS LARRY [US]; DEATH S SAMUEL [CA]


Application No.: US20090233252A1  Published: 17/Sep/2009

Title: ASSEMBLIES, METHODS, AND KITS INCLUDING A COMPRESSIBLE MATERIAL

Applicant/Assignee:

Application No.: 12/428989   Filing Date: 23/Apr/2009

Abstract:

The present invention provides assemblies, kits, and methods including a compressible material. Optionally, a hardenable dental composition (e.g., an adhesive or primer) is in contact with the compressible material for bonding a dental article (e.g., an orthodontic appliance) to a tooth structure. Removal of excess hardenable and/or hardened dental composition, if desired, can be facilitated for embodiments in which the hardenable dental composition is an unfilled or a lightly filled composition.

Priority: US2006-551823 Applic. Date: 2006-10-23

Inventor: CINADER JR DAVID K [US]


Application No.: US20090233860A1  Published: 17/Sep/2009

Title: LYTIC DOMAIN FUSION CONSTRUCTS AND METHODS OF MAKING AND USING SAME

Applicant/Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY & AGRICULTURAL & MECHANICAL COLLEGE ESPERANCE PHARMACEUTICALS

Application No.: 12/398958   Filing Date: 05/Mar/2009

Abstract:

The invention relates to fusion constructs, methods of using fusion constructs and methods of treating undesirable or aberrant cell proliferation or hyperproliferative disorders, such as tumors, cancers, neoplasia and malignancies.

Priority: US2009-359906 Applic. Date: 2009-01-26; US20080023377P Applic. Date: 2008-01-24

Inventor: LEUSCHNER CAROLA [US]; ALILA HECTOR [US]


Application No.: US20090233861A1  Published: 17/Sep/2009

Title: LYTIC DOMAIN FUSION CONSTRUCTS AND METHODS OF MAKING AND USING SAME

Applicant/Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE ESPERANCE PHARMACEUTICALS

Application No.: 12/398965   Filing Date: 05/Mar/2009

Abstract:

The invention relates to fusion constructs, methods of using fusion constructs and methods of treating undesirable or aberrant cell proliferation or hyperproliferative disorders, such as tumors, cancers, neoplasia and malignancies.

Priority: US2009-359906 Applic. Date: 2009-01-26; US20080023377P Applic. Date: 2008-01-24

Inventor: LEUSCHNER CAROLA [US]; ALILA HECTOR [US]


Application No.: US20090233970A1  Published: 17/Sep/2009

Title: COMBINED NSAID AND ACID BLOCKER FORMULATION AND METHOD

Applicant/Assignee:

Application No.: 12/046327   Filing Date: 11/Mar/2008

Abstract:

The present invention is directed to co-administration of a non-steroidal anti-inflammatory agent (NSAID) and acid blocking agent for the treatment of pain and inflammation with reduced gastrointestinal irritation. A pharmaceutical composition suitable for the co-administration contains a therapeutically effective amount of at least one non-steroidal anti-inflammatory agent, and a therapeutically effective amount of at least one acid blocking agent. A ratio of the non-steroidal anti-inflammatory agent to acid blocking agent in the composition is within a range that provides greater pain relief and reduction of inflammation with less gastrointestinal irritation than that obtainable by the administration of the non-steroidal anti-inflammatory agent or acid blocking agent alone. Examples of pharmaceutical compositions for co-administration of the agents are those containing ibuprofen and ranitidine ("ibudine"), as well as naproxen and ranitidine ("naprodine").

Priority:

Inventor: NICKELL ROBERT P [US]


Application No.: US20090234044A1  Published: 17/Sep/2009

Title: Method for Producing Composites That Can Be Used in Dentistry

Applicant/Assignee: IVOCLAR VIVADENT AG

Application No.: 12/084735   Filing Date: 09/Nov/2006

Abstract:

The present invention relates to a process for the preparation of composites which can be used in the dental field, in which a) mono- or polyfunctional monomers dissolved in a solvent are polymerized to give a polymer gel thoroughly swollen with the solvent, b) the polymer gel produced is subjected to preliminary size reduction, c) a reactive gel is subsequently prepared by the polymer gel, subjected to preliminary size reduction, incorporating a polymerizable monomer or a mixture of polymerizable monomers in the polymer gel while simultaneously removing the solvent, and d) a dental composite is prepared from the reactive gel thus obtained.

Priority: DE200510053954 Applic. Date: 2005-11-11; WO2006EP68310 Applic. Date: 2006-11-09

Inventor: RHEINBERGER VOLKER [LI]; HAGENBUCH KONRAD [CH]; DELLAFIOR PETRA [AT]


Application No.: US20090238763A1  Published: 24/Sep/2009

Title: HIGH PENETRATION COMPOSITIONS AND USES THEREOF

Applicant/Assignee:

Application No.: 12/351804   Filing Date: 09/Jan/2009

Abstract:

The present invention relates to compositions and uses of novel high penetration compositions or high penetration prodrugs (HPP), in particular HPPs for non-steroidal anti-inflammatory agents (NSAIAs), which are capable of crossing biological barriers with high penetration efficiency. The HPPs herein are capable of being converted to parent active drugs or drug metabolites after crossing the biological barrier and thus can render treatments for the conditions that the parent drugs or metabolites can. Additionally, due to the ability of penetrating biological barriers, the HPPs herein are capable of reaching areas that parent drugs may not be able to access or to render a sufficient concentration at the target areas and therefore render novel treatments. The HPPs herein can be administered to a subject through various administration routes. For example, the HPPs can be locally delivered to an action site of a condition with a high concentration due to their ability of penetrating biological barriers and thus obviate the need for a systematic administration. For another example, the HPPs herein can be systematically administer to a biological subject and enter the general circulation with a faster rate.

Priority: WO2006IB52318 Applic. Date: 2006-07-09; WO2006IB52461 Applic. Date: 2006-07-18; WO2006IB52549 Applic. Date: 2006-07-25; WO2006IB52563 Applic. Date: 2006-07-26; WO2006IB52575 Applic. Date: 2006-07-27; WO2006IB52732 Applic. Date: 2006-08-08; WO2006IB52815 Applic. Date: 2006-08-15; WO2006IB53090 Applic. Date: 2006-09-03; WO2006IB53741 Applic. Date: 2006-10-11

Inventor: YU CHONGXI [US]; XU LINA [CN]


Application No.: US20090238769A1  Published: 24/Sep/2009

Title: Compositions Comprising Nonionic And Zwittterionic Surfactants

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/053222   Filing Date: 21/Mar/2008

Abstract:

An foaming agent comprising a non-ionic surfactant, zwitterionic surfactant, and free of anionic surfactants which is suitable for use in personal care products, e.g., dentifrice compositions, e.g., for use in the treatment and/or alleviation of xerostomia.

Priority:

Inventor: JOZIAK MARILOU [US]; NESTA JASON [US]


Application No.: US20090238775A1  Published: 24/Sep/2009

Title: MONO-, DI- AND POLYOL ALKOXYLATE PHOSPHATE ESTERS IN ORAL CARE FORMULATIONS AND METHODS FOR USING SAME

Applicant/Assignee: RHODIA INC

Application No.: 12/471439   Filing Date: 25/May/2009

Abstract:

This invention relates to a composition useful as an oral care composition comprising an organophosphate material, additional oral care composition ingredients, for example, a surfactant agent, and optionally an abrasive agent.

Priority: US2008-137647 Applic. Date: 2008-06-12; US20070943490P Applic. Date: 2007-06-12

Inventor: FUTTERER TOBIAS JOHANNES [US]; HOUGH LAWRENCE ALAN [US]; REIERSON ROBERT LEE [US]


Application No.: US20090238777A1  Published: 24/Sep/2009

Title: High Fluoride Ion Recovery Compositions

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/053233   Filing Date: 21/Mar/2008

Abstract:

Compositions having high fluoride ion recovery comprising a hydrocolloid, a heteropolysaccharide, a PVME/MA copolymer, and a fluoride ion source and use thereof, e.g., in the treatment of xerostomia and/or sensitive teeth.

Priority:

Inventor: JOZIAK MARILOU [US]; NESTA JASON [US]


Application No.: US20090238778A1  Published: 24/Sep/2009

Title: TOOTH WHITENING COMPOSITIONS, DELIVERY SYSTEMS AND METHODS

Applicant/Assignee:

Application No.: 12/051016   Filing Date: 19/Mar/2008

Abstract:

The present invention is directed to tooth whitening compositions that are capable of being activated by light energy, where the compositions include a safe and effective amount of riboflavin or a derivative of riboflavin, from about 0.1 to about 50 percent by weight of a bleaching agent and a water-soluble liquid phase

to systems for delivering the photoactivatable tooth whitening compositions to the surface of the teeth, and methods of whitening teeth that include the steps of exposing the photoactivatable whitening composition to light energy under conditions effective to photoactivate the tooth whitening composition and maintaining the composition in contact with the teeth under conditions effective to whiten teeth.

Priority:

Inventor: MORDAS CAROLYN J [US]; GAMBOGI ROBERT J [US]


Application No.: US20090238779A1  Published: 24/Sep/2009

Title: Dental Treatment Compositions and Conformable Dental Treatment Trays Using the Same

Applicant/Assignee: CAO GROUP, INC

Application No.: 12/329582   Filing Date: 06/Dec/2008

Abstract:

The present invention is a formable dental treatment tray utilizing poly(2-ethyl-2-oxazoline) and a gelatinous active. Blending of the active is accomplished by mixing the Poly(2-ethyl-2-oxazoline) with an active ingredient, such as a peroxide like hydrogen peroxide, carbamide peroxide, sodium perborate, or sodium percarbonate, usually also with water or an appropriate organic solvent. Peroxide concentrations in these new gels can reach a 30% concentration of hydrogen peroxide while maintaining a shelf life of six months at room temperature without developing peroxide decomposition. The gels are applied to an appropriate backing and dried to a gelatinous state. In use, the active is hydrated and regains adhesiveness. Then the tray is pressed and formed around a user's dental arch to form the customizable tray. Multiple active ingredients may be used, with or without peroxide, for accomplishing desired treatment regimens.

Priority: US2006-307463 Applic. Date: 2006-02-08

Inventor: JENSEN STEVEN D [US]; CAO DENSEN [US]


Application No.: US20090238889A1  Published: 24/Sep/2009

Title: Hyper-Branched Polymers for the Provision of Hygienic Characteristics

Applicant/Assignee: HENKEL AG & CO. KGAA

Application No.: 12/406243   Filing Date: 18/Mar/2009

Abstract:

The invention relates to hyper-branched polymers having a hydrophobic core and an antimicrobial and/or anti-adhesive active shell for providing surfaces with semi-permanent hygienic characteristics.

Priority: DE200610046073 Applic. Date: 2006-09-27; WO2007EP60133 Applic. Date: 2007-09-25

Inventor: WEIDE MIRKO [DE]; DOERING STEVE [DE]; BREVES ROLAND [DE]; SCHLOESSER ANJA [DE]; TILLER JOERG [DE]; FUCHS ANDREAS [DE]


Application No.: US20090238897A1  Published: 24/Sep/2009

Title: REMOVAL OF SKIN CHANGES

Applicant/Assignee:

Application No.: 12/294017   Filing Date: 21/Mar/2006

Abstract:

The present invention relates to the field of skin disorders, particularly to the prevention and/or treatment of benignant or malignant changes of the epidermis visible in form of e.g. nevus. A pharmaceutical, dermatological and/or cosmetic composition is disclosed comprising as active constituent the boroxine compound. The present invention further provides the respective uses of the boroxine compound in medicine, particularly in the field of skin disorders, and in dermatological and/or cosmetic applications.

Priority: WO2006IB02033 Applic. Date: 2006-03-21

Inventor: GALIC BORIVOJ [BA]


Application No.: US20090238905A1  Published: 24/Sep/2009

Title: INFLAMMATION REDUCING ACTION OF SYNERGISTIC MIXTURES OF BISABOLOL AND GINGER EXTRACTS

Applicant/Assignee: SYMRISE, INC

Application No.: 12/407458   Filing Date: 19/Mar/2009

Abstract:

A formulation for treating or eliminating irritation and/or inflammation-reducing effect on endodermal tissue of the respiratory tract, the gastrointestinal tract, or both is disclosed. The formulation can include bisabolol or an extract containing bisabolol and actives found in ginger or extracted from ginger. The ratio of bisabolol and actives from ginger is adjusted such that the irritation and inflammation-reducing action of the bisabolol constituents and ginger constituents is increased synergistically.

Priority: US20080038248P Applic. Date: 2008-03-20

Inventor: GURNEY MARTIN [US]; ROSA DONNA [US]; KENNISON DEBORAH [US]; MANGOS THOMAS [US]


Application No.: US20090239913A1  Published: 24/Sep/2009

Title: Process for the treatment and prevention of diseases caused by fungi

Applicant/Assignee:

Application No.: 12/378323   Filing Date: 17/Feb/2009

Abstract:

The subject invention is directed to the treatment of infections caused by fungi which are resistant to standard antifungal drugs such as fluconazole. The treatment method involves administering to the sufferer an effective amount of an agent that suppresses the activity of the fungal (H+)-ATPase pump (Pma1p). Such agents may take the form of: a) 2-phenyl-1,2-benzisoselenazol-3(2H)-one, commonly referred to as ebselen and depicted by Formula I, or b) 2-phenyl-1,2-benzisoselenazol-3(2H)-one 1-oxide, commonly referred to as ebselen se-oxide and depicted by Formula II, or pharmaceutically acceptable salts thereof. Opportunistic fungal infections include those which are systemic and those which are superficial and are caused by species of fungi belonging to the genus Candida, Aspergillus, Pneumocystis, Tinea, Blastomyces, Cryptococcus, Histoplasma, Sporotrichum, Malassezia, Hansenula, Rhodotorula, Trichosporon, as well as others.

Priority: US20080065833P Applic. Date: 2008-02-19

Inventor: BILLACK BLASE CHRISTOPHER [US]; BILLACK ANETA MARTA [US]


Application No.: US20090239919A1  Published: 24/Sep/2009

Title: Glutamate receptor modulators and therapeutic agents

Applicant/Assignee:

Application No.: 12/381086   Filing Date: 06/Mar/2009

Abstract:

The present invention discloses methods of modulating the activity of Group I mGluRs using a defined class of benzamide compounds. In one embodiment, methods of modulating the activity of mGluR1 are provided. In another embodiment, methods of modulating the activity of mGluR5 are provided. In still another embodiment, methods of simultaneously modulating the activities of both mGluR1 and mGluR5 are provided. The present invention also provides methods of treating diseases or disorders which are mediated in full or in part by Group I mGluRs using one or more compounds belonging to the defined class of benzamide compounds. The present invention further provides methods of preventing diseases or disorders which are mediated in full or in part by Group I mGluRs using one or more compounds belonging to the defined class of compounds. Diseases and disorders contemplated include, inter alia, diseases and disorders of the central nervous system, the peripheral nervous system, the gastrointestinal system, the circulatory system, skin, retina, brain, heart, and lungs.

Priority: US20080068493P Applic. Date: 2008-03-08

Inventor: WOOD RICHARD DELAREY [US]; WELSH WILLIAM J [US]; EKINS SEAN [US]; AI NI [US]


Application No.: US20090239967A1  Published: 24/Sep/2009

Title: POLYMERIZABLE COMPOSITIONS WITH INITIATORS CONTAINING SEVERAL GE ATOMS

Applicant/Assignee: IVOCLAR VIVADENT AG

Application No.: 12/276030   Filing Date: 21/Nov/2008

Abstract:

Composition with at least one polymerizable binder and one polymerization initiator, which contains at least one acylgermanium compound according to general Formula (I), and the use of acylgermanes of Formula (I) as initiators for radical polymerization or for the preparation of dental restorations.

Priority: EP20080102841 Applic. Date: 2008-03-20

Inventor: MOSZNER NORBERT [LI]; ZEUNER FRANK [LI]; LISKA ROBERT [AT]; RHEINBERGER VOLKER M [LI]; LAMPARTH IRIS [CH]; FISCHER URS KARL [CH]


Application No.: US20090239969A1  Published: 24/Sep/2009

Title: DENTAL PROSTHETICS COMPRISING CURABLE ACRYLATE POLYMER COMPOSITIONS AND METHODS OF THEIR USE

Applicant/Assignee: SCIENTIFIC PHARMACEUTICALS, INC

Application No.: 12/476918   Filing Date: 02/Jun/2009

Abstract:

Disclosed herein are acrylic and methacrylic acid ester-based polymeric materials containing as flexibilizing and brittleness reducing agents 1-60% of C4-C8 polyalkylene or polyalkyldiene compounds, preferably having a molecular weight of 300-2100, and the use of such materials in dentistry and medicine.

Priority: US2004-914972 Applic. Date: 2004-08-10

Inventor: ORLOWSKI JAN A [US]; BUTLER DAVID V [US]; CHIN ALICE [US]


Application No.: US20090241262A1  Published: 01/Oct/2009

Title: Mobile veterinary surgical table incorporating a dental operatory

Applicant/Assignee:

Application No.: 12/383517   Filing Date: 25/Mar/2009

Abstract:

A mobile veterinary surgical table incorporating a dental operatory, the mobile veterinary surgical table having a base member having a mobility means, a support pedestal member mounted to the base frame member allowing height adjustment of the support surface of the veterinary surgical table, the veterinary surgical support being bifurcated so as to be angularly oriented from the horizontal to a V-shape, the veterinary support member being tiltable at a desired angle and having a runoff tray positioned beneath the support surface for the disposition of fluids, there being positioned at one end of the support surface a dental tray, there being positioned on the base frame beneath the support surface a dental operatory, including all of the tools required for the operation of the dental operatory for performing dental treatment of the animal while its head is positioned on the dental tray.

Priority: US20080072128P Applic. Date: 2008-03-28

Inventor: JEHN FRANK [US]


Application No.: US20090241983A1  Published: 01/Oct/2009

Title: Abrasive Dental Floss and Method of Making Same

Applicant/Assignee: COLTEC INDUSTRIES INC

Application No.: 12/057058   Filing Date: 27/Mar/2008

Abstract:

Polytetrafluoroethylene (PTFE) flosses have abrasives added to the floss fiber that increase the abrasion to teeth surfaces, and thus result in a floss that provides enhanced cleaning of surfaces of teeth that face interstices between teeth. Floss fiber is formed by loading a PTFE resin with an abrasive filler. The PTFE resin and filler are processed to form a floss fiber with a surface that provide enhanced abrasion properties.

Priority:

Inventor: WILLIAMS CHARLES T [US]; HILL KIMBERLY E [US]


Application No.: US20090241997A1  Published: 01/Oct/2009

Title: Removing Soluble Support Material From Rapid Prototype Part

Applicant/Assignee:

Application No.: 12/436053   Filing Date: 05/May/2009

Abstract:

A container has been devised for use with a rapid prototype part making machine, specifically of the type having Fused Deposition Modeling (FDM) capabilities. The container includes a liner that has an exterior surface and that is expandable to define a mouth portion and a volume for receiving, via the mouth portion, a rapid prototype part having soluble support material deposited on the rapid prototype part. An inlet port is formed on the exterior surface and is in fluid communication with the volume. An outlet port is formed on the exterior surface and is in fluid communication with the volume. A sealing arrangement is configured and arranged to selectively substantially prevent egress of an aqueous cleaning solution from the mouth portion of the liner. The inlet port is configured to introduce the aqueous cleaning solution into the volume to remove the soluble support material from the rapid prototype part.

Priority: US2004-991679 Applic. Date: 2004-11-18; US20030523776P Applic. Date: 2003-11-19

Inventor: TAFOYA DAVID JONATHAN [US]


Application No.: US20090242000A1  Published: 01/Oct/2009

Title: HAND HELD SELF CONTAINED PACIFIER OR BABY BOTTLE NIPPLE SPRAY CLEANER

Applicant/Assignee:

Application No.: 12/058410   Filing Date: 28/Mar/2008

Abstract:

A hand held self contained cleaning apparatus includes a reservoir containing a single use cleaning and/or disinfecting liquid, a pump, and a nozzle for directing a spray of the cleaning and/or disinfecting liquid against a soiled nipple of a pacifier or baby bottle cap. The apparatus includes a platform for supporting the pacifier or bottle cap, a mouth for inserting the nipple into an area just above the nozzle, and a separator for preventing dirty liquid from returning to the reservoir. The spray is directed against a soiled nipple to loosen and remove soil from the nipple. After cleaning the pacifier or bottle cap, the dirty cleaning liquid is released so new clean liquid may be used for the next cleaning. The apparatus may be carried with other related items and used to clean the pacifier or bottle cap at any location and in particular away from home.

Priority:

Inventor: JIMENEZ MATTHEW [CA]


Application No.: US20090242447A1  Published: 01/Oct/2009

Title: SMART EVIDENCE AND BAGGAGE SYSTEM

Applicant/Assignee:

Application No.: 12/411449   Filing Date: 26/Mar/2009

Abstract:

A closable bag for use in storing items removed from injured, ill, or deceased persons. The bag is suitably of flexible, plastic. The bag has a bag mouth area providing an opening to the bag, a detachable segment disposed in the mouth area and having an aperture and having a bar code number on an exterior surface of the detachable segment, a bag main portion having a recordation area on an exterior surface of the bag main portion and having a corresponding bar code number on an exterior surface of the bag main portion, a closure member in the bag main portion and near the bag mouth area, and a perforated tear strip disposed between the closure member and the opening to the bag mouth area. Also, a kit including a container for storing one or more of the bags. Also, a method for storing personal items, removed from injured and/or ill persons, or from deceased persons, in one or more of the bags.

Priority: US2006-344923 Applic. Date: 2006-02-01

Inventor: SMART COLIN [GB]; PENNELIS SIMON [GB]; PITTAWAY MARK [GB]


Application No.: US20090242504A1  Published: 01/Oct/2009

Title: Soft PET Bottle With a Rigid Top and Bottom Portion

Applicant/Assignee: AOKI TECHNICAL LABORATORY, INC

Application No.: 12/056363   Filing Date: 27/Mar/2008

Abstract:

Disclosed herein is a plastic bottle suitable for vending from vending machines and for storing food or beverage products having comparatively high viscosities. A bottle is provided with a mouth, a flexible main unit having a tubular body section in fluid communication with the mouth, a base forming a bottom of the main unit and configured to support the bottle to stand upright, and a rigid portion located above the main unit and having greater traverse strength than said main unit. The mouth, main unit, and base define a retention space with a central axis. The rigid portion includes regions facing each other across from the central axis at the most distant position from the central axis. Moreover, the tubular body section of the main unit deforms into a substantially flat shape when an external force is applied in a transverse direction without the rigid portion undergoing plastic deformation.

Priority:

Inventor: KUBOI SATOSHI [JP]; TAKEUCHI HIDEKI [JP]


Application No.: US20090242771A1  Published: 01/Oct/2009

Title: Non-invasive qualitative measurement of chemistry of blood and bodily fluids

Applicant/Assignee:

Application No.: 12/157513   Filing Date: 11/Jun/2008

Abstract:

Mid-IR spectrometer with no moving parts, which is small and compact, low power consuming, and can monitor blood sugar (glucose) and other blood and bodily fluid analytes on a continuing basis. It has many applications in the health, forensic, environmental and other areas.

Priority: US20070933969P Applic. Date: 2007-06-11

Inventor: HARTLEY FRANK [US]


Application No.: US20090246150A1  Published: 01/Oct/2009

Title: ANTIMICROBIAL COMPOSITION

Applicant/Assignee:

Application No.: 10/596623   Filing Date: 06/Jun/2008

Abstract:

The present invention relates to novel antimicrobial composition comprising a peptide which can be obtained from the milk protein casein or chemically synthesised or produced by recombinant DNA technology and a divalent cation.

Priority: AU20030907002 Applic. Date: 2003-12-19; WO2004AU01764 Applic. Date: 2004-12-15

Inventor: REYNOLDS ERIC CHARLES [AU]; DASHPER STUART GEOFFREY [AU]; PAOLINI RITA ANN [AU]


Application No.: US20090246215A1  Published: 01/Oct/2009

Title: Amyloid beta1-6 antigen arrays

Applicant/Assignee: NOVARTIS PHARMA AG

Application No.: 11/905986   Filing Date: 05/Oct/2007

Abstract:

The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular an Abeta1-6 peptide-VLP-composition. More specifically, the invention provides a composition comprising a virus-like particle and at least one Abeta1-6 peptide bound thereto. The invention also provides a process for producing the conjugates and the ordered and repetitive arrays, respectively. The compositions of the invention are useful in the production of vaccines for the treatment of Alzheimer's disease and as a pharmaccine to prevent or cure Alzheimer's disease and to efficiently induce immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune responses within the indicated context.

Priority: US2003-622087 Applic. Date: 2003-07-18; US20030470432P Applic. Date: 2003-05-15; US20020396639P Applic. Date: 2002-07-19

Inventor: BACHMANN MARTIN F [CH]; TISSOT ALAIN [CH]; ORTMANN RAINER [FR]; LUOND RAINER [CH]; STAUFENBIEL MATTHIAS [DE]; FREY PETER [CH]


Application No.: US20090246303A1  Published: 01/Oct/2009

Title: Method for Reducing The Effects of Chemotherapy Using Flagellin Related Polypeptides

Applicant/Assignee:

Application No.: 12/369704   Filing Date: 11/Feb/2009

Abstract:

The use of flagellin and flagellin related polypeptides for reducing cancer treatment side effects in mammals is described.

Priority: US20080027729P Applic. Date: 2008-02-11

Inventor: GUDKOV ANDREI V [US]; KRIVOKRYSENKO VADIM [US]; BURDELYA LYUDMILA [US]


Application No.: US20090246724A1  Published: 01/Oct/2009

Title: RESTORATIVE DENTAL APPLIANCES

Applicant/Assignee:

Application No.: 12/055010   Filing Date: 25/Mar/2008

Abstract:

A dental appliance is described herein. In one embodiment, the dental appliance comprises a concave trough conforming to a plurality of teeth when placed over the plurality of teeth. The concave trough is configured to transition from a first shape to a second shape if a deforming force is applied. The concave trough comprises a shape memory material. The shape memory material is configured to restore the concave trough to an approximate first shape upon an application of an external stimulus. The first shape is configured to apply a first force on a tooth when the trough conforms.

