US Oral Care Formulation Patent Applications Published in 2008

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US PATENT APPLICATIONS IN ORAL CARE FORMULATION PUBLISHED IN 2008


Application No.: US20080000489A1  Published: 03/Jan/2008

Title: Method and preparation for binding aldehydes in saliva

Applicant/Assignee: BIOHIT OYJ

Application No.: 11/783333   Filing Date: 09/Apr/2007

Abstract:

The object of the invention is the use of compounds comprising one or more free sulphlydryl or amino groups for preparing a pharmaceutical composition for locally binding acetaldehyde in saliva, the stomach or the large intestine, and pharmaceutical compositions comprising the said compounds.

Priority: FI20000002392 Applic. Date: 2000-10-30; WO2005FI00429 Applic. Date: 2005-10-10; US2003-415422 Applic. Date: 2003-11-21; WO2001FI00948 Applic. Date: 2001-10-30; US20040617299P Applic. Date: 2004-10-08; US20050660723P Applic. Date: 2005-03-11

Inventor: SUOVANIEMI OSMO [FI]; SALASPURO MIKKO [FI]; SALASPURO VILLE [FI]; MARVOLA MARTTI [FI]


Application No.: US20080000614A1  Published: 03/Jan/2008

Title: HOT FLAVOR AND SKIN SENSATION COMPOSITION

Applicant/Assignee:

Application No.: 11/853656   Filing Date: 11/Sep/2007

Abstract:

The present invention relates to a flavor and skin sensation composition providing a hot or warming sensation upon consumption or application, respectively. The composition comprises a hot, warming component, a cooling component and a bitter component. In an embodiment, the composition further comprises an acid component. The composition provides a clean hot taste free of oily or earthy off-notes. Consumers prefer the composition over hot, warming compositions comprising essentially natural extracts.

Priority: EP20050102993 Applic. Date: 2005-04-15; WO2006IB51102 Applic. Date: 2006-04-11

Inventor: MAUREL CATHERINE D [CH]; LE ANH [US]; BARRA JEROME [FR]; STARKENMANN CHRISTIAN [CH]


Application No.: US20080001000A1  Published: 03/Jan/2008

Title: Device and method for forming water vapor

Applicant/Assignee:

Application No.: 11/707790   Filing Date: 15/Feb/2007

Abstract:

A device and method are provided for forming vapor mainly utilizing the atomization device to form low temperature water vapor, and then using an adjustable heating unit to warm the low temperature water vapor, or mixing some high temperature steam to get needed temperature water vapor. The invention uses the atomization device which mainly was used to humidify the air to form the needed water vapor in beauty, hairdressing, or health care so as to adjust the temperature of water vapor to solve the problems which are existing in the fields of beauty, hairdressing, health care, where the high temperature steam scalds a person more easily, and the temperature is difficult to control. The present invention makes the application of the steam in these fields more free, common and popular.

Priority: CN20061045326 Applic. Date: 2006-06-30

Inventor: YOU TUMING [CN]


Application No.: US20080002882A1  Published: 03/Jan/2008

Title: Brand protection and product autentication using portable devices

Applicant/Assignee:

Application No.: 11/477486   Filing Date: 30/Jun/2006

Abstract:

The present invention is a method and apparatus for protection of products and packaging against counterfeiting using dedicated authentication protocol coupled with portable devices. It is based on the product identification information, i.e., PIN, generated by the product manufacturer, stored in the product database and added to product or packaging in an open and/or a hidden form. The open part is directly available to the consumer before buying, opening or consuming the product or package or damaging its integrity while the hidden part is only revealed after these operations. The hidden information can also be disappearing after a predefined interval of time or number of trials or usages. Both parts are communicated to the authentication server in a predefined order to verify the product or package authenticity. The presence, absence, or multiple requests for the same product PIN, confirm or reject product authenticity or detect attempt at attacking the system or at using counterfeited products.

Priority:

Inventor: VOLOSHYNOVSKYY SVYATOSLAV [CH]; KOVAL OLEKSIY [CH]; PUN THIERRY [CH]


Application No.: US20080003187A1  Published: 03/Jan/2008

Title: High fluoride ion oral care composition and method for maintaining anticaries activity

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 11/479678   Filing Date: 30/Jun/2006

Abstract:

An oral care composition and method of maintaining anticaries activity of fluoride ion in an oral care composition are described. An oral care composition comprises a fluoride ion source sufficient to maintain a high fluoride content in the composition, an effective amount of a desensitizing agent and water. A method of maintaining anticaries activity of fluoride ion in an oral care composition comprises providing an oral care composition comprising fluoride ions, an effective amount of a desensitizing agent and water.

Priority:

Inventor: JOZIAK MARILOU T [US]; FISHER STEVEN W [US]


Application No.: US20080003202A1  Published: 03/Jan/2008

Title: Modified interferon-beta (IFN-beta) polypeptides

Applicant/Assignee:

Application No.: 11/729266   Filing Date: 27/Mar/2007

Abstract:

Provided are modified interferon-beta polypeptides and nucleic acid molecules encoding modified interferon-beta polypeptides and formulations containing the polypeptides and/or nucleic acid molecules. The modified polypeptides exhibit increased protein stability, including increased resistance to proteases. Also provided are methods of treatment by administering modified interferon-beta polypeptides.

Priority: US20060787208P Applic. Date: 2006-03-28

Inventor: GUYON THIERRY [FR]; BORRELLY GILLES [FR]; DRITTANTI LILA [FR]; VEGA MANUEL [FR]


Application No.: US20080003238A1  Published: 03/Jan/2008

Title: Products made with yellow mustard gum

Applicant/Assignee:

Application No.: 11/475952   Filing Date: 28/Jun/2006

Abstract:

Yellow mustard gum was used to produce varieties of new foods, cosmetics, paints, and industrial products including but not limited to the following products: nutraceutical beverages, nutraceutical sauces, nutraceutical salad dressings, nutraceutical confectionary products, cosmetics products, pharmaceutical products, paints products and chemical products and were claimed accordingly.

Priority:

Inventor: SHARAFABADI SOHEIL K [CA]


Application No.: US20080003267A1  Published: 03/Jan/2008

Title: Pharmaceutical Composition

Applicant/Assignee:

Application No.: 11/666086   Filing Date: 20/Oct/2005

Abstract:

The invention relates to pharmaceutical compositions suitable for oral administration in the form of edible films comprising diclofenac.

Priority: US20040620706P Applic. Date: 2004-10-21; WO2005US38090 Applic. Date: 2005-10-20

Inventor: SPENCER GAVIN M [FR]; SCHOBEL ALEXANDER M [US]; SLOMINSKI GREG [US]; MEYER STEPHAN [CH]; RAULT ISABELLE [FR]


Application No.: US20080003540A1  Published: 03/Jan/2008

Title: Electrochemically treating teeth

Applicant/Assignee: FLUORINEX ACTIVE LTD

Application No.: 11/476787   Filing Date: 29/Jun/2006

Abstract:

Electrochemical method for treating teeth: applying metal salt solution to teeth, applying ionizable substance to the teeth, and applying current flow to the teeth so as to ionize the ionizable substance. Electrochemical device for dental treatment: applicator for applying a substance to teeth, having a first end and a second end, a first electrode attached to first end of applicator, second electrode attached to second end of applicator, wherein first electrode and second electrode are configured for current flow through applicator, and an ionizable substance for placement within applicator, wherein ionizable substance is configured for ionization upon application of current flow through the substance.

Electrochemical teeth whitening method: applying metal salt solution to teeth, applying an oxidizing agent to teeth exposed to metal salt solution, and applying current flow to the teeth so as to activate and reduce the oxidizing agent for effecting whitening of the teeth.

Priority: WO2004IL01174 Applic. Date: 2004-12-29; US20030532570P Applic. Date: 2003-12-29

Inventor: KHAWALED KAMAL [IL]; JUBEH MAHER [IL]


Application No.: US20080004252A1  Published: 03/Jan/2008

Title: 3,8-Substituted 8-Aza-Bicyclo[3.2.1]Octane Derivatives and Their Use as Monomine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee: NEUROSEARCH A/S

Application No.: 11/794365   Filing Date: 11/Jan/2006

Abstract:

This invention relates to novel 8-aza-bicyclo[3.2.1]octane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000068 Applic. Date: 2005-01-13; US20050643590P Applic. Date: 2005-01-14; WO2006EP50143 Applic. Date: 2006-01-11

Inventor: PETERS DAN [DK]; DAHL BJARNE H [DK]; OLSEN GUNNAR M [DK]; NIELSEN ELSEBET O [DK]; SCHEEL-KRUGER JORGEN [DK]; REDROBE JOHN P [DK]


Application No.: US20080004271A1  Published: 03/Jan/2008

Title: Inhibitors of TNFalpha, PDE4 and B-RAF, compositions thereof and methods of use therewith

Applicant/Assignee:

Application No.: 11/654344   Filing Date: 16/Jan/2007

Abstract:

Provided herein are compounds having TNFalpha and/or PDE4 and/or B-RAF inhibitory activity, and compositions thereof. In particular, provided herein are compounds of the formula I: and pharmaceutically acceptable salts, solvates, hydrates, clathrates, stereoisomers, polymorphs and prodrugs thereof, wherein Ar, R<1>, R<2>, R<3>, R<4>, n and Z are as described herein. Further provided herein are methods for treating or preventing various diseases and disorders by administering to a patient one or more TNFalpha and/or PDE4 and/or B-RAF inhibitors. In particular, provided herein are methods for preventing or treating cancer, inflammatory disorders, cognition and memory disorders and autoimmune disorders, or one or more symptoms thereof by administering to a patient one or more TNFalpha and/or PDE4 and/or B-RAF inhibitors.

Priority: US20060759819P Applic. Date: 2006-01-17; US20060814862P Applic. Date: 2006-06-19; US20060818246P Applic. Date: 2006-06-30; US20060854637P Applic. Date: 2006-10-25

Inventor: MCKENNA JEFFREY M [GB]; PAPA PATRICK W [US]; SAKATA STEVEN T [US]; ERDMAN PAUL E [US]; PACKARD GARRICK K [US]


Application No.: US20080004353A1  Published: 03/Jan/2008

Title: New Anticonvulsant Compounds

Applicant/Assignee: HEJ RESEARCH INSTITUTE OF CHEMISTRY HEJ RESEARCH INSTITUTE KARACHI UNIVERSITY

Application No.: 11/307251   Filing Date: 01/Jul/2006

Abstract:

The invention relates to novel isoxylitones and their use as anticonvulsant and in the treatment of a variety of disorders

Priority:

Inventor: RAHMAN ATTAUR [PK]; CHOUDHARY MOHAMMAD IQBAL [PK]; SHAHEEN FARZANA [PK]; GANESAN A [GB]; SIMJEE SHABANA USMAN [PK]; RAZA A MOHSIN [PK]


Application No.: US20080004365A1  Published: 03/Jan/2008

Title: Dental Adhesive Composition

Applicant/Assignee: DENTSPLY DETREY GMBH

Application No.: 11/572613   Filing Date: 13/May/2005

Abstract:

One component dental adhesive composition having a pH of at most 3, comprising (a) a polymerisable acrylate monomer or prepolymer, (b) a photoinitiator, and (c) a solvent comprising t-butanol.

Priority: EP20040017749 Applic. Date: 2004-07-27; WO2005EP05263 Applic. Date: 2005-05-13

Inventor: BLACKWELL GORDON B [DE]


Application No.: US20080004369A1  Published: 03/Jan/2008

Title: Crosslinkable Biopolymer

Applicant/Assignee:

Application No.: 11/667929   Filing Date: 03/Nov/2005

Abstract:

The invention discloses composition, prepolymer and method to produce a polymer based on biodegradabler or essentially renewable crude materials, which can be crosslinked by free radicals. Composition is based on polyesters that are functionalised with unsaturated monomer units, in a way that unsaturated groups can be located along the polymer main chain as well as at the ends of the prepolymer. In connection to the product production, the prepolymer shall be exposed to free radicals that leads to network formation. The composition of the crosslinked biopolymer can be adjusted from a stiff engineering material to an elastic rubbery material. The new biopolymer can be used in composite materials, dispersions, barrier materials, rubbery materials, and in biomedical applications to mention a few possible application areas.

Priority: FI20040001476 Applic. Date: 2004-11-17; WO2005FI00471 Applic. Date: 2005-11-03

Inventor: SEPPALA JUKKA [FI]


Application No.: US20080004648A1  Published: 03/Jan/2008

Title: ORAL CARE IMPLEMENT

Applicant/Assignee:

Application No.: 11/852621   Filing Date: 10/Sep/2007

Abstract:

An oral care implement with a handle includes a head with a releasable material (e.g., an oral medicament) and a tissue cleanser for cleaning the soft tissues and removing odor-causing bacteria from the mouth. In one arrangement, the releasable material is disposed on the surface of the tissue cleanser. In one arrangement, the releasable material is disposed behind the tissue cleanser. In one arrangement, the releasable material is incorporated in the composition of the tissue cleanser.

Priority: US2004-986809 Applic. Date: 2004-11-15; US2004-869922 Applic. Date: 2004-06-18; US2003-601106 Applic. Date: 2003-06-20; US20040600701P Applic. Date: 2004-08-11

Inventor: HOHLBEIN DOUGLAS J [US]; WONG CHI SHING [US]


Application No.: US20080006289A1  Published: 10/Jan/2008

Title: Flossing Device With Internal Floss Feed

Applicant/Assignee:

Application No.: 11/858232   Filing Date: 20/Sep/2007

Abstract:

A flossing device having internal floss feed in which floss is advanced from a storage chamber inside the handle of the device, through feed gears, to a pair of spaced apart tines. Spent floss is returned through the return gears, the return drive gear having a greater diameter than the feed drive gear, thus ensuring the floss remains taut between the tines. An integral cutter allows the spent floss to be cut off and discarded. The cover over one or both sets of gears may be open at the top and bottom to allow cleaning of the gears. A flexible tile may be included over the aperture through which the floss exits the storage chamber to prevent water incursion therein. A floss advance lever advances the floss by a single action when pressed forward, which creates and maintains sufficient tensions on the floss resulting in taut and snug floss between the tines.

Optionally, the flossing head has a vibratory device to aid in the flossing action.

Priority: US2004-846575 Applic. Date: 2004-05-17

Inventor: FILSOUF EHSAN [US]


Application No.: US20080006660A1  Published: 10/Jan/2008

Title: Automatic swing-away knife sheath retaining strap

Applicant/Assignee: HEDGEHOG LEATHERWORKS LLC

Application No.: 11/481715   Filing Date: 06/Jul/2006

Abstract:

A knife sheath is provided. In various embodiments, the knife sheath includes an automatic swing-away retention strap that includes at least one biasing device. The biasing device is adapted to automatically pivot a detachable distal end of the retention strap about a fixed proximal end of the retention strap to swing the retention strap from a fastened position to an open position.

Priority:

Inventor: SCHEITER PAUL ALAN [US]


Application No.: US20080008660A1  Published: 10/Jan/2008

Title: Antimicrobially active compounds for treating bad breath

Applicant/Assignee: SYMRISE GMBH & CO. KG

Application No.: 11/812085   Filing Date: 14/Jun/2007

Abstract:

The invention relates primarily to specific uses of a compound of the Formula 1 or of mixtures of two or more different compounds of the Formula 1, in particular for producing an antimicrobially acting agent and agent against bad breath, as well as the corresponding production methods. In addition the invention relates to specific products, in particular oral hygiene products, comprising or consisting of a compound of the Formula 1 or of a mixture of two or more different compounds of the Formula 1 wherein the radicals of the compound of the Formula 1 or of each compound of the Formula 1 in the mixture are as defined in the preceding description.

Priority: WO2006EP63175 Applic. Date: 2006-06-14; US20060842999P Applic. Date: 2006-09-08

Inventor: RABENHORST JURGEN [DE]; MACHINEK ARNOLD [DE]; SCHMAUS GERHARD [DE]; HERRMANN MARTINA [DE]; VIELHABER GABRIELE [DE]; PILLAI RAVIKUMAR [US]


Application No.: US20080008666A1  Published: 10/Jan/2008

Title: Breath Test for Oral Malodor

Applicant/Assignee:

Application No.: 10/592552   Filing Date: 14/Mar/2005

Abstract:

Measured of airway in samples a mammal, such as a human being, having oral malodor are analyzed for the presence of markers for the oral malodor. The mammal may subsequently be treated for this condition, and measured samples of airway breath again taken to determine the effectiveness of the treatment.

Priority: US20040552566P Applic. Date: 2004-03-12; US20040562742P Applic. Date: 2004-04-16; WO2005US08553 Applic. Date: 2005-03-14

Inventor: PHILLIPS MICHAEL [US]


Application No.: US20080008668A1  Published: 10/Jan/2008

Title: PERSONAL CARE COMPOSITIONS WITH GLYCERIN AND HYDROXYPROPYL QUATERNARY AMMONIUM SALTS

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER

Application No.: 11/851405   Filing Date: 07/Sep/2007

Abstract:

A personal care composition is provided formulated with glycerin and a moisturization enhancing agent which is a salt of structure AB, wherein A is a cationic charged component, B is an anionic charged component, and A has at least one quaternized nitrogen atom and at least two hydroxyl groups and a molecular weight no higher than about 400.

Priority: US2005-222104 Applic. Date: 2005-09-08; US2004-972483 Applic. Date: 2004-10-25

Inventor: HARICHIAN BIJAN [US]; MCMANUS RICHARD L [US]; HURLEY MEGAN K [US]; MINER PHILIP E [US]; CHANDAR PREM [US]; BARROW STEPHEN R [US]


Application No.: US20080008675A1  Published: 10/Jan/2008

Title: Odor eliminating items and methods of use for hunting

Applicant/Assignee: JOHNSON LABORATORIES, INC

Application No.: 11/898873   Filing Date: 17/Sep/2007

Abstract:

A regimen for hunting includes using a number of zeolite-containing personal items in connection with a hunter's apparel and body to reduce the hunter's scent for improved hunting. The personal items include mouthwash, deodorant/anti-perspirant, body and boot powder, bar and liquid soap for cleansing the body and hair, laundry detergent and dryer sheets. Each of the personal items includes an effective amount of zeolite, so that use of the personal items reduces the available scent to be detected by animals in the wild. The regimen can also include the use of a seat cushion that is covered with an activated carbon-containing fabric for odor control and/or elimination.

Priority: US2005-082777 Applic. Date: 2005-03-18; US2002-141075 Applic. Date: 2002-05-09; US2000-574208 Applic. Date: 2000-05-19; US19990136760P Applic. Date: 1999-05-28

Inventor: JOHNSON LOUIS B [US]


Application No.: US20080008728A1  Published: 10/Jan/2008

Title: Dehydrated dentifrice and toothbrush

Applicant/Assignee:

Application No.: 11/818316   Filing Date: 14/Jun/2007

Abstract:

A toothbrush has one or two part-spherical pockets formed in the brush surface. Balls or pellets of matching shape of dehydrated toothpaste are placed in the depressions, the brush is wetted and the pellets turn to a gel, ready for brushing. The pellets may be of various colors and flavors to entice children to brush their teeth and may be dispensed from a storage chamber carried in the tooth brush handle.

Priority: US20060813383P Applic. Date: 2006-06-14

Inventor: ATKIN JOSHUA D [US]


Application No.: US20080008769A1  Published: 10/Jan/2008

Title: Treatment of urinary tract infections

Applicant/Assignee:

Application No.: 11/481210   Filing Date: 05/Jul/2006

Abstract:

The invention provides a method for treating urinary tract infections in a patient by providing a mouth rinsing composition which releases free molecular iodine into the mucous membranes which enters into the urinary tract.

Priority:

Inventor: SIEGEL GREGG [US]; SIEGEL PHYLLIS [US]


Application No.: US20080008980A1  Published: 10/Jan/2008

Title: Laser augmented periodontal scaling instruments

Applicant/Assignee: NOMIR MEDICAL TECHNOLOGIES, INC

Application No.: 11/825550   Filing Date: 06/Jul/2007

Abstract:

An instrument is provided to enables a dental professional to subject a surgical site simultaneously to (1) mechanical cutting, scraping and grinding, and (2) laser trimming and cauterization. As a result, simultaneous removal of diseased tissue and destruction of residual bacteria is enabled. The instrument comprises a hollow shank having, a rearward fitting, and a forward contact head. Within shank extends a fiber optic bundle. As shown, laser energy is delivered from a laser through the fitting and the laser bundle to the contact head. In the contact head are a surgical blade and an exit window for the laser energy.

Priority: US2003-723031 Applic. Date: 2003-11-26; US20020430294P Applic. Date: 2002-12-02

Inventor: BORNSTEIN ERIC [US]


Application No.: US20080009222A1  Published: 10/Jan/2008

Title: Game caller

Applicant/Assignee:

Application No.: 11/820778   Filing Date: 20/Jun/2007

Abstract:

A game caller wherein a reed assembly thereof may be replaced or interchanged and marketed in customized kits provided with elements for repairing or customizing the game caller, and a horn piece thereof is comprised of a pliable material that is pinched, or squeezed, or manipulated, or otherwise deformed by the hunter into a closed relation, at least in part, to change the volume of air through the horn piece and sound pipe whereby to imitate distress sounds during a hunting situation wherein game is coaxed and/or attracted.

Priority: US20060815002P Applic. Date: 2006-06-20

Inventor: LOMBARDI JAMES S [US]


Application No.: US20080009557A1  Published: 10/Jan/2008

Title: Light emitting diode curable acrylates with reduced yellowing

Applicant/Assignee: BISCO, INC

Application No.: 11/481544   Filing Date: 06/Jul/2006

Abstract:

Dental compositions and methods of curing the composition utilizing a light emitting diode (LED) curing unit. According to one aspect, a composition comprising a multiacrylate compound, an initiator including camphorquinone and at least one amine, and a colorless anti-yellowing agent produces a scratch free surface having no oxygen inhibited layer when cured with the LED curing unit.

Priority:

Inventor: FENG LI [US]; SUH BYOUNG I [US]


Application No.: US20080010774A1  Published: 17/Jan/2008

Title: METHOD AND DEVICE FOR CLEANING THE AIR INTAKE SYSTEM OF A DIESEL VEHICLE

Applicant/Assignee: BG PRODUCTS, INC

Application No.: 11/780151   Filing Date: 19/Jul/2007

Abstract:

A device and method for cleaning the air-intake system of an EGR-valve-equipped diesel engine includes a dispersion component which mixes air and a liquid cleaning solution before delivering them to the air intake system of a running diesel engine. A main air intake is blocked and the EGR valve is removed and replaced with a coupler that receives the dispersion component, whereby a pressure drop is created. The pressure drop creates sufficient vacuum so that cleaner may be administered into the air-intake duct of the running engine. The cleaning solution is provided to the dispersion component under pressure supplied by a pressurized air source.

Priority: US2003-722302 Applic. Date: 2003-11-25; US20030478582P Applic. Date: 2003-06-13

Inventor: ERWIN HAROLD E [US]; AUGUSTUS RICHARD [US]


Application No.: US20080011303A1  Published: 17/Jan/2008

Title: FLAT-FOLD RESPIRATOR WITH MONOCOMPONENT FILTRATION/STIFFENING MONOLAYER

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/693186   Filing Date: 29/Mar/2007

Abstract:

A flat-fold respirator is made from a stiff filtration panel joined to the remainder of the respirator through at least one line of demarcation. The panel contains a porous monocomponent monolayer nonwoven web that contains charged intermingled continuous monocomponent polymeric fibers of the same polymeric composition and that has sufficient basis weight or inter-fiber bonding so that the web exhibits a Gurley Stiffness greater than 200 mg and the respirator exhibits less than 20 mm H2O pressure drop. The respirator may be formed without requiring additional stiffening layers, bicomponent fibers, or other reinforcement and can be flat-folded for storage. Scrap from the manufacturing process may be recycled to make additional stiff filtration panel web.

Priority: US2006-457899 Applic. Date: 2006-07-17; US2006-457906 Applic. Date: 2006-07-17; US2006-461128 Applic. Date: 2006-07-31; US2006-461136 Applic. Date: 2006-07-31; US2006-461145 Applic. Date: 2006-07-31; US2006-461192 Applic. Date: 2006-07-31; US2006-461201 Applic. Date: 2006-07-31

Inventor: ANGADJIVAND SEYED A [US]; SPRINGETT JAMES E [US]; BRANDNER JOHN M [US]; JONES MARVIN E [US]; FOX ANDREW R [US]; BERRIGAN MICHAEL R [US]; STELTER JOHN D [US]


Application No.: US20080011481A1  Published: 17/Jan/2008

Title: Methods for Reverse-Circulation Cementing in Subterranean Formations

Applicant/Assignee: HALLIBURTON ENERGY SERVICES HALLIBURTON ENERGY SERVICES, INC

Application No.: 11/862270   Filing Date: 27/Sep/2007

Abstract:

Methods and systems for reverse-circulation cementing in subterranean formations are provided. An example of a method is a method of cementing casing in a subterranean well bore, comprising inserting a casing into the well bore, the casing comprising a casing shoe

equipping the casing with a well head, and a casing inner diameter pressure indicator

flowing an equilibrium fluid into the well bore

flowing a cement composition into the well bore after the equilibrium fluid

determining from the well-bore pressure indicator when the well bore pressure has reached a desired value

discontinuing the flow of cement composition into the well bore upon determining that the well bore pressure has reached a desired value

and permitting the cement composition to set in the subterranean formation. Examples of systems include systems for cementing casing in a well bore.

Priority: US2004-973322 Applic. Date: 2004-10-26

Inventor: BADALAMENTI ANTHONY M [US]; BLANCHARD KARL W [US]; CROWDER MICHAEL G [US]; FAUL RONALD R [US]; GRIFFITH JAMES E [US]; ROGERS HENRY E [US]; TURTON SIMON [US]


Application No.: US20080011482A1  Published: 17/Jan/2008

Title: Systems for Reverse-Circulation Cementing in Subterranean Formations

Applicant/Assignee: HALLIBURTON ENERGY SERVICES

Application No.: 11/862300   Filing Date: 27/Sep/2007

Abstract:

Methods and systems for reverse-circulation cementing in subterranean formations are provided. An example of a method is a method of cementing casing in a subterranean well bore, comprising inserting a casing into the well bore, the casing comprising a casing shoe

equipping the casing with a well head, and a casing inner diameter pressure indicator

flowing an equilibrium fluid into the well bore

flowing a cement composition into the well bore after the equilibrium fluid

determining from the well-bore pressure indicator when the well bore pressure has reached a desired value

discontinuing the flow of cement composition into the well bore upon determining that the well bore pressure has reached a desired value

and permitting the cement composition to set in the subterranean formation. Examples of systems include systems for cementing casing in a well bore.

Priority: US2004-973322 Applic. Date: 2004-10-26

Inventor: BADALAMENTI ANTHONY M [US]; BLANCHARD KARL W [US]; CROWDER MICHAEL G [US]; FAUL RONALD R [US]; GRIFFITH JAMES E [US]; ROGERS HENRY E [US]; TURTON SIMON [US]


Application No.: US20080012291A1  Published: 17/Jan/2008

Title: Cleaning or care apparatus for medical or dental instruments

Applicant/Assignee: W&H DENTALWERK BURMOOS GMBH W&H DENTALWERK BUERMOOS GMBH

Application No.: 11/581901   Filing Date: 16/Oct/2006

Abstract:

A connecting device of a cleaning or care apparatus or a cleaning cassette comprises a blocking device which is movable between a first position and a second position and prevents loosening or displacement of an instrument that is to be cleaned during a cleaning or care operation because of the pressure exerted by the cleaning or care media. In some embodiments, a direct or indirect operative connection between the blocking device and a component of the cleaning or care apparatus or between the blocking device and at least a part of the cassette is provided, which transmits to the blocking device the force required to move the blocking device from the first position into the second position.

In other embodiments, the blocking device is moved from the first position into the second position by the action of the media in the line, e.g., either by direct contact with the media or indirectly through contact with another intermediate element.

Priority: EP20050022643 Applic. Date: 2005-10-18

Inventor: HELFENBEIN GERALD [AT]; SCHAFFARZICK DANIEL [AT]


Application No.: US20080014224A1  Published: 17/Jan/2008

Title: Methods of Making Compositions Comprising Films

Applicant/Assignee:

Application No.: 11/457610   Filing Date: 14/Jul/2006

Abstract:

The invention relates to methods of making films having active ingredients. A film that is substantially free of active ingredient is introduced into a medium comprising an active ingredient. At least a portion of the active ingredient is transferred from the medium to the film. The films can be used in a variety of applications, including oral care, personal care, cleansing and/or home care compositions.

Priority:

Inventor: BOYD THOMAS J [US]; DILLON RENSL [US]; MILLER JEFFREY M [US]; VISCIO DAVID B [US]; GAFFAR ABDUL [US]


Application No.: US20080014560A1  Published: 17/Jan/2008

Title: DENTAL COMPOSITIONS AND METHODS WITH ARYLSULFINATE SALTS

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/778381   Filing Date: 16/Jul/2007

Abstract:

Polymerizable compositions and methods are provided that include an ethylenically unsaturated compound and an arylsulfinate salt. The polymerizable compositions are useful as hardenable dental compositions.

Priority: US2003-672814 Applic. Date: 2003-09-26

Inventor: FALSAFI AFSHIN [US]; KALGUTKAR RAJDEEP S [US]; OXMAN JOEL D [US]


Application No.: US20080015179A1  Published: 17/Jan/2008

Title: Modulators of muscarinic receptors

Applicant/Assignee:

Application No.: 11/644124   Filing Date: 22/Dec/2006

Abstract:

The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

Priority: US20050753187P Applic. Date: 2005-12-22

Inventor: MAKINGS LEWIS R [US]; BLANCO MIGUEL G [US]; HURLEY DENNIS J [US]; DRUTU IOANA [US]; RAFFAI GABRIEL [US]; BERGERON DANIELE M [US]; NAKATANI AKIKO [US]; TERMIN ANDREAS P [US]; SILINA ALINA [US]


Application No.: US20080015183A1  Published: 17/Jan/2008

Title: SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 11/864987   Filing Date: 29/Sep/2007

Abstract:

Substituted quinazolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US2006-345926 Applic. Date: 2006-02-01; US2003-347210 Applic. Date: 2003-01-21; US20020349920P Applic. Date: 2002-01-17; US20020350527P Applic. Date: 2002-01-22

Inventor: BAKTHAVATCHALAM RAJAGOPAL [US]; BLUM CHARLES A [US]; BRIELMANN HARRY [US]; CALDWELL TIMOTHY M [US]; DE LOMBAERT STEPHANE [US]; HODGETTS KEVIN J [US]; ZHENG XIAOZHANG [US]; KRAUSE JAMES E [US]; HERZBERG URI [US]; YOON TAEYOUNG [US]


Application No.: US20080015194A1  Published: 17/Jan/2008

Title: METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT

Applicant/Assignee:

Application No.: 11/626324   Filing Date: 23/Jan/2007

Abstract:

The present invention is directed to methods for developing one or more drugs for one or more targeted therapies and compositions derived therefrom. In accordance with one aspect of the present invention, combinatorial chemistry techniques for use with high throughput screening techniques for identifying small molecule affinity and/or activity interactions are avoided by instead utilizing the natural mechanisms of antigen response to effect a massively parallel screening of naturally occurring molecules against an antigen. Other aspects of the invention provide compositions derived therefrom as well as therapeutic methods of use for the compounds.

Priority: US20060761123P Applic. Date: 2006-01-23

Inventor: ERRICO JOSEPH P [US]; MUGRAGE BENJAMIN B [US]; TURCHI IGNATIUS J [US]


Application No.: US20080016603A1  Published: 24/Jan/2008

Title: ODOR ABSORBING SYSTEM AND METHOD

Applicant/Assignee: SUNBURST COMPANIES, INC

Application No.: 11/858617   Filing Date: 20/Sep/2007

Abstract:

An odor absorbing system includes a head covering article of clothing configured to be worn by a person. The head covering article of clothing includes a base layer comprising a cap section configured to substantially cover a head of the person wearing the article of clothing. An odor absorbing insert is removable attachable to the article of clothing.

Priority: US2007-881083 Applic. Date: 2007-07-25; US2004-024510 Applic. Date: 2004-12-29; US20040580303P Applic. Date: 2004-06-16

Inventor: NEWMAN ANTHONY E [US]


Application No.: US20080016663A1  Published: 24/Jan/2008

Title: Formed materials and strips used in fuel tanks and to prevent explosive reactions

Applicant/Assignee: PROTECHT SOLUTIONS SA

Application No.: 11/730919   Filing Date: 04/Apr/2007

Abstract:

The invention relates to a stamped or braided form of a solid material or foil that can be inserted into a tank or container, for example to prevent an explosion of fuel inside the tank. Various combinations of materials can be used to produce the forms and braids. In a preferred embodiment, two or more stamped, helical forms of a metal foil material are interlocked or linked together, and a wire or fiber is placed at least partially in the center of one of the helical forms. This structure presents advantageous properties when used in fuel tanks, and resists deformation. In addition, certain forms or structures can be designed and used so they can be easily removed from the container or tank.

Priority: WO2005CH00576 Applic. Date: 2005-10-04; US20040615026P Applic. Date: 2004-10-04

Inventor: KERBRAT RENAUD [CH]; JEBSEN JAN H [CH]


Application No.: US20080017205A1  Published: 24/Jan/2008

Title: Method and Device for Releasing Flavor and Odor Substances

Applicant/Assignee:

Application No.: 10/591648   Filing Date: 27/Jun/2007

Abstract:

A device for releasing substances into the mouth, that comprises an intra-oral pacifier provided with a sucking element that partially or fully occupies the mouth of a user. The sucking element is used for releasing flavor substances and is made from materials in the natural or unnatural latex family. An adequate amount of the substances is provided inside, or on the pacifier. The substances may include some nicotine for smoking cessation, antibacterial materials for curing intra-oral diseases, or flavor or odor substances.

Priority: IL20040160753 Applic. Date: 2004-03-04; WO2005IL00252 Applic. Date: 2005-03-03

Inventor: CHAZOT AHRON [IL]


Application No.: US20080019867A1  Published: 24/Jan/2008

Title: Urinalysis screening device

Applicant/Assignee:

Application No.: 11/582762   Filing Date: 19/Oct/2006

Abstract:

A urinalysis screening device is disclosed that comprises a container, a cap for the container which seals in the urine sample, and an assay assembly that fits into the container. The assay assembly contains a plurality of diagnostic strips that enables the urine to be analyzed for various substances

Priority: US20060832824P Applic. Date: 2006-07-22

Inventor: JOHNSON PAUL K [US]; COOPER CAROLYN J [US]; KOLAR SARAH [US]; MORPHEW ROBERT [US]; STRASSER RICHARD [US]


Application No.: US20080020343A1  Published: 24/Jan/2008

Title: DENTAL IMPLANT AND METHOD FOR MAKING AND INSTALLING SAME

Applicant/Assignee:

Application No.: 11/832213   Filing Date: 01/Aug/2007

Abstract:

A method for making a dental implant by obtaining images of the tooth pre-atraumatic tooth extraction and post extraction and using those images to computer generate and mill a titanium replacement implant employing CAD/CAM equipment. The implant includes a scalloped neck interface similar to the replaced tooth's scalloped cementoenamel junction, a polished neck area between a root portion and a crown portion, and the numeral for the tooth number imprinted on the implant's facial surface. Chevron retention fins are provided on the root portion for engaging the bone of the tooth socket or osteotomy when the implant is tapped into position. Retention grooves are provided on the crown portion to which a provisional crown is cemented slightly out of occlusion at the time the implant is placed. The provisional crown will be replaced with a permanent crown after osteointegration of the implant has occurred.

Priority: US2004-996118 Applic. Date: 2004-11-23

Inventor: MOUNT K T [US]


Application No.: US20080020351A1  Published: 24/Jan/2008

Title: Method and device for cleaning teeth

Applicant/Assignee:

Application No.: 11/888385   Filing Date: 01/Aug/2007

Abstract:

The invention is directed to a method and a device for cleaning teeth wherein a variety of cleaning tools are coupled to a common handle section for the individual cleaning of teeth. It relates in particular to a handle section of an electric dental cleaning device, with a coupling section for coupling various cleaning tools thereto, as well as said cleaning tools. According to the invention the handle section detects a coding provided on the respective cleaning tool attached. In dependence upon the respective coding detected, various functions of the dental cleaning device are controlled.

Priority: US2004-872016 Applic. Date: 2004-06-18; US2003-662237 Applic. Date: 2003-09-15

Inventor: HILSCHER ALEXANDER [DE]; MANNEBACH HORST [DE]; REICK HANSJORG [DE]; SCHWARZ-HARTMANN ARMIN [DE]; TRAWINSKI PETER [DE]; STRATMANN MARTIN [DE]; VORBECK WOLFGANG [DE]


Application No.: US20080021339A1  Published: 24/Jan/2008

Title: Anesthesia monitor, capacitance nanosensors and dynamic sensor sampling method

Applicant/Assignee:

Application No.: 11/588845   Filing Date: 26/Oct/2006

Abstract:

Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes such as anesthesia gases, CO2 and the like in human breath. An integrated monitor system and disposable sensor unit is described which permits a number of different anesthetic agents to be identified and monitored, as well as concurrent monitoring of other breath species, such as CO2. The sensor unit may be configured to be compact, light weight, and inexpensive. Wireless embodiments provide such enhancements as remote monitoring. A simulator system for modeling the contents and conditions of human inhalation and exhalation with a selected mixture of a treatment agent is also described, particularly suited to the testing of sensors to be used in airway sampling.

Priority: US2006-488456 Applic. Date: 2006-07-18; US20050730905P Applic. Date: 2005-10-27; US20060773138P Applic. Date: 2006-02-13; US20050748834P Applic. Date: 2005-12-09

Inventor: GABRIEL JEAN-CHRISTOPHE P [US]; JOSHI VIKRAM [US]; PASSMORE JOHN L [US]; SKARUPO SERGEI [US]; STAR ALEXANDER [US]; VALCKE CHRISTIAN [US]


Application No.: US20080021584A1  Published: 24/Jan/2008

Title: Methods and systems for management of information related to the appearance of an object

Applicant/Assignee:

Application No.: 11/902839   Filing Date: 26/Sep/2007

Abstract:

The present invention provides an improved system for measuring the appearance of an object, that improves upon the prior art systems by employing a digital CMOS camera and a variety of features attendant thereto, provides an improved calibration system, an improved quality control system, an improved tooth whitening system, and an improved crown design system.

Priority: CA20012343672 Applic. Date: 2001-04-11; CA20022372852 Applic. Date: 2002-02-19; US2003-682302 Applic. Date: 2003-10-10; WO2002IB02547 Applic. Date: 2002-04-11

Inventor: WHAITE PETER [CA]; TREMBLAY PIERRE-JULES [CA]


Application No.: US20080022503A1  Published: 31/Jan/2008

Title: Dental cleaning device

Applicant/Assignee:

Application No.: 11/888287   Filing Date: 31/Jul/2007

Abstract:

An electric toothbrush with a removable brush section having a transponder communicating with a handle portion of the toothbrush via a non-contacting inductive coupling.

Priority: DE20011059395 Applic. Date: 2001-12-04; US2004-872075 Applic. Date: 2004-06-18; US2002-241274 Applic. Date: 2002-09-10; US2004-872016 Applic. Date: 2004-06-18; US2003-662237 Applic. Date: 2003-09-15; WO2001EP02844 Applic. Date: 2001-03-14; US2004-871469 Applic. Date: 2004-06-18; US2001-811080 Applic. Date: 2001-03-16

Inventor: HILSCHER ALEXANDER [DE]; REICK HANSJORG [DE]; STRATMANN MARTIN [DE]; TRAWINSKI PETER [DE]; VORBECK WOLFGANG [DE]; SCHWARZ-HARTMANN ARMIN [DE]


Application No.: US20080023027A1  Published: 31/Jan/2008

Title: Dental Stick

Applicant/Assignee:

Application No.: 11/596502   Filing Date: 18/May/2004

Abstract:

The invention relates to medicine, in particular to dentistry. The inventive dental stick comprises a holder ( 1 ) provided with oppositely deflected massaging ( 2 ) and cleaning ( 3 ) elements tapered towards the ends thereof. Said holder is bent so that a fold is formed in the middle section thereof with two symmetrical segments ( 4 ) and ( 5 ) oppositely shifted with respect to a symmetry axis ( 6 ). Said symmetrical segments of the holder ( 1 ) have round cross sections ( 7 ) reducing away from the middle of the holder towards the massaging elements ( 2 ). Said massaging ( 2 ) and cleaning ( 3 ) elements are formed by two flat faces ( 8 ) and ( 9 ) which are perpendicular to the holder axis plane. The massaging elements are deflected to the sides which are opposite to the shift of the holder symmetrical segments with respect to the symmetry axis ( 6 ). The cleaning elements are provided with roundish-shaped extensions oppositely oriented with respect to the holder axis plane. The surfaces of the massaging elements which are opposite to the extension direction of the corresponding cleaning element are wave-shaped.

Priority: WO2004RU00189 Applic. Date: 2004-05-18

Inventor: IZMAYLOV VIKTOR I [RU]


Application No.: US20080024788A1  Published: 31/Jan/2008

Title: WAVELENGTH-TUNABLE LIGHT GENERATOR AND OPTICAL COHERENCE TOMOGRAPHY DEVICE

Applicant/Assignee: SCHOOL JURIDICAL PERSON KITASATO GAKUEN NIPPON TELEGRAPH AND TELEPHONE CORPORATION SCHOOL JURIDICAL PERSON KITASATO INSTITUTE

Application No.: 11/867736   Filing Date: 05/Oct/2007

Abstract:

The present invention provides an OCT technique that permits tomographic observation of a biological body parts that is difficult to restrain and also provides a tomographic observation technique for the observation of a constrainable part that does not require constraint and remove the burden from biological body. A wavelength-tunable light generator (wavelength-tunable light source) is employed as the light source of the optical coherence tomography device. The wavelength-tunable light generator has a wave number tunable range width of at least 4.7x10<-2 >mum<-1 >and an emitted-light frequency width of no more than 13 GHz, for example, and includes means capable of changing the wave number stepwise at wave number intervals of no more than 3.1x10<-4 >mum<-1 >and time intervals of no more than 530 mus.

Priority: JP20030335207 Applic. Date: 2003-09-26; JP20040202956 Applic. Date: 2004-07-09; JP20040202957 Applic. Date: 2004-07-09; US2004-573113 Applic. Date: 2004-09-22; WO2004JP14302 Applic. Date: 2004-09-22

Inventor: SHIMIZU KIMIYA [JP]; OHBAYASHI KOHJI [JP]; AMANO TAKUJI [JP]; HIRO-OKA HIDEAKI [JP]; CHOI DONGHAK [JP]; FURUKAWA HIROYUKI [JP]; NAKANISHI MOTOI [JP]; KANO FUMIYOSHI [JP]; MIYAZAWA TAKEO [JP]; YOSHIMURA RYOKO [JP]


Application No.: US20080025013A1  Published: 31/Jan/2008

Title: LED-POWERED DENTAL OPERATORY LIGHT

Applicant/Assignee: PELTON & CRANE

Application No.: 11/867876   Filing Date: 05/Oct/2007

Abstract:

A lamp assembly adapted to cast shadow-free illumination over an area. Typically, a lamp assembly includes a plurality of light modules that are disposed in a spaced apart relationship over an area. The lamp assembly can be arranged to focus light from the lamp to a central area of illumination of high intensity, with significantly reduced intensity illumination outside the central area.

Priority: US2005-120170 Applic. Date: 2005-05-02

Inventor: LOCKAMY H T [US]; UNSWORTH AUSTIN E [US]


Application No.: US20080025925A1  Published: 31/Jan/2008

Title: DENTAL BLEACHING COMPOSITIONS HAVING LONG-TERM RHEOLOGICAL STABILITY AND DEVICES, KITS AND METHODS THAT UTILIZE SUCH COMPOSITIONS

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/460016   Filing Date: 26/Jul/2006

Abstract:

Dental bleaching compositions include a dental bleaching agent, a generally linear high molecular weight (i.e., greater than about 500,000) polyvinyl pyrrolidone (PVP) and/or polyethylene oxide (PEO) tissue adhesion agent included in amount that imparts a high level of adhesiveness, a rheology-modifying agent such as fumed silica or fumed alumina that reduces or eliminates stringiness otherwise caused by the high molecular weight PVP and/or PEO, and a solvent or carrier. Dental bleaching compositions may include carboxypolymethylene instead of or in addition to PVP and/or PEO, wherein the fumed silica or fumed alumina increases long-term rheological stability even in the presence of a high concentration of dental bleaching agent. Dental treatment devices including a barrier layer and a quantity of the dental bleaching composition positioned adjacent to the barrier layer.

Priority:

Inventor: ALLRED PETER M [US]


Application No.: US20080025926A1  Published: 31/Jan/2008

Title: Oral care formulations with hydrogen peroxide and lycopene

Applicant/Assignee: DR. NICK'S WHITE & HEALTHY, LLC

Application No.: 11/491187   Filing Date: 24/Jul/2006

Abstract:

A toothpaste formulation is disclosed which comprises hydrogen peroxide

and cetylpyridinium chloride, and wherein the hydrogen peroxide and the cetylpyridinium chloride have been combined in the toothpaste formulation for not more than about seven minutes prior to administration to an individual. A mouth rinse formulation is disclosed which comprises hydrogen peroxide

and cetylpyridinium chloride, and wherein the hydrogen peroxide and the cetylpyridinium chloride have been combined in the mouth rinse formulation for not more than about seven minutes prior to administration to an individual. A whitening gel formulation is disclosed which comprises hydrogen peroxide

and pH adjuster, and wherein the hydrogen peroxide and the pH adjuster have been combined in the whitening gel formulation for not more than about seven minutes prior to administration to an individual. The toothpaste formulation, the mouth rinse formulation, and the whitening gel formulation further comprise lycopene.

Priority:

Inventor: KAVOUKLIS NICHOLAS M [US]; GAUDREAULT ROSEMARY A [US]


Application No.: US20080026058A1  Published: 31/Jan/2008

Title: METHODS FOR TREATING AND PREVENTING MUCOSITIS

Applicant/Assignee:

Application No.: 11/829138   Filing Date: 27/Jul/2007

Abstract:

Methods for treating and preventing mucositis, in particular mucositis following the administration of chemotherapy drugs or a combination of said drugs with radiotherapy, are disclosed herein. More specifically, disclosed herein is the administration of a therapeutically effective amount of at least one of an anthocyanoside, a proanthocyanidin, or an extract containing at least one of an anthocyanoside or a proanthocyanidin for the treatment or prevention of mucositis. The therapeutically effective amount of the anthocyanoside, proanthocyanidin or extract can be administered alone or in combination with a therapeutically effective amount of at least one of an anti-inflammatory agent, immunomodulating agent, analgesic, antimicrobial agent or antifungal agent. Also disclosed herein are pharmaceutical compositions for treating and preventing mucositis.

Priority: EP20060015732 Applic. Date: 2006-07-28

Inventor: BOMBARDELLI EZIO [IT]; MORAZZONI PAOLO [IT]


Application No.: US20080026341A1  Published: 31/Jan/2008

Title: Dental Model Tray And Associated Articulator

Applicant/Assignee:

Application No.: 10/589386   Filing Date: 26/Jan/2005

Abstract:

A dental model tray ( 12 ) for use in forming a dental model has a rigid bottom wall ( 16 ) and a relatively thin side wall ( 17 ) extending upwardly from the perimeter of the bottom wall ( 16 ) to form an open-topped cavity which is adapted to receive the dental casting material. The bottom wall ( 16 ) and the side wall ( 17 ) are formed integrally of polymeric material with the side wall ( 17 ) being joined to or attached to the bottom wall ( 16 ) by a thin membrane-like connector member ( 19 ) that is formed integrally with the perimeter bottom wall ( 16 ) and a lower side edge of the side wall ( 17 ). The connector member ( 19 ) is frangible and easily broken so that the side wall ( 17 ) can be torn away from the base and discarded after dental casting material has hardened in the cavity formed by the side wall ( 17 ).

Priority: US20040546406P Applic. Date: 2004-02-20; WO2005US03105 Applic. Date: 2005-01-26

Inventor: GARLAND JAMES K [US]


Application No.: US20080026400A1  Published: 31/Jan/2008

Title: Methods to identify biologically active agents and synergistic combinations

Applicant/Assignee: SYNERGY BIOSYSTEMS LTD

Application No.: 11/893401   Filing Date: 17/Aug/2007

Abstract:

Methods are described using a particular type of assay system, the Multi-Pathway High Throughput Assay, in conjunction with a novel experimental strategy, whereby repeated cycles of experiments result in the identification of the most effective synergistic combinations of potential active agents from a library of materials. The novel experimental strategy not only requires far fewer total experiments than would be required using conventional discovery strategies but also maximizes the probability of finding highly synergistic combinations through the principle of multiple-pathway intervention.

Priority: US2004-807811 Applic. Date: 2004-03-24; US20030457859P Applic. Date: 2003-03-26; US20030457860P Applic. Date: 2003-03-26; US20030457861P Applic. Date: 2003-03-26; US20030483564P Applic. Date: 2003-06-28

Inventor: SCOTT IAN R [GB]


Application No.: US20080027005A1  Published: 31/Jan/2008

Title: PEPTIDES EFFECTIVE IN THE TREATMENT OF TUMORS AND OTHER CONDITIONS REQUIRING THE REMOVAL OR DESTRUCTION OF CELLS

Applicant/Assignee:

Application No.: 11/756452   Filing Date: 31/May/2007

Abstract:

This application discloses compositions and methods for treating conditions requiring removal or destruction of harmful or unwanted cells in a patient, such as benign and malignant tumors, using compounds containing or based on multimeric peptides.

Priority: US20060820839P Applic. Date: 2006-07-31

Inventor: AVERBACK PAUL [CA]; GEMMELL JACK [CA]


Application No.: US20080027029A1  Published: 31/Jan/2008

Title: COLD MENTHOL RECEPTOR-1 ANTAGONISTS

Applicant/Assignee:

Application No.: 11/746318   Filing Date: 09/May/2007

Abstract:

The invention is directed to TRPM8 antagonists of Formula (I). More specifically, the present invention relates to certain novel compounds, methods for preparing compounds, compositions, intermediates and derivatives thereof and methods for treating TRPM8-mediated disorders. Pharmaceutical and veterinary compositions and methods of treating pain and various other disease states or conditions using compounds of the invention are also described.

Priority: US20060799275P Applic. Date: 2006-05-10; US20070915527P Applic. Date: 2007-05-02

Inventor: COLBURN RAYMOND W [US]; DAX SCOTT L [US]; FLORES CHRISTOPHER [US]; MATTHEWS JAY [US]; QIN NING [US]; REANY LAURA [US]; TELEHA CHRISTOPHER [US]; YOUNGMAN MARK A [US]


Application No.: US20080027067A1  Published: 31/Jan/2008

Title: Heterocyclic derivatives as modulators of ion channels

Applicant/Assignee: VERTEX PHARMACEUTICALS INCORPORATED

Application No.: 11/643622   Filing Date: 21/Dec/2006

Abstract:

The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Priority: US20050752926P Applic. Date: 2005-12-21; US20060791181P Applic. Date: 2006-04-11; US20060799797P Applic. Date: 2006-05-12; US20060839444P Applic. Date: 2006-08-23

Inventor: MARTINBOROUGH ESTHER [US]; FANNING LEV T [US]; SHETH URVI [US]; WILSON DEAN [US]; TERMIN ANDREAS [US]; NEUBERT TIMOTHY [US]; ZIMMERMANN NICOLE [US]; KNOLL TARA [US]; WHITNEY TARA [US]; KAWATKAR ARATI [US]; LEHSTEN DANIELLE [US]; STAMOS DEAN [US]; ZHOU JINGLAN [US]; ARUMUGAM VIJAYALAKSMI [US]; GUTIERREZ COREY [US]


Application No.: US20080027119A1  Published: 31/Jan/2008

Title: Methods and compositions employing bicifadine for the treatment of acute pain, chronic pain, and symptoms of neuropathic disorders

Applicant/Assignee:

Application No.: 11/260887   Filing Date: 26/Oct/2005

Abstract:

Methods and compositions are provided for formulating and administering bicifadine and related compounds to treat acute pain, chronic pain, and symptoms associated with neuropathic disorders.

Priority: US2003-621435 Applic. Date: 2003-07-17; US20020399852P Applic. Date: 2002-07-31

Inventor: LIPPA ARNOLD S [US]; STERN WARREN [US]; CODD JANET [IE]; BOLAND BRIAN [IE]; JOHNSON LIM [US]


Application No.: US20080027145A1  Published: 31/Jan/2008

Title: Therapeutic Molecules and Methods for Generating and/or Selecting Same

Applicant/Assignee:

Application No.: 10/588687   Filing Date: 03/Feb/2005

Abstract:

The present invention relates generally to therapeutic molecules useful for inducing apoptosis of particular cells such as, but not limited to, cancer cells and methods for generating and/or selecting same. The present invention further provides methods for inducing apoptosis of cells such as cancer cells and pharmaceutical compositions useful for same. The present invention further provides methods for generating or selecting therapeutic agents capable of inducing apoptosis of particular cells by the selective inhibition of pro-survival proteins. The present invention further provides a computational approach to therapeutic molecule design based on structure-binding characteristics.

Priority: AU20040900562 Applic. Date: 2004-02-06; WO2005AU00140 Applic. Date: 2005-02-03

Inventor: HUANG DAVID C S [AU]; COLMAN PETER M [AU]; DAY CATHERINE L [NZ]; ADAMS JERRY M [AU]; CHEN LIN [AU]; WILLIS SIMON N [AU]; WEI ANDREW [AU]; SMITH BRIAN J [AU]; HINDS MARK G [AU]


Application No.: US20080028549A1  Published: 07/Feb/2008

Title: Dental cleaning device

Applicant/Assignee:

Application No.: 11/888189   Filing Date: 31/Jul/2007

Abstract:

An electric toothbrush with a removable brush section having a transponder communicating with a handle portion of the toothbrush via a non-contacting inductive coupling.

Priority: DE20011059395 Applic. Date: 2001-12-04; US2004-872075 Applic. Date: 2004-06-18; US2002-241274 Applic. Date: 2002-09-10; US2004-872016 Applic. Date: 2004-06-18; US2003-662237 Applic. Date: 2003-09-15; WO2001EP02844 Applic. Date: 2001-03-14; US2004-871469 Applic. Date: 2004-06-18; US2001-811080 Applic. Date: 2001-03-16

Inventor: HILSCHER ALEXANDER [DE]; REICK HANSJORG [DE]; STRATMANN MARTIN [DE]; TRAWINSKI PETER [DE]; VORBECK WOLFGANG [DE]; SCHWARZ-HARTMANN ARMIN [DE]


Application No.: US20080028553A1  Published: 07/Feb/2008

Title: Training toothbrush with audio

Applicant/Assignee:

Application No.: 11/810624   Filing Date: 06/Jun/2007

Abstract:

A toothbrush device used for a unique teaching method for proper teeth brushing techniques by means of prerecorded audio commands emanating from the handle of the toothbrush. The toothbrush with audio is a product that is designed to easily and quickly provide a new and unique motivation for young children to brush their teeth correctly. This special toothbrush combined with an integral audio device to encourage and coach children on proper tooth brushing habits. The configuration comprises a handle that is slightly larger than a conventional toothbrush and the handle contains a waterproof speaker, a power switch, and a battery compartment. The extension neck and bristle are similar to conventional toothbrushes.

Priority: US20060812931P Applic. Date: 2006-06-13

Inventor: BATTHAUER JULIE A [US]


Application No.: US20080029086A1  Published: 07/Feb/2008

Title: Device and Method for Washing Nasal Passages

Applicant/Assignee: MED-SYSTEMS, INC

Application No.: 11/831794   Filing Date: 31/Jul/2007

Abstract:

A nasal passage washing device includes a pliable body including an open top

and an applicator cap removably attached to the pliable body to cover and uncover the open top. The applicator cap includes an applicator tip having a substantially frustoconical configuration sized and shaped for receipt at least partially within a nostril of a user for sealing engagement therewith, the applicator tip including a hole to transfer washing solution there through, a washing solution transfer tube in communication with the hole of the applicator tip and a bottom of an inside of the pliable body to transfer washing solution from the bottom of the inside of the pliable body to the hole of the applicator tip, and a one-way air valve that only allows air flow into the pliable body through the one-way air valve and does not allow air flow and washing solution flow out of the pliable body through the one-way air valve.

Priority: US20060821517P Applic. Date: 2006-08-04

Inventor: HARLAN JEFFREY [US]; HEATLEY DIANE [US]; GALLO DAVID [US]


Application No.: US20080029110A1  Published: 07/Feb/2008

Title: Smokeless Tobacco Composition

Applicant/Assignee: R. J. REYNOLDS TOBACCO COMPANY

Application No.: 11/781604   Filing Date: 23/Jul/2007

Abstract:

A smokeless tobacco product configured for insertion into the mouth of a user of the product is provided, the tobacco product including a water-permeable pouch containing a tobacco formulation, the tobacco formulation including a tobacco material and a plurality of microcapsules dispersed within the tobacco material, the plurality of microcapsules including an outer shell encapsulating an internal payload. The internal payload may include an additive such as water, flavorants, binders, colorants, pH adjusters, buffering agents, fillers, disintegration aids, humectants, antioxidants, oral care ingredients, preservatives, additives derived from herbal or botanical sources, and mixtures thereof.

Microencapsulated flavorants include tobacco-containing flavorants, such as tobacco extracts or a particulate tobacco material, sweeteners (e.g., sweeteners containing neotame), and vanillin (optionally in a complexed form).

Priority: US2006-351919 Applic. Date: 2006-02-10

Inventor: DUBE MICHAEL F [US]; CANTRELL DANIEL V [US]; MUA JOHN-PAUL [US]; HOLTON DARRELL E JR [US]; STOKES CYNTHIA S [US]; FIGLAR JAMES N [US]


Application No.: US20080029114A1  Published: 07/Feb/2008

Title: Multi-component filter providing multiple flavour enhancement

Applicant/Assignee: PHILIP MORRIS USA, INC PHILIP MORRIS USA INC

Application No.: 11/882115   Filing Date: 30/Jul/2007

Abstract:

A multi-component filter for a smoking article comprises: a mouth end segment

a first flavour release segment comprising plant leaf upstream of the mouth end segment

and a second flavour release segment comprising filtration material and a flavourant upstream of the first flavour release segment. The resistance to draw of the second flavour release segment is greater than the resistance to draw of the first flavour release segment and the resistance to draw of the second flavour release segment is greater than the resistance to draw of the mouth end segment. The multi-component filter preferably further comprises a rod end segment comprising filtration material upstream of the second flavour release segment, which has a lower resistance to draw than the second flavour release segment.

Priority: EP20060254102 Applic. Date: 2006-08-04

Inventor: SEITERT HUGUES [CH]; GAWAD AHMED [CH]; LEKILI LEVENT [CH]; KUERSTEINER CHARLES [CH]


Application No.: US20080029122A1  Published: 07/Feb/2008

Title: Power dental flosser

Applicant/Assignee:

Application No.: 11/474600   Filing Date: 26/Jun/2006

Abstract:

The present invention of the Power Dental Flosser uses a looped dental floss driven by a small electric motor to provide a continuous cleaning motion for a better teeth cleaning experience. At least one of the spool is capable of rotating with an attached tooth brush or with a tooth polishing what could be rotated in and out. The disposable dental loop is strong, made from naturally waxy polymer material preferably from a biodegradable thin-gauged high-density polyethylene (HDPE) or similar material.

Priority:

Inventor: EGERESI ZOLTAN [US]


Application No.: US20080031775A1  Published: 07/Feb/2008

Title: Device to alternately supply a fluid to an analyzer

Applicant/Assignee:

Application No.: 11/811913   Filing Date: 12/Jun/2007

Abstract:

Apparatus and methods for supplying a portion of a fluid stream and, alternately, a fluid of known composition and concentration to an analyzer are provided. The fluid stream is directed through a series of connected chambers formed in an integral housing. A sampling needle has an inlet in one of the chambers and an outlet in fluid communication with the analyzer. When desired, a tube or vial containing a known fluid may be inserted into a chamber containing the sampling needle, so that the known fluid will be supplied to the analyzer. A second needle provides ventilation to the vial to prevent the formation of a vacuum as the known fluid is drained from the vial.

Priority: US2003-352516 Applic. Date: 2003-01-28; US2001-894313 Applic. Date: 2001-06-27; US1999-368990 Applic. Date: 1999-08-05; US1998-191610 Applic. Date: 1998-11-13; US1996-629609 Applic. Date: 1996-04-09

Inventor: GODEC RICHARD D [US]; SILVESTER FRANK J [US]; BATEMAN BLAINE R [US]


Application No.: US20080031830A1  Published: 07/Feb/2008

Title: Dental Composition Containing an Epoxy Functional Carbosilane Compound

Applicant/Assignee: 3M ESPE AG

Application No.: 11/572062   Filing Date: 14/Jul/2004

Abstract:

The present invention relates to a dental composition comprising least one carbosilane compound comprising at least one Si-Aryl bond, at least one silicon atom, no Si-Oxygen bond, at least one aliphatic epoxy moiety, wherein said carbosilane compound has no glycidyl ether moieties

and an initiator, optionally filler and optionally additive components selected from the group of modifiers, stabilizers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavourings.

Priority: WO2004EP07791 Applic. Date: 2004-07-14

Inventor: ECKERT ADRIAN S [DE]; BISSINGER PETER [DE]; DEDE KARSTEN [DE]; KLETTKE THOMAS [DE]


Application No.: US20080031831A1  Published: 07/Feb/2008

Title: Oral anti-calculus compositions and methods of use thereof

Applicant/Assignee: TECHNOLOGY & MARKETING CONSULTING

Application No.: 11/255248   Filing Date: 21/Oct/2005

Abstract:

The present invention provides anticalculus oral compositions containing a plant oil mixture comprising a major oil constituent and a minor oil constituent in a proportion of at least 10/1 respectively. The major oil constituent comprises an edible vegetable oil and the minor oil consitutent comprises emulsifying oil, flavoring oil, antiseptic oil, anti-inflammatory oil, or a combination thereof.

Priority:

Inventor: LAALI MOEIN [DE]


Application No.: US20080031918A1  Published: 07/Feb/2008

Title: BARRIERS FOR POLYMERIC COATINGS

Applicant/Assignee: SURMODICS, INC

Application No.: 11/873747   Filing Date: 17/Oct/2007

Abstract:

A barrier adapted to be positioned between a first surface provided in the form of a polymeric, bioactive agent-containing coating upon a medical device, and a second surface provided by another material positioned in apposition, and preferably moveable apposition, to the first surface. The barrier, as provided by block copolymers or photoderivatized polymers, provides protection to the polymeric composition from mechanical damage and/or delamination during fabrication, storage, delivery or deployment, and/or residence of the device within the body. A combination that includes a medical device, such as a stent, and another device, such as a surrounding sheath or internal expandable balloon, between which is positioned a barrier of the type described.

Priority: US2002-313234 Applic. Date: 2002-12-06

Inventor: LAWIN LAURIE R [US]; BOUCHA-RAYLE MICHELLE C [US]; KLOKE TIMOTHY M [US]


Application No.: US20080032914A1  Published: 07/Feb/2008

Title: Beta-Substituted Tetrahdropyrana (On) S And Method For The Synthesis And The Use Thereof

Applicant/Assignee: V. MANE FILS

Application No.: 11/659501   Filing Date: 05/Aug/2005

Abstract:

The invention relates, in particular to a tetrahydropyran(on) compound which is substituted in position beta with respect to a cycle oxygen of formula (I), wherein a substituent R is a linear alkyl radical in C2:C10 including, (CH3)2CH- or C6H5-(CH2)m-, with m=0 or 1, or formula (II), wherein A is -CH2- or -CO-, in the form of an odorant and to a method for the synthesis thereof by reducing oxo-ester. The use of the inventive compound in composition such as perfumery compositions in the ordinary sense of the term i.e. topic, in particular cosmetic compositions and care products.

Priority: FR20040008729 Applic. Date: 2004-08-06; WO2005FR02038 Applic. Date: 2005-08-05

Inventor: MANE JEAN [FR]; CHANOT JEAN-JACQUES [FR]; SCHROEDER MARTIN [FR]


Application No.: US20080033002A1  Published: 07/Feb/2008

Title: Modulators of muscarinic receptors

Applicant/Assignee:

Application No.: 11/823762   Filing Date: 28/Jun/2007

Abstract:

The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

Priority: US20060817385P Applic. Date: 2006-06-29

Inventor: BANDARAGE UPUL K [US]; XU JINWANG [US]; DAVIES ROBERT J [US]; CHARIFSON PAUL S [US]; ARIMOTO RIEKO [US]


Application No.: US20080038046A1  Published: 14/Feb/2008

Title: Dental Cleaning Substance Medium, Packaging, and Device

Applicant/Assignee:

Application No.: 11/836134   Filing Date: 08/Aug/2007

Abstract:

A single-use portion of dental cleaning substance provided in a tidy, convenient, and hygienic manner. The single-use portion of dental cleaning substance may be provided in a solid form and may be utilized via a traditional toothbrush (electronic or standard) or by use of a specific device.

Priority: US20060822095P Applic. Date: 2006-08-11; US20070911585P Applic. Date: 2007-04-13

Inventor: JALILI REZA [US]


Application No.: US20080038224A1  Published: 14/Feb/2008

Title: Modified interferon-beta (IFN-beta) polypeptides

Applicant/Assignee:

Application No.: 11/729267   Filing Date: 27/Mar/2007

Abstract:

Provided are modified interferon-beta polypeptides and nucleic acid molecules encoding modified interferon-beta polypeptides and formulations containing the polypeptides and/or nucleic acid molecules. The modified polypeptides exhibit increased protein stability, including increased resistance to proteases. Also provided are methods of treatment by administering modified interferon-beta polypeptides.