Priority:

Inventor: CHEN YAN [US]; LI CHUNHUA [US]


Application No.: US20090246735A1  Published: 01/Oct/2009

Title: PROCESS FOR PRODUCING COLOURED SINTERED CERAMIC BODIES, IN PARTICULAR FOR DENTAL APPLICATIONS

Applicant/Assignee:

Application No.: 12/377396   Filing Date: 24/Aug/2007

Abstract:

Coloring materials are added in dry powder form to the material of the base composition to form a colored ceramic body.

Priority: DE200610039859 Applic. Date: 2006-08-25; WO2007EP58802 Applic. Date: 2007-08-24

Inventor: ROGOWSKI DIRK [DE]; SPRUEGEL TANJA [DE]; ESCHLE MATTHIAS [DE]


Application No.: US20090246823A1  Published: 01/Oct/2009

Title: EVALUATION METHODOLOGY OF THE PROTECTION CHARACTERISTICS OF PERSONAL PROTECTIVE EQUIPMENTS AGAINST BIOLOGICAL AGENTS

Applicant/Assignee: CL.COM S.R.L

Application No.: 12/297109   Filing Date: 03/Apr/2007

Abstract:

New testing methodology for the evaluation of the protection of the Personal Protective Equipments (PPE) for the respiratory tract against biological agents, characterized in that different machineries are used to reproduce the usage of the PPE, simulating a breathing through the Sheffield's head and self-respirator. The apparatus consists of: a) a viral and/or bacterial aerosol generator b) a test chamber containing the Sheffield's head c) a respirator simulating breathing and adjusting the inspiration and expiration frequency d) a suction system delivering the samples of air withdrawn in different points to the bubblers to determine the viral and/or bacterial concentrations.

Priority: IT2006PS00008 Applic. Date: 2006-04-12; WO2007IT00250 Applic. Date: 2007-04-03

Inventor: CERBINI STEFANO [IT]


Application No.: US20090247567A1  Published: 01/Oct/2009

Title: BENZOPYRAN AND BENZOXEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE

Applicant/Assignee: GENENTECH, INC

Application No.: 12/414403   Filing Date: 30/Mar/2009

Abstract:

Benzopyran and benzoxepin compounds of Formulas I and II, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including p110 alpha and other isoforms of PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formulas I and II for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Priority: US20080040827P Applic. Date: 2008-03-31; US20080102220P Applic. Date: 2008-10-02

Inventor: DO STEVEN [US]; GOLDSMITH RICHARD [US]; HEFFRON TIM [US]; KOLESNIKOV ALEKSANDR [US]; STABEN STEVEN [US]; OLIVERO ALAN G [US]; SIU MICHAEL [US]; SUTHERLIN DANIEL P [US]; ZHU BING-YAN [US]; GOLDSMITH PAUL [CH]; BAYLISS TRACY [CH]; FOLKES ADRIAN [CH]; PEGG NEIL [CH]


Application No.: US20090247580A1  Published: 01/Oct/2009

Title: NITROXIDE RADIOPROTECTOR FORMULATIONS AND METHODS OF USE

Applicant/Assignee: MITOS PHARMACEUTICALS, INC

Application No.: 12/479620   Filing Date: 05/Jun/2009

Abstract:

Pharmaceutical compositions useful in preventing and treating negative side effects accompanying radiotherapy are disclosed. More particularly, new formulations that can be applied to the skin and mucous membranes of patients undergoing radiotherapy and methods of using these formulations are disclosed.

Priority: US2003-675225 Applic. Date: 2003-09-29; US20020429887P Applic. Date: 2002-11-26; US20020415089P Applic. Date: 2002-10-01

Inventor: MAXWELL KAMERON W [US]; HOYLE PETER C [US]


Application No.: US20090247626A1  Published: 01/Oct/2009

Title: Method of Treating Dyslipidemia Using Naturally Occurring Diterpene

Applicant/Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH

Application No.: 12/323156   Filing Date: 25/Nov/2008

Abstract:

A method for treatment and or/prevention of dyslipidemia is provided. The invention relates to reducing low density lipoprotein cholesterol concentration by using naturally occurring diterpene (16alpha-hydroxycleroda-3,13(14)Z-dien-15,16-olide, a compound having formula (1)) isolated from leaves of Polyalthia longifolia.

Priority: IN2008DE00773 Applic. Date: 2008-03-26

Inventor: SASHIDHARA KONENI VANKATA [IN]; PURI ANJU [IN]; ROSAIAH JAMMIKUNTLA NAGA [IN]


Application No.: US20090247660A1  Published: 01/Oct/2009

Title: NOVEL MONOMER FOR DENTAL COMPOSITIONS

Applicant/Assignee:

Application No.: 12/415180   Filing Date: 31/Mar/2009

Abstract:

A novel monomer, 1,1,1-tri-[4-(methacryloxyethylaminocarbonyloxy)-phenyl]ethane (MPE) can be used in preparing dental compositions The MPE monomer can be combined into a dental adhesive with hydroxyethyl methacrylate (HEMA) and BisGMA (bisphenol A dimethacrylate). The MPE polymer can be polymerized with a photoinitiator system, such as a system that includes an iodonium salt. The iodonium salt can be diphenyliodonium hexafluorophosphate.

Priority: US20080041401P Applic. Date: 2008-04-01

Inventor: PARK JONGGU [US]; SPENCER PAULETTE [US]; TOPP ELIZABETH MURPHY [US]; YE QIANG [US]


Application No.: US20090247665A1  Published: 01/Oct/2009

Title: FILLER CONTAINING COMPOSITION AND PROCESS FOR PRODUCTION AND USE THEREOF

Applicant/Assignee:

Application No.: 12/298347   Filing Date: 26/Apr/2007

Abstract:

The invention relates to a composition comprising an ethylenically unsaturated acidic compound, water, a functionalized silane, an initiator, optionally comprising a sensitising agent, a non-surface treated filler, optionally a solvent, optionally an ethylenically unsaturated compound, optionally additives selected from the group consisting of stabilizer(s), photobleachable colorant(s), fluoride release agent(s), pigments. The invention also relates to a process of producing such a composition by in-situ silanization of the non-surface treated filler.

Priority: EP20060008643 Applic. Date: 2006-04-26; WO2007US67476 Applic. Date: 2007-04-26

Inventor: THALACKER CHRISTOPH [DE]; HEUMANN ANDREAS A [DE]


Application No.: US20090247715A1  Published: 01/Oct/2009

Title: Radical polymerizable macrocyclic resin compositions with low polymerization stress

Applicant/Assignee:

Application No.: 12/381860   Filing Date: 17/Mar/2009

Abstract:

A composition of macrocyclic oligomer with at least one polymerizable group, (meth)acrylate, for example.

Priority: US2008-079987 Applic. Date: 2008-03-31; US2005-153089 Applic. Date: 2005-06-15; US20040579837P Applic. Date: 2004-06-15

Inventor: JIN XIAOMING [US]; HAMMESFAHR PAUL D [US]


Application No.: US20090249572A1  Published: 08/Oct/2009

Title: Cleaning Tool Assembly With A Disposable Cleaning Implement

Applicant/Assignee:

Application No.: 12/062200   Filing Date: 03/Apr/2008

Abstract:

A cleaning assembly including a disposable cleaning implement having a cleaning element mounted to a fitment having an elongated post. The cleaning assembly includes an elongated maneuvering wand having a handle portion and a distal implement attachment end thereof. A gripping mechanism is coupled to the wand attachment end, and is configured to releasably grip the fitment post to mount the cleaning implement. The gripping mechanism and the maneuvering wand cooperate to substantially limited pivotal movement of a longitudinal axis of the fitment post, relative a longitudinal axis of the gripping mechanism to not more than about 0 degrees to about 25 degrees when the fitment post is subjected to forces radial to the longitudinal axis of the fitment post. In another aspect, the frictional drag between the sliding components is significantly reduced, enabling a tool assembly with a high axial holding force for the cleaning implement, but with a significantly lower, consumer friendly release force for the implement during release operation of the tool assembly.

Priority:

Inventor: MINKLER DOUGLAS J [US]; BELL RUSSELL E [US]


Application No.: US20090252647A1  Published: 08/Oct/2009

Title: COMPOSITIONS AND METHODS FOR APPLYING ANTIMICROBIALS TO SUBSTRATES

Applicant/Assignee: CROSSTEX INTERNATIONAL, INC

Application No.: 12/061128   Filing Date: 02/Apr/2008

Abstract:

Methods and compositions are provided that control spread of pathogens and prevent infections. In various embodiments, a liquid impervious substrate having an antimicrobial disposed thereon is provided. In one embodiment, a method of antimicrobially treating a substrate is provided, comprising contacting the substrate with an effective amount of a water stable composition, comprising i) water

ii) a product that is formed by reacting in water: a) an organosilane of the formula Rn SiX4-n where n is an integer of from 0 to 3

each R is, independently, a nonhydrolyzable organic group

and each X is, independently, a hydrolyzable group, with b) a polyol containing at least three hydroxy groups, wherein all of the hydroxy groups are separated by at least three intervening atoms, wherein the polyol is not hydroxyethyl cellulose, wherein the product is a monomer, oligomer, or a combination thereof, and iii) a wetting agent in an amount of 0.01% w/w or w/v to 10% w/w or w/v based on the weight of the total composition for a period of time sufficient to antimicrobially treat the substrate. In various embodiments, the substrate is a face mask or dental product.

Priority:

Inventor: OROFINO RICHARD ALLEN [US]


Application No.: US20090252817A1  Published: 08/Oct/2009

Title: Methods for the treatment or prevention of Diabetes Mellitus and other metabolic imbalances

Applicant/Assignee: BRANDEIS UNIVERSITY MALAYSIAN PALM OIL BOARD

Application No.: 12/080361   Filing Date: 02/Apr/2008

Abstract:

The invention relates to methods for treatment and prevention of a metabolic imbalance, including diabetes mellitus and other related diseases or disorders, using an extract from a fruit of genus Elaeis.

Priority:

Inventor: HAYES KENNETH C [US]; SUNDRAM KALYANA [MY]; SAMBANTHAMURTHI RAVIGADEVI [MY]; TAN YEW AI [MY]


Application No.: US20090253096A1  Published: 08/Oct/2009

Title: Dental filing tool

Applicant/Assignee:

Application No.: 12/284087   Filing Date: 17/Sep/2008

Abstract:

A dental filing tool includes a handle and a filing strip, wherein the handle includes first and second handle parts, each having a bridge and corresponding first and second arms extending therefrom, the handle parts connectable by a plurality of snap fittings and forming finger pads at either end when snapped together. Male snap fittings may include one or more cross-slots extending at least part of the length of the male snap fitting. A filing strip includes abrasive material on one or both faces, or a sharp-edged perforation pattern, and one or more serrated edges. The interior surfaces of the handle may be beveled to improve comfort and better fit between teeth. The bridge portion of the handle parts can include a raised portion and indicia formed into or printed on the raised portion.

Priority: US2006-401538 Applic. Date: 2006-04-10; US2004-945033 Applic. Date: 2004-09-21; US2007-982117 Applic. Date: 2007-11-01; US2005-271291 Applic. Date: 2005-11-12

Inventor: KIM DANIEL S [US]


Application No.: US20090253101A1  Published: 08/Oct/2009

Title: ORAL HYGIENE COMPOSITION AND APPARATUS AND METHOD

Applicant/Assignee:

Application No.: 12/061493   Filing Date: 02/Apr/2008

Abstract:

A method and accompanying apparatus that allows high concentrations of hydrogen peroxide for tooth whitening by use of an aerosol spray. The aerosol spray may be delivered through a mouthpiece that will direct the spray onto the teeth while inhibiting any escape of the spray to the lips and outside the moth. Also, in combination with antiplaque formulations, enhanced tooth whitening is effected.

Priority:

Inventor: ARNOLD MICHAEL [US]


Application No.: US20090253699A1  Published: 08/Oct/2009

Title: Compounds for Nonsense Suppression, and Methods for Their Use

Applicant/Assignee: PCT THERAPEUTICS, INC

Application No.: 11/577191   Filing Date: 13/Oct/2005

Abstract:

The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.

Priority: US20040617653P Applic. Date: 2004-10-13; US20040617670P Applic. Date: 2004-10-13; US20040617633P Applic. Date: 2004-10-13; US20040617634P Applic. Date: 2004-10-13; US20040617655P Applic. Date: 2004-10-13; US20040624170P Applic. Date: 2004-11-03; WO2005US36673 Applic. Date: 2005-10-13

Inventor: ALMSTEAD NEIL G [US]; CHEN GUANGMING [US]; KARP GARY M [US]; WELCH ELLEN [US]; WILDE RICHARD [US]; CAMPBELL JEFFREY A [US]


Application No.: US20090253795A1  Published: 08/Oct/2009

Title: Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibiton of pain and inflammation

Applicant/Assignee: OMEROS CORPORATION

Application No.: 12/384781   Filing Date: 08/Apr/2009

Abstract:

A method and solution for perioperatively inhibiting a variety of pain and inflammation processes during arthroscopic procedures. The solution preferably includes a vasoconstrictor that demonstrates substantial agonist activity at alpha adrenergic receptors and that is selected for peripheral (local) vasoconstriction and one or more additional pain and inflammation inhibitory agents at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. The solution is applied by continuous irrigation of a wound during a surgical procedure for peripheral vasoconstriction and inhibition of pain and/or inflammation while avoiding undesirable side effects associated with systemic application of larger doses of the agents.

Priority: US2002-138193 Applic. Date: 2002-05-01; US2001-839633 Applic. Date: 2001-04-20; WO1999US24672 Applic. Date: 1999-10-20; US19980105029P Applic. Date: 1998-10-20

Inventor: DEMOPULOS GREGORY A [US]; PIERCE PALMER PAMELA [US]; HERZ JEFFREY M [US]


Application No.: US20090253804A1  Published: 08/Oct/2009

Title: METHOD FOR TREATING OR PREVENTING DRY EYE DISORDERS USING ALKYLAMINO-POLYHYDROXYALKANES

Applicant/Assignee:

Application No.: 12/420374   Filing Date: 08/Apr/2009

Abstract:

Method for the treatment or prophylaxis of dry eye disorders by the administration of alkylamino-polyhydroxyalkanes and compositions thereof.

Priority: US20080043162P Applic. Date: 2008-04-08

Inventor: MARCY ALICE [US]; TOBIA ANNETTE M [US]


Application No.: US20090253908A1  Published: 08/Oct/2009

Title: NOVEL M3 MUSCARINIC ACETYLCHOINE RECEPTOR ANTAGONISTS

Applicant/Assignee: GLAXO GROUP LIMITED

Application No.: 10/598743   Filing Date: 11/Mar/2005

Abstract:

Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.

Priority: US20040552106P Applic. Date: 2004-03-11; WO2005US08302 Applic. Date: 2005-03-11

Inventor: BUDZIK BRIAN W [US]; COOPER ANTHONY W J [GB]; CORBETT DAVID FRANCIS [GB]; JIN JIAN [US]; LAINE DRAMANE I [US]; WANG YONGHUI [US]; MOORE MICHAEL LEE [US]; RIVERO RALPH A [US]; SHI DONGCHUAN [US]; WANG FENG [US]; XIE HAIBO [US]; ZHU CHONGJIE [US]


Application No.: US20090255535A1  Published: 15/Oct/2009

Title: DROPLET COLLECTION DEVICES AND METHODS TO DETECT AND CONTROL AIRBORNE COMMUNICABLE DISEASES UTILIZING RFID

Applicant/Assignee:

Application No.: 12/486679   Filing Date: 17/Jun/2009

Abstract:

A filtering face mask that comprises: (a) a mask body

and (b) at least one diagnostic device for identifying whether the wearer of the mask is infected with a contagious disease.

Priority: US2007-627329 Applic. Date: 2007-01-25; US20060762201P Applic. Date: 2006-01-25

Inventor: KANZER STEVE H [US]


Application No.: US20090255554A1  Published: 15/Oct/2009

Title: THREE DIMENSIONAL FACE MASK AND METHOD OF MANUFACTURE THEREOF

Applicant/Assignee:

Application No.: 12/421720   Filing Date: 10/Apr/2009

Abstract:

This face mask includes a right side sheet and a left side sheet which are mutually enantiomorphic. On a right side sheet and a left side sheet, a thermoplastic adhesive material is applied to the inner sides of ranges which include front edge strip portions which, during use, oppose the median line of the user's face

the right side sheet and the left side sheet are then laid together overlapping their inner sides

and heat is applied to areas of these front edge portions other than portions which, during use, oppose the nostrils and the mouth of the user, so that thereby the right side sheet and the left side sheet are joined together. By then opening out the right side sheet and the left side sheet in the direction to separate them, this face mask is caused to assume a three dimensional shape over its entire surface.

Priority: JP20080105937 Applic. Date: 2008-04-15; JP20080210497 Applic. Date: 2008-08-19; JP20090067835 Applic. Date: 2009-03-19

Inventor: OMOTO SUSUMU [JP]


Application No.: US20090256108A1  Published: 15/Oct/2009

Title: CONDITIONING AGENT FOR ETCHING ENAMEL LESIONS

Applicant/Assignee: ERNST MUHLBAUER GMBH & CO. KG

Application No.: 12/422058   Filing Date: 10/Apr/2009

Abstract:

The invention relates to a composition which comprises a) 4 to 80% by weight of at least one acid which has a pKa of 2 or less

b) a protic solvent

the acid having a saturation vapor pressure at 20 DEG C. of 120 mbar or less, for use as conditioning agent for etching enamel lesions.

Priority: EP20080007195 Applic. Date: 2008-04-11; US20080045497P Applic. Date: 2008-04-16

Inventor: NEFFGEN STEPHAN [DE]; LEANDER SWEN [DE]; LUBBERS DIERK [DE]


Application No.: US20090256109A1  Published: 15/Oct/2009

Title: CONDITIONING AGENT FOR THE ETCHING OF ENAMEL LESIONS

Applicant/Assignee: ERNST MUHLBAUER GMBH & CO. KG CHARITE UNIVERSITATSMEDIZIN BERLIN

Application No.: 12/422063   Filing Date: 10/Apr/2009

Abstract:

The invention relates to a composition which comprises 1 to 80% by weight of at least one acid which has a pKa of 2 or less

a protic solvent

a complexing agent for Ca2+ ions

for use as conditioning agent for etching enamel lesions.

Priority: EP20080007196 Applic. Date: 2008-04-11; US20080045791P Applic. Date: 2008-04-17

Inventor: NEFFGEN STEPHAN [DE]; NEANDER SWEN [DE]; LUBBERS DIERK [DE]


Application No.: US20090256274A1  Published: 15/Oct/2009

Title: Lithium silicate glass ceramic and method for fabrication of dental appliances

Applicant/Assignee: JAMES R., GLIDEWELL DENTAL CERAMICS, INC

Application No.: 12/283472   Filing Date: 12/Sep/2008

Abstract:

The present invention relates to preparing an improved lithium silicate glass ceramic for the manufacture of blocks for dental appliance fabrication using a CAD/CAM process. The lithium silicate material has a chemical composition that is different from those reported in the prior art including 8 to 10% of germanium dioxide in the final composition. The softening points are close to the crystallization final temperature of 830 DEG C. indicating that the samples will support the temperature process without shape deformation. The resulting material has improved castability and higher density.

Priority: US2008-082576 Applic. Date: 2008-04-11

Inventor: CASTILLO RODOLFO [US]


Application No.: US20090257685A1  Published: 15/Oct/2009

Title: FLEXIBLE STORAGE BAG WITH VENT BETWEEN TWO ZIPPER

Applicant/Assignee: ILLINOIS TOOL WORKS INC

Application No.: 12/420195   Filing Date: 08/Apr/2009

Abstract:

A bag comprising a receptacle and first and second reclosable structures installed inside and across a mouth of the receptacle, the first and second reclosable structures being parallel and spaced apart from each other. At least portions of the first and second reclosable structures bound a passageway within the mouth of the receptacle when the first and second reclosable structures are in fully closed states. The receptacle comprises a vent that is in flow communication with an interior volume of the receptacle via the passageway when both the vent and the first reclosable structure are in at least partially open states. If, while the first and second reclosable structures are in fully closed states, the pressure inside the interior volume is increased sufficiently, the first reclosable structure will open at least partly to allow gas from the interior volume to escape into the passageway while the second reclosable structure remains in a fully closed state.

Priority: US20080044541P Applic. Date: 2008-04-14

Inventor: MATIAS VICTOR [US]


Application No.: US20090257961A1  Published: 15/Oct/2009

Title: DENTURE CARE COMPOSITION

Applicant/Assignee:

Application No.: 12/438841   Filing Date: 30/Aug/2007

Abstract:

This invention relates to a new denture care composition and method of use. In particular, this invention relates to a film-forming denture care composition that kills odor causing bacteria, maintains prolonged fresh breath for two or more hours and is an effective guard against denture odor.

Priority: US20060842202P Applic. Date: 2006-09-01; WO2007US77167 Applic. Date: 2007-08-30

Inventor: DENG FANG [US]; DULLEA CHARLES V [US]; LECH STANLEY J [US]


Application No.: US20090257962A1  Published: 15/Oct/2009

Title: Compositions for human dental care

Applicant/Assignee:

Application No.: 12/384981   Filing Date: 10/Apr/2009

Abstract:

Compositions of the invention are water-based formulas that contain natural ingredients which aid in reduction of bacteria in the mouth, thereby reducing plaque and the production of tartar, and in one aspect of the invention are formulated as potable dental water that may be consumed in place of regular consumption of other forms of water or liquid, and in another aspect of the invention are formulated as dentifrices, such as toothpaste.

Priority: US20080123615P Applic. Date: 2008-04-10

Inventor: ALBERT KAREN L [US]


Application No.: US20090258046A1  Published: 15/Oct/2009

Title: COMPOSITION, FORMULATIONS AND KIT FOR TREATMENT OF RESPIRATORY AND LUNG DISEASE WITH NON-GLUCOCORTICOID STEROIDS AND/OR UBIQUINONE AND A BRONCHODILATING AGENT

Applicant/Assignee:

Application No.: 12/430800   Filing Date: 27/Apr/2009

Abstract:

A pharmaceutical or veterinary composition, which comprises a first active agent selected from a non-glucocorticoid steroid or analogues, a ubiquinone, or salts thereof, and a second active agent comprising a bronchodilator. The composition is provided in various formulations and in the form of a kit. The products of this patent are applied to the prophylaxis and treatment of respiratory, lung and malignant diseases.

Priority: US2004-475689 Applic. Date: 2004-08-12; WO2002US12552 Applic. Date: 2002-04-22; US20010286139P Applic. Date: 2001-04-24

Inventor: NYCE JONATHAN W [US]


Application No.: US20090258070A1  Published: 15/Oct/2009

Title: Topical LFA-1 antagonists for use in localized treatment of immune related disorders

Applicant/Assignee:

Application No.: 12/386359   Filing Date: 15/Apr/2009

Abstract:

This invention provides specifically formulated LFA-1 antagonists or pharmaceutically acceptable salts thereof that are suitable for topical delivery. In particular, the LFA-1 antagonists are particularly well suited for localized treatment by having a rapid systemic clearance rate. The invention also encompasses methods of treatment and prevention of immune related disorders using the LFA-1 topical formulations of the present invention.

Priority: US20080045240P Applic. Date: 2008-04-15

Inventor: BURNIER JOHN [US]; GADEK THOMAS [US]


Application No.: US20090258108A1  Published: 15/Oct/2009

Title: FOOD PRODUCT WITH AN ENCAPSULATED LECITHIN MATERIAL

Applicant/Assignee:

Application No.: 12/376081   Filing Date: 25/Jul/2007

Abstract:

A composition includes a first component containing phospholipids and a second component encapsulating the first component. The composition includes between about 10% and about 80% by weight phospholipids. The composition may be used in chewing gum to provide a gum cud that does not adhere to concrete and does not dissolve in the mouth while chewing.

Priority: US20060834646P Applic. Date: 2006-07-31; WO2007US16834 Applic. Date: 2007-07-25

Inventor: SHEN CHUNGSEA A [US]; CASTRO ARMANDO J [US]; CATIZONE MICHAEL [US]; PADOVANI BRUNO [US]; BARKALOW DAVID G [US]; XIA XIAOHU [US]


Application No.: US20090258326A1  Published: 15/Oct/2009

Title: Siwak tooth cleaning instrument

Applicant/Assignee:

Application No.: 12/081025   Filing Date: 09/Apr/2008

Abstract:

The siwak tooth cleaning instrument provides a carrying, protecting and application instrument for a siwak stick, to be applied to the user's teeth for cleaning thereof. In some embodiments, the siwak tooth cleaning instrument includes a tubular housing with a siwak that may be selectively and adjustably raised and lowered to extend the siwak from the housing for cleaning one's teeth, and retracted within the housing for storage and transport, similar to a lipstick. In other embodiments, the siwak tooth cleaning instrument has tooth cleaning cartridges including a siwak that releasably engage the head portion of an elongated handle. A cover may be pivotally attached to the handle for covering the handle and attached cartridge, or a storage tube with replacement cartridges may be pivotally attached to the handle.

Priority:

Inventor: AL-SULAIMAN FALEH A [SA]; HAWWA MUHAMMAD A [SA]


Application No.: US20090258858A1  Published: 15/Oct/2009

Title: MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS

Applicant/Assignee:

Application No.: 11/578000   Filing Date: 28/Oct/2005

Abstract:

Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.