Priority: US20060787208P Applic. Date: 2006-03-28

Inventor: GUYON THIERRY [FR]; BORRELLY GILLES [FR]; DRITTANTI LILA [FR]; VEGA MANUEL [FR]


Application No.: US20080038338A1  Published: 14/Feb/2008

Title: Tetracycline Package Formulations

Applicant/Assignee:

Application No.: 11/763860   Filing Date: 15/Jun/2007

Abstract:

The invention provides a rapidly disintegrating and dissolving multilayer tablet comprising at least a tetracycline in a first layer, a buffer in a second layer, and optionally, an inert layer separating the first and second layers. The multilayer tablets of the invention are useful for treating or preventing mucositis, when administered topically to the oral cavity.

Priority: US20060813949P Applic. Date: 2006-06-15

Inventor: SMITH ALEXANDER D [US]; COBB JOE [US]; BETTIS JOHN [US]; STAGNER WILLIAM C [US]; GOLD BRAD [US]


Application No.: US20080038554A1  Published: 14/Feb/2008

Title: Media

Applicant/Assignee: BRIGHTWATER ENGINEERING LIMITED

Application No.: 11/662049   Filing Date: 08/Sep/2005

Abstract:

Plastic particles of a selected one of various shapes are usage in a floating media bed of a biological aerated flooded filter. They may be manufactured by injection moulding or by an extrusion-and-chopping method comprising advancing molten plastics through a channel-form extrusion die slot 30, cooling the extruded plastics in water, and chopping-off transversely by a die head face cutter 34 pieces of the cooled channel-form plastics, the distribution of the volumetric rate of flow of the plastics over the outlet mouth of the die slot 30 being such that the external surface of the base of the cooled channel-form plastics is longitudinally convex.

Priority: GB20040019901 Applic. Date: 2004-09-08; WO2005GB03460 Applic. Date: 2005-09-08

Inventor: CANTWELL ALAN D C [GB]


Application No.: US20080038686A1  Published: 14/Feb/2008

Title: Methods and kits for early stage caries detection

Applicant/Assignee:

Application No.: 11/787158   Filing Date: 13/Apr/2007

Abstract:

Methods and kits are provided for identifying very early stage carious lesions using a detectable probe that binds to the lesion.

Priority: US20060792768P Applic. Date: 2006-04-18; US20060819135P Applic. Date: 2006-07-07; US20070901421P Applic. Date: 2007-02-15; US20060850922P Applic. Date: 2006-10-11

Inventor: NAGAI SHIGEMI [US]


Application No.: US20080038690A1  Published: 14/Feb/2008

Title: Dental finishing, sanding and/or polishing floss

Applicant/Assignee:

Application No.: 11/891820   Filing Date: 13/Aug/2007

Abstract:

An abrading dental floss is characterized by dental floss having a dental abrasive on at least a portion thereof suitable for polishing, sanding and/or finishing dental restorative material such as dental resin. The dental abrading material is impregnated into or provided onto the dental floss. In one form, the dental abrading floss has an abrading/abrasion/polishing/finishing/sanding section situated between lengths of the dental floss. The abrading polishing section may be formed of an alternating pattern of non-abrasive portions and abrasive portions along a length of the floss. The abrasive portions may be of a single grit or texture of the dental abrasive or may be of different grits of the dental abrasive. In another form, the dental abrading floss has a single grit of a dental abrasive along its entire length. In yet another form, the dental abrading floss comprises a plastic sheet of having a dental abrasive thereon or therein situated between lengths of the dental floss. The dental abrasive may be of a single grit or different grits of the dental abrasive. For different grits of the dental abrasive, it is preferred, but not necessary, that they gradually change in grit size.

Priority: US20060837482P Applic. Date: 2006-08-14

Inventor: ALLEN JEFFREY T [US]


Application No.: US20080039459A1  Published: 14/Feb/2008

Title: Phosphoinositide 3-kinase inhibitor compounds and methods of use

Applicant/Assignee: PLRAMED LIMITED GENENTECH, INC PIRAMED LIMITED

Application No.: 11/789427   Filing Date: 24/Apr/2007

Abstract:

Compounds of Formulas Ia and Ib, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula Ia and Ib for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Priority: US20060795047P Applic. Date: 2006-04-26

Inventor: FOLKES ADRIAN [GB]; SHUTTLEWORTH STEPHEN [GB]; OXENFORD SALLY [GB]; HANCOX TIM [GB]; BAYLISS TRACY [GB]; CASTANEDO GEORGETTE [US]; GOLDSMITH RICHARD [US]; GUNZNER JANET [US]; HEFFRON TIM [US]; MALESKY KIMBERLY [US]; MATHIEU SIMON [US]; OLIVERO ALAN [US]; SUTHERLIN DANIEL P [US]; TSUI VICKIE [US]; WANG SHUMEI [US]; WIESMANN CHRISTIAN [US]; ZHU BING-YAN [US]; DOTSON JENNAFER [US]


Application No.: US20080039478A1  Published: 14/Feb/2008

Title: Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof

Applicant/Assignee: RENOVIS, INC

Application No.: 11/773106   Filing Date: 03/Jul/2007

Abstract:

Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

Priority: US2006-384045 Applic. Date: 2006-03-17; US20050664903P Applic. Date: 2005-03-24; US20050709186P Applic. Date: 2005-08-18; US20050710077P Applic. Date: 2005-08-22; US20050712778P Applic. Date: 2005-08-31; US20050721390P Applic. Date: 2005-09-28; US20050753194P Applic. Date: 2005-12-22

Inventor: KELLY MICHAEL G [US]; KINCAID JOHN [US]


Application No.: US20080039592A1  Published: 14/Feb/2008

Title: Dental Polymerizable Composition

Applicant/Assignee: KURARAY MEDICAL INC

Application No.: 11/659811   Filing Date: 11/Aug/2005

Abstract:

A dental polymerizable composition comprising (a) a fluorine compound comprising a chain polymer having a main chain comprising a monomer unit having a hydrophilic group, and terminal groups comprising a fluoroalkyl group at each of both ends of the main chain

(b) a polymerizable monomer

and (c) a polymerization initiator. The dental polymerizable composition can be suitably used, for example, for dental composite resins, such as dental composite filler materials, crowning materials, and bonding materials

dental adhesive agents, such as teeth-straightening adhesive agents, cavity-coating adhesive agents, and tooth fissure sealing materials

denture base materials, denture base mucosal adjusting materials, fissure sealants, coating agents applied to tooth surface or dental prosthetic, surface glazes, and the like, and especially for various coating applications, for example, a fissure sealant, a coating agent to tooth surface or dental prosthetic, surface stains or a surface glaze, a hypersensitive inhibitor, a dental manicure, or the like.

Priority: JP20040234622 Applic. Date: 2004-08-11; WO2005JP14744 Applic. Date: 2005-08-11

Inventor: SAWADA HIDEO [JP]; TAGAMI JUNJI [JP]; NIKAIDO TORU [JP]; MATIN KHAIRUL [JP]; KADOMA YOSHINORI [JP]; MASUHARA EIICHI [JP]; OKADA KOICHI [JP]; YAMAUCHI JUNICHI [JP]


Application No.: US20080039906A1  Published: 14/Feb/2008

Title: Light therapeutic device

Applicant/Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Application No.: 11/905943   Filing Date: 05/Oct/2007

Abstract:

A light therapeutic device for an affected part is provided. The light therapeutic device includes an optical element providing light with at least one specific wavelength for treatment of the affected part. When the optical element contacts the affected part, the optical element has a shape corresponding to the shape of the affected part.

Priority: TW20040141350 Applic. Date: 2004-12-30; US2005-074724 Applic. Date: 2005-03-09

Inventor: HUANG SHENG B [TW]; CHEN CHIU L [TW]; YIN SUN B [TW]; YU YU C [TW]


Application No.: US20080041490A1  Published: 21/Feb/2008

Title: Nozzle For Filling A Container With At Least Two Viscous Materials

Applicant/Assignee:

Application No.: 11/791314   Filing Date: 22/Nov/2005

Abstract:

Nozzle ( 1 ) for filling a container with at least a first and a second viscous or paste-like material, of the type including an outer cylindrical body ( 6 ) having a delivery mouth ( 7 ). The nozzle has at least two cylindrical chambers ( 8, 9 ), placed inside said outer cylindrical body and fluidly separated, for the respective passage of the first and of the second viscous material, each of said at least two chambers having an outflow section ( 10, 11 ) of the relative viscous material substantially positioned in correspondence to said delivery mouth.

Priority: IT2004MI02284 Applic. Date: 2004-11-25; WO2005IB03502 Applic. Date: 2005-11-22

Inventor: TOGNI GIANCARLO [IT]


Application No.: US20080041590A1  Published: 21/Feb/2008

Title: Methods for Reverse-Circulation Cementing in Subterranean Formations

Applicant/Assignee: HALLIBURTON ENERGY SERVICES HALLIBURTON ENERGY SERVICES INC

Application No.: 11/862292   Filing Date: 27/Sep/2007

Abstract:

Methods and systems for reverse-circulation cementing in subterranean formations are provided. An example of a method is a method of cementing casing in a subterranean well bore, comprising inserting a casing into the well bore, the casing comprising a casing shoe

equipping the casing with a well head, and a casing inner diameter pressure indicator

flowing an equilibrium fluid into the well bore

flowing a cement composition into the well bore after the equilibrium fluid

determining from the well-bore pressure indicator when the well bore pressure has reached a desired value

discontinuing the flow of cement composition into the well bore upon determining that the well bore pressure has reached a desired value

and permitting the cement composition to set in the subterranean formation. Examples of systems include systems for cementing casing in a well bore.

Priority: US2004-973322 Applic. Date: 2004-10-26

Inventor: BADALAMENTI ANTHONY M [US]; BLANCHARD KARL W [US]; CROWDER MICHAEL G [US]; FAUL RONALD R [US]; GRIFFITH JAMES E [US]; ROGERS HENRY E [US]; TURTON SIMON [US]


Application No.: US20080041809A1  Published: 21/Feb/2008

Title: Closure device for drinking vessel

Applicant/Assignee:

Application No.: 11/496479   Filing Date: 01/Aug/2006

Abstract:

A closure device for use at the opening of a drinking vessel, comprises a body for connection to the drinking vessel at the opening, and a valve comprising a valve member supported by the body for movement relative to the body, between an inner open position allowing flow of liquid from inside to outside of the drinking vessel through the opening and an outer closed position sealing the opening. A spring resiliently biases the valve member towards the closed position. The valve member has an internal passage through which liquid from inside the drinking vessel may flow out of the drinking vessel when the valve member is in the open position.

Priority:

Inventor: SHEK TAT KIT [HK]


Application No.: US20080041867A1  Published: 21/Feb/2008

Title: Drink Cup and Lid

Applicant/Assignee: BERRY PLASTICS CORPORATION

Application No.: 11/876831   Filing Date: 23/Oct/2007

Abstract:

A liquid container includes a brim forming an opening into a liquid reservoir chamber formed in the cup. A lid is coupled to the brim to form more than one seal with the container. The lid includes lid-removal blocker walls arranged to engage undercuts formed in the cup to retain the lid in a mounted position on the cup closing the opening into the liquid reservoir chamber.

Priority: US2005-210085 Applic. Date: 2005-08-23; US2004-824753 Applic. Date: 2004-04-15

Inventor: JOCHEM DAVID J [US]; MARAVICH MILAN C [US]; MANN JEFFREY A [US]


Application No.: US20080044111A1  Published: 21/Feb/2008

Title: TRASH BAG HAVING FLEXIBLE SOLID EDGE

Applicant/Assignee:

Application No.: 11/735240   Filing Date: 13/Apr/2007

Abstract:

A bag for collecting refuse or yard waste is disclosed. The bag may include one or more solid edges to keep the bag open when in a horizontal or when in an upright position. The solid edge may flip out to act as a guide for refuse into the bag. The bag may also include a loop handle that may be held by the user to facilitate the bag staying open in the horizontal position, or a hook or clip that facilitates the bag staying open in the upright position.

Priority: US20060791415P Applic. Date: 2006-04-13

Inventor: FARAONE ROSEMARIE [US]


Application No.: US20080044351A1  Published: 21/Feb/2008

Title: METHOD AND PROCEDURE TO DETECT ORAL TISSUES WITH HIGH-RISK MOLECULAR PROFILES

Applicant/Assignee:

Application No.: 11/464536   Filing Date: 15/Aug/2006

Abstract:

A diagnostic method for detecting high risk oral tissue which due to chromosome allelic loss and may have developed or will potentially develop into carcinoma in situ and carcinoma by using a staining agent. A set of questionnaire that identifies high-risk individual and high-risk lesions and helps to reduce false positive for the diagnosis of oral tissue with high-risk molecular profile. A recording sheet with oral cavity diagram that helps to record the examination results more accurately and reduce the examination errors. This improved method has a broad application that can be used to screen the oral tissues with high risk molecular profile from hyperplasia, dysplasia, erythroplasia, leukoplasia, leukoerythroplasia, erythroleukoplasia, verrucous lesion, ulcerative lesion, carcinoma in situ, and carcinoma.

Priority:

Inventor: YE XIN [US]


Application No.: US20080044363A1  Published: 21/Feb/2008

Title: Therapeutic Dental Composition

Applicant/Assignee: BRITESMILE PROFESSIONAL, LLC

Application No.: 11/927129   Filing Date: 29/Oct/2007

Abstract:

A solid or semi-solid oral therapeutic dental composition comprising a therapeutic agent dispersed in a water-insoluble or water-resistant carrier. The dental composition may be in the form of a crayon or dispensed from a delivery device such as a pen or the like.

Priority: US2004-846207 Applic. Date: 2004-05-14; US20030471427P Applic. Date: 2003-05-16

Inventor: MONTGOMERY R E [US]


Application No.: US20080044444A1  Published: 21/Feb/2008

Title: Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof

Applicant/Assignee: FOAMIX LTD

Application No.: 11/825406   Filing Date: 05/Jul/2007

Abstract:

The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester

a stabilizer selected from the group consisting of at least one surface-active agent

at least one polymeric agent and mixtures thereof

a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.

Priority: IL20020152486 Applic. Date: 2002-10-25; US2005-532618 Applic. Date: 2005-12-22; WO2003IB05527 Applic. Date: 2003-10-24; US2005-078902 Applic. Date: 2005-03-11; US2007-717897 Applic. Date: 2007-03-13; US2007-653205 Applic. Date: 2007-01-12; US2004-835505 Applic. Date: 2004-04-28; US2004-911367 Applic. Date: 2004-08-04; US20060818634P Applic. Date: 2006-07-05; US20020429546P Applic. Date: 2002-11-29; US20030492385P Applic. Date: 2003-08-04; US20030530015P Applic. Date: 2003-12-16

Inventor: TAMARKIN DOV [IL]; FRIEDMAN DORON [IL]; BERMAN TAL [IL]; ZIV ENBAL [IL]; SCHUZ DAVID [IL]


Application No.: US20080044451A1  Published: 21/Feb/2008

Title: Biological Surfaces

Applicant/Assignee: RHO-BEST COATING HARTSTOFFBESCHICHTUNGS GMBH

Application No.: 11/792613   Filing Date: 07/Dec/2005

Abstract:

A base body contains a substrate that is at least partially coated with a carbon-containing layer. The carbon-containing layer is at least partially functionalized with a molecule that is bound directly or via at least one linker or functional group to the carbon-containing layer. The base body, which has a functionalized carbon-containing surface, is capable of influencing biological processes during a corresponding functionalization.

Priority: AT20040002063 Applic. Date: 2004-12-07; WO2005AT00495 Applic. Date: 2005-12-07

Inventor: STEINMULLER-NETHL DORIS [AT]; STEINMULLER DETLEF [AT]; KLOSS FRANK R [AT]; GASSNER ROBERT [AT]; BONN GUNTHER [AT]; HUCK CHRISTIAN W [AT]; NAJAM-UL-HAQ MUHAMMED [AT]; RAINER MATTHIAS [AT]; STECHER GUNTHER [AT]


Application No.: US20080044488A1  Published: 21/Feb/2008

Title: Nano Glass Powder and Use Thereof, in Particular Multicomponent Glass Powder with a Mean Particle Size of Less Than 1 [mu]m

Applicant/Assignee: SCHOTT AG

Application No.: 11/597959   Filing Date: 25/May/2005

Abstract:

A glass powder or a glass-ceramic powder is provided that includes multicomponent glasses with at least three elements, where the glass powder or a glass-ceramic powder has a mean particle size of less than 1 mum. In some embodiments, the mean particle size is less than 0.1 mum, while in other embodiments the mean particle size is less than 10 nm.

Priority: DE200410026433 Applic. Date: 2004-05-29; WO2005EP05633 Applic. Date: 2005-05-25

Inventor: ZIMMER JOSE [DE]; DAIMER JOHANN [DE]; RINDT MATTHIAS [DE]; KESSLER SUSANNE [DE]; BESINGER JOERN [DE]; SENESCHAL-MERZ KARINE [DE]


Application No.: US20080044788A1  Published: 21/Feb/2008

Title: DOUBLE ENDED LIGHTED DENTAL CLEANER

Applicant/Assignee:

Application No.: 11/465593   Filing Date: 18/Aug/2006

Abstract:

A lighted dental cleaning and inspection device. The device includes a handle having an end including a dental tool and an illumination source positioned and operable to direct light toward a tip portion of the dental tool

and an electrical circuit located substantially within the handle and being operable to selectively enable illumination of the illumination source to illuminate the tip portion of the dental tool and an area of interest during use of the dental tool at the site of interest.

Priority:

Inventor: JANSHESKI JOHN M [US]; SHANKLE LEX [US]


Application No.: US20080045454A1  Published: 21/Feb/2008

Title: Polynucleotide encoding a TRIM-cyp polypeptide, compositions thereof, and methods of using same

Applicant/Assignee:

Application No.: 11/650384   Filing Date: 05/Jan/2007

Abstract:

The invention provides an isolated nucleic acid encoding a TRIM-cyclophilin A fusion sequence encoding a TRIMcyp fusion protein which is active as an anti-viral agent, and in particular an anti-HIV-1 agent. The invention provides for a nucleic acid encoding a polypeptide having both TRIM activity and cyclophilin activity. The invention provides for an isolated polynucleotide encoding a TRIM-cyclophilin fusion protein, or variants thereof retaining the TRIM and cyclophilin activities. The invention provides for compositions thereof, antibodies that specifically bind thereto, and vectors and host cells comprising the nucleic acid or polypeptide. In addition, the invention provides for methods for treating or preventing viral infection, or reducing viral load in a subject comprising administering the nucleic acid, polypeptide, vector, or composition to the subject in an amount effective to treat or prevent the viral infection. In some embodiments, the viral infection is HIV-1 infection, hepatitis C infection, pox virus infection, vaccinia virus infection, or HTLV infection.

Priority: WO2005US23803 Applic. Date: 2005-07-06; US20040585925P Applic. Date: 2004-07-06

Inventor: LUBAN JEREMY [US]; SAYAH DAVID [US]


Application No.: US20080045525A1  Published: 21/Feb/2008

Title: Piperazinyl-Pyridine Analogues

Applicant/Assignee:

Application No.: 11/793129   Filing Date: 13/Dec/2005

Abstract:

Piperazinyl-pyridine analogues are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to. modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20040635822P Applic. Date: 2004-12-13; WO2005US45184 Applic. Date: 2005-12-13

Inventor: BAKTHAVATCHALAM RAJAGOPAL [US]; BLUM CHARLES A [US]; CHENARD BERTRAND L [US]; ZHENG XIAOZHANG [US]


Application No.: US20080045536A1  Published: 21/Feb/2008

Title: FUSED HETEROCYCLIC COMPOUNDS USEFUL AS KINASE MODULATORS

Applicant/Assignee: BRISTOL-MYERS SQUIBB COMPANY

Application No.: 11/689132   Filing Date: 21/Mar/2007

Abstract:

Compounds having the formula (I), and enantiomers, and diastereomers, pharmaceutically-acceptable salts, thereof, are useful as kinase modulators, including MK2 modulation, wherein one of E and F is a nitrogen atom and the other of E and F is a carbon atom, Z is N or CR3, and R1, R2, R3, X and Y are as defined herein.

Priority: US2006-524996 Applic. Date: 2006-09-21; US20050719519P Applic. Date: 2005-09-22

Inventor: VACCARO WAYNE [US]; CHEN ZHONG [US]; DODD DHARMPAL S [US]; HUYNH TRAM N [US]; LIN JAMES [US]; LIU CHUNJIAN [US]; MUSSARI CHRISTOPHER P [US]; TOKARSKI JOHN S [US]; TORTOLANI DAVID R [US]; WROBLESKI STEPHEN T [US]; LIN SHUQUN [US]


Application No.: US20080045575A1  Published: 21/Feb/2008

Title: Delivery of H2 Antagonists

Applicant/Assignee:

Application No.: 11/793884   Filing Date: 20/Dec/2005

Abstract:

The present invention provides methods for treating or preventing periodontal disease in a mammal subject. The inventive methods comprise topically administering to the subject an effective amount of a H2 antagonist encapsulated in liposomes. Preferably, the H2 antagonist, for example, Cimetidine, is encapsulated into paucilamellar liposomes, such as Novasome(R) microvesicles. The inventive methods may be used to treat and/or prevent gingivitis, periodontitis, aphthous ulcers, or herpetic stomatitis. Alternatively, the inventive methods may be used to treat and/or prevent a systemic disease associated with periodontal disease, such as cardiovascular diseases, pregnancy complications, and diabetes.

Priority: US20040639892P Applic. Date: 2004-12-29; WO2005US46280 Applic. Date: 2005-12-20

Inventor: VAN DYKE THOMAS E [US]; HOLICK MICHAEL [US]; KANTARCI ALPDOGAN [US]; HASTURK HATICE [US]


Application No.: US20080045591A1  Published: 21/Feb/2008

Title: Chemical Compounds

Applicant/Assignee: PHYTOPHARM PLC

Application No.: 11/773952   Filing Date: 05/Jul/2007

Abstract:

Compounds of general formula I: wherein: R1 and R2 are, independently of each other, selected from hydrogen, optionally substituted C1-10alkyl, optionally substituted -CO-(C1-10alkyl), optionally substituted C3-10cycloalkyl, optionally substituted -CO-(C3-10cycloalkyl), optionally substituted C2-10alkenyl, optionally substituted -CO-(C2-10alkenyl), optionally substituted aryl, and optionally substituted -CO-aryl, or R1 and R2 together represent an optionally substituted saturated or unsaturated C1-10alkylidene group, or an optionally substituted saturated or unsaturated C3-10cycloalkylidene group, or R1 and R2 together with the carbon atom to which they are attached represent an optionally substituted saturated or unsaturated organic ring containing 3, 4, 5, 6, 7 or 8 ring carbon atoms and optionally 1, 2 or 3 ring heteroatoms selected from O, N and S

R3, which may be the same as, or different from, either of R1 and R2, is selected from optionally substituted C1-10alkyl, optionally substituted C3-10cycloalkyl, optionally substituted C2-10alkenyl, and optionally substituted aryl

R4, R5 and R6 are, independently of each other, selected from hydrogen, optionally substituted C1-10alkyl, OH, optionally substituted C1-10 alkoxy, halo, optionally substituted aryloxy, optionally substituted (C1-10alkyl)-S(O)n- where n=0, 1 or 2, optionally substituted aryl-S(O)n- where n=0, 1 or 2, or R4 is hydrogen and R5 and R6 together represent an optionally substituted saturated or unsaturated organic chain containing 1, 2, 3, 4, 5, 6 or 7 chain carbon atoms and optionally 1, 2 or 3 chain heteroatoms selected from O, N and S, provided that the chain is at least 3 atoms long

with the proviso that, when R1-R2=hydrogen, then any optionally substituted C1-10alkyl or optionally substituted C2-10alkenyl for R3 must have a branch point at one or more of the alpha and beta positions counted from the carbonyl group (or tautomeric form thereof) to which R3 is attached

or a physiologically acceptable salt, complex or prodrug thereof

are disclosed per se and for use in the treatment or prophylaxis of hypersensitivity, smooth muscle disorders, spasmodic conditions, allergic conditions, inflammatory conditions and/or pain.

Priority: GB20060013518 Applic. Date: 2006-07-06

Inventor: REES DARYL D [GB]; GUNNING PHILLIP J [GB]; ORSI ANTONIA [GB]; HOWSON PATRICK A [GB]; BARRACLOUGH PAUL [GB]; CALLIZOT NOELLE [GB]


Application No.: US20080045626A1  Published: 21/Feb/2008

Title: Dental Compositions Containing Carbosilane Polymers

Applicant/Assignee:

Application No.: 11/571949   Filing Date: 13/Jul/2005

Abstract:

Carbosilane-containing polymers (including oligomers) having the following structural features: greater than one repeat unit

at least 4 Si-arylene bonds

at least 1 (meth)acrylate moiety, Si-H moiety, or both

no Si-O bonds

preferably at least 4 silicon atoms

wherein 2 silicon atoms are separated by one arylene group in each repeat unit.

Priority: US20040587978P Applic. Date: 2004-07-14; WO2005US24821 Applic. Date: 2005-07-13

Inventor: LEWANDOWSKI KEVIN M [US]; ABUELYAMAN AHMED S [US]; JONES TODD D [US]; GADDAM BABU N [US]; MITRA SUMITA B [US]; KARIM NAIMUL [US]; ECKERT ANDRIAN S [DE]; BISSINGER PETER [DE]


Application No.: US20080045628A1  Published: 21/Feb/2008

Title: Production of Acrylate-Based Solid

Applicant/Assignee:

Application No.: 11/664152   Filing Date: 03/Nov/2005

Abstract:

According to the invention, there is a method for producing an acrylate-based solid, comprising the steps of: (i) dispersing less than 20% w/v of an alkyl or aryl acrylate polymer/copolymer in a solvent comprising at least one acrylic monomer

(ii) dispersing in the fluid mixture formed by step (i) a further quantity of an alkyl or aryl acrylate polymer/copolymer

and (iii) curing the resulting material to form a solid, Wherein the alkyl or aryl acrylate polymer/copolymer of step (i) contains less than 0.1% w/w of a free radical.

Priority: GB20040024353 Applic. Date: 2004-11-03; GB20040027576 Applic. Date: 2004-12-16; WO2005GB04262 Applic. Date: 2005-11-03

Inventor: AHIR VALLABHBHAI B [GB]


Application No.: US20080047092A1  Published: 28/Feb/2008

Title: COVERAGE ROBOTS AND ASSOCIATED CLEANING BINS

Applicant/Assignee: IROBOT CORPORATION

Application No.: 11/751267   Filing Date: 21/May/2007

Abstract:

An autonomous coverage robot includes a chassis, a drive system configured to maneuver the robot, and a cleaning assembly. The cleaning assembly includes a cleaning assembly housing and at least one driven sweeper brush. The robot includes a controller and a removable sweeper bin configured to receive debris agitated by the driven sweeper brush. The sweeper bin includes an emitter disposed on an interior surface of the bin and a receiver disposed remotely from the emitter on the interior surface of the bin and configured to receive an emitter signal. The emitter and the receiver are disposed such that a threshold level of accumulation of debris in the sweeper bin blocks the receiver from receiving emitter emissions. The robot includes a bin controller disposed in the sweeper bin and monitoring a detector signal and initiating a bin full routine upon determining a bin debris accumulation level requiring service.

Priority: US20060747791P Applic. Date: 2006-05-19; US20060803504P Applic. Date: 2006-05-30; US20060807442P Applic. Date: 2006-07-14

Inventor: SCHNITTMAN MARK [US]; OZICK DANIEL N [US]; LANDRY GREGG W [US]


Application No.: US20080047862A1  Published: 28/Feb/2008

Title: Tote bag for organizing, securing and safely transporting laundry supplies

Applicant/Assignee:

Application No.: 11/508483   Filing Date: 23/Aug/2006

Abstract:

A tote bag for organizing, securing and safely transporting laundry supplies which comprises a box-shaped housing having a bottom wall, a pair of side walls, a rear wall and a lower front wall. A flap can be folded over to cover a top and an upper front portion area of the box-shaped housing. A plurality of box-shaped laundry supply containers are sized and proportioned so that they can fit within the box-shaped housing in a side-by-side relationship to utilize almost the entire confines of the box-shaped housing without any appreciable left over wasted space therein. A mechanism is for securing all of the box-shaped laundry supply containers snugly within the box-shaped housing. When the flap is opened and the securing mechanism is removed therefrom all of the box-shaped laundry supply containers can be easily taken out of the box-shaped housing.

Priority:

Inventor: CAPORRINO ROMINA V [US]


Application No.: US20080047865A1  Published: 28/Feb/2008

Title: WINE GLASS

Applicant/Assignee: BY THE GLASS, LLC

Application No.: 11/932179   Filing Date: 31/Oct/2007

Abstract:

A wine glass constructed from molded plastic includes an upper body defining an upwardly narrowed flume for concentrating the wine bouquet, in combination with a contoured lower base defining an annular moat surrounding a central punt for enhanced visual inspection of the wine. In addition, the upper body further includes a notched indent at an outboard side thereof forming a shelf for facilitated fingertip grasping and manipulation of the assembled glass. In one form, the upper body and lower base of the wine glass are provided as separate modules adapted for assembly to form the wine glass, and disassembly for respective compact stacking. In another form, the wine glass has a one-piece construction adapted for compact stacking by nested reception of the upwardly narrowed flume partially into the underside of the lower base of an overlying glass in the stack.

Priority: US2004-979847 Applic. Date: 2004-11-01; US2006-309159 Applic. Date: 2006-07-03; US2007-668046 Applic. Date: 2007-01-29

Inventor: WILLAT BOYD I [US]; PERRULLI JOSEPH T [US]; WILLAT AMBER R [US]; VELICK PAUL H [US]; DELGADO GARY D [US]


Application No.: US20080050318A1  Published: 28/Feb/2008

Title: Use of a combination of components with an inhibitory synergistic effect on calcium channels to prevent or treat wrinkles and fine lines

Applicant/Assignee: L'OREAL S.A

Application No.: 11/434266   Filing Date: 16/May/2006

Abstract:

Disclosed herein is a composition for topical application to skin, comprising, in a physiologically acceptable medium (i) at least one peptide comprising at least one amino acid sequence derived from the amino acid sequence of the protein SNAP 25, and (ii) at least one calcium-channel inhibitor. Further disclosed is the use of this combination in a composition suitable for topical application to the skin, as an agent for preventing or treating wrinkles and fine lines, such as expression wrinkles, as well as a cosmetic treatment process comprising applying to the skin the composition.

Priority: FR20020014183 Applic. Date: 2002-11-13; US2003-705857 Applic. Date: 2003-11-13; US20020427575P Applic. Date: 2002-11-20

Inventor: RENAULT BEATRICE [FR]


Application No.: US20080050398A1  Published: 28/Feb/2008

Title: Composition Comprising Beta-Defensin 2

Applicant/Assignee:

Application No.: 11/864386   Filing Date: 28/Sep/2007

Abstract:

The invention relates to compositions comprising at least one peptide with a structure or structural pattern of beta-defensin 2 and/or its derivatives, especially human beta-defensin 2. The compositions are selected in particular from cosmetic and/or pharmaceutical compositions, cleaning and/or washing agents, water-treatment agents and cooling lubricants. The invention also relates to the use of peptides with a structure or structural pattern of beta-defensin 2 and/or its derivatives, especially human beta-defensin 2, as an antimicrobial active ingredient in the aforementioned agents.

Priority: DE200510014687 Applic. Date: 2005-03-29; WO2006EP02760 Applic. Date: 2006-03-25

Inventor: BOCKMUEHL DIRK [DE]; HOEHNE HEIDE-MARIE [DE]


Application No.: US20080050407A1  Published: 28/Feb/2008

Title: ORAL CARE PRODUCTS COMPRISING BUFFER SYSTEMS FOR IMPROVED MINERALIZATION/REMINERALIZATION BENEFITS

Applicant/Assignee:

Application No.: 11/670737   Filing Date: 02/Feb/2007

Abstract:

Oral products for the improved mineralization/remineralization of teeth are provided. In an embodiment, the present disclosure provides an oral product comprising a calcium salt, a phosphate salt, a sodium salt and a potassium salt. For example, the molar ratio of the sodium salt to the potassium salt ranges from about 3 to about 4.

Priority: US20060765289P Applic. Date: 2006-02-03

Inventor: HAAS MICHAEL S [US]


Application No.: US20080050467A1  Published: 28/Feb/2008

Title: Cheese Products

Applicant/Assignee: DANISCO A/S

Application No.: 10/588320   Filing Date: 03/Feb/2005

Abstract:

The present invention relates to a composition and a method of preparing cheese products with a suitable moisture level. The cheese products that have been formed using the composition are characterised with an improve at least one of aroma, flavour, mildness, consistency, texture, syneresis, body, mouth feel, firmness, viscosity, gel fracture, wheying off, structure and/or organoleptic properties, nutrition and/or health benefits. In particular, the present invention provides a composition comprising a starter acidification micro-organism and an EPS fermentation culture comprising a viable micro-organism an enzyme produced by said micro-organism and an exopolysaccharide (EPS) produced by the activity of said enzyme.

Priority: GB20040002474 Applic. Date: 2004-02-04; GB20040003169 Applic. Date: 2004-02-12; US20040544331P Applic. Date: 2004-02-17; WO2005IB00427 Applic. Date: 2005-02-03

Inventor: SCHLOTHAUER RALF-CHRISTIAN [NZ]; RADEMACHER INEZ [DE]; PETERSEN HANS-UWE [DE]; HINRICHS JORG [DE]; LILLEVANG SOREN KRISTIAN [DK]


Application No.: US20080050693A1  Published: 28/Feb/2008

Title: NON-CUSTOM DENTAL TREATMENT TRAYS AND MOUTH GUARDS HAVING IMPROVED ANATOMICAL FEATURES

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/836664   Filing Date: 09/Aug/2007

Abstract:

A non-custom, dental tray device includes a moisture-resistant barrier layer having a labial-buccal wall, a lingual wall, and a bottom wall. The dental tray device includes at least one of the following structural features to enhance the fit of the device

(1) the bottom wall includes an abrupt reduction of width at a location corresponding to where the first bicuspid meets the canine

(2) a bottom wall in the posterior region having a width that is equal to or less than the width of the bottom wall in the anterior region, with no lingual wall in the posterior region

or (3) a transition portion between the bottom wall and either the labial-buccal wall or the lingual wall has a larger radius of curvature as compared to a radius of curvature at a transition portion between the bottom wall the other of the labial-buccal wall and the lingual wall.

Priority: US20060932982P Applic. Date: 2006-08-25

Inventor: FISCHER DAN E [US]; ALLRED PETER M [US]; JESSOP NEIL T [US]; MCLEAN BRUCE S [US]


Application No.: US20080050695A1  Published: 28/Feb/2008

Title: Fountain toothbrush

Applicant/Assignee:

Application No.: 11/821353   Filing Date: 22/Jun/2007

Abstract:

A toothbrush body includes a handle connected to a head and bristles projecting from the top of the head. A channel runs longitudinally through the body between a first opening and a second opening such that the first opening is in communication with the second opening through the channel. The channel and the first and second openings are arranged so that a substantially downward running stream of water directed into one of the first opening and the second opening is redirected through the channel and out of the other of the first opening and the second opening to form a fountain. A direction of a flow of the fountain at the other of the first opening and the second opening has an upward component so that a user, i.e., holder of the toothbrush, can easily reach the fountain for oral rinsing.

Priority: US2006-401702 Applic. Date: 2006-04-11

Inventor: AMRON SCOTT L [US]


Application No.: US20080050718A1  Published: 28/Feb/2008

Title: Methods, Articles, and Compositions for Identifying Oligonucleotides

Applicant/Assignee:

Application No.: 10/583198   Filing Date: 15/Nov/2004

Abstract:

There are many situations where oligonucleotides that efficiently bind a target DNA or RNA are desired. These oligonucleotides can be used for a variety of purposes, including antisense, diagnostics, and array generation. While researchers have worked for many years to identify algorithms and methods for predicting the oligonucleotides that will bind the target with the highest efficiency, better prediction methods are needed. Disclosed are methods, articles, machines, and compositions that aid in identifying oligonucleotides and sets of oligonucleotides that will efficiently bind a target nucleic acid molecule. Also disclosed are optimized sets of oligonucleotides that bind HIV-1 genomic RNA or DNA, such as the GAG RNA, and methods of using them.

Priority: US20030519911P Applic. Date: 2003-11-14; WO2004US38092 Applic. Date: 2004-11-15

Inventor: GESTELAND RAYMOND F [US]; ATKINS JOHN F [US]; MATVEEVA OLGA V [US]; SHABALINA SVETLANA A [US]


Application No.: US20080051330A1  Published: 28/Feb/2008

Title: Inhibitors of serine protease activity, methods and compositions for treatment of herpes viruses

Applicant/Assignee:

Application No.: 11/404041   Filing Date: 14/Apr/2006

Abstract:

Novel compositions and methods of treating and preventing a viral infection are provided. A method of blocking a viral infection facilitated by a serine proteolytic (SP) activity is disclosed, which involves administering to a subject suffering or about to suffer from a viral infection a therapeutically effective amount of a substance having serine protease inhibitory activity or serpin activity. Among the substances found to be useful are alpha1-antitrypsin (AAT), peptide derivatives from the carboxy terminal end of AAT and synthetic drugs mimicking the action of such substances. The invention is particularly well suited for checking a viral infection mediated by members of herpesviridae family.

Priority: US2000-518076 Applic. Date: 2000-03-03; US19990123167P Applic. Date: 1999-03-05; US19990153942P Applic. Date: 1999-09-15

Inventor: SHAPIRO LELAND [US]


Application No.: US20080051488A1  Published: 28/Feb/2008

Title: Dental Composition Containing Unsaturated Halogenated Aryl Alkyl Ether Components

Applicant/Assignee: TDK CORPORATION

Application No.: 11/572067   Filing Date: 14/Jul/2004

Abstract:

The invention relates to a dental composition comprising a) halogenated aryl alkyl ether component (A) comprising at least 1 aryl alkyl ether moiety, at least 1 halogen atom attached to each aryl residue of the aryl alkyl ether moieties, at least 2 unsaturated moieties, b) Si-H functional component (B), c) initiator (C), d) optionally filler (D), and e) optionally component (E) selected from modifiers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickness, surfactants, odorous substances, diluting agent(s) and flavourings.

Priority: WO2004EP07747 Applic. Date: 2004-07-14

Inventor: ECKERT ADRIAN S [DE]


Application No.: US20080051823A1  Published: 28/Feb/2008

Title: Devices and methods for treatment of obesity

Applicant/Assignee:

Application No.: 11/881144   Filing Date: 24/Jul/2007

Abstract:

Devices, methods for treatment of obesity, as well as instruments and tools used in placing, adjusting and maintaining devices for treatment of obesity. Various embodiments of devices that are implanted extra-gastrically are provided. Various embodiments of devices that are implanted intra-gastrically are provided. Methods include laparoscopic, percutaneous and/or trans-oral methods. Alternatively, devices describe can generally also be implanted by open surgical procedures.

Priority: US2007-716986 Applic. Date: 2007-03-10; US2007-716985 Applic. Date: 2007-03-10; US2006-407701 Applic. Date: 2006-04-19; US20060833284P Applic. Date: 2006-07-24; US20060877595P Applic. Date: 2006-12-28

Inventor: MAKOWER JOSHUA [US]; KIM STEVEN [US]; SHIU BRIAN K [US]; UEMURA SHUJI [US]; ACOSTA PABLO G [US]


Application No.: US20080051850A1  Published: 28/Feb/2008

Title: METHOD AND DEVICES FOR STIMULATION OF AN ORGAN WITH THE USE OF A TRANSECTIONALLY PLACED GUIDE WIRE

Applicant/Assignee: INTRAPACE, INC

Application No.: 11/830419   Filing Date: 30/Jul/2007

Abstract:

Devices, systems and methods are provided for electrical stimulation of a body organ, particularly within the gastrointestinal tract. In preferred embodiments, the stomach is the organ within the gastrointestinal tract which is targeted for such stimulation. A guide wire or other delivery device is positioned within the body so as to transect the stomach wall. Devices and systems are then advanced over the guide wire for attachment to the stomach wall. The guide wire may be placed by endoscopic, open, laparoscopic or a modified percutaneous approach. In a modified percutaneous approach, the stomach is accessed without the use of general anesthesia by advancing a needle through the abdomen, transecting the stomach wall with the needle and advancing the guide wire through the needle.

In some embodiments, particularly for use in obese patients, the modified percutaneous approach includes advancing a trocar through the tissue of the patient toward the outer surface of the organ and advancing the needle through the trocar prior to transecting the wall with the needle.

Priority: US20060821370P Applic. Date: 2006-08-03

Inventor: SPARKS KURT D [US]; BRYNELSEN CHARLES R [US]; IMRAN MIR A [US]


Application No.: US20080051860A1  Published: 28/Feb/2008

Title: Cosmetic mask and method of using

Applicant/Assignee:

Application No.: 11/894901   Filing Date: 22/Aug/2007

Abstract:

A multi-layer cosmetic mask designed to enhance the absorption of skin care compositions is disclosed. The mask comprises a thermally reflective layer, composed of foil or similar material, and a thermally insulating layer, composed of fleece or similar material. A method of using the cosmetic mask is also disclosed, comprising the steps of applying a moisturizing composition to the skin, applying the thermally reflective foil layer over the moisturizer, and then applying the thermally insulating mask layer over the foil layer. The combination of layers increases the temperature under the mask, and thereby increases the absorption of the moisturizing composition into the skin of a user.

Priority: ZA20060007007 Applic. Date: 2006-08-22

Inventor: WYK JOHAN D V [ZA]


Application No.: US20080052848A1  Published: 06/Mar/2008

Title: Oral Care Implement

Applicant/Assignee:

Application No.: 11/932010   Filing Date: 31/Oct/2007

Abstract:

An oral care implement with a handle includes a head with a tissue cleanser. The tissue cleanser may be a pad composed of an elastomeric material. The pad is disposed on the head on a surface opposite the tooth cleaning elements. The tissue cleanser may include a plurality of nubs extending for cleaning between the papillae of the tongue. The tissue cleanser may include a plurality of conically shaped nubs. A tissue cleanser can be used to reduce oral malodor problems and remove oral epithelial cells.

Priority: US2006-566479 Applic. Date: 2006-12-04; US2004-869922 Applic. Date: 2004-06-18; US2003-601106 Applic. Date: 2003-06-20; US20020414117P Applic. Date: 2002-09-27; US20020418776P Applic. Date: 2002-10-16; US20020419425P Applic. Date: 2002-10-18; US20020412290P Applic. Date: 2002-09-20

Inventor: HOHLBEIN DOUGLAS J [US]


Application No.: US20080053459A1  Published: 06/Mar/2008

Title: Anti-Snoring Device

Applicant/Assignee:

Application No.: 11/470319   Filing Date: 06/Sep/2006

Abstract:

An inter-lip device for regulating mouth airflow to prevent snoring while sleeping. A canoe shaped horizontal pocket is formed by hinge-ably attaching two resilient panels together by three common edges, sized to fit between the lips without protruding into the mouth. An adhesive covering is applied to both outer faces of the pocket and a slit is cut in the middle of the front edge hinge. The pocket opens to the rear into the mouth. The lips are sealed to the adhesive about the pocket opening, holding the mouth closed while directing mouth breathing through the device and out the front slit opening. With the jaw consciously flexed, resting mouth airflow is comfortably allowed, however, a relaxed sleeper's jaw or a forced inhalation will collapse the slit opening, reducing or stopping airflow, causing the user to breath through their nose, thereby preventing the necessary mouth airflow needed to support snoring.

Priority:

Inventor: SILKER NEIL BRADLEY [US]


Application No.: US20080053480A1  Published: 06/Mar/2008

Title: Burr hog cleaning device

Applicant/Assignee:

Application No.: 11/897750   Filing Date: 01/Sep/2007

Abstract:

An automated cleaning device for dental drill bits, also called dental burrs. The cleaning device includes an enclosed cleaning compartment that houses two rotating, circular brushes. The dental burr is guided through a small opening in the cleaning compartment and forced in between the two rotating brushes. The dental burr is rotated while between the brushes and moved in and out of the brushes during the cleaning process. A switch attached to the opening in the cleaning compartment allows the brushes to start rotating when a dental burr is inserted into the compartment, and stop when the burr is removed. The device includes an electric motor that can be powered by batteries or by plugging into a traditional electrical outlet.

Priority: US20060841375P Applic. Date: 2006-09-01

Inventor: HANCOCK J DENNIS [US]; KIMMEL SHAWN [US]


Application No.: US20080054020A1  Published: 06/Mar/2008

Title: Aerosol delivery system for dispensing dental compositions

Applicant/Assignee:

Application No.: 11/801831   Filing Date: 11/May/2007

Abstract:

An aerosol delivery system for dispensing a multi-component dental composition is provided. The system is particularly suitable for dispensing dental impression material containing mixed components A and B. The system includes a dispensing device having an inner container with pressurized aerosol chambers. The first chamber is used for storing and dispensing component A, and the second chamber is used for storing and dispensing component B. The dispensing device includes a piston assembly having a first piston member that slides within the first chamber and a second piston member that slides within the second chamber. The pistons force the components into a common manifold, and the combined material is fed into a dispensing tip containing a static mixer, wherein the material is mixed and then dispensed.

Priority: US20060799481P Applic. Date: 2006-05-11

Inventor: PIERSON PAUL R [US]; HARE ROBERT V [US]


Application No.: US20080057000A1  Published: 06/Mar/2008

Title: DENTAL COMPOSITIONS HAVING ANTI-STOKES UP CONVERTERS AND METHODS OF USE

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/931290   Filing Date: 31/Oct/2007

Abstract:

A dental composition can include at least one polymerizable resin and at least one anti-stokes up converter. Alternatively, a two-part composition can include at least one dental composition configured for placement onto a person's tooth, and at least one anti-stokes up converter to be combined with the at least one dental composition. The dental composition can be formulated to blend with a person's tooth, and also be capable of changing color to be distinguishable from the tooth when exposed to long wavelength light. The dental composition can be used in a method for performing a dental procedure by applying the dental composition to a tooth, and exposing the dental composition to long wavelength light. Accordingly, the dental composition can aid a dental professional in distinguishing between the location of the dental composition and the tooth.

Priority: US2005-066013 Applic. Date: 2005-02-25

Inventor: LOVERIDGE DAN [US]


Application No.: US20080057005A1  Published: 06/Mar/2008

Title: HYDROGELS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS

Applicant/Assignee:

Application No.: 11/851106   Filing Date: 06/Sep/2007

Abstract:

The present invention relates to the formation of hydrogels based on guanosine hydrazide derivatives in the presence of cations. The hydrogels can be used as a carrier/delivery system for biologically active substances such as flavors, fragrances, insect attractants or repellents, bactericides, fungicides, pharmaceuticals or agrochemicals.

Priority: WO2005IB00815 Applic. Date: 2005-03-24; WO2006IB50876 Applic. Date: 2006-03-22

Inventor: LEHN JEAN-MARIE [FR]; SREENIVASACHARY NAMPALLY [FR]; HERRMANN ANDREAS [CH]


Application No.: US20080057007A1  Published: 06/Mar/2008

Title: ORAL HYGIENE PRODUCTS CONTAINING ASCORBIC ACID AND METHOD OF USING THE SAME

Applicant/Assignee: DENTECH, INC

Application No.: 11/874637   Filing Date: 18/Oct/2007

Abstract:

The present invention is directed to dental compositions, including dentifrices, containing ascorbic acid for removing and inhibiting dental biofilms which form plaque and tartar, and also for treating and preventing gingivitis and periodontitis. The ascorbic acid composition can contain may additional ingredients, including an enamel-strengthening component, and be used in many different forms, including breath spray, chewing gum, dental floss, dental powder, gargle, lozenge, mouth spray, mouth wash, tooth gel, tooth liquid, tooth paste and tooth strips. Also described in a method of using a dental composition containing ascorbic acid in order to treat plaque and tartar as well as gum disorders.

Priority: US2006-365167 Applic. Date: 2006-03-01

Inventor: LEONHARDT CHARLES [US]; BUSBY JOHN C [US]


Application No.: US20080057064A1  Published: 06/Mar/2008

Title: Erbb3 Based Methods and Compositions for Treating Neoplasms

Applicant/Assignee: ZENSUN (SHANGHAI) SCIENCE AND TECHNOLOGY LIMITED

Application No.: 10/516759   Filing Date: 26/Mar/2003

Abstract:

The present invention relates to compositions and methods for treating neoplasms in mammals, particularly humans. More particularly, the present invention provides for methods for preventing, treating or delaying neoplasm in a mammal using an ErbB-3 protein, a nucleic acid encoding an ErbB-3 protein or a functional fragment thereof. The present invention also provides for isolated nucleic acids encoding an extracellular domain of the ErbB-3 protein, or a functional fragment thereof, substantially purified extracellular domain of the ErbB-3 protein, or a functional fragment thereof and antibodies that bind to an epitope in an extracellular domain of the ErbB-3 protein, or a functional fragment thereof. The present invention further provides for pharmaceutical compositions and/or vaccines comprising the extracellular domain of the ErbB-3 protein, or a functional fragment thereof, or nucleic acids encoding and antibodies binding to such extracellular domain or functional fragments thereof.

Priority: CN20021016259 Applic. Date: 2002-03-26; WO2003CN00217 Applic. Date: 2003-03-26

Inventor: ZHOU MINGDONG [CN]


Application No.: US20080057092A1  Published: 06/Mar/2008

Title: Dental whitening strips

Applicant/Assignee: CREATIVE SPECIALITY PRODUCTS, LLC

Application No.: 11/891730   Filing Date: 13/Aug/2007

Abstract:

A dental whitening strip which includes a carrier support having a whitening composition adhered to said carrier where the whitening composition comprises (a) dextrin

(b) a peroxide

(c) a non-toxic water soluble inorganic salt

(d) a acceptable hydroxy compound which is a plasticizer.

Priority: US20060839027P Applic. Date: 2006-08-21

Inventor: DRONZEK PETER J JR [US]; GROSS LEONARD B [US]; FERNANDEZ LESLIE U [US]


Application No.: US20080057112A1  Published: 06/Mar/2008

Title: Oral Products

Applicant/Assignee: BIOTEC FILMS, LLC

Application No.: 11/596630   Filing Date: 17/May/2005

Abstract:

An apparatus and method for forming a polymer film and/or oral dosage form having an active, content such as a vitamin, that is a considerable or relatively high proportion of the total dry weight percent without being unpleasant to taste, leaving a bitter after taste, having poor mouth feel and/or being slow to dissolve.

Priority: US20040571949P Applic. Date: 2004-05-17; WO2005US17287 Applic. Date: 2005-05-17

Inventor: KNOOP HENRY [US]; SCHANEVILLE TARA [US]


Application No.: US20080057119A1  Published: 06/Mar/2008

Title: COMPOSITIONS AND METHODS FOR TREATING MIDDLE-OF-THE NIGHT INSOMNIA

Applicant/Assignee:

Application No.: 11/833507   Filing Date: 03/Aug/2007

Abstract:

The present invention provides compositions and methods for treating middle-of-the-night insomnia without residual sedative effects upon awakening by administering low doses (about 5 mg or less) of zolpidem or a salt thereof.

Priority: US2006-606640 Applic. Date: 2006-11-29; WO2006US20502 Applic. Date: 2006-05-23; US2006-439873 Applic. Date: 2006-05-23; US2006-440410 Applic. Date: 2006-05-23; US2006-439874 Applic. Date: 2006-05-23; US2006-439884 Applic. Date: 2006-05-23; US20050684842P Applic. Date: 2005-05-25; US20050741673P Applic. Date: 2005-12-01; US20060788340P Applic. Date: 2006-03-31; US20060788249P Applic. Date: 2006-03-31

Inventor: SINGH NIKHILESH N [US]; PATHER SATHASIVAN I [US]


Application No.: US20080057155A1  Published: 06/Mar/2008

Title: INDULGENT GUM BASE AND CHEWING GUM COMPOSITIONS CONTAINING SAME

Applicant/Assignee: CADBURY ADAMS USA LLC

Application No.: 11/846728   Filing Date: 29/Aug/2007

Abstract:

The present invention includes gum base compositions and/or chewing gum compositions that impart a perceptible creaminess upon consumption. The gum base and/or chewing gum compositions include an elastomer, a gum resin or ester thereof and a low-melting pointing fat. In some embodiments, the gum base and/or chewing gum compositions may contain sufficient that to provide a creamy and/or juicy perception during consumption. In some embodiments, the gum base and/or chewing gum compositions may maintain sufficient fat to retain cohesive integrity during consumption. Also included are chewing gum products employing the gum base and/or chewing gum compositions, as well as methods of preparing and using same.

Priority: US20060840905P Applic. Date: 2006-08-29

Inventor: LUO SHIUH [US]; VISSCHER GLENN [US]; MCCORMICK DEMETRIUS TORINO [US]


Application No.: US20080057469A1  Published: 06/Mar/2008

Title: Dental Instrument

Applicant/Assignee: DISCUS DENTAL, LLC

Application No.: 11/927349   Filing Date: 29/Oct/2007

Abstract:

An active dental tool including a vibratory mechanism and a power storage reservoir. The vibratory mechanism includes an electrical motor and an elliptical load. The elliptical load is adapted to be rotated by the motor and to thereby impart an oscillatory motion to a tooth-contacting portion of the dental tool.

Priority: US2005-230710 Applic. Date: 2005-09-19; US20040612283P Applic. Date: 2004-09-21; US20040612006P Applic. Date: 2004-09-21; US20040624833P Applic. Date: 2004-11-03; US20040624840P Applic. Date: 2004-11-03

Inventor: HAYMAN ROBERT [US]; ROSENBLOOD KEN [US]


Application No.: US20080057531A1  Published: 06/Mar/2008

Title: SYSTEMS, KITS, AND METHODS FOR DETECTING CARIOGENIC BACTERIA AND ASSESSING RISK OF DENTAL CARIES

Applicant/Assignee: OREGON HEALTH AND SCIENCE UNIVERSITY

Application No.: 11/835411   Filing Date: 07/Aug/2007

Abstract:

Provided are systems, kits, and methods for the detection and identification of cariogenic bacteria in dental plaque and for assessing the risk in a patient of development dental caries based upon the presence of cariogenic bacteria.

Priority: US20060821672P Applic. Date: 2006-08-07

Inventor: MACHIDA CURTIS A [US]; MAIER TOM [US]


Application No.: US20080058401A1  Published: 06/Mar/2008

Title: COMPOUNDS THAT INHIBIT TRPV1 AND USES THEREOF

Applicant/Assignee: ABBOTT LABORATORIES

Application No.: 11/844712   Filing Date: 24/Aug/2007

Abstract:

Compounds of formula (I) wherein R3, R7, R9 and L are defined in the description are TRPV1 antagonists that exhibit low inhibitory activity against CYP3A4. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

Priority: US20060840254P Applic. Date: 2006-08-25

Inventor: LEE CHIH-HUNG [US]; PERNER RICHARD J [US]; BROWN BRIAN S [US]; DARBYSHIRE JOHN [CH]


Application No.: US20080058442A1  Published: 06/Mar/2008

Title: Two-Step System For Improved Initial And Final Characteristics Of A Biomaterial

Applicant/Assignee:

Application No.: 10/577277   Filing Date: 29/Oct/2004

Abstract:

A two-step system for chemically bonded ceramic (CBC) materials, and especially a dental filling material or an implant material. The system includes an initial working part-system to provide for improved early-age properties and a second main system to provide for improved end-product properties including bioactivity. The systems interact chemically. The invention also relates to the powdered materials and the hydration liquid, respectively, as well as the formed ceramic material.

Priority: SE20030002844 Applic. Date: 2003-10-29; SE20040001026 Applic. Date: 2004-04-22; WO2004SE01577 Applic. Date: 2004-10-29

Inventor: HERMANSSON LEIF [SE]; ENGQVIST HAKAN [SE]; SPENGLER HAKAN [SE]


Application No.: US20080060664A1  Published: 13/Mar/2008

Title: Device For Filtering Second-Hand Smoke

Applicant/Assignee:

Application No.: 11/530233   Filing Date: 08/Sep/2006

Abstract:

A device for filtering second-hand smoke from a burning tobacco product includes a first chamber for receiving the lit end of the tobacco product. Users of the device can inhale smoke from the tobacco product through a first aperture in the first chamber, while a filter communicating with the first chamber filters smoke from the burning end of the tobacco product. A second chamber is configured to receive smoke and air exhaled by the user. The smoke is filtered by the second filter and the filtered air is passed through to the surrounding environment.

Priority:

Inventor: RICHARDS WILBUR [US]


Application No.: US20080060671A1  Published: 13/Mar/2008

Title: Cleaning and drying system for a personal hygiene device

Applicant/Assignee:

Application No.: 11/899774   Filing Date: 07/Sep/2007

Abstract:

An apparatus, system and method to clean and dry a personal hygiene device, such as a razor, tweezers, a comb, a toothbrush or other dental apparatuses, such as a dental pick. Typically, the system includes dryer generally coupled to a curved-wall chamber. The dryer generally includes a housing coupled to a duct, which, in turn is coupled to the curved-wall chamber. The housing includes a fan for pulling intake air into a housing via an air-intake. The housing further may include a heating element for heating air before entry into the curved-wall chamber. Thus, a personal hygiene device placed into a curved-wall chamber having a cleaning fluid can advantageously be cleaned and dried via circulating heated air and fluid within the curved-wall chamber under the circulation force of air provided by the fan.

Priority: US20060824860P Applic. Date: 2006-09-07

Inventor: RUFFIN STEPHEN [US]


Application No.: US20080060675A1  Published: 13/Mar/2008

Title: Method and apparatus for dispensing oral hygiene products

Applicant/Assignee:

Application No.: 11/518769   Filing Date: 11/Sep/2006

Abstract:

A method and apparatus for cleansing a person's mouth. One aspect is an apparatus comprising at least one teeth cleaning tool, a volume of mouth rinse and a container. The container comprises at least one first chamber that is liquid-tight and has the volume of mouth rinse disposed therein. The container further comprises at least one second chamber having the at least one teeth cleaning tool at least partially disposed therein.

Priority:

Inventor: KEISER RICHARD G [US]; ANGILERI PHILIP J [US]


Application No.: US20080061089A1  Published: 13/Mar/2008

Title: Dispensing Fluids From Containers Using Self Closing Valve, Typically Duckbill Type Valve

Applicant/Assignee:

Application No.: 11/575787   Filing Date: 11/Oct/2005

Abstract:

A dispenser for dispensing a fluid from a container T having an inlet for mounting to the container so as to receive therethrough the fluid, and an outlet which is adapted to open to release fluid therefrom when a predetermined pressure is applied to the fluid in the dispenser at the outlet, and to close to retain fluid in the dispenser at a pressure less than the predetermined pressure. A wall of resilient material at the outlet has one or more panels of elastomeric material provided therein, each panel being deformable to enable the adjacent resilient material to flex at the predetermined pressure and thus enable the outlet to open.

Priority: AU20040905861 Applic. Date: 2004-10-11; WO2005AU01578 Applic. Date: 2005-10-11

Inventor: WELLMAN CRAIG J [AU]


Application No.: US20080063611A1  Published: 13/Mar/2008

Title: Dentifrice Compositions

Applicant/Assignee: DEN-MAT HOLDINGS LLC

Application No.: 11/851715   Filing Date: 07/Sep/2007

Abstract:

Stain-removal, desensitizing, anti-tartar and anti-gingivitis dentifrice compositions. The dentifrices comprise a fluoride agent

an abrasive agent

a proteolytic agent

a foaming agent

a sweetening/flavoring agent

an emulsifying agent

either desensitizing, anti-tartar or anti-gingivitis agents or combinations thereof

and a delivery agent. The dentifrices are visually pleasing and impart a soothing sensation during and after brushing.

Priority: US20060843699P Applic. Date: 2006-09-12

Inventor: IBSEN ROBERT L [US]; MATHEWS ALAN B [US]


Application No.: US20080063612A1  Published: 13/Mar/2008

Title: Dental Whitening Compositions

Applicant/Assignee: DISCUS DENTAL, LLC

Application No.: 11/927471   Filing Date: 29/Oct/2007

Abstract:

A two-component whitening system has a de-sensitizing effect as well as re-mineralizing capability. The system may be an unfoamed, a foamed or a foamable composition. The system has a first component with at least one peroxide compound, at least one source of phosphate and at least one gelling agent

and a second component with at least one source of calcium, strontium and/or mixtures thereof. The second component may also contain at least one gelling agent, and the composition maybe present as a foam or is foamable. The composition may be packed in a two-compartment syringe.

Priority: US2005-271412 Applic. Date: 2005-11-09; US20040626407P Applic. Date: 2004-11-09; US20040631121P Applic. Date: 2004-11-26; US20050646309P Applic. Date: 2005-01-22; US20050653421P Applic. Date: 2005-02-15

Inventor: MACDONALD JEFF [US]; QUAN NANCY N [US]; HAYMAN ROBERT [US]


Application No.: US20080063713A1  Published: 13/Mar/2008

Title: Particulate form of a pharmaceutical composition which is easy to swallow

Applicant/Assignee:

Application No.: 11/516573   Filing Date: 07/Sep/2006

Abstract:

The present invention relates to a pharmaceutical composition for direct oral administration which is very easy to swallow especially for young children, comprising at least one pharmaceutically active compound. The pharmaceutical composition is present in the form of one or more particles. The particles comprise a core containing the active ingredient which has been provided with one or more coatings. The pharmaceutical composition is preferably administered in combination with a powder and/or granules which, when applied to the tongue, spontaneously generate additional saliva. With the extra saliva, the coated particles form a soft, smooth, but mechanically stable surface perceived as pleasant in the mouth within seconds so that they may be swallowed easily and practically in the right quantity with the extra saliva formed.

Priority:

Inventor: GRUBER PETER [DE]; KRAAHS PETER [DE]


Application No.: US20080063747A1  Published: 13/Mar/2008

Title: DUSTING COMPOSITIONS FOR CHEWING GUM PRODUCTS

Applicant/Assignee: CADBURY ADAMS USA LLC

Application No.: 11/840729   Filing Date: 17/Aug/2007

Abstract:

The present application relates to compositions for dusting chewing gum products and chewing gum products incorporating same. The dusting compositions have a managed release profile. The compositions generally include a dusting component, which is at least partially encapsulated with an encapsulating material. The compositions also may include an unencapsulated dusting component. The present invention also includes dusted chewing gum products, such as center-fill, compressed or candy gum, and methods of making same.

Priority: US2005-205874 Applic. Date: 2005-08-17; US2004-955149 Applic. Date: 2004-09-30; US2004-955225 Applic. Date: 2004-09-30; US2006-415043 Applic. Date: 2006-05-01; US2005-210954 Applic. Date: 2005-08-24; US2004-925822 Applic. Date: 2004-08-25; US2006-415044 Applic. Date: 2006-05-01; US2006-415006 Applic. Date: 2006-05-01; US2006-415012 Applic. Date: 2006-05-01; WO2006US19879 Applic. Date: 2006-05-19; US20060776699P Applic. Date: 2006-02-24; US20050683634P Applic. Date: 2005-05-23; US20050650758P Applic. Date: 2005-02-07; US20060838524P Applic. Date: 2006-08-17

Inventor: BOGHANI NAVROZ [US]; GEBRESELASSIE PETROS [US]; JANI BHARAT [US]; KABSE KISHOR [US]; GRANT R S [US]; KIEFER JESSE [US]; KUNCEWITCH THOMAS [US]; KRAMER COLLEEN [US]; ROBINSON MARY K [US]; SCHMITZ KRISTEN [US]; LUO SHIUH J [US]


Application No.: US20080063997A1  Published: 13/Mar/2008

Title: LIGHTED DENTAL CLEANER

Applicant/Assignee:

Application No.: 11/465603   Filing Date: 18/Aug/2006

Abstract:

A dental cleaning device includes a handle portion and a cover portion. The handle portion provides a dental cleaning tool, such as a dental pick or a dental scaler, and an illumination source, such as one or more light emitting diodes (LEDs). The illumination source directs light toward the end of the dental cleaning tool so that the light is always pointed exactly where it is needed during a dental cleaning procedure. The cover portion may include a mirror which further aids a user in viewing the dental cavity while using the dental cleaning tool. The cover portion is configured to attach to the handle portion to enclose the dental cleaning tool when the dental cleaning tool is not in use.

Priority:

Inventor: JANSHESKI JOHN M [US]; SHANKLE LEX [US]


Application No.: US20080063999A1  Published: 13/Mar/2008

Title: Tooth Whitening Lens with Bite Plate

Applicant/Assignee:

Application No.: 11/632561   Filing Date: 15/Jul/2005

Abstract:

A teeth whitening device having a lens which fits against the teeth. The lens has a casing containing a plurality of light emitting diodes which project light into the lens. The lens filters the light to produce a 430 to 450 nanometer blue light which is projected onto the surface of the teeth. When carbamide peroxide is placed on the surface of the teeth the blue light will activate the peroxide to whiten the teeth several shades within one hour without heating or sensitizing the teeth. The lens has a bite plate which a user bites down on to keep the lens in position against the teeth, leaving the user's hands free. The device and method are safe enough for use outside the dental office.

Priority: US20040588418P Applic. Date: 2004-07-16; WO2005US25295 Applic. Date: 2005-07-15

Inventor: OSBORN JOYCE A [US]


Application No.: US20080064001A1  Published: 13/Mar/2008

Title: Retracting Devices

Applicant/Assignee: DISCUS DENTAL, LLC

Application No.: 11/929140   Filing Date: 30/Oct/2007

Abstract:

The present invention relates to a retracting device for retracting at least a portion of a user's mouth. The retracting device includes formations, which may be inter-engaging and/or non-inter-engaging with other dental tools or apparatus. The formations are adapted for repeatably positioning a subject's mouth with respect to a light system, and/or an imaging film, and/or a dental tray.