Priority: US20040623558P Applic. Date: 2004-10-29; WO2005US39209 Applic. Date: 2005-10-28

Inventor: BUSCH-PETERSEN JAKOB [US]; BOEHM JEFFREY CHARLES [US]; LI HUIJIE [US]; TAGGART JOHN J [US]; YAN HONG XING [US]


Application No.: US20090258961A1  Published: 15/Oct/2009

Title: STABLE, CATIONICALLY POLYMERIZABLE/CROSSLINKABLE DENTAL COMPOSITIONS

Applicant/Assignee: BLUESTAR SILICONES FRANCE SAS

Application No.: 12/400314   Filing Date: 09/Mar/2009

Abstract:

Stable, highly filled cationic dental compositions useful for the production of dental prostheses and dental restoration materials contain: (1) at least one compound which is reactive cationically when activated, advantageously at least one UV-and cationically reactive oxirane-functionalized silicone

(2) at least one dental filler, advantageously SiO2

(3) at least one organic polymer or copolymer dispersant having an amine index less than or equal to 100 mg of potassium hydroxide per gram of dispersant, advantageously a polyurethane/acrylate copolymer or alkylammonium salt thereof

(4) at least one cationic photoinitiator, advantageously iodonium borate

and (5) optionally, at least one photosensitizer.

Priority: FR20020008857 Applic. Date: 2002-07-12; WO2003FR02649 Applic. Date: 2003-09-05; US2004-933537 Applic. Date: 2004-09-03; US20030501022P Applic. Date: 2003-09-09

Inventor: FRANCES JEAN-MARC [FR]


Application No.: US20090258965A1  Published: 15/Oct/2009

Title: FIBER-REINFORCED COMPOSITES AND METHOD FOR THE MANUFACTURE THEREOF

Applicant/Assignee: STICK TECH OY

Application No.: 12/306673   Filing Date: 29/Jun/2007

Abstract:

The present invention relates to fiber-reinforced composites, particularly application-oriented composites useful in dental and medical applications/appliances, such as fiber reinforced dental composites, and to a method for the manufacture thereof. Particularly the invention concerns random glass fiber-reinforced restorative composite resins with semi-interpenetrating polymer network matrix and their use in dental applications like cavity fillings, core composites, provisional and semi-permanent crown and bridge composite, cements and adhesives.

Priority: FI20060005465 Applic. Date: 2006-06-30; FI20070005075 Applic. Date: 2007-02-05; WO2007FI50404 Applic. Date: 2007-06-29

Inventor: LASSILA LIPPO V J [FI]; VALLITTU PEKKA K [FI]; GAROUSHI SUFYAN [FI]; AIROLA KARRI [FI]


Application No.: US20090258966A1  Published: 15/Oct/2009

Title: Dental Composition

Applicant/Assignee: NIHON UNIVERSITY SUN MEDICAL CO., LTD

Application No.: 12/089334   Filing Date: 04/Oct/2006

Abstract:

An object of the present invention is to provide a dental composition having excellent adhesive effect and simultaneously not causing microleakage. A dental composition of a first embodiment of the present invention includes (A) an acidic-group containing polymerizable monomer, (B) a polymerizable monomer, (C) a filler comprising poly(meth)acrylate particles, (D) a calcium-containing material including tetracalcium phosphate (TTCP) and dicalcium phosphate (DCP), and (E) a polymerization initiator. The component (A) is contained at 16-70 parts by weight based on a total of 100 parts by weight of (A)+(B). The component (B) is contained at 84-30 parts by weight based on a total of 100 parts by weight of (A)+(B). The component (C) is contained at 0.2-297 parts by weight relative to a total of 100 parts by weight of (A)+(B). The component (D) is contained at 0.2-297 parts by weight relative to a total of 100 parts by weight of (A)+(B).

Priority: JP20050291378 Applic. Date: 2005-10-04; JP20050291379 Applic. Date: 2005-10-04; WO2006JP319896 Applic. Date: 2006-10-04

Inventor: HIRAYAMA SATOSHI [JP]; IKEMI TAKUJI [JP]; TSUCHIYA YASUFUMI [JP]; ORI TATSUYA [JP]; YAMAMOTO TAKASHI [JP]


Application No.: US20090260641A1  Published: 22/Oct/2009

Title: METHOD AND SYSTEM FOR VAPORIZATION OF A SUBSTANCE

Applicant/Assignee: PLOOM, INC., A DELAWARE CORPORATION

Application No.: 12/482376   Filing Date: 10/Jun/2009

Abstract:

A smoking device for generating and releasing smoking vapor free from contamination into the mouth of a user comprising a mouthpiece for providing vapor for inhalation to a user including a tubular casing containing a heater for heating a smoking substance at a substantially constant low temperature by regulating the flow of fuel by a thermal regulator and further having means for visual indication of the operation of the device.

Priority: US2006-485168 Applic. Date: 2006-07-11; US20050700105P Applic. Date: 2005-07-19

Inventor: MONSEES JAMES [US]; BOWEN ADAM [US]


Application No.: US20090260997A1  Published: 22/Oct/2009

Title: Single Use Packaging For Dental Impression Material

Applicant/Assignee: DUX INDUSTRIES, INC

Application No.: 12/104332   Filing Date: 16/Apr/2008

Abstract:

A package for containing a preset quantity of a dry powder material is marked on its exterior with instructions for opening the package for transfer of its contents to a mixing container and cutting instructions, which may be the same, such that when the cutting instructions are followed a measuring container is created which has an internal volume preset to hold no more than the required quantity of liquid to be mixed with the dry powder material to create a wet mixture with desired handling properties.

Priority:

Inventor: ROVELLI FRANK [US]


Application No.: US20090263336A1  Published: 22/Oct/2009

Title: NOVEL PYRAN DERIVATIVES AND THEIR PREPARATION

Applicant/Assignee: V. MANE FILS

Application No.: 12/427085   Filing Date: 21/Apr/2009

Abstract:

A process of preparing a compound of formula (I) wherein R represents a linear or branched C5 alkyl group, as well as the use of such compounds in a fragrant and/or flavouring composition.

Priority: US20080046873P Applic. Date: 2008-04-22

Inventor: MANE JEAN [FR]; PLESSIS CAROLINE [FR]; CHANOT JEAN-JACQUES [FR]


Application No.: US20090263337A1  Published: 22/Oct/2009

Title: DETERSIVE COMPOSITIONS CONTAINING HYDROPHOBIC BENEFIT AGENTS PRE-EMULSIFIED USING SUB-MICROMETER-SIZED INSOLUBLE CATIONIC PARTICLES

Applicant/Assignee: AMCOL INTERNATIONAL CORPORATION

Application No.: 12/492653   Filing Date: 26/Jun/2009

Abstract:

A cationic oil-in-water emulsion, for addition to detersive compositions, comprising hydrophilic cationic polymers, a surface-active, anionic polymer that is capable of adsorbing at an air-water interface or an oil-water interface and/or is oil-soluble, and a hydrophobic benefit agent in the oil phase made by adding the benefit agent to a hydrophobic liquid

thickening the oil phase with an organophillic smectite clay reacted at clay platelet surfaces to make the clay platelet surfaces hydrophobic while the edge surfaces of the clay remain hydrophilic, such that the organophillic smectite clay is adsorbed at an oil/water interface in the emulsion, and one of the hydrophilic, cationic polymers has a cationic nitrogen content of at least 6% by weight, that is incompatible with anionic surfactants, being insoluble in anionic-surfactant solutions containing an amount of 3% or higher of an anionic surfactant, and another hydrophilic cationic polymer has a cationic nitrogen content of at least 0.1% by weight and has a molecular weight of at least 600,000 Dalton.

Priority: US2006-331248 Applic. Date: 2006-01-12; US20050643430P Applic. Date: 2005-01-12

Inventor: SENGUPTA ASHOKE K [US]; LIN ILONA [US]; ST ONGE JASON [US]


Application No.: US20090263467A1  Published: 22/Oct/2009

Title: COMBINATION DRUG THERAPY USING ORALLY DISSOLVING FILM OR ORALLY DISINTEGRATING TABLET DOSAGE FORMS TO TREAT DRY MOUTH AILMENTS

Applicant/Assignee:

Application No.: 12/107039   Filing Date: 21/Apr/2008

Abstract:

A combination drug therapy can be administered to patients to treat xerostomia or dry mouth or Sjogren's syndrome in the form of orally dissolving film or orally disintegrating tablets. Some of the drugs could be synthetic origin and some drugs are obtained from natural sources.

Priority:

Inventor: JOSHI HEMANT NARAHAR [US]


Application No.: US20090263498A1  Published: 22/Oct/2009

Title: Pharmaceutical preparations for treating inflammatory diseases

Applicant/Assignee:

Application No.: 12/148724   Filing Date: 22/Apr/2008

Abstract:

The present invention refers to a pharmaceutical preparation for treating inflammatory diseases and microbial infections comprising a pharmaceutically effective amount of ozone and at least one monomeric amino acid having an oxidation-sensitive side chain, or at least one ozonized monomeric amino acid having an oxidation-sensitive side chain. Also described is the use of a preparation as described before for providing a medicament for treating inflammatory diseases, microbial infections and for immune modulation. The pharmaceutical preparation according to the invention is particularly useful in the treatment of oral inflammations.

Priority:

Inventor: HUTH KARIN CHRISTINE [DE]; BRAND KORBINIAN [DE]


Application No.: US20090263647A1  Published: 22/Oct/2009

Title: NANOCOMPOSITE DIELECTRIC COATINGS

Applicant/Assignee: THE CURATORS OF THE UNIVERSITY OF MISSOURI

Application No.: 12/410988   Filing Date: 25/Mar/2009

Abstract:

The present invention describes processes for coating substrates with a nanocomposite SiCON material. In addition, the present invention describes the dielectric nanocomposite coatings.

Priority: US20080039288P Applic. Date: 2008-03-25

Inventor: GANGOPADHYAY SHUBHRA [US]; HOSSAIN MARUF [US]; GANGAPADHYAY KESHAB [US]


Application No.: US20090263660A1  Published: 22/Oct/2009

Title: SURFACE-TREATED POWDER AND COSMETICS CONTAINING SAME

Applicant/Assignee: MIYOSHI KASEI, INC

Application No.: 11/995617   Filing Date: 21/Jun/2006

Abstract:

By coating the surface of a powder comprising a silicone resin and/or an organic powder with a specific hydrophilizing agent, such powder is hydrophilized. The hydrophilizing agent includes water-soluble polyoxyalkylene glycol derivatives. The organic powder is at least one selected from PMMA, nylon, polyester, polystyrene, cellulose, silicone elastomer powder, silicone rubber powder, benzoguanamine, styrenedivinylbenzene pinhole polymer, ethylene tetrafluoride, polyethylene powder, polypropylene powder, polyurethane powder, silk powder, metal soap powder, starch powder, N-acylated lysine, an organic pigment, and a composite of at least one of these organic powders described above with a metal oxide and/or a metal hydroxide. Such coated (treated) powder has extremely great dispersibility (ease of dispersion) and very good dispersion stability (long-term dispersion stability with lapse of time) in aqueous dispersion media, particularly under acidic and alkaline conditions, specifically at pH 3 through 13. Using the surface-treated powder, additionally, a dispersion with good dispersibility (ease of dispersion) and great dispersion stability, preferably for cosmetics can be provided. The use of the surface-treated powder, or the use of the dispersion can provide further a cosmetic excellent in dispersibility and dispersion stability and further in re-dispersibility and dispersion stability with lapse of time and smooth feeling as compared to the related art when selecting aqueous cosmetic as an agent form.

Priority: WO2005JP12928 Applic. Date: 2005-07-13; WO2006JP312388 Applic. Date: 2006-06-21

Inventor: TAKEUCHI YASUSHI [JP]; KUWAZURU SHINYA [JP]; HORINO MASAAKIRA [JP]


Application No.: US20090263774A1  Published: 22/Oct/2009

Title: Radiopaque Artificial Tooth

Applicant/Assignee: COLUMBIA DENTOFORM CORPORATION

Application No.: 12/414270   Filing Date: 30/Mar/2009

Abstract:

An artificial tooth is provided that mimic the essential features of natural a tooth for use in training dental professionals. The artificial tooth is a radiopaque artificial tooth that is capable of providing for anatomically correct contrast on a radiograph. The artificial tooth also mimics the hardness, debris characteristics, and anatomical features of a natural tooth. A dental training device is also provided that includes a support structure generally configured as a mouth or jaw that supports radiopaque artificial teeth.

Priority: US20080072136P Applic. Date: 2008-03-28

Inventor: PICHARDO PENELOPE [US]; LIBRACH PHILLIP [US]; LJUJKOVIC FIKRET [US]


Application No.: US20090264422A1  Published: 22/Oct/2009

Title: METHOD OF TREATING DISEASE STATES USING SUBSTITUTED PYRAZOLE COMPOUNDS

Applicant/Assignee:

Application No.: 12/494677   Filing Date: 30/Jun/2009

Abstract:

Disclosed are protein kinase inhibitors, compositions comprising such inhibitors, and methods of use thereof. More particularly, disclosed are inhibitors of Aurora A (Aurora-2) protein kinase. Also disclosed are methods of treating diseases associated with protein kinases, especially diseases associated with Aurora-2, such as cancer.

Priority: US2006-541484 Applic. Date: 2006-09-29; US20050722217P Applic. Date: 2005-09-30; US20050732340P Applic. Date: 2005-10-31; US20050733868P Applic. Date: 2005-11-04

Inventor: XIAO XIAO-YI [US]; PATEL DINISH V [US]; WARD JOHN S [US]; BRAY MARK R [CA]; AGOSTON GREGORY E [US]; TRESTON ANTHONY M [US]


Application No.: US20090264427A1  Published: 22/Oct/2009

Title: 3-Cyanoquinolines, Methods for Preparation and Use as Insulin-like Growth Factor Inhibitors

Applicant/Assignee: WYETH

Application No.: 12/423096   Filing Date: 14/Apr/2009

Abstract:

Imidazole-substituted 4-anilino-3-cyanoquinolines are described, which selectively inhibit IFGR kinase activity and are useful for treating disorders associated with IGFR kinases.

Priority: US20080045429P Applic. Date: 2008-04-16

Inventor: MAYER SCOTT CHRISTIAN [US]; MILLER LORI MICHELLE [US]


Application No.: US20090264454A1  Published: 22/Oct/2009

Title: COMBINED HYDROCODONE AND ANALGESIC FORMULATION AND METHOD

Applicant/Assignee:

Application No.: 12/104374   Filing Date: 16/Apr/2008

Abstract:

The present invention is directed to co-administration of hydrocodone and a second analgesic agent for the treatment of pain. A pharmaceutical composition suitable for the co-administration contains a therapeutically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and a therapeutically effective amount of at least one second analgesic agent. A ratio of the hydrocodone or pharmaceutically acceptable salt thereof to the at least one second analgesic agent in the composition is within a range that provides greater pain relief than that obtainable by the administration of the hydrocodone or second analgesic agent alone. Examples of pharmaceutical compositions for co-administration of the agents are those containing hydrocodone and indomethacin ("Indocodone"), hydrocodone and naproxen ("Naprocodone"), hydrocodone and diclofenac ("Diclodone") and hydrocodone and tramadol ("Tramacodone").

Priority:

Inventor: NICKELL ROBERT P [US]


Application No.: US20090264465A1  Published: 22/Oct/2009

Title: CRYSTALLINE FORMS OF 4- [2- (4-METHYLPHENYLSULFANYL) -PHENYL] PIPERIDINE WITH COMBINED SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITION FOR THE TREATMENT OF NEUROPATHIC PAIN

Applicant/Assignee: H. LUNDBECK A/S

Application No.: 12/303449   Filing Date: 15/Jun/2007

Abstract:

Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine and salts thereof are provided e.g. for the treatment of neuropathic pain.

Priority: DK20060000816 Applic. Date: 2006-06-16; DK20070000423 Applic. Date: 2007-03-20; US20060805009P Applic. Date: 2006-06-16; WO2007DK50076 Applic. Date: 2007-06-15

Inventor: BANG-ANDERSEN BENNY [DK]; FALDT ANDRE [DK]; STENSBOL TINE BRYAN [DK]; MILLER SILKE [US]; DE DIEGO HEIDI LOPEZ [DK]


Application No.: US20090264474A1  Published: 22/Oct/2009

Title: SULFONAMIDES AS TRPM8 MODULATORS

Applicant/Assignee:

Application No.: 12/175740   Filing Date: 18/Jul/2008

Abstract:

Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: wherein A, B, G, Y, R1, R2, R3, and R4 are defined herein.

Priority: US20070950456P Applic. Date: 2007-07-18

Inventor: BRANUM SHAWN T [US]; COLBURN RAYMOND W [US]; DAX SCOTT L [US]; FLORES CHRISTOPHER M [US]; JETTER MICHELE C [US]; LIU YI [US]; LUDOVICI DONALD [US]; MACIELAG MARK J [US]; MATTHEWS JAY M [US]; MCNALLY JAMES J [US]; REANEY LAURA M [US]; RUSSELL RONALD K [US]; QIN NING [US]; TELEHA CHRISTOPHER [US]; WELLS KENNETH M [US]; YOUELLS SCOTT C [US]; YOUNGMAN MARK A [US]


Application No.: US20090264480A1  Published: 22/Oct/2009

Title: TRPA1 ANTAGONISTS

Applicant/Assignee: ABBOTT LABORATORIES

Application No.: 12/348065   Filing Date: 02/Jan/2009

Abstract:

Compounds of formula (I) wherein R1, R2, R3, and Y are defined in the description are TRPA1 antagonists. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

Priority: US20080019030P Applic. Date: 2008-01-04

Inventor: PERNER RICHARD J [US]; KORT MICHAEL E [US]; DIDOMENICO STANLEY [US]; CHEN JUN [US]; VASUDEVAN ANIL [US]


Application No.: US20090264500A1  Published: 22/Oct/2009

Title: 3-SUBSTITUTED-1,5-DIARLY-2-ALKYL-PYRROLES HIGHLY SELECTIVE AND ORALLY EFFECTIVE COX-2 INHIBITORS

Applicant/Assignee:

Application No.: 12/375650   Filing Date: 06/May/2009

Abstract:

This invention relates to 3-substituted-1,5-diaryl-2-alkyl-pyrroles of Formula I, pharmaceutical compositions containing them, and to their use for the pharmacological treatment of pain and COX-2 over-activation associated disorders. Compounds of this invention are new pyrrole derivatives bearing in position-3 of the pyrrole ring, several variously functionalized, not aliphatic, side chains which confer to the compounds a relevant COX-2 potency and selectivity along with a remarkable oral efficacy. Phenyl rings in position-1 and -5 are variously substituted, but compounds of particular interest are those substituted in position-5 with 4-methylsulphonyl-phenyl or with 4-aminosulphonyl-phenyl groups.

Priority: WO2006EP65011 Applic. Date: 2006-08-03

Inventor: CAPPELLI ANDREA [IT]; ANZINI MAURIZIO [IT]; BIAVA MARIANGELA [IT]; MAKOVEC FRANCESCO [IT]; GIORDANI ANTONIO [IT]; CASELLI GIANFRANCO [IT]; ROVATI LUCIO CLAUDIO [IT]


Application No.: US20090264509A1  Published: 22/Oct/2009

Title: Adenoviral vector-based foot-and-mouth disease vaccine

Applicant/Assignee: GENVEC, INC

Application No.: 12/117513   Filing Date: 08/May/2008

Abstract:

The invention is directed to an adenoviral vector comprising at least one nucleic acid sequence encoding an aphthovirus antigen and/or a cytokine operably linked to a promoter. The adenoviral vector is replication-deficient and requires at most complementation of both the E1 region and the E4 region of the adenoviral genome for propagation. The invention also is directed to a method of inducing an immune response in a mammal comprising administering to the mammal a composition comprising the aforementioned adenoviral vector.

Priority: WO2006US60830 Applic. Date: 2006-11-13; US20050735439P Applic. Date: 2005-11-10

Inventor: BROUGH DOUGLAS E [US]; BRUDER JOSEPH T [US]; KING C RICHTER [US]


Application No.: US20090264520A1  Published: 22/Oct/2009

Title: LIPID-CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF

Applicant/Assignee: ASHA LIPID SCIENCES, INC

Application No.: 12/426034   Filing Date: 17/Apr/2009

Abstract:

Lipid compositions comprising nuts, seeds, oils, legumes, fruits, grains, and dairy useful in specified amounts as dietary supplements and diet plans designed around and including the aforementioned for the prophylaxis and treatment of numerous diseases are disclosed. The compositions include omega-6 and omega-3 fatty acids where the ratio of the omega-6 to the omega-3 fatty acids and their amounts are controlled based on one or more factors including age of the subject, sex of the subject, diet of the subject, the body weight of the subject, medical conditions of the subject, and climate of the subject's living area.

Priority: US20080046747P Applic. Date: 2008-04-21; US20080075708P Applic. Date: 2008-06-25; US20080111593P Applic. Date: 2008-11-05

Inventor: BHAGAT URVASHI [US]


Application No.: US20090264530A1  Published: 22/Oct/2009

Title: COMBINED NSAID AND ACETAMINOPHEN FORMULATION AND METHOD

Applicant/Assignee:

Application No.: 12/104372   Filing Date: 16/Apr/2008

Abstract:

The present invention is directed to co-administration of a non-steroidal anti-inflammatory agent (NSAID) and acetaminophen for the treatment of pain and inflammation with reduced gastrointestinal irritation. A pharmaceutical composition suitable for the co-administration contains a therapeutically effective amount of at least one non-steroidal anti-inflammatory agent, and a therapeutically effective amount of acetaminophen or a pharmaceutically acceptable salt thereof. A ratio of the non-steroidal anti-inflammatory agent to acetaminophen in the composition is within a range that provides greater pain relief and reduction of inflammation with less gastrointestinal irritation than that obtainable by the administration of the non-steroidal anti-inflammatory agent or acetaminophen alone. Examples of pharmaceutical compositions for co-administration of the agents are those containing ibuprofen in combination with the acetaminophen.

Priority:

Inventor: NICKELL ROBERT P [US]


Application No.: US20090264836A1  Published: 22/Oct/2009

Title: Disposable Article Including A Nanostructure Forming Material

Applicant/Assignee:

Application No.: 12/369128   Filing Date: 11/Feb/2009

Abstract:

A disposable treatment article or disposable cleaning article that includes a hydrophobic nanoporous material. The disposable treatment or cleaning article is configured to contact and apply the nanoporous material to a surface. The nanoporous material is configured to form hydrophobic nanostructures on a surface upon the application of an activation stimulus. The nanostructures provide an anti-contamination benefit to the surface upon which the nanostructures are disposed.

Priority: US20080046891P Applic. Date: 2008-04-22

Inventor: ROE DONALD CARROLL [US]; SALLOUM DAVID S [US]; WISE BRANDON ELLIS [US]; GARTSTEIN VLADIMIR [US]; SHERMAN FAIZ FIESAL [US]


Application No.: US20090269367A1  Published: 29/Oct/2009

Title: METHODS AND COMPOUNDS FOR MITIGATING PATHOGENIC OUTBREAKS USING REPLIKIN COUNT CYCLES

Applicant/Assignee:

Application No.: 12/429044   Filing Date: 23/Apr/2009

Abstract:

The present invention provides methods of predicting increases in pathogenic virulence, morbidity, and/or mortality or expansion in pathogen populations within regions or into new regions by identifying cycles or ratios of increasing concentrations of a family of small peptides expressed in pathogens and provides compounds comprising the small peptides for treatment and prevention of pathogenic outbreaks.

Priority: WO2008US61336 Applic. Date: 2008-04-23; US2008-108458 Applic. Date: 2008-04-23; US20080054010P Applic. Date: 2008-05-16; US20080087354P Applic. Date: 2008-08-08; US20090143618P Applic. Date: 2009-01-09

Inventor: BOGOCH SAMUEL [US]; BOGOCH ELENORE S [US]; BOGOCH SAMUEL WINSTON [US]; BORSANYI ANNE ELENORE [US]


Application No.: US20090269720A1  Published: 29/Oct/2009

Title: Whitening Mouth Piece Device

Applicant/Assignee:

Application No.: 12/109312   Filing Date: 24/Apr/2008

Abstract:

A silicone mouthpiece insert for allowing a wearer to whiten their teeth while under a whitening lamp and can be used to hold whitening trays and allow light curing of whitening chemicals for the teeth. The device can also hold whitening sponges, whitening strips and chemicals directly placed in the holder or be used as a one piece whitening tray for both upper and lower teeth all at once allowing for molding of those tray all at once. It also holds open the upper and lower lip to keep the teeth exposed to the lights shining into the center and sides of the mouth to reach the upper and lower, right and left sides of the surface of the teeth.

Priority:

Inventor: O'DONNELL RICHARD [US]


Application No.: US20090269723A1  Published: 29/Oct/2009

Title: Methods for preparing chair-side dental crowns

Applicant/Assignee:

Application No.: 12/319543   Filing Date: 08/Jan/2009

Abstract:

The invention provides a method of forming dental restorations, particularly dental crowns. The method involves applying a flexible spacer material having a polymerization system capable of being activated by light to a prepared tooth surface. A composite crown-forming material is dispensed into a transparent plastic matrix. The matrix is placed in the mouth of the patient so the composite material is molded over the tooth surface coated with the spacer material. Then, the composite is irradiated with curing light, through the matrix, so that it hardens to form a dental crown. The crown is removed, trimmed and finished, and then permanently affixed to the tooth.

Priority: US2006-502139 Applic. Date: 2006-08-10; US20050706882P Applic. Date: 2005-08-10

Inventor: DIAS WALTER R [US]; SUN FUMING [US]; HARE ROBERT V [US]


Application No.: US20090270363A1  Published: 29/Oct/2009

Title: 2-Aryl- and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof

Applicant/Assignee: WYETH

Application No.: 12/412506   Filing Date: 27/Mar/2009

Abstract:

The present invention discloses fused bicyclic 2-aryl- or 2-heteroarylthiazolyl compounds and their pharmaceutically acceptable salts and esters thereof, which are useful for inhibiting the growth of cancerous cells, inhibiting human breast carcinoma tumor growth in particular and to treat diseases or disorders associated with securin, including elevated securin levels.

Priority: US20080039893P Applic. Date: 2008-03-27

Inventor: ZHANG NAN [US]; AYRAL-KALOUSTIAN SEMIRAMIS [US]; MANSOUR TAREK SUHAYL [US]; NGUYEN THAI HIEP [US]; NIU CHUANSHENG [US]; ROSFJORD EDWARD CHRISTIAN [US]; SUAYAN RONALD [US]; TSOU HWEI-RU [US]


Application No.: US20090270418A1  Published: 29/Oct/2009

Title: PYRAZOLE PYRAZINE AMINE COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS THEREOF AND METHODS OF TREATMENT THEREWITH

Applicant/Assignee:

Application No.: 12/350722   Filing Date: 08/Jan/2009

Abstract:

Provided herein are Pyrazole Pyrazine Amine Compounds having the following structure: Wherein Q and R1-R3 are as defined herein, compositions comprising an effective amount of a Pyrazole Pyrazine Amine Compound and methods for treating or preventing inflammatory conditions, immunological conditions, cancer, neurodegenerative diseases, age-related diseases, cardiovascular diseases and metabolic conditions, or conditions treatable or preventable by inhibition of an IKK, or an IKK pathway, comprising administering an effective amount of a Pyrazole Pyrazine Amine Compound to a patient in need thereof.

Priority: US20080010866P Applic. Date: 2008-01-09

Inventor: SLOSS MARIANNE [US]; MCKENNA JEFFREY [GB]; YOON WON HYUNG [US]; NORRIS STEPHEN [US]; ROBINSON DALE [US]; PARNES JASON [US]; SHEVLIN GRAZIELLA [US]; ERDMAN PAUL [US]; HILGRAF ROBERT [US]; ALBERS RONALD [US]; HEGDE SAYEE [US]; WALLACE ANDREW [US]; CHAN HENRY [US]; MADAKAMUTIL LOUI [US]; RAYMON HEATHER [US]


Application No.: US20090270447A1  Published: 29/Oct/2009

Title: 2-Aryl-and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof

Applicant/Assignee: WYETH

Application No.: 12/412538   Filing Date: 27/Mar/2009

Abstract:

The present invention discloses fused heterobicyclic 2-aryl- and 2-heteroarylthiazolyl compounds and their pharmaceutically acceptable salts and esters thereof, which are useful for inhibiting the growth of cancerous cells, inhibiting human breast carcinoma tumor growth in particular and to treat diseases or disorders associated with securin.

Priority: US20080039873P Applic. Date: 2008-03-27

Inventor: ZHANG NAN [US]; AYRAL-KALOUSTIAN SEMIRAMIS [US]; NGUYEN THAI HIEP [US]; NIU CHUANSHENG [US]; ROSFJORD EDWARD CHRISTIAN [US]; SUAYAN RONALD [US]


Application No.: US20090270485A1  Published: 29/Oct/2009

Title: Cell specific replication-competent viral vectors comprising a self processing peptide cleavage site

Applicant/Assignee: CELL GENESYS, INC

Application No.: 12/220686   Filing Date: 24/Jul/2008

Abstract:

Cell specific replication-competent viral vectors comprising a self processing peptide cleavage sequence are provided. The targeted replication-competent viral vectors include two or more co-transcribed genes under transcriptional control of the same heterologous transcriptional regulatory element (TRE), wherein at least a second gene is under translational control of a self processing cleavage sequence or 2A sequence. Exemplary vector constructs may further include an additional proteolytic cleavage site which provides a means to remove the self processing peptide sequence from the viral vector.

Priority: US2004-857498 Applic. Date: 2004-06-01; US20030475005P Applic. Date: 2003-06-03

Inventor: KO DEREK [US]; LI YUANHAO [US]; HARDING THOMAS [US]; FANG JIANMIN [US]; RAMESH NAGARAJAN [US]; YU DE-CHAO [US]


Application No.: US20090270528A1  Published: 29/Oct/2009

Title: RESIN SYSTEMS FOR DENTAL RESTORATIVE MATERIALS

Applicant/Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODYCORPORATE

Application No.: 12/415783   Filing Date: 31/Mar/2009

Abstract:

The disclosure provides a new photopolymerizable resin system for dental restorative materials. The resin system utilizes a thiol-ene component as the reactive diluent in dimethacrylate systems. The ternary resin system comprises a thiol monomer, an ene monomer and a dimethacrylate monomer. Use of an off-stoichiometric ratio of thiol:ene functional groups in favor of excess thiols results in enhanced overall functional group conversion, improved polymer mechanical properties, and reduced shrinkage stress of the ternary system when compared to either traditional dimethacrylate or thiol-ene resin systems.

Priority: US2006-576635 Applic. Date: 2006-04-21; WO2004US34968 Applic. Date: 2004-10-22; US20030513900P Applic. Date: 2003-10-22

Inventor: BOWMAN CHRISTOPHER N [US]; CRAMER NEIL B [US]


Application No.: US20090272656A1  Published: 05/Nov/2009

Title: Gas Sensor

Applicant/Assignee:

Application No.: 12/446046   Filing Date: 17/Oct/2007

Abstract:

A method for the determination of the carbon dioxide content of an exhaled gas stream is provided, the method comprising measuring the water vapour content of the exhaled gas stream, and determining the concentration of carbon dioxide in the exhaled gas stream from the measured water vapour content. A particular method comprises causing the gas stream to impinge on a sensing element comprising a working electrode and a counter electrode

applying an electric potential across the working electrode and counter electrode

measuring the current flowing between the working electrode and counter electrode as a result of the applied potential

and determining from the measured current flow an indication of the concentration of the water vapour in the gas stream. A sensor is also described.

Priority: GB20060020711 Applic. Date: 2006-10-18; WO2007GB03957 Applic. Date: 2007-10-17

Inventor: VARNEY MARK [GB]; GARRETT MICHAEL [GB]; WILLIAMS DERYK [GB]


Application No.: US20090274397A1  Published: 05/Nov/2009

Title: Disposable pet-waste containment bag

Applicant/Assignee:

Application No.: 12/418463   Filing Date: 03/Apr/2009

Abstract:

The disposable pet-waste containment bag is a disposable apparatus that adheres around the perimeter of the birdcage to collect the waste that falls and collects a notable distance from the interior of the cage where the birds reside. The used bag is quickly detached and easily disposed by folding all sides of the used bag toward the center to contain the waste upon removal, which keeps the pet cleaner and reduces cleanup time.

Priority: US20080124767P Applic. Date: 2008-04-21

Inventor: WONG BONNIE JOANN [US]


Application No.: US20090274577A1  Published: 05/Nov/2009

Title: STERILIZATION BY TREATMENT WITH REDUCTANT AND OXIDANT

Applicant/Assignee: B-K MEDICAL APS

Application No.: 12/433960   Filing Date: 01/May/2009

Abstract:

The present invention relates to the field of sterilization of items that are sensitive to e.g. temperature, pH, positive or negative pressure, radiation or oxidation. More particularly, the invention concerns a method, the use of this method and an apparatus for sterilization or disinfection, comprising the steps of contacting one or more item or part of an item with a water-based fluid comprising at least one reductant, followed by the step of contacting with a gas having oxidative properties in a substantially water-free environment. According to the invention, items can be sterilized that are otherwise impaired by conventional sterilization procedures, such as laboratory items, medical items, dental items, military items, biological items, and food processing-related items.

Priority: US20080071527P Applic. Date: 2008-05-05

Inventor: SORENSEN JAN [DK]; DUEHOLM BELINDA UCKEVICIUS [DK]


Application No.: US20090274634A1  Published: 05/Nov/2009

Title: Novel crosslinked polymeric substrates methods of preparation and end use applications of the substrates

Applicant/Assignee: CAPTURE TECHNOLOGIES, INC

Application No.: 12/151242   Filing Date: 05/May/2008

Abstract:

A composition of matter wherein the composition comprises a siliceous substrate having silanols on the surface and a polymer selected from the group consisting essentially of a water soluble polymer, a water soluble copolymer, an alcohol soluble polymer, an alcohol soluble copolymer, and combinations of such polymers, wherein the polymer is chemically bonded to the siliceous substrate by a silane linking material having the general formula O3/2SiQY that is derived from an alkoxy-functional silane having the general formula (RO)3SiQX and processes for preparing the crosslinked polymer that is chemically bonded to the surface of the siliceous substrate.

Priority:

Inventor: COLLINS WARDE T [US]; GRAHAM DAVID E [US]; ADAMSON DOUGLAS H [US]; MININNI ROBERT M [US]


Application No.: US20090274635A1  Published: 05/Nov/2009

Title: Bactericide having selectivity to cariogenic bacterium, and a method for sterilization of cariogenic bacterium

Applicant/Assignee: TWO CELLS CO., LTD

Application No.: 11/921876   Filing Date: 25/Jul/2006

Abstract:

The bacteriolytic effect of a bacterial cell wall lytic enzyme can be increased by the addition of a surfactant to the enzyme. As a result, the time required for lysis of cariogenic bacterium with the bacterial cell wall lytic enzyme can be shortened, and the practical utility of the bacterial cell wall lytic enzyme (such as automutanolysin) as a prophylactic or therapeutic agent for dental caries can be improved.

Priority: JP20050216099 Applic. Date: 2005-07-26; JP20060198407 Applic. Date: 2006-07-20; WO2006JP314671 Applic. Date: 2006-07-25

Inventor: SUGAI MOTOYUKI [JP]; KOMATSUZAWA HITOSHI [JP]


Application No.: US20090274993A1  Published: 05/Nov/2009

Title: PROCESS FOR PRODUCTION OF A DENTAL COMPONENT AND ARRANGEMENT OF SUCH COMPONENT

Applicant/Assignee: NOBEL BIOCARE SERVICES AG

Application No.: 12/159475   Filing Date: 22/Dec/2006

Abstract:

A manufacturing method and dental component are provided in which first and second cast parts are used with a casting material, such as a gel slurry, to form the dental component. The first cast part can be positioned in a space of the second cast part and a gel slurry can be applied intermediate the first and second cast parts. The gel slurry can then be solidified to form a solidified gel slurry. The first cast part can then be removed together with the solidified gel slurry from the second cast part. The solidified gel slurry can then be machined to form an exterior shape corresponding to a desired exterior shape of the dental component. Finally, the solidified gel slurry can be sintered.

Priority: SE20050002936 Applic. Date: 2005-12-30; WO2006SE01488 Applic. Date: 2006-12-22

Inventor: BERGSTROM LENNART [SE]; LAARZ ERIK [SE]; ADOLFSSON ERIK [SE]; BOON NG SING [SE]; ANDERSSON MATTS [SE]


Application No.: US20090275099A1  Published: 05/Nov/2009

Title: Methods and compositions for treating diseases and conditions associated with mitochondrial function

Applicant/Assignee: REGENTS OF THE UNIVERSITY OF MICHIGAN

Application No.: 11/726219   Filing Date: 21/Mar/2007

Abstract:

The present invention relates to chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides compounds as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, hyperproliferation, mitochondrial F1F0 ATP hydrolase associated disorders, and the like.

Priority: US2005-110228 Applic. Date: 2005-04-20; US20040565788P Applic. Date: 2004-04-27

Inventor: GLICK GARY D [US]


Application No.: US20090275722A1  Published: 05/Nov/2009

Title: AUTOMIXABLE PUTTY IMPRESSION MATERIAL

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY 3M ESPE AG

Application No.: 12/501655   Filing Date: 13/Jul/2009

Abstract:

The present invention relates to a multicomponent automixable putty impression material, its components, mixtures of the components and a method for obtaining impressions with the multicomponent automixable putty impression material.

Priority: EP20030017488 Applic. Date: 2003-08-01; US2004-566926 Applic. Date: 2004-07-30; WO2004EP08592 Applic. Date: 2004-07-30

Inventor: ZECH JOACHIM W [DE]; BISSINGER PETER [DE]; HOFFMANN HENNING [DE]; STEIGER WOLF [DE]


Application No.: US20090276056A1  Published: 05/Nov/2009

Title: RESORBABLE CERAMICS WITH CONTROLLED STRENGTH LOSS RATES

Applicant/Assignee: WASHINGTON STATE UNIVERSITY

Application No.: 12/298012   Filing Date: 25/Apr/2007

Abstract:

Particular aspects provide bioresorbable and biocompatible compositions for bioengineering, restoring or regenerating tissue or bone, comprising a three-dimensional porous or non-porous scaffold material comprising a calcium phosphate-based ceramic having at least one dopant therein selected from metal ion or ion dopants and metal oxide dopants, wherein the composition is sufficiently biocompatible to provide for a cell or tissue scaffold, and resorbable at a controlled resorption rate for controlled stregthloss, depending on dopant composition, under body, body fluid or simulated body fluid conditions. Preferably, the at least one dopant is selected from the group consisting of Zn2+, Mg2+, Si2+, Na+, K+, Sr2+, Cu2+, Fe3+/Fe2+, Ag+, Ti4+, CO32-, F-, MgO, ZnO, NaF, KF, FeO/Fe2O3, SrO, CuO, SiO2, TiO2, Ag2O and CaCO3, present in an amount between 0 and about 10 w %, from about 0.5 to about 5 w %, or from about 1 to about 3 w %, and methods of using same.

Priority: US20060794698P Applic. Date: 2006-04-25; WO2007US67444 Applic. Date: 2007-04-25

Inventor: BOSE SUSMITA [US]; BANDYOPADHYAY AMIT [US]


Application No.: US20090277354A1  Published: 12/Nov/2009

Title: Blasting air tube with sleeve, and method

Applicant/Assignee:

Application No.: 12/151357   Filing Date: 06/May/2008

Abstract:

An inflatable air tube includes a sleeve member arranged concentrically about the upper end portion of the air tube to define a receptacle chamber for receiving a quantity of bulk explosive blasting powder, thereby to add weight to the air tube for positioning and stabilizing the same in the bulk explosive powder during the depositing of the powder into a blasting hole drilled into the ground. According to the method of the present invention, a plurality of accurate blasting patterns may be provided in the blasting powder column by timing the manual or mechanical insertion of the air tubes into the bulk blasting powder relative to the rate of supply of the powder from a source thereof.

Priority:

Inventor: ROBERT VINCENT T [US]; CAMPBELL DUNCAN E [US]


Application No.: US20090277397A1  Published: 12/Nov/2009

Title: THERAPEUTICALLY ENHANCED PET TOY

Applicant/Assignee: PETSPORT USA, INC

Application No.: 12/118174   Filing Date: 09/May/2008

Abstract:

A pet toy comprising a toy body preferably in the shape of a ball, and at least one toy enhancing strip bonded to the surface of the toy body. The toy enhancing strip is edible, preferably shelf-stable and water soluble so as to be at least partially dissolvable by the pet's saliva as the toy is mouthed or chewed by the pet. The enhancing strip can comprise a breath freshener, a dental agent and/or a medicinal agent. The toy body can also include a second enhancement strip bonded to the toy body and formulated to attract the pet.

Priority:

Inventor: HASS PETER M [US]


Application No.: US20090277461A1  Published: 12/Nov/2009

Title: ORAL APPLIANCE

Applicant/Assignee:

Application No.: 12/504942   Filing Date: 17/Jul/2009

Abstract:

An oral appliance with opposite channels for receiving the upper and lower dental arches is made from an edible material, in particular a gel. The appliance is integrally molded with protrusions that act as brush bristles to clean the teeth and stimulate the gums when manipulated in a chewing motion. The gel composition is water soluble and degrades in saliva. After chewing on the appliance for a time to clean the teeth, the product becomes masticated, broken up and ingested. The appliance can incorporate a breath freshener or an active dental composition, or can be flavored or can incorporate a food supplement or pharmaceutical, in which case the appliance is intended to be chewed up and eaten after serving its tooth cleaning function. Dentifrice reservoirs, air passageways and lateral braces for manipulation by the tongue can be provided.

Priority: US2007-701856 Applic. Date: 2007-02-01; US20060764119P Applic. Date: 2006-02-01

Inventor: GALLAGHER JR JOHN H [US]; BIELSKI ROMAN [US]


Application No.: US20090277865A1  Published: 12/Nov/2009

Title: REUSABLE BOTTLE MOUTHPIECE AND CAP

Applicant/Assignee:

Application No.: 12/463305   Filing Date: 08/May/2009

Abstract:

A device for allowing a consumer to drink liquid from a beverage container without the consumer's mouth directly contacting the mouthpiece of the beverage container. A method for allowing a consumer to drink liquid from a beverage container without the consumer's mouth directly contacting the mouthpiece of the beverage container.

Priority: US20080052567P Applic. Date: 2008-05-12

Inventor: TAYLOR CHARLES [US]


Application No.: US20090280071A1  Published: 12/Nov/2009

Title: USE OF REPEAT SEQUENCE PROTEIN POLYMERS IN PERSONAL CARE COMPOSITIONS

Applicant/Assignee:

Application No.: 11/860911   Filing Date: 25/Sep/2007

Abstract:

A personal care composition is provided and includes an effective amount of a repeat sequence protein polymer. The personal care composition may be a hair care composition, a skin care composition, a nail care composition, a cosmetic composition, or an over-the-counter pharmaceutical composition.

Priority: US2004-800179 Applic. Date: 2004-03-12

Inventor: KUMAR MANOJ [US]; CUEVAS WILLIAM A [US]


Application No.: US20090280160A1  Published: 12/Nov/2009

Title: PHENYLEPHRINE PHARMACEUTICAL FORMULATIONS AND COMPOSITIONS FOR TRANSMUCOSAL ABSORPTION

Applicant/Assignee: SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC

Application No.: 12/328429   Filing Date: 04/Dec/2008

Abstract:

Pharmaceutical compositions comprising phenylephrine or a pharmaceutically acceptable salt thereof and methods for administering the pharmaceutical compositions wherein the composition is formulated for systemic absorption of phenylephrine that avoids first pass metabolism. The compositions of the invention are formulated to be applied to oral mucosa of an animal to allow for enhanced systemic delivery of therapeutically active form of phenylephrine.

Priority: US20070012223P Applic. Date: 2007-12-07

Inventor: MONTEITH DAVID [US]; O'MULLANE JOHN [US]; REO JOSEPH P [US]; NELSON DENNIS [US]; WAN JIANSHENG [US]; CHEN XIAOMING [US]; KABIR MOHAMMED A [US]


Application No.: US20090280450A1  Published: 12/Nov/2009

Title: PRE-FORMED HARD-SHELL ATTACHMENT DEVICES FOR DENTAL APPLIANCES

Applicant/Assignee:

Application No.: 12/118550   Filing Date: 09/May/2008

Abstract:

A dental appliance attachment device includes a rigid, substantially non-deformable shell having a hollow interior and an exterior surface defining an external configuration of the attachment device. A curable, adhesive filler is provided in the interior of the shell. The resin is adhesively bondable to the tooth surface upon being cured so as to semi-permanently bond both the shell and the filler to the surface of the tooth. The shell, with the uncured filler material, is placed on the tooth surface at a desired site with a placement device, which may be either a placement template or an elongate placement implement. The filled shell is detachably fixed to the placement device, so that when the filled shell is placed on the tooth surface, the placement device may be removed before the filler is cured to bond the attachment device to the tooth surface.

Priority:

Inventor: KUO ERIC [US]


Application No.: US20090281044A1  Published: 12/Nov/2009

Title: ELASTIN DIGEST COMPOSITIONS AND METHODS UTILIZING SAME

Applicant/Assignee:

Application No.: 12/483494   Filing Date: 12/Jun/2009

Abstract:

The present invention provides compositions for the therapeutic and/or cosmetic treatment of Elastin comprising tissues. Therapeutic and cosmetic compositions comprising an elastin digest stimulate the endogenous production of Elastin and appear to enhance the elasticity of the skin and provide an external supply of peptide precursors of Elastin that penetrate into the tissue to which it is applied. The present invention describes compositions containing an elastin digest derived from proteolytic digestion of insoluble elastin derived from mammalian ligaments with a protein digesting composition, such as proteinase K. The elastin digest is a mixture of elastin peptides wherein the elastin peptide mixture comprises peptides of the sequence GXXPG, wherein X represents one of the natural amino acids. The elastin digest of the present invention may also comprise epitopes of cytokines, growth factors and di-peptides. Methods of using these elastin digest comprising compositions for treating tissues in need of increased elasticity and or Elastin are described.

Priority: US2004-778253 Applic. Date: 2004-02-13; US20030447461P Applic. Date: 2003-02-14

Inventor: MITTS THOMAS [US]; JIMENEZ FELIPE [US]


Application No.: US20090281132A1  Published: 12/Nov/2009

Title: Pharmaceutical formulation for use in hiv therapy

Applicant/Assignee:

Application No.: 12/310693   Filing Date: 31/Aug/2007

Abstract:

The invention discloses a formulation prepared by granulating at least one anti-retro viral drug and at least one pharmaceutically acceptable additive, using an organic solvent

milling the product

finally processing the milled product to form tablets or capsules.

Priority: IN2006CH01597 Applic. Date: 2006-09-04; WO2007IN00382 Applic. Date: 2007-08-31

Inventor: VELAVENI KIRAN KUMAR NARSAIAH [IN]; VERMA SANJAY DESHRAJ [IN]; DIXIT AKHILESH ASHOK [IN]; DESHMUKH ABHIJIT MUKUND [IN]; SETHI SANJEEV MEHARCHAND [IN]; MITRA SOURAV DILIPKUMAR [IN]


Application No.: US20090281835A1  Published: 12/Nov/2009

Title: Medical prescription scheduler for reminding and compliance

Applicant/Assignee:

Application No.: 12/387270   Filing Date: 30/Apr/2009

Abstract:

A medical prescription scheduler for reminding and compliance is basically envisioned and devised to simplify the programming of a reminder device, and comprises of a single device or a pair of complimentary devices. A scheduler device is meant for achieving a speedy and facilitated scheduling of a medical prescription, formatting the scheduled prescription based on format specifications compliant with the prescription reminder application program of a recipient reminder device, and transmitting the formatted scheduled medical prescription to the reminder device. When unpacked in the receiving reminder device, said format is intended for realizing the programming of the reminder device. And the programmed reminder device is capable of audio-visually reminding each dose of each medication of said prescription till compliance. Preferably, the scheduler and reminder devices are modified commonly used electronic devices, wherein either the existing hardware and/or software is suitably adapted or the requisite hardware and/or software is incorporated so as to accomplish the scheduling and reminding function. While inputting a prescription, the computing means of a scheduler device assists a prescriber by performing relational analysis and by displaying cautionary or advisory information. In addition to facilitating a doctor in scheduling a medical prescription, a means for promoting pharmaceutical products and generating revenues is included.

Priority: IN2008MU00981 Applic. Date: 2008-05-07; IN2008MU02423 Applic. Date: 2008-11-17; US20080133750P Applic. Date: 2008-07-03

Inventor: PATWARDHAN RAVINDRA [IN]; PANDIT RAJEEV [US]


Application No.: US20090282779A1  Published: 19/Nov/2009

Title: METHOD AND APPARATUS CONFIGURED TO APPLY LABELS, SUCH AS BANDEROLES, LABEL STRIPS, OR TAX STRIPS, ON THE TOPS OF BEVERAGE BOTTLES

Applicant/Assignee: KHS MASCHINEN-UND ANLAGENBAU AG

Application No.: 12/454629   Filing Date: 20/May/2009

Abstract:

A method and apparatus configured to apply labels, such as banderoles, label strips, or tax strips, on the tops of beverage bottles. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. PRG 1.72(b). As stated in 37 C.F.R. PRG 1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading "Abstract of the Disclosure." The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner.

Priority: DE200510036398 Applic. Date: 2005-08-03; US2006-461894 Applic. Date: 2006-08-02

Inventor: FRITSCHE CLAAS [DE]; DECKERT LUTZ [DE]


Application No.: US20090283494A1  Published: 19/Nov/2009

Title: EASY CLEAN REFILLABLE BOTTLE AND DISPENSING CAP

Applicant/Assignee: TABLECRAFT PRODUCTS COMPANY

Application No.: 12/120283   Filing Date: 14/May/2008

Abstract:

A plastic refillable bottle and a plastic screw-on closure for the bottle, the bottle having a one-piece molded hollow body and integral neck, the walls of the body and neck being of generally uniform thickness, the neck having an opening through which material in the bottle passes when being dispensed and being formed with a helical thread, the closure being configured to extend across the bottle mouth and having a skirt for overlying the bottle neck, the closure skirt having a thread complementary to the thread on the neck and enabling the closure to be tightened onto the neck and effect a seal adequate to avoid excessive leakage of the contents out of the bottle through an interface between the skirt and neck, interior surfaces of the bottle and closure including the areas of the bottle and closure forming the respective threads being devoid of concave surface areas with a radius smaller than about 1/8'' at corners forming an angle of less than 135 DEG .

Priority:

Inventor: MAXWELL CHARLES P [US]


Application No.: US20090285766A1  Published: 19/Nov/2009

Title: Photosensitising Composition and Uses Thereof

Applicant/Assignee: NATIONAL UNIVERSITY OF SINGAPORE

Application No.: 11/922044   Filing Date: 13/Jun/2006

Abstract:

The present invention provides a photosensitising composition comprising a mixture of: at least one surfactant

at least one alcohol

and/or water, with the proviso that when the at least one surfactant is an alcohol, it is different from the at least one alcohol. In particular, the composition may comprise a mixture of glycerol, ethanol and water. Alternatively, the composition may comprise a mixture of polyethylene glycol, ethanol and water. The photosensitising composition may further comprise at least one photosensitising compound. The present invention also provides a method of treating and/or preventing conditions caused by microorganisms in a subject.