Priority: US2005-173297 Applic. Date: 2005-06-30; US20050220642F Applic. Date: 2005-01-04; US20050220680F Applic. Date: 2005-01-04; US20050220679F Applic. Date: 2005-01-04; US20050220712F Applic. Date: 2005-01-04; US20050232670F Applic. Date: 2005-06-22; US20050232671F Applic. Date: 2005-06-22; US20040585224P Applic. Date: 2004-07-02; US20050594327P Applic. Date: 2005-03-30; US20050594297P Applic. Date: 2005-03-25; US20050664696P Applic. Date: 2005-03-22; US20050658517P Applic. Date: 2005-03-03; US20050647580P Applic. Date: 2005-01-26; US20050647593P Applic. Date: 2005-01-26; US20050647612P Applic. Date: 2005-01-26; US20050647725P Applic. Date: 2005-01-26; US20050641462P Applic. Date: 2005-01-04; US20050641461P Applic. Date: 2005-01-04; US20050641469P Applic. Date: 2005-01-04; US20050641468P Applic. Date: 2005-01-04; US20040631267P Applic. Date: 2004-11-26; US20040604577P Applic. Date: 2004-08-25

Inventor: DORFMAN WILLIAM [US]; HAYMAN ROBERT [US]; ROSE ERIC P [US]; SCHROEDER DENNIS [US]; PIOREK STEVE [US]; QUAN NANCY N [US]; KARTEN STUART [US]; ROSENBLOOD KENNETH [US]


Application No.: US20080064003A1  Published: 13/Mar/2008

Title: Dental Matrix Devices And A Seamless, Single Load Cavity Preparation And Filling Technique

Applicant/Assignee:

Application No.: 11/834945   Filing Date: 07/Aug/2007

Abstract:

There are disclosed methods for the restoration of a decayed portion of a tooth, and dental matrices, dental wedges, interdental matrix stabilizers, dental separator rings, dental curing light devices, and kits that can be used in the methods for the restoration of a decayed portion of a tooth.

Priority: US20060844333P Applic. Date: 2006-09-13; US20070887291P Applic. Date: 2007-01-30

Inventor: CLARK DAVID J [US]


Application No.: US20080064004A1  Published: 13/Mar/2008

Title: Dental Kits And A Seamless, Single Load Cavity Preparation And Filling Technique

Applicant/Assignee:

Application No.: 11/834993   Filing Date: 07/Aug/2007

Abstract:

There are disclosed methods for the restoration of a decayed portion of a tooth, and dental matrices, dental wedges, interdental matrix stabilizers, dental separator rings, dental curing light devices, and kits that can be used in the methods for the restoration of a decayed portion of a tooth.

Priority: US20060844333P Applic. Date: 2006-09-13; US20070887291P Applic. Date: 2007-01-30

Inventor: CLARK DAVID J [US]


Application No.: US20080064642A1  Published: 13/Mar/2008

Title: Peptidic And Peptidoid Bradykinin B1 Receptor Antagonists And Uses Thereof

Applicant/Assignee: UNIVERSITE DE SHERBROOKE

Application No.: 11/660436   Filing Date: 19/Aug/2005

Abstract:

The present invention provides for new peptidic and peptidoid Bradykinin B1 receptor antagonists of formula (1) having good to excellent affinities and selectivity for the BKB1 receptor, and increased resistance to enzymatic degradation, superior pharmacokinetic properties, both in vitro and in vivo, with capability to significantly prevent and treat conditions wherein BKB1Rs are induced and over-expressed.

Priority: US20040602626P Applic. Date: 2004-08-19; WO2005CA01268 Applic. Date: 2005-08-19

Inventor: GUERIN BRIGITTE [CA]; BATTISTINI BRUNO [CA]; GOBEIL FERNAND [CA]; NANTEL FRANCOIS [CA]; NEUGEBAUER WITOLD [CA]; PLANTE GERARD [CA]; REGOLI DOMENICO [CA]; SIROIS PIERRE [CA]


Application No.: US20080065250A1  Published: 13/Mar/2008

Title: Automatic Plant for the Treatment and Packing of Meat Product

Applicant/Assignee:

Application No.: 11/596377   Filing Date: 12/May/2005

Abstract:

The invention relates to an automatic plant for the treatment and packing of meat product, comprising an injection station for injecting brine into a meat product, first and second maceration stations for macerating the injected meat product, and a packing station for packing the treated meat product. The injection station is connected to said first and second maceration stations by an accumulating and loading unit for accumulating meat product coming from the injection station and selectively loading it into the first and second maceration stations which are connected to the packing station by means of a transfer unit adapted for transferring the meat product from the first and second maceration stations to feed hoppers for feeding the packing station. The plant is controlled by computerized control.

Priority: WO2005ES00257 Applic. Date: 2005-05-12; ES20040001246 Applic. Date: 2004-05-14

Inventor: LAGARES COROMINAS NARCIS [ES]


Application No.: US20080066209A1  Published: 20/Mar/2008

Title: Protective face mask

Applicant/Assignee: KREAPS APS

Application No.: 11/896127   Filing Date: 29/Aug/2007

Abstract:

A protective face mask comprising: an eye-protecting shield made essentially from a plastics material, the eye-protecting shield being dimensioned to cover at least the eye portions of a human wearer, the eye-protecting shield having a perimeter defining a first surface facing the wearer's face, and a second surface facing away from the wearer's face

an adhesive forming an adhesive strip attached to the first surface of the eye-protecting shield for providing a substantially watertight and releasable sealing engagement between at least a portion of the perimeter forming an upper edge of the face mask and at least a portion of the skin of the wearer's face, wherein the upper part of the perimeter of the mask is provided with a continuous layer of adhesive along the perimeter, and the lower part of the perimeter of the mask is free of adhesive, the lower part of the perimeter forms a bottom edge of the mask being provided with at least one part forming a projection offset from the centre line of the mask, and wherein the mask extends along the contour of the wearer's face from the forehead to cheekbones and the lower perimeter thereof extends above the mouth provides a comfortable and flexible mask without the need for straps,

elastic bands or side bars, avoids pressure on the skin in the contact zone, allows free eye movement and airflow and minimizes the formation of dew.

Priority: EP20060017965 Applic. Date: 2006-08-29; US20060840691P Applic. Date: 2006-08-29

Inventor: KAYEROD HELLE [DK]


Application No.: US20080066781A1  Published: 20/Mar/2008

Title: Stripe removal system

Applicant/Assignee:

Application No.: 11/835642   Filing Date: 08/Aug/2007

Abstract:

A system for removing paint and other coatings from hard surfaces is mounted on a truck for over-the-road travel. The truck bed carries a high power vacuum pump, a self propelled tractor with an attached blast head, a liquid reservoir, a sump or vacuum tank, and a ramp for loading the tractor. The reservoir is connected to a low pressure pump that transfers water to the high pressure pump. The high pressure pump is connected to the blast head by a high pressure hose. A vacuum hose is connected to the sump which has an internal enclosure for separating the waste materials from the liquid for easy dumping of semi dried materials.

Priority: US2004-884643 Applic. Date: 2004-07-02

Inventor: CROCKER JAMES P [US]


Application No.: US20080069779A1  Published: 20/Mar/2008

Title: Foamable vehicle and vitamin and flavonoid pharmaceutical compositions thereof

Applicant/Assignee: FOAMIX LTD

Application No.: 11/900072   Filing Date: 10/Sep/2007

Abstract:

Vitamin and flavonoid containing compositions are provided that are stable to degradation. Stabilized compositions include one or more features including a hygroscopic solvent at a sufficient concentration to provide an Aw value of the hygroscopic vitamin and or flavonoid containing composition of less than 0.9, antioxidant flavonoids that are preferentially oxidized before the vitamin, preservatives, and hydrocarbon propellants selected to reduce the oxidation potential of the composition.

Priority: US2006-430599 Applic. Date: 2006-05-09; US2004-835505 Applic. Date: 2004-04-28; US20060843140P Applic. Date: 2006-09-08; US20060784793P Applic. Date: 2006-03-21; US20050679020P Applic. Date: 2005-05-09; US20030530015P Applic. Date: 2003-12-16; US20030492385P Applic. Date: 2003-08-04

Inventor: TAMARKIN DOV [IL]; FRIEDMAN DORON [IL]; EINI MEIR [IL]; BERMAN TAL [IL]; SCHUZ DAVID [IL]


Application No.: US20080069782A1  Published: 20/Mar/2008

Title: METHOD OF INHIBITING BACTERIAL GROWTH AND BIOFILM FORMATION WITH NATURAL QUORUM SENSING PEPTIDES

Applicant/Assignee: UNIVERSITY OF SOUTHERN CALIFORNIA

Application No.: 11/561275   Filing Date: 17/Nov/2006

Abstract:

Methods for selectively manipulating a growth rate of a selected bacterium comprising the step of contacting the selected bacterium with a predetermined amount of a quorum sensing molecule to affect a change in the growth rate of the selected bacterium, wherein the quorum sensing molecule is species specific, and the change in the growth rate is dependent on the amount of quorum sensing molecule in a dose-dependent fashion. Also provided are methods for treating or protecting against bacterial infections by utilizing the dose-dependent response of bacterial quorum sensing systems. The methods can be applied to a wide range of bacteria species including Streptococci, Staphylococci, and Bacilli. Compositions, medicaments and oral formulations for use with the methods are also disclosed.

Priority: US20050738361P Applic. Date: 2005-11-17

Inventor: GOODMAN STEVEN D [US]; KAY OLGA [US]; SHI WENYUAN [US]; QL FENGXIA [US]


Application No.: US20080069841A1  Published: 20/Mar/2008

Title: Pharmaceutical Compositions Containing Botulinum Neurotoxin A2

Applicant/Assignee:

Application No.: 11/659448   Filing Date: 03/Aug/2005

Abstract:

A composition, medicament or use, comprising or consisting of botulinum toxin type A2 and a surfactant, having one or more or all of the characteristics select from the group consisting of

(a) a much longer duration of action

(b) a much faster rate of onset of muscular paralysis

(c) a significantly greater intramuscular safety margin

(d) a selective action on inhibition of skeletal muscle contraction

(e) a selective action on inhibition of pain-related (nociceptive) nerve cell function: Wherein each characteristic is determined comparative to the same characteristic effect of botulinum toxin type A1.

Priority: GB20040017367 Applic. Date: 2004-08-04; GB20040021290 Applic. Date: 2004-09-24; GB20040021288 Applic. Date: 2004-09-24; GB20040023952 Applic. Date: 2004-10-28; GB20040023953 Applic. Date: 2004-10-28; WO2005GB03036 Applic. Date: 2005-08-03

Inventor: PANJWANI NAVEED [GB]; WEBB PAUL [GB]; PICKETT ANDY [GB]


Application No.: US20080069863A1  Published: 20/Mar/2008

Title: Device for treatment of disorders in the oral cavity with nitric oxide, and manufacturing process for the same

Applicant/Assignee:

Application No.: 11/891674   Filing Date: 10/Aug/2007

Abstract:

A device and method for therapeutical treatment of disorders in the oral cavity and a process for manufacturing of said device is disclosed. The device comprises a nitric oxide (NO) eluting polymer. The nitric oxide (NO) eluting polymer is configured to elute a therapeutic dosage of nitric oxide (NO) when used in the oral cavity. The device allows for target treatment of infections or wounds in the oral cavity. The device comprising the nitric oxide (NO) eluting polymer is arranged to contact an infected area in the oral cavity, such that a therapeutic dose of nitric oxide is eluted from said nitric oxide eluting polymer to said area. The nitric oxide (NO) eluting polymer is integrated with a carrier material, such that said carrier material, in use, regulates and controls the elution of said therapeutic dosage of nitric oxide (NO).

Priority: EP20050002937 Applic. Date: 2005-02-11; WO2006EP50888 Applic. Date: 2006-02-13; US20050652758P Applic. Date: 2005-02-14

Inventor: PETERS TOR [SE]


Application No.: US20080069876A1  Published: 20/Mar/2008

Title: Method for preparing solid dosage forms that form a paste, cream or gel when diluted for final use

Applicant/Assignee:

Application No.: 11/901120   Filing Date: 14/Sep/2007

Abstract:

Solid compositions capable of forming a paste, cream or gel suitable for use as a personal hygiene product when diluted with a liquid are disclosed. Methods of making and using solid compositions capable of forming a paste, cream or gel suitable for use as a personal hygiene product when diluted with a liquid are also disclosed.

Priority: US20060825698P Applic. Date: 2006-09-14

Inventor: MOORE RYAN G [US]


Application No.: US20080069925A1  Published: 20/Mar/2008

Title: VITAMIN D COMPOSITIONS AND METHOD OF ADMINISTRATION TO A HUMAN BEING

Applicant/Assignee:

Application No.: 11/674234   Filing Date: 13/Feb/2007

Abstract:

Composition of vitamin D in medium-chain triglycerides and use thereof in delivering a nutritional or therapeutic amount of vitamin D to a human being, particularly, an infant. The compositions are applied to an object, such as skin or in the case of an infant to a woman's nipple or pacifier from which the infant sucks off the composition. The method provides a more suitable, safer and efficient way of providing the human being with vitamin D. The compositions further comprise a free fatty acid and/or monoglyceride, oxidant preservative and, optionally, other vitamins.

Priority: CA20062558202 Applic. Date: 2006-09-14

Inventor: VIETH REINHOLD W [CA]; VIETH ELAINE [CA]


Application No.: US20080070058A1  Published: 20/Mar/2008

Title: Palladium-cobalt based alloys and dental articles including the same

Applicant/Assignee: IVOCLAR VIVADENT, INC

Application No.: 11/892933   Filing Date: 28/Aug/2007

Abstract:

An alloy is provided based on a palladium-cobalt binary system, has a coefficient of thermal expansion (CTE) of about 14.0 to about 15.5 and may include one or more of the following additive metals: aluminum, boron, chromium, gallium, lithium, rhenium, ruthenium, silicon, tantalum, titanium, and tungsten.

Priority: US20060844672P Applic. Date: 2006-09-15

Inventor: DASGUPTA TRIDIB [US]; INGERSOLL CLYDE [US]; TYSOWSKY GEORGE [US]


Application No.: US20080070187A1  Published: 20/Mar/2008

Title: Dispenser for dental compositions

Applicant/Assignee: BISCO, INC

Application No.: 11/522825   Filing Date: 14/Sep/2006

Abstract:

The present invention relates to an apparatus for providing specifically metered doses of at least two flowable dental materials in desired ratios to one another. In particular, the present invention allows for controlled metering and dispensing of two or more flowable dental substances which when subsequently mixed form a dental bonding composition, dental adhesive, dental cement, or other dental restorative or preparative materials.

Specifically, one embodiment of the present invention utilizes a multi-rack system as well as a drive spring action to provide a substantial mechanical advantage to the user such that a relatively long throw of the dispensing button creates a relatively short, metered distance of movement of the multiple racks and corresponding pistons in the each lumen of a cartridge containing the component of the desired dental composition, allowing for small, metered doses of each flowable dental component to be dispensed from the apparatus in the proper proportions.

Priority:

Inventor: MULHAUSER PAUL [US]; KIRK KARL D [US]; CZARNECKI DAVID [US]; NAGEL RICHARD [US]


Application No.: US20080070188A1  Published: 20/Mar/2008

Title: Disposable dental prophylaxis apparatus capable of discharging predetermined amount of dentifrice material therefrom

Applicant/Assignee:

Application No.: 11/602094   Filing Date: 21/Nov/2006

Abstract:

The present invention relates to a disposable dental prophylaxis apparatus capable of discharging a predetermined amount of dentifrice material therefrom, including: a housing having a drain hole adapted for discharging a dentifrice material therefrom, a tube room adapted for mounting a dentifrice material-charging tube therein, and a link room having a plurality of teeth formed along the both inner wall surfaces for adjustably discharging the dentifrice material in predetermined amounts from the tube

a wheel gear having a drain hole adapted for inducing the dentifrice material flowing from the drain hole of the housing to a wheel cup adapted for rubbing against a patient's tooth

the wheel cup having a drain hole formed for receiving the dentifrice material induced from the drain hole of the wheel gear

the tube adapted to be charged with the dentifrice material and having a plurality of folds adapted to be compressed gradually as the dentifrice material is discharged therefrom in the predetermined amounts

and a link adapted for compressing the tube such that the dentifrice material is discharged from the tube.

Priority: KR20060089786 Applic. Date: 2006-09-15

Inventor: LEE KWANG S [US]


Application No.: US20080070191A1  Published: 20/Mar/2008

Title: Method for Forming Polychromatic Pressable Porcelain Dental Restoration

Applicant/Assignee: DEN-MAT CORPORATION

Application No.: 11/840803   Filing Date: 17/Aug/2007

Abstract:

A method for forming a polychromatic pressable porcelain dental restoration. A wax model of the dental restoration is prepared as is commonly used in the lost wax technique. Chards or pieces of porcelain are embedded into the wax model. The porcelain embedded wax model is then used in the common pressable porcelain technique to form a polychromatic porcelain dental restoration with natural tooth shading.

Priority: US20060841539P Applic. Date: 2006-09-01

Inventor: RICKS SEAN [US]


Application No.: US20080070192A1  Published: 20/Mar/2008

Title: Palladium-cobalt based alloys for dental prestheses including porcelain fused to metal

Applicant/Assignee: IVOCLAR VIVADENT, INC

Application No.: 11/543917   Filing Date: 06/Oct/2006

Abstract:

An alloy s provided for dental prostheses including porcelain fused to metal (PFM) restorations. The alloy is grey in color with an oxide coating for bonding porcelain to the oxidized cast alloy substrate. The alloy has suitable mechanical properties for cast prostheses and for the support of the porcelain and is readily polished to a bright sheen. The alloy is based on a palladium-cobalt binary system, has a coefficient of thermal expansion (CTE) in the range of about 14.0 to 15.3 and may include one or more of the following additive metals: aluminum, boron, chromium, gallium, lithium, rhenium, ruthenium, silicon, tantalum, titanium, and tungsten.

Priority: US20060844672P Applic. Date: 2006-09-15

Inventor: DASGUPTA TRIDIB [US]; INGERSOLL CLYDE [US]; TYSOWSKY GEORGE [US]


Application No.: US20080070193A1  Published: 20/Mar/2008

Title: Dental Composition Containing Unsaturated Carbosilane Containing Components

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/572071   Filing Date: 14/Jul/2004

Abstract:

The invention relates to a dental composition comprising a) carbosilane containing component (A) comprising at least 1 Si-Aryl bond, at least 1 silicon atom, at least 2 unsaturated moiety, no Si-Oxygen bond, b) Si-II functional component (B), c) initiator (C), d) optionally filler (D), and e) optionally component (E) selected from modifiers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavourings.

Priority: WO2004EP07788 Applic. Date: 2004-07-14

Inventor: BISSINGER PETER [DE]; ECKERT ADRIAN S [DE]; HECHT REINHARD [DE]; HOHEISEL UWE H [DE]


Application No.: US20080070195A1  Published: 20/Mar/2008

Title: Energetically activated biomedical nanotheurapeutics integrating dental and medical treatments and procedures

Applicant/Assignee:

Application No.: 11/895404   Filing Date: 24/Aug/2007

Abstract:

A method that includes the following effects: the ability to expand, porositize, clean, decontaminate, debride, break-down and/or destroys, or aids and accentuates the dissolution or extraction of biological structures, nerves and tissues. The methodology uses nano-technology and/or other chemistries may or may not be excited by energy sources to expand and porositize the tissue, which enhances the penetration and effectiveness and acceleration of subsequent chemical, mechanical, and/or procedural steps in the protocol or process. Furthermore, the method includes the ability to associate with and/or initiate in the reconstructive growth and healing process associated with healthy tissue after surgery and/or the ability to destroy diseased or necrotic tissues or cells. The method also includes the ability to begin, construct or stage the activation of cells and/or tissues, including the area of transplantation and use in stem or primordial cell accentuation, their attachment and/or stimulation for growth and differentiation.

Priority: US20060840282P Applic. Date: 2006-08-24

Inventor: DIVITO ENRICO E [US]; GLOVER DOUGLAS L [US]; TUBBS KEMMONS [US]


Application No.: US20080070865A1  Published: 20/Mar/2008

Title: TRIPHENYLPHOSPHINE OXIDE DERIVATIVES AND USES THEREOF

Applicant/Assignee: REDPOINT BIO CORPORATION

Application No.: 11/856518   Filing Date: 17/Sep/2007

Abstract:

The present invention is directed to the use of a compound having the formula wherein R<1>, R<2>, R<3>, m, n and p are defined herein. The compounds of the present invention are useful as inhibitors of certain taste perceptions and functions. The invention is also directed to compositions comprising a compound according to the above formula.

Priority: US20060844657P Applic. Date: 2006-09-15

Inventor: PALMER R KYLE [US]; BRYANT ROBERT W [US]; SPROUS DENNIS [US]


Application No.: US20080071347A1  Published: 20/Mar/2008

Title: MEDICAL DEVICES HAVING ALLOY COMPOSITIONS

Applicant/Assignee: BOSTON SCIENTIFIC SCIMED, INC

Application No.: 11/780060   Filing Date: 19/Jul/2007

Abstract:

A medical device includes an alloy having a microstructure that provides desirable properties. The alloy can be a eutectoid composition of e.g. titanium as a major constituent and any combination of iridium, platinum, chromium, gold, silver, bismuth, manganese, palladium, cobalt, copper, iron, and/or nickel as a minor constituent, wherein the alloy forms at least a portion of the medical device.

Priority: US20060844897P Applic. Date: 2006-09-15

Inventor: CAMBRONNE MATTHEW [US]


Application No.: US20080072432A1  Published: 27/Mar/2008

Title: Dispensing Utensil

Applicant/Assignee:

Application No.: 11/771372   Filing Date: 29/Jun/2007

Abstract:

A dispensing utensil 10 comprising: a handle portion 11

an implement portion 12

a cavity 15 for storing dispensable contents, the cavity 15 defined by a first wall means 13, 14 and a second wall means 19 closing the cavity 15

characterised in that a first portion 20 of the first wall means 13, 14 is openable about a hinge formed by the second wall means 19 , thereby allowing the contents to be dispensed.

Priority: WO2004AU01818 Applic. Date: 2004-12-30; AU20040100000 Applic. Date: 2004-01-02

Inventor: TEYS BRADLEY D [AU]; BEVAN GLENN [AU]; MOBBS KEVIN J [AU]


Application No.: US20080075672A1  Published: 27/Mar/2008

Title: Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules

Applicant/Assignee:

Application No.: 11/703610   Filing Date: 06/Feb/2007

Abstract:

Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines.

Priority: US2003-658834 Applic. Date: 2003-09-08; US20030457135P Applic. Date: 2003-03-21; US20020409898P Applic. Date: 2002-09-09

Inventor: GANTIER RENE [FR]; VEGA MANUEL [FR]; DRITTANTI LILA [FR]; GUYON THIERRY [FR]


Application No.: US20080075676A1  Published: 27/Mar/2008

Title: Dental Whitening Systems

Applicant/Assignee: DISCUS DENTAL, LLC

Application No.: 11/927207   Filing Date: 29/Oct/2007

Abstract:

A system and method for tooth whitening are disclosed wherein at least one peroxide-containing gel and at least one transition metal compound- containing gel, particularly at least one lower atomic number transition metal compound, more particularly at least a ferrous compound including gluconate, sulfate, nitrate, acetate or mixtures thereof, are applied to a patient's mouth. Gelling agent is also included. The activation of the peroxide whitens the patient's teeth. The system may be used with or without the application of light. The system further provides an additional gel including a sensitivity reduction compound including potassium nitrate, sodium nitrate or mixtures thereof for possible sensitivity treatment if needed.

Priority: US2005-271283 Applic. Date: 2005-11-09; US20040626407P Applic. Date: 2004-11-09; US20040631121P Applic. Date: 2004-11-26; US20050653421P Applic. Date: 2005-02-15

Inventor: MACDONALD JEFF [US]; LEE ANGELA J [US]; QUAN NANCY N [US]


Application No.: US20080076704A1  Published: 27/Mar/2008

Title: Methods of drug delivery using sulphated chitinous polymers

Applicant/Assignee:

Application No.: 11/899172   Filing Date: 04/Sep/2007

Abstract:

The present invention provides methods and compositions for delivering a therapeutic agent across a membrane that has limited permeability for the therapeutic agent. The method includes delivering the therapeutic agent to the membrane in a composition which includes a sulphated chitinous polymer as a primary carrier.

Priority: US2002-224173 Applic. Date: 2002-08-20

Inventor: KYDONIEUS AGIS [US]; ELSON CLIVE [CA]; THANOU MAYA [GR]


Application No.: US20080076758A1  Published: 27/Mar/2008

Title: Pharmaceutical compounds

Applicant/Assignee: PIRAMED LIMITED GENENTECH, INC

Application No.: 11/789468   Filing Date: 24/Apr/2007

Abstract:

Compounds of Formulae Ia and Ib, and stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula Ia and Ib for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Priority: US20060795048P Applic. Date: 2006-04-26

Inventor: FOLKES ADRIAN [GB]; SHUTTLEWORTH STEPHEN [GB]; CHUCKOWREE IRINA [GB]; OXENFORD SALLY [GB]; WAN NAN CHI [GB]; CASTANEDO GEORGETTE [US]; GOLDSMITH RICHARD [US]; GUNZNER JANET [US]; HEFFRON TIM [US]; MATHIEU SIMON [US]; OLIVERO ALAN [US]; SUTHERLIN DANIEL P [US]; ZHU BING-YAN [US]


Application No.: US20080076768A1  Published: 27/Mar/2008

Title: Pharmaceutical compounds

Applicant/Assignee: PIRAMED LIMITED

Application No.: 11/789423   Filing Date: 24/Apr/2007

Abstract:

A thienopyrimidine of formula (I): and the pharmaceutically acceptable salts thereof have activity as inhibitors of PI3K with selectivity for the P110alpha subtype, and may be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour, particularly those associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine disorders and neurological disorders. Processes for synthesizing the compounds are also described.

Priority: US20060794966P Applic. Date: 2006-04-26

Inventor: CHUCKOWREE IRINA [GB]; FOLKES ADRIAN [GB]; HANCOX TIM [GB]; SHUTTLEWORTH STEPHEN [GB]


Application No.: US20080076847A1  Published: 27/Mar/2008

Title: Polymerizable compositions with acylgermanes as initiatiors

Applicant/Assignee: IVOCLAR VIVADENT AG

Application No.: 11/730533   Filing Date: 02/Apr/2007

Abstract:

Composition with at least one polymerizable binder and a polymerization initiator, which contains at least one acylgermane according to general Formula (I), in which R<0 >is a substituted or unsubstituted C1-18-alkyl radical or an acyl group

R<1 >and R<2 >are H, an acyl group or have one of the meanings given for R<3>

R<3 >is a branched or linear C1-18-alkyl radical which can be unsubstituted or substituted one or more times by -O-, -NH-, -NR-, -S- or interrupted by other groups, trimethylsilyl, hal-(CH3)2Si-[OSi(CH3)2]r<->, (CH3)3Si-[OSi(CH3)2]r-, -COOH, -COO-R<10>, -CO-NR<11>R<12>, -CO-vinyl, -CO-phenyl, phenyl-C1-4-alkyl, phenyl, naphthyl or biphenyl, C5-12 cycloalkyl, a 5 or 6-membered O, S or N-containing heterocyclic ring, halogen, OH, an aromatic C6-30 radical which can be substituted or unsubstituted and/or interrupted by O, S or -NR-, or a branched, cyclic or linear C1-20 alkyl, -alkenyl, -alkoxy or -alkenoxy radical

m is 1, 2 or 3

n is 0 or 1 and p is 0 or 1

and the use of acyl germanes of Formula (I) for example as initiator for radical polymerization.

Priority: EP20060121333 Applic. Date: 2006-09-27

Inventor: MOSZNER NORBERT [DE]; SALZ ULRICH [DE]; FISCHER URS KARL [CH]; LISKA ROBERT [AT]; GRUBER HEINRICH [AT]; GANSTER BEATE [AT]


Application No.: US20080076848A1  Published: 27/Mar/2008

Title: Low stress flowable compositions

Applicant/Assignee:

Application No.: 11/811264   Filing Date: 08/Jun/2007

Abstract:

A photopolymerizable and photocleavable (P&P) resin monomer is derived from a reactive photoresponsible moiety via various linkages to form photopolymerizable monomers and/or oligomers.

Priority: US20060812541P Applic. Date: 2006-06-09

Inventor: JIN XIAOMING [US]; HAMMESFAHR PAUL D [US]


Application No.: US20080078787A1  Published: 03/Apr/2008

Title: CARABINER BOTTLE CLOSURE

Applicant/Assignee:

Application No.: 11/538047   Filing Date: 02/Oct/2006

Abstract:

A closure for removably sealing a container and for attaching to external articles having an external hooking device. The closure includes a container cap configured to removably engage the container and having a strip engaging portion formed proximate an end of the cap. The closure includes an attachment member that has a resilient hooking strip extending from the lid to define a hooking aperture therebetween. The attachment member has a cap engaging portion formed adjacent an end thereof and releasably engaged to the strip engaging portion. The engaging portions are configured such that the cap engaging portion is releasable from engagement by applying disengaging force upon any portion of the hooking strip.

Priority:

Inventor: YELLAND WILLIAM [CA]


Application No.: US20080081313A1  Published: 03/Apr/2008

Title: Dental filing tool

Applicant/Assignee:

Application No.: 11/982117   Filing Date: 01/Nov/2007

Abstract:

A dental filing tool and method for use includes providing a unitary injection-molded handle with integral finger pads, indicia markings, and an abrasive filing strip embedded into the handle vertical arms

inserting the tool between teeth to cut and file restorations

and, disposing after use. A method for making a dental filing tool is provided, including the steps: selecting a strip

providing the strip with abrasive means

providing the strip with mounting holes

providing an injection mold with a horizontal and first and second vertical arm channels, each of the vertical arm channels having flattened opposing outer edges to form integral finger pads

and, first and second mounting pins spaced distally to hold the strip in tension

mounting the strip onto the pins within the mold

injecting plastic by injection molding means to form the dental filing tool

cooling the dental filing tool until resilient

and, removing the filing tool.

Priority: US2004-945033 Applic. Date: 2004-09-21

Inventor: KIM DANIEL S [US]


Application No.: US20080081791A1  Published: 03/Apr/2008

Title: Methods of using combinations of siRNAs for treating a disease or a disorder, and for enhancing siRNA efficacy in RNAi

Applicant/Assignee:

Application No.: 11/481879   Filing Date: 06/Jul/2006

Abstract:

The present invention provides methods for treating diseases or disorders, and methods for enhancing siRNA efficacy in RNAi, including administering to a subject or a biological system one or more siRNAs capable of down regulating the expression of one or more target genes and one or more siRNAs capable of down regulating the expression of one or more negative regulators of RNAi. The present invention also provides compositions including one or more siRNAs, or precursors thereof, capable of down regulating the expression of one or more target genes and comprising one or more siRNAs, or precursors thereof, capable of down regulating the expression of one or more negative regulators of RNAi.

Priority:

Inventor: HUANG WEIDA [CN]; HONG JIE [CN]; QIAN ZHIKANG [CN]


Application No.: US20080081849A1  Published: 03/Apr/2008

Title: DENTAL RESTORATIVE MATERIAL COMPOSITION

Applicant/Assignee: GC CORPORATION

Application No.: 11/858403   Filing Date: 20/Sep/2007

Abstract:

To provide a dental restorative material composition using an organic-inorganic composite filler having excellent surface smoothness like a natural tooth, low polymerization shrinkage, excellent X-ray contrast imaging property, similar transparency to that of a natural tooth, and no variation of transparency before and after the composition is hardened, the dental restorative material composition includes (a) a (meth)acrylate monomer, (b) an organic-inorganic composite filler having an average particle diameter of 5 to 50 mum which is made by mixing a (meth)acrylate monomer and a fine particle filler having an average primary particle diameter of 0.005 to 0.3 mum and having X-ray impermeability, (c) a fine particle filler having an average primary particle diameter of 0.005 to 0.04 mum, and (d) a photopolymerization initiator.

Priority: JP20060265998 Applic. Date: 2006-09-28

Inventor: FUSEJIMA FUTOSHI [JP]; JIMBO NAOKO [JP]; KAGA SHINJI [JP]


Application No.: US20080081852A1  Published: 03/Apr/2008

Title: MOUTH GUARD COMPOSITION

Applicant/Assignee: GC CORPORATION

Application No.: 11/859341   Filing Date: 21/Sep/2007

Abstract:

A mouth guard composition comprises 39 to 98% by weight of styrene block copolymer

1 to 60% by weight of one or more kinds of thermoplastic resins selected from the group consisting of aliphatic cyclic saturated hydrocarbon resin, terpene resin, aliphatic petroleum resin and ester gum

and 0.1 to 40% by weight of one or more kinds of waxes selected from the group consisting of mineral wax, synthetic wax, plant wax, and animal wax, said composition further comprising 0.1 to 20% by weight of polyolefin resin, thereby providing the mouth guard composition which is not largely distorted when extremely strong impact force is applied thereto during the use of the mouth guard and can protect teeth and jaws, and little wearing is caused when repetitive force is applied.

Priority: JP20060269399 Applic. Date: 2006-09-29

Inventor: KAMOHARA HIROSHI [JP]; FUKUSHIMA SHOUICHI [JP]; TSUNOOKA MIYUKI [JP]


Application No.: US20080083074A1  Published: 10/Apr/2008

Title: Mouth cleaning device

Applicant/Assignee: MATSUSHITA ELECTRIC WORKS, LTD

Application No.: 11/905640   Filing Date: 03/Oct/2007

Abstract:

A mouth cleaning device includes: a head portion provided with bristles and an electrode

and a handle portion provided with an electrode. In the mouth cleaning device, when an electric circuit is formed from one electrode to the other electrode via a human body by application of a voltage to the electrodes, a pulse current having a frequency of about 4000 Hz to about 15000 Hz flows therein.

Priority: JP20060275682 Applic. Date: 2006-10-06

Inventor: TANIGUCHI SHINICHI [JP]; KISHIMOTO SUEHISA [JP]; KUNITA TOMOHIRO [JP]; SHIMIZU HIROAKI [JP]


Application No.: US20080085248A1  Published: 10/Apr/2008

Title: Controlled Long Acting Release Pharmaceutical Preparation For Use In The Oral Cavity

Applicant/Assignee:

Application No.: 11/794168   Filing Date: 28/Dec/2005

Abstract:

The present invention relates to a controlled long acting release pharmaceutical preparation for use in the oral cavity either for the treatment of diseases of the oral cavity or

for releasing said pharmaceutical preparation into said oral cavity. Said pharmaceutical preparation comprises at least a therapeutic agent, a binder and a lubricant (hereinafter "the preparation" or "the pharmaceutical preparation").

Priority: IL20050166114 Applic. Date: 2005-01-03; WO2005IL01385 Applic. Date: 2005-12-28

Inventor: SELA YORAM [IL]


Application No.: US20080085331A1  Published: 10/Apr/2008

Title: Composition and method for raising blood glucose level

Applicant/Assignee:

Application No.: 11/544530   Filing Date: 06/Oct/2006

Abstract:

Composition, non-aerosol dispenser containing the composition, and method of raising the blood glucose level of an individual comprising administering an effective amount of the composition to an oral mucosa of the individual. The composition comprises: a. an effective amount of glucose, b. an effective amount of at least one absorption enhancer chosen from lecithin, hyaluronic acid, glycolic acid, lactic acid, chamomile extract, cucumber extract, oleic acid, linoleic acid, linolenic acid, monoolein, monooleates, monolaurates, borage oil, evening primrose oil, menthol, trihydroxy oxo cholanyl glycine, glycerin, polyglycerin, lysine, polylysine, triolein, polyoxyethylene ethers, polidocanol alkyl ethers, chenodeoxycholate, deoxycholate, alkali metal salicylate, pharmaceutically acceptable edetate, and pharmaceutically acceptable salts and analogues thereof, and c. an effective amount of a pharmaceutically acceptable carrier, wherein the composition is free of any active pharmaceutical agents.

Priority:

Inventor: GLUSKIN ANNA E [CA]; QAZI MUHAMMAD WASEEM T [CA]


Application No.: US20080085412A1  Published: 10/Apr/2008

Title: SILICA-COATED METAL OXIDE SOLS HAVING VARIABLE METAL OXIDE TO SILICA RATIO

Applicant/Assignee:

Application No.: 11/538477   Filing Date: 04/Oct/2006

Abstract:

This invention provides metal-rich siliceous compositions and methods of preparing such compositions. The compositions have comprehensibly variable and controllable metal oxide to silica ratios, surface morphology, porosity, and surface area. The method includes preparing a silicic acid, a metal oxide dispersion, and a basic heel solution. The silicic acid and metal oxide dispersion are mixed to create a blend and the blend is controllably added to the basic heel solution to form a siliceous material including colloidal silica-coated metal oxide particles. Factors such as type of silicic acid, concentration and type of metal oxide, and reaction conditions determine properties, including surface morphology and porosity, of the siliceous material

Priority:

Inventor: ORTIZ C YOLANDA [US]


Application No.: US20080085458A1  Published: 10/Apr/2008

Title: Oxime Derivatives And Use Thereof As Latent Acids

Applicant/Assignee: CIBA SPECIALTY CHEMICALS CORPORATION

Application No.: 11/632687   Filing Date: 11/Jul/2005

Abstract:

The invention pertain to novel photoacid generator compounds of the formula I, II or III wherein R1 is for example C1-C18alkylsulfonyl or phenylsulfonyl, phenyl-C1-C3alkylsulfonyl, naphthylsulfonyl, anthracylsulfonyl or phenanthrylsulfonyl, all optionally substituted, or R1 is a group X1, X2 and X3 independently of each other are O or S

R'1, is e.g. phenylenedisulfonyl, naphthylenedisulfonyl, diphenylenedisulfonyl, or oxydiphenylenedisulfonyl, all optionally substituted

R2 is halogen or C1-C10haloalkyl

X is halogen

Ar1 is for example biphenylyl or fluorenyl, or is substituted naphthyl

Ar'1 is heteroarylene, optionally substituted

R8, R9, R10 and R11 for example are C1-C6alkyl which is unsubstituted or substituted by halogen

or R8, R9 and R10 are phenyl which is unsubstituted or substituted by C1-C4alkyl or halogen

or R10 and R11 together are 1,2-phenylene or C2-C6alkylene which is unsubstituted or substituted by C1-C4alkyl or halogen.

Priority: EP20040103453 Applic. Date: 2004-07-20; WO2005EP53296 Applic. Date: 2005-07-11

Inventor: YAMATO HITOSHI [JP]; ASAKURA TOSHIKAGE [JP]; HINTERMANN TOBIAS [CH]


Application No.: US20080085493A1  Published: 10/Apr/2008

Title: Methods for making provisional and long-term dental crowns and bridges

Applicant/Assignee:

Application No.: 11/805672   Filing Date: 24/May/2007

Abstract:

The invention provides methods of making provisional and long-term dental restorations, particularly dental veneers, crowns and bridges. In one embodiment, the restoration can be fabricated indirectly by a dental laboratory. In another version, a dental practitioner can make the restoration chairside for a patient in a dental office. A polymerizable dental composite material, which is dimensionally shape-stable in its uncured state, is used to make the restoration. The material includes a polymerizable acrylic compound, polymerization initiator system capable of being activated by light or heat, and a filler material. The resulting dental restoration has good aesthetics, mechanical strength, and margins and contacts.

Priority: US20060848117P Applic. Date: 2006-09-29

Inventor: SUN BENJAMIN J [US]; YOUNG ANDREW M [US]; LICHKUS ANDREW M [US]


Application No.: US20080085494A1  Published: 10/Apr/2008

Title: Dental Compositions Containing Oxirane Monomers

Applicant/Assignee:

Application No.: 11/571943   Filing Date: 13/Jul/2005

Abstract:

Epoxy-functional ether monomers (i.e., oxirane monomers) for use in oxirane-based dental compositions.

Priority: US20040587977P Applic. Date: 2004-07-14; WO2005US24822 Applic. Date: 2005-07-13

Inventor: MADER ROGER M [US]; JACOBS DWIGHT W [US]; ECKERT ADRIAN S [DE]


Application No.: US20080085533A1  Published: 10/Apr/2008

Title: Method and apparatus for non -invasive rinse diagnosis and monitoring of periodontal diseases

Applicant/Assignee:

Application No.: 11/543202   Filing Date: 05/Oct/2006

Abstract:

An assay test kit is used in a mouth rinse sample collection procedure involving collecting a mouth rinse sample from a patient. A neutrophil reactant diagnostic reagent is delivered to the rinse sample immediately after collection. Diagnostic reagents containing diammonium salts that are reactive with neutrophil enzymes are added to the sample to produce visually discernable colour change in the solution after a selected period of time. Most preferably, the reagents are selected to produce a colour change after a period of time. The reaction is then measured by comparing the resulting sample colour change by eye or mechanically to a standardized colour chart/swatch that correlates with predetermined neutrophil concentrations and/or periodontal disease levels.

Priority:

Inventor: GLOGAUER MICHAEL [CA]


Application No.: US20080085823A1  Published: 10/Apr/2008

Title: Method for Making a Bag

Applicant/Assignee:

Application No.: 11/793728   Filing Date: 13/Dec/2005

Abstract:

A method for making bags from flexible plastic film comprises the steps of feeding a sheet of plastic film

making at least one indented pleated portion in the film and, in particular, a first and a second indented pleated portion ( 916, 918 ), and e forming the film into a tubular shape. According to the method of the invention, means are provided for sealing the respective end ( 916', 918' ) of the pleated portion, said means being in the form of a respective sealing band ( 942 ).

Priority: IT2004MI02491 Applic. Date: 2004-12-23; IT2005BO00265 Applic. Date: 2005-04-21; WO2005IB03954 Applic. Date: 2005-12-13

Inventor: REGGI MARCO [IT]


Application No.: US20080085828A1  Published: 10/Apr/2008

Title: Coloring of ceramics by atmospheric control

Applicant/Assignee: PENTRON CERAMICS, INC

Application No.: 11/889945   Filing Date: 17/Aug/2007

Abstract:

Methods of forming a colored ceramic body or dental article are described that include: (a) forming a body from a ceramic-containing powder

(b) shaping the body into a desired shape

and (c) firing the shaped body in an atmosphere comprising at least one coloring agent. Methods of forming a fully dense ceramic body that lacks discoloration, are also described which include: (a) forming a body from a ceramic-containing powder

(b) shaping the body into a desired shape

(c) placing the shaped body in a firing atmosphere containing at least one impurity that promote discoloration of the ceramic body

(d) placing the ceramic body in proximity to an atmosphere powder

and (e) firing the shaped body in proximity to an atmosphere powder

wherein the atmosphere powder acts as at least one of a barrier and a getter for the at least one impurity.

Priority: US20060838375P Applic. Date: 2006-08-18

Inventor: KHAN AJMAL [US]; BRODKIN DMITRI G [US]


Application No.: US20080085901A1  Published: 10/Apr/2008

Title: Heteroaryl Substituted Quinolin-4-Ylamine Analogues

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 11/795269   Filing Date: 13/Jan/2006

Abstract:

Heteroaryl substituted quinolin-4-ylamine analogues of Formula I are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20050644503P Applic. Date: 2005-01-14; WO2006US01345 Applic. Date: 2006-01-13

Inventor: CALDWELL TIMOTHY M [US]; CHENARD BERTRAND L [US]; HODGETTS KEVIN J [US]


Application No.: US20080086189A1  Published: 10/Apr/2008

Title: Mouth cleaning device

Applicant/Assignee: MATSUSHITA ELECTRIC WORKS, LTD

Application No.: 11/905641   Filing Date: 03/Oct/2007

Abstract:

A mouth cleaning device includes a head portion provided with bristles and an electrode

and a grip portion provided with an electrode. Further, the mouth cleaning device includes a boosting circuit for boosting an output voltage of a battery serving as a power source and applying the boosted voltage to the electrodes of the head portion and the grip portion

and a current limit circuit for limiting a current flowing from one electrode to the other via a human body.

Priority: JP20060275681 Applic. Date: 2006-10-06

Inventor: TANIGUCHI SHINICHI [JP]; KISHIMOTO SUEHISA [JP]; KUNITA TOMOHIRO [JP]; SHIMIZU HIROAKI [JP]; TAKAHASHI ATSUSHI [JP]; NAGAYAMA MASAYOSHI [JP]; HANATO YUMI [JP]; SANEMATSU WATARU [JP]; MASUDA YUKIHIRO [JP]


Application No.: US20080086835A1  Published: 17/Apr/2008

Title: Vacuum cleaning device

Applicant/Assignee: ALFRED KAERCHER GMBH & CO. KG

Application No.: 11/973874   Filing Date: 09/Oct/2007

Abstract:

The invention relates to a vacuum cleaning device comprising a dirt collection container which has a suction inlet and is in flow connection with at least one suction unit via at least one filter and at least one suction line, and comprising at least one external air inlet which opens into the suction line downstream of the at least one filter and is adapted to be closed by means of at least one closing valve, the closing valve having a movable valve body which, in a closed position, bears against at least one valve seat so as to form one or more sealing lines, the at least one sealing line delimiting an area which, in the closed position of the closing valve, is acted upon by a differential pressure. In order to develop the vacuum cleaning device in such a way that the at least one closing valve is of structurally simple design and the at least one filter can be completely cleaned within a short period of time, the invention proposes that the square of the total length of all sealing lines is at least 25 times the total size of all areas which are delimited by the sealing lines and acted upon by a differential pressure.

Priority: DE200510017568 Applic. Date: 2005-04-11; WO2006EP00672 Applic. Date: 2006-01-26

Inventor: STEWEN CHRISTIAN [DE]; HAEUSSERMANN ULI [DE]


Application No.: US20080087279A1  Published: 17/Apr/2008

Title: Metered dose inhaler

Applicant/Assignee:

Application No.: 11/546224   Filing Date: 11/Oct/2006

Abstract:

There is disclosed a metered dose inhaler for administering medication. In an embodiment, the metered dose inhaler includes a housing, a medication canister, a mouth-piece, an extension forming a chamber within the housing, and a one-way valve. In one embodiment, the metered dose inhaler includes a flange disposed on the mouth-piece. In another embodiment, the metered dose inhaler includes a peripheral edge configured to reduce spray away from the mouth-piece. In an embodiment, the metered dose inhaler includes a telescoping articulation between first and second ends of the housing. In another embodiment, the metered dose inhaler includes a telescoping extension. Other embodiments are also disclosed.

Priority:

Inventor: TIECK CATHARINE LAUREEN JOHNSO [US]; JOHNSON KENNETH WILLIAM [US]


Application No.: US20080087565A1  Published: 17/Apr/2008

Title: Patient Check System

Applicant/Assignee: SAGE PRODUCTS, INC

Application No.: 11/928816   Filing Date: 30/Oct/2007

Abstract:

A system for assisting in communication of the state of a patient's condition is disclosed. In an embodiment, a plastic container of washcloths includes two labels. The first label is mounted on the container and occludes an entry into the container. The second label also is mounted on the container via attachment to the first label. The second label includes a template that is mounted face down. In operation, the second label may be removed and observations regarding the patient's skin condition that are made during use of the washcloth can be marked on the template provided on the second label. The second label then may be communicated from one care provider to another care provider.

Priority: US2005-170995 Applic. Date: 2005-06-29

Inventor: CHAPPUIS RON [US]; HANIFL PAUL [US]; LAYER JAMES [US]


Application No.: US20080089978A1  Published: 17/Apr/2008

Title: LACTEAL COATED PIZZAS

Applicant/Assignee: BODY STRUCTURES, INC

Application No.: 11/309851   Filing Date: 13/Oct/2006

Abstract:

From dietary health to product diversity, Lacteal Coated Pizzas outperform the venerable four-hundred year old ethnic (Italian) pizzas. Lacteal Coated Pizzas are comprised of soft leaven dough/sourdough that is topped with a delicious, nutritious Lacteal Batter, and a conventional topping. The present invention's Lacteal Batters are innovative, heat-stable, hydrocolloidal-proteineous mixtures that possess unique performance-enhancing, rheological properties.

Priority:

Inventor: GRIGG LOUISE J [US]; JONSAN JOHN [US]


Application No.: US20080090210A1  Published: 17/Apr/2008

Title: Arrangement For Forming A Hole In A Jaw Bone, And Implant For Application In Said Hole

Applicant/Assignee:

Application No.: 11/587876   Filing Date: 26/Sep/2007

Abstract:

An arrangement for application or anchoring of an implant ( 17 ) in a jaw bone ( 8 ) by means of a hole formed in the jaw bone comprises a manually driven or machine-driven part which cooperates with the hole wall and which is designed to work with a hole wall cleaning function in order to form a surgically clean cut in the jaw bone. The implant can be arranged to be applied in the hole formed, and the implant is provided with one or more threads or thread parts which, when the implant is in the applied position, can be located opposite the cortical area or areas in the jaw bone. The implant is threads at the part or parts located opposite the spongy area or areas ( 11 ) of the jaw bone. By means of the invention, a surgically clean cut is obtained which, together with the design of the implant, contributes to accelerated osseointegration.

Priority: SE20040001096 Applic. Date: 2004-04-29; WO2005SE00294 Applic. Date: 2005-03-02

Inventor: BRAJNOVIC IZIDOR [SE]


Application No.: US20080090774A1  Published: 17/Apr/2008

Title: Nucleoside compounds and their use for treating cancer and diseases associated with somatic mutations

Applicant/Assignee: PTC THERAPEUTICS, INC

Application No.: 11/906665   Filing Date: 02/Oct/2007

Abstract:

The invention encompasses nucleoside compounds, compositions comprising the compounds and methods for treating or preventing diseases associated with nonsense mutations of mRNA by administering these compounds or compositions.

Priority: US2003-625059 Applic. Date: 2003-07-22; US20020398334P Applic. Date: 2002-07-24

Inventor: WILDE RICHARD G [US]; KENNEDY PAUL D [US]; ALMSTEAD NEIL G [US]; WELCH ELLEN M [US]; TAKASUGI JAMES J [US]; FRIESEN WESTLEY J [US]


Application No.: US20080090823A1  Published: 17/Apr/2008

Title: THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS

Applicant/Assignee: SCHERING CORP PHARMACOPEIA DRUG DISCOVERY, INC

Application No.: 11/861870   Filing Date: 26/Sep/2007

Abstract:

Disclosed are novel compounds of the formula: and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and ischemia reperfusion injury, pain (e.g., acute pain, acute and chronic inflammatory pain, and neuropathic pain) using a compound of formula IA.

Priority: US2004-013753 Applic. Date: 2004-12-16; US20030531311P Applic. Date: 2003-12-19; US20030531713P Applic. Date: 2003-12-22

Inventor: BIJU PURAKKATTLE J [US]; TAVERAS ARTHUR G [US]; MERRITT J R [US]; BALDWIN JOHN J [US]; YU YOUNONG [US]; ZHENG JUNYING [US]; CHAO JIANHUA [US]; AKI CYNTHIA J [US]; FINE JAY [US]; LUNDELL DANIEL [US]; PRIESTLEY TONY [US]; REGGIANI ANGELO [IT]


Application No.: US20080090841A1  Published: 17/Apr/2008

Title: METHODS OF ENHANCING MUCOSAL HYDRATION AND MUCOSAL CLEARANCE BY TREATMENT WITH SODIUM CHANNEL BLOCKERS AND OSMOLYTES

Applicant/Assignee: PARION SCIENCES, INC

Application No.: 11/851803   Filing Date: 07/Sep/2007

Abstract:

The present invention relates to methods and compositions for treating diseases ameliorated by increased mucociliary clearance and mucosal hydration by administering an effective amount of a sodium channel blocker as defined herein and an osmolyte to a subject to a subject in need of increased mucociliary clearance and mucosal hydration.

Priority: US20060845171P Applic. Date: 2006-09-18; US20060842669P Applic. Date: 2006-09-07

Inventor: JOHNSON MICHAEL R [US]; BOUCHER RICHARD C [US]; HIRSH ANDREW J [US]


Application No.: US20080090845A1  Published: 17/Apr/2008

Title: Haloalkyl-substituted pyrimidinone derivatives

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 11/895266   Filing Date: 22/Aug/2007

Abstract:

Haloalkyl-substituted pyrimidinone derivatives are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20060823261P Applic. Date: 2006-08-23

Inventor: BLUM CHARLES A [US]; ZHENG XIAOZHANG [US]; MARTINEZ ISAMIR [US]; CHENARD BERTRAND L [US]


Application No.: US20080090979A1  Published: 17/Apr/2008

Title: METHYLENE BLUE

Applicant/Assignee: STRAUMANN HOLDING AG

Application No.: 11/872234   Filing Date: 15/Oct/2007

Abstract:

Composition comprising a polymerizable compound with at least one conjugated unsaturated group and methylene blue to prevent premature polymerization of the polymerizable compound. The methylene blue is present in a concentration of 10 to 5000 ppm.

Priority: EP20050020181 Applic. Date: 2005-09-16; EP20040014072 Applic. Date: 2004-06-16; US2006-521971 Applic. Date: 2006-09-15; US2006-629567 Applic. Date: 2006-12-14; WO2005EP04977 Applic. Date: 2005-05-09

Inventor: MOLENBERG AALDERT [CH]


Application No.: US20080091233A1  Published: 17/Apr/2008

Title: Compositions and methods for affecting movement of contaminants, bodily fluids or other entities, and/or affecting other physiological conditions

Applicant/Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY

Application No.: 11/796132   Filing Date: 25/Apr/2007

Abstract:

Compositions which self-assemble under physiological conditions are formulated for application to wounds. The formulations include a pharmaceutically acceptable carrier or are provided as part of a medical device or coating. The formulations may also include other therapeutic, prophylactic or diagnostic agents. The formulation can be administered as appropriate for treatment of one or more disorders or conditions. For example, the formulation may be applied to repair an injury or during surgery of the lung, eye or dura, or following an epidural or spinal tap, to stop leakage of blood, interstitial fluid, or cerebrospinal fluid. The formulation may be administered to a burn or ulcer. The formulation may be dispersed in a suture or adhesive for administration at the time of or as released following suturing or gluing of a wound, thereby limiting bleeding, loss of tissue fluids, or other fluids such as those produced by parenchymal tissues such as the liver, pancreas, and gastrointestinal tract. The formulation may be applied to any site of bleeding, in a bandage, gauze, sponge, or other material, for immediate control of bleeding, or released later to control bleeding if the initial treatment such as suturing or pressure is insufficient. In one embodiment, the formulation is provided as a dry or lyophilized powder. In another embodiment, the material is provided in water. In another embodiment, the material is provided in combination with an oil and forms a laminate. In another embodiment, the formulation is provided as a coating on a device, for example a stent or a catheter. The material is also useful to isolate tissue, for preservation of tissue for subsequent transplantation or reattachment, and as a bulking, stabilizing or hydrating agent.

Priority: US20060745601P Applic. Date: 2006-04-25

Inventor: ELLIS-BEHNKE RUTLEDGE [US]; LIANG YU-XIANG [CN]; SCHNEIDER GERALD E [US]; SO KWOK-FAI [CN]; TAY DAVID [CN]


Application No.: US20080092917A1  Published: 24/Apr/2008

Title: MOTORIZED FLOSSER AND METHOD OF USE

Applicant/Assignee: THE WILLIAM GETGEY COMPANY, INC

Application No.: 11/961128   Filing Date: 20/Dec/2007

Abstract:

A motorized flosser comprising an elongated body and a flossing head secured to an end portion of the elongated body. The flossing head oscillates in an arcuate manner. A battery powered motor drives a drive mechanism which reciprocates an output drive shaft, which drive shaft is in turn connected through a flexible drive rod to a drive disc. The drive disc oscillates in a rotary arcuate motion to impart either pure rotary arcuate oscillatory motion or a combined rotary arcuate motion and translatory motion to flossing material carried by a yoke of the flossing head. The flossing head may incorporate a toothpaste holder mounted upon the flossing head or toothbrush bristles mounted upon tines of the yoke of the flossing head.

Priority: US2005-224896 Applic. Date: 2005-09-13

Inventor: GETGEY WILLIAM F [US]; DYSON LEWIS R [US]; ANDRY CARL R [US]; FURNISH GREGORY R [US]


Application No.: US20080093064A1  Published: 24/Apr/2008

Title: CORROSION-RESISTANT BIMETALLIC TUBE AND ITS USE IN TUBE BUNDLE EQUIPMENT

Applicant/Assignee: SNAMPROGETTI S.P.A

Application No.: 11/761735   Filing Date: 12/Jun/2007

Abstract:

A bimetallic tube consisting of at least one tubular element in a first metal resistant to the corrosive and/or erosive action of a process fluid with which it is put in contact, having at least one end, or an area close to an end, externally coated with a layer of a second metal, different from the first and more suitable, with respect to this, for being seal-welded to a support. Tube bundle equipment to be used for thermal exchange operations at high temperatures and pressures, under conditions of high aggressiveness of the process fluids, wherein the tube bundle comprises at least one tube having the above characteristics. Said equipment is particularly used as a heat exchanger and decomposer, for example as a stripper, in the cycle of urea synthesis processes where there are conditions of high pressure, high temperatures, high aggressiveness of the process fluids, and in which the tube bundle consists of at least one tube having the above characteristics.

Priority: IT2006MI01223 Applic. Date: 2006-06-26

Inventor: GIANAZZA ALESSANDRO [IT]; MAIRANO LUCA [IT]; MERELLI GIUSEPPE [IT]; SANFILIPPO DOMENICO [IT]


Application No.: US20080095719A1  Published: 24/Apr/2008

Title: Blackberry Extract

Applicant/Assignee: SYMRISE GMBH & CO. KG

Application No.: 11/629753   Filing Date: 16/Jun/2005

Abstract:

The invention concerns a blackberry leaf extract and its uses, in particular to slow down skin ageing, to treat the oral and pharyngeal cavity, and there in particular to prevent and slow down periodontitis and the excessive degradation of the periodontal connective tissue as well as damage to the teeth caused by matrix metalloproteinases

Priority: US20040581307P Applic. Date: 2004-06-18; US20050654380P Applic. Date: 2005-02-18; WO2005EP52793 Applic. Date: 2005-06-16

Inventor: HERRMANN MARTINA [DE]; JOPPE HOLGER [DE]; FRANKE HELGE [DE]; VIELHABER GABRIELE [DE]


Application No.: US20080095811A1  Published: 24/Apr/2008

Title: METHODS OF BLEACHING TEETH USING ADHESIVE DENTAL BLEACHING COMPOSITIONS CONTAINING POLYVINYLPYRROLIDONE

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/924014   Filing Date: 25/Oct/2007

Abstract:

A dental bleaching composition comprises a dental bleaching agent and a polyvinylpyrrolidone thickening agent. The bleaching composition may include water, flavoring agents, a basic substance and desensitizing agents, as desired. Polyvinylpyrrolidone avoids acid etching and chelation of teeth that were problematic in bleaches using carbomer as a thickener. A delivery system for delivering the bleaching composition comprises the aforementioned dental bleaching composition in combination with a moisture-resistant barrier layer such as a dental tray or a flexible strip of material.

Priority: US2004-870293 Applic. Date: 2004-06-17; US2003-715003 Applic. Date: 2003-11-17; US2002-288239 Applic. Date: 2002-11-05; US2001-770489 Applic. Date: 2001-01-27

Inventor: CHEN TIANMING [CN]


Application No.: US20080095819A1  Published: 24/Apr/2008

Title: Composition and Methods for Promoting Wound Healing and tissue Regeneration

Applicant/Assignee: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT CHARLESTON

Application No.: 11/721529   Filing Date: 20/Dec/2005

Abstract:

Provided herein are compositions and methods for use in promoting wound healing and tissue regeneration following tissue injury in a subject.

Priority: US20040638366P Applic. Date: 2004-12-21; US20050671796P Applic. Date: 2005-04-15; WO2005US46442 Applic. Date: 2005-12-20

Inventor: GOURDIE ROBERT [US]; GHATNEKAR GAUTAM [US]; JOURDAN JANE [US]


Application No.: US20080095849A1  Published: 24/Apr/2008

Title: Peptide sustained release compositions and uses thereof

Applicant/Assignee: AMGEN INC

Application No.: 11/411464   Filing Date: 25/Apr/2006

Abstract:

Sustained delivery compositions that modulate the release of incorporated prophylactic, therapeutic, and/or diagnostic agents, and methods of preparation and use thereof, are disclosed. In particular embodiments, the compositions include a polymeric matrix

a prophylactic, therapeutic, and/or diagnostic agent dispersed and/or dissolved within the polymeric matrix

and a carbohydrate component that is separately dispersed within the polymeric matrix. The carbohydrate component modulates the release of the incorporated agent from the polymeric matrix. The compositions can be prepared by dissolving a biocompatible polymer in a solvent to form a polymer solution, and separately dispersing a carbohydrate and a prophylactic, therapeutic, and/or diagnostic agent within the polymer solution. The polymer solution is then solidified to form a polymeric matrix, wherein a significant amount of the carbohydrates is dispersed in the polymeric matrix separately from the incorporated agent. In particular embodiments, the compositions include a polymeric matrix and a B1 peptide antagonist dispersed within the polymeric matrix.

Priority: US20050674872P Applic. Date: 2005-04-25

Inventor: WU CINDY W [US]; BURKE PAUL [US]; GOLDENBERG MERRILL S [US]; SHAN DAXIAN [US]


Application No.: US20080096115A1  Published: 24/Apr/2008

Title: Oxime Ester Photoinitiators

Applicant/Assignee: CIBA SPECIALTY CHEMICALS CORP

Application No.: 11/660346   Filing Date: 08/Aug/2005

Abstract:

Compounds of the formula (I), wherein R1, R2 and R10 independently of one another are C1-C20alkyl, phenyl, C1-C12alkylphenyl or phenyl-C1-C6alkyl

R3 and R4 independently of one another are hydrogen, C1-C20alkyl, NR6R7 or SR8, provided that at least one of R3 or R4 is NR6R7 or SR8

R5 is hydrogen or C1-C20alkyl

R6 and R7 independently of one another are C1-C20alkyl, or R6 and R7 together with the N-atom to which they are attached form a 5 or 6 membered ring, which optionally is interrupted by O, S or NR9 and which optionally additionally is substituted by one or more C1-C4alkyl

R8 is phenyl, biphenylyl, naphthyl, anthryl or phenanthryl, all of which optionally are substituted by one or more C1-C4alkyl

and R9 is hydrogen, C1-C20alkyl, C2-C4hydroxyalkyl or phenyl

exhibit an unexpectedly good performance in photopolymerization reactions.

Priority: EP20040103962 Applic. Date: 2004-08-18; WO2005EP53894 Applic. Date: 2005-08-08

Inventor: TANABE JUNICHI [JP]; KUNIMOTO KAZUHIKO [JP]; KURA HISATOSHI [JP]; OKA HIDETAKA [JP]; OHWA MASAKI [JP]


Application No.: US20080096150A1  Published: 24/Apr/2008

Title: DENTAL ARTICLES, METHODS, AND KITS INCLUDING A COMPRESSIBLE MATERIAL

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/551823   Filing Date: 23/Oct/2006

Abstract:

The present invention provides dental articles, kits, and methods including a compressible material. The compressible material optionally includes a hardenable dental composition (e.g., an adhesive or primer) that can be useful for bonding the dental article (e.g., an orthodontic appliance) to a tooth structure. Removal of excess hardenable and/or hardened dental composition, if desired, can be facilitated for embodiments in which the hardenable dental composition is an unfilled or lightly filled composition.

Priority:

Inventor: CINADER DAVID K [US]


Application No.: US20080096161A1  Published: 24/Apr/2008

Title: Pneumatic dental care device

Applicant/Assignee:

Application No.: 11/520334   Filing Date: 13/Sep/2006

Abstract:

A pneumatic dental care device for in-home use that is particularly suited for cleaning and providing prophylaxis of teeth, gingiva, and other oral tissue wherein pressurized air is directed into a user's oral cavity to clean teeth, remove oral debris and to both stimulate and massage gum line tissue. The compressed air, by means of a length of flexible tube, is delivered from a pressurized air source to a hand piece having both a nozzle tip and only one hand piece conduit. A control button disposed on the hand piece operably opens and closes a valve located within the hand piece, thereby allowing or stopping the outflow of compressed air from the nozzle tip of the hand piece. Additionally, a method of installing such a pneumatic dental care device for in-home use is disclosed.

Priority:

Inventor: CAIN JOAN CHINIQUY [US]; PETERS DENNIS EUGENE [US]


Application No.: US20080096784A1  Published: 24/Apr/2008

Title: Composition for Cleaning Dental Instruments and Process

Applicant/Assignee: VOCO GMBH

Application No.: 11/866884   Filing Date: 03/Oct/2007

Abstract:

A composition for cleaning dental instruments, comprising or consisting of: (a) one or more amino acids and/or salts thereof (aminocarboxylates) in a total amount of from 20 to 70 parts by weight, preferably 27.5 to 70 parts by weight, (b) one or more alpha-hydroxy acids and/or salts thereof in a total amount of from 15 to 45 parts by weight, (c) one or more alkali metal carbonates and/or bicarbonates in a total amount of from 0 to 50 parts by weight, (d) one or more surfactants in a total amount of from 0 to 5 parts by weight, (e) one or more tabletting auxiliaries in a total amount of from 0 to 10 parts by weight, (f) one or more corrosion inhibitors in a total amount of from 0 to 5 parts by weight, and (g) one or more other additives in a total amount of from 0 to 55 parts by weight, wherein components (a), (b), (c), (d), (e), (f) and (g)

are present in total in an amount of 100 parts by weight, and wherein the components are chosen such that the pH of a solution prepared by mixing the composition with 4,000 parts by weight of water is in the range of from 7.0 to 9.5.

Priority: EP20060125777 Applic. Date: 2006-12-11; CA20062570970 Applic. Date: 2006-12-11; WO2006EP62315 Applic. Date: 2006-05-15

Inventor: BARG ANDREE [DE]; PLAUMANN MANFRED T [DE]


Application No.: US20080096896A1  Published: 24/Apr/2008

Title: Cyclic Amide & Ester Pyrazinoylganidine Sodium Channel Blockers

Applicant/Assignee: PARION SCIENCES, INC

Application No.: 11/573693   Filing Date: 18/Aug/2005

Abstract:

The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.

Priority: US20040602312P Applic. Date: 2004-08-18; WO2005US29345 Applic. Date: 2005-08-18

Inventor: JOHNSON MICHAEL R [US]


Application No.: US20080096919A1  Published: 24/Apr/2008

Title: Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same

Applicant/Assignee: RENOVIS, INC

Application No.: 11/895293   Filing Date: 23/Aug/2007

Abstract:

Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

Priority: US2006-375692 Applic. Date: 2006-03-14; US20050661531P Applic. Date: 2005-03-14

Inventor: KELLY MICHAEL G [US]; KINCAID JOHN [US]; JANAGANI SATYANARAYANA [US]; DUNCTON MATTHEW [US]


Application No.: US20080098852A1  Published: 01/May/2008

Title: Material forming a dental coping in the prepartion of a dental restoration

Applicant/Assignee:

Application No.: 11/586081   Filing Date: 26/Oct/2006

Abstract:

A material composition for use in forming a porous metal structure and dental coping in the preparation of a dental restoration comprising a composite of metal particles in a matrix including low fusing temperature metal particles and at least between 35 to 85% medium fusing temperature metal particles by volume with the medium fusing temperature metal particles possessing a melting characteristic which during heat treatment of the material composition to form the porous metal structure results in partial melting of the medium fusing temperature metal particles to the extent of between about 4% to 50% by volume of the particle mass of each medium fusing temperature metal particle.

Priority:

Inventor: SHOHER ITZHAK [IL]; WHITEMAN AHARON [IL]


Application No.: US20080099100A1  Published: 01/May/2008

Title: Funnel Having Stabilizing Weight

Applicant/Assignee:

Application No.: 11/553295   Filing Date: 26/Oct/2006

Abstract:

A weight for supporting a funnel in an upstanding orientation, the weight comprising a periphery defining an internal void, the void receiving the neck of the funnel, and also having a filler housed within the periphery, the filler providing mass to the weight. Other embodiments include a funnel with a weight incorporated therein, and a funnel system comprising a funnel, a removable weight and indicator means operatively coupled with the funnel.

Priority:

Inventor: FERGUSON JOE [US]


Application No.: US20080099390A1  Published: 01/May/2008

Title: Low-cost magnetically aided apparatus for separating dental amalgam from waste water

Applicant/Assignee:

Application No.: 11/586802   Filing Date: 25/Oct/2006

Abstract:

A replaceable module for capturing amalgam and mercury from the waste water disposal system of a dental office, in which the waste water flows into a settling chamber, overflows from the settling chamber into a magnetically-assisted sluice, and then after being further cleaned by the sluice, flows on to a sewer connection.

Priority:

Inventor: PLATH DAVID C [US]


Application No.: US20080102043A1  Published: 01/May/2008

Title: ANTIMICROBIAL FLAVOR AND ORAL CARE COMPOSITON CONTAINING THE SAME

Applicant/Assignee: TAKASAGO INTERNATIONAL CORPORATION

Application No.: 11/947549   Filing Date: 29/Nov/2007

Abstract:

The present invention provides antimicrobial flavors and flavor compositions which are of high safety and little influential on intestinal bacteria, as well as oral care compositions and foods containing the same. The flavor is selected from dihydrofarnesol, isocamphylcyclohexanol, levosandol, bacdanol, Santalinol, methyl atrarate, 10-undecen-1-ol, 2-methyl undecanal, sandalol, dodecanal, brahmanol, neroridol, o-methoxycinnamic aldehyde, methyl sandeflor, 9-decen-1-ol, 3-dodecenal, etc.

Priority: JP20010062916 Applic. Date: 2001-03-07; US2003-424774 Applic. Date: 2003-04-29; US2002-090642 Applic. Date: 2002-03-06

Inventor: HANADA MINORU [JP]; ARAI HARUO [JP]


Application No.: US20080102090A1  Published: 01/May/2008

Title: Pharmaceutical Compositon Containing Botulinum Neurotoxin A2

Applicant/Assignee:

Application No.: 11/659449   Filing Date: 03/Aug/2005

Abstract:

A composition, medicament or use, comprising or consisting of botulinum toxin type A2 and a surfactant, having one or more or all of the characteristics selected from the group consisting of

(a) a much longer duration of action

(b) a much faster rate of onset of muscular paralysis

(c) a significantly greater intramuscular safety margin

(d) a selective action on inhibition of smooth muscle contraction

(e) a selective action on inhibition of pain-related (nociceptive) nerve cell function: Wherein each characteristic is determined comparative to the same characteristic effect of botulinum toxin type A1.

Priority: GB20040017367 Applic. Date: 2004-08-04; GB20040021288 Applic. Date: 2004-09-24; GB20040021290 Applic. Date: 2004-09-24; GB20040023950 Applic. Date: 2004-10-28; GB20040023953 Applic. Date: 2004-10-28; WO2005GB03057 Applic. Date: 2005-08-03

Inventor: PANJWANI NAVEED [GB]; WEBB PAUL [GB]; PICKETT ANDY [GB]


Application No.: US20080102102A1  Published: 01/May/2008

Title: Methods And Compositions For Decreasing Saliva Production

Applicant/Assignee: NEUROHEALING PHARMACEUTICALS, INC

Application No.: 11/795210   Filing Date: 19/Jan/2006

Abstract:

The invention provides methods and compositions comprising an anti-cholinergic agent for decreasing saliva production and treating sialorrhea.

Priority: US20050645147P Applic. Date: 2005-01-19; WO2006US02206 Applic. Date: 2006-01-19

Inventor: MERELLO MARCELO [AR]; FARBER NEAL M [US]; RON EYAL S [US]


Application No.: US20080102115A1  Published: 01/May/2008

Title: Modified coagulation factor IX polypeptides and use thereof for treatment

Applicant/Assignee:

Application No.: 11/818985   Filing Date: 15/Jun/2007

Abstract:

Provided are modified factor IX (FIX) polypeptides and methods of generating modified FIX polypeptides. Also provided are pharmaceutical compositions, including compositions formulation for oral administration, that contain the modified FIX polypeptides, and methods of treatment using modified FIX polypeptides.

Priority: US20060815113P Applic. Date: 2006-06-19

Inventor: OYHENART JORGE [AR]; GALLET XAVIER [FR]; BORRELLY GILLES [FR]; GUYON THIERRY [FR]; VEGA MANUEL [FR]; DRITTANTI LILA [FR]


Application No.: US20080102414A1  Published: 01/May/2008

Title: POSTERIOR BITE RAMPS, KITS, AND METHODS OF USE TO CORRECT CLASS II AND/OR CLASS III MALOCCLUSIONS

Applicant/Assignee:

Application No.: 11/553909   Filing Date: 27/Oct/2006

Abstract:

A posterior bite ramp includes a tooth-attachment element and ramp element connected to the tooth-attachment element by a connection web. The tooth-attachment element is sized and configured for bonding to the lingual surface of a person's molar, behind the tooth, while the ramp element may be hingedly or bendably adjustable relative to the tooth-attachment element so as to form a ramp angle between the ramp element and an occlusal plane that is substantially perpendicular to the tooth-attachment element. The ramp element provides a ramp at a desired angle for engaging a corresponding molar of the opposite dental arch when the person's mouth is closed. The engagement between the ramp element and the corresponding molar of the opposite dental arch causes the lower jaw to move forward or backward relative to the upper jaw, thereby incrementally correcting a Class II or Class III malocclusion.

Priority:

Inventor: ABELS NORBERT [DE]; BACKES CLAUS H [DE]


Application No.: US20080103214A1  Published: 01/May/2008

Title: Novel Composition For Easing Human Childbirth

Applicant/Assignee: HCB HAPPY CHILD BIRTH HOLDING AG

Application No.: 11/718995   Filing Date: 10/Nov/2005

Abstract:

The present invention relates to a composition having a lubricant effect for use in particular during human vaginal delivery.

Priority: DE200410054552 Applic. Date: 2004-11-11; WO2005EP12058 Applic. Date: 2005-11-10

Inventor: SCHAUB ANDREAS F [CH]


Application No.: US20080103223A1  Published: 01/May/2008

Title: Total etch dental adhesive composition

Applicant/Assignee:

Application No.: 11/879671   Filing Date: 18/Jul/2007

Abstract:

Dental adhesive composition having a pH of at least 5, which comprises an aqueous solution containing (a) a polymerizable N-substituted alkyl acrylic or acrylic acid amide monomer

(b) a water-soluble polymerizable carboxylic acid

and (c) a water-soluble organic solvent.

Priority: US20060807636P Applic. Date: 2006-07-18

Inventor: KLEE JOACHIM E [DE]; LEHMANN UWE [DE]


Application No.: US20080103229A1  Published: 01/May/2008

Title: Dental composition with improved light stability

Applicant/Assignee:

Application No.: 12/002550   Filing Date: 18/Dec/2007

Abstract:

Dental composition having an improved light and thermal stability, including a mixture of at least a polymerizable resin, at least a polymerizable monomer, at least a polymerization initiator and/or a sensitizer and stabilizer, and at least an organic and/or inorganic filler and pigments in a content of 0 to 90 percent and at least one of the stable radicals.

Priority: US2003-452739 Applic. Date: 2003-06-02; US2001-754162 Applic. Date: 2001-01-04

Inventor: WALZ UWE [DE]; KLEE JOACHIM E [DE]


Application No.: US20080104786A1  Published: 08/May/2008

Title: Oral Care Toothbrush

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 11/932358   Filing Date: 31/Oct/2007

Abstract:

An oral care toothbrush includes a head mounted to one end of the handle containing a plurality of oral care elements. An oral care accessory is mounted to the opposite end of the handle. An oral care material dispenser is mounted in the head within the cleaning field defined by the oral care elements. The toothbrush is preferably made of small size and of lightweight so as to be readily portable for use away from the home.

Priority: US2004-843135 Applic. Date: 2004-05-11; WO2003US27455 Applic. Date: 2003-09-04; US20020408321P Applic. Date: 2002-09-05

Inventor: HOHLBEIN DOUGLAS J [US]; KEMP JAMES [US]; SORRENTINO ALAN V [US]; MINTEL THOMAS [US]


Application No.: US20080105693A1  Published: 08/May/2008

Title: Foldable Air Insulating Sleeve

Applicant/Assignee:

Application No.: 11/935181   Filing Date: 05/Nov/2007

Abstract:

A foldable air insulating sleeve for insulating beverage and food containers is herein provided. More particularly, the foldable air insulating sleeve secures a cup in a manner that leaves a pocket of air surrounding the cup. This provides for improved temperature regulation and sufficient thermal insulation to assist the user in firmly grasping and handling the cup despite excess heat or condensation caused by the temperature of the cup's contents. Because the bases of most disposable cups are narrower than their respective rims, more air and thus greater insulation is found towards the bottom of cups secured by foldable air insulating sleeves. The wider base also gives such cups more stability. Printable material can also be affixed on the foldable air insulating sleeve's outer surface for advertising or other purposes.

Some embodiments of the foldable air insulating sleeve include a lid to further improve thermal insulation.

Priority: US2003-459337 Applic. Date: 2003-06-11

Inventor: HECHMATI LAURENT [US]


Application No.: US20080107597A1  Published: 08/May/2008

Title: ISOLATION OF ANTIBODIES THAT CROSS-REACT AND NEUTRALIZE RANKL ORIGINATING FROM MULTIPLE SPECIES

Applicant/Assignee: ANAPTYS BIOSCIENCES, INC

Application No.: 11/863845   Filing Date: 28/Sep/2007

Abstract:

The invention provides specific binding members (e.g., antibodies or antigen-binding fragments thereof) which bind to RANKL originating from multiple species. An epitope recognized by the specific binding members can be selected from surface exposed loop domains that bind to and activate its cognate receptor, RANK (Receptor Activator of NFkB), on the surface of osteoclast precursors and other cell types. The invention provides peptides for generating such anti-RANKL antibodies, including murine sequences, other non-human sequences and cross-reactive peptides. The specific binding members are useful in the diagnosis and treatment of lytic bone diseases, including osteoporosis, rheumatoid arthritis, bone metastasis and hypercalcemia of malignancy, glucocorticoid-induced bone loss, a periodontal disease or condition, a cancer and Juvenile Paget's Disease. The binding members can also be used in therapy in combination with chemotherapeutics or anti-cancer agents and/or with other antibodies or antigen-binding fragments thereof.

Priority: US2007-622928 Applic. Date: 2007-01-12; US20060758319P Applic. Date: 2006-01-12

Inventor: BOYLE WILLIAM J [US]


Application No.: US20080107646A1  Published: 08/May/2008

Title: METHOD FOR AMELIORATING PRURITUS

Applicant/Assignee:

Application No.: 11/848272   Filing Date: 31/Aug/2007

Abstract:

A method for preventing, treating, or ameliorating pruritus caused by skin, mucosa, or systemic disorder. The method comprises administering to a subject with pruritus or topically applying to an affected area with pruritus an effective amount of a formulation consisting essentially of a phenylbutyric acid or short-chain fatty acid derivative and a pharmaceutically acceptable carrier, salt or solvate thereof.

Priority: US2006-499936 Applic. Date: 2006-08-07; US2004-798119 Applic. Date: 2004-03-11; US2002-205738 Applic. Date: 2002-07-25

Inventor: CHUNG YIH-LIN [TW]; PUI NAM-MEW [TW]; CHANG WEI-WEI [US]


Application No.: US20080107707A1  Published: 08/May/2008

Title: POLYMERIZABLE ANTIMICROBIAL COMPOSITION

Applicant/Assignee: REGENTS OF THE UNIVERSITY OF COLORADO

Application No.: 11/774047   Filing Date: 06/Jul/2007

Abstract:

The present invention provides a polymerizable antimicrobial composition and a method for using the same. The polymerizable antimicrobial composition of the invention comprises an antimicrobial compound, a linker, and a polymerizable function group.

Priority: US20060806678P Applic. Date: 2006-07-06

Inventor: LAWSON MCKINLEY C [US]; ANSETH KRISTI S [US]


Application No.: US20080108016A1  Published: 08/May/2008

Title: DENTAL PROSTHESIS

Applicant/Assignee: ETKON CENTRUM FUR DENTALE CAD/CAM-TECHNOLOGIE AG

Application No.: 11/936222   Filing Date: 07/Nov/2007

Abstract:

The invention relates to a dental prosthesis identification means. The invention furthermore relates to a method and a device for manufacturing a dental prosthesis, whereby in this method and device, an identification means is formed or the formation of such an identification means is possible.

Priority: DE200610052478 Applic. Date: 2006-11-07

Inventor: HOLZNER STEPHAN [DE]; WEBER GERHARD [DE]


Application No.: US20080108497A1  Published: 08/May/2008

Title: METAL-RICH SILICEOUS COMPOSITIONS AND METHODS OF PRODUCING SAME

Applicant/Assignee:

Application No.: 11/557548   Filing Date: 08/Nov/2006

Abstract:

A modified sol-gel method to create metal-rich siliceous material, such as colloidal silica or aluminosilicate particles is disclosed. Initially, the metal salt of choice is added to a silicic acid solution or a silicic acid solution containing aluminum salt. The aluminum is added to vary the metal-support interaction as it forms Al-O-Si linkages within the silica matrix. Besides aluminum, other metals can be added that form M-O-Si (M=Ti, B, etc.) linkages, which do not become reduced when treated with a reducing agent. Once the metal, silicic acid and/or aluminum salt is generated, it is subjected to colloidal growth by addition to a basic heel. Upon colloidal synthesis, the metal salt containing colloidal particle is left as is to maximize colloidal stability or is reduced with hydrazine to produce the zero valence metal-containing colloidal particle. Keeping a particle colloidal before use may be an effective method of forming a catalyst material as it can be easily spray-dried or mixed with other materials for extruded catalyst particles.

Priority:

Inventor: HOLLAND BRIAN T [US]


Application No.: US20080109029A1  Published: 08/May/2008

Title: Angioplasty Balloon with Therapeutic/Aspiration Channel

Applicant/Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN

Application No.: 11/935131   Filing Date: 05/Nov/2007

Abstract:

An angioplasty balloon catheter with an added channel for delivering medication or removing body fluids distal to the site of angioplasty is disclosed. The balloons are especially useful in the treatment of occlusions in saphenous vein grafts, the coronary and carotid arteries, arteries arising from the aorta and branches thereof and in veins flowing to the heart or their tributaries and sub tributaries thereof.

Priority: US20060857082P Applic. Date: 2006-11-06

Inventor: GURM HITINDER [US]


Application No.: US20080109973A1  Published: 15/May/2008

Title: Personal care products and methods

Applicant/Assignee:

Application No.: 11/983287   Filing Date: 08/Nov/2007

Abstract:

In one embodiment, an oral-care system is provided. The oral-care system includes an electric toothbrush having a motor, a power source in electrical communication with the motor, and a bristle holder operatively connected to the motor. A display is in data communication with the electric toothbrush.

Priority: US20060859226P Applic. Date: 2006-11-15; US20070920698P Applic. Date: 2007-03-29

Inventor: FARRELL MARK E [US]; CHENVAINU ALEXANDER T [US]; ORTINS MARC P [US]; DENISHENKO VADIM [US]; DE CASTRO JOSE TADEO V [US]; TRAWINSKI PETER H R [DE]; HILSCHER ALEXANDER [DE]; SCHREMPEL BERT [DE]; STRATMANN MARTIN [DE]; SAGEL PAUL A [US]; BRAUN PHILLIP M [US]


Application No.: US20080110094A1  Published: 15/May/2008

Title: MULLION JOINT BETWEEN TWO FRAME MEMBERS OF A WINDOW OR DOOR FRAME

Applicant/Assignee: OMNIGLASS LTD

Application No.: 11/558531   Filing Date: 10/Nov/2006

Abstract:

A mullion for a window frame is formed by two frame members back to back to form the mullion. The facing surfaces are connected by providing aligned first and second recesses therein where each of the recesses has a mouth at the which is narrower than a base and has a connecting member along the aligned recesses with a portion of the connecting member within each recess as a loose fit. Each connecting member has associated with it an insert member with an insert portion between the outer surfaces of the first and second frame members forcing the outer surfaces apart to tighten the connecting member and a cover portion covering a junction between the side surfaces.

Priority: CA20062568062 Applic. Date: 2006-11-09

Inventor: DAVIES LAURENCE W [CA]


Application No.: US20080111106A1  Published: 15/May/2008

Title: NON-SILICA CONTAINING IMPRESSION AND CASTING MATERIALS

Applicant/Assignee:

Application No.: 12/014146   Filing Date: 15/Jan/2008

Abstract:

A chemical composition for use in preparing health related impressions, such as dental, medical, and prosthetic impressions is provided. The chemical composition may include a water-soluble alginate, an alginate insolubilizing cation-containing salt, a cation-release moderating component, and a cellulosic filler.

Priority: US2006-308885 Applic. Date: 2006-05-22

Inventor: RENN DONALD W [US]


Application No.: US20080112901A1  Published: 15/May/2008

Title: Dental Compositions with Sensitivity Relief

Applicant/Assignee: DISCUS DENTAL, LLC

Application No.: 11/927252   Filing Date: 29/Oct/2007

Abstract:

A one-component prescription fluoride treatment composition having both fluoride efficacy and sensitivity relief is disclosed. The composition includes at least one metal fluoride and a nerve desensitizing agent such as potassium nitrate. The invention further includes a composition having at least one metal fluoride less than about 1.15% by weight of at least one metal fluoride

less than about 5 percent by weight of at least one alkali metal salt having desensitizing effect

at least one carrier

and at least one foaming agent that has thickening property. The composition may be formulated into a gel, a paste or any other convenient form, some of which contain abrasives.

Priority: US2005-173632 Applic. Date: 2005-06-30; US20040585224P Applic. Date: 2004-07-02

Inventor: MACDONALD JEFF [US]; HAYMAN ROBERT [US]


Application No.: US20080112902A1  Published: 15/May/2008

Title: Protective Dental Balm and Method

Applicant/Assignee:

Application No.: 11/940318   Filing Date: 14/Nov/2007

Abstract:

A dental balm composition and method prevents damage to teeth which are prone to prolonged exposure to air or other drying conditions and which are therefore susceptible to tooth decay. The dental balm composition and uses an active decay preventing agent such as fluoride ion, xylitol or glycerin dispersed in a water insoluble adhesive and protective balm base such as petrolatum along with optional thickeners, flavorants and the like. The method of damage prevention applies the balm, such as by swab or finger, to the exposed surfaces of the subject's front teeth prior to vigorous physical activity, exercise, prolonged episodes of mouth breathing, or other harsh or deleterious conditions including drying conditions during strenuous periods of exercise or tooth whitening procedures.

Priority: US2005-113855 Applic. Date: 2005-04-25

Inventor: PERECHOCKY JOSEPH [US]


Application No.: US20080113313A1  Published: 15/May/2008

Title: SELF CONTAINED COMPOSITION ENHANCING DENTAL TRAY

Applicant/Assignee:

Application No.: 11/940492   Filing Date: 15/Nov/2007

Abstract:

The present invention relates to dental trays including a light source, a heat element or a combined light source and heating element that serves to enhance the treatment capacity of the composition. The dental tray is self-contained meaning that no external attachments that project from the mouth during use are required.

Priority: US20060865877P Applic. Date: 2006-11-15

Inventor: KHOURI LOUIE [US]


Application No.: US20080113958A1  Published: 15/May/2008

Title: Modulators of muscarinic receptors

Applicant/Assignee: VERTEX PHARMACEUTICALS INCORPORATED

Application No.: 11/894092   Filing Date: 20/Aug/2007

Abstract:

The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

Priority: US20060838701P Applic. Date: 2006-08-18

Inventor: DAVIES ROBERT J [US]; XU JINGWANG [US]


Application No.: US20080114061A1  Published: 15/May/2008

Title: Diphenylethylene compounds and uses thereof

Applicant/Assignee: CELGENE CORPORATION

Application No.: 11/983179   Filing Date: 07/Nov/2007

Abstract:

The present invention relates to Diphenylethylene Compounds and compositions comprising a Diphenylethylene Compound. The present invention also relates to methods for preventing or treating various diseases and disorders by administering to a subject in need thereof one or more Diphenylethylene Compounds. In particular, the invention relates to methods for preventing or treating cancer or an inflammatory disorder by administering to a subject in need thereof one or more Diphenylethylene Compounds. The present invention further relates to articles of manufacture and kits comprising one or more Diphenylethylene Compounds.

Priority: US2004-794931 Applic. Date: 2004-03-05; US20030452460P Applic. Date: 2003-03-05

Inventor: MULLER GEORGE W [US]; PAYVANDI FARIBOURZ [US]; ZHANG LING H [US]; ROBARGE MICHAEL J [US]; CHEN ROGER [US]; MAN HON-WAH [US]


Application No.: US20080114221A1  Published: 15/May/2008

Title: Multifunction health apparatus

Applicant/Assignee:

Application No.: 11/598128   Filing Date: 13/Nov/2006

Abstract:

The present invention provides a multifunction health device, which comprises a meter and a platform. The meter has two electrodes arranged separately at its two sides, and another electrode arranged in its bottom. The platform has four electrodes arranged in its top face, and a pressure sensor arranged in its inside. With or without some parts assisting, the single use of the meter can function as an ECG detector, a TENS machine, a thermometer, and a first sphygmomanometer. Connecting with the platform, the meter and the platform can function as an ECG detector, a weight scale, and a body composition estimator. Further, the meter can alternatively connect with a chassis thus functioning as a second sphygmomanometer, a stethoscope, a glucose meter, or a pulse oximeter.

Priority:

Inventor: TSO SHUN-WUN [TW]


Application No.: US20080115244A1  Published: 15/May/2008

Title: Method for producing immunoglobulins containing protection proteins and their use

Applicant/Assignee: THE REGENTS OF UNIVERSITY OF CALIFORNIA

Application No.: 11/605720   Filing Date: 28/Nov/2006

Abstract:

The immunoglobulins of the present invention are useful therapeutic immunoglobulins against mucosal pathogens such as S. mutans. The immunoglobulins contain a protection protein that protects the immunoglobulins in the mucosal environment. The invention also includes the greatly improved method of producing immunoglobulins in plants by producing the protection protein in the same cell as the other components of the immunoglobulins. The components of the immunoglobulin are assembled at a much improved efficiency. The method of the invention allows the assembly and high efficiency production of such complex molecules. The invention also contemplates the production of immunoglobulins containing protection proteins in a variety of cells, including plant cells, that can be selected for useful additional properties. The use of immunoglobulins containing protection proteins as therapeutic antibodies against mucosal and other pathogens is also contemplated.

Priority: US2004-781989 Applic. Date: 2004-02-18; US2000-717888 Applic. Date: 2000-11-20; US1999-312157 Applic. Date: 1999-05-14; US1995-434000 Applic. Date: 1995-05-04; US1994-367395 Applic. Date: 1994-12-30

Inventor: HIATT ANDREW C [US]; MA JULIAN K-C [GB]; LEHNER THOMAS [GB]


Application No.: US20080115465A1  Published: 22/May/2008

Title: CONTAINER MANAGEMENT SYSTEM

Applicant/Assignee: EGGS OVERNIGHT, INC

Application No.: 11/941366   Filing Date: 16/Nov/2007

Abstract:

Provided is a method for shipping a parcel from a primary to a secondary location in a reusable container, and returning the container to a tertiary location. The parcel is packaged in the container which includes a label construction. The label construction includes a base substrate for securing to the container, a sleeve overlaying the base substrate, and a transparent viewing window having an exposed surface for removably receiving an address label. A first removable label is adhered to the transparent viewing window and includes information corresponding to an address for the secondary location. A second removable label is placed inside the sleeve and includes information corresponding to an address for a tertiary location. The package is delivered to the secondary location where it is un-packed and the first label is removed thereby exposing the second label for viewing through the window for delivery to the tertiary location.

Priority: WO2005US09400 Applic. Date: 2005-03-18; US20040554559P Applic. Date: 2004-03-18

Inventor: DICKINSON KENT H [US]


Application No.: US20080115814A1  Published: 22/May/2008

Title: Endoscope cleaning/disinfecting apparatus

Applicant/Assignee: OLYMPUS MEDICAL SYSTEMS CORP

Application No.: 11/716249   Filing Date: 09/Mar/2007

Abstract:

An endoscope cleaning/disinfecting apparatus of the present invention includes a cleaning tub, a chemical solution tank for storing a germicide, a chemical solution collection pipe, a chemical solution pipe, a feed pipe, a germicide bottle tray which can be drawn from the body of the cleaning/disinfecting apparatus, and a control unit for performing control to prepare the germicide by mixing a basis, a buffering agent, and a diluent. The germicide bottle tray includes a storage part which stores at least a first bottle body out of the first bottle body for storing the basis or a second bottle body for storing the buffering agent, and a detection portion for outputting a detection signal in a state in which the bottle body is stored in the storage part. The control unit performs control based on the detection signal outputted from the detection portion to prepare the germicide.

Priority: WO2006JP323038 Applic. Date: 2006-11-17

Inventor: HASEGAWA HITOSHI [JP]; KOTANI KOJIRO [JP]


Application No.: US20080118420A1  Published: 22/May/2008

Title: Disinfectant bottle and endoscope cleaning and disinfecting apparatus

Applicant/Assignee: OLYMPUS MEDICAL SYSTEMS CORPORATION OLYMPUS MEDICAL SYSTEMS CORP

Application No.: 11/716408   Filing Date: 08/Mar/2007

Abstract:

An endoscope cleaning and disinfecting apparatus of the present invention includes: a bottle body, including, a rigid portion with a mouth portion, and a deformable portion which is in a first shape while the disinfectant being stored therein and is deformable from the first shape to a second shape upon being compressed when the disinfectant is discharged therefrom

and a disinfectant tray having a housing section which can be pulled out of the apparatus body and into which the bottle body is housed, the disinfectant tray being provided with a housing space for a first slide member which allows the housing section to slide relative to the apparatus body and a housing space for a second slide member which is slidable relative to the first slide member.

Priority: WO2006JP323037 Applic. Date: 2006-11-17

Inventor: KOTANI KOJIRO [JP]; HASEGAWA HITOSHI [JP]


Application No.: US20080118443A1  Published: 22/May/2008

Title: Novel Odorant Compounds, Synthesis Method, and Uses of Said Compounds

Applicant/Assignee: V. MANE FILS

Application No.: 11/795496   Filing Date: 13/Jan/2006

Abstract:

A compound of general formula (I) with or without the double bond illustrated by the dotted line. In formula (I), X is a CHO, CH2OH, CH2OC(O)R or CH(OR)2 group, and R represents a linear or branched C1-C5 alkyl or alkenyl chain. The synthesis method for the compound, and especially the 6,8-dimethyl-non-7-enal (1) prepared by the hydroformylation of the 5,7-dimethyl-octa-1,6-diene is also disclosed, as well as compositions containing the compounds of formula (I). Due to the odorant properties thereof, the compounds are highly useful in perfumery, especially for cosmetic products and household products.

Priority: FR20050000551 Applic. Date: 2005-01-19; WO2006FR00080 Applic. Date: 2006-01-13

Inventor: JAUNKY PIOTR [FR]; MANE JEAN [FR]; SCHROEDER MARTIN [GB]


Application No.: US20080118444A1  Published: 22/May/2008

Title: Lactobacillus paracasei-containing product

Applicant/Assignee: GENMONT BIOTECH INC

Application No.: 11/637711   Filing Date: 13/Dec/2006

Abstract:

A Lactobacillus paracasei-containing product used for inhibiting dental diseases caused by bacteria is provided, which comprises a plurality of Lactobacillus paracasei for inhibiting the growth of bacteria of dental diseases. Particularly, foods, oral hygiene products or oral treatment medicine containing the Lactobacillus paracasei when being administered or applied to a user can inhibit or reduce the number of pathogens of dental caries and periodontal diseases in oral cavity of the user, thereby achieving the efficacy of preventing dental diseases, such as dental caries and periodontal diseases.

Priority: TW20060129265 Applic. Date: 2006-08-09

Inventor: HSU CHING-HSIANG [TW]; CHEN YA-HUI [TW]; WANG YING-YU [TW]; LAI DING-YING [TW]; HSIEH FENG-CHING [TW]


Application No.: US20080118445A1  Published: 22/May/2008

Title: Dental Appliance Cleaners and Methods for Making and Using Them

Applicant/Assignee: CAO GROUP, INC

Application No.: 12/019493   Filing Date: 24/Jan/2008

Abstract:

The addition of the Iodide ion by way of iodide salts, such as sodium iodide and potassium iodide, to a peroxide such as hydrogen peroxide in a basic medium yields free radical oxygen and water

generating large amounts of heat and depleting the Hydrogen Peroxide in a matter of minutes. The free radical oxygen generated in this reaction can be utilized to oxidize organic molecules that produce offending stains on select items, including artificial teeth and other dental appliances. Once the free radical oxygen has oxidized the offending molecule the color is lost and the solubility changes allowing any loose fragments of the offending molecule to be washed away in the solvent. The iodide ion catalyzes the reaction allowing for precise control over the speed at which the stain is removed without the need for other expensive, cumbersome energy adding equipment such as lights, lasers, heat sources, etc.

Priority: US2004-922804 Applic. Date: 2004-08-20

Inventor: LARSEN ROBERT K [US]; OSTLER CALVIN D [US]


Application No.: US20080118482A1  Published: 22/May/2008

Title: TREATING MOUTH ULCER WITH LIVE BACTERIA

Applicant/Assignee: QINGDAO EAST SEA PHARMACEUTICALS, LTD

Application No.: 11/763072   Filing Date: 14/Jun/2007

Abstract:

This invention relates to using live beneficial bacteria for treating mouth ulcer.

Priority: CN20061138487 Applic. Date: 2006-11-17

Inventor: CUI YUNLONG [CN]


Application No.: US20080118569A1  Published: 22/May/2008

Title: Injectable microspheres for tissue construction

Applicant/Assignee: BIOSPHERE MEDICAL, INC

Application No.: 12/009181   Filing Date: 16/Jan/2008

Abstract:

The present invention relates to injectable compositions comprising biocompatible, hydrophilic, non-toxic and substantially spherical microspheres associated with stem cells useful for tissue construction and generation. The invention also relates to methods of tissue construction and generation, for the treatment of various tissue damage and defects, using the injectable compositions.

Priority: US2002-220984 Applic. Date: 2002-12-12; WO2001US08528 Applic. Date: 2001-03-15; US20000190542P Applic. Date: 2000-03-20

Inventor: VOGEL JEAN-MARIE [US]; BOSCHETTI EGISTO [FR]


Application No.: US20080118570A1  Published: 22/May/2008

Title: POLYMER COATED DRUG-ION EXCHANGE RESINS AND METHODS

Applicant/Assignee:

Application No.: 11/561723   Filing Date: 20/Nov/2006

Abstract:

Included are compositions, and methods of making, coated controlled-release drug and ion exchange resin form complexes. Methacrylate coatings, which can be free of plasticizers particularly with Eudragit(R) NE type polymer, are preferred to enhance the control of drug release from the drug-resin complexes. Liquid formulations including the coated resin forms and a chelating agent to inhibit degradation are also included.

Priority:

Inventor: LIU ZHI [US]; CHEN BEI [US]; GAO DANCHEN [US]; RAO MUKTI S [US]; USAYAPANT ARUNYA [US]


Application No.: US20080118591A1  Published: 22/May/2008

Title: Bactericidal Formulations

Applicant/Assignee:

Application No.: 11/719261   Filing Date: 15/Nov/2005

Abstract:

The invention relates to bactericidal formulations that come into contact with human body, particularly wash formulations including liquid soaps, comprising perfume ingredients active against gram-negative bacteria. Such compositions contact the target site, for example the skin surface, only for a short time, usually not longer than 30 seconds. Therefore the antibacterial action has to be of the bactericidal type and rapid. Furthermore, the bactericidal activity has to be sufficiently high to ensure an effect even when applied to wet substrates that will dilute the bactericidal formulation.

Priority: GB20040025305 Applic. Date: 2004-11-17; WO2005CH00676 Applic. Date: 2005-11-15

Inventor: NATSCH ANDREAS [CH]


Application No.: US20080118882A1  Published: 22/May/2008

Title: Moisture resistant pressure sensitive adhesives for orthodontic applications

Applicant/Assignee:

Application No.: 11/601106   Filing Date: 17/Nov/2006

Abstract:

A moisture resistant pressure sensitive adhesive for orthodontic application. Specifically, in accordance with one embodiment, a pressure sensitive adhesive (PSA) composition comprises a polymer base, and at least one bio-compatible hydrophobic tackifier. The PSA composition is structured such that the PSA composition is suitable for use in an oral environment.

Priority:

Inventor: SU LI-HUNG [US]


Application No.: US20080119391A1  Published: 22/May/2008

Title: Method for treating wounds to promote healing

Applicant/Assignee: MEDICAL NUTRITION USA, INC

Application No.: 11/985627   Filing Date: 16/Nov/2007

Abstract:

A method of treating a mammal to promote wound healing in the mammal in need thereof, comprising orally administering to the mammal an effective amount of a palatable, concentrated protein composition comprising an effective amount of hydrolyzed gelatin and tryptophan, and an ingestible carrier, the composition comprising the essential amino acids required by the mammal. Palatability is preferably achieved by the use of an effective amount of a sweetener. The method is particularly useful for treating wounds resulting from decubitus ulcers and bariatric surgery.

Priority: US2003-689236 Applic. Date: 2003-10-20; US20020422164P Applic. Date: 2002-10-29

Inventor: GANS ARNOLD M [US]


Application No.: US20080119473A1  Published: 22/May/2008

Title: Compounds for Nonsense Suppression, and Methods for Their Use

Applicant/Assignee:

Application No.: 11/577189   Filing Date: 13/Oct/2005

Abstract:

The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.

Priority: US20040617670P Applic. Date: 2004-10-13; US20040617633P Applic. Date: 2004-10-13; US20040617634P Applic. Date: 2004-10-13; US20040617655P Applic. Date: 2004-10-13; US20040617653P Applic. Date: 2004-10-13; US20040624170P Applic. Date: 2004-11-03; WO2005US36764 Applic. Date: 2005-10-13

Inventor: ALMSTEAD NEIL [US]; KARP GARY M [US]; WILDE RICHARD [US]; WELCH ELLEN [US]; REN HONGYU [US]


Application No.: US20080121240A1  Published: 29/May/2008

Title: Dust Mask

Applicant/Assignee: GOODY PRODUCTS, INC

Application No.: 11/563448   Filing Date: 27/Nov/2006

Abstract:

The invention is directed to a scented dust mask configured to provide a pleasant scent while being worn on the face of a user. The dust mask includes outer and inner layers of material shaped to cover the nose and mouth of the user, and connected to each other about the outer edges such that the layers of material define a pocket therebetween. The layers of material are configured to filter particulate matter from the air as the air passes through the material. The dust mask further includes a quantity of a scented material disposed and retained within the pocket defined by the inner and outer layers of material, with the scent of the scented material being detectable by the user when the dust mask is worn. The dust mask may further include a connection mechanism configured to retain the dust mask against the face of the user when the dust mask is worn.

Priority:

Inventor: SCHWARZ JEREMIAH [US]


Application No.: US20080121653A1  Published: 29/May/2008

Title: Sealing Condition of Multiple-Container, in Particular Double-Tube, Packages Designed for Instant Preparation

Applicant/Assignee: CEBAL SAS

Application No.: 11/915791   Filing Date: 22/May/2006

Abstract:

A double dispensing container including an outer container and an inner container, each container including a body and a head provided with a neck and a shoulder linking the neck to the body, the neck having a side wall and one or more dispensing orifices, the neck of the inner container being housed inside the neck of the outer container and having a section such that it provides one of more outflow passages for a pasty product A and, in combination with the inner surface of the outer container neck, one or more outflow passages for a pasty product B emerging onto a single or multiple orifice dispensing the product B. The inner neck is extended by a summit portion which is linked to the inner neck via a thin annular zone and which closes the single or multiple orifice dispensing product A.

Priority: FR20050005449 Applic. Date: 2005-05-30; WO2006FR01163 Applic. Date: 2006-05-22

Inventor: ZAKRZEWSKI HERVE [FR]; KERMAN ERIC [FR]


Application No.: US20080124284A1  Published: 29/May/2008

Title: Synthetic peptide constructs for the diagnosis and treatment of periodontitis associated with Porphyromonas gingivalis

Applicant/Assignee: THE UNIVERSITY OF MELBOURNE

Application No.: 11/731307   Filing Date: 30/Mar/2007

Abstract:

The present invention relates to an oral composition and an immunogenic composition for the suppression of the pathogenic effects of the intra-oral bacterium Porphyromonas gingivalis associated with periodontal disease.

Priority: AU1997PO06528 Applic. Date: 1997-04-30; US2003-387977 Applic. Date: 2003-03-12; US2000-423056 Applic. Date: 2000-03-22; WO1998AU00311 Applic. Date: 1998-04-30

Inventor: REYNOLDS ERIC CHARLES [AU]; O'BRIEN-SIMPSON NEIL MARTIN [AU]; SLAKESKI NADA [AU]


Application No.: US20080124303A1  Published: 29/May/2008

Title: Methods and compositions for treatment of viral infections

Applicant/Assignee: CAVIT SCIENCES, INC

Application No.: 11/827491   Filing Date: 12/Jul/2007

Abstract:

A novel method of treating and preventing viral diseases is provided. In particular, the present invention relates to compositions and methods for inhibition of viral infections and the diseases associated with such viral infections. More particularly, the present invention relates to the inhibitory compounds comprising naturally occurring and man-made compositions comprising a substance exhibiting Tubercin and/or SSM activity or a functional derivative thereof.

Priority: US2005-298629 Applic. Date: 2005-12-12

Inventor: KING COLM [US]


Application No.: US20080124384A1  Published: 29/May/2008

Title: Heteroaryl Substituted Piperazinyl-Pyridine Analogues

Applicant/Assignee:

Application No.: 11/795651   Filing Date: 19/Jan/2006

Abstract:

Substituted biaryl piperazinyl-pyridine analogues are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20050645496P Applic. Date: 2005-01-19; WO2006US02194 Applic. Date: 2006-01-19

Inventor: BLUM CHARLES A [US]


Application No.: US20080125394A1  Published: 29/May/2008

Title: Oral Compositions for Absorption of Phosphorus Compounds

Applicant/Assignee: CM&D PHARMA LIMITED

Application No.: 11/792047   Filing Date: 29/Nov/2005

Abstract:

The present invention provides medicaments useful for reducing phosphorus serum level, especially in those subjects affected from hyperphosphatemia. More specifically, the present invention relates to pharmaceutical compositions to be administered by oral route in fasting periods, in order to absorb phosphorus compounds from fluids of the enteric tract, especially from saliva.

Priority: IT2004ME00015 Applic. Date: 2004-12-07; WO2005EP56289 Applic. Date: 2005-11-29

Inventor: SAVICA VINCENZO [IT]


Application No.: US20080125466A1  Published: 29/May/2008

Title: Aryl-Substituted Benzo[D]Isothiazol-3-Ylamine Analogues

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 10/564263   Filing Date: 09/Jul/2004

Abstract:

Aryl-substituted benzo[d]isothiazol-3-ylamine analogues) are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20030485958P Applic. Date: 2003-07-10; WO2004US21914 Applic. Date: 2004-07-09

Inventor: BLUM CHARLES A [US]; ZHENG XIAOZHANG [US]


Application No.: US20080125477A1  Published: 29/May/2008

Title: 7-(ACRYLOYL) INDOLE COMPOSITIONS AND METHODS OF MAKING AND USING SAME

Applicant/Assignee: DECODE GENETICS, EHF

Application No.: 11/748897   Filing Date: 15/May/2007

Abstract:

The present invention is directed to pharmaceutical compositions of 7-(acryloyl)indoles, such as 4,5 -Dichloro-thiophene-2-sulfonic acid [(E)-3-[1-(2,4-dichlorophenylmethyl)-5-fluoro-3-methyl-1H-indol-7-yl]-acryloyl]amide (DTSI), having a structure shown below. The invention is also directed to methods of treatment utilizing formulations of the DTSI and processes of preparation of the formulations.

Priority: US20060800806P Applic. Date: 2006-05-16

Inventor: SINGH JASBIR [US]; DUAN MATT SHAOMING [US]; THORSTEINSSON THORSTEINN [US]; FRIEDMAN MITCHELL B [US]; GURNEY MARK [US]


Application No.: US20080128941A1  Published: 05/Jun/2008

Title: PROCESS FOR THE ADDITIVATION OF SYNTHETIC FIBRES, ARTIFICIAL FIBRES AND POLYMERS WITH SPECIAL PROPERTIES

Applicant/Assignee:

Application No.: 11/938337   Filing Date: 12/Nov/2007

Abstract:

A process for the additivation of synthetic fibres, artificial fibres and polymers conferring special properties to them, the process comprising the following steps: the encapsulation of an additive in the pores of a porous material

the incorporation of particles of the porous material (capsules) into the polymer matrix of the fibre

and spinning of the fibre

the capsule withstanding the temperatures and other conditions of the different manufacturing processes which the fibres might undergo and the introduction of the additive into the polymer matrix thereof, characterised in that the porous material is a metal oxide, a zeolite, an aluminophosphate, clay, a carbon material, a hybrid organic-inorganic material or a porous polymer. The invention is an improvement in the additivation process of fibres and polymers in terms of the nature of the capsules used, the increase in the storage capacity of additives thereof, the process of incorporating the capsules into the polymer matrix of the fibres and the fact that the present invention refers to an industrial process.

Priority: EP20060380293 Applic. Date: 2006-11-14

Inventor: LOPEZ MIGUEL ANGEL CABALLERO [US]; LASIERRA PATRICIA ZAGALAZ [US]; GUAJARDO SERGIO JOSE SEGURA [US]; CAMAS MARIA ELENA PIERA [US]; GARCIA EDUARDO PEREZ [US]; ARISO CARLOS TELLEZ [US]; CERESUELA JOAQUIN CORONAS [US]; RAMIRO JESUS SANTAMARIA [US]


Application No.: US20080131380A1  Published: 05/Jun/2008

Title: Methods of Whitening Teeth

Applicant/Assignee: BRITESMILE PROFESSIONAL, LLC

Application No.: 11/927636   Filing Date: 29/Oct/2007

Abstract:

The present invention relates to improved dental compositions and methods for bleaching teeth. More specifically, this invention is directed towards hydrogen peroxide-containing compounds that are maintained at a substantially constant pH range of 6.0-10.0 during the tooth-bleaching procedure in the presence of a calcium chelating agent.

Priority: US2005-256654 Applic. Date: 2005-10-21; US1998-192609 Applic. Date: 1998-11-16; US1996-719569 Applic. Date: 1996-09-25; US19950004258P Applic. Date: 1995-09-25

Inventor: MONTGOMERY R ERIC [US]


Application No.: US20080131511A1  Published: 05/Jun/2008

Title: Pharmaceutical Composition for Treatment of Tear and Salivary Fluid Drying

Applicant/Assignee: ASTELLAS PHARMA, INC

Application No.: 11/861725   Filing Date: 26/Sep/2007

Abstract:

[Problem] An agent for treating eye and mouth dryness, which does not accompanies undesirable actions is provided. [Means for Resolution] Administration of the compound A made it possible to accelerate tear and salivary fluid secretion without accompanying sweating and its sustained release administration enabled acceleration of lacrimal gland and salivary gland cell growth as well.

Priority: JP20040292611 Applic. Date: 2004-10-05; US2005-578682 Applic. Date: 2005-10-04; WO2005JP18310 Applic. Date: 2005-10-04

Inventor: OKADA YOHEI [JP]; IKEDA KEN [JP]; WANIBUCHI FUMIKAZU [JP]; YOSHIHARA KEIICHI [JP]; KONDO HIROMU [JP]; KOJIMA HIROYUKI [JP]


Application No.: US20080131535A1  Published: 05/Jun/2008

Title: SKIN PROTECTION COMPOSITION

Applicant/Assignee: HOUOUDOU CO., LTD

Application No.: 12/026383   Filing Date: 05/Feb/2008

Abstract:

The present invention provides a method comprising suppressing the growth of a microorganism selected from the group consisting of anthrax bacteria and a virus selected from the group consisting of herpes simplex virus and influenza virus by providing an object containing or impregnated with a composition comprising Sasa extract, and bringing the microorganism into contact with the composition.

Priority: US2005-246194 Applic. Date: 2005-10-11; WO2003JP04635 Applic. Date: 2003-04-11

Inventor: TSUCHIDA YUUZOU [JP]; TSUCHIDA KOTAROU [JP]; TSUCHIDA KENJIROU [JP]; WATANABE KUNITOMO [JP]; NAKAMURA YOSHIKO [JP]; IWASAWA ATSUO [JP]


Application No.: US20080131845A1  Published: 05/Jun/2008

Title: Direct press on veneer

Applicant/Assignee:

Application No.: 11/986636   Filing Date: 24/Nov/2007

Abstract:

A direct resin veneer ( 2 ) for creating a veneer on a tooth surface comprising a thin planar expanse of an uncured restorative material, or direct resin veneer ( 4 ). The veneer ( 4 ) has a generally tooth configuration that is generously sized to permit adequate coverage for any tooth. Adhered to at least one side of the restorative material is a flexible pliant non-sticky planar sheath ( 6 ). The sheath ( 6 ) material has a curved gingival arch contour ( 10 ) for gum line alignment and various tab-like protrusions that permit placement upon a tooth. An inferior peeling tab ( 12 ) allows for sheath to be separated from the resin veneer ( 4 ) subsequent to tooth surface placement. And the lateral grasping tabs ( 16 ) permit delivery to a tooth's surface.

Priority: US20060872464P Applic. Date: 2006-12-02

Inventor: VISCOMI BRIAN D [US]


Application No.: US20080132489A1  Published: 05/Jun/2008

Title: Novel Alkyl Substituted Homopiperazine Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee:

Application No.: 11/795768   Filing Date: 09/Feb/2006

Abstract:

This invention relates to novel alkyl substituted homopiperazine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000197 Applic. Date: 2005-02-10; US20050651217P Applic. Date: 2005-02-10; WO2006EP50785 Applic. Date: 2006-02-09

Inventor: PETERS DAN [SE]; DAHL BJARNE H [DK]; OLSEN GUNNAR M [DK]; NIELSEN ELSEBET OSTERGAARD [DK]; SCHEEL-KRUGER JORGEN [DK]; REDROBE JOHN PAUL [DK]


Application No.: US20080132494A1  Published: 05/Jun/2008

Title: Thiazole and oxazole-substituted arylamides as P2X3 and P2X2/3 antagonists

Applicant/Assignee: ROCHE R&D CENTER CHINA, LTD ROCHE PALO ALTO LLC

Application No.: 11/983225   Filing Date: 08/Nov/2007

Abstract:

Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R<1 >is a group of formula A or formula B, and X, R<2>, R<3>, R<4>, R<5>, R<6>, Rand Rare as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist and methods of making the subject compounds.

Priority: US20060858283P Applic. Date: 2006-11-09

Inventor: DILLON MICHAEL PATRICK [US]; HAWLEY RONALD CHARLES [US]; CHEN LI [CN]; FENG LICHUN [CN]; YANG MINMIN [CN]


Application No.: US20080132509A1  Published: 05/Jun/2008

Title: Substituted Biaryl Analogues

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 11/792984   Filing Date: 13/Dec/2005

Abstract:

Substituted biaryl analogues of Formula (I) are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localizations studies.

Priority: US20040635837P Applic. Date: 2004-12-13; WO2005US45306 Applic. Date: 2005-12-13

Inventor: BLUM CHARLES A [US]; CHENARD BERTRAND L [US]; HODGETTS KEVIN J [US]; ZHENG XIAOZHANG [US]


Application No.: US20080134578A1  Published: 12/Jun/2008

Title: MULTI-BURNER GASIFICATION REACTOR FOR GASIFICATION OF SLURRY OR PULVERIZED HYDROCARBON FEED MATERIALS AND INDUSTRY APPLICATIONS THEREOF

Applicant/Assignee:

Application No.: 11/748844   Filing Date: 15/May/2007

Abstract:

Priority: CN20061119511 Applic. Date: 2006-12-12

Inventor: YU ZUNHONG [CN]; YU GUANGSUO [CN]; GONG XIN [CN]; WANG FUCHEN [CN]; LIU HAIFENG [CN]; DAI ZHENGHUA [CN]; WANG YIFEI [CN]; LI WEIFENG [CN]; LIANG QINFENG [CN]; GUO XIAOLEI [CN]; WANG XINGJUN [CN]; CHEN XUELI [CN]; ZHOU ZHIJIE [CN]


Application No.: US20080135521A1  Published: 12/Jun/2008

Title: Implant surface preparation

Applicant/Assignee:

Application No.: 12/069867   Filing Date: 13/Feb/2008

Abstract:

The surface of a device that is surgically implantable in living bone is prepared. The device is made of titanium with a native oxide layer on the surface. The method of preparation comprises the steps of removing the native oxide layer from the surface of the device and performing further treatment of the surface substantially in the absence of unreacted oxygen.

Priority: US2007-651115 Applic. Date: 2007-01-09; US2005-172775 Applic. Date: 2005-07-01; US2003-701855 Applic. Date: 2003-11-05; US2001-777335 Applic. Date: 2001-02-06; US1999-259432 Applic. Date: 1999-03-01; US1996-607903 Applic. Date: 1996-02-27; US1994-351214 Applic. Date: 1994-11-30

Inventor: BEATY KEITH D [US]


Application No.: US20080138297A1  Published: 12/Jun/2008

Title: Pyran derivatives, process of preparation and use thereof in perfumery and flavouring

Applicant/Assignee: V. MANE FILS

Application No.: 11/948176   Filing Date: 30/Nov/2007

Abstract:

Pyran derivatives of general formula (I) wherein Y is a 5-, 6- or 7-membered ring, preferably a 5-membered ring, methyl or ethyl mono- or polysubstituted, and optionally unsaturated, and R1, R2, R3, R4 are, each independently, a hydrogen atom or a linear or branched C1-5 alkyl or C2-5 alkenyl group, and X is present or absent

when X is present, R5, R6, R7, R8, R9 are all present, and X is a hydrogen atom or an OZ group, wherein Z is a hydrogen atom or a R10 group or a C(O)R10 group

when X is absent, a double bond involving the carbon atom at the 4 position is present and R7, R8 and R9 are present, and one of R5 or R6 is present and the other one is absent, or R5, R6, and R7 are present, and one of R8 or R9 is present and the other one is absent, or R7 is a -C(R11)(R12) group and R5, R6, R8, R9 are present

and when they are present, each of R5-R12 group is, independently, a hydrogen atom or a linear or branched C1-5 alkyl or C2-5 alkenyl group

and use of at least one pyran derivative of formula (I) as flavouring or fragrant agent.

Priority: US20060861966P Applic. Date: 2006-12-01

Inventor: PLESSIS CAROLINE [FR]; MANE JEAN [FR]


Application No.: US20080138298A1  Published: 12/Jun/2008

Title: Oral care compositions comprising zinc and phytate

Applicant/Assignee: THE PROCTER & GAMBLE COMPANY

Application No.: 11/637590   Filing Date: 12/Dec/2006

Abstract:

Disclosed are oral care compositions and their use, comprising in an orally acceptable carrier: (a) from about 0.01 to about 10% by weight of an essentially water-insoluble zinc compound, and (b) from about 0.01% to about 10% by weight of a compound having C-O-P bonds selected from polyphosphorylated inositol compounds such as phytic acid, myo-inositol pentakis(dihydrogen phosphate)

myo-inositol tetrakis(dihydrogen phosphate), myo-inositol trikis(dihydrogen phosphate), and an alkali metal, alkaline earth metal or ammonium salt thereof. The compositions are effective in preventing and controlling oral cavity conditions including plaque, calculus, caries, periodontal disease, mouth malodor and dental erosion and have acceptable aesthetics without the unpleasant astringent and metallic taste associated with the use of zinc.

Priority:

Inventor: GLANDORF WILLIAM MICHAEL [US]; WANG XIAOLI [CN]; SCHWARTZ JAMES ROBERT [US]


Application No.: US20080138299A1  Published: 12/Jun/2008

Title: Oral Pharmaceuticals or Oral Hygiene Products Comprising Licorice Flavonoid Extract

Applicant/Assignee: HAWLEY & HAZEL (BVI) COMPANY LIMITED

Application No.: 11/950386   Filing Date: 04/Dec/2007

Abstract:

The present invention relates to the use of a compound Licochalone A (5-(1,1-Dimethylallyl)-4,4'-dihydroxy-2-methoxychalcone)) as well as Glycyrrhiza inflate Betal flavonoid extract, Glycyrrhiza glabra L. flavonoid extract, Glycyrrhiza kansuensis (Chang et Peng) flavonoid extract, a flavonoid extract of a mixture of two to three of the above licorices, or a mixture of two or three of the above licorice flavonoid extracts, which contains Licochalone A, in inhibiting primary oral pathogenic microorganisms and manufacturing oral care products for countering breath odor, preventing dental caries and reducing dental plaques, reducing gingivitis, tooth desensitizing, anti-calculus, and/or tooth whitening, and relates to oral pharmaceuticals and oral care products thereof.

Priority: CN20061168413 Applic. Date: 2006-12-04

Inventor: SHI YAO [CN]


Application No.: US20080138422A1  Published: 12/Jun/2008

Title: Analgesic Compositions

Applicant/Assignee: PHARMAKODEX LTD

Application No.: 11/883204   Filing Date: 30/Jan/2006

Abstract:

The present invention relates to pharmaceutical compositions comprising an analgesic agent and providing controlled release of the agent for improved treatment and prevention of pain and pain-related conditions, such as pain-related sleep disturbance. The present invention is particularly concerned with self-administered compositions.

Priority: GB20050001809 Applic. Date: 2005-01-28; WO2006GB50025 Applic. Date: 2006-01-30

Inventor: STANIFORTH JOHN [GB]


Application No.: US20080138482A1  Published: 12/Jun/2008

Title: USE OF NEW CAMPHOLENIC DERIVATIVES AS FRAGRANT INGREDIENTS IN PERFUMERY AND FLAVOURING

Applicant/Assignee: V. MANE FILS

Application No.: 11/953157   Filing Date: 10/Dec/2007

Abstract:

This invention relates to campholenic derivatives of general formula (I) Wherein R1, R2, R3, R4 and R5 represent, each independently, a hydrogen atom or a linear or branched C1-C5 alkyl or C2-C5 alkenyl group, Y represents a CN, a C(O)R6 or a CR6(ORalpha) (ORbeta) group, wherein R6 represents a hydrogen atom or a linear or branched C1-C5 alkyl or C2-C5 alkenyl group, and Ralpha and Rbeta represent simultaneously a linear or branched C1, C2, C3, C4 or C5 alkyl or C2, C3, C4 or C5 alkenyl group and can form together a cycle, the 5-membered ring is saturated or has a double bond between C3' and C4' in formula (I), and the side chain, optionally, has a double bond between C1 and C2 and/or between C3 and C4, provided that the derivative is not 3-methyl-6-(2,2,3-trimethyl-cyclopent-3-enyl)-hex-4-enal

and their use as fragrant or flavouring agent.

Priority: US20060873586P Applic. Date: 2006-12-08

Inventor: MANE JEAN [FR]; PLESSIS CAROLINE [FR]; CHANOT JEAN-JACQUES [FR]


Application No.: US20080138770A1  Published: 12/Jun/2008

Title: Light Activated Tooth Whitening Composition and Method of Using Same

Applicant/Assignee: BRITESMILE PROFESSIONAL LLC

Application No.: 11/930025   Filing Date: 30/Oct/2007

Abstract:

The tooth whitening compositions of the present invention include an oxidizing compound and an accelerator. The oxidizing compound and the accelerator may be administered in the same or different composition. The present invention further relates to a method of whitening teeth includes contacting the tooth enamel surface of a patient with composition comprising an oxidizing compound and an accelerator, and, thereafter, exposing the tooth surface to light energy. Alternatively, a method of whitening teeth includes contacting the tooth enamel surface of a patient with an accelerator, then contacting the treated tooth surface with the oxidizing compound, and, thereafter, exposing the tooth surface to light energy.

Priority: US19980074708P Applic. Date: 1998-02-13; US19980075222P Applic. Date: 1998-02-19; US2003-434597 Applic. Date: 2003-05-09; US2000-651170 Applic. Date: 2000-08-30; US1999-234038 Applic. Date: 1999-01-19

Inventor: MONTGOMERY R ERIC [US]


Application No.: US20080139435A1  Published: 12/Jun/2008

Title: Sanitizing Method

Applicant/Assignee: EBIOX, LTD

Application No.: 11/571144   Filing Date: 20/Jun/2005

Abstract:

Ductwork used for the supply of potable water in dental surgeries is prone to undesirable build up of biofilm and associated bacteria. These may be combated effectively by applying to the ductwork a composition comprising: a metal silicate or silicate complex

a metal phosphate or polyphosphate or orthophosphoric acid

and a non-ionic or amphoteric surfactant.

Priority: GB20040013950 Applic. Date: 2004-06-22; WO2005GB02432 Applic. Date: 2005-06-20

Inventor: MACGREGOR KEITH M [GB]


Application No.: US20080139446A1  Published: 12/Jun/2008

Title: Novel Trimethylcyclodoecatriene Derivatives, Use Thereof And Perfumed Products Containing The Same

Applicant/Assignee: V. MANE FILS

Application No.: 11/795382   Filing Date: 13/Jan/2006

Abstract:

The invention relates to a compound of general formula (I) wherein: A) a) R4, R5, and R7 each represent a hydrogen atom and R3, R6 and R8 each represent a methyl radical, or b) R4, R6, and R7 each represent a hydrogen atom and R3, R5 and R8 each represent a methyl radical, or c) R3, R6 and R7 each represent a hydrogen atom and R4, R5 and R8 each represent a methyl radical, and the dotted lines are present and represent cis-double bonds or trans-double bonds, and R1 represents a hydrogen atom and R2 represents an OH, OCH3 or OC2H5 group, or the dotted lines are absent and R1 represents a hydrogen atom and R2 represents an OCH3 group or an OC2H5 group

or B) R1, R4, and R6 each represent a hydrogen atom and R2, R3 and R5 each represent a methyl radical, and the dotted lines are present and represent cis-double bonds or trans-double bonds, and R7 represents a hydrogen atom and R8 represents an OH, OCH3 or OC2H5 bond, or the dotted lines are absent and R7 represents a hydrogen atom and R8 represents an OCH3 group or an OC2H5 group. The inventive compound is an alcoholic derivative or an ether derivative. The invention also relates to the use of at least one compound of formula (I) as an odorant agent.

Priority: FR20050000550 Applic. Date: 2005-01-19; WO2006FR00081 Applic. Date: 2006-01-13

Inventor: MANE JEAN [FR]; CHANOT JEAN-JACQUES [FR]; SCHROEDER MARTIN [GB]


Application No.: US20080139450A1  Published: 12/Jun/2008

Title: Antimicrobial Compositions and Uses Thereof

Applicant/Assignee:

Application No.: 11/750826   Filing Date: 18/May/2007

Abstract:

The present invention includes compositions for preventing growth and proliferation of biofilm embedded microorganisms comprising: (a) a cationic polypeptide and (b) a bis-guanide or a salt thereof. The invention further provides methods for preparing objects with such compositions, and objects and consumables (such as household cleaners) comprising such compositions.

Priority: US2006-331423 Applic. Date: 2006-01-11; US20050742972P Applic. Date: 2005-12-06; US20050695546P Applic. Date: 2005-07-01

Inventor: MADHYASTHA SRINIVASA [CA]; GAWANDE PURUSHOTTAM [CA]; LOVETRI KAREN [CA]


Application No.: US20080139545A1  Published: 12/Jun/2008

Title: FORMULATION TO TREAT EAR INFECTION

Applicant/Assignee:

Application No.: 11/752087   Filing Date: 22/May/2007

Abstract:

The present invention provides a pharmaceutical composition that includes: (a) at least one of a non-aminoglycoside antibiotic and an anti-inflammatory agent

and (b) a biofilm-dissolving agent. The present invention also provides for methods of killing or inhibiting the growth of a fungus by contacting the fungus with a composition of the present invention, methods of killing or inhibiting the growth of a virus by contacting the virus with a composition of the present invention, methods of killing or inhibiting the growth of a bacteria by contacting the bacteria with a composition of the present invention, methods of treating a disorder in a mammal by administering the composition of the present invention to the mammal, methods for preserving contact lens by contacting the contact lens with a composition of the present invention, methods for cleansing surgical or dental instrument by contacting the fungus with a composition of the present invention, and kits that include (a) a container that includes the pharmaceutical composition of the present invention, and (b) a drug delivery device.

Priority: US20060747889P Applic. Date: 2006-05-22

Inventor: CHOE WON-TAEK [US]; ROBERSON JOSEPH BAXTER [US]; MURRAY MICHAEL T [US]


Application No.: US20080139907A1  Published: 12/Jun/2008

Title: Intelligent personal health management appliances for the measurement and monitoring of health factors and controlled delivery of drugs

Applicant/Assignee:

Application No.: 11/018862   Filing Date: 19/Dec/2004

Abstract:

A system, method and apparatus for real time measurement and monitoring of various personal health parameters including controlled delivery of drugs/medications by intelligent pump appliances, intelligent inhalation appliances and intelligent skin patch appliances used in a standalone manner or in a wired or wireless networked configuration, in conjunction with various peripheral devices, other intelligent appliances, servers, RF ID Tags and stationary/mobile devices. The intelligent appliances relate to the measurement, monitoring and delivery of insulin/other drugs for the treatment of diabetes and other diseases. The method also additionally includes the application of intelligent appliances for pain management including visualization of organs and body locations exhibiting pain.

Priority: US2000-680611 Applic. Date: 2000-10-06; US1999-281739 Applic. Date: 1999-06-04; US1996-764903 Applic. Date: 1996-12-16; US2004-001668 Applic. Date: 2004-11-30

Inventor: RAO RAMAN K [US]; RAO SUNIL K [US]; RAO REKHA K [US]


Application No.: US20080140051A1  Published: 12/Jun/2008

Title: HIGHLY TRACKABLE BALLOON CATHETER SYSTEM AND METHOD FOR COLLAPSING AN EXPANDED MEDICAL DEVICE

Applicant/Assignee: GUIDANT ENDOVASCULAR SOLUTIONS

Application No.: 11/608448   Filing Date: 08/Dec/2006

Abstract:

A balloon catheter having a pre-mounted recovery sheath for recovering an expanded device, such as an embolic protection device, in a patient's body lumen, and a method of using a balloon catheter system of the invention to recover the expanded device

Priority: US2006-567682 Applic. Date: 2006-12-06

Inventor: BEI NIANJIONG JOAN [US]; LUBAS JOANNA [US]; MONTANO-MORSE ANA [US]


Application No.: US20080140107A1  Published: 12/Jun/2008

Title: HIGHLY TRACKABLE BALLOON CATHETER SYSTEM AND METHOD FOR COLLAPSING AN EXPANDED MEDICAL DEVICE

Applicant/Assignee: ADVANCED CARDIOVASCULAR SYSTEMS, INC

Application No.: 11/567682   Filing Date: 06/Dec/2006

Abstract:

A balloon catheter having a pre-mounted recovery sheath for recovering an expanded device, such as an embolic protection device, in a patient's body lumen, and a method of using a balloon catheter system of the invention to recover the expanded device

Priority:

Inventor: BEI NIANJIONG JOAN [US]; LUBAS JOANNA [US]; MONTANO-MORSE ANA [US]


Application No.: US20080141476A1  Published: 19/Jun/2008

Title: Oral Care Implement having User-Interactive Display

Applicant/Assignee:

Application No.: 11/610248   Filing Date: 13/Dec/2006

Abstract:

An oral care implement has an interactive display that displays images representing oral care regions of the mouth. The user can interact with the display by playing a game, which can relate to oral care. An oral care implement has a plurality of lighted segments that can be sequentially illuminated to indicate a recommended brushing sequence. The lighted segments can be shaped and/or labeled to indicate particular oral care regions of the mouth.