Priority: US20050689997P Applic. Date: 2005-06-13; WO2006SG00154 Applic. Date: 2006-06-13

Inventor: KISHEN ANIL [SG]; GEORGE SAJI [SG]; NEO CHIEW LIAN JENNIFER [SG]; SONG KEANG-PENG [MY]


Application No.: US20090285888A1  Published: 19/Nov/2009

Title: DERIVATIVES OF DIHYDROXYPHENYLALANINE

Applicant/Assignee:

Application No.: 11/914207   Filing Date: 14/May/2006

Abstract:

The invention relates to derivatives of dihydroxyphenylalanine, to their synthesis and to pharmaceutical compositions containing said derivatives of dihydroxyphenylalanine. Furthermore, the invention relates to the use of said derivatives of dihydroxyphenylalanine and said pharmaceutical compositions for the treatment and prophylaxis of movement disorders, neurodegenerative diseases, Alzheimer's disease, Parkinson's disease, hemiparkinson-hemiatrophy, parkinsonian syndrome, Lewy body disease, frontotemporal dementia, Lytico-Bodig disease (parkinsonism/dementia/amyotrophic lateral sclerosis), striatonigral degeneration, Shy-Drager syndrome, sporadic olivopontocerebellar degeneration, progressive atrophy of the globus pallidus, progressive supranuclear palsy, Hallervorden-Spatz disease, Huntington's disease, X-linked dystonia-parkinsonism (Lubag), mitochondrial cytopathy with striatal necrosis, neuroacanthocytosis, restless legs syndrome, Wilson's disease.

Priority: WO2006DE00830 Applic. Date: 2006-05-14; DE200510022276 Applic. Date: 2005-05-13

Inventor: SUSILO GISELA [DE]


Application No.: US20090286205A1  Published: 19/Nov/2009

Title: Prefabricated Dental Crowns

Applicant/Assignee:

Application No.: 12/510245   Filing Date: 27/Jul/2009

Abstract:

Advanced material is preferably used for the manufacturing of dental crowns which may be used to restore decayed or to protect other compromised tooth structure. The dental crowns are preferably preformed or prefabricated with a strengthener by way of either (1) a metal crown base (for example, a stainless steel crown base) having an advanced material (which may include fillers) applied coating or layer

or (2) an advanced material with a strengthener in the form of a strip and/or fillers. In either of the foregoing, or independently, the advanced material may be formed or applied by flame spray, liquid dispersion, powder coating, compression molding, vacuum forming, injection molding, pressure forming, or thermoforming.

Priority: US2007-677574 Applic. Date: 2007-02-21; US20060775168P Applic. Date: 2006-02-21

Inventor: JOHNSON JASON K [US]; KRUEGER D JOHNSON [US]


Application No.: US20090286298A1  Published: 19/Nov/2009

Title: MICROFLUIDIC DEVICE, SYSTEM, AND METHOD FOR CONTROLLED ENCAPSULATION OF PARTICLES OR PARTICLE CLUSTERS

Applicant/Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE

Application No.: 12/465112   Filing Date: 13/May/2009

Abstract:

A microfluidic device for controlled encapsulation of particles of sub-millimetric dimensions, or clusters of such particles, the device comprising: a first duct for delivering a first liquid phase containing particles for encapsulating in suspension

a second duct for conveying a flow of a second liquid phase that is immiscible with said first liquid phase

the first duct opening out into the second duct and forming a fluidic junction therewith

at least one microfluidic duct for discharging the first liquid phase flowing in said first duct and provided with a mouth located upstream from said junction and liable to be obstructed, at least in part, by a particle in suspension, thereby causing pressure to rise in the first duct. The invention also provides a microfluidic system including such a device, and a method of encapsulation based on using such a device.

Priority: FR20080002578 Applic. Date: 2008-05-13

Inventor: RIVERA FLORENCE [FR]; BERTHIER JEAN [FR]; VOT SOPHIE LE [FR]


Application No.: US20090286666A1  Published: 19/Nov/2009

Title: LANTHANUM OXIDE-DOPED GLASS-CERAMICS

Applicant/Assignee: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION

Application No.: 12/465093   Filing Date: 13/May/2009

Abstract:

Glass-ceramic compositions exhibiting high reliability and tensile strength are described. The compositions can include crystal phases including roedderite and/or potassium fluorrichterite. The glass-ceramic compositions are bioactive, and can be used as components of a wide variety of biomedical devices such as dental restorations.

Priority: US20080052859P Applic. Date: 2008-05-13

Inventor: DENRY ISABELLE L [US]; HOLLOWAY JULIE A [US]


Application No.: US20090286754A1  Published: 19/Nov/2009

Title: Method of Treating Cancer and Other Conditions or Disease States Using L-Cytosine Nucleoside Analogs

Applicant/Assignee: YALE UNIVERSITY

Application No.: 11/992044   Filing Date: 22/Nov/2006

Abstract:

The present invention relates to the use of the compound according to formula (I) Where S is (A) or (B)

X is H or F

R1 is H, an acyl group, a C1-C20 alkyl or ether group, a phosphate, diphosphate, triphosphate or a phosphodiester group, a (C) or (D) group

Where Nu is a radical of a biologically active compound such as an anticancer, antihyperproliferative or antiviral compound such that an amino group or hydroxyl group from said biologically active agent forms a phosphate, phosphoramidate, carbonate or urethane group with the adjacent moiety

Each R8 is independently H, or a C1-C20 alkyl or ether group, preferably H or a C1-C2 alkyl group

k is 0-12, preferably, 0-2

R2 is H, an acyl group or a C1-C20 alkyl or ether group

and pharmaceutically acceptable salts, solvates or polymorphs thereof for the treatment of tumors, cancer and hyperproliferative diseases, among other conditions or disease states.

Priority: US20050741730P Applic. Date: 2005-12-02; WO2006US45270 Applic. Date: 2006-11-22

Inventor: CHENG YUNG-CHI [US]


Application No.: US20090286767A1  Published: 19/Nov/2009

Title: SUBSTITUTED QUINOLIN-4-YLAMINE ANALOGUES

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 12/368302   Filing Date: 09/Feb/2009

Abstract:

Substituted quinolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US2004-891832 Applic. Date: 2004-07-14; US20030486948P Applic. Date: 2003-07-14

Inventor: BAKTHAVATCHALAM RAJAGOPAL [US]; CALDWELL TIMOTHY M [US]; CHENARD BERTRAND L [US]; DE LOMBAERT STEPHANE [US]; HODGETTS KEVIN J [US]


Application No.: US20090286811A1  Published: 19/Nov/2009

Title: FUSED PYRIMIDINEONE COMPOUNDS AS TRPV3 MODULATORS

Applicant/Assignee: GLENMARK PHARMACEUTICALS S.A

Application No.: 12/421145   Filing Date: 09/Apr/2009

Abstract:

The present invention provides transient receptor potential vanilloid (TRPV) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPV3. Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPV3.

Priority: IN2008MU00902 Applic. Date: 2008-04-23; IN2008MU01201 Applic. Date: 2008-06-05; IN2008MU01687 Applic. Date: 2008-08-08; IN2008MU02174 Applic. Date: 2008-10-10; US20080057971P Applic. Date: 2008-06-02; US20080113344P Applic. Date: 2008-11-11; US20080074112P Applic. Date: 2008-06-19; US20080092324P Applic. Date: 2008-08-27

Inventor: LINGHAM PRASADA RAO V S [IN]; CHAUDHARI SACHIN SUNDARLAL [IN]; THOMAS ABRAHAM [IN]; KHAIRATKAR-JOSHI NEELIMA [IN]; KATTIGE VIDYA GANAPATI [IN]


Application No.: US20090286867A1  Published: 19/Nov/2009

Title: COMPOSITIONS AND METHODS OF ADMINISTERING DOXEPIN TO MUCOSAL TISSUE

Applicant/Assignee: EOT RESEARCH INC

Application No.: 12/396832   Filing Date: 03/Mar/2009

Abstract:

Compositions and methods for pain relief involve delivery of doxepin to mucosal tissue. Vehicles for administering doxepin may be formulated for sustained release and/or site-specific application to maximize beneficial pain relief locally while minimizing significant adverse side effects.

Priority: US2007-684515 Applic. Date: 2007-03-09; US2004-868505 Applic. Date: 2004-06-14; US20030478438P Applic. Date: 2003-06-12

Inventor: OIEN HAL J [US]; TRUELOVE EDMOND [US]; EPSTEIN JOEL [US]


Application No.: US20090286886A1  Published: 19/Nov/2009

Title: RESORBABLE POLYMER COMPOSITIONS FOR USE IN MEDICINE, DENTISTRY, AND SURGERY

Applicant/Assignee:

Application No.: 12/302288   Filing Date: 22/May/2007

Abstract:

We describe the medical, dental, and surgical uses of modified poly(alkylene) materials which are fully resorbable after implantation into the body, and compositions formulated with such modified poly(alkylene) materials.

Priority: US20060802115P Applic. Date: 2006-05-22; WO2007US12122 Applic. Date: 2007-05-22

Inventor: FISHER TIMOTHY C [US]; ARMSTRONG JONATHAN K [US]; CAMBRIDGE JOHN [US]; WELLISZ TADEUSZ Z [US]


Application No.: US20090288309A1  Published: 26/Nov/2009

Title: Dryer, In Particular for Powdered or Granular Material

Applicant/Assignee:

Application No.: 12/469984   Filing Date: 21/May/2009

Abstract:

The dryer comprises a casing having a longitudinal axis, a mixing shaft, a circular plate that seals an opening made in one of the end walls of the casing, and a frame supporting the casing and the shaft. In the edge portion of the opening closest to the chamber a first circumferential groove is made which is formed by a first radial cavity and by a second radial cavity deeper than the first, joined by an axial portion. An annular sealing element made of a non-stick material, having a cross-section comprising at least one axial strip and one radial strip, is inserted into the first groove in such a way that the radial strip is inserted into the second cavity and the axial strip occupies the axial portion and the mouth of the first radial cavity. A first sealing ring comprising at least one core of elastomeric material is inserted into the first cavity so as to radially compress the axial strip against the plate and a second sealing ring comprising at least one core of elastomeric material is inserted into the second cavity so as axially to compress the radial strip.

Priority: EP20080425377 Applic. Date: 2008-05-26

Inventor: DEBOLINI PAOLO [IT]


Application No.: US20090288475A1  Published: 26/Nov/2009

Title: Skimmer for Concentrating an Aerosol

Applicant/Assignee: ENERTECHNIX, INC

Application No.: 12/125458   Filing Date: 22/May/2008

Abstract:

A skimmer device for concentrating an aerosol from a flowing gas stream, having an inlet with inlet aperture and inlet raceway, an outlet with virtual impact void and collector channel, and bulk flow divertors symmetrically disposed on either side of the long axis of flow, further characterized in that the downstream walls of the bulk flow divertors are concavedly curved and reverse the direction of bulk flow. In section, the four channels or passages of the "skimmer" thus form a "crossed tee" with concavedly contoured lateral arms curving back around. The lateral flow channels are for diverting the bulk flow into exhaust chimney spaces, and the chimney spaces are positioned proximate to the inlet element and anterior to the collection channel. In operation, the bulk flow streamlines are thereby folded more than 90 degrees away from the long axis of flow on the laterally disposed concave walls of the bulk flow channels. While counterintuitive, this was found using computational fluid dynamics (CFD) and experimentation to dramatically reduce wall separation and related instabilities and to improve particle recoveries. Large two-dimensional arrays of closely stacked inlet and skimmer elements are thus achieved by fitting the chimneys into spaces between parallel inlet elements. The interlinked problems of flow instability, manufacturability of arrays, and scale-up of chimney cross-sectional area to equalize pressure differentials in the bulk flow diverter exhaust ducts, particularly in two-dimensional arrays at high throughput, are uniquely solved with this geometry.

Priority:

Inventor: ARIESSOHN PETER C [US]; NOVOSSELOV IGOR V [US]


Application No.: US20090288660A1  Published: 26/Nov/2009

Title: NEGATIVE-PRESSURE ORAL APPARATUS AND METHOD FOR MAINTAINING NEGATIVE ORAL PRESSURE AND COLLECTING LIQUID

Applicant/Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Application No.: 12/207841   Filing Date: 10/Sep/2008

Abstract:

The present invention discloses a negative-pressure oral apparatus capable of relieving discomfort of soft tissues in the oral cavity and improving fixation of the oral apparatus to prevent the oral apparatus from falling off due to mouth opening. The oral apparatus is compact and elastic so that it fits various shapes and sizes of the oral cavity and is easy to be put on and taken off to provide convenience and safety to the user. In another embodiment, a method for maintaining a negative oral pressure and collecting liquid by coupling the oral apparatus to a liquid collecting apparatus capable of effectively providing the oral cavity with a negative pressure to expel liquid in the oral apparatus and deliver the liquid to an absorbing element in the liquid collecting apparatus so as to prevent liquid leakage or contamination.

Priority: TW20080118459 Applic. Date: 2008-05-20; TW20080121064 Applic. Date: 2008-06-06

Inventor: CHEN CHUNG-CHU [TW]; SHEN TE-YANG [TW]


Application No.: US20090289213A1  Published: 26/Nov/2009

Title: METHOD OF PROCESSING A BIOLOGICAL AND/OR CHEMICAL SAMPLE

Applicant/Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Application No.: 12/279308   Filing Date: 08/Dec/2008

Abstract:

The invention provides a method of processing a biological and/or chemical sample. The method includes providing a fluid droplet, which includes an inner phase and an outer phase. The outer phase is immiscible with the inner phase, and the outer phase is surrounding the inner phase. The inner phase includes the biological and/or chemical sample. The fluid droplet furthermore comprises magnetically attractable matter. The method also includes providing at least one surface, which is of such a texture and such a wettability for the fluid of the inner phase of the fluid droplet, that the fluid droplet remains intact upon being contacted therewith. The method further includes disposing the fluid droplet onto the at least one surface. The method also includes performing a process on the biological and/or chemical sample in the fluid droplet.

Priority: WO2006SG00029 Applic. Date: 2006-02-13

Inventor: PIPPER JUERGEN [SG]; HSIEH TSENG-MING [SG]; NEUZIL PAVEL [SG]


Application No.: US20090291196A1  Published: 26/Nov/2009

Title: Abluminal Stent Coating Apparatus And Method Using A Brush Assembly

Applicant/Assignee: ADVANCED CARDIOVASCULAR SYSTEMS, INC

Application No.: 12/510121   Filing Date: 27/Jul/2009

Abstract:

The apparatus and method use an optical feedback system to align a brush assembly with a stent strut. Once alignment is achieved, a coating is dispensed onto the stent strut via the brush assembly and the brush assembly is moved along the stent strut to coat the stent strut.

Priority: US2004-999829 Applic. Date: 2004-11-29

Inventor: MORRIS GRAYSON [US]; ATLADOTTIR SVAVA MARIA [US]; PIENKNAGURA CARLA [US]


Application No.: US20090291415A1  Published: 26/Nov/2009

Title: Device and Method for Gingival Attachment Associated with Endosseous Implants

Applicant/Assignee: MEDINTAL LTD

Application No.: 12/306405   Filing Date: 02/Jul/2007

Abstract:

A gingival attachment device associated with an endosseous implant, which comprises a cervically located component of a dental implant coated on a gingival facing surface thereof with a biocompatible and non-degradable polymeric scaffold, to which epithelial and connective tissue cells of the gingiva are attachable. The polymeric scaffold may be polyvinylpyrronidole mixed with butyl-methylmethacrylate, silk fibroin fibrous protein polymer mixed with chitosan or with derivatives of chitosan, and polyHEMA and may be coated on all gingival facing surfaces of the cervically located component.

Priority: US20060818403P Applic. Date: 2006-07-05; IL20060177959 Applic. Date: 2006-09-07; WO2007IL00820 Applic. Date: 2007-07-02

Inventor: BINDERMAN ITZHAK [IL]; YAFFE AVINOAM [IL]; BAHAR HILA [IL]


Application No.: US20090291890A1  Published: 26/Nov/2009

Title: Factor VII polypeptides that are modified and uses thereof

Applicant/Assignee:

Application No.: 12/384915   Filing Date: 10/Apr/2009

Abstract:

Modified factor VII polypeptides and uses thereof are provided. Such modified FVII polypeptides include Factor VIIa and other forms of Factor VII. Among modified FVII polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities. Hence, such modified polypeptides are therapeutics.

Priority: US20080124021P Applic. Date: 2008-04-11

Inventor: MADISON EDWIN L [US]; THANOS CHRISTOPHER [US]


Application No.: US20090291942A1  Published: 26/Nov/2009

Title: IMIDAZO PYRIDINE DERIVATIVES

Applicant/Assignee:

Application No.: 12/468706   Filing Date: 19/May/2009

Abstract:

The invention relates to novel imidazopyridine derivatives and to their use in the treatment of diseases and disorders which may e.g. involve angiogenesis and/or pain, including autoimmune and inflammatory diseases.

Priority: EP20080156933 Applic. Date: 2008-05-26

Inventor: TARACIDO IVAN CORNELLA [US]; HARRINGTON EDMUND MARTIN [US]; HERSPERGER RENE [CH]; LATTMANN RENE [CH]; MILTZ WOLFGANG [CH]; WEIGAND KLAUS [CH]


Application No.: US20090291948A1  Published: 26/Nov/2009

Title: SULFONAMIDE PERI-SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE

Applicant/Assignee: DECODE GENETICS EHF

Application No.: 12/534390   Filing Date: 03/Aug/2009

Abstract:

Acyl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula A representative example is:

Priority: US2005-169161 Applic. Date: 2005-06-27; US20040618172P Applic. Date: 2004-10-12

Inventor: SINGH JASBIR [US]; GURNEY MARK E [US]; HATEGAN GEORGETA [US]; YU PENG [US]; ZEMBOWER DAVID [US]; ZHOU NIAN [US]


Application No.: US20090291988A1  Published: 26/Nov/2009

Title: Reversible Inhibitors of Monoamine Oxidase A and B

Applicant/Assignee:

Application No.: 11/922120   Filing Date: 14/Jun/2006

Abstract:

The instant invention relates to compounds of formula I, diagrammed below, wherein R3, E, D and Y are defined in the application, which are useful as reversible inhibitors of monoamine oxidase-B and/or monoamine oxidase-A, and therefore useful to treat or prevent neurological diseases or conditions in mammals, preferably humans.

Priority: US20050690411P Applic. Date: 2005-06-14; WO2006CA00981 Applic. Date: 2006-06-14

Inventor: OBALLA RENATA [CA]


Application No.: US20090291989A1  Published: 26/Nov/2009

Title: ISOTHIOCYANATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF

Applicant/Assignee: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY

Application No.: 12/307724   Filing Date: 06/Jul/2007

Abstract:

Provided herein are compositions of matter and pharmaceutical compositions thereof, for use in inhibiting the growth of various microbial pathogens, including bacteria, fungi, protozoa, and viral pathogens. Also provided herein are methods of treating microbial diseases/infections and cancer with the compositions. The compositions are additionally useful in wood preservation and food preservation by inhibition of microbial growth.

Priority: US20060819229P Applic. Date: 2006-07-06; WO2007US72998 Applic. Date: 2007-07-06

Inventor: MUSTAEV ARKADY [US]; KUREPINA NATALIA [US]


Application No.: US20090292366A1  Published: 26/Nov/2009

Title: Material based on a partially stabilized zirconia matrix with cerium oxide and yttrium oxide as stabilizing oxides of zirconia, a process for preparation and use of the material

Applicant/Assignee:

Application No.: 12/311590   Filing Date: 05/Oct/2007

Abstract:

A sintered ceramic material comprising: a) from 98-50% by volume of zirconia as a matrix, i) stabilized with a stabilizing composition having ii) of from about 2 to about 3 mole percent of yttria and of from about 10 to about 15 mole percent of ceria

wherein the term mole percent is related to the zirconia matrix and iii) the stabilizing composition is present in the range of from about 1:99 to about 99:1

and b) from about 2 to about 50% by volume of alumina of which from about 5 to about 90% by volume is in the form of hexagonal platelets of general formula REAl 11018, where RE stands for rare earth metal.

Priority: EP20060121793 Applic. Date: 2006-10-05; US20060849467P Applic. Date: 2006-10-05; WO2007EP60619 Applic. Date: 2007-10-05

Inventor: BURGER WOLFGANG [DE]; LEONHARDT WOLFGANG [DE]; THIEL NORBERT [DE]; STEPHAN MARC [DE]


Application No.: US20090293211A1  Published: 03/Dec/2009

Title: Odor Detecting Toothbrush

Applicant/Assignee:

Application No.: 12/129242   Filing Date: 29/May/2008

Abstract:

The present invention is directed to a dental cleaning device having, in combination, a toothbrush and a gas detecting system. The tooth brush has a brush portion and a handle portion. The brush portion of the toothbrush has dental cleaning devices allowing the user to clean teeth. The odor detection system is integrated into the toothbrush and generally comprises a gas sensor indicator for indicating presence of predetermined gas. The system allows the user to brush their teeth and either simultaneously or at differing times, detect any odors associated with bad breath. The device further allows the user a mechanism to know when bad breath causing odors are eliminated.

Priority:

Inventor: SPUNGIN MARC [US]


Application No.: US20090293225A1  Published: 03/Dec/2009

Title: VACUUM GROOMING TOOL

Applicant/Assignee: HAIR PATROL LLC

Application No.: 12/190865   Filing Date: 13/Aug/2008

Abstract:

A vacuum grooming tool is disclosed that includes a vacuum nozzle attachable to a vacuum source and has a hollow body with a mouth opening. A grooming device selected from a variety of standard animal grooming hand tools, such as a shedding blade, rake or de-matting tool, may span the mouth opening. The grooming device is positioned such that the airflow created by the vacuum source flows over at least one side of the grooming device. A vacuum cleaning tool for removing any animal hair from a grooming tool is also disclosed. A vacuum plenum of the cleaning tool is attachable to a vacuum source and has an opening for cleaning the grooming tool in one pass. The cleaning tool can be mounted on a stationary support may also include a pivot-action mechanism that connects the vacuum grooming tool or the cleaning tool to the vacuum source.

Priority: US2006-338221 Applic. Date: 2006-01-23; US2002-147802 Applic. Date: 2002-05-17; US20010291762P Applic. Date: 2001-05-17

Inventor: FREIDELL JAMES E [US]


Application No.: US20090293730A1  Published: 03/Dec/2009

Title: Two-stage air filter and mask incorporating the same

Applicant/Assignee:

Application No.: 12/461270   Filing Date: 05/Aug/2009

Abstract:

The two-stage air filter is formed of a nonwoven glass fiber first or inlet filter element and a second or outlet filter element formed of nonwoven fiber. The outlet filter element is preferably formed of either polyester material, or a blend of polyester and cotton fiber material. The first or inlet filter element is coarser than the second or outlet filter element, with the first element serving to capture larger particles while allowing smaller particles to pass therethrough to be captured by the finer second filter element. The two filter elements have a continuous and unbroken, homogeneous interface therebetween, with the attachment of the two filter elements with one another being solely at their mutual peripheries by a peripheral frame. Additional air freshening and cleaning, deodorizing, odor neutralizing, scent applying, fungicidal, bactericidal, and/or germicidal chemicals or materials may be applied to either or both filter elements.

Priority: US2007-785871 Applic. Date: 2007-04-20; US20060794849P Applic. Date: 2006-04-26

Inventor: VOLO GIOVANNI D [US]; CARABETTA SALVATORE R [US]


Application No.: US20090294315A1  Published: 03/Dec/2009

Title: Disposal and Packaging Device

Applicant/Assignee:

Application No.: 12/159920   Filing Date: 22/Dec/2006

Abstract:

A disposal device for the receipt of an item is disclosed. The disposal device comprises a container substantially impervious to liquid having a mouth formed therein through which a soiled item may be received by the container. In use, the mouth is arranged to be capable of manipulation by a single hand of a user between a mouth open position and a mouth closed position. The disposal device may also be configured to act as primary packaging for the item before use (and soiling) thereof or for storage of the item.

Priority: GB20060000024 Applic. Date: 2006-01-03; GB20060011398 Applic. Date: 2006-06-09; GB20060019909 Applic. Date: 2006-10-07; WO2006EP70180 Applic. Date: 2006-12-22

Inventor: SILCOTT MARTHA SELENE [GB]


Application No.: US20090294400A1  Published: 03/Dec/2009

Title: Synthetic Resin Bottle

Applicant/Assignee: YOSHINO KOGYOSHO CO., LTD

Application No.: 12/308578   Filing Date: 05/Jun/2007

Abstract:

There is provided a synthetic resin bottle having high commercial value, which prevents plastic deformation accompanied with buckling. The invention provides a PET bottle comprising a body portion connected to a mouth portion via a shoulder portion, and a constricted portion provided on the body portion and looping along the circumferential direction. The body portion comprises a front wall and a back wall which face to each other, a left sidewall and a right sidewall which face to each other, and connecting portion which respectively join the walls. The cross section of the body portion along the circumferential direction a generally polygonal outer profile. The constricted portion comprises left lateral grooves extending from the left sidewall at least to the connecting portion along the circumferential direction, right lateral grooves extending from the right sidewall at least to the connecting portion along the circumferential direction and intermittent portions formed by spacing apart adjacent terminal ends of the lateral grooves.

Priority: JP20060182754 Applic. Date: 2006-06-30; WO2007JP61380 Applic. Date: 2007-06-05

Inventor: SASAKI MASAAKI [JP]; IIZUKA TAKAO [JP]


Application No.: US20090297071A1  Published: 03/Dec/2009

Title: FLEXIBLE BAG WITH VENT FOR PRESSURE RELEASE

Applicant/Assignee: ILLINOIS TOOL WORKS INC

Application No.: 12/472572   Filing Date: 27/May/2009

Abstract:

A flexible bag having a reclosable zipper construction in which material is provided on the inside face of one or both zipper flanges that results in a weak seal area or an unsealed area when the side seals are made. The weak seal area or unsealed area is located on the product side of the zipper closure profiles. Elevated pressure inside the bag will cause the weak seal area of the side seal to fail as intended or will cause the zipper flanges in the unsealed area to separate, resulting in a venting action during cooking of the bag contents. For example, steam inside the bag can escape through the vent or vents while the zipper remains closed. Preferably the bag has a bottom gusset so that it can stand upright in a microwave oven. The bag may be opened to add contents, resealed and then heated.

Priority: US20080056691P Applic. Date: 2008-05-28

Inventor: KOENIGKRAMER RUSTY E [US]; ANZINI DAVID J [US]


Application No.: US20090297458A1  Published: 03/Dec/2009

Title: Dental materials equipped with active anti-plaque substance(s)

Applicant/Assignee: HERAEUS KULZER GMBH

Application No.: 12/429353   Filing Date: 24/Apr/2009

Abstract:

A process by means of which the colonisation by plaque on dental materials can be permanently prevented or delayed without the product properties of the dental material being negatively influenced. The process involves equipping the dental material with anti-plaque substance, namely at least one molecularly dispersely distributed octenidine salt or dequalinium salt. Also disclosed is a dental material so equipped.

Priority: DE200810021473 Applic. Date: 2008-04-29

Inventor: RUPPERT KLAUS [DE]; RENZ KARL-HEINZ [DE]; VOGT SEBASTIAN [DE]


Application No.: US20090297482A1  Published: 03/Dec/2009

Title: PROBIOTIC STRAIN AND ANTIMICROBIAL PEPTIDE DERIVED THEREFROM

Applicant/Assignee:

Application No.: 12/302067   Filing Date: 25/May/2007

Abstract:

The invention relates to a strain of Enterococcus mundtii having probiotic qualities. The strain of E. mundtii (ST4SA) produces an antimicrobial peptide which exhibits antimicrobial activity against a broad range of bacteria. The invention also provides an isolated nucleotide sequence which codes for the antimicrobial peptide (peptide ST4SA). Another aspect of the invention relates to a process for the production of a peptide of the invention which comprises cultivating Enterococcus mundtii strain ST4SA in a nutrient medium under micro-aerophilic conditions at a temperature of between 100C and 45 DEG C., until a recoverable quantity of said peptide is produced, and recovering said peptide. The isolated peptide of the invention may be used as an antimicrobial agent in a liquid formulation or a gel formulation as a topical treatment and may also be used as an antimicrobial agent following encapsulation in a polymer.

Priority: ZA20060004035 Applic. Date: 2006-05-28; WO2007IB51982 Applic. Date: 2007-05-25; BE20050000272 Applic. Date: 2005-05-31

Inventor: DICKS LEON MILNER THEODORE [ZA]; TODOROV SVETOSLAV DIMITROV [ZA]; KNOETZE HENDRIETTE [ZA]; BRINK MARELIZE [ZA]


Application No.: US20090297555A1  Published: 03/Dec/2009

Title: RECOMBINANT HUMAN CYTOMEGALOVIRUS AND VACCINES COMPRISING HETEROLOGOUS ANTIGENS

Applicant/Assignee: MEDIMMUNE, LLC

Application No.: 12/495241   Filing Date: 30/Jun/2009

Abstract:

The present invention relates to recombinant HCMV (human cytomegalovirus) expressing a pp65 polypeptide or fragment thereof fused to a heterologous or non-native polypeptide, in particular immunogenic and/or antigenic polypeptides. In particular, the heterologous gene products include antigenic or immunogenic polypeptides from a variety of pathogens, cellular genes, tumor antigens, and viruses. The recombinant viruses may advantageously be used in vaccine formulations including vaccines against a broad range of pathogens and antigens.

Priority: US2007-571081 Applic. Date: 2007-08-01; WO2005US22734 Applic. Date: 2005-06-24; US20040583188P Applic. Date: 2004-06-25

Inventor: KEMBLE GEORGE [US]; GREENBERG HARRY [US]; DUKE GREGORY [US]


Application No.: US20090297569A1  Published: 03/Dec/2009

Title: Oral hygiene tablets and capsules for direct oral delivery of active ingredients

Applicant/Assignee:

Application No.: 12/156609   Filing Date: 03/Jun/2008

Abstract:

An oral hygiene tablet or capsule for direct oral delivery of active ingredients to humans and animals is provided composed of a tablet or capsule having an outer shell and inner cavity containing an active ingredient. Active ingredients contained and delivered by the oral hygiene tablet include mouthwash, toothpaste, medicament, mouth soothing and numbing agents, fluoride rinse, joint preserving agents, vitamins and herbal supplements. Other ingredients, such as flavor enhancers, scents, colorings and sugars may be included in the composition of the tablet or capsule. Delivery of the supplement ingredients is effectuated by simply placing the tablet into the mouth and allowing saliva to cause the outer shell to dissolve. The dissolution process can be accelerated by biting of the tablet/capsule and breaking it into smaller particles and/or by drinking water when the tablet is inserted into the mouth.

Priority:

Inventor: HURWITZ MARNI MARKELL [US]


Application No.: US20090298004A1  Published: 03/Dec/2009

Title: TUNNELLING PROBE

Applicant/Assignee:

Application No.: 12/426940   Filing Date: 20/Apr/2009

Abstract:

An electromagnetically induced cutting mechanism provides accurate cutting operations on soft tissues. The electromagnetically induced cutter is adapted to interact with atomized fluid particles. A tissue remover comprises an aspiration cannula housing a fluid and energy guide for conducting electromagnetically induced cutting forces to the site within a patient's body for aspiration of soft tissue. An endodontic probe is used to perform disinfection procedures on target tissues within root canal passages and tubules. The endodontic probe can include an electromagnetic radiation emitting fiber optic tip having a distal end and a radiation emitting region disposed proximally of the distal end. According to one aspect, the endodontic probe can include a porous structure that encompasses a region of the fiber optic tip excluding the radiation emitting region and that is loaded with biologically-active particles, cleaning particles, biologically-active agents, or cleaning agents for delivery from the porous structure onto the target tissues. Another aspect can include provision of the endodontic probe with an adjustable channel-depth indicator, which encompasses a region of the fiber optic tip besides the radiation emitting region and which is movable in proximal and distal directions along a surface of the fiber optic tip to facilitate the provision of depth-of-insertion information to users of the endodontic probe.

Priority: US2008-234593 Applic. Date: 2008-09-19; US2003-667921 Applic. Date: 2003-09-22; US2000-714479 Applic. Date: 2000-11-15; US1998-188072 Applic. Date: 1998-11-06; US20080046394P Applic. Date: 2008-04-18; US20070995759P Applic. Date: 2007-09-28; US20070994891P Applic. Date: 2007-09-21; US20070994723P Applic. Date: 2007-09-20; US20070994571P Applic. Date: 2007-09-19; US19970064465P Applic. Date: 1997-11-06

Inventor: RIZOIU IOANA M [US]


Application No.: US20090298005A1  Published: 03/Dec/2009

Title: Single Use Periodontal Probe

Applicant/Assignee:

Application No.: 12/475783   Filing Date: 01/Jun/2009

Abstract:

The subject invention provides single use periodontal probes. In preferred embodiments as described herein the probes of the subject invention can be used with a recording apparatus for simultaneously measuring and recording the depth of the periodontal pocket (gingival sulcus) and more particularly, to a unit employing a periodontal depth probe operably connected to a recording device, capable of producing a permanent visual record of the measured pocket depth. In further embodiments, the probes of the subject invention can be used to deliver and/or collect materials for prevention, treatment and/or diagnosis of periodontal conditions.

Priority: US20080057823P Applic. Date: 2008-05-31

Inventor: GIBBS CHARLES H [US]; GIBBS CHRIS [US]


Application No.: US20090298009A1  Published: 03/Dec/2009

Title: GUIDE DEVICE ABLE TO INTERACT WITH A NUMBER OF SLEEVES DISPOSED IN A TOOTH TEMPLATE

Applicant/Assignee: NOBEL BIOCARE AB

Application No.: 12/538811   Filing Date: 10/Aug/2009

Abstract:

A guide device is provided that can interact with a number of sleeves of a tooth template. The guide device can include a handle part, a support part, and a guide part. The handle part can include first and second parts. The first part can be connectable to the second part, and the second part can include a space having a variable size. The variable size of the space can be determined by the position of the first part relative to the second part. The supporting part can be sized and configured to engage the space of the handle for allowing selective positioning of the supporting part relative to the handle part. The guide part can be connectable to the supporting part with the guide part being operative to align a tool for use in the dental treatment.

Priority: SE20040001984 Applic. Date: 2004-08-05; US2007-573193 Applic. Date: 2007-07-06; WO2005SE01074 Applic. Date: 2005-07-04

Inventor: BRAJNOVIC IZIDOR [SE]


Application No.: US20090298016A1  Published: 03/Dec/2009

Title: Integrated porcelain system for a dental prosthesis

Applicant/Assignee:

Application No.: 12/156169   Filing Date: 30/May/2008

Abstract:

An integrated dental porcelain system for making dental prostheses and restorations is provided. The system includes three universal major components: a) opaque porcelain composition

b) pressable dentin ingot

and c) veneering porcelain composition that can be used interchangeably for making restorations. Techniques for making the prostheses and restorations include porcelain fused-to-metal (PFM), press-to-metal (PTM), and either pressed and/or machined all-ceramic methods. The system uses both a hand-layering of veneering porcelain (PFM technique) and a hot-pressing process (PTM and all-ceramic technique) to fabricate the prostheses and restorations.

Priority:

Inventor: CHU CHRISTOPHER [US]; BANASIAK SLAWOMIR [US]; SHTESSEL-NEMZER VICTORIYA [US]


Application No.: US20090298759A1  Published: 03/Dec/2009

Title: C-Reactive Protein and Its Use to Treat Systemic Lupus Erythematosus and Related Conditions

Applicant/Assignee: STC.UNM

Application No.: 12/083055   Filing Date: 26/Oct/2006

Abstract:

The present invention relates to the use of C-reactive protein, its mutants, metabolites and polypeptides and related compounds thereof for the treatment of various disease states and conditions associated with systemic lupus erythematosus (SLE), including lupus of the skin (discoid), systemic lupus of the joints, lungs and kidneys, hematological conditions including hemolytic anemia and low lymphocyte counts, lymphadenopathy and CNS effects including memory loss, seizures and psychosis, among numerous others as otherwise disclosed herein, in another aspect of the invention, the reduction in the likelihood that a patient who is at risk for an outbreak of a disease state or condition with systemic lupus erythematosus will have an outbreak is an additional aspect of the present invention.

Priority: US20050730013P Applic. Date: 2005-10-26; WO2006US41583 Applic. Date: 2006-10-26

Inventor: DU CLOS TERRY W [US]; MOLD CAROLYN [US]


Application No.: US20090298825A1  Published: 03/Dec/2009

Title: Bicycloheteroaryl Compounds as P2x7 Modulators and Uses Thereof

Applicant/Assignee:

Application No.: 12/225276   Filing Date: 16/Mar/2007

Abstract:

Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: Formula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

Priority: US20060783121P Applic. Date: 2006-03-16; US20060782782P Applic. Date: 2006-03-16; US20060783304P Applic. Date: 2006-03-16; US20060782973P Applic. Date: 2006-03-16; US20060783590P Applic. Date: 2006-03-16; US20060782922P Applic. Date: 2006-03-16; US20060782776P Applic. Date: 2006-03-16; US20060782775P Applic. Date: 2006-03-16; US20060783748P Applic. Date: 2006-03-16; US20060831416P Applic. Date: 2006-07-17; US20060846993P Applic. Date: 2006-09-25; US20070918123P Applic. Date: 2007-03-15; US20060782923P Applic. Date: 2006-03-16; WO2007US06676 Applic. Date: 2007-03-16

Inventor: KELLY MICHAEL G [US]; KINCAID JOHN [US]; FANG YUNFENG [US]; CAO YEYU [US]; KAUB CARL [US]; GOWLUGARI SUMITHRA [US]; WANG ZHAN [US]


Application No.: US20090298936A1  Published: 03/Dec/2009

Title: METHOD FOR ENERGIZING HUMAN BEINGS

Applicant/Assignee: SYMRISE GMBH & CO. KG

Application No.: 12/128808   Filing Date: 29/May/2008

Abstract:

The present invention relates to a method for energizing a human being and to administering an energizing (personal care) composition to human beings wherein said composition contains one or more fragrance materials of group (a) of the present invention.

Priority:

Inventor: CLOTHIER JR JAMES G [US]; MCDERMOTT KEITH [US]; BELLON PATRICE [FR]


Application No.: US20090298987A1  Published: 03/Dec/2009

Title: Polymer resin composition

Applicant/Assignee:

Application No.: 11/662618   Filing Date: 29/Aug/2005

Abstract:

The invention provides a polymeric composition comprising: a) at least one resin selected from the group consisting of vinyl ester resins, unsaturated polyester resins, acrylates and methacrylates, b) at least one copolymer having resin-reactive groups and a glass transition temperature Tg of -20 DEG C. or less, c) nanoparticles having an average particle size dmax as measured by means of small-angle neutron scattering (SANS) of 5 to 150 nm. The compilation according to the invention allows the production of composite materials, coatings, casting compositions, adhesives, and dental materials which have enhanced mechanical properties, particularly enhanced impact strength.

Priority: EP20040021553 Applic. Date: 2004-09-10; WO2005EP09294 Applic. Date: 2005-08-29

Inventor: EGER CHRISTIAN [DE]; SPRENGER STEPHAN [DE]


Application No.: US20090299006A1  Published: 03/Dec/2009

Title: Dental Adhesive Primer Composition

Applicant/Assignee:

Application No.: 12/227641   Filing Date: 24/May/2006

Abstract:

The present invention relates to a dental adhesive primer composition for use in dental fields employed to bond dental materials, such as restoration materials, dental crown materials, prosthetic materials, esthetic materials, orthodontic materials, preventive materials, core build-up materials and root canal materials, to ceramics, metals, resins, composite resins, glass ionomer cements, and hard biotissues (enamel or dentin of natural tooth). The present invention also relates to a dental adhesive primer composition including a dental adhesive composition which can be used not only in combination with another adhesive composition but also alone.

Priority: WO2006JP310378 Applic. Date: 2006-05-24

Inventor: SHINNO KAZUYA [JP]; NAKATSUKA TOSHIYUKI [JP]; NAGAFUJI AKIHIRO [JP]


Application No.: US20090301346A1  Published: 10/Dec/2009

Title: DENTAL RESIN-BASED CEMENT COMPOSITION

Applicant/Assignee:

Application No.: 12/448049   Filing Date: 05/Jun/2009

Abstract:

The present invention provides a dental resin cement composition comprising at least two kinds of pastes, one kind of a paste comprising (a) 20 to 50 parts by weight of a polymerizable monomer composition and (b) 50 to 80 parts by weight of a filler consisting of an inorganic compound, or an organic composite comprising an inorganic compound, amounts of (a) and (b) being based on conversion of 100 parts by weight of the dental resin-based cement composition paste, and the filler (b) comprising (c) 2.0 to 10.0 parts by weight of fine silica particles based on the above conversion, and having (d) a yield viscosity of from 100 to 3,000 [Pa.s], and (e) a thixotropy index of 3.0 or more

and another kind of a paste having the same constituent features (a) to (c) and (e) except that the paste has (d) a yield viscosity of from 70 to 4,000 [Pa.s], wherein upon use, the at least two kinds of pastes are used by mixing them.

Priority: WO2006JP324354 Applic. Date: 2006-12-06

Inventor: TANAKA HISAKI [JP]; FUJII TOSHIHIDE [JP]; KOHRO YOSHIAKI [JP]; TORII KEISUKE [JP]; DEGUCHI MIKITO [JP]


Application No.: US20090301604A1  Published: 10/Dec/2009

Title: PORTABLE FLUID TREATING AND DISPENSING DEVICE, SYSTEMS, ARTICLES, AND METHODS

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 12/136220   Filing Date: 10/Jun/2008

Abstract:

Disclosed are portable fluid treating and dispensing devices, systems, articles, and methods particularly adapted for use in treating potable liquids, such as drinking water, and dispensing it into a plurality of portable potable liquid containers, such as water bottles.

Priority:

Inventor: WILLIAMS BENJAMIN P [US]; KINZER KEVIN [US]; OLSON JUDD D [US]; REUTER ROBERT J [US]; MCGREEVY SEAN C [US]


Application No.: US20090304608A1  Published: 10/Dec/2009

Title: Aqueous Hydrogen Peroxide Solution for Use as a Disinfectant or Anti-Microbial Personal Care Product

Applicant/Assignee: INNOVASOURCE, LLC

Application No.: 12/133523   Filing Date: 05/Jun/2008

Abstract:

An aqueous hydrogen peroxide solution for use in disinfectants, soaps, shower gels, and mouth rinses is provided, with improved disinfectant and anti-microbial activity. The solutions contain at least one phosphorus based acid compound, e.g. phosphoric and/or a phosphonate and a cationic or non-ionic surfactant. Importantly, the solutions do not require the presence of an anionic surfactant to achieve the objects of the invention, thus enabling successful manufacturing using multiple formulation methods. The solution may also contain fragrances, degreasers, flavors, or other additives depending on the purposes and intended functions of the solutions.

Priority:

Inventor: CUEMAN GLENN F [US]; RAMSEY BARNWELL S [US]; VEST KENNETH R [US]


Application No.: US20090304622A1  Published: 10/Dec/2009

Title: METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS

Applicant/Assignee: CHARITE-UNIVERSITATSMEDIZIN BERLIN ERNST MUHLBAUER GMBH & CO. KG

Application No.: 12/300437   Filing Date: 11/May/2007

Abstract:

The present invention refers to a method of infiltrating enamel for the prevention and/or treatment of carious lesions comprising (a) exposing an enamel area to a conditioner comprising hydrochloric acid

(b) exposing the conditioned enamel area to an infiltrant

and (c) curing the infiltrant. The present invention further refers to a kit for carrying out the method of infiltrating enamel, which comprises a conditioner comprising hydrochloric acid and an infiltrant comprising at least one low viscous dental resin. Alternatively, the kit comprises ready-to-use means for carrying out the method of infiltrating enamel, e.g. application strips with delivery pads soaked with conditioner or infiltrant. The present invention also refers to a method for identifying an infiltrant by calculation of the penetration coefficient, and to an infiltrant identified by the method having a penetration coefficient of >50 cm/s or comprising a low viscous light curing resin having a penetration coefficient of >50 cm/s.

Priority: EP20060021966 Applic. Date: 2006-10-19; US2006-432271 Applic. Date: 2006-05-11; WO2007EP04204 Applic. Date: 2007-05-11

Inventor: MEYER-LUECKEL HENDRIK [DE]; PARIS SEBASTIAN [DE]; MUELLER JAN [DE]; KIELBASSA ANDRIJ M [DE]; DETJE BERND [DE]


Application No.: US20090304713A1  Published: 10/Dec/2009

Title: BINDING AGENTS

Applicant/Assignee: AMGEN INC UCB PHARMA S.A

Application No.: 12/276889   Filing Date: 24/Nov/2008

Abstract:

Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.

Priority: US2006-411003 Applic. Date: 2006-04-25; US20050677583P Applic. Date: 2005-05-03; US20060776847P Applic. Date: 2006-02-24; US20060782244P Applic. Date: 2006-03-13; US20060792645P Applic. Date: 2006-04-17

Inventor: PASZTY CHRISTOPER [US]; ROBINSON MARTIN KIM [GB]; GRAHAM KEVIN [US]; HENRY ALISTAIR JAMES [GB]; HOFFMANN KELLY SUE [US]; LATHAM JOHN [US]; LU HSIENG SEN [US]; LAWSON ALASTAIR [GB]; POPPLEWELL ANDY [GB]; SHEN WENYAN [US]; WINKLER DAVID G [US]; WINTERS AARON GEORGE [US]


Application No.: US20090304735A1  Published: 10/Dec/2009

Title: Immunogenic Compositions

Applicant/Assignee:

Application No.: 12/227515   Filing Date: 18/May/2007

Abstract:

The present invention relates to an immunogenic composition for raising an immune response to an antigen, the composition comprising the antigen and a targeting moiety specific for lymph-resident dendritic cells. Use of the immunogenic composition in a vaccine and methods of boosting an immune response using the composition are also provided. Conversely, the invention also relates to immunogenic composition for raising an immune response to an antigen, the composition comprising the antigen and a targeting moiety specific for tissue-derived dendritic cells and a vaccine comprising said composition.

Priority: US20060801998P Applic. Date: 2006-05-19; WO2007AU00691 Applic. Date: 2007-05-18

Inventor: BELZ GABRIELLE THERESE [AU]; HEATH WILLIAM ROSS [AU]


Application No.: US20090304776A1  Published: 10/Dec/2009

Title: TRANSMUCOSAL DELIVERY OF THERAPEUTIC AGENTS AND METHODS OF USE THEREOF

Applicant/Assignee:

Application No.: 12/339126   Filing Date: 19/Dec/2008

Abstract:

Described herein is a transmucosal delivery device and their use for delivering bioactive agents across a mucosal membrane. The delivery devices contain a pharmaceutically acceptable oxidizing and agents that facilitates the delivery of the blood stream across the mucosal membrane.

Priority: US20080131241P Applic. Date: 2008-06-06

Inventor: SHANTHA TOTADA [US]; SHANTHA JESSICA [US]; SHANTHA ERICA [US]; SHANTHA LAUREN [US]


Application No.: US20090304791A1  Published: 10/Dec/2009

Title: SOLID ORAL FORMS OF EBASTINE

Applicant/Assignee: SIMBEC IBERICA, S.L

Application No.: 12/092477   Filing Date: 20/Oct/2006

Abstract:

The invention relates to compositions in the form of matrices consisting of solid ebastine dispersions in nonionic surfactants having a HLB of between 10 and 20 and a melting point of between 30 DEG C. and 70 DEG C. The invention also relates to solid oral pharmaceutical forms of ebastine containing said matrices, particularly tablets, and having good solubility and bioavailability properties and improved stability.

Priority: ES20050002686 Applic. Date: 2005-11-04; WO2006ES00581 Applic. Date: 2006-10-20

Inventor: ROMA MILLAN JORDI [ES]; MESTRE CASTELL JOSE [ES]; SUNE NEGRE JOSE MARIA [ES]


Application No.: US20090304809A1  Published: 10/Dec/2009

Title: DENTAL FILLERS, METHODS, COMPOSITIONS INCLUDING A CASEINATE

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/719472   Filing Date: 07/Nov/2005

Abstract:

The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes a caseinate. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment. Dental compositions, and methods of using dental compositions that include a caseinate and a hardenable resin or a water-dispersible, polymeric film former are also provided.

Priority: US2004-989523 Applic. Date: 2004-11-16; WO2005US40340 Applic. Date: 2005-11-07

Inventor: RUSIN RICHARD P [US]; MITRA SUMITA B [US]; CUMMINGS KEVIN M [US]; BURGIO PAUL A [US]; FALSAFI AFSHIN [US]


Application No.: US20090304854A1  Published: 10/Dec/2009

Title: FREEZE-DRIED, DAIRY OR DAIRY-SUBSTITUTE COMPOSITIONS AND METHODS OF USING SAME

Applicant/Assignee: NESTEC S.A

Application No.: 12/482256   Filing Date: 10/Jun/2009

Abstract:

The present invention comprises a freeze-dried, dairy or dairy-substitute composition comprising a dairy or dairy-substitute ingredient and an emulsifier and methods of using same to promote and/or improve child development.

Priority: WO2008US63312 Applic. Date: 2008-05-09

Inventor: PETERSON SCOTT [US]; WELCH FRANK [US]; BURKHOLDER THOMAS [US]; JAGER NORMAN [US]; ALEMAN GIOVANNA [US]


Application No.: US20090304964A1  Published: 10/Dec/2009

Title: Vessel Closing Laminate

Applicant/Assignee: SELIG SEALING PRODUCTS INC

Application No.: 12/227573   Filing Date: 16/Mar/2007

Abstract:

A vessel closing laminate comprising: a seal laminate (1) comprising a bottom subassembly of layers including a foil layer (5)

and a seal substrate attached to the uppermost layer of the bottom subassembly of layers wherein the seal substrate has a bottom foam layer (2) and a top plastic material layer (10) and further includes a free tab (50) lying wholly within the circumference of the seal

a wax layer (11) on top of the plastic material layer of the seal substrate

and an absorbent liner (12) adhered to the plastic layer of the seal substrate by means of the wax layer.

Priority: EP20060111411 Applic. Date: 2006-03-20; WO2007US06595 Applic. Date: 2007-03-16

Inventor: SACHS VICTOR [GB]; O'BRIEN DAVID JOHN [GB]; MCLEAN ANDREW FENWICK [GB]


Application No.: US20090305194A1  Published: 10/Dec/2009

Title: DENTAL FILLERS INCLUDING A PHOSPHORUS CONTAINING SURFACE TREATMENT, AND COMPOSITIONS AND METHODS THEREOF

Applicant/Assignee:

Application No.: 11/719475   Filing Date: 07/Nov/2005

Abstract:

The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes phosphorus and a divalent cation. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment.

Priority: US2004-989779 Applic. Date: 2004-11-16; WO2005US40343 Applic. Date: 2005-11-07

Inventor: RUSIN RICHARD P [US]; MITRA SUMITA B [US]; CUMMINGS KEVIN M [US]


Application No.: US20090305195A1  Published: 10/Dec/2009

Title: PREFORMED MALLEABLE SOLID CROWN

Applicant/Assignee:

Application No.: 12/440611   Filing Date: 10/Sep/2007

Abstract:

A solid dental crown and methods of using the solid dental crown are disclosed. The solid dental crown includes, a self-supporting solid hardenable preformed dental crown having an external crown shape defined by an external crown surface. The external crown surface defines a crown volume that is substantially filled with a hardenable composition. The hardenable composition has sufficient malleability so that the solid preformed dental crown can be pressed onto a prepared tooth surface to form a recess in the solid preformed dental crown defined by a recess surface that is complimentary to the prepared tooth surface.