Priority:

Inventor: GATZEMEYER JOHN J [US]; JIMENEZ EDUARDO J [US]; RIEBE ROBERT [US]; WARD EVAN [US]; FAIR PAUL [US]; MICHAELS JAMES E [US]; CONNOR KEVIN [US]


Application No.: US20080142028A1  Published: 19/Jun/2008

Title: Filtered Cigarette

Applicant/Assignee: R. J. REYNOLDS TOBACCO COMPANY

Application No.: 11/537812   Filing Date: 02/Oct/2006

Abstract:

A filtered cigarette possesses a smokable rod and a filter element. The filter element possesses a segment incorporating filter material (e.g., cellulose acetate tow) having carbonaceous material (e.g., activated charcoal particles) or other adsorbent dispersed throughout the filter material, and encapsulated flavoring agent (e.g., flavor-containing microcapsules) dispersed throughout the filter material.

Priority:

Inventor: FAGG BARRY SMITH [US]


Application No.: US20080142042A1  Published: 19/Jun/2008

Title: AUTOMATED TANK CLEANING AND MONITORING DEVICE

Applicant/Assignee: SPRAYING SYSTEMS CO

Application No.: 11/612979   Filing Date: 19/Dec/2006

Abstract:

A tank cleaning system provides more efficient and more effective tank cleaning than known systems. The tank cleaning system further allows for a cleaning process to be monitored and provides a cleaning validation. In this regard, the tank cleaning system provides control and monitoring of the spray head mechanism while maintaining the mechanical simplicity and robust nature associated with known systems. The tank cleaning system automatically accounts for one or more characteristics of the vessel being cleaned and modifies the cleaning operation accordingly.

Priority:

Inventor: BRAMSEN FRANKLIN ERIK [US]


Application No.: US20080142057A1  Published: 19/Jun/2008

Title: Cleaning device using atmospheric gas discharge plasma

Applicant/Assignee: ATOMIC ENERGY COUNCIL - INSTITUTE OF NUCLEAR RESEARCH ATOMIC ENERGY COUNCIL

Application No.: 11/637869   Filing Date: 13/Dec/2006

Abstract:

Atmospheric gas discharge plasma is generated in a gas whirlpool cavity. Then the plasma is sprayed out in a gas flow to clean an object. The whole process is simple with merits of utility and cost savings. And objects can be cleaned one after one continuously.

Priority:

Inventor: YAN JYH-MING [TW]; CHEN SHIAW-HUEI [TW]; YANG MING-SONG [TW]; HUANG MEN-HAN [TW]; CHEN YUNG-CHIH [TW]


Application No.: US20080142407A1  Published: 19/Jun/2008

Title: Apparatus for and Method of Forming Containers and Container Blank Having Content Retaining Web Attached Thereto

Applicant/Assignee:

Application No.: 11/664069   Filing Date: 27/Sep/2005

Abstract:

A container or container dank ( 100, 200, 300 ) comprises a pair of opposed side wall portions and an opposed front wall portion and rear wall portion, each wall portion being connected to a base portion at a fold line and at least one opposed pair of walls being provided with a lid section. At least one portion has a web of material ( 12, 230, 330 ) adapted to retain an article within a container formed from the blank ( 100, 200, 300 ). Apparatus for and methods of forming a container blank having a web attached thereto and apparatus for and methods of forming a container from a material web lined dank are disclosed with reference to the direction in which the improved tension characteristics of the web are applied. An apparatus and method for filing, closing and sealing an open-mouthed container is also disclosed.

Priority: GB20040021388 Applic. Date: 2004-09-27; WO2004GB04935 Applic. Date: 2004-11-22; WO2005GB03703 Applic. Date: 2005-09-27

Inventor: MOORE ALISTAIR FRASER [GB]


Application No.: US20080143214A1  Published: 19/Jun/2008

Title: SELF-CONTAINED VOLTAGE GENERATING SYSTEMS

Applicant/Assignee: AVON PRODUCTS, INC

Application No.: 11/958633   Filing Date: 18/Dec/2007

Abstract:

A self-contained voltage generating system is incorporated in a package or device for housing a product. There is at least one piezoelectric element incorporated in the package or device and the piezoelectric element generates a source of voltage when it is activated. The voltage is then used to perform various activities on other elements that are part of the package or device, such as operate a motor, provide heat, provide ultrasonic energy, furnish light, provide acoustic energy, and provide vibration energy. The piezoelectric elements are in the form of discrete particles, piezoelectric fibers, filaments, transducers, and actuators.

Priority: US20060875467P Applic. Date: 2006-12-18

Inventor: MCNAMARA WILLIAM E [US]; KUREK JOHN S [US]; LAMBERTY LISA [US]; VOGEL RONALD F [US]; GONZALEZ ANTHONY D [US]; CERUTTI DAVID [US]; ORNOSKI GREGORY A [US]


Application No.: US20080143953A1  Published: 19/Jun/2008

Title: Vapor barrier attachment for eyewear

Applicant/Assignee: KIMBERLY-CLARK WORLDWIDE, INC

Application No.: 11/639940   Filing Date: 15/Dec/2006

Abstract:

A combination includes eyewear, such as glasses, with a removable vapor barrier attachment. The eyewear includes a frame and lenses configured for protecting a user's eyes. The vapor barrier attachment is removably attached to the eyewear, and includes a base member removably attachable to the eyewear frame, and flap members extending from the base member. The flap members have a shape and length so as to extend longitudinally below the eyewear lenses. The flap members are attached to the eyewear along at least a portion of the length of the flap members and have a resilient sealing edge that conforms against the wearer's face to inhibit exhaled air from passing between the lenses and the wearer's face.

Priority:

Inventor: WELCHEL DEBRA [US]; CYR RAYMOND [CA]; BLANCHETTE LUC [CA]


Application No.: US20080145322A1  Published: 19/Jun/2008

Title: Componds, Composition and Method for Controlling Biofolms and Bacterail Infections

Applicant/Assignee: SEQUOIA SCIENCES, INC

Application No.: 11/662806   Filing Date: 14/Sep/2005

Abstract:

The present invention provides compounds and compositions useful for controlling bacterial biofilms as well as for controlling and/or preventing bacterial infections. The compounds of the invention are pentacyclic acid triterpenes. Methods for controlling biofilms and for controlling and/or preventing bacterial infections are also disclosed.

Priority: US20040609763P Applic. Date: 2004-09-14; WO2005US32874 Applic. Date: 2005-09-14

Inventor: ELDRIDGE GARY R [US]


Application No.: US20080145423A1  Published: 19/Jun/2008

Title: Chewable tablet and method of formulating

Applicant/Assignee:

Application No.: 11/639016   Filing Date: 14/Dec/2006

Abstract:

Processes for preparing a chewable tablet comprising a micronized form of an active ingredient, the method comprising the steps of combining the active ingredient with tablet excipients by geometric dilution to form a final mixture and applying direct compression to at least a portion of the final mixture to form at least one tablet.

Priority:

Inventor: KHAN AJMAL ALI [US]; BRUNSON EDDIE [US]


Application No.: US20080145818A1  Published: 19/Jun/2008

Title: Prophylaxis cup having perlite particles, methods of forming and method of use

Applicant/Assignee:

Application No.: 12/008310   Filing Date: 10/Jan/2008

Abstract:

A prophylaxis cup formed of a silicone elastomer having perlite particles incorporated therein as an abrasive material. The silicone elastomer and perlite particles are processed in a 3-roll mill so that the perlite particles have a predetermined size and are uniformly dispersed throughout the prophylaxis cup. As the prophylaxis cup is used to clean and polish teeth, the prophylaxis cup disintegrates upon contact with the teeth releasing the perlite particles which act as a cleaning and polishing agent between the prophylaxis cup and the teeth.

Priority: US2004-877277 Applic. Date: 2004-06-25; US20030482550P Applic. Date: 2003-06-25

Inventor: ECKERT RONALD C [US]


Application No.: US20080145820A1  Published: 19/Jun/2008

Title: METHOD OF MANUFACTURING HIGH STRENGTH DENTAL RESTORATIONS

Applicant/Assignee:

Application No.: 11/946960   Filing Date: 29/Nov/2007

Abstract:

Fiber-reinforced composite posts are produced having high strength and high radiopacity. In a method of manufacturing the fiber-reinforced composite posts, fibers are pulled through filled resin and heat is applied at various steps in the process to provide high strength and optimal radiopacity.

Priority: US2004-839696 Applic. Date: 2004-05-05; US20030468935P Applic. Date: 2003-05-08

Inventor: KARMAKER AJIT [US]; KARLAK MIKE [US]; JIA WEITAO [US]


Application No.: US20080145826A1  Published: 19/Jun/2008

Title: Interactive hygiene training system

Applicant/Assignee:

Application No.: 11/638803   Filing Date: 14/Dec/2006

Abstract:

A method of providing a hygiene system includes providing a dispenser adapted to contain at least one product and deliver a dose of the product when activated

providing at least one applicator adapted to receive the dose of the product and transfer the dose of the product to a target surface

and providing a theme wherein the dispenser is adapted to simulate a first interactive component of the theme and the applicator is adapted to simulate a second interactive component of the theme.

Priority:

Inventor: COHEN JASON C [US]; BECHYNE CHRISTOPHER MICHAEL [US]; JOHNSON ERIC DONALD [US]; KOENIG DAVID WILLIAM [US]; KEHN STEPHEN ROBERT [US]; BOROWSKI KENNETH THOMAS [US]


Application No.: US20080146545A1  Published: 19/Jun/2008

Title: Macrocyclic compounds useful as inhibitors of kinases and HSP90

Applicant/Assignee:

Application No.: 11/891652   Filing Date: 10/Aug/2007

Abstract:

Disclosed are macrocyclic compounds of formulae I-V, which are analogs of the pochonin resorcylic acid lactones, and processes for the preparation of the compounds. The compounds disclosed are useful as inhibitors of kinases and Heat Shock Protein 90 (HSP 90). Also disclosed are pharmaceutical compositions comprising an effective kinase-inhibiting amount or an effective HSP90-inhibiting amount of the compounds and methods for the treatment of disorders that are mediated by kinases and HSP90.

Priority: US20060837154P Applic. Date: 2006-08-11; US20060858731P Applic. Date: 2006-11-13

Inventor: WINSSINGER NICOLAS [FR]; BARLUENGA SOFIA [FR]; KARPLUS MARTIN [US]


Application No.: US20080146611A1  Published: 19/Jun/2008

Title: Compounds for modulating TRPV3 function

Applicant/Assignee: HYDRA BIOSCIENCES INC

Application No.: 11/901253   Filing Date: 14/Sep/2007

Abstract:

The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.

Priority: US20060845039P Applic. Date: 2006-09-15; US20060859139P Applic. Date: 2006-11-15

Inventor: MORAN MAGDALENE M [US]; CHONG JAYHONG A [US]; FANGER CHRISTOPHER [US]; RIPKA AMY [US]; LARSEN GLENN R [US]; ZHEN XIAOGUANG [US]; UNDERWOOD DENNIS JOHN [US]; WEIGELE MANFRED [US]


Application No.: US20080146695A1  Published: 19/Jun/2008

Title: Molding Compositions

Applicant/Assignee:

Application No.: 11/986146   Filing Date: 20/Nov/2007

Abstract:

The present invention relates to molding compositions based on silane-terminated polyether derivatives, to a process for their preparation and to their use.

Priority: DE200610055739 Applic. Date: 2006-11-25

Inventor: NEFZGER HARTMUT [DE]; BAUER ERIKA [DE]; LUDEWIG MICHAEL [DE]; SCHAUB MATTHIAS [DE]; NEHREN KLAUS-DIETER [DE]; FRECKMANN MICHAEL [DE]; URBAS HOLGER [DE]


Application No.: US20080146887A1  Published: 19/Jun/2008

Title: Intelligent personal health management appliances for external and internal visualization of the human anatomy and for dental/personal hygiene

Applicant/Assignee:

Application No.: 11/079917   Filing Date: 13/Mar/2005

Abstract:

A system, method and apparatus for real time visualization of various internal and external parts of the human anatomy, using an intelligent visualization appliance that operates with wired or wireless communication capabilities for communication with one or more other intelligent personal health management appliances, cellular telephone, PDA, lap top computers and other mobile devices, stationary devices and local, central and Internet servers. The intelligent visualization appliance is additionally capable of cleaning various parts of the human body and application of medications. Further including an intelligent dental hygiene system and apparatus for visualization and customized cleaning in conjunction with an intelligent dental hygiene appliance. The intelligent visualization appliance and the intelligent dental hygiene appliance is enabled with internal processing, storage, software, display and other capabilities for standalone operation or operation in conjunction with a mobile device, stationary device and one or more servers in a wired or wireless network.

Priority: US2004-001668 Applic. Date: 2004-11-30

Inventor: RAO RAMAN K [US]; RAO SUNIL K [US]; RAO REKHA K [US]


Application No.: US20080147022A1  Published: 19/Jun/2008

Title: Skin care delivery device having a releasable backing

Applicant/Assignee: KIMBERLY-CLARK WORLDWIDE, INC

Application No.: 11/640432   Filing Date: 15/Dec/2006

Abstract:

A skin care delivery device is disclosed. The skin care delivery device includes a substrate containing a skin care composition. The skin care composition can comprise, for instance, any suitable lotion or other similar material. In accordance with the present disclosure, a backing is releasably engaged to one surface of the substrate. The backing facilitates folding and unfolding of the delivery device. Once applied to a user's skin, the backing can be peeled away and discarded.

Priority:

Inventor: BAUER WALTER G [US]; THOMS CRAIG M [US]; JOHNSON KROY D [US]; FOLEY ED JOHN [US]


Application No.: US20080147104A1  Published: 19/Jun/2008

Title: Oral Care Implement

Applicant/Assignee:

Application No.: 11/612118   Filing Date: 18/Dec/2006

Abstract:

An oral care implement with a soft tissue cleanser is provided to effectively cleanse the soft tissue of the mouth with comfort and a reduced risk of injury to the user. In one construction, a projection is formed of a combination of a hard material and a soft material. The rigid material provides stability for cleaning debris from the tongue or other tissue while the soft material provides comfort and a reduced risk of injury.

Priority:

Inventor: GATZEMEYER JOHN J [US]; HOHLBEIN DOUGLAS J [US]


Application No.: US20080152598A1  Published: 26/Jun/2008

Title: ORAL COMPOSITION FOR STABILIZATION, (RE)CALCIFICATION AND (RE)MINERALIZATION OF TOOTH ENAMEL AND DENTINE

Applicant/Assignee: PRODUCTA LTD

Application No.: 12/042493   Filing Date: 05/Mar/2008

Abstract:

An oral composition for the stabilization, recalcification and remineralization of dental enamel, providing efficient protection from tooth decay. The oral composition uses the calcium form of zeolite, phosphate salts soluble in water, and matrix proteins of teeth. The efficiency of this solution is based on the adjustment of pH in the mouth cavity to the required value while at the same time incorporating the calcium ions from the calcium form of zeolite into the dental enamel and dentin in the presence of matrix proteins of the teeth. Calcium and phosphate ions stabilizes the crystal structure of calcium hydroxyapatite in tooth enamel and dentin.

Priority: HR20030000304 Applic. Date: 2003-04-17; US2005-252353 Applic. Date: 2005-10-17; WO2004HR00010 Applic. Date: 2004-04-15

Inventor: BASIC ROBERT [HR]


Application No.: US20080152600A1  Published: 26/Jun/2008

Title: PEPTIDE-BASED ORAL CARE SURFACE REAGENTS FOR PERSONAL CARE

Applicant/Assignee: E.I. DU PONT DE NEMOURS AND COMPANY

Application No.: 11/971975   Filing Date: 10/Jan/2008

Abstract:

Peptides have been identified that bind to oral surfaces such as teeth and gums. Peptide based oral care reagents have been created by couple such peptides to oral care benefit agents such as whiteners.

Priority: US2005-074473 Applic. Date: 2005-03-08; US2004-935642 Applic. Date: 2004-09-07; US20030501498P Applic. Date: 2003-09-08

Inventor: HUANG XUEYING [US]; O'BRIEN JOHN P [US]; WANG HONG [US]


Application No.: US20080152785A1  Published: 26/Jun/2008

Title: COATED IMPLANTS AND METHODS OF COATING

Applicant/Assignee: CHEMAT TECHNOLOGY, INC

Application No.: 12/043865   Filing Date: 06/Mar/2008

Abstract:

A method including forming a first coating layer derived from an alkoxide on a substrate having a dimension suitable for an implant and forming a second coating layer on the first coating layer that promotes osseointegration. An apparatus comprising a substrate having a dimension suitable as a medical or dental implant and a coating on a surface of a first coating layer derived from an alkoxide and a second coating layer that promotes osseointegration.

Priority: US2006-360144 Applic. Date: 2006-02-22; US2003-454406 Applic. Date: 2003-06-04

Inventor: LIU JIANKAI [US]; HUANG YUHONG [US]; NISHIMURA ICHIRO [US]


Application No.: US20080153054A1  Published: 26/Jun/2008

Title: Shine Guide for Dental Surfaces and Method of Evaluating Shine of a Dental Surface

Applicant/Assignee:

Application No.: 11/615132   Filing Date: 22/Dec/2006

Abstract:

A shine guide is disclosed for use in evaluating dental surfaces. The shine guide includes a substrate having an upper surface

and a plurality of gloss sections arranged on the upper surface of the substrate, wherein each of the plurality of gloss sections has a unique reflectivity measured in gloss units. Also described is a method for evaluating shine of a dental surface and packaging for dentifrices incorporating a shine guide.

Priority:

Inventor: MASTERS JAMES G [US]; CAMPBELL THOMAS S [US]


Application No.: US20080153068A1  Published: 26/Jun/2008

Title: GLASS COMPOSITIONS AS AN ANTIMICROBIAL ADDITIVE FOR DENTAL MATERIALS

Applicant/Assignee: SCHOTT AG

Application No.: 11/548041   Filing Date: 10/Oct/2006

Abstract:

The invention relates to a use of glass compositions having an antimicrobial and/or disinfectant effect in materials used for restoring teeth, excluding implants.

Priority: DE200410026432 Applic. Date: 2004-05-29

Inventor: KESSLER SUSANNE [DE]; FECHNER JORG HINRICH [DE]; SENESCHAL KARINE [DE]; ZIMMER JOSE [DE]


Application No.: US20080153581A1  Published: 26/Jun/2008

Title: Card loading system for a data card unit

Applicant/Assignee: IGT

Application No.: 11/983772   Filing Date: 09/Nov/2007

Abstract:

Disclosed are methods, apparatus, and systems, including computer program products, for transferring data cards between a card loading device and a data card unit of a gaming device. The gaming device has a card mouth adapted to receive and dispense data cards. The card loading device includes a housing, a first card holder adapted to hold one or more data cards having a use designation, and a second card holder adapted to hold one or more data cards having a non-use designation. The card loading device can also include a third card holder adapted to hold one or more of the non-use data cards. The card loading device includes a mating member detachable from the housing. The mating member is adapted to engage the card mouth of the gaming device. The mating member has a mouth adapted to dispense data cards to and receive data cards from the card mouth of the gaming device. The card loading device includes a card transport device operatively coupled to transport the data cards having the use designation from the first card holder to the mouth of the mating member, and to transport the data cards having the non-use designation from the mouth of the mating member to the second card holder. The card loading device includes a data interface configured to communicate with a data interface of the gaming device over a wired or wireless connection.

Priority: US2003-661229 Applic. Date: 2003-09-12; US2005-158478 Applic. Date: 2005-06-22

Inventor: HEDRICK RANDY [US]; CHUDD RUSSELL [US]


Application No.: US20080153912A1  Published: 26/Jun/2008

Title: Compositions and Methods of Their Use for Improving the Condition and Appearance of Skin

Applicant/Assignee: AVON PRODUCTS, INC

Application No.: 12/025133   Filing Date: 04/Feb/2008

Abstract:

The present invention relates to compositions and methods for treating, preventing and improving the condition and/or aesthetic appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, where the compositions include active agents which increase expression levels of genes associated with the dermatological signs of aging. The compositions of the invention are topically applied to the skin, or are delivered by directed means to a site in need thereof, once daily in an amount effective in improving the condition and/or aesthetic appearance of skin.

Priority: US2004-021242 Applic. Date: 2004-12-22

Inventor: DRYER LAURENCE [US]; PTCHELINTSEV DMITRI [US]


Application No.: US20080153913A1  Published: 26/Jun/2008

Title: Nutritional Supplement and Protocol

Applicant/Assignee: MED FIVE, INC

Application No.: 10/571740   Filing Date: 15/Sep/2004

Abstract:

Particular nutritional supplements and protocols emphasize the use of ethylenediamine tetraacetic acid as a mouth rinse, and as an enteric-coated oral pharmaceutical, further supplemented on a daily basis with both a combination of phosphatidyl lipids and alpha lipoic acid and a nutritional supplement containing approximately equal amounts of Reishi and Shiitake mushrooms.

Priority: US20030502993P Applic. Date: 2003-09-15; WO2004US30056 Applic. Date: 2004-09-15

Inventor: COWDEN III RALPH A [US]; KEITH ALEC [US]; ROBERTS JR JAMES C [US]; CRISP WILLIAM E [US]; LAU JANEY A [US]


Application No.: US20080154219A1  Published: 26/Jun/2008

Title: Bodily fluid collection bag kit with externally attached cleansing wipe and breath freshener

Applicant/Assignee:

Application No.: 11/704606   Filing Date: 09/Feb/2007

Abstract:

A bodily fluid collection kit comprising a disposable bag container and a cleansing towelette and breath freshener removably contained at or attached to an outside surface of the bag, that is useful for the collection of bodily fluid and the cleansing and refreshment of the user.

Priority: US20060876622P Applic. Date: 2006-12-21

Inventor: LONGO JEFFERY S [US]; LONGO KIM L [US]


Application No.: US20080154291A1  Published: 26/Jun/2008

Title: Novel Device

Applicant/Assignee:

Application No.: 11/912426   Filing Date: 21/Apr/2005

Abstract:

A tongue cleaning device comprising a tongue cleaning surface supported for tongue cleaning by running the surface across the tongue, a reservoir for a tongue cleaning fluid, means to dispense the fluid either onto the tongue cleaning surface, or directly onto the user's tongue, with a cover part, the tongue cleaning surface and cover part being relatively moveable between a position in which the tongue cleaning surface is exposed for use and a position in which the tongue cleaning surface is covered by the cover part.

Priority: GB20050008374 Applic. Date: 2005-04-25; GB20050015164 Applic. Date: 2005-07-22; GB20060003777 Applic. Date: 2006-02-24; WO2006EP03868 Applic. Date: 2006-04-21

Inventor: BOSMA MARY LYNN [GB]; CHRISP HELEN [GB]; KAY MARTIN [GB]; SAYERS STEPHEN [GB]


Application No.: US20080155770A1  Published: 03/Jul/2008

Title: Power Toothbrush Using Acoustic Wave Action For Cleansing of Teeth

Applicant/Assignee: KONINKLIJKE PHILIPS ELECTRONICS N.V

Application No.: 11/722975   Filing Date: 07/Apr/2005

Abstract:

The toothbrush includes a handle portion and a brushhead assembly which comprises a head portion and a stem portion. The head portion includes a bellows-like acoustic action member for creating acoustic wave action as it moves in and out in response to an acoustic driving force. A drive system is located in the handle and includes an audio speaker-type assembly to create acoustic waves which are transmitted through a transmission line to the acoustic action member. The acoustic action member is driven toward and away from the teeth when the toothbrush is operatively positioned within the mouth. The action of the acoustic member is directly or indirectly coupled to the fluid in the mouth, producing a foam which couples shear forces between the acoustic action member and the teeth/gums to produce a desired cleaning/therapeutic effect.

Priority: US2004-022910 Applic. Date: 2004-12-27; WO2005IB51148 Applic. Date: 2005-04-07

Inventor: GREZ JOSEPH W [US]


Application No.: US20080155771A1  Published: 03/Jul/2008

Title: Tonsil Brush

Applicant/Assignee:

Application No.: 11/745046   Filing Date: 07/May/2007

Abstract:

A device for cleaning tonsils is provided. In one embodiment, the device includes an elongated handle having a longitudinal axis and a head having a longitudinal axis, extending from the elongated handle. The device further includes a first set of projections configured to brush a user's tonsils, disposed on a first surface of the head and extending perpendicular to the longitudinal axis of the head. The device also includes a second set of projections configured to brush a user's tonsils, disposed on a second surface of the head and extending perpendicular to the longitudinal axis of the head.

Priority: US20060882524P Applic. Date: 2006-12-28

Inventor: AGBAJE ISMAILU [US]


Application No.: US20080155985A1  Published: 03/Jul/2008

Title: Heat Energy Recapture And Recycle And Its New Applications

Applicant/Assignee:

Application No.: 11/795835   Filing Date: 27/Jul/2005

Abstract:

A heat absorbing radiator and a gas turbine engine or a reciprocating piston engine are used to recapture and reconvert wasted heat energies into electric power and finally into hydrogen-deuterium fuel by having the engine's tailpipes submerged in cold compressed air inside the heat absorbing radiator pipes in reverse air flow to further drive the same engine. In order to capture fusion heat energy a hydrogen bomb is detonated in deep ocean to catch the flames by the water and the hot water energizes compressed air inside heat absorbing radiator pipes. In order to produce fusion energy an electric arc is passed thru/across liquid or gaseous deuterium by an electro-plasma torch and by a sparkplug in an internal combustion engine, or by detonating a dynamite inside liquid deuterium. Diamond is produced by placing carbon inside a hydrogen bomb which is then detonated in deepwater. Deuterium fusion flame is used first in smelting glass into large structural sizes before running an engine.

Priority: US2005-039624 Applic. Date: 2005-01-20; WO2005US26793 Applic. Date: 2005-07-27

Inventor: LABRADOR GAUDENCIO AQUINO [US]


Application No.: US20080156319A1  Published: 03/Jul/2008

Title: Pulsating Inhaler and a Method of Treating Upper Respiratory Disorders

Applicant/Assignee:

Application No.: 11/916306   Filing Date: 24/May/2006

Abstract:

The present invention discloses a pulsating inhaler, comprising a fluid oscillator providing a focused fluid column with a series of alternating high and low pressures zones

a medicament dispenser adapted for releasing small and constant measures of at least one medicament via said fluid column

and, at least one outlet orifice adapted to direct said focused fluid column towards the respiratory tract of a patient, wherein said small and constant measures of medicament are subjected to the patients while its respiratory tracts are gently and continuously vibrated The present invention also discloses a method of inhaling small and constant measures of medicament while gently and continuously vibrating the patient's respiratory tracks by a means of a fluid column characterized by a series of alternating high and low pressures zones.

Priority: IL20050168975 Applic. Date: 2005-06-02; WO2006IL00611 Applic. Date: 2006-05-24

Inventor: AVNI YUVAL [IL]


Application No.: US20080156674A1  Published: 03/Jul/2008

Title: APPARATUSES AND SYSTEMS FOR STORING, DISPENSING, AND RECONSTITUTING MATERIALS

Applicant/Assignee: PURICORE, INC

Application No.: 11/937352   Filing Date: 08/Nov/2007

Abstract:

The present invention is directed to apparatuses and systems for storing, dispensing, and reconstituting materials. Apparatuses may comprise a container to store a material having an open end and a dispensing aperture. A cover may be configured to seal the open end of the container and a sleeve can include a passageway to slidably receive the container. The container may be moveable within the sleeve between a storing position wherein the dispensing aperture is covered and a dispensing position wherein the dispensing aperture is uncovered to dispense the material. Systems may additionally comprise a reservoir having an opening and the sleeve configured for mounting on the reservoir opening so that when the container is moved to the dispensing position the material is dispensed into the reservoir to form a reconstituted material.

Priority: US20060857785P Applic. Date: 2006-11-09

Inventor: CORREALE DAVID [US]; FISCHER MICHAEL [US]; CLUPPER HAROLD [US]


Application No.: US20080159663A1  Published: 03/Jul/2008

Title: Reclosable bags having slider with finger that stops slider at side seal

Applicant/Assignee:

Application No.: 11/648315   Filing Date: 29/Dec/2006

Abstract:

A reclosable bag comprising a receptacle having a mouth, a flexible closure located near the mouth, and a slider mounted over the mouth. The receptacle comprises first and second panels and first and second seals at respective ends of the mouth. The closure comprises first and second closure profiles. The slider comprises a finger that extends into the mouth, but not between the first and second closure profiles. The slider may be of a type that causes disengaged portions of the first and second closure profiles to mutually engage during travel in either direction. The finger prevents the slider from being pulled off either end of the closure by abutting the corresponding seal. The receptacle and closure may form an airtight boundary for an interior volume.

Priority:

Inventor: PHAM LINH [US]


Application No.: US20080159664A1  Published: 03/Jul/2008

Title: Leakproof zipper end crush for reclosable bag

Applicant/Assignee:

Application No.: 12/075499   Filing Date: 12/Mar/2008

Abstract:

A reclosable bag that can be hermetically sealed. The bag comprises a pair of zipper strips that are joined in respective zones without substantial deformation of the longitudinal profiled closure elements. These zones of zipper strip joinder assist in providing a leakproof transition from the openable section of the zipper to the corner seals, where the longitudinal profiled closure elements are either substantially deformed (e.g., crushed) or absent. The method of manufacture involves the steps of ultrasonically welding a wide area and then thermally crushing a narrower area overlapping the wide welded area to form leakproof zipper joints. This method can be applied to string (flangeless) zippers as well as flanged zippers.

Priority: US2004-895769 Applic. Date: 2004-07-21

Inventor: SHARE LAWRENCE [US]; MATTHEWS DAVID J [US]; CREVIER DONALD L [US]


Application No.: US20080159966A1  Published: 03/Jul/2008

Title: Multiphase Toothpaste Composition

Applicant/Assignee:

Application No.: 11/883674   Filing Date: 06/Jan/2006

Abstract:

Multiphase toothpaste composition comprising a first phase disposed co-axially within a second phase, each of the phases having a viscosity of from 180 000 to 250 000 mPa.s.

Priority: IN2005MU00118 Applic. Date: 2005-02-04; IN2005KO00291 Applic. Date: 2005-04-08; WO2006EP00114 Applic. Date: 2006-01-06

Inventor: AGARWAL RUPESH KUMAR [IN]; FARAVELLI ILARIA [IT]; GREGORY DONALD PETER [GB]; GROVES BRIAN JOSEPH [GB]; WATERFIELD PHILIP CHRISTOPHER [GB]


Application No.: US20080159967A1  Published: 03/Jul/2008

Title: Dentifrices comprising biogenic silica materials and at least one calcium phosphate

Applicant/Assignee:

Application No.: 11/646120   Filing Date: 27/Dec/2006

Abstract:

Unique dentifrices comprising unique abrasive biogenic silica materials are provided. Such compositions exhibit excellent abrasive characteristics, either alone, or in combination with other types of abrasives. In such combinations (with precipitated silica materials, as one example), simultaneously high pellicle film cleaning properties and moderate dentin abrasion levels are possible in order to accord the user a dentifrice that effectively cleans tooth surfaces without detrimentally abrading such surfaces, even at low levels of such biogenic silica additives. Such biogenic silica particles thus surprisingly accord beneficial properties within dentifrice compositions. Encompassed within this invention is the method of utilizing such biogenic silica products within dentifrices, either as the majority abrasive component, or in combination with any other type of commonly used abrasive material.

Priority:

Inventor: FULTZ WILLIAM C [US]; MCGILL PATRICK D [US]


Application No.: US20080159968A1  Published: 03/Jul/2008

Title: Dentifrices comprising biogenic silica materials and calcium carbonate

Applicant/Assignee:

Application No.: 11/646122   Filing Date: 27/Dec/2006

Abstract:

Unique dentifrices comprising unique abrasive biogenic silica materials are provided. Such compositions exhibit excellent abrasive characteristics, either alone, or in combination with other types of abrasives. In such combinations (with precipitated silica materials, as one example), simultaneously high pellicle film cleaning properties and moderate dentin abrasion levels are possible in order to accord the user a dentifrice that effectively cleans tooth surfaces without detrimentally abrading such surfaces, even at low levels of such biogenic silica additives. Such biogenic silica particles thus surprisingly accord beneficial properties within dentifrice compositions. Encompassed within this invention is the method of utilizing such biogenic silica products within dentifrices, either as the majority abrasive component, or in combination with any other type of commonly used abrasive material.

Priority:

Inventor: FULTZ WILLIAM C [US]; MCGILL PATRICK D [US]


Application No.: US20080159977A1  Published: 03/Jul/2008

Title: Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules

Applicant/Assignee:

Application No.: 11/825604   Filing Date: 05/Jul/2007

Abstract:

Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines.

Priority: US2003-658834 Applic. Date: 2003-09-08; US20030457135P Applic. Date: 2003-03-21; US20020409898P Applic. Date: 2002-09-09

Inventor: GANTIER RENE [FR]; VEGA MANUEL [FR]; DRITTANTI LILA [FR]; GUYON THIERRY [FR]


Application No.: US20080160091A1  Published: 03/Jul/2008

Title: COMPOSITE MATERIALS COMPRISED OF CALCIUM COMPOUNDS AND PROTEIN COMPONENTS

Applicant/Assignee: HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN

Application No.: 11/864252   Filing Date: 28/Sep/2007

Abstract:

An oral and dental hygiene product is comprised of a composite material comprising calcium salts which are slightly soluble in water, in the form of nanoparticulate primary particles having a length of from 5 to 150 nm and a cross section of from 2 to 50 nm and protein components selected from the group consisting of proteins, protein hydrolysates and protein hydrolysate derivatives, and 0.1 to 9% by weight of a cleaning agent based on the total weight of the product.

Priority: DE19991030335 Applic. Date: 1999-07-02; US2002-030268 Applic. Date: 2002-03-19; WO2000EP05813 Applic. Date: 2000-06-23

Inventor: KROPF CHRISTIAN [DE]; ROTH MARCEL [DE]; BRUENINGHAUS ULRIKE [DE]; MUELLNER STEFAN [DE]; WEISS ALBRECHT [DE]; SCHOERKEN ULRICH [DE]; KINTRUP LOTHAR [DE]; ESCHEN BURKHARD [DE]; PASTURA AMERIGO [DE]; WUELKNITZ PETER [DE]; KNIEP RUEDIGER [DE]; LASKA HANS [DE]; MEINDERS MICHAEL [DE]; DOLHAINE HANS [DE]


Application No.: US20080160109A1  Published: 03/Jul/2008

Title: Compositions and methods of their use for improving the condition and appearance of skin

Applicant/Assignee: AVON PRODUCTS INC

Application No.: 11/647648   Filing Date: 29/Dec/2006

Abstract:

The present invention relates to compositions and methods for treating, preventing and improving the condition and aesthetic appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, where the compositions include natural plant constituents, or synthetic equivalents thereof, which inhibit or decrease expression of C-reactive protein expression, production or secretion, thereby reducing, inhibiting, or ameliorating dermatological signs of aging. The compositions of the invention may be topically applied to the skin, or are delivered by directed means to a site in need thereof, in an amount effective in improving the condition and aesthetic appearance of skin.

Priority:

Inventor: DRYER LAURENCE [US]; TAFURI SHERRIE R [US]; PTCHELINTSEV DMITRI [US]


Application No.: US20080160138A1  Published: 03/Jul/2008

Title: Confectionery Composition Including an Elastomeric Component, a Cooked Saccharide Component, and a Modified Release Component

Applicant/Assignee: CADBURY ADAMS USA LLC

Application No.: 11/913190   Filing Date: 23/May/2006

Abstract:

The present invention relates to confectionery compositions including cooked saccharide including isomalt, an elastomeric component, and multiple encapsulation component including at least sucralose.

Priority: US20050683634P Applic. Date: 2005-05-23; US20060792556P Applic. Date: 2006-04-17; WO2006US19737 Applic. Date: 2006-05-23

Inventor: BOGHANI NAVROZ [US]; GEBRESELASSIE PETROS [US]; LUO SHIUH JOHN [US]; KABSE KISHOR [US]


Application No.: US20080160193A1  Published: 03/Jul/2008

Title: THIN LAYER SUBSTRATE COATING AND METHOD OF FORMING SAME

Applicant/Assignee: OREGON HEALTH & SCIENCE UNIVERSITY

Application No.: 11/966740   Filing Date: 28/Dec/2007

Abstract:

Embodiments of the present invention relate to coating deposition and coatings for dental and orthopedic devices that provide prevention or reduction of ion leakage and, in some situations, improved aesthetic appearances.

Priority: US20070883302P Applic. Date: 2007-01-03

Inventor: MITCHELL JOHN C [US]


Application No.: US20080162352A1  Published: 03/Jul/2008

Title: Health maintenance system

Applicant/Assignee:

Application No.: 11/649922   Filing Date: 03/Jan/2007

Abstract:

Disclosed is a health maintenance system for comprehensive health assessment, abnormality detection, health monitoring, health pattern and trend detection, health strategy development, and health history archiving. The health maintenance system comprises a subscriber segment and a system segment, communicatively coupled. The subscriber segment acquires subscriber personal and health data from at least one subscriber, analyzing the data

identifies specific health abnormalities

prescribes at least one customized subscriber health product, instructs the subscriber on the implementation of the prescribed health product, compiles and preserves the subscriber's health history data-including abnormalities and prescribed health products, and performs monitoring of subscriber health conditions. The subscriber segment acquires subscriber data from the subscriber segment, stores and maintains the data, facilitates retrieval of data by the subscriber and emergency medical personnel analyzes subscriber patterns and trends, develops new health products and modifies existing health products, and monitors the effectiveness of health products.

Priority:

Inventor: GIZEWSKI THEODORE M [US]


Application No.: US20080163440A1  Published: 10/Jul/2008

Title: Medical instrument pre cleaner

Applicant/Assignee:

Application No.: 11/650603   Filing Date: 08/Jan/2007

Abstract:

A device designed for simplified pre cleaning of instruments used in the medical and dental fields. The device consists of a container housing multiple abrasion elements suspended within the container in close proximity to each other and cleaning fluid. When an instrument is pushed into the abrasion elements it is scrubbed from multiple surfaces, while the cleaning fluid softens and captures debris being removed from the instrument. A motorized version enhances scrubbing action. A lid on the device minimizes the spread of debris around the work station.

Priority:

Inventor: RUELAS ANGELICA DENISE [US]


Application No.: US20080165615A1  Published: 10/Jul/2008

Title: Apparatus and Method for Stirring and Mixing of Beverages

Applicant/Assignee: NESTEC S.A

Application No.: 10/598672   Filing Date: 04/Mar/2005

Abstract:

The present invention relates to drink-stirring device for stirring or mixing liquid and/or powdered ingredients with liquid in a drinking vessel ( 4 ), the liquid being supplied from above through the stirring device to an outlet tube which conducts at least one liquid jet towards the interior of the drinking vessel. The liquid is supplied through an outlet tube ( 64 ) which is rotatably attached to the device and is associated to an external, magnetic member ( 82 ). The electromagnet arrangement is arranged outside or at distance of the magnetic member for creating a variable magnetic field configured to move the tube ( 64 ) in rotation, so that the emerging liquid jet can be given a corresponding centrifugal effect.

Priority: SE20040000618 Applic. Date: 2004-03-10; WO2005EP02301 Applic. Date: 2005-03-04

Inventor: EKLIND EVERT [SE]


Application No.: US20080166303A1  Published: 10/Jul/2008

Title: Colored or colorable foamable composition and foam

Applicant/Assignee:

Application No.: 11/900328   Filing Date: 10/Sep/2007

Abstract:

There is described a colored or colorable topical composition, comprising: a) a foamable base composition comprising, 1) a flowable carrier composition

2) a color agent

wherein the color agent is effective to impart, increase, decrease or otherwise affect color of a foam produced from the foamable composition and wherein the color agent is one or more agents selected from the group consisting of a colored active agent, a colored indicator, a colored excipient, a pigment, a dye, a colorant and a coloring agent

b) a propellant at a concentration of about 3% to about 25% by weight of the total composition

wherein the base composition has a first color

and wherein the foam comprising the colored or colorable topical composition has a second color upon dispensing from an aerosol container, and wherein the first color and the second color are visually different. There is also described a method of changing color, a method of administration, a use as a diagnostic and a kit.

Priority: US20060843144P Applic. Date: 2006-09-08

Inventor: TAMARKIN DOV [IL]; FRIEDMAN DORON [IL]; EINI MEIR [IL]


Application No.: US20080166306A1  Published: 10/Jul/2008

Title: Composition for Mucosally Delivering Fruit Cell Cultures and/or Preparations Derived Therefrom and Methods of Using Same

Applicant/Assignee:

Application No.: 11/884774   Filing Date: 23/Feb/2006

Abstract:

A novel pharmaceutical composition formulated for mucosal delivery for the treatment of inflammatory disorders is disclosed and methods of generating same.

Priority: US20050655918P Applic. Date: 2005-02-25; WO2006IL00249 Applic. Date: 2006-02-23

Inventor: ESHDAT YUVAL [IL]; PERL AVI [IL]


Application No.: US20080166307A1  Published: 10/Jul/2008

Title: Oral Care Compositions Comprising a Hippophae Extract

Applicant/Assignee:

Application No.: 11/621846   Filing Date: 10/Jan/2007

Abstract:

Oral care compositions that comprise a Hippophae extract, as well as methods for reducing inflammation, inhibiting gingivitis, improving oral hygiene and maintaining or increasing systemic health of a mammal, are disclosed.

Priority:

Inventor: FONTANA JOSE EDER [BR]; BETTANI MARCOS ROBERTO [BR]; EMIROVA ALINA [RU]; FERREIRA IEDA [BR]; CORREIA JOAO ABEL [BR]; FOCASSIO PAULO [BR]; VERNILHO DE LIMA EDUARDO CARLO [BR]


Application No.: US20080166394A1  Published: 10/Jul/2008

Title: Food Composition for Binding Acetaldehyde in the Mouth and in Digestive Track and Method for Preparation of the Composition

Applicant/Assignee: BIOHIT OY J

Application No.: 11/910458   Filing Date: 03/Apr/2006

Abstract:

The object of the invention comprises food compositions, to which one or more acetaldehyde-binding compounds are added. The purpose of the compositions is to reduce the amount of detrimental acetaldehyde in the area of the mouth, the pharynx, the oesophagus, the stomach, and the small and large intestines, and through this, to reduce the risk of developing cancers in these areas.

Priority: FI20050000341 Applic. Date: 2005-04-01; WO2006FI00104 Applic. Date: 2006-04-03

Inventor: SUOVANIEMI OSMO [FI]; SALASPURO MIKKO [FI]; SALASPURO VILLE [FI]; MARVOLA MARTTI [FI]


Application No.: US20080166396A1  Published: 10/Jul/2008

Title: Boronate Medicaments Suitable for Short Duration Anticoagulation

Applicant/Assignee: TRIGEN HOLDINGS AG CLAREVILLE HOUSE

Application No.: 10/591962   Filing Date: 09/Mar/2005

Abstract:

An oral dosage form of a compound selected from boronic acids which have a neutral thrombin (P1) domain linked to a hydrophobic moiety capable of binding to the thrombin (S2) and (S3) subsites, and salts, prodrugs and prodrug salts of such acids, the dosage form comprising a solid phase formulation comprising the compound and being adapted for reconstitution of the formulation to form a liquid preparation.

Priority: GB20040005272 Applic. Date: 2004-03-09; WO2005GB00907 Applic. Date: 2005-03-09

Inventor: PATRICK GUY MICHAEL [GB]; COMBE-MARZELLE SOPHIE MARIE [FR]; KENNEDY ANTHONY JAMES [GB]; WITHINGTON ROGER [GB]; BOUCHER OLIVER VIMPANY ARNOLD [BE]


Application No.: US20080166681A1  Published: 10/Jul/2008

Title: Apparatuses for dental implantation and methods for using same

Applicant/Assignee: TACTILE TECHNOLOGIES LLC

Application No.: 12/003935   Filing Date: 03/Jan/2008

Abstract:

A template for performing a dental implantation procedure, comprising: a main body adapted to seat on a plurality of oral structures, and at least one mounting point on the main body for mounting at least one drill guide, wherein the main body is provided with exposed implantation spaces where the dental implantation is to be performed.

Priority: US20070883367P Applic. Date: 2007-01-04

Inventor: WEINSTEIN URIEL [IL]; BERNSTEIN ASSAF [IL]; SHARVIT VERED COHEN [IL]; SHOHAT MICHAL [IL]; YOHAI YUVAL [IL]; GRAF NOA [IL]; ELDAR RONEN [IL]; ZASLAVSKY TATYANA [IL]


Application No.: US20080167334A1  Published: 10/Jul/2008

Title: Compounds for binding to ERalpha/beta and GPR30, methods of treating disease states and conditions mediated through these receptors and identification thereof

Applicant/Assignee:

Application No.: 11/497751   Filing Date: 02/Aug/2006

Abstract:

The current invention is in the field of molecular biology/pharmacology and provides compounds which modulate the effects of GPR30 as well as the classical estrogen receptors alpha and beta (ERalpha and ERbeta). These compounds may function as agonists and/or antagonists of one or more of the disclosed estrogen receptors. Diseases which are mediated through one or more of these receptors include cancer (particularly breast, reproductive and other hormone-dependent cancers, leukemia, colon cancer, prostate cancer), reproductive (genito-urological) including endometritis, prostatitis, polycystic ovarian syndrome, bladder control, hormone-related disorders, hearing disorders, cardiovascular conditions including hot flashes and profuse sweating, hypertension, stroke, obesity, osteoporosis, hematologic diseases, vascular diseases or conditions such as venous thrombosis, atherosclerosis, among numerous others and disorders of the central and peripheral nervous system, including depression, insomnia, anxiety, multiple sclerosis, neuropathy, neurodegenerative disorders such as Parkinson's disease and Alzheimer's disease, as well as inflammatory bowel disease, Crohn's disease, coeliac (celiac)

disease and related disorders of the intestine. A contraceptive indication to prevent or reduce the likelihood of pregnancy after intercourse is a further aspect of the present invention.

Priority: US20050705516P Applic. Date: 2005-08-04

Inventor: PROSSNITZ ERIC R [US]; TKATCHENKO SERGEY E [US]; REVANKAR CHETANA M [US]; SKLAR LARRY A [US]; ARTERBURN JEFFREY B [US]; CIMINO DANIEL F [US]; OPREA TUDOR I [US]; BOLOGA CRISTIAN-GEORGE [US]; EDWARDS BRUCE S [US]; KISELYOV ALEXANDER [US]; YOUNG SUSAN M [US]


Application No.: US20080167376A1  Published: 10/Jul/2008

Title: Methods and products which utilize N-acyl-L-aspartic acid

Applicant/Assignee: DMI BIOSCIENCES, INC

Application No.: 11/966293   Filing Date: 28/Dec/2007

Abstract:

The invention provides therapeutic methods and products for the treatment of inflammation, inflammatory diseases and conditions, and proliferative diseases and conditions. The invention also provides methods and products for inhibiting inflammation in excised cells, tissues and organs. The invention further provides oral care methods and products for the treatment of the tissues of an animal's mouth. Finally, the invention provides personal care methods and products for the treatment of the skin of an animal. All of these methods and products utilize N-acyl-L-aspartic acid or an ester or pharmaceutically-acceptable salt thereof.

Priority: US2004-949715 Applic. Date: 2004-09-24; US20030506323P Applic. Date: 2003-09-25

Inventor: BAR-OR DAVID [US]; RAEL LEONARD T [US]


Application No.: US20080167399A1  Published: 10/Jul/2008

Title: COMPOSITIONS FOR DENTAL COMPOSITES WITH TRICYCLO[5.2.1.02.6]DECANE DERIVATIVES

Applicant/Assignee: HERAEUS KULZER GMBH

Application No.: 11/953120   Filing Date: 10/Dec/2007

Abstract:

Compositions for dental composites comprising monomers, crosslinking agents, fillers, initiators, A the proportion of crosslinking agent being formed in an amount of more than 50% by acrylate monomers with a TCD urethane structure having the general formula in which A, X, Z, R1 R2 R3 and r have the meaning indicated in claim 1, provide polymerized composite materials with a particularly low cytotoxicity according to the standard requirements according to ISO 10993-5 and DIN EN ISO 7405.

Priority: DE200610060983 Applic. Date: 2006-12-20

Inventor: UTTERODT ANDREAS [DE]; RUPPERT KLAUS [DE]; SCHAUB MATTHIAS [DE]; DIEFENBACH CHRISTINE [DE]; REISCHL KURT [DE]; HOHMANN ALFRED [DE]; ECK MICHAEL [DE]; SCHONHOF NELLI [DE]


Application No.: US20080170998A1  Published: 17/Jul/2008

Title: Method and composition for treating or prevending an oral cavity

Applicant/Assignee: CHISSO CORPORATION

Application No.: 12/071770   Filing Date: 26/Feb/2008

Abstract:

The invention relates to a composition for treating or preventing an oral cavity by preventing adhesion of Porphyromonas gingivalis as periodontopathic bacterium to oral tissue. The invention also relates to a composition for treating or preventing an oral cavity containing a peptide in which arginine and histidine bind alternately. Preferably, the invention includes a composition for treating or preventing an oral cavity including the peptide of a pentamer of (arginine-histidine).

Priority: JP20050246639 Applic. Date: 2005-08-26; US2006-509815 Applic. Date: 2006-08-25

Inventor: SHIZUKUISHI SATOSHI [JP]; NAGATA HIDEKI [JP]; HIRAKI JUN [JP]; TODOKORO MASAMI [JP]


Application No.: US20080170999A1  Published: 17/Jul/2008

Title: Thienopyrimidines As Cooling Agents

Applicant/Assignee: CONOPCO, INC

Application No.: 11/791268   Filing Date: 07/Nov/2005

Abstract:

Use of a compound of formula (I) where R<1 >is a C4-6 alkylene linkage optionally substituted by a C1-4alkyl group

R<2 >is -NH, -NH2 or -OH

R<3 >is C1-5 alkyl optionally terminated by a hydroxy, phenyl or a 5- or 6-membered heterocyclic group such as furyl or N-imidazolyl and R<4 >is H

or R<3 >and R<4 >together form a C3-5 alkylene linkage

to produce a topical refreshing or cooling sensation in a mammal such as a human.

Priority: GB20040026266 Applic. Date: 2004-11-30; WO2005EP11972 Applic. Date: 2005-11-07

Inventor: FOSTER ALISON JAYNE [GB]; VAN DE LOGT CORNELIS PAUL ERIK [NL]; LOURBAKOS AFRODITE [NL]; TAREILUS ERWIN WERNER [NL]


Application No.: US20080171001A1  Published: 17/Jul/2008

Title: MINERALIZATION TOOTHPASTE

Applicant/Assignee:

Application No.: 11/972693   Filing Date: 11/Jan/2008

Abstract:

The present invention is directed to a tooth cleaning and mineralizing composition including an abrasive composition in an amount sufficient to provide the tooth cleaning and mineralizing composition with a relative dental abrasion of from 100 to 250

and a stabilized tooth mineralizing mineral composition.

Priority: US20070884738P Applic. Date: 2007-01-12

Inventor: ENGELMAN EMIL E [US]; GAMBOGI ROBERT J [US]; SHARMA DEEPAK [US]


Application No.: US20080171020A1  Published: 17/Jul/2008

Title: Method and composition for repairing epithelial and other cells and tissue

Applicant/Assignee:

Application No.: 11/894150   Filing Date: 20/Aug/2007

Abstract:

The present invention is directed to the expansion, preferably TVEMF-expansion, of mammalian blood adult stem cells, wherein the expansion takes place in a rotating bioreactor, preferably a TVEMF-bioreactor, to compositions resulting from the expanded cells, and to a method of treating an epithelial cell/tissue related disease or condition or repairing tissue of skin, mouth or ear with the compositions.

Priority: US2006-363592 Applic. Date: 2006-02-27; US20050657283P Applic. Date: 2005-02-28; US20050657288P Applic. Date: 2005-02-28; US20050657545P Applic. Date: 2005-02-28

Inventor: RUDD DONNIE [US]


Application No.: US20080171049A1  Published: 17/Jul/2008

Title: Reversible inhibitors of S-adenosyl-L-homocysteine hydrolase and uses thereof

Applicant/Assignee:

Application No.: 11/894364   Filing Date: 20/Aug/2007

Abstract:

The present invention provides compositions and methods for reversibly inhibiting S-adenosyl-L-homocysteine (SAH) hydrolase. The compounds of the present invention can be used in combination with an anti-hemorrhagic viral infection agent, an immunosuppressant, a homocysteine lowering agent, or an anti-neoplasm agent. The compositions and methods of the present invention can be used for the prevention and treatment of hemorrhagic virus infection, autoimmune diseases, autograft rejection, neoplasm, hyperhomocysteineuria, cardiovascular disease, stroke, Alzheimer's disease, or diabetes.

Priority: US2007-649996 Applic. Date: 2007-01-05; US2003-410879 Applic. Date: 2003-04-09

Inventor: YUAN CHONG-SHENG [US]


Application No.: US20080171070A1  Published: 17/Jul/2008

Title: Polyelectrolyte Multilayer Film, Preparation And Uses Thereof

Applicant/Assignee:

Application No.: 11/883375   Filing Date: 31/Jan/2006

Abstract:

The invention relates to polyelectrolyte multilayer films presenting a tunable biological activity and methods for preparing the same. The invention further relates to surfaces presenting such films and uses thereof, such as for the controlled delivery of biologically active agents.

Priority: US20050648279P Applic. Date: 2005-01-31; WO2006IB00378 Applic. Date: 2006-01-31

Inventor: SCHAAF PIERRE [FR]; JESSEL NADIA [FR]; OGIER-DIRRIG JOELLE [FR]; LAVALLE PHILIPPE [FR]; VOEGEL JEAN-CLAUDE [FR]; SENGER BERNARD [FR]


Application No.: US20080171074A1  Published: 17/Jul/2008

Title: Hemostatic Composition, Apparatus, and Methods

Applicant/Assignee:

Application No.: 11/793339   Filing Date: 14/Mar/2008

Abstract:

The present invention provides hemostatic compositions comprising components of the flowers of pharmaceutical chamomile (Chamomilla recutita) and the leaves of dioecious nettle (Urtica dioica). Further inclusion of a biocompatible polymeric base, particularly an alignate, generates a composition with excellent and broad spectrum hemostatic capabilities, with concurrent antiseptic and anti-inflammatory properties. The invention further provides methods of using the inventive compositions in to reduce or stop bleeding, as well as a variety of apparatuses useful in hemostatic contexts that incorporate the inventive compositions. In one particular embodiment, the invention provides hemostatic dressings in which a polymeric layer incorporating chamomile and nettle components is applied to a textile or fabric material, for example a non-woven viscose.

Priority: WO2004IB04355 Applic. Date: 2004-12-20

Inventor: OLTARZHEVSKAYA NATALIE DMITRIE [RU]; SAVILOVA LARISA BORISOVNA [RU]; KRICHEVSKY GERMAN EVSEEVICH [RU]


Application No.: US20080171708A1  Published: 17/Jul/2008

Title: ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS AND METHODS WITH FLAVONOID GLYCOSIDE-TYPE COMPOUNDS

Applicant/Assignee: BMB PATENT HOLDING CORPORATION

Application No.: 11/966795   Filing Date: 28/Dec/2007

Abstract:

The present invention relates to pharmaceutical compositions containing certain flavonoid glycoside-type compounds that have been shown in the present invention to be therapeutically useful, including useful as analgesics and anti-inflammatories for the treatment and management of pain and inflammatory conditions. Methods for the therapeutic uses of such compounds and pharmaceutical compositions is also provided.

Priority: US20060882278P Applic. Date: 2006-12-28

Inventor: BEGOROD BARRY MILES [US]


Application No.: US20080171841A1  Published: 17/Jul/2008

Title: Adhesive For Dental or Surgical Use and Polymerization Initiator Composition For the Same

Applicant/Assignee:

Application No.: 10/585991   Filing Date: 14/Jan/2005

Abstract:

A polymerization initiator composition which does not burn or ignite even when it contacts paper or the like in air and can provide high polymerization activity to a polymerizable composition to cure it in a short period of time, and an adhesive composition comprising the same. The above polymerization initiator composition comprises 100 parts by weight of (A) an organic boron compound such as a trialkyl boron, alkoxyalkyl boron, dialkylborane, monocyclo or bicyclo compound having a boron atom as a hetero atom or partially oxidated trialkyl boron, 5 to 40 parts by weight of (B) an aprotic solvent having a boiling point of 50 to 120 DEG C., and 0.2 to 5 parts by weight of (C) an alcohol having a boiling point of 60 to 180 DEG C.

Priority: JP20040007815 Applic. Date: 2004-01-15; WO2005JP00722 Applic. Date: 2005-01-14

Inventor: ZENG WEIPING [JP]; MUSOU HARUKI [JP]


Application No.: US20080175794A1  Published: 24/Jul/2008

Title: Substituted Pyridazinyl- and Pyrimidinyl-Quinolin-4-Ylamine Analogues

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 11/883005   Filing Date: 25/Jan/2006

Abstract:

Substituted pyridazinyl- and pyrimidinyl-quinolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20050647190P Applic. Date: 2005-01-25; WO2006US02871 Applic. Date: 2006-01-25

Inventor: CALDWELL TIMOTHY M [US]; CHENARD BERTRAND L [US]; HODGETTS KEVIN J [US]


Application No.: US20080175800A1  Published: 24/Jul/2008

Title: USE OF SPECIFIC MENTHYL 3-OXOCARBOXYLIC ACID ESTERS AS PHYSIOLOGICALLY ACTIVE COOLING SUBSTANCES

Applicant/Assignee: SYMRISE GMBH & CO. KG

Application No.: 11/969554   Filing Date: 04/Jan/2008

Abstract:

The use is described of a compound of the formula (I) or (ent-I) or a blend consisting of two, three or more compounds of the formula (I) or (ent-I) (a) as a cooling substance for non-therapeutic purposes or (b) for the production of a medicament, wherein in each of the formulae (I) and (ent-I) R1, R2, R3, R4 and R5 mutually independently in each case mean hydrogen or a linear, branched or cyclic, saturated or unsaturated hydrocarbon residue having 1 to 4 carbon atoms.

Priority: US20070883400P Applic. Date: 2007-01-04

Inventor: SCHOENING AXEL [DE]; WIEDWALD BERND [DE]


Application No.: US20080175801A1  Published: 24/Jul/2008

Title: Stable peroxide containing personal care compositions

Applicant/Assignee: THE PROCTER & GAMBLE COMPANY

Application No.: 11/654837   Filing Date: 18/Jan/2007

Abstract:

The present invention relates to stable personal care composition, including oral care compositions containing a peroxide source. The compositions are stabilized by eliminating or minimizing the presence in the composition of metals having radical forming potential with the peroxide. Preferably, the metals that are eliminated or reduced are cobalt, copper, palladium, nickel and iron. The compositions are further stabilized by the addition of agents having scavenging or quenching activity for free radicals. Reducing free radical activity in the product matrix prevents radical-mediated loss and degradation of peroxide and other ingredients, in particular organic compounds added as active or aesthetic agents, including flavors, perfumes, colorants and thickeners. Provided are peroxide containing oral care products with enhanced consumer appeal in terms of taste, mouthfeel and appearance, thereby encouraging compliance and regular use. Such attributes are important since use of these products may involve fairly long residence time in the mouth for efficacy.

Priority:

Inventor: RAMJI NIRANJAN [US]


Application No.: US20080175925A1  Published: 24/Jul/2008

Title: Method and composition for the treatment of herpes virus

Applicant/Assignee:

Application No.: 12/009597   Filing Date: 19/Jan/2008

Abstract:

A composition and method for oral application to mouth tissue to reduce the symptoms of herpes simplex virus infection, said composition comprising an anti-viral agent, an antioxidant agent, an analgesic agent and a flavorant.

Priority: US20070897019P Applic. Date: 2007-01-23

Inventor: OXFORD J CRAIG [US]


Application No.: US20080176189A1  Published: 24/Jul/2008

Title: Dental demonstration template and matching temporary overlay

Applicant/Assignee:

Application No.: 12/079386   Filing Date: 26/Mar/2008

Abstract:

A dental prosthesis or template ( 10 ) simulates the front surfaces of a patient's teeth and is positioned to overlay over a patient's natural teeth ( 40 ) to provide an indication of what a dental porcelain overlay may look like once applied to the patient's teeth. A matching temporary veneer overlay ( 110 ) with simulated matching teeth sized and shaped to the template is constructed to be installed over the patient's prepared teeth.

Priority: US2005-226113 Applic. Date: 2005-09-14; US2005-096602 Applic. Date: 2005-04-01

Inventor: STONISCH MARY SUE [US]


Application No.: US20080176468A1  Published: 24/Jul/2008

Title: Selectively permeable protective structure and articles therefrom

Applicant/Assignee: E. I. DU PONT DE NEMOURS AND COMPANY

Application No.: 11/506731   Filing Date: 18/Aug/2006

Abstract:

An article comprising a selectively permeable membrane supported on a support is disclosed wherein the article has moisture vapor transmission rate of at least 1800 g/m<2>/24 h and the selectively permeable membrane comprises a composition comprising an organic acid-modified ionomer.

Priority:

Inventor: CHEN JOHN CHU [US]


Application No.: US20080176783A1  Published: 24/Jul/2008

Title: Production of Peracids Using An Enzyme Having Perhydrolysis Activity

Applicant/Assignee:

Application No.: 11/743354   Filing Date: 02/May/2007

Abstract:

A process is provided for producing peroxycarboxylic acids from carboxylic acid esters. More specifically, carboxylic acid esters are reacted with an inorganic peroxide, such as hydrogen peroxide, in the presence of an enzyme catalyst having perhydrolysis activity. The present perhydrolase catalysts are classified as members of the carbohydrate esterase family 7 (CE-7) based on the conserved structural features. Further, disinfectant formulations comprising the peracids produced by the processes described herein are provided.

Priority: US2006-638635 Applic. Date: 2006-12-12; US20050750092P Applic. Date: 2005-12-13; US20060853065P Applic. Date: 2006-10-20

Inventor: DICOSIMO ROBERT [US]; GAVAGAN JOHN E [US]; PAYNE MARK S [US]; COOLING FREDERICK B [US]


Application No.: US20080176805A1  Published: 24/Jul/2008

Title: Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells

Applicant/Assignee:

Application No.: 11/680119   Filing Date: 28/Feb/2007

Abstract:

The embodiments include methods of treating conditions requiring removal or destruction of cellular elements, such as benign or malignant tumors in humans, using compounds based on small peptides. The method includes, but is not limited to, administering the compounds intramuscularly, orally, intravenously, intrathecally, intratumorally, intranasally, topically, transdermally, etc., either alone or conjugated to a carrier.

Priority: US20060776933P Applic. Date: 2006-02-28

Inventor: AVERBACK PAUL [CA]; GEMMELL JACK [CA]


Application No.: US20080176843A1  Published: 24/Jul/2008

Title: Modulators of muscarinic receptors

Applicant/Assignee: VERTEX PHARMACEUTICALS INCORPORATED

Application No.: 11/893245   Filing Date: 15/Aug/2007

Abstract:

The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

Priority: US20060837786P Applic. Date: 2006-08-15

Inventor: MAKINGS LEWIS R [US]; HURLEY DENNIS J [US]; RAFFAI GABRIEL [US]


Application No.: US20080176856A1  Published: 24/Jul/2008

Title: Novel Alkyl Substituted Piperidine Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee:

Application No.: 11/579116   Filing Date: 14/Jun/2005

Abstract:

This invention relates to novel alkyl substituted piperazine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20040000959 Applic. Date: 2004-06-18; US20040581363P Applic. Date: 2004-06-22; WO2005EP52732 Applic. Date: 2005-06-14

Inventor: PETERS DAN [DK]; OLSEN GUNNAR M [DK]; NIELSEN ELSEBET OSTERGAARD [DK]; SCHEEL-KRUGER JORGEN [DK]


Application No.: US20080176955A1  Published: 24/Jul/2008

Title: COMBINED ADMINISTRATION OF BENZONATATE AND GUAIFENESIN

Applicant/Assignee: VICTORY PHARMA, INC

Application No.: 12/015413   Filing Date: 16/Jan/2008

Abstract:

Pharmaceutical compositions are provided containing a combination of benzonatate and guaifenesin, or pharmaceutically acceptable salts thereof. Methods of using compositions comprising benzonatate and guaifenesin, or pharmaceutically acceptable salts thereof, provide relief from cough, pulmonary congestion or both. The compositions and methods provide relief to opiate-sensitive individuals, in particular, as well as to infants and other pediatric patients.

Priority: US20070885154P Applic. Date: 2007-01-16

Inventor: HECK THOMAS [US]; CVIJANOVICH MICHAEL [US]


Application No.: US20080177217A1  Published: 24/Jul/2008

Title: Taurolidine Formulations and Delivery: Therapeutic Treatments and Antimicrobial Protection Against Bacterial Biofilm Formation

Applicant/Assignee:

Application No.: 11/596525   Filing Date: 16/May/2005

Abstract:

Treating of localized bacterial infection, comprising locally applying Taurolidine to the infection. A device for insertion into the body, the device comprising Taurolidine to render the device infection resistant. A medication for treating bacterial infections, comprising Taurolidine carried by one of: gels, liquid, thixotropic gels, colloidal mixtures, dispensal suspensions, injectable polymers, or a microparticle. A method for treating blood, comprising: removing blood from the body

treating the blood with Taurolidine

and returning the treated blood.

Priority: US20040571272P Applic. Date: 2004-05-14; WO2005EP05438 Applic. Date: 2005-05-16

Inventor: POLASCHEGG HANS-DIETRICH [AT]


Application No.: US20080178558A1  Published: 31/Jul/2008

Title: Machine For Filling Sealed Soft Containers in an Aseptic Environment, and Method For Their Filling

Applicant/Assignee: F B R- ELPO-SOCIETA' PER AZIONI FBR-ELPO-SOCIETA PER AZIONI

Application No.: 11/910114   Filing Date: 30/Mar/2005

Abstract:

The method consists of filling a soft container ( 2 ) comprising two thin sheets sealedly joined together along a bounding perimeter by the following steps: providing an internally sterile container ( 2 ), inserting a nozzle ( 8 ) with a delivery mouth ( 9 ) through an aperture ( 5 ) formed in the container ( 2 ), conveying the fluid material into the container through said mouth ( 9 ), extracting the nozzle ( 8 ) from the container ( 2 ) after conveying the material

closing said aperture ( 5 ) by sealing the two sheets of the container ( 2 ). The filling machine comprises: a sealing box ( 3 ) comprising two complementary half-boxes ( 4 a , 4 b)

clamping means for clamping together and unclamping said two half-boxes ( 4 a , 4 b) along respective sealing edges ( 21, 22, 23 ), to isolate its interior from the outside environment

aperture-forming means ( 26 a , 26 b , 26 c) located in said sealing box ( 3 ) to form an aperture ( 5 ) in that portion of the container ( 2 ) inserted in the box ( 3 )

filling means ( 8, 9 ) for filling the container ( 2 ) through the aperture ( 5 )

welding means ( 32 ) for sealing said aperture ( 5 ) on termination of filling.

Priority: WO2005EP03490 Applic. Date: 2005-03-30

Inventor: MERUSI PIER LUIGI [IT]


Application No.: US20080178904A1  Published: 31/Jul/2008

Title: Toothpick device

Applicant/Assignee:

Application No.: 11/699239   Filing Date: 29/Jan/2007

Abstract:

A toothpick device for cleaning teeth includes a toothpick. The toothpick is comprised of two separable portions and has at least one pointed end. A length of dental floss is provided with each end of the dental floss being secured to one of the two portions of the toothpick by melted wax. The dental floss is wound for storage between said two portions whereby separating the two portions unwinds the dental floss for use.

Priority:

Inventor: PETERS CASSIE [US]


Application No.: US20080179785A1  Published: 31/Jul/2008

Title: Process and Mold for Thermoforming Containers

Applicant/Assignee:

Application No.: 12/021637   Filing Date: 29/Jan/2008

Abstract:

Methods of manufacturing water-soluble containers using a horizontal intermittent motion thermoforming machine which comprises the steps of: a) locating a first water-soluble film over a mould, said mould containing a plurality of pocket forming cavities, defined by side walls and a base, in a 2-dimensional array, each cavity being surrounded by a planar surface of the mould on all sides in which the shortest dimension of the planar surface between two adjacent cavities is at least 3 mm and between an edge of the mould and the closest cavity is at least 1.5 mm

b) thermoforming the first film to produce a plurality of pockets

c) at least partially filling the pockets with a composition

and d) sealing the plurality of the at least partially filled pockets. The cavities are positioned in the array such that there are a plurality of continuous strips of uninterrupted planar surface of the mould from a leading to a trailing edge of the mould, for receiving support means fitted to the machine for supporting the film.

Priority: GB20000020964 Applic. Date: 2000-08-25; US2004-362615 Applic. Date: 2004-11-29

Inventor: HAMMOND GEOFFREY ROBERT [GB]; ROGERS RICHARD [GB]


Application No.: US20080181855A1  Published: 31/Jul/2008

Title: Tooth whitener and maintenance with bleach bumpers

Applicant/Assignee:

Application No.: 11/985944   Filing Date: 19/Nov/2007

Abstract:

A tooth whitening and maintenance system and method and a system and method for protecting the gums.

Priority: US20060859644P Applic. Date: 2006-11-17; US20070994866P Applic. Date: 2007-09-21

Inventor: JABLOW JENNIFER [US]


Application No.: US20080181876A1  Published: 31/Jul/2008

Title: Methods for treating acute and subchronic pain

Applicant/Assignee:

Application No.: 12/011997   Filing Date: 29/Jan/2008

Abstract:

Methods of potentiating opioid-induced analgesia in a subject by administration of a phosphodiesterase (PDE) inhibitor or glial attenuator are described. In particular, the present invention is directed to methods of treating or preventing acute or subchronic pain by administration of a PDE inhibitor or glial attenuator, such as ibudilast (3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine), in combination with an opioid.

Priority: US20070898362P Applic. Date: 2007-01-30

Inventor: JOHNSON KIRK W [US]; WATKINS LINDA R [US]; HUTCHINSON MARK [US]


Application No.: US20080181923A1  Published: 31/Jul/2008

Title: INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES

Applicant/Assignee: NORTH CAROLINA STATE UNIVERSITY

Application No.: 12/020112   Filing Date: 25/Jan/2008

Abstract:

Disclosure is provided for imidazole derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same.

Priority: US20070886789P Applic. Date: 2007-01-26

Inventor: MELANDER CHRISTIAN [US]; CAVANAGH JOHN [US]; HUIGENS ROBERT W [US]; BALLARD T ERIC [US]; RICHARDS JUSTIN J [US]


Application No.: US20080181925A1  Published: 31/Jul/2008

Title: Compositions and Methods for Enzymatic Detachment of Bacterial and Fungal Biofilms

Applicant/Assignee: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY

Application No.: 11/938617   Filing Date: 12/Nov/2007

Abstract:

Isolated nucleic acid sequences and amino acid sequences for soluble, beta-N-acetylglucosaminidase or active fragments or variants thereof which promote detachment of bacterial cells from a biofilm are provided. An isolated mutant bacteria which forms biofilm colonies which tightly adhere to surface but which are unable to release cells into the medium or spread over the surface is also provided. In additions, methods are described for modulating detachment of bacterial cells from biofilm by mutating soluble, beta-N-acetylglucosaminidase or altering its expression or activity are also provided. Also provided are compositions, methods and devices for preventing, inhibiting and treating bacterial infections.

Priority: US2003-538902 Applic. Date: 2003-10-31; WO2003US34683 Applic. Date: 2003-10-31; US20020435817P Applic. Date: 2002-12-20

Inventor: KAPLAN JEFFREY B [US]


Application No.: US20080181934A1  Published: 31/Jul/2008

Title: NOVEL ENHANCED MEDICINAL DELIVERY SYSTEM PROCESSES AND PRODUCTS THEREBY ESPECIALLY USEFUL FOR CHILDREN

Applicant/Assignee:

Application No.: 11/933003   Filing Date: 31/Oct/2007

Abstract:

Pharmacologically effective amounts of a medication are delivered in pleasant tasting delivery vehicles, including gelatins and candies. Mechanisms for the reduction in surface area of noxious taste-imparting aspects of conventional medicines, and dilutive effects of positive masking elements for such medicines, especially products for inducing children to take medicines, are taught-in combination with processes and products thereby.

Priority: US20070886913P Applic. Date: 2007-01-26

Inventor: CHOW MICHELLE [US]


Application No.: US20080182218A1  Published: 31/Jul/2008

Title: Release agent receptacle

Applicant/Assignee:

Application No.: 12/011942   Filing Date: 29/Jan/2008

Abstract:

The present disclosure includes method, system, apparatus, and indicator embodiments. One apparatus includes an appliance for placement over one or more teeth and a release agent receptacle including an outer portion provided on appliance surface, an inner portion provided within the outer portion, and one or more apertures formed in the outer portion.

Priority: US2007-799979 Applic. Date: 2007-05-03; US2004-949717 Applic. Date: 2004-09-24

Inventor: CHEN JENNIFER C [US]; SU LI-HUNG [US]; LI CHUNHUA [US]


Application No.: US20080182919A1  Published: 31/Jul/2008

Title: Dental Restorative Composition

Applicant/Assignee: SUN MEDICAL CO., LTD

Application No.: 11/884131   Filing Date: 09/Feb/2006

Abstract:

A dental restorative composition comprising a polymerizable monomer having at least 3 partial chains which are polyester chains bonded to polymerizable groups in one molecule. The dental restorative composition having high mechanical properties, especially high tenacity and excellent impact resistance and fracture resistance as a resin prosthetic material such as a resin for dental crows and artificial teeth, a filler material such as a composite resin, or other resin-based dental material is provided.

Priority: JP20050035024 Applic. Date: 2005-02-10; WO2006JP02679 Applic. Date: 2006-02-09

Inventor: SAIMI YASUKAZU [JP]; IMAI HIROFUMI [JP]


Application No.: US20080182948A1  Published: 31/Jul/2008

Title: Low shrinkage and low stress dental compositions

Applicant/Assignee:

Application No.: 12/079987   Filing Date: 31/Mar/2008

Abstract:

A composition of macrocyclic oligomer with at least one polymerizable group, (meth)acrylate, for example.

Priority: US2005-153089 Applic. Date: 2005-06-15; US20040579837P Applic. Date: 2004-06-15

Inventor: JIN XIAOMING [US]; HAMMESFAHR PAUL D [US]


Application No.: US20080182997A1  Published: 31/Jul/2008

Title: Radical polymerizable macrocyclic resin compositions with low polymerization stress

Applicant/Assignee: DENTSPLY INTERNATIONAL INC

Application No.: 12/079525   Filing Date: 27/Mar/2008

Abstract:

A composition of macrocyclic oligomer with at least one (meth)acrylate polymerizable group. A method includes preparing an activated precursor of an oligomer at pseudo high-dilution conditions. A method also includes preparing an activated precursor of an oligomer by reacting the precursor with an activated coupling agent, wherein the precursor is condensable and polymerizable.

Priority: US2005-153090 Applic. Date: 2005-06-15; US20040579836P Applic. Date: 2004-06-15

Inventor: JIN XIAOMING [US]; HAMMESFAHR PAUL D [US]


Application No.: US20080183101A1  Published: 31/Jul/2008

Title: Salivary analysis

Applicant/Assignee:

Application No.: 11/891953   Filing Date: 14/Aug/2007

Abstract:

The present invention relates to the multivariate analysis of spectra from saliva for estimating the oral health of an individual or group of individuals. The technique enables rapid sampling and evaluation and is particularly useful for facilitating the screening and monitoring of participants in clinical trials, and for evaluating developmental treatment products, as well as providing a straightforward, non-invasive diagnostic method.

Priority: US20060838221P Applic. Date: 2006-08-17

Inventor: STONEHOUSE JONATHAN RICHARD [GB]; DAVISON GORDON ROBERT [GB]; WHITE DONALD JAMES [US]; BATTAINI GIUSEPPE [DE]; CANNON MICHAEL JAMES [GB]


Application No.: US20080183129A1  Published: 31/Jul/2008

Title: Method for vascular occlusive therapy in gastrointestinal system

Applicant/Assignee: SCIMED LIFE SYSTEMS, INC

Application No.: 11/880646   Filing Date: 23/Jul/2007

Abstract:

A method for treating a blood vessel in a wall forming a gastrointestinal tract of a body of a mammal. An occlusion is formed in the vessel so as to terminate blood flow to the vessel distal of the occlusion. A method for treating a varix in a gastrointestinal wall, a method of treating an ulcer in a gastrointestinal wall, and a method for treating a hemorrhoid in a rectal wall are also provided.

Priority: US2003-384285 Applic. Date: 2003-03-06; US2001-853060 Applic. Date: 2001-05-10; US1999-412105 Applic. Date: 1999-10-04; US1999-232056 Applic. Date: 1999-01-15; US19980111884P Applic. Date: 1998-12-11

Inventor: SILVERMAN DAVID E [US]; STEIN ALAN [US]


Application No.: US20080185016A1  Published: 07/Aug/2008

Title: DENTAL FLOSSER WITH TONGUE CLEANER

Applicant/Assignee:

Application No.: 11/671561   Filing Date: 06/Feb/2007

Abstract:

A dental flosser having a tongue cleaner, the flosser including a handle terminating at a head: a pair of spaced apart arms extending from the head, a length of dental floss extending between the arms

and a rugous surface on at least one of the arms suitable for being scraped against the tongue of a user for effectively cleaning the tongue.

Priority:

Inventor: JANSHESKI JOHN M [US]; SHANKLE LEX [US]


Application No.: US20080187497A1  Published: 07/Aug/2008

Title: Toothpaste

Applicant/Assignee:

Application No.: 11/883677   Filing Date: 12/Jan/2006

Abstract:

A toothpaste which comprises first and second compositions, the first and second compositions comprising water, humectant and thickener and the second composition disposed coaxially within the first composition, the first composition being a gel and the second composition being opaque, the second composition comprising an opacifier at y % by weight of the second composition and the first composition comprising 0.2 to 2.0y % by weight of the first composition more thickener than is present as a weight percent of the second composition.

Priority: IN2005MU00118 Applic. Date: 2005-02-04; IN2005KO00293 Applic. Date: 2005-04-08; WO2006EP00236 Applic. Date: 2006-01-12

Inventor: AGARWAL RUPESH KUMAR [IN]; FARAVELLI ILARIA [IT]; GREGORY DONALD PETER [GB]; GROVES BRIAN JOSEPH [GB]; ROBERTS GERAINT PAUL [GB]


Application No.: US20080187498A1  Published: 07/Aug/2008

Title: Multiphase Toothpaste Composition

Applicant/Assignee:

Application No.: 11/883678   Filing Date: 16/Jan/2006

Abstract:

Multiphase toothpaste composition comprising a first phase disposed co-axially within a second phase, each of the phases having a specific gravity of from 1.1 to 1.5 g/ml.

Priority: IN2005MU00118 Applic. Date: 2005-02-04; IN2005KO00290 Applic. Date: 2005-04-08; WO2006EP00337 Applic. Date: 2006-01-16

Inventor: FRANCIS EDWARD [IN]


Application No.: US20080187500A1  Published: 07/Aug/2008

Title: HYBRID ORGANIC/INORGANIC CHEMICAL HYBRID SYSTEMS, INCLUDING FUNCTIONALIZED CALCIUM PHOSPHATE HYBRID SYSTEMS, AND A SOLID-STATE METHOD FOR PRODUCING THE SAME

Applicant/Assignee:

Application No.: 12/018627   Filing Date: 23/Jan/2008

Abstract:

A solid-state method of producing functionalized moieties, including placing predetermined amounts of inorganic and inorganic materials and milling media into a vessel rotatably connected to a turntable platform, an amount of an organic material into the vessel, rotating the vessel in a first direction while turning the turntable platform in a second direction counter to the first direction, milling the inorganic and organic materials into smaller respective organic and inorganic particles, and fusing portions of organic particles to inorganic parties to define functionalized moieties. The inorganic material may include calcium phosphates of varying phases, structure, and composition. The organic material may include anionic surfactants, cationic surfactants, neutral surfactants, carboxylic acids, polymers, copolymers, block copolymers, and combinations thereof.

Priority: US20070888354P Applic. Date: 2007-02-06; US20070891849P Applic. Date: 2007-02-27; US20070941095P Applic. Date: 2007-05-31

Inventor: KARLINSEY ROBERT L [US]


Application No.: US20080187501A1  Published: 07/Aug/2008

Title: Oral Composition Containing Oxidized Camellia

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/098802   Filing Date: 07/Apr/2008

Abstract:

Oral composition comprising a Camellia extract of semi-oxidized tissue from a member of the genus Camellia and an enhancing agent.

Priority: US2005-256776 Applic. Date: 2005-10-24; US20040639169P Applic. Date: 2004-12-23

Inventor: BOYD THOMAS J [US]; GAFFAR ABDUL [US]; VISCIO DAVID [US]


Application No.: US20080187513A1  Published: 07/Aug/2008

Title: Treatment of Solid Cancers

Applicant/Assignee: PEPLIN RESEARCH PTY LTD

Application No.: 11/792264   Filing Date: 02/Dec/2005

Abstract:

The present invention relates generally to the field of cancer including tumor therapy. More particularly, the present invention relates to the treatment of solid cancers, including solid tumors, and the prevention or reduction of cancer metastasis, by chemoablation of cancer cells by an agent which also stimulates the generation of cancer-specific T-cells, a process referred to herein as immunostimulatory chemoablation. The present invention further contemplates combination therapy comprising immunostimulatory chemoablation and one or more other therapeutic regimens, which enhance, co-operate and/or synergize with the cancer-specific T-cells induced by the chemoablation. The present invention also relates to pharmaceutical compositions for use in treating cancers.

Priority: AU20040907105 Applic. Date: 2004-12-13; WO2005AU01827 Applic. Date: 2005-12-02

Inventor: OGBOURNE STEVEN MARTIN [AU]; SUHRBIER ANDREAS [AU]


Application No.: US20080187518A1  Published: 07/Aug/2008

Title: Production of Osteoclasts from Adipose Tissues

Applicant/Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION

Application No.: 11/915032   Filing Date: 25/May/2006

Abstract:

The present invention provides methods for growing and inducing osteoclastic differentiation of adipose tissue derived cells. The present invention further provides methods for administering such adipose tissue derived cells to a subject. The present invention further provides methods for treating diseases, disorders, and conditions associated with aberrant regulation or numbers of osteoclasts.

Priority: US20050684599P Applic. Date: 2005-05-25; WO2006US20535 Applic. Date: 2006-05-25

Inventor: OGLE ROY CLINTON [US]; THOLPADY ASHOK [US]; THOLPADY SUNIL SHANTIGODU [US]


Application No.: US20080187528A1  Published: 07/Aug/2008

Title: ANTI-TSG101 ANTIBODIES AND THEIR USES FOR TREATMENT OF VIRAL INFECTIONS

Applicant/Assignee: FUNCTIONAL GENETICS, INC

Application No.: 11/940714   Filing Date: 15/Nov/2007

Abstract:

The present invention provides antibodies that bind to the C-terminal region of TSG101. The invention also provides methods of using the TSG101 antibodies for the treatment of viral infections, including HIV and Ebola virus infection.

Priority: US20060858922P Applic. Date: 2006-11-15

Inventor: LI LIMIN [US]; KINCH MICHAEL [US]; GOLDBLATT MICHAEL [US]


Application No.: US20080187575A1  Published: 07/Aug/2008

Title: Pyrimidine Derivatives

Applicant/Assignee:

Application No.: 11/661041   Filing Date: 29/Aug/2005

Abstract:

The present invention relates to pyrimidine derivatives, methods for their synthesis, and the use of said pyrimidine derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of cell proliferation disorders, cancer, leukemia, erectile dysfunction, cardiovascular diseases and disorders, inflammatory diseases, transplant rejection, immunological diseases, neuroimmunological diseases, autoimmune diseases, infective diseases including opportunistic infections, prion diseases and/or neuro-degeneration. Furthermore, the present invention relates to pharmaceutical compositions containing at least one pyrimidine derivative and/or pharmaceutically acceptable salts thereof as an active ingredient together with at least one pharmaceutically acceptable carrier, excipient or diluents as well as to methods for prophylaxis and/or treatment of the above-mentioned diseases and disorders.

Priority: US20040604685P Applic. Date: 2004-08-27; WO2005EP09291 Applic. Date: 2005-08-29

Inventor: KLEBL BERT [DE]; BAUMANN MATTHIAS [DE]; HOPPE EDMUND [DE]; BREHMER DIRK [DE]; DAUB HENRIK [DE]; KERI GYORGY [HU]; VARGA ZOLTAN [HU]; MAROSFALVI JENO [HU]; ORFI LASZLO [HU]


Application No.: US20080187589A1  Published: 07/Aug/2008

Title: MULTI-MODAL DELIVERY VIA TRANSMUCOSAL AND GASTRO-INTESTINAL ABSORPTION OF ANTIHISTAMINES AND SYMPTOM RELIEF

Applicant/Assignee:

Application No.: 12/026303   Filing Date: 05/Feb/2008

Abstract:

A multi-modal absorption, medicine-delivery lozenge is provided. The lozenge includes a lozenge base for oral administration into a user's mouth, a medicinal active ingredient including an antihistamine convertible between ionized and non-ionized states, and a buffer present in an effective amount for establishing a pH in the individual's mouth which is characterized by a simultaneous presence of a first pharmacologically effective dose of the non-ionized form of the medicinal active ingredient for transmucosal absorption, and a second pharmacologically effective dose of the ionized form of the medicinal active ingredient for gastro-intestinal absorption.

Priority: US20070899400P Applic. Date: 2007-02-05

Inventor: PINNEY JOHN M [US]; CONE EDWARD J [US]; CHAU TOMMY L [US]; BUCHHALTER AUGUST R [US]


Application No.: US20080187603A1  Published: 07/Aug/2008

Title: ARTICLE AND METHOD OF NOVEL ANTIMICROBIAL DELIVERY SYSTEM

Applicant/Assignee: QUARTEK CORPORATION

Application No.: 11/868475   Filing Date: 06/Oct/2007

Abstract:

The present invention describes a novel antimicrobial ion delivery system (IDS) article, methods of making the article, and its applications in cleaning dentures and dentistry equipment. The novel IDS entails a source of oligodynamic metal ions embedded in a matrix that allows for the release of metal ions in water at concentrations that are biocidals and prevent biofilm formation. The preferred IDS contains particles made of metallic alloys and bound to a matrix that ensures the controlled release of ions in water. The novel IDS is safe for use in humans and it is environment friendly and biodegradable.

Priority: US20070888343P Applic. Date: 2007-02-06

Inventor: SAWAFTA REYAD I [US]


Application No.: US20080187711A1  Published: 07/Aug/2008

Title: Three-Dimensional Printing Material System With Improved Color, Article Performance, and Ease of Use

Applicant/Assignee: Z CORPORATION

Application No.: 11/972485   Filing Date: 10/Jan/2008

Abstract:

A materials system and methods are provided to enable the formation of articles by three dimensional printing. The materials system includes particulate mixtures having a whitening agent and a solid particulate additive comprising an acid, the latter adapted for modifying a cure rate of an infiltrant. The materials system also includes aqueous fluids including optical brightening agents.

Priority: US20070879703P Applic. Date: 2007-01-10

Inventor: ALAM AMIR [US]; BREDT JAMES F [US]; CLARK NANETTE [US]; FLYNN MARY [US]; SPRAUER JEAN [US]; WILLIAMS DEREK X [US]


Application No.: US20080187881A1  Published: 07/Aug/2008

Title: Matrix Device

Applicant/Assignee:

Application No.: 11/816474   Filing Date: 04/Feb/2006

Abstract:

The invention relates to a matrix device ( 1 ) for tooth treatments comprising a matrix ( 2 ) and at least one wedge ( 3 ), wherein said matrix ( 2 ) is made of a flexible material and is or can be connectable to said solid and reversibly deformable wedge ( 3 ) in such a way that they are embodied in the form of one single component.

Priority: AT20050000261 Applic. Date: 2005-02-17; AT20050001757 Applic. Date: 2005-10-27; WO2006EP00979 Applic. Date: 2006-02-04

Inventor: RUS HARALD [AT]


Application No.: US20080188410A1  Published: 07/Aug/2008

Title: APOPTOSIS-INDUCING POLYPEPTIDES

Applicant/Assignee: ACADEMIA SINICA

Application No.: 11/947935   Filing Date: 30/Nov/2007

Abstract:

An isolated water-soluble VP1 polypeptide of foot-and-mouth disease virus and a nucleic acid encoding the polypeptide. Also disclosed are a pharmaceutical composition containing the polypeptide or nucleic acid and related methods of inducing apoptosis and treating an apoptosis-related disorder.

Priority: US2004-863637 Applic. Date: 2004-06-08; US2003-449531 Applic. Date: 2003-05-29

Inventor: LIANG SHU-MEI [TW]; PENG JEI-MING [TW]; LIANG CHI-MING [TW]


Application No.: US20080188545A1  Published: 07/Aug/2008

Title: Synthesis of pyrrolidine compounds

Applicant/Assignee:

Application No.: 12/005118   Filing Date: 20/Dec/2007

Abstract:

Provided are methods for the preparation of certain substituted pyrrolidine compounds, forms of (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride, and methods for preparing and using these forms.

Priority: US20060876290P Applic. Date: 2006-12-21

Inventor: ALIMARDANOV ASAF R [US]; KRISHNAN LALITHA [US]; ZHOU MAOTANG [US]; WANG TING-ZHONG [US]; REN JIANXIN [US]; CONSIDINE JOHN LEO [US]; WU CHARLES C [US]; BRAZZILLO JASON [US]; RAVEENDRANATH PANOLIL [US]; RAVEENDRANATH GIRIJA [US]; RAVEENDRANATH VIJAY [US]; RAVEEENDRANATH SANJAY [US]; SUTHERLAND KAREN [US]; MIRMEHRABI MAHMOUD [CA]; DESHMUKH SUBODH S [US]


Application No.: US20080188938A1  Published: 07/Aug/2008

Title: Bone Implant Device

Applicant/Assignee: BAYCO TECH LIMITED

Application No.: 11/664838   Filing Date: 06/Oct/2004

Abstract:

The present invention relates to a bone implant device, particularly for dental and orthopedic prosthesis on the vertebral column, having a quicker osteo-integration compared to the prior art devices. Particularly, the present invention relates to an implant device, of metal or polymer nature, a layer of hyaluronic acid being chemically bound on the surface thereof, for use in applications in contact with the bone, with activity of stimulating the bone tissue growth, as well as a process for preparing the same.

Priority: WO2004IB03260 Applic. Date: 2004-10-06

Inventor: GAZZA GIANLUCA [MC]


Application No.: US20080189951A1  Published: 14/Aug/2008

Title: Appliance For Personal Care With Automatic Fluid Dispenser

Applicant/Assignee: KONINKLIJKE PHILIPS ELECTRONICS N.V

Application No.: 11/908774   Filing Date: 15/Mar/2006

Abstract:

An appliance for personal care, such as skin, dental or hair treatment, comprising a dispensing structure ( 30 ) for automatically dispensing a fluid. The dispensing structure ( 30 ) includes a fluid reservoir ( 10 ), a discharge opening ( 11 ) and a fluid drive structure ( 9, 12, 15, 16, 17, 19, 20 ) for driving the fluid to be dispensed from the reservoir ( 10 ) to and out of said discharge opening ( 11 ) in accordance with a dispensing rate/time profile (Sx). The fluid drive structure ( 9, 12, 15, 16, 17, 19, 20 ) is arranged for spurting at least once during said dispensing operation for squirting an additional quantity of the fluid to and out of the discharge opening ( 11 ) in addition to the fluid being dispensed in accordance with said dispensing rate/time profile (Sx).

Priority: EP20050102216 Applic. Date: 2005-03-21; WO2006IB50806 Applic. Date: 2006-03-15

Inventor: MOLEMA JEROEN [NL]; SINNEMA ANKE [NL]; WESTERHOF WILKO [NL]


Application No.: US20080190322A1  Published: 14/Aug/2008

Title: Glove Coating and Manufacturing Process

Applicant/Assignee:

Application No.: 11/672705   Filing Date: 08/Feb/2007

Abstract:

This invention relates to an elastomeric article with improved lubricity and donnablity and reduced stickiness/tackiness. According to the methods of the invention, the internal surface of the elastomeric article is coated with a polyisoprene coating. The coating of the invention is formed from synthetic polyisoprene rubber that may or may not contain minor amounts of other components. The coating is preferably directly bonded to the underlying elastomeric article.

Priority:

Inventor: CHEN SEONG FONG [MY]; WANG SHIPING [US]; WONG WEI CHEONG [MY]; CHONG CHUANG SIM [MY]


Application No.: US20080190455A1  Published: 14/Aug/2008

Title: Method for Drying a Surface

Applicant/Assignee: SEZ AG

Application No.: 11/914315   Filing Date: 11/Apr/2006

Abstract:

Disclosed is a method for drying a surface of a disc-shaped article comprising covering said surface with a rinsing liquid, whereby a closed liquid layer is formed, and removing said rinsing liquid, wherein said rinsing liquid containing at least 50 wt. % water and at least 5 wt. % of a substance, wherein the substance lowers the surface energy of water, wherein said removing of the liquid is initiated by blowing gas onto said closed liquid layer, whereby the closed liquid layer is opened at on discrete area.

Priority: AT20050000831 Applic. Date: 2005-05-13; WO2006EP61522 Applic. Date: 2006-04-11

Inventor: KINOSHITA KEI [AT]; ENGESSER PHILIPP [DE]


Application No.: US20080190787A1  Published: 14/Aug/2008

Title: Hygienic dental floss

Applicant/Assignee:

Application No.: 12/009507   Filing Date: 18/Jan/2008

Abstract:

A dental floss container is provided that may include a container that defines a fluid chamber. A hygienic fluid can be present and may be disposed in the fluid chamber of the container. A spool of dental floss is located in the fluid chamber and engages the hygienic fluid. The spool of dental floss may have a center axis that is oriented in the vertical direction.

Priority: US2006-377766 Applic. Date: 2006-03-15; US20050661875P Applic. Date: 2005-03-15

Inventor: GROSSE TED K [US]


Application No.: US20080190879A1  Published: 14/Aug/2008

Title: Cutting device to disable a childproof container

Applicant/Assignee: APOTHECARY INNOVATIONS, LLC

Application No.: 11/705737   Filing Date: 14/Feb/2007

Abstract:

A method of removing locking tabs from a container or its closure, where the container has threading and locking tabs on an outer surface and its closure has locking tabs on its inner surface, by positioning an apparatus comprising a ring and at least one blade mounted on the ring over the threading on the container or inside the closure and rotating the ring relative to the container or its closure so that the blade removes the locking tabs from the container or its closure.

Priority:

Inventor: HOLTZ WILLIAM E [US]; PARADISI ERIC J [US]


Application No.: US20080190923A1  Published: 14/Aug/2008

Title: Foldable Container for Transporting and/or Storing Goods

Applicant/Assignee: ROVIRA GARRAF S.A

Application No.: 11/914313   Filing Date: 11/May/2006

Abstract:

Foldable container for transporting and/or storing goods, of the type comprising a rigid base structure ( 1 ) and a container element ( 2 ) which contains the goods. Container element ( 2 ) is made up of a foldable bag ( 3 ), made from a foldable laminar material, which at its bottom end is closely joined to rigid base structure ( 1 ), so that the latter defines, either directly or through the laminar material being embedded forming the bag ( 3 ), a rigid base ( 4 ) intended to directly support the goods contained in bag ( 3 ). Thanks to its foldable material condition, when bag ( 3 ) is empty it is suitable for adopting a completely refolded position on said rigid structure ( 1 ) and at least one upright position wherein it has at least one loading mouth ( 5 ) that opens directly for introducing goods.

Priority: ES20050001154 Applic. Date: 2005-05-13; WO2006ES00234 Applic. Date: 2006-05-11

Inventor: ROVIRA FONTANALS CARLOS [ES]; ROVIRA FONTANALS JUAN ERNESTO [ES]


Application No.: US20080193337A1  Published: 14/Aug/2008

Title: Autoclave with Shortenable Work Cycle, Container to be Employed Therewith and Full Sterilisation Treatment Employing Said Container

Applicant/Assignee: W&H STERILIZATION S.R.I

Application No.: 11/817981   Filing Date: 07/Mar/2006

Abstract:

An autoclave for the sterilisation of clinical dental instruments is described, of the type comprising a sterilisation chamber ( 1 ) equipped with a series of appliance fittings ( 4 ) for the inflow and outflow of fluids, and apt to contain a load of instruments onto which to carry through a sterilisation cycle, characterised in that said appliance fittings ( 4 ) are gathered on at least one connection body or partition ( 3 ), with which a reducing container ( 7 ) is quickly able to be engaged and disengaged, which container has a volume apt to contain at least one instrument to be sterilised, the inner volume of such container ( 7 ) communicating with said appliance fittings ( 4 ) and said container ( 7 ) being apt to be entirely contained within said sterilisation chamber ( 1 ). The small-volume container for said autoclave is further described, as well as a full treatment system employing said container.

Priority: IT2005MI00349 Applic. Date: 2005-03-07; WO2006IB50703 Applic. Date: 2006-03-07

Inventor: ONGARO DANELE [IT]; VEDOVELLI RENZO [IT]; RANGE RUEDIGER [IT]


Application No.: US20080193389A1  Published: 14/Aug/2008

Title: Use of glycodendrimer reagents for inhibiting adhesion by microorganisms

Applicant/Assignee:

Application No.: 11/584158   Filing Date: 20/Oct/2006

Abstract:

The present invention is directed to glyodendrimeric proteases, composition with glycodendrimeric proteases and methods for inhibiting adhesion binding in microorganisms by contacting microorganisms with a glycodendrimeric protease or a composition with a glycodendrimeric protease. The invention may be used to treat patients in need of treatment.

Priority: US2003-417768 Applic. Date: 2003-04-16; US2001-824827 Applic. Date: 2001-04-02

Inventor: BOTT RICHARD R [US]; COWAN M M [US]; DAVIS BENJAMIN G [GB]; JONES JOHN BRYAN [CA]


Application No.: US20080193390A1  Published: 14/Aug/2008

Title: Chemical Composition and Process to Obtaining of Remover Product of Carious Tissue and Application of the Product

Applicant/Assignee:

Application No.: 10/569724   Filing Date: 26/Aug/2004

Abstract:

Chemical composition and process to obtaining of remover product of carious tissue and application of the product formed from a base of Methylparaben solubilized in hot distilled water, in which it's added Papain, Chloramine, Sodium Chloride and Colorant, adding the Sodium Hydroxide little by little and, finally, the composition of thickener Carboxymethylcellulose to obtain a kind of Gel applied on caries and, after predetermined waiting period, causing the softening of the contaminated tissue which can be removed by simple curettage, after operating procedures in dentistry.

Priority: US2003-303435 Applic. Date: 2003-08-28; WO2004BR00159 Applic. Date: 2004-08-26

Inventor: BOUCAS MARCIA [BR]; BUSSADORI SANDRA KALIL [BR]


Application No.: US20080193391A1  Published: 14/Aug/2008

Title: Alkyl Sulfate Free and Orthophosphate Free Dentifrice Composition Comprising Fluoride Source and a Silica Dental Abrasive

Applicant/Assignee:

Application No.: 11/909210   Filing Date: 17/Mar/2006

Abstract:

A dentifrice composition is described for combating dental erosion and/or tooth wear comprising a fluoride ion source and a silica dental abrasive, the dentifrice having a Relative Dentine Abrasivity (RDA) value from 20 to 60 and a pH in the range of 6.5 to 7.5 and being free of an orthophosphate buffer or a water soluble salt of a C10-18 alkyl sulfate.

Priority: GB20050005760 Applic. Date: 2005-03-21; GB20050025458 Applic. Date: 2005-12-14; WO2006EP02665 Applic. Date: 2006-03-17

Inventor: NEWBY CRAIG SINCLAIR [GB]; NISBET MARK ANDREW [GB]; PRICE KATHERINE SARAH [GB]


Application No.: US20080193427A1  Published: 14/Aug/2008

Title: Means and Methods for Preventing and/or Treating Caries

Applicant/Assignee: BASF AKTIENGESELLSCHAFT

Application No.: 11/662347   Filing Date: 09/Sep/2005

Abstract:

The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment

and/or (ii) resistant to protease treatment

and/or (iii) calcium-dependent

and/or (iv) formed within a pH range between 4.5 and 8.5

and/or (v) formed in the presence of saliva. Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase

(b) mixing said microorganism with Streptococcus mutans which has been grown to stationary phase

(c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and Streptococcus mutans and (d) detecting aggregates by the occurrence of a pellet. Another aspect of the present invention is an analog or fragment of said microorganism which is thermally inactivated or lyophilized, wherein said analog or fragment retains the capability of specifically binding to Streptococcus mutans. In addition, the present invention encompasses compositions and additives for food, feed or drinks comprising the microorganism belonging to the group of lactic acid bacteria which specifically bind to Streptococcus mutans or an analog or fragment thereof. Moreover, uses of said microorganism or said analog or fragment thereof for the preparation of an anticariogenic or pharmaceutical composition or anticariogenic food or feedstuff as well as methods for producing said compositions or food or feedstuff are provided by the present invention.

Priority: EP20040021591 Applic. Date: 2004-09-10; US20040608381P Applic. Date: 2004-09-10; WO2005EP09724 Applic. Date: 2005-09-09

Inventor: KAESLER BRUNO [DE]; KNOLL ROLF [DE]; BOETTNER MEWES [DE]; BUDDE ECKHARD [DE]; LANG CHRISTINE [DE]; RYSER MARTIN [DE]; VEEN MARKUS [DE]


Application No.: US20080193494A1  Published: 14/Aug/2008

Title: ANTIMICROBIAL SOLID SURFACE MATERIALS CONTAINING CHITOSAN-METAL COMPLEXES

Applicant/Assignee: E. L. DUPONT DE NEMOURS AND COMPANY

Application No.: 12/107253   Filing Date: 22/Apr/2008

Abstract:

Provided are articles containing a solid surface material with an antimicrobial agent in a thermoset and/or thermoplastic resin matrix, wherein the antimicrobial agent comprises a chitosan-metal complex.

Priority: US2004-999672 Applic. Date: 2004-11-30; US2002-324803 Applic. Date: 2002-12-20; US20010343321P Applic. Date: 2001-12-21

Inventor: SABESAN SUBRAMANIAM [US]


Application No.: US20080193557A1  Published: 14/Aug/2008

Title: Dental Mineralization

Applicant/Assignee: THE UNIVERSITY OF MELBOURNE

Application No.: 11/916831   Filing Date: 07/Jun/2006

Abstract:

A method is provided for mineralizing a dental surface or subsurface including contacting the dental surface with a protein disrupting agent and stabilized amorphous calcium phosphate (ACP) or amorphous calcium fluoride phosphate (ACFP).

Priority: AU20050902961 Applic. Date: 2005-06-07; WO2006AU00785 Applic. Date: 2006-06-07

Inventor: REYNOLDS ERIC CHARLES [AU]


Application No.: US20080193566A1  Published: 14/Aug/2008

Title: Use of high dose concentrations of gaseous nitric oxide

Applicant/Assignee:

Application No.: 11/704602   Filing Date: 09/Feb/2007

Abstract:

The invention relates to a methods and devices of delivering gaseous nitric oxide to a mammal or surface at a concentration ranging from about 1000 ppm to about 50,000 ppm of gaseous nitric oxide. Different conditions which can be treated by high dosage administration of gNO include but are not limited to: topical treatments with gNO, cosmetic applications of gNO, vasodilation conditions with gNO, inhalation treatments with gNO, treatments of the blood with gNO, treatment of the skin or tissue with gNO, treatment of infections with gNO, treatment of inflammation on or within the body, and treatments of biofilms with gNO. Other conditions, aliments, or symptoms that may be treated with high dosage gNO include bronchoconstriction, reversible pulmonary vasoconstriction, asthma, pulmonary hypertension, adult respiratory distress syndrome (ARDS), and persistent pulmonary hypertension of the newborn (PPHN).

Priority:

Inventor: MILLER CHRISTOPHER C [CA]; HOLE DOUGLAS R [CA]; LEE ROBERT E [CA]


Application No.: US20080193912A1  Published: 14/Aug/2008

Title: Compositions and Methods for Preparation of Nucleic Acids from Microbial Samples

Applicant/Assignee:

Application No.: 11/659255   Filing Date: 03/Aug/2005

Abstract:

Methods and compositions for releasing the nucleic acids from a variety of different types of microorganisms are provided. The method relies on a simplified lysis procedure that can be applied to many types of bacteria and fungal cells and is readily automated for high throughput screening methods. The method utilizes a high concentration of a chelating agent and a mixture of lysing enzymes to accomplish the disruption of microbial cell walls and allow the release of the nucleic acid.

Priority: US20040598638P Applic. Date: 2004-08-03; WO2005US27715 Applic. Date: 2005-08-03

Inventor: FONG YIU-LIAN [US]; TABRIZI AZITA [US]


Application No.: US20080193915A1  Published: 14/Aug/2008

Title: Isotope Labeled Dinitrophenylhydrazines and Methods of Use

Applicant/Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH

Application No.: 11/575253   Filing Date: 29/Sep/2005

Abstract:

The subject invention provides novel isotope-labeled dinitrophenylhydrazines (DNPHs) and methods for their use in detecting and/or quantifying carbonyl groups in proteins and other analytes. In particular, the present invention provides novel methods for identifying biomarkers of oxidative stress, which can be used to either forecast or detect diseases and/or conditions associated with oxidative stress. In one embodiment of the invention, isotope-labeled DNPHs are derived from [<13>C6]chlorobenzene.

Priority: US20040614951P Applic. Date: 2004-09-29; WO2005US35131 Applic. Date: 2005-09-29

Inventor: PROKAI LASZLO [US]; FORSTER MICHAEL J [US]


Application No.: US20080194477A1  Published: 14/Aug/2008

Title: Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules

Applicant/Assignee:

Application No.: 11/704141   Filing Date: 07/Feb/2007

Abstract:

Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines.

Priority: US2003-658834 Applic. Date: 2003-09-08; US20030457135P Applic. Date: 2003-03-21; US20020409898P Applic. Date: 2002-09-09

Inventor: GANTIER RENE [FR]; VEGA MANUEL [FR]; DRITTANTI LILA [FR]; GUYON THIERRY [FR]


Application No.: US20080194504A1  Published: 14/Aug/2008

Title: Rna-Mediated Interference to Control Disease in Terrestrial and Aquaculture Animals

Applicant/Assignee: ADVANCED BIONUTRITION CORPORATION

Application No.: 10/588414   Filing Date: 04/Feb/2005

Abstract:

The invention is directed to compositions (e.g., feeds, feed supplements, and therapeutic products) and methods for inhibiting an animal pathogen using RNA-interference technology.

Priority: US20040542391P Applic. Date: 2004-02-06; WO2005US03715 Applic. Date: 2005-02-04

Inventor: KYLE DAVID J [US]; DHAR ARUN K [US]


Application No.: US20080194574A1  Published: 14/Aug/2008

Title: Pyrazine Derivatives As Effective Compounds Against Infectious Diseases

Applicant/Assignee: AXXIMA PHARMACEUTICALS AG

Application No.: 10/596508   Filing Date: 12/Dec/2006

Abstract:

The present invention relates to pyrazine derivatives according to the general formula (I) and pharmaceutically acceptable salts thereof and their use as pharmaceutical compounds as well as the use of these compounds for the preparation of a pharmaceutical composition for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases, stroke and especially for the treatment of herpesviral induced infections, including opportunistic infections as well as infections and diseases caused by human cytomegalovirus (HCMV).

Priority: EP20030029038 Applic. Date: 2003-12-16; US20030530612P Applic. Date: 2003-12-19; WO2004EP14371 Applic. Date: 2004-12-16

Inventor: EIKHOFF JAN EIKE [DE]; ASHTON MARK RICHARD [GB]; COURTNEY STEPHEN MARTIN [GB]; YARNOLD CHRISTOPHER JOHN [GB]; VARRONE MAURIZIO [GB]; LOKE PUI LENG [GB]; HERGET THOMAS [DE]; SCHWAB WILFRIED [DE]; HAFENBRADL DORIS [DE]


Application No.: US20080194618A1  Published: 14/Aug/2008

Title: Muscarinic Acetylcholine Receptor Antagonists

Applicant/Assignee: GLAXO GROUP LIMITED

Application No.: 12/063719   Filing Date: 17/Aug/2006

Abstract:

Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.

Priority: US20050709301P Applic. Date: 2005-08-18; WO2006US32138 Applic. Date: 2006-08-17

Inventor: LAINE DRAMANE I [US]; PALOVICH MICHAEL R [US]; MCCLELAND BRENT W [US]


Application No.: US20080194681A1  Published: 14/Aug/2008

Title: Novel Inhibitors of Histone Deacetylase for the Treatment of Disease

Applicant/Assignee: KALYPSYS, INC

Application No.: 11/792624   Filing Date: 09/Dec/2005

Abstract:

Disclosed herein are carbonyl compounds of Formula: (I) as described herein. Compounds as modulators of his-tone deacetylase (HDAC), pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.

Priority: US20040634844P Applic. Date: 2004-12-09; US20050692856P Applic. Date: 2005-06-22; WO2005US44743 Applic. Date: 2005-12-09

Inventor: MALECHA JAMES [US]; NOBLE STEWART [US]; HASSIG CHRISTIAN [US]; WASH PAUL [US]; WILEY BRANDON [US]; LAWRENCE CHARLES [US]; HOFFMAN TIMOTHY [US]; BONNEFOUS CELINE [US]; SMITH NICHOLAS [US]


Application No.: US20080194722A1  Published: 14/Aug/2008

Title: Dental Compositions Containing Hybrid Monomers

Applicant/Assignee:

Application No.: 11/912949   Filing Date: 09/May/2006

Abstract:

The invention features dental compositions comprising at least one hybrid monomer that comprises a cyclic allylic sulfide moiety attached to a (meth)acryloyl moiety. These two functional moieties are typically joined either directly to each via a chemical bond or through some chemical structure or spacer molecule. The composition may optionally contain additional polymerizable compounds, such as ethylenically unsaturated compounds, that are typically used in dental compositions.

Priority: US20050678986P Applic. Date: 2005-05-09; WO2006US17833 Applic. Date: 2006-05-09

Inventor: ABUELYAMAN AHMED S [US]; MITRA SUMITA B [US]; LEWANDOWSKI KEVIN M [US]; PLAUT DAVID J [US]


Application No.: US20080194730A1  Published: 14/Aug/2008

Title: Hydrolysis stable self-etching, self-priming adhesive

Applicant/Assignee:

Application No.: 12/077644   Filing Date: 20/Mar/2008

Abstract:

An aqueous one-pack self-etching and self-priming dental adhesive composition having a pH of at most 2, which comprises: (i) a polymerizable N-substituted alkylacrylic or acrylic acid amide monomer which optionally contains an inorganic acidic moiety selected from a phosphonic acid moiety or a sulfonic acid moiety, and (ii) a curing system.

Priority: US20010345994P Applic. Date: 2001-10-26; WO2002EP11940 Applic. Date: 2002-10-25; US2004-493721 Applic. Date: 2004-04-26

Inventor: KLEE JOACHIM [DE]; WALZ UWE [DE]; LEHMANN UWE [DE]


Application No.: US20080194753A1  Published: 14/Aug/2008

Title: Aqueous Dispersions of Water-Soluble and/or Water/Swellable Anionic Polymers, Method for the Production Thereof and Use Thereof

Applicant/Assignee: BASF AKTIENGESELLSCHAFT

Application No.: 11/914242   Filing Date: 17/May/2006

Abstract:

An aqueous dispersion of water-soluble and/or water-swellable anionic polymers which are obtainable by free radical polymerization of ethylenically unsaturated, anionic monomers in an aqueous medium in the presence of at least one stabilizer, the polymerization being carried out in the presence of at least one water-soluble polymer of the groups consisting of (a) graft polymers of vinyl acetate and/or vinyl propionate on (i) polyethylene glycols or (ii) polyethylene glycols or polypropylene glycols endcapped at one or both ends with alkyl, carboxyl or amino groups, polyalkylene glycols, polyalkylene glycols endcapped at one or both ends with alkyl, carboxyl or amino groups and (b) water-soluble copolymers from the group consisting of homo- and copolymers of anionic monomers, copolymers of anionic and cationic and, if appropriate, neutral monomers, the proportion of the anionic monomers incorporated in the form of polymerized units being greater than that of cationic monomers and copolymers of at least one anionic monomer and at least one monomer from the group consisting of the esters of anionic monomers with monohydric alcohols, styrene, N-vinylpyrrolidone, N-vinylcaprolactam, N-vinylimidazole, N-vinylformamide, acrylamide, methacrylamide, vinyl acetate and vinyl propionate as a stabilizer, processes for the preparation of the aqueous dispersions by free radical polymerization of ethylenically unsaturated, anionic monomers in an aqueous medium in the presence of a stabilizer of the abovementioned groups (a) and (b) and use of the aqueous dispersions as thickeners for paper coating slips, pigment print pastes, print pastes for transfer printing, dispersion printing, printing with acid and metal complex dyes, reactive printing and vat printing, for tertiary mineral oil production, for consolidating nonwovens, for water-based paints, pharmaceutical products, dental compounds, agrochemicals and extinguishing agents and as coating materials and as an additive in detergents and cleaning agents.

Priority: DE200510023799 Applic. Date: 2005-05-19; WO2006EP62380 Applic. Date: 2006-05-17

Inventor: MUKHERJEE PULAKESH [DE]; NOWACK ROLAND [DE]; BOLTER HENNING [DE]


Application No.: US20080196643A1  Published: 21/Aug/2008

Title: Hemming system and method for hemming a fabric without using seams, by introducing an adhesively processed resilient element into one or two opposite surfaces of the fabric

Applicant/Assignee: MACPI-PRESSING DIVISION S.P.A

Application No.: 11/810094   Filing Date: 04/Jun/2007

Abstract:

A hemming system for hemming a fabric, without using seams, and by introducing an adhesively processed element into a surface or between two opposite surfaces of the fabric, comprises an adhesive applying module for applying two adhesive materials to an elastic or resilient element and to the fabric, and a second hemming module, for hemming the fabric at the resilient element.

Priority: IT2007MI00300 Applic. Date: 2007-02-16

Inventor: CARTABBIA GIOVANNI [IT]


Application No.: US20080196998A1  Published: 21/Aug/2008

Title: Rail Element For Conveying Suspended Objects, Preform-Supply Device Comprising One Such Element And Curved Flat Band Which Can Be Fixed To One Such Element

Applicant/Assignee: SIDEL PARTICIPATIONS

Application No.: 11/915523   Filing Date: 23/May/2006

Abstract:

The invention relates to a rail element for conveying suspended objects, such as bottles or preforms. The inventive element comprises two guide rails ( 11, 12 ) which are separated by a pre-defined distance and which form lateral support surfaces for the objects being conveyed along a conveyor passageway ( 13 ), such as preform sub-neck guides. The invention is characterised in that it defines a helically-curved conveyor section and consists of a frame ( 10 ) on which the guide rails ( 11, 12 ) are helically arranged, whereby at least one guide rail ( 11, 12 ) comprises a flat band that can be removed from the frame ( 10 ).

Priority: FR20050005200 Applic. Date: 2005-05-24; WO2006FR01182 Applic. Date: 2006-05-23

Inventor: LEMAISTRE ERIC [FR]; CHARPENTIER ALAIN [FR]; SAVARY CYRIL [FR]


Application No.: US20080197099A1  Published: 21/Aug/2008

Title: Non-removable closure

Applicant/Assignee:

Application No.: 11/708505   Filing Date: 20/Feb/2007

Abstract:

The present invention is a non-removable closure. A non-removable closure in accordance with the present invention may comprise (a) a first sealant layer

(b) a sealant interface layer

and (c) a second sealant layer. A non-refillable container for flowable materials in accordance with the present invention may comprise: (a) a cap

(b) a first sealant layer

(c) a sealant interface layer

(d) a second sealant layer

and (e) a flowable material receptacle. A method for manufacturing a non-removable bottle closure in accordance with the present invention may comprise the steps: (a) disposing a first sealant layer on a first surface of a sealant interface layer

(b) disposing a second sealant layer on a second surface of the sealant interface layer

(c) adhering the first sealant layer to a cap

and (d) adhering the second sealant layer to a receptacle mouth.

Priority:

Inventor: PAWLICK ADAM [US]; CZAJKOWSKI DOUG [US]


Application No.: US20080199356A1  Published: 21/Aug/2008

Title: System with adapter for cleaning medical appliances

Applicant/Assignee: ORO CLEAN CHEMIE AG

Application No.: 12/068092   Filing Date: 01/Feb/2008

Abstract:

An adapter ( 1 ) for cleaning a medical appliance comprises a fluid channel ( 2 ) with an inlet ( 3 ) and at least one outlet ( 4.1 ), at least one outlet being provided with a coupling means ( 5.1 ) for an opening of a medical device. The coupling means ( 5.1 ) is designed as a single-use coupling which, after the medical device has been coupled for the first time, generates a leak in the fluid channel at the time of uncoupling. This ensures totally hygienic cleaning of medical devices.

Priority: EP20070405031 Applic. Date: 2007-02-05

Inventor: SUTER URSULA [CH]


Application No.: US20080199412A1  Published: 21/Aug/2008

Title: ANTI-STAINING ANTIBACTERIAL DENTIFRICE

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/100922   Filing Date: 10/Apr/2008

Abstract:

An anti-staining, antibacterial dentifrice comprises an anti-staining effective amount of an orally acceptable polymer or copolymer that comprises a plurality of monomeric groups of formula (I) wherein (a) one of A and A' is hydrogen and the other is a moiety (X)n(R)m, (b) n in individual such moieties is independently 0 or 1, (c) linking groups X if present independently comprise an oxygen, sulfur, nitrogen, phosphorus or silicon atom, (d) where n is 0, m is 1, and where n is 1, m is independently an integer from 1 to 3 as determined by X, (e) terminal groups R are independently hydrogen or C1-18 organic radicals, and (t) M and M' are independently selected from hydrogen, alkali metal and ammonium

said polymer or copolymer having an average molecular weight of at least about 1,000. The dentifrice further comprises an antibacterial effective amount of an orally acceptable halogenated diphenylether antibacterial agent, and an antibacterial enhancing effective amount of an orally acceptable polyvinylmethylether/maleic anhydride copolymer.

Priority: US2004-859264 Applic. Date: 2004-06-02

Inventor: MILANOVICH NEBOJSA [US]; GAFFAR ABDUL [US]; PRENCIPE MICHAEL [US]; BOYD THOMAS [US]


Application No.: US20080199417A1  Published: 21/Aug/2008

Title: Personal Care Composition Comprising Saccharide-Siloxane Copolymers

Applicant/Assignee: DOW CORNING CORPORATION GENENCOR INTERNATIONAL, INC

Application No.: 11/915051   Filing Date: 23/May/2006

Abstract:

A personal care composition comprising at least one saccharide-siloxane copolymer having a saccharide component and an organosiloxane component and linked by a linking group, wherein the saccharide-siloxane copolymer has a specified formula, is provided. The personal care composition is adapted to provide at least one benefit to the at least one portion of the body to which it is applied. Emulsions, methods for preparing emulsions comprising saccharide-siloxane copolymers, and personal care products comprising the personal care compositions and emulsions are also provided.

Priority: US20050683590P Applic. Date: 2005-05-23; WO2006US20210 Applic. Date: 2006-05-23

Inventor: JOFFRE ERIC JUDE [US]; JOHNSON BETHANY K [US]; SWANTON BRIAN JEFFERY [US]; STARCH MICHAEL STEPHEN [US]


Application No.: US20080199461A1  Published: 21/Aug/2008

Title: Ovr 110 Antibody Compositions and Methods of Use

Applicant/Assignee: DIADEXUS, INC

Application No.: 11/813528   Filing Date: 09/Jan/2006

Abstract:

The invention provides isolated anti-head and neck, ovarian, pancreatic, lung, endometrial or breast cancer antigen (Ovr110) antibodies that internalize upon binding to Ovr110 on a mammalian in vivo. The invention also encompasses compositions comprising an anti-Ovr110 antibody and a carrier. These compositions can be provided in an article of manufacture or a kit. Another aspect of the invention is an isolated nucleic acid encoding an anti-Ovr110 antibody, as well as an expression vector comprising the isolated nucleic acid. Also provided are cells that produce the anti-Ovr110 antibodies. The invention encompasses a method of producing the anti-Ovr110 antibodies. Other aspects of the invention are a method of killing an Ovr110-expressing cancer cell by contacting the cancer cell with an anti-Ovr110 antibody and a method of alleviating or treating an Ovr110-expressing cancer in a mammal by administering a therapeutically effective amount of the anti-Ovr110 antibody to the mammal.

Priority: US20050642490P Applic. Date: 2005-01-07; WO2006US00575 Applic. Date: 2006-01-09

Inventor: PAPKOFF JACKIE [US]; SHROYER KENNETH R [US]


Application No.: US20080199475A1  Published: 21/Aug/2008

Title: NOVEL GLYCOSYLATED PEPTIDE TARGET IN NEOPLASTIC CELLS

Applicant/Assignee: PATRYS LIMITED

Application No.: 11/945916   Filing Date: 27/Nov/2007

Abstract:

The invention provides polypeptide, nucleic acid and other compositions. Polypeptide, nucleic acid and other compositions are useful in treatment and diagnostic methods. One treatment method includes inhibiting growth or proliferation of hyperproliferative cells or inducing regression of hyperproliferative cells, such as cells of a cellular hyperproliferative disorder, or reducing levels of LDL or oxLDL.

Priority: US20060867285P Applic. Date: 2006-11-27

Inventor: VOLLMERS HEINZ PETER [DE]


Application No.: US20080199491A1  Published: 21/Aug/2008

Title: Sustained Release Vaccine Composition

Applicant/Assignee:

Application No.: 11/629681   Filing Date: 16/Jun/2005

Abstract:

A non-liquid vaccine composition including one or more antigen component(s)

a pharmaceutically acceptable non-liquid adjuvant therefor

and optionally a non-liquid vaccine protection agent.

Priority: AU20040903283 Applic. Date: 2004-06-16; AU20050900928 Applic. Date: 2005-02-28; WO2005AU00869 Applic. Date: 2005-06-16

Inventor: BRANDON MALCOLM [AU]; MARTINOD SERGE [US]


Application No.: US20080199509A1  Published: 21/Aug/2008

Title: Methods and Compositions for the Disruption of Biofilms

Applicant/Assignee: NATIONAL JEWISH MEDICAL AND RESEARCH CENTER

Application No.: 12/031029   Filing Date: 14/Feb/2008

Abstract:

The invention relates to methods of inhibiting biofilm formation or reducing biofilms in a subject or on a device or surface by administering a charged compound such as a polyamino acid to a subject, device or surface. The invention also relates to compositions for inhibiting biofilm formation or reducing biofilms.

Priority: US20070890168P Applic. Date: 2007-02-15

Inventor: NICK JERRY A [US]; PARKS QUINN M [US]


Application No.: US20080199570A1  Published: 21/Aug/2008

Title: Package for Foodstuff Products

Applicant/Assignee: SOREMARTEC S.A

Application No.: 11/917623   Filing Date: 08/Jun/2006

Abstract:

A package ( 1 ) for touch-sensitive foodstuff products (P), such as chocolates or pralines, comprises:-a tray-like container ( 2 ) made of elastically deformable material that is able to receive a first part of the product (P) and has a mouth edge ( 3 ) that surrounds the product (P), allowing a substantial part thereof to emerge therefrom

and-a film ( 4 ) made of a material that is tearable and deformable in a plastic way, shaped according to a general dome-like conformation so as to contain, in the absence of stresses, the aforesaid substantial part of the product (P) emerging from the mouth edge ( 3 ) of the tray-like container ( 3 )

the tray-like container ( 2 ) and the film ( 4 ) are connected to one another in conditions of hermetic seal at the mouth edge ( 3 ) of the tray-like container ( 2 ).

Priority: IT2005TO00471 Applic. Date: 2005-07-08; WO2006IB01692 Applic. Date: 2006-06-08

Inventor: MILANO GIUSEPPE [IT]


Application No.: US20080199826A1  Published: 21/Aug/2008

Title: Dental Composite

Applicant/Assignee:

Application No.: 11/676807   Filing Date: 20/Feb/2007

Abstract:

The shade system contains a set of dentin/body shades, and a set of enamel and opaque shades that correspond to the dentin/body shades. The system may also include tints and specialty incisals to provide special effects, if necessary.

Priority:

Inventor: JIA WEITAO [US]; JIN SHUHUA [US]


Application No.: US20080199830A1  Published: 21/Aug/2008

Title: Iontophoresis and Active Dental Appliances

Applicant/Assignee:

Application No.: 12/033827   Filing Date: 19/Feb/2008

Abstract:

Dental trays, toothbrushes, and other devices are provided for the active delivery of medicaments into hard and soft tissues, particularly those of the oral cavity. The devices apply an AC voltage with a DC offset to drive medicaments into the tissues.

Priority: US20070902001P Applic. Date: 2007-02-16

Inventor: FONTENOT MARK G [US]; HOULE PHILIP R [US]


Application No.: US20080199831A1  Published: 21/Aug/2008

Title: Process and Device For Cleaning Teeth With Sonic Energy

Applicant/Assignee:

Application No.: 11/913955   Filing Date: 21/Apr/2006

Abstract:

A process and device are disclosed for cleaning teeth with sonic energy, in particular audible sound or ultrasound. Sound is conducted to the teeth ( 5 ) through a liquid ( 6 ) in an oral cavity ( 3 ). Sound is applied from the outer side ( 2 ) of the oral cavity (3).

Priority: DE200510021261 Applic. Date: 2005-05-09; WO2006EP03711 Applic. Date: 2006-04-21

Inventor: TEICHERT KLAUS [DE]; GRANDY ELMAR [DE]


Application No.: US20080199911A1  Published: 21/Aug/2008

Title: VP1 OF FOOT-AND-MOUTH DISEASE VIRUS

Applicant/Assignee: ACADEMIA SINICA

Application No.: 11/748294   Filing Date: 14/May/2007

Abstract:

A pure, water-soluble polypeptide containing one or more monomers of a VP1 protein of a foot-and-mouth disease virus

or a pure, water-insoluble polypeptide comprising two or more monomers of a VP1 protein of a foot-and-mouth disease virus. Also disclosed are a vaccine containing the polypeptide, a method of producing the polypeptide, and a method of inducing an immune response in a subject by administering to the subject an effective amount of the polypeptide.

Priority: US2003-449531 Applic. Date: 2003-05-29

Inventor: LIANG SHU-MEI [TW]; WANG JENG-HWAN [TW]; SHIEH JENG-JER [TW]


Application No.: US20080200585A1  Published: 21/Aug/2008

Title: Sulfonium Initiators, Process For Production And Use In Cationic Polymerizable Compositions

Applicant/Assignee:

Application No.: 11/997192   Filing Date: 27/Jul/2006

Abstract:

The invention relates to an initiator comprising at least one structural element characterized by the following formula (I) wherein X<-> is a non or low coordinating anion, R1, R2, R3, R4 are independently linear, cyclic or branched C1-C20 alkyl or alkylene groups, wherein one or more of the methylene groups contained in the alkyl or alkylene group can be substituted by -CO-, -CONH-, -CON(CH3)-, -S- and/or -O-, and wherein R1, R2, R3 and/or R4 can act as a bridging element connecting two or more structural elements. The invention is also related to a process of producing the initiator and to a curable composition comprising the initiator, a process for producing the curable composition a kit comprising a cationically curable composition and the inventive initiator and the use of the initiator or the curable composition comprising the initiator for various applications, especially in the dental field.

Priority: EP20050016531 Applic. Date: 2005-07-29; WO2006US29311 Applic. Date: 2006-07-27

Inventor: KLETTKE THOMAS [DE]; FUEHRER CORNELIA B [DE]; HAILAND ANDREA [DE]; MIKULLA MARKUS [DE]


Application No.: US20080200586A1  Published: 21/Aug/2008

Title: Dental/Surgical Sealants Including Shapeable Particles

Applicant/Assignee:

Application No.: 11/632104   Filing Date: 18/Jul/2005

Abstract:

A sealant composition, suitable for surgical or dental use, comprises a sealant and, dispersed therein, one or more particles of a material which is prestressed and/or capable of undergoing expansion or contraction.

Priority: GB20040015981 Applic. Date: 2004-07-16; WO2005GB02811 Applic. Date: 2005-07-18

Inventor: HOLDEN PAUL STEPHEN [GB]; HEATH ALEXANDRA ELIZABETH [GB]


Application No.: US20080200630A1  Published: 21/Aug/2008

Title: Medical Resin Composition, Process For Producing Resin Composition and Process For Producing Molded Article

Applicant/Assignee: NATIONAL UNIVERSITY CORPORATION OKAYUAMA

Application No.: 11/795502   Filing Date: 19/Jan/2006

Abstract:

A medical resin composition is produced by mixing a powder of a polymer (A) comprising repeating units having an ester group and a liquid of a vinyl ester monomer (B) having 6 or more carbon atoms to increase a viscosity and, according to demand, further performing a polymerization reaction. The thus produced resin composition inhibits leaching of irritative substances, reduces any adverse effects on the human body by endocrine disruptors, etc. and can be prepared with high operational efficiency. The resin composition is suitably used as a dental resin composition such as a tissue conditioner, a functional impression material, a lining material, a denture base material or a mouth piece material.

Priority: JP20050013231 Applic. Date: 2005-01-20; WO2006JP00772 Applic. Date: 2006-01-19

Inventor: TANAKA JIRO [JP]; SUZUKI KAZUOMI [JP]


Application No.: US20080202516A1  Published: 28/Aug/2008

Title: Portable pulmonary body core cooling and heating system

Applicant/Assignee:

Application No.: 12/070435   Filing Date: 19/Feb/2008

Abstract:

This invention relates to a fully adjustable Portable Pulmonary Body Core Cooling and Heating System specifically designed to provide several hours of high efficiency cooling or heating when worn and operated by a user. This combination Portable Pulmonary Body Core Cooling and Heating System invention is capable of delivering several hours of high efficiency personal cooling or heating without the use of caustic or toxic chemicals with virtually no risk of injury associated with its use. This Portable Pulmonary Body Core Cooling and Heating System invention utilizes the user's own pulmonary system to regulate core body temperature by introducing controlled temperature air into the user's lungs by their own breathing process.