Priority: US20060825482P Applic. Date: 2006-09-13; WO2007US78006 Applic. Date: 2007-09-10

Inventor: JONES TODD D [US]; KARIM NAIMUL [US]; JACOBS DWIGHT W [US]; RANDOLPH KATHLEEN A [US]


Application No.: US20090305196A1  Published: 10/Dec/2009

Title: DENTAL COMPOSITIONS INCLUDING ORGANOGELATORS, PRODUCTS, AND METHODS

Applicant/Assignee:

Application No.: 12/441011   Filing Date: 12/Sep/2007

Abstract:

A hardenable dental composition that includes a polymerizable component and an organogelator.

Priority: US20060825491P Applic. Date: 2006-09-13; WO2007US78257 Applic. Date: 2007-09-12

Inventor: KARIM NAIMUL [US]; JONES TODD D [US]; LEWANDOWSKI KEVIN M [US]; CRAIG BRADLEY D [US]; MITRA SUMITA B [US]; YANG JIE [US]


Application No.: US20090305322A1  Published: 10/Dec/2009

Title: Isotope Detection and Uses Thereof

Applicant/Assignee:

Application No.: 12/085086   Filing Date: 15/Nov/2006

Abstract:

A method is disclosed for measuring the hydrogen and/or oxygen isotope ration of intracellular water in Escherichia coli cells and correlating the hydrogen and/or oxygen isotope ratio with the metabolic activity of the cell. A method is also disclosed for measuring the hydrogen and/or oxygen ratio of intracellular water via a probe, such as a fatty acid, and correlating the hydrogen and/or oxygen ratio with the metabolic activity of the cell. Methods for measuring the hydrogen and/or oxygen isotope ratio of water from eukaryotic organisms, such as cultured rat fibroblasts and whole mammals, and optionally relating the same to a metabolic rate, are also disclosed.

Priority: US20050737614P Applic. Date: 2005-11-16; US20060851191P Applic. Date: 2006-10-12; WO2006US44263 Applic. Date: 2006-11-15

Inventor: HEGG ERIC L [US]; KREUZER-MARTIN HELEN [US]; PODLESAK DAVID WILLIAM [US]; LOTT MICHAEL J [US]


Application No.: US20090305954A1  Published: 10/Dec/2009

Title: HISTIDINE-CONTAINING DIASTEREOMERIC PEPTIDES AND USES THEREOF

Applicant/Assignee: YEDA RESEARCH AND DEVELOPMENT CO. LTD

Application No.: 12/159598   Filing Date: 27/Dec/2006

Abstract:

Diastereomeric peptides with a net positive charge greater than +1, and cyclic derivatives thereof, are provided, having at least 13 amino acid residues, comprising histidine and one or more hydrophobic amino acid residues, optionally esterified or amidated at the C-terminus and/or acylated at the N-terminus. The peptides may contain other amino acid residues including non-natural amino acids. The peptides are particularly useful in the treatment of cancer.

Priority: US20050753401P Applic. Date: 2005-12-27; WO2006IL01496 Applic. Date: 2006-12-27

Inventor: SHAI YECHIEL [IL]; MAKOVITZKI ARIK [IL]


Application No.: US20090305980A1  Published: 10/Dec/2009

Title: Methods and Compositions Related to TR4

Applicant/Assignee: UNIVERSITY OF ROCHESTER

Application No.: 12/300077   Filing Date: 09/May/2007

Abstract:

Disclosed are compositions and methods related to TR4 and cancer.

Priority: US20060798974P Applic. Date: 2006-05-09; WO2007US11159 Applic. Date: 2007-05-09

Inventor: LEE YI-FEN [US]; CHANG CHAWNSHANG [US]


Application No.: US20090306163A1  Published: 10/Dec/2009

Title: TOPICAL COMPOSITIONS COMPRISING IMIDAZOLIDINEDIONE ANALOGS AND THEIR USE TO TREAT OR PREVENT THE APPEARANCE OF SKIN WRINKLING

Applicant/Assignee:

Application No.: 12/481718   Filing Date: 10/Jun/2009

Abstract:

The described invention relates to the formulation and delivery of topical compositions comprising a cosmetically effective amount of at least one imidazolidinedione analog reduce the appearance of wrinkles.

Priority: US20080060200P Applic. Date: 2008-06-10

Inventor: LIPKIN PAMELA RENEE [US]


Application No.: US20090306216A1  Published: 10/Dec/2009

Title: Use of Beta-Aminoalcohols in the Treatment of Inflammatory Disorders and Pain

Applicant/Assignee:

Application No.: 12/282259   Filing Date: 09/Mar/2007

Abstract:

A compound for therapeutic use, of the formula (I), wherein R1 is aryl or heteroaryl optionally substituted with R5

R2 is H, alkyl or CH2OH or forms part of a ring with R4

R3 is H, alkyl or CH2OH or forms part of a ring with R4

R4 is H, alkyl or (when forming part of a ring with R2 or R3) CH2

and R5 is alkyl, CF3, OH, Oalkyl, OCOalkyl, CONH2, CN, halogen, NH2, NO2, NHCHO, NHCONH2, NHSO2Me, CONH2, or SOMe

or a salt thereof.

Priority: GB20060004822 Applic. Date: 2006-03-09; WO2007GB00816 Applic. Date: 2007-03-09

Inventor: BREW JOHN [GB]; BAXTER ANDREW DOUGLAS [GB]; BANNISTER ROBIN MARK [GB]


Application No.: US20090306506A1  Published: 10/Dec/2009

Title: Method Of Aquiring Data In The Mouth Of A Patient, Such A Device, An Arrangement Comprising A Dentist's Chair And Such A Device And The Use Of This Device

Applicant/Assignee: RHEINISCH-WESTFAELISCH-TECHNISCHE HOCHSCHULE AACHEN

Application No.: 12/301622   Filing Date: 30/May/2007

Abstract:

A device (10) for acquiring data in the mouth of a patient, wherein the device (10) comprises an ultrasound sensor (20) and a support structure. The ultrasound sensor (20) is stored by means of the support structure when not in use and contains ultrasound deflection means (12) which are movable. A coupling body (21) is provided, which is arranged between the ultrasound deflection means (12) and a tooth area (1, 2, 3) or remaining tooth area to be swept over Excitation signals (14) are sent to the ultrasound sensor (20) and the ultrasound deflection means (12) are moved in order to thus produce an ultrasonic wave which sweeps over at least part of the tooth area (1, 2, 3) or remaining tooth area.

Priority: DE200610025775 Applic. Date: 2006-05-31; WO2007EP04756 Applic. Date: 2007-05-30

Inventor: HEGER STEFAN [DE]; LATZKE PETER [DE]; RADERMACHER KLAUS [DE]; SPIEKERMANN HUBERTUS [DE]; TINSCHERT JOACHIM [DE]


Application No.: US20090311184A1  Published: 17/Dec/2009

Title: HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE-RELATED COMPOUNDS

Applicant/Assignee:

Application No.: 12/463374   Filing Date: 08/May/2009

Abstract:

The invention provides compositions of novel high penetration compositions (HPC) or high penetration prodrugs (HPP) of peptides and peptide-related compounds, which are capable of crossing biological barriers with high penetration efficiency. The HPPs are capable of being converted to parent active drugs or drug metabolites after crossing the biological barrier and thus can render treatments for the conditions that the parent drugs or metabolites can. Additionally, the HPPs are capable of reaching areas that parent drugs may not be able to access or to render a sufficient concentration at the target areas and therefore render novel treatments. The HPPs can be administered to a subject through various administration routes, e.g., locally delivered to an action site of a condition with a high concentration or systematically administered to a biological subject and enter the general circulation with a faster rate.

Priority: WO2006IB54170 Applic. Date: 2006-11-08

Inventor: YU CHONGXI [US]


Application No.: US20090311197A1  Published: 17/Dec/2009

Title: Method and Compositions for Oral Hygiene

Applicant/Assignee: IMREX, INC

Application No.: 12/509768   Filing Date: 27/Jul/2009

Abstract:

The present invention comprises novel compositions and methods for oral hygiene and for treating and preventing oral disease in humans and in animals. In one embodiment, the novel compositions of the present invention comprise a unique oral hygiene solution that can be added to drinking water. The invention provides compositions and methods for maintaining oral health that are convenient to use and are formulated so that they are safe for regular use by humans and animals.

Priority: US2004-018851 Applic. Date: 2004-12-21; US20030532303P Applic. Date: 2003-12-22

Inventor: ROMANOWSKI RADEK [CA]; EMILY PETER [US]; ALKEMADE STAN [CA]


Application No.: US20090311198A1  Published: 17/Dec/2009

Title: Perhydrolase for Tooth Whitening

Applicant/Assignee:

Application No.: 12/224535   Filing Date: 26/Feb/2007

Abstract:

The present invention provides compositions and methods for the use of perhydrolase to whiten teeth.

Priority: US20060778999P Applic. Date: 2006-03-03; WO2007US05017 Applic. Date: 2007-02-26

Inventor: CONCAR EDWARD M [US]; POULOSE AYROOKARAN J [US]


Application No.: US20090311199A1  Published: 17/Dec/2009

Title: Use of Hydrogen Peroxide-Producing Bacteria for Tooth Whitening

Applicant/Assignee: ORAGENICS, INC

Application No.: 12/482881   Filing Date: 11/Jun/2009

Abstract:

The invention provides compositions and methods for whitening teeth of a subject comprising administering one or more isolated, non-pathogenic, hydrogen peroxide-producing bacterial strains to an oral cavity of a subject.

Priority: US20080061264P Applic. Date: 2008-06-13

Inventor: HILLMAN JEFFREY DANIEL [US]


Application No.: US20090311200A1  Published: 17/Dec/2009

Title: Oral Compositions and Uses Thereof

Applicant/Assignee: COLGATE-PALMOLIVE

Application No.: 12/138647   Filing Date: 13/Jun/2008

Abstract:

The present invention is directed to a dual phase mouth wash composition comprising a hydrophilic phase, a hydrophobic phase, and a hydrotrope, and methods of use thereof. The hydrophilic and hydrophobic phases remain separated and form a temporary emulsion when mixed. The emulsion spontaneously reverts back to the two original phases after rest, without the formation of a emulsion.

Priority:

Inventor: LAMBERT PIERRE [BE]; BLANVALET CLAUDE [BE]


Application No.: US20090311201A1  Published: 17/Dec/2009

Title: LIPOXIN ANALOGS AND METHODS FOR THE TREATMENT OF PERIODONTAL DISEASE

Applicant/Assignee: TRUSTEES OF BOSTON UNIVERSITY BRIGHAM AND WOMEN'S HOSPITAL, INC UNIVERSITY OF SOUTHERN CALIFORNIA

Application No.: 12/539728   Filing Date: 12/Aug/2009

Abstract:

This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invention also provides for methods of treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease with compositions containing COX-2 inhibitors. Further, the invention provides methods for preventing systemic diseases beyond theoral cavity that are related to periodontal disease using the composition containing lipoxin analogs, COX-2 inhibitors, or both.

Priority: US2002-239444 Applic. Date: 2002-09-20; WO2001US09096 Applic. Date: 2001-03-20; US20000190656P Applic. Date: 2000-03-20

Inventor: VAN DYKE THOMAS E [US]; PETASIS NICOS A [US]; SERHAN CHARLES N [US]


Application No.: US20090311249A1  Published: 17/Dec/2009

Title: Capecitabine Combination Therapy

Applicant/Assignee:

Application No.: 12/227656   Filing Date: 04/Jun/2007

Abstract:

The invention provides the use of a combination of an mTOR inhibitor and capecitabine in the treatment of cancer.

Priority: US20060810371P Applic. Date: 2006-06-02; WO2007US13243 Applic. Date: 2007-06-04

Inventor: GIANNI LUCA [IT]; BEDROSIAN CAMILLE L [US]


Application No.: US20090311251A1  Published: 17/Dec/2009

Title: SCFV ANTIBODIES WHICH PASS EPITHELIAL AND/OR ENDOTHELIAL LAYERS

Applicant/Assignee: ESBATECH AG

Application No.: 12/307875   Filing Date: 10/Jul/2007

Abstract:

scFv antibodies which specifically bind selected antigens and are obtainable by a method comprising (i) selecting from a pool of soluble and stable antibody frameworks a soluble and stable framework matching best the framework of a non-human antibody against the antigen with a certain binding specificity, (ii) either providing said soluble and stable framework with CDRs that bind specifically to said antigen, or mutating the framework of said non-human antibody towards the sequence of said soluble and stable framework, to generate scFv antibodies, (iii) testing the generated antibody for solubility and stability, and testing the generated antibody for antigen binding, and (iv) selecting an scFV that is soluble, stable and binds to the antigen specifically. Also provided are pharmaceutical compositions comprising said scFv antibody, methods of treatment and diagnosis for diseases related to over expression of antigens that are specifically bound by said antibody.

Priority: US20060819378P Applic. Date: 2006-07-10; US20070899907P Applic. Date: 2007-02-06; WO2007CH00334 Applic. Date: 2007-07-10

Inventor: AUF DER MAUR ADRIAN [CH]; BARBERIS ALCIDE [CH]; URECH DAVID M [CH]; LICHTLEN PETER [CH]


Application No.: US20090311262A1  Published: 17/Dec/2009

Title: Method for Diagnosing Cancers Expressing the HER2 Receptor or its Truncated Variants

Applicant/Assignee: FUNDACIO PRIVADA INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL HEBRON FUNDACIO PRIVADA INSTITUCIO CATALANA DE RECERCA IESTUDIS AVANCATS FUNDACIO PRIVADA INSTITUT D'INVESTIGACIO ONCOLOGICA DE VALL HEBRON

Application No.: 12/479035   Filing Date: 05/Jun/2009

Abstract:

The present invention relates to a method of diagnosis and therapy of cancers expressing the HER2 receptor. The invention provides antibodies or fragments thereof that recognises an epitope of a HER2 receptor truncated form, said epitope being defined by a sequence included in SEQ ID NO: 2. The invention also provides a method of cancer diagnosis, which comprises the detection of the presence of the HER2 receptor truncated form consisting of the amino acid sequence SEQ ID NO: 1 in a patient sample.

Priority: ES20080001652 Applic. Date: 2008-06-02

Inventor: ARRIBAS LOPEZ JOAQUIN [ES]; PEDERSEN KIM [ES]; ANGELLINI PIER-DAVIDE [ES]; PARRA PALAU JOSEP LIUIS [ES]; LAOS SIRLE [ES]; BASELGA TORRES JOSE [ES]


Application No.: US20090311284A1  Published: 17/Dec/2009

Title: Recombinant Viral Proteins And Particles

Applicant/Assignee: ACADEMIA SINICA

Application No.: 12/522009   Filing Date: 20/Sep/2007

Abstract:

Disclosed are nucleic acids encoding fusion polypeptides containing the sequence of a Bamboo mosaic virus coat protein or a segment thereof

and an immunogenic heterologous fragment that is fused to the carrier fragment. Also disclosed are related chimeric bamboo mosaic virus particle, related expression vectors, related host cells, and related compositions. Methods of producing and using the fusion polypeptide or chimeric Bamboo mosaic virus particle are also disclosed.

Priority: EP20070100073 Applic. Date: 2007-01-03; WO2007US79060 Applic. Date: 2007-09-20

Inventor: LIANG SHU-MEI [TW]; LIN NA-SHENG [TW]; HSU YAU-HEIU [TW]; LIAO JIA-TEH [TW]


Application No.: US20090311294A1  Published: 17/Dec/2009

Title: ACTIVE DELIVERY ORAL CARE IMPLEMENT

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/145775   Filing Date: 25/Jun/2008

Abstract:

An oral care implement includes a head (12), a handle (10), a neck portion (11) connecting the head and the handle, and a reservoir (15) located in the neck portion which contains at least one active agent. The implement has an activator (22) for activating a delivery device which delivers the active agent to one or more outlets (50). A wide variety of types of active agents may be administered at appropriate and accurate doses for therapeutic, hygienic, and/or other benefit.

Priority: WO2008US66828 Applic. Date: 2008-06-13

Inventor: GATZEMEYER JOHN [US]


Application No.: US20090311347A1  Published: 17/Dec/2009

Title: COMBINATION THERAPY FOR BIPOLAR DISORDER

Applicant/Assignee:

Application No.: 12/422156   Filing Date: 10/Apr/2009

Abstract:

Treatment regimens for mood disorders that include administration of buprenorphine, alone or in combination with additional pharmacological agents are described. Specifically, treatment regimens that alleviate racing thoughts associated with bipolar disorder, and pharmaceutical compositions and kits for use therein are described. Dosing regimens, compositions, and kits including buprenorphine for treating mania associated with opioid withdrawal are also described.

Priority: US20080044312P Applic. Date: 2008-04-11; US20080050738P Applic. Date: 2008-05-06

Inventor: ORONSKY BRYAN T [US]; ORONSKY NEIL C [US]


Application No.: US20090311421A1  Published: 17/Dec/2009

Title: DEVICE AND PROCESS FOR VARNISHING METALLIC ELEMENTS

Applicant/Assignee:

Application No.: 11/995972   Filing Date: 07/Dec/2005

Abstract:

The device for varnishing metallic elements (1) comprises support means of the metallic elements (1) to be varnished through powdered varnish and dispensing means of the powdered varnish through a screen printing plate (5), foreseeing rotation means (6) of the screen printing plate about a rotation axis and translation means (7) of the rotation means (6) to give said screen printing plate (5) a roto-translation motion with respect to the metallic elements (1) to be varnished. The process for varnishing metallic elements through powdered varnish consists of keeping each metallic element in suspended position during the deposition on one or more of its faces of at least one layer of powdered varnish after having been made to pass through a screen printing plate.

Priority: IT2005MI01388 Applic. Date: 2005-07-20; WO2005EP13101 Applic. Date: 2005-12-07

Inventor: TREVISAN SILVIO MARIA [IT]


Application No.: US20090311645A1  Published: 17/Dec/2009

Title: Dental appliance

Applicant/Assignee:

Application No.: 12/157670   Filing Date: 12/Jun/2008

Abstract:

Embodiments include dental appliances, dental appliance systems, and methods of making and using such appliances. In one embodiment, a dental appliance includes a shell having a number of cavities to receive one or more teeth, each cavity having an inner surface. Fewer than all cavities are scaled-up in size by a first selected percentage over one or more dimensions of a corresponding tooth surface to provide a uniform space between the cavity inner surface and the corresponding tooth surface.

Priority:

Inventor: MATTY RICK M [US]; MOREFIELD ANTHONY W [US]; WEBB DEVIN K [US]


Application No.: US20090311650A1  Published: 17/Dec/2009

Title: Method for the production of a ceramic molded part

Applicant/Assignee:

Application No.: 12/310998   Filing Date: 04/Oct/2007

Abstract:

A process for the preparation of a ceramic molded part from a suspension/dispersion with a solids content and a fluid content by depositing solids content at the periphery of a porous self-supporting support that is at least partially immersed in the suspension/dispersion and has the same shape as the molded part to be prepared, but with a reduced size, wherein: the solids content contains oxide-ceramic particles

the porous self-supporting support is detachably connected with a discharge in a zone that is not immersed in the suspension/dispersion

the suspension/dispersion is moved towards the porous self-supporting support by means of a positive pressure difference between a pressure prevailing in the suspension/dispersion and a pressure prevailing in the discharge

wherein the fluid content of the suspension/dispersion enters in the porous self-supporting support with depositing solids content at the periphery of the porous self-supporting support.

Priority: EP20060020897 Applic. Date: 2006-10-05; WO2007EP60546 Applic. Date: 2007-10-04

Inventor: STEPHAN MARC [DE]; THIEL NORBERT [DE]; BOJEMUELLER ENNO [DE]


Application No.: US20090312320A1  Published: 17/Dec/2009

Title: METHODS OF TREATMENT COMPRISING THE ADMINISTRATION OF HALOARYL SUBSTITUTED AMINOPURINES OR COMPOSITIONS THEREOF

Applicant/Assignee: SIGNAL PHARMACEUTICALS, LLC

Application No.: 12/540013   Filing Date: 12/Aug/2009

Abstract:

Provided herein are Aminopurine Compounds having the following structure: wherein R1, R2 and and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.

Priority: US2006-332617 Applic. Date: 2006-01-12; US20050643796P Applic. Date: 2005-01-13; US20050709980P Applic. Date: 2005-08-19

Inventor: ALBERS RONALD J [US]; AYALA LETICIA [US]; CLAREEN STEVEN S [US]; DELGADO MEDEROS MARIA MERCEDES [US]; HILGRAF ROBERT [US]; HEGDE SAYEE G [US]; HUGHES KEVIN [US]; KOIS ADAM [US]; PLANTEVIN-KRENITSKY VERONIQUE [US]; MCCARRICK MEG [US]; NADOLNY LISA [US]; PALANKI MOORTHY S S [US]; SAHASRABUDHE KIRAN [US]; SAPIENZA JOHN [US]; SATOH YOSHITAKA [US]; SLOSS MARIANNE K [US]; SUDBECK ELISE [US]; WRIGHT JONATHAN [US]; HENDERSON IAN [US]; COLE ANDREW G [US]


Application No.: US20090312342A1  Published: 17/Dec/2009

Title: Quinazolines useful as modulators of ion channels

Applicant/Assignee:

Application No.: 11/367954   Filing Date: 03/Mar/2006

Abstract:

The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Priority: US2005-216376 Applic. Date: 2005-08-31; US20040607150P Applic. Date: 2004-09-02; US20040607037P Applic. Date: 2004-09-02; US20040607033P Applic. Date: 2004-09-02; US20040607036P Applic. Date: 2004-09-02

Inventor: WILSON DEAN [US]; TERMIN ANDREAS [US]; GONZALEZ JESUS [US]; FANNING LEV [US]; NEUBERT TIMOTHY [US]; KRENITSKY PAUL [US]; JOSHI PRAMOD [US]; HURLEY DENNIS [US]; SHETH URVI [US]


Application No.: US20090312364A1  Published: 17/Dec/2009

Title: NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS

Applicant/Assignee: NEUROSEARCH A/S

Application No.: 12/520239   Filing Date: 18/Dec/2007

Abstract:

This invention relates to novel chromen-2-one derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20060001679 Applic. Date: 2006-12-20; US20060875805P Applic. Date: 2006-12-20; WO2007EP64131 Applic. Date: 2007-12-18

Inventor: PETERS DAN [SE]; REDROBE JOHN PAUL [DK]; OLSON GUNNAR M [DK]; NIELSEN ELSEBET OSTERGAARD [DK]


Application No.: US20090312384A1  Published: 17/Dec/2009

Title: Benzimidazole As Cooling Compounds

Applicant/Assignee:

Application No.: 12/307835   Filing Date: 16/Jul/2007

Abstract:

A method of providing a cooling sensation to the skin or mucous membranes of the mouth by applying thereto a quantity of at least one chemical compound sufficient to cause a desirable degree of cooling sensation, the chemical compound comprising a compound of formula I: in which R1, R2 are independently in either the meta- or para-position and independently comprise at least one of hydrogen, halide, C1-C3 alkyl (linear or branched), halide, C1-C3 alkoxy, nitro, nitrile, amide or ester

R3 comprises at least one of C1-C5 alkyl or C1-C5 alkenyl groups (linear or branched), R4 comprises at least one of hydrogen, C1-C3 alkyl (linear or branched), or a halide. The cooling effect provided is in some instances superior to that achievable by any of the known commercial cooling agents.

Priority: US20060830964P Applic. Date: 2006-07-14; WO2007CH00340 Applic. Date: 2007-07-16

Inventor: FURRER STEFAN MICHAEL [US]; BELL KAREN ANN [US]; GALOPIN CHRISTOPHE C [US]; MCCLUSKEY THOMAS SCOTT [US]; SLACK JAY PATRICK [US]


Application No.: US20090312420A1  Published: 17/Dec/2009

Title: Production Of Peracids Using An Enzyme Having Perhydrolysis Activity

Applicant/Assignee:

Application No.: 12/497348   Filing Date: 02/Jul/2009

Abstract:

A process is provided for producing peroxycarboxylic acids from carboxylic acid esters. More specifically, carboxylic acid esters are reacted with an inorganic peroxide, such as hydrogen peroxide, in the presence of an enzyme catalyst having perhydrolysis activity. The present perhydrolase catalysts are classified as members of the carbohydrate esterase family 7 (CE-7) based on the conserved structural features. Further, disinfectant formulations comprising the peracids produced by the processes described herein are provided.

Priority: US2007-743354 Applic. Date: 2007-05-02; US2006-638635 Applic. Date: 2006-12-12; US20050750092P Applic. Date: 2005-12-13; US20060853065P Applic. Date: 2006-10-20

Inventor: DICOSIMO ROBERT [US]; GAVAGAN JOHN E [US]; PAYNE MARK S [US]; COOLING III FREDERICK B [US]


Application No.: US20090313777A1  Published: 24/Dec/2009

Title: Oral Care Implement Having Tissue Cleaning Elements With Directional Cleaning

Applicant/Assignee: COLGATE-PALMOLIVE

Application No.: 12/142963   Filing Date: 20/Jun/2008

Abstract:

An oral care implement or toothbrush 100 includes a head 104, a tooth cleaning element region 116 and a tissue cleaning element region 114. The tissue cleaning element region 114 includes a plurality of flexible, angled projections 120. The projections 120 are configured to flex from an at-rest position to a substantially flat position when the tissue cleaning element region 114 is in contact with the tongue and is pushed into the mouth. The projections 120 are also configured to flex to a substantially upright position when the tissue cleaning element region 114 is in contact with the tongue and is pulled out of the mouth. This arrangement aids in preventing debris from being pushed into the mouth and in removing debris from the mouth and tongue. The flexible projections 120 may be used in conjunction with rigid projections 122 having a generally vertical configuration to aid in removing debris from the mouth and in engaging the cheek to improve saliva production during brushing.