Priority: US20070903202P Applic. Date: 2007-02-23

Inventor: HARVIE MARK R [US]


Application No.: US20080206159A1  Published: 28/Aug/2008

Title: COMPOSITIONS WITH MODULATING AGENTS

Applicant/Assignee: FOAMIX LTD

Application No.: 11/947751   Filing Date: 29/Nov/2007

Abstract:

The present invention relates to a waterless composition and foam as a vehicle in which an active pharmaceutical or cosmetic agent, when added is stable or stabilized by or its destabilization is impeded by the presence of a modulating agent. The pharmaceutical or cosmetic composition and foam, includes: a waterless solvent, a modulating agent and one or more active pharmaceutical or cosmetic agents. The present invention also relates to a method of treatment administering the waterless composition and foam.

Priority: US2004-835505 Applic. Date: 2004-04-28; US2006-430599 Applic. Date: 2006-05-09; US20030492385P Applic. Date: 2003-08-04; US20030530015P Applic. Date: 2003-12-16; US20050679020P Applic. Date: 2005-05-09; US20060784793P Applic. Date: 2006-03-21; US20060861620P Applic. Date: 2006-11-29

Inventor: TAMARKIN DOV [IL]; EINI MEIR [IL]; FRIEDMAN DORON [IL]; BERMAN TAL [IL]; SCHUZ DAVID [IL]


Application No.: US20080206322A1  Published: 28/Aug/2008

Title: Pharmaceutical Multiparticulate Composit Ion Comprising Mycophenolic Acid or Myco Phenolate Sodium and Combination Compositions with Rapamycin

Applicant/Assignee: NOVARTIS AG

Application No.: 11/573647   Filing Date: 29/Aug/2005

Abstract:

The present invention relates to a novel composition, e.g. of mycophenolic acid, a salt or a prodrug thereof, in a modified release form.

Priority: GB20040019355 Applic. Date: 2004-08-31; WO2005EP09295 Applic. Date: 2005-08-29

Inventor: BECKER DIETER [DE]; BEYER JUTTA [CH]; KERC JANEZ [SI]; KRAMER ANDREA [DE]; LOGGIA NICOLETTA [CH]; LUFTENSTEINER CHIRSTIAN-PETER [CH]; OGORKA JORG [DE]


Application No.: US20080206554A1  Published: 28/Aug/2008

Title: Hydroxyapatite With Controllable Size And Morphology

Applicant/Assignee: RUTGERS, THE STATE UNIVERSITY

Application No.: 11/813368   Filing Date: 21/Dec/2005

Abstract:

A ceramic powder of non-agglomerated non-aggregated phase-pure hydroxyapatite having a controllable morphology. Also presented is a film of phasepure crystalline hydroxyapatite grains having a controllable morphology. Methods for preparing the same are also provided.

Priority: US20050641083P Applic. Date: 2005-01-04; WO2005US46209 Applic. Date: 2005-12-21

Inventor: RIMAN RICHARD E [US]; BURUKHIN ALEXANDER [RU]; ZLOTNIKOV EUGENE [US]; HADERS DAN [US]


Application No.: US20080206706A1  Published: 28/Aug/2008

Title: Hand Apparatus, In Particular For Dental Purposes, For Dispensing a Pasty Filler Mass

Applicant/Assignee: KALTENBACH & VOIGT GMBH

Application No.: 11/993968   Filing Date: 21/Jun/2006

Abstract:

A hand apparatus, in particular for dental purposes, for dispensing a pasty filler mass the viscosity of which can be reduced by supplying vibration energy, comprising an apparatus housing, a container for the pasty filler mass, an exit nozzle connected with the container, a vibration generator, and pressure production means for applying pressure on the pasty filler mass. In order to improve the transfer of vibrations in the region of the hand apparatus the vibration generator and the container are mounted movably with respect to the apparatus housing and are directly vibration-coupled with each other.

Priority: DE200510028925 Applic. Date: 2005-06-22; WO2006EP05973 Applic. Date: 2006-06-21

Inventor: MOSSLE WALTER [DE]


Application No.: US20080206712A1  Published: 28/Aug/2008

Title: RESIN REINFORCED ZINC POLYCARBOXYLATE TEMPORARY CEMENT COMPOSITIONS AND RELATED KITS AND METHODS

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/680284   Filing Date: 28/Feb/2007

Abstract:

Two-part resin-reinforced cement compositions, kits, and related methods are used for bonding a dental prosthetic appliance to a tooth. A first part includes an amine activator component and a zinc oxide reactive filler, while a second part includes a polymerization initiator (e.g., benzoyl peroxide) and a polymerizable component having a structure including at least one acrylate or methacrylate group at one end and a carboxylic acid group at another end. A temporary cement composition advantageously exhibits reduced compressive and/or bonding strength relative to permanent cement compositions, which provides sufficient strength to facilitate normal use of the teeth while the provisional appliance is in use, while also facilitating easy removal of the provisional appliance for replacement with a permanent appliance at a later time.

Priority:

Inventor: KENNARD GORDON [US]; KAWAMOTO ANDY T [US]; WAGNER JEFF [US]


Application No.: US20080206713A1  Published: 28/Aug/2008

Title: Thermochromic Material for Dental Impression and Method

Applicant/Assignee: ZHERMACK S.P.A

Application No.: 11/917483   Filing Date: 07/Jun/2006

Abstract:

The present invention relates to a thermochromic material for dental impression, capable of reversibly changing colour depending on the temperature at which said material is found, a method for its preparation and the use thereof. Said material includes a bicomponent silicone composition in combination with at least a thermochromic pigment.

Priority: EP20050425428 Applic. Date: 2005-06-15; WO2006IB01485 Applic. Date: 2006-06-07

Inventor: BUSIN TIZIANO [IT]; ROSSI MASSIMO [IT]; CALLEGARO FRANCESCO [IT]


Application No.: US20080206715A1  Published: 28/Aug/2008

Title: COLOR CHANGING DENTAL ADHESIVE COMPOSITIONS AND RELATED METHODS AND KITS

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/680379   Filing Date: 28/Feb/2007

Abstract:

Methods, compositions, and kits for use in facilitating detection and removal of dental adhesives while minimizing and/or eliminating removal of adjacent tooth tissue. A pH sensitive color changing component (i.e., an acid/base indicator) is included within a dental adhesive composition or an activating wash composition. The adhesive composition is used to bond a dental appliance (e.g., a provisional restorative appliance or an orthodontic bracket) to a tooth. When it becomes necessary to remove the dental appliance, selective removal of the dental adhesive while minimizing and/or eliminating removal of enamel or other adjacent tooth tissue are facilitated because of the inclusion of a pH sensitive color-changing component within the dental adhesive or activating wash composition. The adhesive changes from a first color having low contrast relative to adjacent tooth tissue to a second color having greater contrast relative to adjacent tooth tissue upon application of the activating wash.

Priority:

Inventor: KAWAMOTO ANDY T [US]; KENNARD GORDON [US]; WAGNER JEFF [US]


Application No.: US20080206843A1  Published: 28/Aug/2008

Title: Compositions and methods for prion decontamination

Applicant/Assignee:

Application No.: 11/977844   Filing Date: 26/Oct/2007

Abstract:

The invention relates to compositions and methods for prion degradation, decontamination or disinfection. The composition comprises an oxidizing agent, one or more proteases and a surfactant such as an ionic surfactant/detergent. The method comprises contacting a prion contaminated entity with a prion-degrading composition comprising an effective amount of an oxidizing agent, an effective amount of at least one protease, and an effective amount of a surfactant. The components of the composition may be contacted with a prion-contaminated entity sequentially or simultaneously using an aqueous composition. Typically at least two different proteases are used for optimal efficacy. Preferably the oxidizing agent comprises peracetyl ions or a source thereof. The invention also relates to kits comprising the various reagents.

Priority: US20070925177P Applic. Date: 2007-04-19; US20060854831P Applic. Date: 2006-10-27

Inventor: CROUD VINCENT BRIAN [GB]; COLLINGE JOHN [GB]; JACKSON GRAHAM [GB]


Application No.: US20080206854A1  Published: 28/Aug/2008

Title: Reactors (medical devices) in which chemical, biochemical, biological reactions - activations take place and their final products are used

Applicant/Assignee:

Application No.: 12/072249   Filing Date: 25/Feb/2008

Abstract:

Reactors (medical devices), which contains one or more independent of each other solutions and has two or more openings with corresponding indented hollow caps and/or pump and/or needle on the other opening as delivery system. The caps contain within them sensitive or incompatible enzymes, chemical, biological, or synthetic substances in powder or tablet form. Indicative of these caps is the fact that when impressed or twisted the protective seal within is broken, releasing their content into the solution or solutions contained within the vial in the order where the desired reactions will take place and the final products will be used by the user for pharmaceutical, cosmetic, nutritional, diagnostic, and other purposes.

Priority: GR20070100115 Applic. Date: 2007-02-23

Inventor: TSAKAS EDUARDOS SPIRIDON [GR]; TSAKAS SPIRIDON [GR]


Application No.: US20080207556A1  Published: 28/Aug/2008

Title: Product and Process for Inhibition of Biofilm Development

Applicant/Assignee: NATIONAL JEWISH MEDICAL AND RESEARCH CENTER

Application No.: 12/115880   Filing Date: 06/May/2008

Abstract:

Disclosed are compositions and methods for the inhibition of biofilm formation or reduction of existing or developing biofilms in a patient. These methods also inhibit the aggregation of bacteria that form biofilms in the airways. The methods include administering to a subject that has or is at risk of developing biofilms a compound or formulation that inhibits the formation or polymerization of actin microfilaments or depolymerizes actin microfilaments at or proximal to the site of biofilm formation. Such a compound can be administered in combination with a compound or formulation that inhibits the accumulation or activity of cells that are likely to undergo necrosis at or proximal to the site of biofilm formation (i.e., neutrophils). The methods and compositions can further include the use of anti-DNA and/or anti-mucin compounds, as well as other therapeutic compounds and compositions.

Priority: US2005-197897 Applic. Date: 2005-08-04; US20040599495P Applic. Date: 2004-08-06

Inventor: NICK JERRY A [US]; WALKER TRAVIS S [US]; WORTHEN G SCOTT [US]


Application No.: US20080207619A1  Published: 28/Aug/2008

Title: Diaminopyrimidines as P2X3 and P2X2/3 modulators

Applicant/Assignee: ROCHE PALO ALTO LLC

Application No.: 12/072663   Filing Date: 27/Feb/2008

Abstract:

Compounds and methods for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the compounds being of formula (I): wherein R<1>, R<2>, R<3 >and R<4 >are as defined herein.

Priority: US20070904077P Applic. Date: 2007-02-28

Inventor: DILLON MICHAEL PATRICK [US]; JAHANGIR ALAM [US]


Application No.: US20080207655A1  Published: 28/Aug/2008

Title: Diaminopyrimidines as P2X3 and P2X2/3 modulators

Applicant/Assignee: ROCHE PALO ALTO LLC

Application No.: 12/072664   Filing Date: 27/Feb/2008

Abstract:

Compounds of formula (I): wherein R<1 >and R<2 >are as defined herein. Also disclosed are methods of making and using the subject compounds.

Priority: US20070904079P Applic. Date: 2007-02-28

Inventor: DILLON MICHAEL PATRICK [US]; DU BOIS DAISY JOE [US]; JAHANGIR ALAM [US]


Application No.: US20080207662A1  Published: 28/Aug/2008

Title: Once daily dosage forms of trospium

Applicant/Assignee: SUPERNUS PHARMACEUTICALS, INC

Application No.: 11/889963   Filing Date: 17/Aug/2007

Abstract:

A pharmaceutical composition of a pharmaceutically acceptable trospium salt, with upon administration to a human patient generates an average steady state blood levels of trospium with a minimum (Cmin) and maximum (Cmax) blood levels of about 0.5-2.5 ng/ml and about 2.0-6.0 ng/ml, respectively.

Priority: US2004-980818 Applic. Date: 2004-11-04; US20030517198P Applic. Date: 2003-11-04; US20030523968P Applic. Date: 2003-11-21

Inventor: KIDANE ARGAW [US]; FLANNER HENRY H [US]; BHATT PADMANABH [US]; RAOUFINIA ARASH [US]


Application No.: US20080207677A1  Published: 28/Aug/2008

Title: Napthyridine Compounds As Rock Inhibitors

Applicant/Assignee: GPC BIOTECH AG

Application No.: 11/813236   Filing Date: 02/Jan/2006

Abstract:

The present invention relates to compounds having a naphthyridine scaffold, and stereoisomeric forms, prodrugs, solvates, hydrates and/or pharmaceutically acceptable salts of these compounds as well as pharmaceutical compositions containing at least one of these naphthyridine derivatives together with pharmaceutically acceptable carrier, excipient and/or diluents. Said naphthyridine compounds have been identified as inhibitors of the protein kinase ROCK2, also known as Rho-kinase, and are useful for the treatment of cancers (tumor growth and metastases), erectile dysfunction, cardiovascular diseases, hypertension, angina pectoris, cerebral ischaemia, cerebral vasospasm, myocardial ischaemia, coronary vasospasm, heart failure, myocardial hypertrophy, atherosclerosis, restenosis, spinal cord injuries, neuronal degeneration, thrombotic disorders, asthma, glaucoma, inflammation, anti-viral diseases (e.g. HIV), and osteoporosis.

Priority: EP20040031078 Applic. Date: 2004-12-31; WO2006EP50005 Applic. Date: 2006-01-02

Inventor: MULLER STEFAN [DE]; SCHWAB WILFRIED [DE]; KLEBL BERT [DE]; HAFENBRADL DORIS [DE]; HOPPE EDMUND [DE]; HORVATH ZOLTAN [HU]; KERI GYORGY [HU]; VARGA ZOLTAN [HU]; ORFI LASZLO [HU]; MAROSFALVI JENO [HU]; MULLER GERHARD [DE]


Application No.: US20080207734A1  Published: 28/Aug/2008

Title: Novel alkoxylactones, alkoxylactams and alkoxythiolactams for controlling processes based on microbial interaction

Applicant/Assignee: HENKEL AG & CO. KGAA

Application No.: 11/473795   Filing Date: 22/Jun/2006

Abstract:

Compounds of the Formula I, wherein A1 is O or NH

A2 is O or S

each of R1 and R2 is independently hydrogen, a methyl or C2-C8-saturated or mono- or doubly unsaturated, branched or linear hydrocarbon group

and R3 is a C1-C18-saturated or mono- or doubly unsaturated, branched or linear hydrocarbon group wherein, each of R1, R2 and R3 comprises a heteroatom selected from the group consisting of O and S in the chain and/or is mono- or multiply-substituted by a substituent selected from the group consisting of halogen, hydroxy, C1-C6-alkyl, trifluoromethyl, C1-C6-alkoxy, C6-C10-aryl, and C1-C6-alkyl-C6-C10-aryl are useful for controlling the interaction process between microorganisms such as in the development and/or maturation of biofilms

multicellular swarm behavior

the concerted development of antibiotic resistances

the concerted synthesis of antibiotics

the concerted synthesis of pigments

the concerted production of extracellular enzymes

or the concerted production of virulence factors.

Priority: DE20031061457 Applic. Date: 2003-12-23; WO2004EP14141 Applic. Date: 2004-12-11

Inventor: STUMPE STEFAN [DE]; BREVES ROLAND [DE]; HUCHEL URSULA [DE]; JANSSEN FRANK [DE]; HATZELT ANDRE [DE]


Application No.: US20080207754A1  Published: 28/Aug/2008

Title: Method and apparatus for palatable prevention of acid reflux

Applicant/Assignee:

Application No.: 12/072909   Filing Date: 28/Feb/2008

Abstract:

A method and applicators for preventing or reducing acid reflux (or "GERD") by delivering a proper dose of vinegar directly to the back of the throat without exposing the taste buds, and immediately followed by a shot of water or other pleasant tasting chaser to wash it down. One applicator generally comprises a joined pair of sealed flexible pouches each sealed by a seal that may be burst open on the application of pressure to the pouches in order to dispense the product therein. The first pouch is filled with a dose of undiluted apple cider vinegar (approximately 5 to 10 cc) and the second pouch is filled with a liquid chaser, usually distilled water. Another applicator generally comprises a drinking vessel defined by two side-by-side receptacles, and pair of fixedly attached straws each entering a corresponding receptacle. The straw entering the chaser is oriented at a fixed angle greater than the straw entering the vinegar so that vinegar pours first followed by the chaser. In use, the vessel is lifted to the mouth with both straws disposed at the back of the throat, and the vessel is tilted so that the vinegar receptacle pours first, followed immediately by the chaser. This results in the vinegar pouring directly down the throat without exposing the taste buds, and being immediately followed by the chaser to wash it down.

Priority: US20070903949P Applic. Date: 2007-02-28

Inventor: ZICKER WILLIAM A [US]


Application No.: US20080208340A1  Published: 28/Aug/2008

Title: Synthetic bone graft

Applicant/Assignee:

Application No.: 12/071756   Filing Date: 26/Feb/2008

Abstract:

A particulate glass for a synthetic bone (including dental) graft includes ZnO, SrO, and may include NaO. The glass promotes cellular metabolism, and upon implantation in living bone tissue induces bone growth at their surface. The ZnO and SrO respectively degrade to provide Zn<2+> and Sr<2+> ions respectively. The ions released by the glass provide anti-bacterial effects

improved bone formation in place of diseased tissue

inhibition of bone resorption

and radiopacity. There is excellent synergy between the SrO, ZnO, and NaO. The Sr<2+> ions have better bone formation effects than the Zn<2+> ions, but an anti-bacterial effect which is not as good. Choice of relative proportions of ZnO and SrO combined with the choice of NaO concentration to set the resorption rate allow optimisation. NaO there is control of the degradation rate of the graft

a feature which is advantageous in tailoring the grafts to specific patients and applications. Additionally the sodium (Na) in the glass imparts water solubility, allowing glasses to degrade to their ionic components.

Priority: US20070903316P Applic. Date: 2007-02-26

Inventor: BOYD DANIEL [IE]; TOWLER MARK ROBERT [IE]


Application No.: US20080209857A1  Published: 04/Sep/2008

Title: Process For Sterile Packaging of Containers With Drop-Dispensers, and Means For Actuating the Process

Applicant/Assignee: BORMIOLI ROCCO & FIGLIO S.P.A

Application No.: 10/566256   Filing Date: 13/Jan/2005

Abstract:

The process includes a stage of sterilisation of the flagon, the drop-dispenser and the closure cap making up the container, which is preceded by a stage in which the cap and the drop-dispenser are removably anchored together. In a subsequent stage the flagon and the drop-dispenser-cap group are placed in an aseptic environment, and the flagon is filled before the pre-assembled drop-dispenser-cap group is inserted on the flagon. The means for actuating the above process comprise a flagon ( 1 ), a drop-dispenser ( 2 ) which is pressure-inserted in the flagon ( 1 ) and a closure cap ( 3 ) which is screwed onto the drop-dispenser before the drop-dispenser ( 2 ) is inserted on the flagon ( 1 )

Priority: WO2005IT00012 Applic. Date: 2005-01-13

Inventor: MORINI EMILIO [IT]


Application No.: US20080210582A1  Published: 04/Sep/2008

Title: INHIBITION OF PAINT-PRODUCT SKIN FORMATION

Applicant/Assignee: THE SHERWIN-WILLIAMS COMPANY

Application No.: 12/039958   Filing Date: 29/Feb/2008

Abstract:

Paint in a container is inhibited against skinning by providing a layer of a barrier material comprising an inhibiting composition having a boiling point of at least 250 DEG C. and optionally water on the upper surface the bulk paint in the container.

Priority: US20070892685P Applic. Date: 2007-03-02

Inventor: BETZ DONALD LEE [US]; CAMERON JAMES MICHAEL [US]; GRAFF NORBERT ERWIN [US]


Application No.: US20080210707A1  Published: 04/Sep/2008

Title: Dispensing spout

Applicant/Assignee: POUR-ALL TECHNOLOGIES LTD

Application No.: 12/072861   Filing Date: 28/Feb/2008

Abstract:

A dispensing spout for dispensing pourable contents from a package is described. The spout comprises a shaft having a mouth at its distal end and a flange extending radially around an aperture at its proximal end. The spout is characterized by the flange having an adhesive layer upon its underside for retrofitting the spout to an outer surface of the package. Pourable contents are dispensable from the package in a controlled manner after puncturing the surface of the dispensable package through the aperture.

Priority: IL20070181657 Applic. Date: 2007-03-01

Inventor: KITAI AVNER [IL]


Application No.: US20080213192A1  Published: 04/Sep/2008

Title: AEROSOL LOTION FORMULATIONS

Applicant/Assignee: SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC

Application No.: 11/769482   Filing Date: 27/Jun/2007

Abstract:

Non-foaming aqueous emulsion compositions

methylparaben-based preservative systems for aqueous aerosol compositions having a pH at or above a pH where methylparaben begins to hydrolyze

cosmetic, household, and human and veterinary pharmaceutical products containing these compositions.

Priority: US20060816955P Applic. Date: 2006-06-27

Inventor: SCHLESINGER MARCIA S [US]; MANLEY DAVID SCOTT [US]; GRAHAM HEIDI N [US]


Application No.: US20080213194A1  Published: 04/Sep/2008

Title: Rhamnolipid-based formulations

Applicant/Assignee:

Application No.: 11/881271   Filing Date: 26/Jul/2007

Abstract:

The present invention relates to rhamnolipid-based formulations to clean, disinfect, deodorize, and act as an antimicrobial and antifungal agent for living and working environments. In addition, the present invention relates to the use of rhamnolipids to create a bio-film when applied to a surface, which prevents the growth of bacteria and fungus. This technique is especially useful to create clean surface areas for medical procedures, chemical testing, during food preparation, as well as for daycare centers and hospitals.

Priority: US20060820528P Applic. Date: 2006-07-27; US20060822461P Applic. Date: 2006-08-15; US20060864735P Applic. Date: 2006-11-07

Inventor: DESANTO KEITH [US]


Application No.: US20080213196A1  Published: 04/Sep/2008

Title: ENZYME CONTAINING COMPOSITION, PROCESS OF PRODUCING SAID COMPOSITION AND ITS USE

Applicant/Assignee: 3M ESPE AG

Application No.: 12/122027   Filing Date: 16/May/2008

Abstract:

The present invention relates to a composition comprising at least one biologically active protease and at least one biologically active glycosidase wherein the proteases and the glycosidases are present in an activity ratio of from 1,000,000:1 to 1:1,000,000 and wherein the composition has a total enzyme activity of at least 2 U/ml. Furthermore, the present invention relates to a process of producing such enzyme comprising composition and to processes of removing caries. Moreover, the invention relates to the use of one or more enzyme comprising compositions for producing a treatment agent for removing caries.

Priority: DE20021037317 Applic. Date: 2002-08-15; US2005-525294 Applic. Date: 2005-09-22; WO2003EP05183 Applic. Date: 2003-05-16

Inventor: HABERLEIN INGO [DE]; GUGGENBERGER RAINER [DE]; WEINMANN WOLFGANG [DE]; KAPPLER OLIVER [DE]


Application No.: US20080213325A1  Published: 04/Sep/2008

Title: POWDER MIXTURE CONSISTING OF TITANIUM DIOXIDE, ZINC OXIDE AND ZINC/TITANIUM MIXED OXIDE

Applicant/Assignee: DEGUSSA AG

Application No.: 12/100746   Filing Date: 10/Apr/2008

Abstract:

A powder mixture consisting of zinc/titanium mixed oxide particles, titanium dioxide particles and zinc oxide particles, wherein the zinc/titanium mixed oxide particles have a composition according to the formula (ZnO)1-x(TiO2)x, where 0.01

Priority: DE20021059860 Applic. Date: 2002-12-20; US2005-530708 Applic. Date: 2005-04-08; WO2003EP13923 Applic. Date: 2003-12-09

Inventor: SCHUMACHER KAI [DE]; HASENZAHL STEFFEN [DE]; MOERTERS MARTIN [DE]


Application No.: US20080213359A1  Published: 04/Sep/2008

Title: Calcium sulfate based nanoparticles

Applicant/Assignee: THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

Application No.: 12/011930   Filing Date: 30/Jan/2008

Abstract:

The present invention provides a method for facilitating repair of an area of bone by providing hemihydrate calcium sulfate particles, mixing the particles with an aqueous solution to obtain a paste, applying the paste to an area of bone in need of repair, and allowing the paste to set.

Priority: US20070887184P Applic. Date: 2007-01-30; US20070887859P Applic. Date: 2007-02-02

Inventor: PARK YOUNGBUM [US]; DZIAK ROSEMARY [US]; GENCO ROBERT J [US]; SWIHART MARK [US]; PERINPANAYAGAM HIRAN [CA]


Application No.: US20080213719A1  Published: 04/Sep/2008

Title: Temperature Modified Oral Cleaning Device

Applicant/Assignee:

Application No.: 12/014021   Filing Date: 14/Jan/2008

Abstract:

A temperature modified oral care device including a base

an electrical circuit disposed at least partially in said base

and, a heating element connected to the electrical circuit.

Priority: US20070884620P Applic. Date: 2007-01-12

Inventor: GINIGER MARTIN S [US]; HANSON ROWLAND [US]


Application No.: US20080213726A1  Published: 04/Sep/2008

Title: Dental Implant and Method for the Production Thereof

Applicant/Assignee: THOMMEN MEDICAL AG

Application No.: 11/916749   Filing Date: 01/Jun/2006

Abstract:

The invention relates to a ceramic implant, especially a dental implant, comprising a structured or porous surface for at least partially inserting into a bone. An especially advantageous surface is obtained when it is at least partially modified by a salt melt. These excellent osteointegration properties can be obtained by a method whereby the surface is modified in a salt melt at least in the regions exposed to the bones and/or soft tissue, optionally following a previous modification of the surface whereby material has been removed.

Priority: CH20050000947 Applic. Date: 2005-06-06; WO2006CH00296 Applic. Date: 2006-06-01

Inventor: SCHLOTTIG FALKO [CH]; HEFTI THOMAS [CH]


Application No.: US20080213727A1  Published: 04/Sep/2008

Title: Graded glass/ceramic/glass structures for damage resistant ceramic dental and orthopedic prostheses

Applicant/Assignee:

Application No.: 11/986290   Filing Date: 20/Nov/2007

Abstract:

The present invention provides a functionally graded glass/ceramic/glass sandwich system especially useful in damage resistant, ceramic dental and orthopedic prosthesis. The functionally graded glass/substrate/glass composite structure comprises an outer (aesthetic) residual glass layer, a graded glass-ceramic layer, and a dense interior ceramic. The functionally graded glass/substrate/glass composite structure may further comprise a veneer on an exterior surface. The present invention also provides a method for preparing a functionally graded glass/ceramic/glass sandwich system. A powdered glass-ceramic composition or a glass tape is applied to the accessible surfaces of a dense alumina substrate to thereby substantially cover the substrate surfaces. The glass of the composition has a CTE similar to that of the substrate material. The glass-ceramic composition is infiltrated into the dense substrate by heating the assembly to temperatures 50-700 DEG C. below the sintering temperature of the substrate.

Priority: US20060860165P Applic. Date: 2006-11-20

Inventor: ZHANG YU [US]; KIM JAE-WON [US]; THOMPSON VAN P [US]


Application No.: US20080213729A1  Published: 04/Sep/2008

Title: METHOD AND APPARATUS FOR PERFORMING MAXILLARY SINUS ELEVATION

Applicant/Assignee:

Application No.: 12/102085   Filing Date: 14/Apr/2008

Abstract:

A method and apparatus is disclosed for providing implants in the upper jaws of a person. A sleeve is inserted through the alveolar ridge to the maxillary sinus. The sleeve is used to raise the subantral membrane and form a cavity. A filler, such as a bone growth stimulant is injected through the sleeve into the cavity. In the process, the sleeve also can cut and/or condense the bone around itself so that the bone can hold an implant. Optionally, the bone growth stimulant is also introduced into the bone surrounding the sleeve. During the injection, the pressure within the sleeve or the cavity is monitored to detect and prevent the rupture of the subantral membrane.

Priority: US2005-227687 Applic. Date: 2005-09-15; US20040619542P Applic. Date: 2004-10-15

Inventor: HOCHMAN MARK N [US]


Application No.: US20080213730A1  Published: 04/Sep/2008

Title: TOOTH WHITENING DENTAL TRAY AND METHOD OF USE

Applicant/Assignee: COLGARE-PALMOLIVE COMPANY

Application No.: 12/105065   Filing Date: 17/Apr/2008

Abstract:

A dental tray with a hydrophobic tooth whitening formulation where the tooth whitening formulation is substantially non-water soluble, and a method of using this dental tray to whiten the teeth. The tooth whitening formulation is primarily comprised of a hydrophobic polymer and a peroxide or a peroxide yielding compound. Preferably the hydrophobic polymer is the condensation product of a silicone resin and an organosiloxane. The dental tray is formed to encompass the front and the rear surfaces of the teeth. The dental tray is comprised of a thermoplastic or thermoset polymer. The teeth whitening formulation is placed into the dental tray and the tray placed against the teeth to be whitened. This is for a sufficient period of time to at least partially whiten teeth. This can be a period of time from about 0.5 hour to 2 hours or more. The substantially non-aqueous tooth whitening formulation is effective over a longer period of time since it is not significantly diluted or removed from the dental tray during the treatment time.

Priority: US2004-754065 Applic. Date: 2004-01-07; US2003-642458 Applic. Date: 2003-08-15

Inventor: PRENCIPE MICHAEL [US]; CHOPRA SUMAN K [US]; COLLINS MICHAEL [US]


Application No.: US20080214530A1  Published: 04/Sep/2008

Title: Photo-Activated Disinfection

Applicant/Assignee:

Application No.: 10/558026   Filing Date: 21/May/2004

Abstract:

The present invention relates to photo-activated disinfection. In particular, the present invention relates to photo-activated disinfection in the oral cavity. We describe a dental apparatus comprising a light source producing light at a predetermined wavelength and power, and optical transmission means to train the light from the light source onto at least one external side of a tooth. Preferably, the optical transmission means comprises at least one optical guide. In a preferred embodiment, the optical transmission means comprises a pair of substantially parallel elongate light guides each light guide having a distal end provided with a reflective surface inclined at 45 DEG to the direction of light transmission along the light guides, the reflective surfaces of the light guides being opposed such that light emitted from each light guide is parallel but opposite in direction. Preferably, the light source is a light emitting diode or array of light emitting diodes and the has a wavelength of from 550 to 690 nm, more preferably from 600 nm to 680 nm, even more preferably from 625 to 660 nm.

Priority: GB20030011950 Applic. Date: 2003-05-23; WO2004GB02187 Applic. Date: 2004-05-21

Inventor: COLLES MICHAEL JOHN [GB]


Application No.: US20080214691A1  Published: 04/Sep/2008

Title: Low-viscosity allophanates containing actinically curable groups

Applicant/Assignee:

Application No.: 12/072022   Filing Date: 22/Feb/2008

Abstract:

A process for preparing binders containing allophanate groups which contain, at the oxygen atom of the allophanate group that is bonded via two single bonds, organic radicals with activated groups capable of participating in a polymerization reaction with ethylenically unsaturated compounds on exposure to actinic radiation

the process includes reacting A) one or more compounds containing uretdione groups with B) one or more OH-functional compounds which contain groups capable of participating in a polymerization reaction with ethylenically unsaturated compounds on exposure to actinic radiation, and C) optionally further NCO-reactive compounds, and D) in the presence of one or more compounds containing phenoxide groups, as catalysts. The binders can be used in preparing coatings, coating materials, coating compositions, adhesives, printing inks, casting resins, dental compounds, sizes, photoresists, stereolithography systems, resins for composite materials and sealants.

Priority: DE200410012903 Applic. Date: 2004-03-17; US2005-080706 Applic. Date: 2005-03-14

Inventor: DETREMBLEUR CHRISTOPHE [BE]; WEIKARD JAN [DE]; GRESZTA-FRANZ DOROTA [DE]; RICHTER FRANK [DE]; FISCHER WOLFGANG [DE]; SCHMITZ JORG [DE]; MUNDSTOCK HOLGER [DE]


Application No.: US20080214820A1  Published: 04/Sep/2008

Title: Enantiomers of 3-Heteroaryl-8H-8-Azabicyclo (3.2.1) Oct-2-Ene and their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee: NEUROSEARCH A/S

Application No.: 11/793137   Filing Date: 15/Dec/2005

Abstract:

This invention relates to novel enantiomers useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20040001950 Applic. Date: 2004-12-17; DK20050000506 Applic. Date: 2005-04-08; US20040636869P Applic. Date: 2004-12-20; US20050669887P Applic. Date: 2005-04-11; WO2005EP56801 Applic. Date: 2005-12-15

Inventor: PETERS DAN [SE]; BROWN DAVID TRISTRAM [DK]; EGESTAD BORJE [DK]; DAM EVA [DK]; JONES DAVID SPENCER [DK]; FROSTRUP BRIAN [DK]; NIELSEN ELSEBET OSTERGAARD [DK]; OLSEN GUNNAR M [DK]; REDROBE JOHN PAUL [DK]


Application No.: US20080215010A1  Published: 04/Sep/2008

Title: APPARATUS AND METHOD FOR USING AN INTRAOSSEOUS SPACE FOR MOVING FLUID INTO AND OUT OF THE BODY

Applicant/Assignee:

Application No.: 11/941961   Filing Date: 18/Nov/2007

Abstract:

An apparatus for communication between a site within a body and a source, depot, reservoir, device or machine external to the body via the mouth of the body, comprising an implant for placement in tooth-supporting bone, the implant having a first portion extending into the mouth external to the tooth-supporting bone, a second portion for being embedded in the tooth-supporting bone, and an opening extending along the implant from the first portion to the second portion. A sealing cap containing an antimicrobial substance may be provided to provide a seal when the apparatus is not in use. An external pump may infuse various medications or liquids, including those required by a person having a diabetic condition.

Priority: US2005-068508 Applic. Date: 2005-02-28; US20040548045P Applic. Date: 2004-02-26; US20060859775P Applic. Date: 2006-11-17

Inventor: SILVER THEODORE A [US]; WOOD DAVID J [US]


Application No.: US20080216257A1  Published: 11/Sep/2008

Title: TOOTHBRUSH HAVING A PLURALITY OF REPLACABLE HEADS CONFIGURED TO CLEAN A PLURALITY OF ORAL SURFACES SIMULTANEOUSLY

Applicant/Assignee:

Application No.: 11/684322   Filing Date: 09/Mar/2007

Abstract:

A toothbrush has a plurality of replaceable cleaning heads configured to clean a plurality of teeth surfaces simultaneously. The cleaning heads may be configured to clean one row of teeth at a time or bottom and top teeth simultaneously. In a configuration for cleaning bottom and top teeth simultaneously, the cleaning heads for the top teeth are movably offset from the cleaning heads for the bottom teeth to accommodate occlusion. The toothbrush may be manual or electrical. Accessories such as a tongue and cheek scraper and tooth pick are available.

Priority:

Inventor: AHADPOUR MITRA [US]; BAGHERI FARHAD [US]


Application No.: US20080216322A1  Published: 11/Sep/2008

Title: Cartridge for an Appliance for Personal Care and an Appliance Comprising Such a Cartridge

Applicant/Assignee: KONINKLIJKE PHILIPS ELECTRONICS N.V

Application No.: 11/917895   Filing Date: 06/Jun/2006

Abstract:

A cartridge for an appliance for personal care, such as skin, dental or hair treatment includes a main body ( 2 ), a dispensing structure ( 3, 11, 12 ) for dispensing a substance, such as a liquid, a paste or a gel, and a cartridge ( 3 ) detachably connected to the main body ( 2 ). The cartridge bounds a reservoir space ( 5 ) for holding the substance to be dispensed and includes: a flexible wall part ( 7 ) bounding the reservoir space ( 5 ) for allowing reservoir space ( 5 ) volume to accommodate to a volume of the substance filled therein and volumes of the substance dispensed therefrom

a rigid wall part ( 16 ) also bounding the reservoir space ( 5 ), and a rigid housing ( 6, 14 ). The flexible wall part ( 7 ) is connected to the rigid housing ( 6, 14 ) along a contour ( 23 ) of the rigid wall part ( 16 ).

Priority: EP20050105295 Applic. Date: 2005-06-16; WO2006IB51799 Applic. Date: 2006-06-06

Inventor: MOLEMA JEROEN [NL]; WESTERHOF WILKO [NL]; SINNEMA ANKE [NL]; BLAAK JOHANNES JOSEPHUS [NL]


Application No.: US20080219776A1  Published: 11/Sep/2008

Title: CONNECTING PROFILE FOR INTERCONNECTING THREE SHEET PILE WALL COMPONENTS AND AN ARRANGEMENT OF SHEET PILE WALL COMPONENTS COMPRISING SUCH A CONNECTING PROFILE

Applicant/Assignee: PILEPRO LLC

Application No.: 12/028705   Filing Date: 08/Feb/2008

Abstract:

A connecting profile is disclosed for interconnecting three sheet-pile wall components. The connecting profile has a basic body from which three identical lock profiles project in predetermined coupling directions. Each lock profile comprises a thumb strip with a central web on which is formed a thumb which extends transversely to the longitudinal direction of the central web. A curved finger strip points in the direction of the thumb strip and forms a lock inner chamber and defines a mouth opening for the lock of the sheet-pile wall component that is to be hooked in. The mouth opening and the lock inner chamber are designed in such a way that the lock of the sheet-pile wall component that is to be hooked into the lock profile can be pivoted in the lock profile by a pivot angle of at least 15 degrees.

Priority: DE200510037564 Applic. Date: 2005-08-09; DE200610000624 Applic. Date: 2006-01-02; WO2006EP07208 Applic. Date: 2006-07-21

Inventor: HEINDL RICHARD [DE]; WENDT ROB [US]


Application No.: US20080220026A1  Published: 11/Sep/2008

Title: Mesoporous material compositions and methods of their use for improving the appearance of biological surfaces

Applicant/Assignee:

Application No.: 11/714516   Filing Date: 06/Mar/2007

Abstract:

The present invention relates to compositions and methods for treating and improving the aesthetic appearance of a biological surface by altering the optical properties of the biological surface, thereby resulting in a natural appearance. The compositions of the invention may be topically applied to the biological surface, including but not limited to skin, in an amount effective in improving the aesthetic and natural appearance of the biological surface.

Priority:

Inventor: MAITRA PRITHWIRAJ [US]; BRAHMS JOHN C [US]


Application No.: US20080220032A1  Published: 11/Sep/2008

Title: ORAL CARE LAYER AND RELATED METHOD OF MANUFACTURE

Applicant/Assignee: RANIR, LLC

Application No.: 12/043743   Filing Date: 06/Mar/2008

Abstract:

An oral care composition including a hydrophilic, aliphatic, polyether-based thermoplastic polyurethane, a glycol polymer, and a poly(N-vinyl lactam). These components form a tacky film having a thickness of about 1 mils to about 50 mils. A whitening agent, such as a peroxide, can be absorbed into the tacky film, and adapted to desorb from the tacky film to whiten teeth to which the film is joined. A method is also provided in which the components are extruded through a twin screw extruder and output to a die to produce the film. The whitening agent can be deposited on the film and absorbed by the film to form a relatively stable oral care composition including the whitening agent.

Priority: US20070893296P Applic. Date: 2007-03-06

Inventor: SHAH KISHORE R [US]; PETROCELLI RAYNOLD M [US]; FISHER JEFFREY J [US]


Application No.: US20080220037A1  Published: 11/Sep/2008

Title: Biphosphonic Compounds For Preventing Or Limiting Fixing Of Macromolecules, Microorganisms And Biofilm On Solid, In Particular Metal Or Mineral Surfaces

Applicant/Assignee: SURFACTIS TECHNOLOGIES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M UNIVERSITE D'ANGERS

Application No.: 11/791291   Filing Date: 21/Nov/2005

Abstract:

The invention concerns biphosphonic compounds of formula (I)

microbiological anti-contamination compositions containing same, and their use for preventing or limiting fixing of macromolecules, micro-organisms and biofilm on solid surfaces, such as metal or mineral surfaces.

Priority: FR20040012358 Applic. Date: 2004-11-22; WO2005EP56120 Applic. Date: 2005-11-21

Inventor: DENIZOT BENOIT [FR]; HINDRE FRANCOIS [FR]; PORTET DAVID [FR]


Application No.: US20080220103A1  Published: 11/Sep/2008

Title: METHOD FOR TREATING/CONTROLLING/KILLING FUNGI AND BACTERIA ON LIVING ANIMALS

Applicant/Assignee:

Application No.: 12/047992   Filing Date: 13/Mar/2008

Abstract:

Provided is a method of treating a fungal infection on an animal epidermis, nail or hair, or in an orifice of an animal. The method comprises contacting the fungus infection with a composition comprising an antifungal botanical.

Priority: US2006-541822 Applic. Date: 2006-10-02; US20050729624P Applic. Date: 2005-10-24

Inventor: BIRNBAUM JAY [US]; BLAKE THOMAS [US]; GHANNOUM MAHMOUD [US]; VALLESPIR STEVEN [US]


Application No.: US20080220394A1  Published: 11/Sep/2008

Title: Deposition of discrete nanoparticles on a nanostructured surface of an implant

Applicant/Assignee: BIOMET 3I, INC

Application No.: 11/977351   Filing Date: 24/Oct/2007

Abstract:

A method of forming an implant to be implanted into living bone is disclosed. The method comprises the act of roughening at least a portion of the implant surface to produce a microscale roughened surface. The method further comprises forming a nanoscale roughened surface on the microscale roughened surface. The method further comprises the act of depositing discrete nanoparticles on the nanoscale roughened surface though a one-step process of exposing the roughened surface to a solution including the nanoparticles. The nanoparticles comprise a material having a property that promotes osseointegration.

Priority: US20060854027P Applic. Date: 2006-10-24

Inventor: BERCKMANS BRUCE [US]; TOWSE ROSS W [US]; MAYFIELD ROBERT L [US]


Application No.: US20080220396A1  Published: 11/Sep/2008

Title: Methods for making dental restorations using two-phase light-curing materials

Applicant/Assignee:

Application No.: 12/072263   Filing Date: 25/Feb/2008

Abstract:

Methods for making dental crowns, bridges, inlays, onlays, veneers, fillings, and other restorations are provided. The methods involve using a two-phase light curing (TPLC) material. Preferably, the TPLC material used to form the dental restoration comprises a blend of polymerizable compounds

photopolymerization systems (a) and (b), and particulate filler materials (a) and (b). In a first light-curing step, curing light having a wavelength of greater than 420 nm is used to activate system (a). In a second light-curing step, curing light having a wavelength of less than 420 nm is used to activate system (b). The two step light-curing method is efficient and allows the dentist to make restorations having high mechanical strength and pleasing aesthetics.

Priority: US20070903089P Applic. Date: 2007-02-23

Inventor: SUN FUMING [US]


Application No.: US20080221123A1  Published: 11/Sep/2008

Title: Piperazinone Compounds as Anti-Tumor and Anti-Cancer Agents and Methods of Treatment

Applicant/Assignee: YALE UNIVERSITY UNIVERSITY OF SOUTH FLORIDA

Application No.: 10/484560   Filing Date: 23/Aug/2002

Abstract:

The present invention relates to piperazinone compounds, pharmaceutical compositions containing those compounds and methods of treating tumors and cancer, among other disease states and conditions in mammalian patients, especially including humans.

Priority: US20010314795P Applic. Date: 2001-08-24; WO2002US26881 Applic. Date: 2002-08-23

Inventor: HAMILTON ANDREW D [US]; SEBTI SAID [US]; PENG HAIRUO [US]


Application No.: US20080221404A1  Published: 11/Sep/2008

Title: MULTIFUNCTION HEALTH APPARATUS

Applicant/Assignee:

Application No.: 12/122085   Filing Date: 16/May/2008

Abstract:

The present invention provides a multifunction health device, which comprises a meter and a platform. The meter has two electrodes arranged separately at its two sides or both arranged at its one side, and the meter has another electrode arranged in its bottom. The platform has four electrodes arranged in its top face, and a pressure sensor arranged in its inside. With or without some parts assisting, the single use of the meter can function as an ECG detector, a TENS machine, a thermometer, and a first sphygmomanometer. Connecting with the platform, the meter and the platform can function as an ECG detector, a weight scale, and a body composition estimator. Further, the meter can alternatively connect with a chassis thus functioning as a second sphygmomanometer, a stethoscope, a glucose meter, or a pulse oximeter.

Priority: US2006-598128 Applic. Date: 2006-11-13

Inventor: TSO SHUN-WUN [TW]


Application No.: US20080221688A1  Published: 11/Sep/2008

Title: Method of Maintaining Fatigue Performance In A Bone-Engaging Implant

Applicant/Assignee: WARSAW ORTHOPEDIC, INC

Application No.: 11/684135   Filing Date: 09/Mar/2007

Abstract:

This disclosure is directed to a method capable of maintaining the fatigue performance of a bone-engaging implant after surface texturing through the imparting of a residual compressive stress. A residual compressive stress is imparted via peening or another process. The peened surface is then roughened to improve mechanical adhesion for bone fixation via grit blasting or another process. The depth of penetration of the roughened texture is less than the depth of the residual compressive stress.

Priority:

Inventor: TRIEU HAI H [US]; BONO FRANK [US]


Application No.: US20080222837A1  Published: 18/Sep/2008

Title: Compact vacuum cleaning device

Applicant/Assignee:

Application No.: 11/906515   Filing Date: 02/Oct/2007

Abstract:

A compact vacuum cleaning device for automatic cleaning of smooth and textile floor coverings, particularly in the private home sector, has a housing, a suction mouth on the underside of the housing, a cleaning roller disposed in a roller chamber, a dust collection container, a suction fan, an electrical travel drive, control electronics, and a power source. The device height of the vacuum cleaning device is less than 180 mm. The maximal suction air stream that enters through the suction mouth, passes through the dust collection container, and leaves the vacuum cleaning device through the suction fan, is greater than 15 l/s. The maximal suction power is greater than 10 W.

Priority: EP20060022038 Applic. Date: 2006-10-20

Inventor: KAFFENBERGER DIETER [DE]; DILGER HORST [DE]; RIEHL KLAUS-DIETER [DE]


Application No.: US20080223003A1  Published: 18/Sep/2008

Title: Machine For Packing Stacks Of Disc-Shaped Articles Inside Rigid Cylindrical Containers

Applicant/Assignee: MARCHESINI GROUP S.P.A

Application No.: 12/041251   Filing Date: 03/Mar/2008

Abstract:

The machine of the invention for packing tablets inside rigid tubes exhibits: a supply line for supplying empty tubes arranged with vertical axes and mouths facing upwards

an inlet station wherein deflector organs operate which tip the cylindrical containers on sides thereof, and first organs which pick up individual thus-tipped containers and release the containers to corresponding gripping organs provided by a multiple conveyor

a filling station in which a plurality of supply units release a predetermined quantity of tablets, stacked one on the other, into paused tubes, borne by the multiple conveyor

a closing station containing means which insert caps into the mouths of the filled containers borne by the multiple conveyor

an outlet station containing means which pick up paused individual closed containers borne by the multiple conveyor and release the containers onto transporter organs.

Priority: IT2007BO00176 Applic. Date: 2007-03-14

Inventor: MONTI GIUSEPPE [IT]


Application No.: US20080226613A1  Published: 18/Sep/2008

Title: Prognosis, diagnosis and treatment of bone marrow derived stem cell associated cancer

Applicant/Assignee: UNIVERSITY OF MASSACHUSETTS

Application No.: 12/069072   Filing Date: 07/Feb/2008

Abstract:

The present invention is based on the unexpected discovery that the loss of cells in inflamed tissue during chronic inflammation leads to the influx and long-term re-population of the tissue with bone marrow derived stem cells, and that it is these stem cells that are the primary source of metaplasia and cancer. Accordingly, the invention relates to various methods, reagents and kits for prognosing, diagnosing, staging, monitoring, preventing and treating cancers, particularly cancers associated with chronic inflammation.

Priority: US2004-826082 Applic. Date: 2004-04-15; US20030464084P Applic. Date: 2003-04-18; US20030504576P Applic. Date: 2003-09-18

Inventor: WANG TIMOTHY C [US]; HOUGHTON JEANMARIE [US]


Application No.: US20080226728A1  Published: 18/Sep/2008

Title: Antimicrobial Nanoparticulate Additives Forming Non-Leachable Sustained Antimicrobial Polymeric Compositions

Applicant/Assignee:

Application No.: 11/794492   Filing Date: 01/Jan/2006

Abstract:

The present invention provides a particle comprising at least one aliphatic polymer having anti-microbially active quaternary ammonium groups chemically bound thereto. The particle of the invention may be used to inhibit populations of microorganisms and biofilms. Also provided are methods for the preparation of such particles and uses thereof for the inhibition of microorganisms.

Priority: US20040639966P Applic. Date: 2004-12-30; WO2006IL00005 Applic. Date: 2006-01-01

Inventor: DOMB ABRAHAM J [IL]; WEISS ERVIN [IL]; BEYTH NURIT [IL]; FARBER IRA [IL]; DAVIDI MICHAEL PEREZ [IL]


Application No.: US20080227046A1  Published: 18/Sep/2008

Title: SYSTEMS, METHODS, AND ADJUNCTIVE PROCEDURES FOR CORRECTING MALOCCLUSION

Applicant/Assignee:

Application No.: 11/773849   Filing Date: 05/Jul/2007

Abstract:

Methods of inducing tooth movement and treating malocclusion, craniofacial anomalies, bony defects, and dentofacial deformities through accelerated bone remodeling as caused by the delivery non-static forces

reducing pain and discomfort in patients

and improving tissue integrity long-term results as to prevent post-orthodontic treatment relapse. The methods and apparatus include a mechanism for data capture and analysis related to patient compliance and usage behavior, as well as for establishing the invention as a component of the clinical office workflow to increase efficiency and productivity.

Priority: US20070906807P Applic. Date: 2007-03-14

Inventor: LOWE MICHAEL KENNETH [US]; WASDEN CHRISTOPHER LYLE [US]; TARVER WILLIAM BRENT [US]


Application No.: US20080227049A1  Published: 18/Sep/2008

Title: Lingual Retainer

Applicant/Assignee:

Application No.: 11/997891   Filing Date: 06/Jul/2006

Abstract:

The invention relates to a retaining unit (lingual retainer) for Orthodontic treatment in particular for treating incisors ( 4 to 7 ) of lower and/or upper jaws, in particular for avoiding the return for formation a tertiary front overlapping by means of a tension element which is pasted (adhesive point 12 ) to each tooth ( 2 to 7 ) and forms a plastic shaped component ( 8 ) compatible with a mouth cavity.

Priority: DE200510036678 Applic. Date: 2005-08-04; WO2006EP06586 Applic. Date: 2006-07-06

Inventor: SEVINC HABIB [DE]


Application No.: US20080227052A1  Published: 18/Sep/2008

Title: Dose Delivery System

Applicant/Assignee:

Application No.: 10/598343   Filing Date: 25/Feb/2005

Abstract:

The present invention is directed to a unit dose delivery system for flowable substances. The delivery system or applicator of the present invention allows storage, mixing and well controlled dispensing of multi-material component substances.

Priority: EP20040004596 Applic. Date: 2004-02-27; EP20040005468 Applic. Date: 2004-03-08; EP20040005614 Applic. Date: 2004-03-09; WO2005EP02017 Applic. Date: 2005-02-25

Inventor: PEUKER MARC [DE]; HOHMANN ARNO [DE]; PAUSER HELMUT [DE]


Application No.: US20080230053A1  Published: 25/Sep/2008

Title: PULSE DRUG NEBULIZATION SYSTEMS, FORMULATIONS THEREFORE, AND METHODS OF USE

Applicant/Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

Application No.: 11/855870   Filing Date: 14/Sep/2007

Abstract:

Liquid nebulizer apparatus, systems, and formulation compositions, as well as systems for the nebulized, aerosol delivery of such compositions, for the administration and insufflation of medicinal aerosols into the pulmonary system of a mammal are described. The nebulizing apparatus and system can effectively aerosolize a variety of viscosities of medicinal liquid drug carriers, including those made up of oil, water, or emulsions of oil and water. Drugs dissolved or suspended in the compositions and formulations described and adapted for use herein are not damages or denatured by the nebulization process when the nebulizer described is used. Further, the nebulization system itself can be adapted for use with both mechanically assisted pulmonary ventilation systems as well as hand-held inhalers and nose/mouth face masks for use in pulmonary drug delivery.

Priority: US20060845087P Applic. Date: 2006-09-15; US20070891128P Applic. Date: 2007-02-22

Inventor: KRAFT EDWARD R [US]; ENKHBAATAR PERENLEI [US]; TRABER DANIEL L [US]; KULP GABRIELA A [US]


Application No.: US20080230298A1  Published: 25/Sep/2008

Title: Method of Applying Oral Compositions

Applicant/Assignee:

Application No.: 10/572272   Filing Date: 15/Sep/2004

Abstract:

A method of applying oral compositions to the temporary and permanent surfaces of the oral cavity comprising the step of obtaining a container and applicator combination formed as an assembly that comprises an internal region that contains an oral care composition and an externally projecting pair of spreadable wings, expelling said oral care composition from said internal region and spreading said oral care composition onto the surfaces of the oral cavity with said spreadable wings.

Priority: US20030504014P Applic. Date: 2003-09-18; WO2004US30273 Applic. Date: 2004-09-15

Inventor: BUCH ROBERT MICHAEL [US]; GAMBOGI ROBERT J [US]; HUIE PETER R [US]


Application No.: US20080230397A1  Published: 25/Sep/2008

Title: Process for the polishing of metallic dental prostheses

Applicant/Assignee: DEGUDENT GMBH

Application No.: 12/050307   Filing Date: 18/Mar/2008

Abstract:

The invention concerns a process for the polishing of metallic dental prostheses, such as frames. In order to reproducibly obtain a defined surface roughness with no need for additional finishing, it is proposed for the dental prosthesis to be polished by means of plasma polishing.

Priority: DE200710013638 Applic. Date: 2007-03-19

Inventor: FECHER STEFAN [DE]; HAIZMANN MARTIN [DE]; VOLKL LOTHAR [DE]; WEISENSEL LARS [DE]


Application No.: US20080231695A1  Published: 25/Sep/2008

Title: Device for dental operations

Applicant/Assignee: F.A.R.O. FABBRICA APPARECCHIATURE RAZIONALI ODONTOIATRICHE S.P.A

Application No.: 12/077339   Filing Date: 19/Mar/2008

Abstract:

A device for medical use and particularly for dental use, of which the main component is a rigid video-endoscope ( 10 ) supported by an articulated and compensated arm, comprises: a rigid video-endoscope ( 10 ) with CCD catcher ( 13 ), composed of a grip ( 11 ) which is extended into an optical tube ( 12 ) coaxial therewith, said optical tube ( 12 ) being made so to provide an image of the object examined on the plane of the CCD catcher ( 13 ), the imaging being directed in the extension of the axis ( 14 ) of the video-endoscope ( 10 )

a sleeve ( 32 ) which covers the optical tube ( 12 ) and which protects it from the risks of contamination during use, the sleeve ( 32 ) being coaxial with optical tube ( 12 ), freely rotatable on itself and lockable in the distal part of the grip ( 11 ) of the video-endoscope ( 10 ), between the sleeve ( 32 ) and the optical tube ( 12 ) an airspace being defined in which pressurized air is inserted

a compensated, articulated arm that bears, fixed to its distal end, a support on which the video-endoscope ( 10 ) is locked. According to the invention, the rotation and reflection of the image is obtained by means of an optical group composed of a first optical half-prism ( 16 ), a second optical half-prism ( 17 ) and a reflecting body ( 18 ) arranged on a rotating housing ( 19 ), actuated by a micromotor ( 22 ).

Priority: IT2007MI00544 Applic. Date: 2007-03-20

Inventor: FAVONIO ANGELO [IT]


Application No.: US20080232998A1  Published: 25/Sep/2008

Title: NON-MAGNETIC COBALT-PALLADIUM DENTAL ALLOY

Applicant/Assignee:

Application No.: 12/050006   Filing Date: 17/Mar/2008

Abstract:

A non-magnetic cobalt based "noble" metal dental alloy is provided. The alloy generally contains at least 25 wt. % palladium, from 15 to 30 wt. % chromium and a balance of cobalt, where to ensure the alloy is non-magnetic the concentration of chromium in the alloy is at least 20 wt. %, or if the concentration of chromium is less than 20 wt. % the combined concentration of chromium, molybdenum, tungsten, niobium, tantalum vanadium and rhenium is greater than 20 wt. %.

Priority: US20070896182P Applic. Date: 2007-03-21; US20070941908P Applic. Date: 2007-06-04; US20070978828P Applic. Date: 2007-10-10

Inventor: PRASAD ARUN [US]; CASCONE PAUL J [US]


Application No.: US20080233054A1  Published: 25/Sep/2008

Title: DENTAL ANTI-HYPERSENSITIVITY COMPOSITION AND METHOD

Applicant/Assignee: RESEARCH FOUNDATION OF STATE OF UNIVERSITY OF NEWYORK

Application No.: 11/836041   Filing Date: 08/Aug/2007

Abstract:

The present invention relates to compositions and methods for calcifying dental tissue, e.g., preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion.

Priority: US2002-328389 Applic. Date: 2002-12-23; US2001-940723 Applic. Date: 2001-08-27; US2000-504264 Applic. Date: 2000-02-15; US19990140560P Applic. Date: 1999-06-23

Inventor: KLEINBERG ISRAEL [US]; ACEVEDO ANA MARIE [VE]; CHATTERJEE ROBI [US]


Application No.: US20080233057A1  Published: 25/Sep/2008

Title: MILD CLEANSING COMPOSITIONS

Applicant/Assignee:

Application No.: 12/052262   Filing Date: 20/Mar/2008

Abstract:

Mild cleansing compositions comprising anionic, nonionic and/or amphoteric surfactants, one or more dyes having a total color, and one or more encapsulated dyes, including microencapsulated dyes, in microcapsules prepared by coacervation, precipitation, polycondensation or other reaction of anionic and cationic components, which encapsulated dyes have a total color different from the total color of the previous dye(s), plus, water, and, optionally, one or more additives and/or auxiliaries, which compositions are useful in personal care preparations, such as liquid soaps, hand-washing pastes, toothpastes, manual dishwashing preparations, and light-duty detergents.

Priority: EP20070005747 Applic. Date: 2007-03-21

Inventor: VILADOT PETIT JOSEP-LLUIS [ES]; DE MORAGAS MARIA [ES]; GOMEZ YOLANDA [ES]; ASENSIO JUAN-ANTONIO [ES]; MARTINEZ SILVIA [ES]; SANCHEZ AGUSTIN [ES]


Application No.: US20080233428A1  Published: 25/Sep/2008

Title: MECHANICAL PARTS HAVING INCREASED WEAR RESISTANCE

Applicant/Assignee: SKAFF CORPORATION OF AMERICA, INC

Application No.: 12/052990   Filing Date: 21/Mar/2008

Abstract:

The present invention relates to wear-resistant mechanical parts.

Priority: US20070896468P Applic. Date: 2007-03-22

Inventor: SKAFF HABIB [US]


Application No.: US20080233541A1  Published: 25/Sep/2008

Title: Method and Device for Enhancing the Treatment of Teeth and Gums

Applicant/Assignee: REMEDENT, INC

Application No.: 11/579916   Filing Date: 16/Mar/2005

Abstract:

An autonomous device which includes a trough, shaped for the immersion of teeth and/or gums of a dental arch, or a dental brace and one or more electrical components which provide functionality is disclosed. The device is useful in methods for whitening teeth, relieving pain, treating bacteria, treating bad breath, and healing. Inserts for use with the device are also disclosed.

Priority: WO2004EP05029 Applic. Date: 2004-05-11; WO2004EP05030 Applic. Date: 2004-05-11; WO2005EP02788 Applic. Date: 2005-03-16

Inventor: DE VREESE GUY [BE]; WILLIAMS MICHAEL [US]


Application No.: US20080233542A1  Published: 25/Sep/2008

Title: System for optimising the formation of refractory moulds for multiple metal castings in the production of fixed dental prostheses

Applicant/Assignee:

Application No.: 11/979827   Filing Date: 08/Nov/2007

Abstract:

According to the invention, the components of the system have been optimised such that they interact and complement each other and such that one cannot operate without the other in the formation of refractory moulds for multiple metal castings in the production of fixed dental prostheses. The invention also relates to a mechanical metal device for positioning increased length refractory cylinders in standard horizontal centrifuges, thereby increasing the number of fixed dental prostheses that can be cast at one time.

Priority: MX2005PA04958 Applic. Date: 2005-05-09

Inventor: MARTINEZ PROCEL JOSE LUIS [MX]


Application No.: US20080234183A1  Published: 25/Sep/2008

Title: Cell Penetrating Peptides

Applicant/Assignee:

Application No.: 10/517079   Filing Date: 18/Jun/2003

Abstract:

The present invention relates to a method for predicting or designing, detecting, and/or verifying a novel cell-penetrating peptide (CPP) and to a method for using said new CPP and/or a novel usage of a known CPP for an improved cellular uptake of a cellular effector, coupled to said CPP. Furthermore, the present invention also relates to a method for predicting or designing, detecting and/or verifying a novel cell-penetrating peptide (CPP) that mimics cellular effector activity and/or inhibits cellular effector activity. The present invention additionally relates to the use of said CPP for treating and/or preventing a medical condition and to the use of said CPP for the manufacture of a pharmaceutical composition for treating a medical condition.

Priority: SE20020001863 Applic. Date: 2002-06-18; US20020391788P Applic. Date: 2002-06-25; WO2003IB03163 Applic. Date: 2003-06-18

Inventor: HALLBRINK MATTIAS [SE]; POOGA MARGUS [EE]; METSIS MADIS [SE]; KOGERMAN PRIIT [EE]; VALKNA ANDREAS [EE]; MEIKAS ANNE [EE]; LINDGREN MARIA [SE]; GRASLUND ASTRID [SE]; ERIKSSON GORAN [SE]; OSTENSSON CLAES GORAN [SE]; BUDIHNA METKA [SI]; ZORKO MATJAZ [SI]; ELMQUIST ANNA [SE]; SOOMETS URSEL [EE]; LUNDBERG PONTUS [SE]; JARVER PETER [SE]; SAAR KULLIKI [SE]; EL-ANDALOUSSI SAMIR [SE]; KILK KALLE [SE]; LANGEL ULO [SE]


Application No.: US20080234258A1  Published: 25/Sep/2008

Title: Dihydroxyanthraquinones and Their Use

Applicant/Assignee:

Application No.: 11/997660   Filing Date: 10/Aug/2006

Abstract:

A compound of formula (1) wherein X is H or -OCR1 and Y is H or -OCR2, provided that X and Y are not both H

and R is CH2OR9, CONR11R12, CN, tetrazole or COOR17

or a salt thereof, has therapeutic utility.

Priority: GB20050016469 Applic. Date: 2005-08-10; WO2006GB02999 Applic. Date: 2006-08-10

Inventor: BAXTER ANDREW DOUGLAS [GB]; WALMSLEY ANDREA [GB]


Application No.: US20080234259A1  Published: 25/Sep/2008

Title: Novel Cannabinoid Receptor Ligands, Pharmaceutical Compositions Containing Them, and Process For Their Preparation

Applicant/Assignee: GLENMARK PHARMACEUTICALS S.A

Application No.: 11/914919   Filing Date: 01/Jun/2006

Abstract:

The present invention relates to novel cannabinoid receptor modulators, in particular cannabinoid 1 (CB1) or cannabinoid 2 (CB2) receptor modulators, and uses thereof for treating diseases, conditions and/or disorders modulated by a cannabinoid receptor (such as pain, neurodegenative disorders, eating disorders, weight loss or control, and obesity).

Priority: IN2005MU00659 Applic. Date: 2005-06-02; IN2005MU01370 Applic. Date: 2005-10-31; IN2006MU00344 Applic. Date: 2006-03-09; IN2006MI00689 Applic. Date: 2006-05-03; US20050696433P Applic. Date: 2005-07-01; US20060744071P Applic. Date: 2006-03-31; WO2006IB01437 Applic. Date: 2006-06-01

Inventor: MUTHUPPALANIAPPAN MEYYAPPAN [IN]; BALASUBRAMANIAN GOPALAN [IN]; GULLAPALLI SRINIVAS [IN]; JOSHI NEELIMA KHAIRATKAR [IN]; NARAYANAN SHRIDHAR [IN]


Application No.: US20080234315A1  Published: 25/Sep/2008

Title: M3 Muscarinic Acetylcholine Receptor Antagonists

Applicant/Assignee:

Application No.: 11/997451   Filing Date: 02/Aug/2006

Abstract:

The present invention is directed to novel Muscarinic Acetylcholine receptor antagonists of Formula (I), pharmaceutical compositions and methods of using them. Compounds of Formula (I) are, inter alia, wherein: R1 and R2 are, independently, selected from the group consisting of 3-thienyl, pyridyl, benzyl, pyrimidyl, thiazolyl, isothiazolyl and C3-7cycloalkyl.

Priority: US20050704578P Applic. Date: 2005-08-02; WO2006US30218 Applic. Date: 2006-08-02

Inventor: BUSCH-PETERSEN JAKOB [US]; LAINE DRAMANE IBRAHIM [US]; PALOVICH MICHAEL R [US]; DAVIS RODERICK S [US]; FU WEI [US]; XIE HAIBO [US]


Application No.: US20080234404A1  Published: 25/Sep/2008

Title: Dental Root Canal Filling Material

Applicant/Assignee: DENTSPLY DETREY GMBH

Application No.: 10/596742   Filing Date: 17/Dec/2004

Abstract:

A dental root canal sealing composition curable in the absence of a polymerisation initiator, which comprises (i) an amino terminated prepolymer having a viscosity at 23 DEG C. of less than 100 Pas. (ii) a compound capable of undergoing polyaddition with the aminoterminated prepolymer (i)

(iii) 40 to 85 wt.-% of a filler for providing a minimum radioopacity of at least 3 mm/mm Al.