Priority:

Inventor: BOYD THOMAS [US]; HOHLBEIN DOUGLAS [US]; VAZQUEZ JOE [US]; NICHOLSON IAN [US]


Application No.: US20090314385A1  Published: 24/Dec/2009

Title: Open Jet Filling System

Applicant/Assignee: KRONES AG

Application No.: 12/479897   Filing Date: 08/Jun/2009

Abstract:

An open-jet filling system, a method of filling containers by means of such an open-jet filling system used for contactless filling a container, and a corresponding filling machine, with the open-jet filling system provided with a filling level probe. For always obtaining the same filling height in the containers and for simultaneously realizing hygienic filling, a centering unit is arranged below the open-jet filling element in a vertically movable manner such that it can be moved onto a container mouth, the filling level probe being arranged on the centering unit.

Priority: DE200810029208 Applic. Date: 2008-06-19

Inventor: GOLDBRUNNER CHRISTIAN [DE]


Application No.: US20090317446A1  Published: 24/Dec/2009

Title: Calcium Phosphate Nanofibers

Applicant/Assignee: CORNELL RESEARCH FOUNDATION, INC

Application No.: 12/439398   Filing Date: 04/Sep/2007

Abstract:

Calcium-phosphate nanofiber matrices comprising randomly dispersed crystalline calcium-phosphate nanofibers are provided. The nanofibers are synthesized using sol-gel methods combined with electrospinning. The nanofibers may be hollow, solid or may comprise a calcium-phosphate shell surrounding a polymer containing inner core to which biologically functional additives may be added. The nanofiber matrices may be used to culture bone and dental cells, and as implants to treat bone, dental or periodontal diseases and defects.

Priority: US20060824377P Applic. Date: 2006-09-01; WO2007US77560 Applic. Date: 2007-09-04

Inventor: TAN JIAN [US]; JOO YONG L [US]


Application No.: US20090317461A1  Published: 24/Dec/2009

Title: ORAL COMPOSITIONS EFFECTIVE FOR THE TREATMENT OF ORAL CAVITY MALODOR ASSOCIATED WITH THE CONSUMPTION OF ODOR-CAUSING COMPOUNDS

Applicant/Assignee: WM. WRIGLEY JR. COMPANY

Application No.: 12/375751   Filing Date: 27/Jul/2007

Abstract:

This invention generally relates to oral compositions (e.g., a confection or chewing gum product) effective for the treatment of oral cavity malodor caused by odor-causing compounds (e.g., diallyl disulfide) associated with the consumption of, for example, garlic and/or onion. In particular, this invention relates to oral compositions containing menthone, isomenthone and, optionally, caryophyllene in varying concentrations, to provide an oral composition effective for the treatment of oral cavity malodor caused by odor-causing compounds associated with the consumption of, for example, garlic and onion.

Priority: US20060821175P Applic. Date: 2006-08-02; WO2007US74624 Applic. Date: 2007-07-27

Inventor: BAZEMORE RUSSELL A [US]; HARRISON CHARLES J [US]


Application No.: US20090317761A1  Published: 24/Dec/2009

Title: Stabilizer for tooth prostheses

Applicant/Assignee:

Application No.: 12/456397   Filing Date: 16/Jun/2009

Abstract:

A stabilizer for tooth prostheses, consisting of a double torsion spring, the arms (4, 5) of which are telescopically longitudinally movable in cylindrical guides (7, 8) in the prosthesis halves (1, 2), has a hook-shaped eyelet (9) on each of the ends of both of the stabilizer arms. The guides (7, 8) are closed on their external insertion ends, except for a narrow insertion slot (15) in the form of a mailbox slot, in the assembled functional position of the stabilizer in the prosthesis parts, the eyelets (9) and the eyelet planes and accordingly the planes of the stabilizer arms are directed perpendicular to the longitudinal extension of the insertion slot (15). It is thereby achieved that the stabilizers (3) or their arms cannot slip out of the guides (7, 8) and overall their assembly and disassembly can be easily and rapidly undertaken without the aid of any tools.

Priority: DE200810029086 Applic. Date: 2008-06-20

Inventor: VAN DER VEKEN PIETER [BE]; VANDER KERKEN ANDRE JOZEF ERNE [BE]


Application No.: US20090317766A1  Published: 24/Dec/2009

Title: Structured coatings for implants and process for the preparation thereof

Applicant/Assignee:

Application No.: 12/310499   Filing Date: 31/Aug/2007

Abstract:

The invention relates to a method for producing a powder-filled ceramic coating made from a precursor ceramic compound (for example, a sol-gel), said coating having an advantageous surface roughness and wherein active ingredients may be eluted from the matrix or filler under physiological conditions and to an implant which can be produced according to the claimed method.

Priority: DE200610041023 Applic. Date: 2006-09-01; WO2007EP59115 Applic. Date: 2007-08-31

Inventor: HEIDENAU FRANK [DE]; ZIEGLER GUNTER [DE]


Application No.: US20090317772A1  Published: 24/Dec/2009

Title: DENTAL COMPOSITIONS WITH CALCIUM PHOSPHORUS RELEASING GLASS

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/719466   Filing Date: 07/Nov/2005

Abstract:

The present application provides dental compositions, and methods of making and using dental compositions that include a calcium and phosphorus releasing glass. Such dental compositions can be useful for delivering ions to the oral environment.

Priority: US20040628336P Applic. Date: 2004-11-16; WO2005US40286 Applic. Date: 2005-11-07

Inventor: RUSIN RICHARD P [US]; CUMMINGS KEVIN M [US]; MITRA SUMITA B [US]; BURGIO PAUL A [US]; TZOU TSI-ZONG [US]; ARNEY DAVID S [US]


Application No.: US20090318411A1  Published: 24/Dec/2009

Title: PURINE PI3K INHIBITOR COMPOUNDS AND METHODS OF USE

Applicant/Assignee: GENENTECH, INC

Application No.: 12/474613   Filing Date: 29/May/2009

Abstract:

Purine compounds of Formula I, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including p110 alpha and other isoforms of PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Priority: US20080057559P Applic. Date: 2008-05-30

Inventor: CASTANEDO GEORGETTE [US]; CHUCKOWREE IRINA [CH]; FOLKES ADRIAN [CH]; SUTHERLIN DANIEL P [US]; WAN NAN CHI [CH]


Application No.: US20090318425A1  Published: 24/Dec/2009

Title: APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS

Applicant/Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Application No.: 12/490074   Filing Date: 23/Jun/2009

Abstract:

The present invention relates to apoptosis signal-regulating kinase 1 ("ASK1") inhibiting compounds of the formula wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds

methods and intermediates useful for making the compounds

and methods of using said compounds.

Priority: US20080075121P Applic. Date: 2008-06-24

Inventor: CHANG EDCON [US]; GWALTNEY STEPHEN L [US]; VASSAR ANGIE [US]


Application No.: US20090318430A1  Published: 24/Dec/2009

Title: MEDICAL USE OF CYCLIN DEPENDENT KINASES INHIBITORS

Applicant/Assignee: ASTEX THERAPEUTICS LIMITED

Application No.: 12/374461   Filing Date: 20/Jul/2007

Abstract:

The invention provides the use of a compound for the manufacture of a medicament for the treatment of pain, wherein the compound is a compound of the formula (0): or a salt or tautomers or N-oxides or solvate thereof

wherein X is a group R1-A-NR4- or a 5- or 6-membered carbocyclic or heterocyclic ring

A is a bond, SO2, C-O, NRg(C-O) or O(C-O) wherein Rg is hydrogen or C1-4 hydrocarbyl optionally substituted by hydroxy or C1-4 alkoxy

Y is a bond or an alkylene chain of 1, 2 or 3 carbon atoms in length

R1 is hydrogen

a carbocyclic or heterocyclic group having from 3 to 12 ring members

or a C1-8 hydrocarbyl group optionally substituted by one or more substituents selected from halogen, hydroxy, C1-4 hydrocarbyloxy, amino, mono- or di-C1-4 hydrocarbylamino, and carbocyclic or heterocyclic groups having from 3 to 12 ring members, and wherein 1 or 2 of the carbon atoms of the hydrocarbyl group may optionally be replaced by an atom or group selected from O, S, NH, SO, SO2

R2 is hydrogen

halogen

C1-4 alkoxy

or a C1-4 hydrocarbyl group optionally substituted by halogen, hydroxyl or C1-4 alkoxy (e.g. methoxy)

R3 is selected from hydrogen and carbocyclic and heterocyclic groups having from 3 to 12 ring members

and R4 is hydrogen or a C1-4 hydrocarbyl group optionally substituted by halogen (e.g. fluorine), hydroxyl or C1-4 alkoxy. The invention also provides the use of the compounds of the formula (0) for the treatment of stroke and for the treatment of polycystic kidney disease.

Priority: US20060832678P Applic. Date: 2006-07-21; WO2007GB02753 Applic. Date: 2007-07-20

Inventor: PIKE ANDREW [GB]; LYONS JOHN FRANCIS [GB]


Application No.: US20090320765A1  Published: 31/Dec/2009

Title: Top-fill hummingbird feeder with vertically operative base sealing mechanism

Applicant/Assignee:

Application No.: 12/213924   Filing Date: 26/Jun/2008

Abstract:

A top-fill hummingbird feeder has a generally upstanding reservoir bottle or liquid container with a large opening at its top end that is closed and sealed by a removable top or cap. The bottom of the bottle or container has a lower bottom opening which can be screw-threaded into a central collar of a feeding basin that has a plurality of feeding ports. A tubular insert is received within the central collar and is configured to be vertically movable between a first position in which fluid is allowed to flow from the liquid container to the basin, and a second position in which fluid flow from the container to the basin is prevented. Movement of the insert between the two positions is effected by pushing the liquid container toward the basin (the closed position) and by pulling the liquid container away from the basin (the open position). Each movement of the insert has an associated "snap" or gives positive physical feedback which the user can feel that assures the user that the desired fluid flow or fluid sealed position has been achieved.

Priority:

Inventor: GAUKER ANDREW [US]; LUBIC MARKO KONSTANTIN [US]; VAUGHN JR WILLIAM R [US]


Application No.: US20090320849A1  Published: 31/Dec/2009

Title: Anti-Viral Face Mask and Filter Material

Applicant/Assignee:

Application No.: 12/374104   Filing Date: 16/Jul/2007

Abstract:

A face mask comprising a filter material being a fibrous substrate, especially non-woven polypropylene or polyester, having an acidic polymer, especially of the Carbopol or Gantres type, deposited on the fibres. The mask has an anti-viral activity against inhaled or exhaled air. A filter material suitable for such a mask, and a process for making it are also described.

Priority: GB20060014251 Applic. Date: 2006-07-18; GB20070006435 Applic. Date: 2007-04-02; WO2007EP57298 Applic. Date: 2007-07-16

Inventor: BIEDERMANN KIMBERLY [US]


Application No.: US20090321971A1  Published: 31/Dec/2009

Title: Methods of Manufacturing Dental Restorations Using Nanocrystalline Materials

Applicant/Assignee: PENTRON CERAMICS, INC

Application No.: 12/490539   Filing Date: 24/Jun/2009

Abstract:

Dental articles are produced using relatively low sintering temperatures to achieve high density dental articles exhibiting strengths equal to and greater than about 700 MPa. Ceramic powders comprised of nanoparticulate crystallites are used to manufacture dental articles. The ceramic powders may include sintering agents, binders and other similar additives to aid in the processing of the ceramic powder into a dental article. The ceramic powders may be processed into dental articles using various methods including, but not limited to, injection molding, gel-casting, slip casting, or electroforming, hand, cad/camming and other various rapid prototyping methods. The ceramic powder may be formed into a suspension, pellet, feedstock material or a pre-sintered blank prior to forming into the dental article.

Priority: US2004-857482 Applic. Date: 2004-05-28; US20030474166P Applic. Date: 2003-05-29

Inventor: BRODKIN DMITRI [US]; GAMARNIK MOISEY Y [US]


Application No.: US20090324513A1  Published: 31/Dec/2009

Title: Process for Producing Chlorinated Sucrose

Applicant/Assignee: PHARMED MEDICARE PRIVATE LIMITED

Application No.: 10/593158   Filing Date: 20/May/2004

Abstract:

Present invention relates to disclosure of application of some innovative techniques useful for substantially improving process efficiency of production of chlorinated sucrose including their intermediates and derivatives. Application of mild methods of drying has been made for recovery of chlorinated sucrose or their intermediates and derivatives, in substantially pure form or with other solid chemical impurities, obtained at various stages in the process of production of chlorinated sucrose. Mild methods of drying included agitated thin film drying, spray drying, freeze drying and super critical extraction. Use of alkoxides has been introduced for deacylation instead of alkali hydroxides or alkaline earth hydroxides. Deacylation has been shown to be effective both, either before or after drying of the reaction mixture. Extraction and purification of desired products i.e. of chlorinated sucrose or its intermediates or derivatives, from dried solid mixtures could be achieved by using appropriate extraction method, including but not limited to solvent extraction and super critical extraction. Further purification of such extracts can be done by crystallization or direct drying under mild conditions.

Priority: WO2004IN00064 Applic. Date: 2004-03-19; IN2004MU00563 Applic. Date: 2004-05-17; WO2004IN00142 Applic. Date: 2004-05-20

Inventor: RATNAM RAKESH [IN]; KULKARNI SHRIKANT [IN]; AURORA SUNEET [IN]


Application No.: US20090324514A1  Published: 31/Dec/2009

Title: Methods and composition for treating a material

Applicant/Assignee: URTHTECH, LLC

Application No.: 12/387120   Filing Date: 28/Apr/2009

Abstract:

A composition and method are described for sanitizing or otherwise treating a material such as a non-living surface, living tissue, soil or atmosphere which may be contaminated by a toxin, chemical warfare agent, insect, prion, microorganism or other infectious agent. The composition generally includes an aqueous composition mixture that includes: (a) lower alkanol

(b) an alkalinating agent, and (c) a fatty acid salt and/or ester. The components are present in an effective amount to sanitize (or treat) a material (or modifying a chemical contained thereon) to which the composition is applied. Also described are methods of making the composition.

Priority: US2009-380077 Applic. Date: 2009-02-23; US2006-486736 Applic. Date: 2006-07-14

Inventor: AWAD AZIZ C [US]


Application No.: US20090324516A1  Published: 31/Dec/2009

Title: Composition and Method for Enhancing Flouride Uptake Using Bioactive Glass

Applicant/Assignee:

Application No.: 12/492302   Filing Date: 26/Jun/2009

Abstract:

A method for increasing fluoride uptake onto a tooth structure of a patient comprises contacting the tooth structure with an oral care composition, which comprises bioactive glass and fluoride. The oral care composition has the following formulation: Ingredient Weight Percent Glycerin 0-90 PEG 0-40 Abrasive 0-30 Thickening Agent 0.1-10 Bioactive glass 0.5-15 Surfactant 0-10 Colorant 0-2.0 Flavor 0.1-2.0 Fluoride 0-5.0 Gum Binder 0-2.0 Sweetener 0-1.0 Colophony Resin 0-75 Ethyl Alcohol 0-25

Priority: US20080076210P Applic. Date: 2008-06-27

Inventor: MUSCLE DAVE P [US]; BURWELL ANORA K [US]; LATORRE GAETANO [US]


Application No.: US20090324545A1  Published: 31/Dec/2009

Title: POLYMORPHIC FORMS OF (S)-1-TETRAHYDROFURAN-3-YL-3-(3-(3-METHOXY-4-(OXAZOL-5-YL)PHENYL)UREIDO)BENZYL CARBAMATE

Applicant/Assignee: VERTEX PHARMACEUTICALS INCORPORATED

Application No.: 12/555203   Filing Date: 08/Sep/2009

Abstract:

The present invention relates to polymorphic forms of (S)-tetrahydrofuran-3-yl 3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)benzylcarbamate, processes therein, pharmaceutical compositions thereof, and uses therewith.

Priority: US2006-429811 Applic. Date: 2006-05-08; US20050679021P Applic. Date: 2005-05-09

Inventor: BLYTHE TODD [US]; EBERLIN ALEX [GB]; HURREY MICHAEL [US]; JONAITIS DAVID [US]; NYCE PHILIP [US]; PARENT STEPHAN [US]; SNOONIAN JOHN [US]


Application No.: US20090324555A1  Published: 31/Dec/2009

Title: Neural Stem Cells

Applicant/Assignee: STIFTUNG CAESAR

Application No.: 11/909188   Filing Date: 23/Mar/2006

Abstract:

Subject of the invention is a method for generating neural stem cells in vitro, wherein dental progenitor cells are isolated from soft tissue of tooth or wisdom tooth and cultivated until they form primary spheres which are then dissociated into single cells. These single cells are cultivated until they form spheroids and the spheroid-forming cells are separated to obtain neural stem cells.

Priority: EP20050102356 Applic. Date: 2005-03-23; WO2006EP02694 Applic. Date: 2006-03-23

Inventor: THIE MICHAEL [DE]; DEGISTIRICI OEZER [DE]


Application No.: US20090324577A1  Published: 31/Dec/2009

Title: 6-11 Bicyclic Ketolide Derivatives

Applicant/Assignee:

Application No.: 12/493847   Filing Date: 29/Jun/2009

Abstract:

The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

Priority: US2007-758225 Applic. Date: 2007-06-05; US2005-042720 Applic. Date: 2005-01-25; US2003-717290 Applic. Date: 2003-11-19; US2003-429485 Applic. Date: 2003-05-05; US2002-144558 Applic. Date: 2002-05-13

Inventor: OR YAT SUN [US]; GUOQIANG WANG [US]; PHAN LY TAM [US]; NIU DEQIANG [US]; VO NHA HUU [US]; QIU YAO-LING [US]; WANG YANCHUN [US]; BUSUYEK MARINA [US]; HOU YING [US]; PENG YULIN [US]; KIM HEEJIN [US]; LIU TONGZHU [US]; FARMER JAY JUDSON [US]; XU GUOYOU [US]


Application No.: US20090324584A1  Published: 31/Dec/2009

Title: Nucleic Acid of Formula (I): GIXmGn, or (II): CIXmCn, in Particular as an Immune-Stimulating Agent/Adjuvant

Applicant/Assignee: CUREVAC GMBH

Application No.: 12/375178   Filing Date: 31/Jul/2007

Abstract:

The present invention relates to a nucleic acid of the general formula (I): GlXmGn, or (II): ClXmCn, which may be modified by a lipid. The nucleic acid of the invention acts as an immune-stimulating agent inducing the innate immune response. The invention relates further to a pharmaceutical composition (in a first embodiment), each containing an immune-stimulating agent according to the invention in combination with a pharmaceutically active carrier/vehicle (and, optionally, further auxiliary substances, additives and/or further adjuvants). In another embodiment, the inventive nucleic acid is combined with at least one pharmaceutically active component, a pharmaceutically acceptable carrier/vehicle (and, optionally, further auxiliary substances, additives and/or further adjuvants). Accordingly, the present invention is directed to a vaccine, which corresponds to a pharmaceutical composition of the invention (second embodiment), wherein the pharmaceutically active component induces a specific immune response (e.g. an antigen). The present invention relates likewise to the use of a nucleic acid of the invention or a pharmaceutical composition according to the invention for the treatment of infectious diseases, autoimmune diseases, allergies or cancer diseases.

Priority: DE200610035618 Applic. Date: 2006-07-31; WO2007EP06772 Applic. Date: 2007-07-31

Inventor: HOERR INGMAR [DE]; PROBST JOCHEN [DE]; KETTERER THOMAS [DE]; SCHEEL BIRGIT [DE]


Application No.: US20090324623A1  Published: 31/Dec/2009

Title: Two-component genome flavivirus and uses thereof

Applicant/Assignee:

Application No.: 12/151491   Filing Date: 07/May/2008

Abstract:

The present invention discloses a two-component genome flavivirus and a method for propagating such virus. Since the genetic material of this flavivirus is distributed between two genomes, the flavivirus is deficient in replication, incapable of causing disease but capable of inducing an immune response. Nevertheless, the design of the replication deficient flavivirus discussed herein allows propagation of these flaviviruses at industrial level.

Priority: US20070927993P Applic. Date: 2007-05-07

Inventor: FROLOV ILYA V [US]; SHUSTOV ALEXANDR V [US]


Application No.: US20090324662A1  Published: 31/Dec/2009

Title: Dental appliance, oral care product and method of preventing dental disease

Applicant/Assignee: CAMBRA LLC DBA ORAL BIO TECH

Application No.: 12/456849   Filing Date: 23/Jun/2009

Abstract:

A method for reducing dental disease in a patient comprises a patient wearing in the patient's mouth an appliance containing an oral care product comprising a carrier and an anti-dental disease agent with a pH above 7.0. The appliance brings the patient's teeth in direct and sustained contact with the product and is custom made for each individual patient. The oral care product is specifically prescribed and formulated for the particular dental disease of that individual patient.

Priority: US20080133098P Applic. Date: 2008-06-24

Inventor: KUTSCH V KIM [US]; BOWERS ROBERT J [US]; MILICICH GRAEME [NZ]; DROESCH JESSE L [US]


Application No.: US20090324668A1  Published: 31/Dec/2009

Title: IMPLANT, ITS USES AND METHODS FOR MAKING IT

Applicant/Assignee:

Application No.: 12/306722   Filing Date: 26/Jun/2007

Abstract:

An implant containing a source of oxygen capable of releasing oxygen in the form of molecular oxygen or reactive oxygen species, and a material selected from the group consisting of biodegradable and/or bioactive glass, sol-gel produced silica and mixtures thereof. Also disclosed are uses of the implant and methods of making it.

Priority: US20060816860P Applic. Date: 2006-06-28; WO2007FI00178 Applic. Date: 2007-06-26

Inventor: KANGASNIEMI ILKKA [FI]; PELTOLA TIMO [FI]; SALONEN JUKKA [FI]


Application No.: US20090325129A1  Published: 31/Dec/2009

Title: Moldable tray, system, and method for whitening teeth

Applicant/Assignee:

Application No.: 12/385589   Filing Date: 13/Apr/2009

Abstract:

Tooth whitening system includes a moldable dental tray of sufficiently moldable material so that a user can form the tray to substantially match the configuration of the user's teeth, in use. Moldable dental tray includes a raised region and a valley that are adjacent to and free of contact with a corresponding raised region and valley of a user's tooth adjacent a user's gum line. Thus, a tooth provided on the moldable dental tray is free of contact with the user's gingiva, in use. Tooth whitener includes a carrier, a whitening agent, and a sufficiently adhesive so that both the tooth whitener and the moldable dental tray are adhered to a user's tooth for a sufficiently long period of time to achieve a whitening of the user's tooth by the whitening agent. Tooth whitener and tray can be made of organic, natural materials.

Priority: WO2006US40021 Applic. Date: 2006-10-12

Inventor: BROWN DAMON J [US]; PHILP JR GRAHAM K [US]; PARISH-PHILP GRAHAM K [US]


Application No.: US20090325861A1  Published: 31/Dec/2009

Title: DRY WOUND DRESSING AND DRUG DELIVERY SYSTEM

Applicant/Assignee: REXADERM ,INC

Application No.: 12/439197   Filing Date: 28/Aug/2007

Abstract:

Dry dressings incorporate drug-delivery systems for anti-infective agents, growth factors, fibronectin or other substances to enhance tissue healing. A pharmaceutical composition includes hyaluronate polyvinylpyrrolidone (PVP), maltodextrin, and hydroxyethylcellulose and glycerin in the form of a membranous, wafer-like material after being freeze-dried.

Priority: US20060840265P Applic. Date: 2006-08-28; WO2007US77014 Applic. Date: 2007-08-28

Inventor: GOODHEART CLYDE R [US]


Application No.: US20090325906A1  Published: 31/Dec/2009

Title: Methods and compositions for therapeutic treatment

Applicant/Assignee:

Application No.: 12/459178   Filing Date: 26/Jun/2009

Abstract:

Methods and compositions are described for the modulation of hyperglycemia and/or one or more symptoms of hyperglycemia. Methods and compositions are described for the modulation of efflux transporter activity to increase the efflux of calcineurin inhibitors out of a physiological compartment and into an external environment. In particular, the methods and compositions disclosed herein provide for the increase of efflux transporter activity to increase the efflux of calcineurin inhibitor from physiological compartments.

Priority: US20080076587P Applic. Date: 2008-06-27

Inventor: ROBBINS WENDYE [US]; LEE VING [US]


Application No.: US20090326531A1  Published: 31/Dec/2009

Title: MEDICAL INSTRUMENT

Applicant/Assignee:

Application No.: 12/444379   Filing Date: 26/Sep/2007

Abstract:

A medical tubular shaft instrument for gripping and cutting tissue which provides a safe mode of operation. The instrument includes electrodes by which a mechanical contact between a blade and an associated cutting surface can be electrically determined. This determination allows the operating physician to be provided with sufficient information to determine whether the tissue that is to be severed has been successfully severed.

Priority: DE200610046919 Applic. Date: 2006-10-05; DE200610046920 Applic. Date: 2006-10-05; DE200610047204 Applic. Date: 2006-10-05; DE200610047215 Applic. Date: 2006-10-05; DE200610059175 Applic. Date: 2006-12-14; WO2007EP08388 Applic. Date: 2007-09-26

Inventor: GEISELHART FRANZ [DE]


Application No.: US20090188945ND  Published: ND

Title: ND

Applicant/Assignee: ND

Application No.: ND   Filing Date: ND

Abstract:

ND

Priority: ND

Inventor: ND

US Patent Applications in Oral Care Formulation Granted in 2009
US Applications Published in 2010
 
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LIST OF US PATENT APPLICATIONS IN ORAL CARE FORMULATIONS PUBLISHED IN 2009
This list includes Provisional Patent Applications published in the United States. The list was retrieved by using a refined search strategy on the claims section of all patent applications.
Salient search terms included oral care formulations and compositions for tooth cleaning and whitening; denture and dental prosthesis care; caries, calculus, stains and plaque prevention,
reduction and removal of plaque; dental adhesives, dental polymers, cement curing; polymer UV curing, cavity fillers, disinfectants, bleaching; oral hygiene and devices, etc.
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