Priority: EP20030029825 Applic. Date: 2003-12-23; WO2004EP14430 Applic. Date: 2004-12-17

Inventor: KLEE JOACHIM E [DE]


Application No.: US20080234786A1  Published: 25/Sep/2008

Title: Prevention and treatment of skin and nail infections using germicidal light

Applicant/Assignee:

Application No.: 11/980703   Filing Date: 31/Oct/2007

Abstract:

A method of prevention and treatment of microbial infections that occur on, or just below, the skin and nails of a person consisting of electromagnetic radiation to inactivate the microbes thus rendering them harmless. The treatment consists of irradiating an area of the skin and nails for a period of time long enough to inactivate the organisms. Some additional features which are not integral to the treatment but increase the safety of the treatment include shielding of non-infected areas from irradiation and a cover to prevent damage to sight which may result from viewing the electromagnetic radiation.

Priority: US2005-154707 Applic. Date: 2005-06-17; US2002-215834 Applic. Date: 2002-08-09; US20020355088P Applic. Date: 2002-02-11

Inventor: CUMBIE WILLIAM E [US]


Application No.: US20080237907A1  Published: 02/Oct/2008

Title: Process for the preparation of a polymerizable dental composition

Applicant/Assignee:

Application No.: 12/156794   Filing Date: 04/Jun/2008

Abstract:

A process for the preparation of a polymerizable dental composition comprising the steps of (a) preparing a liquid mixture comprising (i) 1 to 99% w/w of a hybrid monomer component containing at least one hybrid monomer compound having one hydrolysable siloxane group and at least one polymerizable organic moiety, and (ii) 99 to 1% w/w of a monomer component polymerizable with the polymerizable organic moiety of the hybrid monomer compounds

and (b) adding at least a stoichiometrically sufficient amount of water to the mixture to hydrolyse the hydrolysable siloxane group of the hybrid monomer compound and to form spherical polymerizable nanoparticles having an average particle size of from 1 to 100 nm dispersed in the monomer component, whereby the nanoparticles have a structure with Si-O-Si bonds and peripherally exposed polymerizable organic moieties.

Priority: US2003-617503 Applic. Date: 2003-07-11

Inventor: KLEE JOACHIM E [DE]; WALZ UWE [DE]; FACHER ANDREAS [DE]; WEBER CHRISTOPH [DE]; MULHAUPT ROLF [DE]; FREY HOLGER [DE]; MUH EKKEHARD [DE]


Application No.: US20080240978A1  Published: 02/Oct/2008

Title: Method and apparatus for two-step sterilization

Applicant/Assignee:

Application No.: 11/979751   Filing Date: 08/Nov/2007

Abstract:

The present invention relates to the field of sterilization of items that are sensitive to e.g. temperature, pH, positive or negative pressure, radiation or oxidation. More particularly, the invention concerns a method, the use of this method and an apparatus for sterilization or disinfection, comprising the steps of contacting one or more item or part of an item with (a) a water-based fluid containing at least one enzyme, and (b) a substantially water-free environment with a gas having oxidative properties, where said step (a) precedes said step (b). According to the invention, items can be sterilized that are otherwise impaired by conventional sterilization procedures, such as laboratory items, medical items, dental items, military items, biological items, and food processing-related items.

Priority: DK20060001453 Applic. Date: 2006-11-08; US20060857486P Applic. Date: 2006-11-08

Inventor: SORENSEN JAN [DK]; SIMONY CARL F [DK]; HANSEN BO [DK]


Application No.: US20080241080A1  Published: 02/Oct/2008

Title: COMPOSITION FOR TREATING XEROSTOMIA OR DRY MOUTH

Applicant/Assignee: BIOCOSMETICS, S.L

Application No.: 12/036005   Filing Date: 22/Feb/2008

Abstract:

The present invention provides a composition comprising olive oil, trimethylglycine and xylitol for treating xerostomia and disorders associated thereto, with very good results in increasing the unstimulated salivary flow, in alleviating the symptoms of xerostomia, including the pain associated to xerostomia, as well as improving the quality of life of affected persons. The composition of the invention has also been proved to protect dentin against demineralization in acid conditions.

Priority: ES20070000464 Applic. Date: 2007-02-22; US20070891160P Applic. Date: 2007-02-22

Inventor: RODRIGUEZ-VILABOA DEBORA [ES]


Application No.: US20080241122A1  Published: 02/Oct/2008

Title: Dental Composition Comprising Enzyme

Applicant/Assignee:

Application No.: 12/063873   Filing Date: 16/Aug/2006

Abstract:

The present invention relates to a dental composition comprising an enzyme having an enzyme activity at acidic pH values, a buffer providing an acidic pH value and one or more preservative agents, wherein at least one preservative agent is active at acidic pH.

Priority: EP20050017845 Applic. Date: 2005-08-17; WO2006US31904 Applic. Date: 2006-08-16

Inventor: KAPPLER OLIVER [DE]; HAEBERLEIN INGO R [DE]


Application No.: US20080241211A1  Published: 02/Oct/2008

Title: DEVICE WHICH ENHANCES THE BIOLOGICAL ACTIVITY OF LOCALLY APPLIED GROWTH FACTORS WITH PARTICULAR EMPHASIS ON THOSE USED FOR BONE REPAIR

Applicant/Assignee: UNIVERSITY OF SOUTHERN CALIFORNIA

Application No.: 12/057236   Filing Date: 27/Mar/2008

Abstract:

This invention provides a novel medical appliance for repairing, regenerating, maintaining, and/or augmenting a bone. The medical appliance generally includes an osteoinductive agent, an osteoinductive enhancer, and a carrier matrix. Also disclosed are methods, compositions, kits, and bone matrix formulations for regenerating, maintaining, and/or augmenting a bone. Exemplary preferred osteoinductive agents include growth factors such as BMP and TGF-beta. Exemplary preferred osteoinductive enhancers include phytoestrogens such as naringin.

Priority: US20070908262P Applic. Date: 2007-03-27

Inventor: HAN BO [US]; NIMNI MARCEL [US]


Application No.: US20080241551A1  Published: 02/Oct/2008

Title: Graded glass/zirconia/glass structures for damage resistant ceramic dental and orthopedic prostheses

Applicant/Assignee:

Application No.: 11/983815   Filing Date: 09/Nov/2007

Abstract:

The present invention provides a functionally graded glass/ceramic/glass sandwich system for use in damage resistant, ceramic and orthopedic prosthesis. The functionally graded glass/substrate/glass composite structure comprises an outer residual glass layer, a graded glass-ceramic layer, and a dense interior ceramic. The functionally graded glass/substrate/glass composite structure may further comprise a veneer on an exterior surface. The present invention also provides a method for preparing a functionally graded glass/ceramic/glass sandwich system. A powdered glass-ceramic composition is applied to the accessible surfaces of a presintered zirconia substrate to thereby substantially cover the substrate surfaces. The glass of the composition has a CTE similar to that of the substrate material. The glass-ceramic composition is infiltrated into and densifies the substrate by heating the assembly to at least the sintering temperature of the substrate.

Priority: US20060858234P Applic. Date: 2006-11-09

Inventor: ZHANG YU [US]; KIM JAE-WON [US]


Application No.: US20080241788A1  Published: 02/Oct/2008

Title: METHOD FOR THE MANUFACTURE OF DENTAL PROSTHESES

Applicant/Assignee: DEGUDENT GMBH

Application No.: 12/045146   Filing Date: 10/Mar/2008

Abstract:

The invention relates to the use of a cobalt-chromium alloy in the manufacture of a dental prosthesis. The alloy contains: 43-68% by weight cobalt, 12-30% by weight chromium, 8-25% by weight tungsten, 0-13% by weight iron, 0-30% by weight manganese, 0-10% by weight molybdenum, 0-5% by weight of at least one of the elements aluminum, tantalum, rhenium, titanium and less than 0.1% by weight carbon. A dental prosthesis with favorable workability and a low corrosion rate is obtained by manufacturing the dental prosthesis by means of a laser melting and/or sintering process.

Priority: EP20070104431 Applic. Date: 2007-03-19

Inventor: BAUER JOCHEN [DE]; KLAUS ANGELA [DE]; STEINKE RUDI [DE]; WEISENSEL LARS [DE]


Application No.: US20080241800A1  Published: 02/Oct/2008

Title: Dental Composition For Detection of Carious Tissue, Detection Method

Applicant/Assignee:

Application No.: 11/914990   Filing Date: 24/May/2006

Abstract:

The present invention relates to a dental composition comprising an aqueous solution of 1) at least one acidic compound, 2) at least one salt of said acidic compound, 3) at least one indicator that generates a detectable signal when said solution reaches a particular pH value that is less than 5.5 wherein 1) and 2) are selected such that the aqueous solution has a pH of less than that particular pH value where the indicator generates the signal. It further relates to a method for detection of carious tissue on the surface of a tooth, comprising the steps of 1) providing the above mentioned dental composition, 2) applying said composition to the surface of said tooth, and 3) measuring the amount of time required for the composition to change color. It further relates to the use of said dental composition to manufacture a remedy for detection of carious tissue.

Priority: EP20050011336 Applic. Date: 2005-05-25; WO2006EP05004 Applic. Date: 2006-05-24

Inventor: GUGGENBERGER RAINER [DE]; LUCHTERHANDT THOMAS [DE]; HAEBERLEIN INGO R [DE]; HANSEN MIRIAM [DE]


Application No.: US20080242582A1  Published: 02/Oct/2008

Title: COMPOSITIONS CONTAINING BENEFIT AGENT COMPOSITES PRE-EMULSIFIED USING COLLOIDAL CATIONIC PARTICLES

Applicant/Assignee: AMCOL INTERNATIONAL CORPORATION

Application No.: 12/028685   Filing Date: 08/Feb/2008

Abstract:

A cleansing or a surface-conditioning composition comprising a mixture of (i) and (ii) in water: i) a surfactant selected from the group consisting of anionic, non-ionic, zwitterionic, cationic, and mixtures thereof, and ii) a hydrophobic benefit agent in a particulate form having a mean particle size in the range of 1-1,000 micron, and a specific gravity of >=1, not encapsulated within a film or a capsule-like enclosure, the particulate hydrophobic benefit agent comprising: a) a physically-modified form of the hydrophobic benefit agent

and b) a deposition-aid material bonded to the surface of the physically-modified benefit agent material, wherein the bonding between the two said materials is achieved prior to addition to i), wherein said deposition-aid material is not a surfactant having a weight average molecular weight of less than 5,000 Dalton.

Priority: US2006-331248 Applic. Date: 2006-01-12; US20070900250P Applic. Date: 2007-02-08

Inventor: SENGUPTA ASHOKE K [US]; LIN ILONA [US]; ONGE JASON ST [US]


Application No.: US20080242694A1  Published: 02/Oct/2008

Title: Amino-substituted heterocycles, compositions thereof, and methods of treatment therewith

Applicant/Assignee:

Application No.: 11/901598   Filing Date: 17/Sep/2007

Abstract:

Provided herein are Heterocyclic Compounds having the following structure: wherein R<1>, R<2>, X, Y and Z are as defined herein, compositions comprising an effective amount of a Heterocyclic Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heterocyclic Compound to a patient in need thereof.

Priority: US20060845558P Applic. Date: 2006-09-18

Inventor: D SIDOCKY NEIL R [US]; HARRIS ROY L [US]; HEGDE SAYEE G [US]; HILGRAF ROBERT [US]; MCCARRICK MARGARET A [US]; MCKIE JEFFREY A [US]; MORTENSEN DEBORAH S [US]; NADOLNY LISA [US]; PERIN-NINKOVIC SOPHIE M [US]; SAPIENZA JOHN J [US]; WRIGHT JONATHAN L [US]


Application No.: US20080242760A1  Published: 02/Oct/2008

Title: Poly (Dialkylsiloxane) For Improving Surface of Dental Fillings

Applicant/Assignee: STICHTING GLASS FOR HEALTH

Application No.: 10/599095   Filing Date: 21/Mar/2005

Abstract:

The present invention relates to a use of a poly(dialkylsiloxane) having terminal hydroxyl groups, wherein the alkyl groups contain 1 to 4 carbon atoms, for improving the strength and the surface of dental fillings that are based on glass ionomer cement compositions.

Priority: EP20040075907 Applic. Date: 2004-03-19; WO2005NL00212 Applic. Date: 2005-03-21

Inventor: VAN DEN BOSCH WILLEM FREDERIK [NL]; VAN DUINEN RAIMOND NICOLAAS BRUNO [NL]


Application No.: US20080242761A1  Published: 02/Oct/2008

Title: SELF ETCH ALL PURPOSE DENTAL COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF

Applicant/Assignee:

Application No.: 11/866082   Filing Date: 02/Oct/2007

Abstract:

A one-part self-etching and bonding dental resin composition comprising in combination about 10 to about 30 weight percent of a polymerizable (meth)acrylate carboxylic acid/anhydride, based on the total weight of the polymerizable components in the composition

a copolymerizable multi-functional (meth)acrylate resin

a copolymerizable diluent monomer

and a curing system. The composition has the advantage of not requiring a separate etching and bonding step.

Priority: US2007-677607 Applic. Date: 2007-02-22; US2006-360314 Applic. Date: 2006-02-23

Inventor: JIA WEITAO [US]; JIN SHUHUA [US]


Application No.: US20080242834A1  Published: 02/Oct/2008

Title: Methods of Predicting Hyp-Glycosylation Sites For Proteins Expressed and Secreted in Plant Cells, and Related Methods and Products

Applicant/Assignee: OHIO UNIVERSITY

Application No.: 11/995063   Filing Date: 10/Jul/2006

Abstract:

Proteins with Hyp-glycosylation are more likely to be secreted in plant cells at high levels than those without. Methods are disclosed for the prediction of Pro-hydroxylation and Hyp-glycosylationsites in proteins. Such methods can be used to identify (1) proteins which, without modification, are predisposed to develop Hyp-glycosylation, if expressed in plant cells, and (2) modifications (especially substitution mutations) which increase the propensity of a protein to develop Hyp-glycosylation, with a view to high level or increased secretion. It is also possible to determine empirically whether a particular protein will undergo Hyp-glycosylation suitable for the desired level of secretion in plant cells. Both modified proteins, and methods for the expression and secretion of predisposed and modified proteins, are claimed.

Priority: US20050697337P Applic. Date: 2005-07-08; WO2006US26594 Applic. Date: 2006-07-10

Inventor: KIELISZEWSKI MARCIA J [US]; XU JIANFENG [US]


Application No.: US20080245268A1  Published: 09/Oct/2008

Title: DENTAL COMPOSITES AND PLACEMENT TECHNIQUES FOR DIRECT RESTORATIONS

Applicant/Assignee: IVOCLAR VIVADENT, INC IVOCLAR VIVADENT INC

Application No.: 12/138202   Filing Date: 12/Jun/2008

Abstract:

Colorless dental compositions for restoring the enamel layer of a tooth are disclosed. The colorless enamel compositions are combined with pigmented dentin compositions to provide a true color match and natural esthetics. Methods that utilize the compositions in placement/build-up techniques in direct restorations are also disclosed.

Priority: US2004-824799 Applic. Date: 2004-04-15; US20030531886P Applic. Date: 2003-12-22

Inventor: CULP TERRY LEE [US]


Application No.: US20080245923A1  Published: 09/Oct/2008

Title: Machine and Method for the Production of Rolls of Weblike Material Together with a Winding Core and Roll Thus Obtained

Applicant/Assignee: FABIO PERINI S.P.A

Application No.: 11/919674   Filing Date: 27/Apr/2006

Abstract:

Described herein is a rewinding machine for the production of rolls (L) of weblike material around winding cores, including a path for the weblike material (N) and a winding area, in which said weblike material is wound in rolls. The machine moreover comprises a feeder for feeding a sheetlike material (F) towards the path of the weblike material, and forming members ( 13, 15 ) for rolling a length of said sheetlike material and forming therewith a winding core around which a roll of weblike material is formed.

Priority: IT2005FI00088 Applic. Date: 2005-05-02; WO2006IT00287 Applic. Date: 2006-04-27

Inventor: MADDALENI ROMANO [IT]; BENVENUTI ANGELO [IT]; MAZZACCHERINI GRAZIANO [IT]


Application No.: US20080247681A1  Published: 09/Oct/2008

Title: POUCH WITH SPOUT

Applicant/Assignee:

Application No.: 11/697473   Filing Date: 06/Apr/2007

Abstract:

A reclosable container with a slider arranged to open and close interlockable profiles on the mouth of the container. The profiles are fixed together at one end but are separable at the other end to allow a gusset to fold outwardly to form a pour spout.

Priority:

Inventor: STOLMEIER ROBERT C [US]


Application No.: US20080247966A1  Published: 09/Oct/2008

Title: Compositions and Methods to Counteract Oral Malodour

Applicant/Assignee: GIVAUDAN SA

Application No.: 12/064499   Filing Date: 24/Aug/2006

Abstract:

The invention relates to hedonistically pleasing oral malodour counteracting compositions including flavour compositions and oral care products, methods to form such compositions and methods to counteract oral malodour. The compositions comprises 4 or more of oral malodour counteracting actives in a total concentration of at least 20% (w/w) based on the total concentration of flavour ingredients, and an individual concentration of 1% or more per oral malodour counteractant, based on total flavour ingredients. The maximum concentration of any individual oral malodour counteracting active based on the total of oral malodour counteracting actives is 70%. The identified oral malodour counteracting actives are various flavour compounds and natural ingredients.

Priority: GB20050017573 Applic. Date: 2005-08-30; WO2006CH00459 Applic. Date: 2006-08-24

Inventor: NATSCH ANDREAS [CH]; MORAES EDUARDO [CH]


Application No.: US20080248086A1  Published: 09/Oct/2008

Title: CURABLE THERAPEUTIC IMPLANT COMPOSITION

Applicant/Assignee: CINVENTION AG

Application No.: 12/062689   Filing Date: 04/Apr/2008

Abstract:

The exemplary embodiments of the present invention relates to a curable therapeutic implant composition for use in the filling of a cavity in a living organism, comprising particles of a metallic material, and a curable matrix-forming, non-particulate material, wherein at least one of the metallic material or the matrix-forming material is at least partially degradable in-vivo. Furthermore, the exemplary embodiments of the present invention relate to methods of filling a cavity in a living organism with the use of the curable implant composition.

Priority: US20070910455P Applic. Date: 2007-04-05

Inventor: ASGARI SOHEIL [DE]


Application No.: US20080248090A1  Published: 09/Oct/2008

Title: GRADUATED CONCENTRATION SODIUM CHLORIDE PATCHES FOR THE TREATMENT OF DENTAL CONDITIONS

Applicant/Assignee:

Application No.: 12/137731   Filing Date: 12/Jun/2008

Abstract:

A plurality of patches are prepared, containing a therapeutic agent, particularly NaCl, another salt, or another type of agent, for being held in contact with a portion of the oral cavity in order to treat a dental condition. The patches have respective concentrations of NaCl such that the concentrations cover a range from substantially hypotonic to substantially hypertonic. In particular, the plurality of patches may have a corresponding plurality of respective concentrations between about 0.22% and about 25% (weight/volume).

Priority: US2005-197239 Applic. Date: 2005-08-03; US20050678892P Applic. Date: 2005-05-09

Inventor: SUNNEN GERARD V [US]


Application No.: US20080248105A1  Published: 09/Oct/2008

Title: POLYMORPHIC FORMS OF 6-11 BICYCLIC KETOLIDE DERIVATIVES

Applicant/Assignee:

Application No.: 12/105482   Filing Date: 18/Apr/2008

Abstract:

The present invention includes EP-13420 polymorphic crystalline forms: Form I, Form II, Form Ia, and monohydrate and amorphous EP-13420 which posses distinct physical properties. In another embodiment of the present invention, there are provided methods of producing the various polymorphic forms in pure form or in combination with one another. The present invention also provides pharmaceutical compositions and formulations comprising the polymorphic and amorphous forms and methods of treating bacterial infections by administering the pharmaceutical compositions to a subject in need of such treatment.

Priority: US2005-057476 Applic. Date: 2005-02-14; US20040546433P Applic. Date: 2004-02-20; US20040615803P Applic. Date: 2004-10-04

Inventor: TANG DATONG [US]; XU GUOYOU [US]; GAI YONGHUA [US]; WANG ZHE [US]; OR YAT SUN [US]; LI HUI-YIN [US]


Application No.: US20080248124A1  Published: 09/Oct/2008

Title: Process for producing pharmaceutical composition

Applicant/Assignee: SUNSTAR KABUSHIKI KAISHA

Application No.: 11/730746   Filing Date: 03/Apr/2007

Abstract:

The present invention relates to a process for producing a pharmaceutical composition which can stably contain an active ingredient unstable against water and can sustained-release such the active ingredient for a long period of time by remaining at an administrated portion as well as a pharmaceutical composition produced by the same. Specifically, the present invention relates to a process for producing a pharmaceutical composition, comprising steps of: mixing and heating a first phase, prepared by mixing a polyhydric alcohol and a salt, and a second phase containing a water-soluble polymer under a reduced pressure, before evaporating substantially all water in the first phase by mixing and heating a mixture of first and second phases under a reduced pressure or after evaporating substantially all water in the first phase by mixing and heating the first phase under a reduced pressure

and adding a third phase containing an active ingredient unstable against water and mixing them to obtain the pharmaceutical composition, as well as a pharmaceutical composition produced the same.

Priority:

Inventor: EGUCHI TORU [JP]; HASEGAWA KENJI [JP]


Application No.: US20080248438A1  Published: 09/Oct/2008

Title: ORTHODONTIC APPLIANCES AND MATERIALS FOR MAKING SAME

Applicant/Assignee:

Application No.: 11/947172   Filing Date: 29/Nov/2007

Abstract:

The polymeric shell of a removable dental positioning appliance is formed from transparent polymeric materials having a tensile strength at yield of greater than 6,000 pounds per square inch (psi), an elongation at yield of greater than 4%, an elongation at break of greater than 80%, a tensile modulus greater than 200,000 psi, a flexural modulus greater than 200,000 psi, stress relaxation over time of not more than 50%, and a transmissivity of light between 400 nm and 800 nm greater than 75%.

Priority: US2004-963147 Applic. Date: 2004-10-12

Inventor: DESIMONE JOSEPH M [US]; TRICCA ROBERT E [US]


Application No.: US20080248445A1  Published: 09/Oct/2008

Title: Dental abrasive strip

Applicant/Assignee:

Application No.: 11/732815   Filing Date: 05/Apr/2007

Abstract:

A abrasive dental filing strip coated with some superfine abrasive material, especially but not limited to diamond dust like particles, or alternatively a sharp cutting system along the lateral surface, and having cutting edge like serrated or saw tooth along the longitudinal edge or edges.

Priority:

Inventor: KIM DANIEL SUNGYUL [US]


Application No.: US20080248447A1  Published: 09/Oct/2008

Title: Interproximal Tooth Defects Detection

Applicant/Assignee: DENTSPLY CANADA LTD

Application No.: 12/065093   Filing Date: 29/Aug/2006

Abstract:

There is provided a method for detecting interproximal tooth defects such as caries by injecting light at one or more wavelengths into a tooth and detecting reflected/diffracted light or emitted fluorescence. The detected light intensity is characteristic of a healthy or diseased tooth in the interproximal area.

Priority: CA20052517252 Applic. Date: 2005-08-29; WO2006CA01422 Applic. Date: 2006-08-29

Inventor: KARAZIVAN NAIM [CA]


Application No.: US20080248714A1  Published: 09/Oct/2008

Title: Fan Attachment Arrangement

Applicant/Assignee: WHETSTONE MANAGEMENT LLC

Application No.: 12/098683   Filing Date: 07/Apr/2008

Abstract:

An attachment arrangement for use in connection with an existing ceiling fan having a plurality of rotatable fan blades. The arrangement includes a connecting arrangement for attaching an object to at least a portion of at least one of the fan blades, such that, as the fan blade rotates, the object rotates via the connecting arrangement.

Priority: US20070921937P Applic. Date: 2007-04-05

Inventor: ZACHARIAS ANNE [US]; FRAZZINI ROBERT [US]


Application No.: US20080249030A1  Published: 09/Oct/2008

Title: Age Inhibitors

Applicant/Assignee:

Application No.: 11/909761   Filing Date: 30/Mar/2006

Abstract:

The invention relates to a compound having general formula I, wherein: X represents CH2, C-O, C-S or CHOH, X represents CH2, C-O, C-S or CHOH, R1 represents an amino acid which is optionally substituted by one or more halogen atoms, preferably fluorine, or by one or more CF3 groups and n=0.1 or 2, or X represents CH2, C-O, C-S, CHOH, R1 represents a peptide containing two amino acids, each amino acid being optionally substituted by one or more halogen atoms, preferably fluorine, or by one or more CF3 groups and n=0 or 1, or XR1 represent PO3H or SO3H and n=0.1 or 2

R2 represents H, XR1, an alkyl group at C1-C6, an aralkyl group at C1-C6 or an aryl group, whereby the alkyl, aralkyl and aryl groups can be substituted by an amine NH2, a carboxylic group COOH, one or more halogen atoms, preferably fluorine, or one or more CF3 groups

or the pharmaceutically-acceptable addition salts, isomers, enantiomers and diastereoisomers of said compound, mixtures thereof, and pharmaceutical or cosmetic compositions comprising same and the use thereof as an AGE-inhibitor drug that traps reactive carbonyl compounds.

Priority: FR20050003176 Applic. Date: 2005-03-31; WO2006EP61191 Applic. Date: 2006-03-30

Inventor: POTIER PIERRE [FR]; ZELVEYAN MARIE-CLAUDE DENISE MICHELE [FR]; MAGNAN CATHARINE MARIE GERMAIN [FR]


Application No.: US20080249127A1  Published: 09/Oct/2008

Title: Muscarinic Acetylcholine Receptor Antagonists

Applicant/Assignee:

Application No.: 10/585830   Filing Date: 13/Jan/2005

Abstract:

Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.

Priority: US20040536092P Applic. Date: 2004-01-13; WO2005US01333 Applic. Date: 2005-01-13

Inventor: LAINE DRAMANE I [US]; PALOVICH MICHAEL R [US]; PRESTON ALEXANDER G [GB]; COOPER ANTHONY WILLIAM JAMES [GB]


Application No.: US20080249616A1  Published: 09/Oct/2008

Title: Reinforced Porous Coating

Applicant/Assignee:

Application No.: 12/066114   Filing Date: 15/Sep/2006

Abstract:

The present invention relates to a process for manufacturing a porous coating with structures in the micro or nano-size domain characterized by the following steps: -providing a support having a surface, -depositing on said surface one mono-layer of temporary particles, -depositing a coating on said temporary particles in such a way that the thickness of said coating is less than the particle diameter, -eliminating said temporary particles and thereby obtaining a porous coating, the pores of said coating corresponding to the spaces previously occupied by the temporary particles and at least a part of the pores communicating with the external environment, -applying a coating fixation step, characterized by the fact that said temporary particles are deposited on said surface in such a way that, after particle deposition, more than 50% of the temporary particles are in contact with a maximum of two adjacent particles and otherwise are separated by an empty space. The invention also concerns a coating and an object which can be obtained with this process.

Priority: EP20050108573 Applic. Date: 2005-09-16; WO2006IB53327 Applic. Date: 2006-09-15

Inventor: HOFMANN HEINRICH [CH]; NEFTEL FREDERIC [CH]; PIVETEAU LAURENT-DOMINIQUE [CH]


Application No.: US20080249635A1  Published: 09/Oct/2008

Title: GASTRIC FILLER DEVICES FOR OBESITY THERAPY

Applicant/Assignee:

Application No.: 12/052293   Filing Date: 20/Mar/2008

Abstract:

An obesity treatment device comprises a filament filler material movable between a substantially straight insertion/removal configuration and an operative configuration in which the filament extends along a predetermined curve to occupy a selected volume within the stomach and a retrieval device connected to a proximal end of the filler material facilitating grasping and withdrawal of the filler material. A method of treating obesity, comprises inserting to a desired position within the GI tract a filament filler in a substantially straight configuration and moving the filler into an operative configuration in which the filler curves along a predetermined path to define a desired volume in combination with, after a predetermined treatment period has elapsed, collapsing the filler into the substantially straight configuration for trans-oral removal.

Priority: US20070910356P Applic. Date: 2007-04-05

Inventor: WEITZNER BARRY [US]; MORECI STEPHEN [US]


Application No.: US20080249637A1  Published: 09/Oct/2008

Title: PARTIALLY BIODEGRADABLE THERAPEUTIC IMPLANT FOR BONE AND CARTILAGE REPAIR

Applicant/Assignee: CINVENTION AG

Application No.: 12/098282   Filing Date: 04/Apr/2008

Abstract:

Exemplary embodiment of the present invention is directed to an at least partially biodegradable implant suitable for implantation into a subject for repairing a bone or cartilage defect, comprising a three-dimensional open-celled framework structure made of a non-particulate first material, the framework structure being embedded in a second, non-particulate material different from said first material, or the open-celled framework structure being substantially completely filled with said second, non-particulate material, wherein at least one of the first material or the second material is at least partially degradable in-vivo. Furthermore, the present invention is directed to a method for repairing a bone or cartilage defect in a living organism, comprising implanting an implant according to the exemplary embodiment of the present invention into the defective bone or cartilage, or replacing the defective bone or cartilage at least partially.

Priority: US20070910456P Applic. Date: 2007-04-05

Inventor: ASGARI SOHEIL [DE]


Application No.: US20080249638A1  Published: 09/Oct/2008

Title: BIODEGRADABLE THERAPEUTIC IMPLANT FOR BONE OR CARTILAGE REPAIR

Applicant/Assignee: CINVENTION AG

Application No.: 12/098722   Filing Date: 07/Apr/2008

Abstract:

The exemplary embodiments of the present invention relate to an at least partially biodegradable implant suitable for implantation into a subject for repairing a bone or cartilage defect, comprising a matrix forming an open-celled structure having a plurality of interconnected spaces, whereas the channels of the matrix are substantially completely filled with metallic material particles, and wherein at least one of the metallic material or the matrix material is at least partially degradable in-vivo. Furthermore, the present invention relates to a method for repairing a bone or cartilage defect in a living organism, comprising implanting an implant according to the exemplary embodiments of the present invention into the defective bone or cartilage, or replacing the defective bone or cartilage at least partially.

Priority: US20070910454P Applic. Date: 2007-04-05

Inventor: ASGARI SOHEIL [DE]


Application No.: US20080251098A1  Published: 16/Oct/2008

Title: TOOTHPICK WITH BRISTLES

Applicant/Assignee:

Application No.: 11/735458   Filing Date: 14/Apr/2007

Abstract:

A toothpick with bristles, the toothpick has a rod being laid out on its surface bristles coated each with a coating layer, the material of the coating layer can be mouth rinsing water, cleaning liquid, toothpaste powder or cooling material. When in clearing filth between teeth, coating layers can give a user a comfortable feeling. And a packing unit is provided for loading therein a plurality of toothpicks with bristles

the packing unit has a receiving space for storing material which can form the coating layers for the bristles of the toothpicks by dipping.

Priority:

Inventor: CHEN CHIN-YEN [TW]


Application No.: US20080251597A1  Published: 16/Oct/2008

Title: Therapeutic training straw

Applicant/Assignee:

Application No.: 12/073421   Filing Date: 05/Mar/2008

Abstract:

A drinking straw for controlling the intake of beverages, comprising an elongated hollow member having at least two open ends, at least one end being a suction end adapted for application of a suction force, and at least one end being a liquid end adapted for immersion in a liquid beverage

at least one compartment associated with each at least one suction end and located between the associated at least one suction end and the at least one liquid end and having openings for communicating the liquid beverage therethrough

and at least one insoluble object within the at least one compartment having an outer circumference smaller than an inner circumference of the at least one compartment

wherein the compartment openings and the object are dimensioned to prevent escape of the object from the compartment

and wherein the at least one object seals at least one compartment opening subsequent to the application of the suction force to prevent the movement of the liquid beverage past the opening.

Priority: US2005-202027 Applic. Date: 2005-08-12

Inventor: PEARSON CALVIN M [US]


Application No.: US20080251954A1  Published: 16/Oct/2008

Title: Strip diffuser

Applicant/Assignee:

Application No.: 11/808554   Filing Date: 11/Jun/2007

Abstract:

Membrane strip diffusers are disclosed, useful for example in aerating wastewater in activated sludge plants. These diffusers have membranes, diffuser bodies comprising gas conduits and, in addition to the conduits, integral membrane supports elongated in the same general direction. Such conduits are for example co-extruded with the diffuser bodies. The supports are apertured to discharge gas into chambers formed beneath the membranes when they inflate, and the membranes have pores to discharge the gas. Ways to edge- and end-seal the membranes to the diffuser bodies and ways to support the diffusers are also disclosed.

Priority: US2003-639774 Applic. Date: 2003-08-13; US20020408284P Applic. Date: 2002-09-06; US20020402715P Applic. Date: 2002-08-13

Inventor: CASPER THOMAS J [US]; SCHOENENBERGER MARK A [US]; LAUBENSTEIN BRAD D [US]; REILLY JAMES A [US]; KRALL JOSEPH G [US]; TISCHLER NEIL S [US]


Application No.: US20080253522A1  Published: 16/Oct/2008

Title: Tool associated with compton scattered X-ray visualization, imaging, or information provider

Applicant/Assignee: SEARETE LLC, A LIMITED LIABILITY CORPORATION OF THE STATE OF DELAWARE

Application No.: 11/786743   Filing Date: 11/Apr/2007

Abstract:

One aspect relates to providing an at least one Compton scattered X-ray visualizing, imaging, or information providing operation relative to at least one visualizing, imaging, or information providing region within an at least some matter of an at least a portion of an individual

and providing a tool-based operation to at least the portion of the at least one visualizing, imaging, or information providing region within the at least some matter of the at least the portion of the individual based at least partially on the providing the at least one Compton scattered X-ray visualizing, imaging, or information providing operation relative to the at least the portion of the at least one visualizing, imaging, or information providing region.

Priority:

Inventor: BOYDEN EDWARD S [US]; HYDE RODERICK A [US]; ISHIKAWA MURIEL Y [US]; JUNG EDWARD K Y [US]; LEUTHARDT ERIC C [US]; LORD ROBERT W [US]; MYHRVOLD NATHAN P [US]; RIVET DENNIS J [US]; SMITH MICHAEL A [US]; TEGREENE CLARENCE T [US]; WEAVER THOMAS A [US]; WHITMER CHARLES [US]; WOOD LOWELL L [US]; WOOD VICTORIA Y H [US]


Application No.: US20080253973A1  Published: 16/Oct/2008

Title: SENSATION MODIFYING TOPICAL COMPOSITION FOAM

Applicant/Assignee: FOAMIX LTD

Application No.: 11/971197   Filing Date: 08/Jan/2008

Abstract:

This invention relates to foamable compositions that are capable of producing a sensation or sensation modifying effect upon application on a body surface. More particularly the invention relates to foamable pharmaceutical, therapeutic and cosmetic compositions, comprising an active agent, having a sensation or sensation modifying affect on a body surface, upon application. More particularly, the invention relates to foamable compositions comprising: (a) a foamable carrier

(b) at least one sensation or sensation modifying agent, selected from the group of a cooling agent

a warming agent

a relaxing or soothing agent

stimulating or refreshing agent

or mixtures thereof and (c) a propellant at a concentration of about 3% to about 45% by weight of the total composition. The foamable carrier can be an emollient emulsion foamable vehicle, a foamable gel vehicle and can also be a substantially non aqueous foamable vehicle.

Priority: IL20020152486 Applic. Date: 2002-10-25; US2005-532618 Applic. Date: 2005-12-22; US2004-911367 Applic. Date: 2004-08-04; US2004-835505 Applic. Date: 2004-04-28; US20070879213P Applic. Date: 2007-01-08; US20030492385P Applic. Date: 2003-08-04; US20030530015P Applic. Date: 2003-12-16

Inventor: TAMARKIN DOV [IL]; EINI MEIR [IL]; FRIEDMAN DORON [IL]; ZLATKIS ELLA [IL]; SCHUZ DAVID [IL]; BERMAN TAL [IL]


Application No.: US20080253975A1  Published: 16/Oct/2008

Title: COMPOSITION FOR DYEING DENTAL PLAQUE FOR EVALUATING DENTAL CARIES ACTIVITY

Applicant/Assignee: GC CORPORATION

Application No.: 11/733387   Filing Date: 10/Apr/2007

Abstract:

An objective of the present invention is to provide a composition for dyeing dental plaque for evaluation of dental caries activity that is capable of simultaneously dyeing dental plaque and evaluating dental caries activity, and which can evaluate thick dental plaque more accurately than the conventional technique. The composition for dyeing dental plaque for evaluation dental caries activity comprises: a blue pigment being dissolved in water and having a color tone not changing at pH 7 or less

a red pigment being dissolved in water at pH more than 4.5 but not dissolved in water at pH 4.5 or less, and having a color tone not changing at pH 4.5 or less

and sugar. The content of sugar is preferably 1 to 50 weight parts to the total of 1 weight part of contents of the blue pigment and the red pigment, and ratio of contents of the blue pigment and the red pigment is preferably 1:3 to 3:1.

Priority:

Inventor: WALSH LAURENCE J [AU]; OTA RYOKO [JP]; NAGAO SAYAKA [JP]; SATO TAKUYA [JP]


Application No.: US20080253976A1  Published: 16/Oct/2008

Title: Personal Care Compositions Comprising An Antimicrobial Blend of Essential Oils or Constituents Thereof

Applicant/Assignee:

Application No.: 12/062870   Filing Date: 04/Apr/2008

Abstract:

Disclosed are personal care compositions, including compositions for oral, throat and skin care comprising a blend of naturally occurring flavor or perfume ingredients or essential oils containing such ingredients, wherein the blend provides excellent antimicrobial activity and comprises at least two components, a first acyclic component selected from citral, neral, geranial, geraniol and nerol and a second cyclic-containing component selected from eucalyptol, carvacrol and eugenol. Preferably, the blend comprises 3, 4, 5 or more of the above components. Greater synergy in terms of antimicrobial efficacy may be obtained the more different components are blended together. The present compositions are effective in killing, suppressing the growth of and/or altering metabolism of microorganisms including those which cause undesirable oral cavity conditions including plaque, caries, calculus, gingivitis, periodontal disease and malodor. Optionally the blend further comprises additional antimicrobial and/or anti-inflammatory components, preferably naturally-occurring as well.

Priority: US20070923652P Applic. Date: 2007-04-16

Inventor: SCOTT DOUGLAS CRAIG [US]; SANKER LOWELL ALAN [US]; GOULBOURNE ERIC ALTMAN [US]


Application No.: US20080254079A1  Published: 16/Oct/2008

Title: NOVEL COMPOSITIONS CONTAINING LYSOZYME AND C-1/C-4 POLYSACCHARIDES AND USE THEREOF IN ORAL CARE, COSMETOLOGY AND DERMATOLOGY, CONTRACEPTION, UROLOGY AND GYNECOLOGY

Applicant/Assignee: SAINT SIMEON LDA

Application No.: 12/100091   Filing Date: 09/Apr/2008

Abstract:

A composition comprising a content of a lysozyme and a content of a C-1/C-4 polysaccharide is useful in oral care, cosmetology and dermatology, contraception, urology and gynecology. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader quickly to ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the appended issued claims. 37 CFR PRG 1.72(b).

Priority: US20070910880P Applic. Date: 2007-04-10

Inventor: FERRARI STEFANO [US]


Application No.: US20080254101A1  Published: 16/Oct/2008

Title: PILOCARPINE COMPOSITIONS AND METHODS OF USE THEREOF

Applicant/Assignee:

Application No.: 12/146391   Filing Date: 25/Jun/2008

Abstract:

The present invention provides novel compositions for the delivery of pilocarpine or a pharmaceutically acceptable salt thereof across the oral mucosa, preferably across the buccal mucosa. In particular, the buffer systems in the compositions of the present invention contain an amount of a strong base that is less than the amount of a weak base, thereby increasing the stability of compositions such as chewing gum compositions and raising the pH of saliva to a pH greater than about 7.5 to facilitate the substantially complete conversion of pilocarpine from its ionized to its un-ionized form. Methods for using the compositions of the present invention for treating conditions such as dry mouth are also provided.

Priority: US2005-195567 Applic. Date: 2005-08-01; US20040598625P Applic. Date: 2004-08-03

Inventor: SINGH NIKHILESH N [US]


Application No.: US20080254130A1  Published: 16/Oct/2008

Title: Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction

Applicant/Assignee: BIODERM RESEARCH

Application No.: 12/139462   Filing Date: 14/Jun/2008

Abstract:

The present invention relates to a topical method of treatment for dysfunction of certain dermal enzymes, and the treatment of skin condition or disorder caused by said dysfunction. The said method of treatment consists of (i) an extra-cellular, matrix metalloprotease regulating agent, and (ii) an intra-cellular ubiquitin-proteasome regulating agent, and (iii) an epidermal melanocyte-regulating agent

and, wherein, said extra-cellular agent, said intracellular agent, and said epidermal agent can, surprisingly and unexpectedly, be a single multi-function compound having chemical formula (I). Additionally, the method of the present invention provides treatment of skin condition or disorder caused by dysfunction of said dermal enzymes

wherein said skin disorder is skin aging, skin wrinkles, dark skin, age spots, acne, skin inflammation, loss of cellular antioxidants, loss of collagen, loss of skin pliability, loss of skin suppleness, oily skin, or a combination thereof:

Priority: US2003-604999 Applic. Date: 2003-08-29

Inventor: GUPTA SHYAM K [US]


Application No.: US20080254400A1  Published: 16/Oct/2008

Title: Method and Tool For Oral Substrate Measurement In Animals

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/090108   Filing Date: 13/Oct/2006

Abstract:

A gingival contour probe comprising a shaft portion and an elongated tip portion attached at a proximal end thereof to the shaft portion, the tip portion being non-planarly bent and/or curved and carrying markings, the number and scale of which are indicative of measured lengths

the probe being adapted at least by the number and/or scale of the markings for use in convenient gingival margin measurement of a tooth in a conscious non-human animal. A method for quantifying dental plaque in a conscious non-human animal comprising (a) aligning the tip portion of such a gingival contour probe with a gingival margin of a tooth in the animal

(b) by reference to the markings on the tip portion of the probe, measuring the length of the margin and the length of plaque deposit if any at the margin

and (c) calculating a plaque score for the tooth by comparing the length of plaque deposit with the length of the margin.

Priority: US20050727091P Applic. Date: 2005-10-14; WO2006US40383 Applic. Date: 2006-10-13

Inventor: SCHERL DALE SCOTT [US]; COFFMAN LORI [US]; RICHTER ROSE [US]; XU TAO [US]; BARNES VIRGINIA MONSUL [US]


Application No.: US20080254405A1  Published: 16/Oct/2008

Title: Method and device for improving oral health

Applicant/Assignee:

Application No.: 11/818590   Filing Date: 15/Jun/2007

Abstract:

The present invention relates to a method for improving the oral health of a subject by exposing the oral cavity of the subject to a device comprising a light source that emits a therapeutically effective amount of light. The present invention further relates to devices utilized in exposing light to the oral cavity of a subject in the method of the present invention.

Priority: US2006-344974 Applic. Date: 2006-02-01; US2005-044531 Applic. Date: 2005-01-26; US20060814239P Applic. Date: 2006-06-15; US20070892859P Applic. Date: 2007-03-04; US20050649402P Applic. Date: 2005-02-02

Inventor: MONTGOMERY R ERIC [US]; QUAN CHRISTOPHER [US]; ROSENBLOOD KENNETH [US]


Application No.: US20080254406A1  Published: 16/Oct/2008

Title: UNIVERSAL IMPRESSION TRAYS AND METHOD OF USE

Applicant/Assignee:

Application No.: 12/144787   Filing Date: 24/Jun/2008

Abstract:

A universal impression tray can be reshaped shortened or lengthened allowing a clinician the ability to use one tray in any clinical situation. The tray itself can be used with patients requiring complete removable dentures, root supported and implant-supported overdentures and in some selected dentate cases. The tray can be infinitely modified allowing total control by the clinician. Trays in accordance with features of the present invention are made of a material composition including thermoplastic resin and thermochromic pigment. The material composition softens and changes color in warm water but tends to hold its shape until manipulated by the dentist. The thermoplastic resin portion of the tray can include polycaprolactone resin, styrene resin and dental modeling compound and can vary for specific uses to roughly 50% polycaprolactone /styrene resin and 50% dental modeling compound. Thermochromic pigment can represent up to 5% of the overall material composition of a tray.

Priority: US2005-256519 Applic. Date: 2005-10-20; US20040621026P Applic. Date: 2004-10-20

Inventor: WAGNER STEPHEN [US]


Application No.: US20080254444A1  Published: 16/Oct/2008

Title: Immunoassay Devices and Use Thereof

Applicant/Assignee: CHEMBIO DIAGNOSTIC SYSTEMS, INC

Application No.: 12/138963   Filing Date: 13/Jun/2008

Abstract:

An immunoassay device has a housing defining a first opening for receiving a solution and a second opening through which a liquid sample is deposited, a strip of sorbent material having a test site with immobilized antigen or antibody for the ligand to be tested, and a filter for filtering the sample. The filter is located at the second opening and directly above the test site. The sorbent material defines a horizontal flow path in the housing for the solution from the first opening to the test site. In use, the sample is first applied via the filter to the test site, and then, after the ligand has been captured, a buffer added through the first opening is used to cause a secondary specific binder conjugated to a marker to migrate horizontally by capillary action to the test site where it can bind to the already captured ligand.

This immunoassay offer several advantages over the traditional chromatographic immunoassays.

Priority: US2004-014140 Applic. Date: 2004-12-16

Inventor: ESFANDIARI JAVANBAKHSH [US]


Application No.: US20080255247A1  Published: 16/Oct/2008

Title: Oil-In-Water Emulsion and Its Use for the Delivery of Functionality

Applicant/Assignee: NESTEC S.A

Application No.: 12/093560   Filing Date: 22/Nov/2006

Abstract:

The present invention concerns an oil-in-water emulsion wherein the oil droplets of a diameter in the range of 5 nm to hundreds of micrometers exhibit a nano-sized self-assembled structurization with hydrophilic domains having a diameter size in the range of 0.5 to 200 nm, due to the presence of a lipophilic additive and the oil-in-water emulsion contains an active element being present in the range comprised between 0.00001 and 79% based on the total composition.

Priority: EP20050025439 Applic. Date: 2005-11-22; WO2006EP68761 Applic. Date: 2006-11-22

Inventor: SAGALOWICZ LAURENT [CH]; LESER MARTIN [CH]; MICHEL MARTIN [CH]; WATZKE HERIBERT JOHANN [CH]; ACQUISTAPACE SIMONE [CH]; BERTHOLET RAYMOND [CH]; HOLST BIRGIT [CH]; ROBERT FABIEN [FR]


Application No.: US20080255265A1  Published: 16/Oct/2008

Title: Glass Filler Material and Method of Production

Applicant/Assignee:

Application No.: 10/596722   Filing Date: 22/Dec/2004

Abstract:

The present invention relates to a glass filler material with an average particle size of 0.1-20 mum. It further relates to a method for producing a glass filler material. The glass filler material comprises 65-99.95 mol % silicon dioxide (SiO2), 0-15 mol % aluminum and/or boron oxide (Al2O3, B2O3), 0-30 mol % zirconium and/or titanium and/or hafnium oxide (ZrO2, TIO2, HfO2), Y2O3 and/or Sc2O3 and/or La2O3 and/or CeO2 and/or other lanthanide oxides, 0.05-4 mol % alkali metal oxides (Na2O, Li2O, K2O, Rb2O, Cs2O), 0-25 mol % earth alkali metal oxides (MgO, CaO, SrO, BaO). The glass filler material shows a low concentration of alkali ions and is used for composites with cationically curing properties and for dental composites and dental restoration materials.

Priority: EP20030029538 Applic. Date: 2003-12-22; WO2004EP14614 Applic. Date: 2004-12-22

Inventor: HOESCHELER STEFAN [DE]; ALBRECHT DIRK [DE]; STIPPSCHILD ANDREA [DE]; DEDE KARSTEN [DE]


Application No.: US20080255266A1  Published: 16/Oct/2008

Title: DENTAL PASTE COMPOSITION HAVING X-RAY IMAGING PROPERTY

Applicant/Assignee: GC CORPORATION

Application No.: 11/733386   Filing Date: 10/Apr/2007

Abstract:

For easier removal after X-ray imaging, simple application, and excellent X-ray imaging properties, a dental paste composition having X-ray imaging property comprises: (a) 3 to 25 wt % of polyhydric alcohol

(b) 0.5 to 10 wt % of a powdery high polymer material dissolved and swelled in the polyhydric alcohol and water

(c) 10 to 30 wt % of water

and (d) 25 to 80 wt % of a powdery X-ray imaging material, the total weight of the polyhydric alcohol (a) and water (c) is 3 to 25 times of the weight of the powdery high polymer material (b), and the composition can be added with (e) 0.01 to 5 wt % of a fluorine compound, and (f) 15 wt % or less of an additive which is one or more kinds selected from a cushion material, a sweetener, a colorant, a preservative, an antiseptic agent, a fungicide, a pH regulator, an expander, and a perfume.

Priority:

Inventor: WALSH LAURENCE J [AU]; KATO SHINICHI [JP]; KARIYA SHUJI [JP]; SATO TAKUYA [JP]


Application No.: US20080255536A1  Published: 16/Oct/2008

Title: Methods and apparatuses for treating tonsils

Applicant/Assignee:

Application No.: 12/009957   Filing Date: 22/Jan/2008

Abstract:

Methods and apparatuses include applying a biting force to a bite-piece, the biting force is applied by a user's teeth, wherein the bite-piece is held inside of the user's mouth. Closing the mouth and the biting force suppress the user's gag reflex and the user's Tonsils and adjacent Throat structures can be treated by spraying fluid onto the Tonsil or manipulating the surface of the Tonsil and related structures. The Tonsils can be cleaned thereby.

Priority: US20070881861P Applic. Date: 2007-01-23

Inventor: MORELOCK MICHAEL DENNIS [US]; MORELOCK DAVID MICHAEL [US]


Application No.: US20080256725A1  Published: 23/Oct/2008

Title: Method for Colouring Toothbrush Filaments

Applicant/Assignee:

Application No.: 12/067695   Filing Date: 12/Sep/2006

Abstract:

A method of applying a consumable, in particular a wear indicator dye, to toothbrush filaments and/or other wearing parts for personal needs, in which the consumable is added to a medium which is subjected to pressure above atmospheric, and the toothbrush filaments and/or the wearing part are exposed to the pressurized mixture of consumable and medium for a predetermined exposure period. The medium to which the consumable is added includes CO2 as an essential constituent. The mixture of consumable and CO2 can be circulated in a pressure vessel under high pressure, so that the mixture is caused to flow around the toothbrush filaments or the corresponding wearing part.

Priority: DE200510045501 Applic. Date: 2005-09-23; WO2006EP08841 Applic. Date: 2006-09-12

Inventor: EMGE THORSTEN [DE]


Application No.: US20080256729A1  Published: 23/Oct/2008

Title: Teeth Whitening Toothbrush

Applicant/Assignee:

Application No.: 11/737785   Filing Date: 20/Apr/2007

Abstract:

A toothbrush for enhancing the whiteness of teeth while carrying out normal prophylactic brushing with a material that includes a light/heat activated whitening agent. The whitening agent is usually activated by light of a certain wavelength. The toothbrush comprises a handle and a head and optical transmission material bringing light of a predetermined frequency to the head portion. The head portion has a clear surface into which the bristles are secured so as to cause light to shine on the teeth surfaces as they are being brushed by the bristles.

Priority:

Inventor: LINK JOHN [US]


Application No.: US20080256745A1  Published: 23/Oct/2008

Title: Moquette carpet cleaning machine operable in pull-back mode

Applicant/Assignee: SANTOEMMA S.R.L

Application No.: 12/082914   Filing Date: 15/Apr/2008

Abstract:

The present invention refers to a moquette carpet cleaning machine ( 10 ) operable in pull-back mode comprising a machine body ( 11 ) provided with main rear wheels ( 12 ) and a suction mouth ( 14 ) placed at the front and is characterised in that support means ( 19 ) are constrained to the machine ( 10 ), on which support means ( 19 ) at least one auxiliary wheel ( 16 ) is mounted, and in that at least one from among the main wheels ( 12 ), suction mouth ( 14 ), the at least one auxiliary wheel ( 16 ) and support means ( 19 ) are movable means with respect to the machine body ( 11 ), between at least a first (A) and at least a second (B) relative position such that, when the movable means ( 12,14,19,16 ) are in the first relative position (A), the suction mouth ( 14 ) is maintained adherent to the ground ( 20 ), and when the movable means ( 12,14,19,16 )

are in the second relative position (B), the suction mouth ( 14 ) is maintained substantially raised from the ground ( 20 ).

Priority: IT2007MI00836 Applic. Date: 2007-04-20

Inventor: SANTOEMMA NICOLA [IT]; SANTOEMMA MASSIMILIANO [IT]


Application No.: US20080257109A1  Published: 23/Oct/2008

Title: High Vacuum In-Situ Refining Method for High-Purity Materials and an Apparatus Thereof

Applicant/Assignee: THE CHINESE ACADEMY OF SCIENCES INSTITUTE OF PHYSICS

Application No.: 12/067835   Filing Date: 11/Apr/2006

Abstract:

The present invention concerns a high vacuum in-situ refining method for high-purity and superhigh-purity materials and the apparatus thereof, characterized in heating the upper part and lower part of crucible separately using double-heating-wires diffusion furnace under vacuum, thereby forming the temperature profile which is high at upper part and low at lower part of crucible, or in reverse during different stages

then heating the crucible in two steps to remove impurities with high saturation vapor pressure and low saturation vapor pressure respectively in efficiency

and obtaining high-purity materials eventually. The whole procedure is isolated from atmosphere, reducing contamination upon stuff remarkably.

The present invention could provide products with high-quality and high production capacity, which are stable in performance, therefore is reliable and free from contamination. The present invention is appropriate for manufacture of high-purity and superhigh-purity materials, particularly for manufacture of high-activity high-purity materials.

Priority: CN20051105454 Applic. Date: 2005-09-28; CN20051105687 Applic. Date: 2005-09-30; WO2006CN00645 Applic. Date: 2006-04-11

Inventor: DU XIAOLONG [CN]; ZENG ZHAOQUAN [CN]; YUAN HONGTAO [CN]; LI HANDONG [CN]; XUE QIKUN [CN]; JIA JINFENG [CN]


Application No.: US20080257384A1  Published: 23/Oct/2008

Title: Bucket Arrangement and Method of Using the Same

Applicant/Assignee:

Application No.: 11/884626   Filing Date: 25/Jan/2006

Abstract:

An improved apparatus and a method of using the apparatus for cleaning tools, utensils, and other objects. The apparatus comprises a container, a first wiping element that is submerged in a liquid in the container capable of removing undesirable material from at least a portion of the object and a second wiping element mountable to the container that is capable of removing excess moisture from the object. The object undergoes at least a two-step wiping comprising a first wiping against the first wiping element while submerged in the liquid and a second wiping against the second wiping element after being at least partially removed from the liquid. The apparatus of the invention reduces the potential for serious injuries from cuts or abrasions from contact with the objects and is more sanitary than systems currently used in the prior art. The apparatus of the invention may also be easily disassembled for cleaning.

Priority: US20050653882P Applic. Date: 2005-02-16; WO2006US02551 Applic. Date: 2006-01-25

Inventor: FARRELL CHRISTOPHER P [US]


Application No.: US20080258392A1  Published: 23/Oct/2008

Title: Game simulating the catching of fish by plug casting

Applicant/Assignee:

Application No.: 11/903701   Filing Date: 25/Sep/2007

Abstract:

A fishing apparatus comprising a flat, essentially vertical game board, a fish support mounted behind the game board, one or more flat, relatively thin fish-shaped members releasably mounted on the fish support, each fish-shaped member having a tapered mouth at on end thereof and a circular snare opening connecting to the mouth through a guide slot, a casting line, a plug adapted to be connected to the end of the casting line so that the plug and line can be cast over the fish-shaped members, each plug being made of resilient material and being provided with a nose piece adjacent to the connection of the line to the plug, the nose piece being receivable in the snare opening, the game board having a gap therein which is in alignment with the guide slot in the fish-shaped member,

the gap in the game board being associated with a plurality of doors which are mounted on hinge axes for swinging movement when a fish-shaped member is pulled against the doors, whereby, when the plug is pulled into the circular snare opening and the line is pulled thereafter, the fish-shaped member will spring out through the hinged doors in a manner simulating the catching of fish in actual water.

Priority: US2007-788271 Applic. Date: 2007-04-19

Inventor: LOWRANCE ARLEN J [US]


Application No.: US20080260652A1  Published: 23/Oct/2008

Title: COMPOSITION FOR DYEING DENTAL PLAQUE FOR EVALUATING DENTAL CARIES ACTIVITY

Applicant/Assignee: GC CORPORATION

Application No.: 12/143290   Filing Date: 20/Jun/2008

Abstract:

An objective of the present invention is to provide a composition for dyeing dental plaque for evaluation of dental caries activity that is capable of simultaneously dyeing dental plaque and evaluating dental caries activity, and which can evaluate thick dental plaque more accurately than the conventional technique. The composition for dyeing dental plaque for evaluation dental caries activity comprises: a blue pigment being dissolved in water and having a color tone not changing at pH 7 or less

a red pigment being dissolved in water at pH more than 4.5 but not dissolved in water at pH 4.5 or less, and having a color tone not changing at pH 4.5 or less

and sugar. The content of sugar is preferably 1 to 50 weight parts to the total of 1 weight part of contents of the blue pigment and the red pigment, and ratio of contents of the blue pigment and the red pigment is preferably 1:3 to 3:1.

Priority: US2007-733387 Applic. Date: 2007-04-10

Inventor: WALSH LAURENCE J [AU]; OTA RYOKO [JP]; NAGAO SAYAKA [JP]; SATO TAKUYA [JP]


Application No.: US20080260660A1  Published: 23/Oct/2008

Title: Teeth Whitening Agents

Applicant/Assignee:

Application No.: 11/793323   Filing Date: 16/Dec/2005

Abstract:

The invention relates to light-activated teeth whitening compositions, and to the use thereof for lightening teeth. The inventive whitening agent contains riboflavin and or the derivatives thereof, which enable the oxidant in the whitening agent to decompose more rapidly, by means of radiation energy, thus effectively accelerating the whitening action. The invention especially relates to single-constituent or dual-constituent materials that have a stable pasty form and can be optionally additionally chemically activated.

Priority: DE200410061646 Applic. Date: 2004-12-17; WO2005EP13587 Applic. Date: 2005-12-16

Inventor: ENGELBRECHT JURGEN [DE]; GOLICH J K [DE]


Application No.: US20080260817A1  Published: 23/Oct/2008

Title: Compositions for the Treatment of Inflammation and Pain Using a Combination of a Cox-2 Selective Inhibitor and a Ltb4 Receptor Antagonist

Applicant/Assignee:

Application No.: 10/597646   Filing Date: 08/Jul/2008

Abstract:

The present invention provides a therapeutic composition comprising a COX-2 selective inhibitor or a prodrug thereof and an LTB4 receptor antagonist. A method is provided for the use of such composition in the treatment, prevention, or inhibition of inflammation, an inflammation-related disorder, pain, or a pain-related disorder.

Priority: US20040590076P Applic. Date: 2004-07-22; WO2005IB02203 Applic. Date: 2005-07-11

Inventor: PATEL PHENIL JAYANTILAL [US]; CHAING PO-CHANG [US]


Application No.: US20080260830A1  Published: 23/Oct/2008

Title: Growth Factor Mutants With Improved Biological Activitiy

Applicant/Assignee: CHARITE- UNIVERSITAETSMEDIZIN BERLIN FREIE UNIVERSITAET BERLIN BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWI

Application No.: 11/817735   Filing Date: 03/Mar/2006

Abstract:

The invention relates to novel biosynthetic growth factor mutants which exhibit improved biological activity.

Priority: EP20050004840 Applic. Date: 2005-03-04; WO2006EP01966 Applic. Date: 2006-03-03

Inventor: MUNDLOS STEFAN [DE]; KNAUS PETRA [DE]; POHL JENS [DE]; KRUSE MICHAEL [DE]; PLOGER FRANK [DE]


Application No.: US20080261178A1  Published: 23/Oct/2008

Title: PROCESS FOR PROVIDING A TOPOGRAPHY TO THE SURFACE OF A DENTAL IMPLANT

Applicant/Assignee: STRAUMANN HOLDING AG

Application No.: 12/105595   Filing Date: 18/Apr/2008

Abstract:

A process for providing a topography to the surface of a dental implant, said surface being made of a ceramic material. At least a part of the surface of the dental implant is etched with an etching solution comprising hydrofluoric acid at a temperature of at least 70 DEG C. Thereby, discrete grains or agglomerates of grains are removed from the ceramic material.

Priority: EP20070007949 Applic. Date: 2007-04-19

Inventor: HOMANN FRANK [DE]; HABERSETZER PHILIPPE [FR]


Application No.: US20080261179A1  Published: 23/Oct/2008

Title: DENTAL IMPLANT HAVING A SURFACE MADE OF A CERAMIC MATERIAL

Applicant/Assignee: STRAUMANN HOLDING AG

Application No.: 12/105700   Filing Date: 18/Apr/2008

Abstract:

A dental implant having a surface made of a ceramic material. The dental implant is characterized in that the surface has a topography defined by a Core Roughness Depth Sk of less than 1 mum.

Priority: EP20070007950 Applic. Date: 2007-04-19

Inventor: DE WILD MICHAEL [CH]; HOMANN FRANK [DE]


Application No.: US20080261865A1  Published: 23/Oct/2008

Title: Oxidized Lipids and Uses Thereof in the Treatment of Inflammatory Diseases and Disorders

Applicant/Assignee:

Application No.: 10/567543   Filing Date: 27/May/2004

Abstract:

Novel synthetic oxidized lipids and methods utilizing oxidized lipids for treating and preventing an inflammation associated with an endogenous oxidized lipid are provided.

Priority: US2003-445347 Applic. Date: 2003-05-27; WO2004IL00453 Applic. Date: 2004-05-27

Inventor: HARATS DROR [IL]; GEORGE JACOB [IL]; HALPERIN GIDEON [IL]


Application No.: US20080261960A1  Published: 23/Oct/2008

Title: Biologically active methylene blue derivatives

Applicant/Assignee: PHOTOPHARMICA LIMITED

Application No.: 12/078805   Filing Date: 04/Apr/2008

Abstract:

The present invention relates to a phenothiazinium compound of Formula (I): wherein: A and B each independently is in which R' and R'' each independently is a linear, branched or cyclic hydrocarbon group, or R' and R'' together with the N atom to which they are attached form an optionally substituted 5-, 6- or 7-membered ring

and where Xis a counteranion and P is 1, 2 or 3

except for the compounds in which A and B are both either -N(CH3)2 or -N(CH2CH3)2 for use in a treatment that requires removal, deactivation or killing of unwanted tissues or cells. The invention also relates to compositions comprising the compounds of Formula I, to selected compounds of Formula I, use of the compounds of Formula I as medicaments and as a PDT agent or a photodiagnostic agent, a conjugate or composite formed between a compound of Formula I and a polymer

and to a method for sterilising fluids in which the fluid is passed over the conjugate or composite whilst it is illuminated. The compounds are biologically active photosensitisers which are strongly photocytotoxic and have application in the areas of photodynamic therapy (PDT), as well as for the diagnosis and detection of medical conditions and related uses in photochemical internalisation, in the production of cancer vaccines, in the treatment and prevention of microbial infections and in photodisinfection or photosterilisation.

Priority: GB20010013121 Applic. Date: 2001-05-30; GB20010023945 Applic. Date: 2001-10-05; US2003-723420 Applic. Date: 2003-11-26; WO2002GB02278 Applic. Date: 2002-05-30

Inventor: BROWN STANLEY BEAMES [GB]; O'GRADY CASSANDRA CLAIRE [GB]; GRIFFITHS JOHN [GB]; MELLISH KIRSTE JOANNE [GB]; TUNSTALL RICHARD GEORGE [GB]; ROBERTS DAVID JOHN HOWARD [GB]; VERNON DAVID IAN [GB]


Application No.: US20080262370A1  Published: 23/Oct/2008

Title: Gas sensor

Applicant/Assignee: ANAXSYS TECHNOLOGY LIMITED

Application No.: 12/081113   Filing Date: 10/Apr/2008

Abstract:

A method of determining the respiratory function of a subject is disclosed, the method comprising measuring the concentration of water vapour in the gas stream exhaled by the subject, and from the measured water vapour concentration determining the respiratory function of the subject. Mathematical techniques for analyzing the data obtained from the measurement of concentrations of gaseous components in an exhaled gas stream are also disclosed and their use in determining the lung function of a subject.

Priority: GB20060020711 Applic. Date: 2006-10-18; GB20070009439 Applic. Date: 2007-05-17; WO2007GB03957 Applic. Date: 2007-10-17

Inventor: VARNEY MARK SINCLAIR [GB]; GARRETT MICHAEL [GB]; WILLIAMS DERYK JOHN PETER [GB]


Application No.: US20080262428A1  Published: 23/Oct/2008

Title: METHOD FOR VAP PREVENTATIVE VENTILATION OF INTUBATED CRITICALLY ILL PATIENTS

Applicant/Assignee: KIMBERLY-CLARK WORLDWIDE, INC

Application No.: 11/736816   Filing Date: 18/Apr/2007

Abstract:

An intermittent, large-volume lavage/suctioning scheme is provided. A lavage solution is first applied into the subglottic cavity, in sufficient volume to mechanically dislodge and wash-out pooled contaminated solid materials from the oro-pharyngeal spaces, the naso-pharyngeal spaces and the sinuses adjunct to the intra-nasal cavities. The dislodged contaminated solid materials are removed with large bore suctioning tools suited for atraumatic, deep naso-pharyngeal and oro-pharyngeal insertion. After the suctioning procedure has been performed, a space filling gel seal that is composed of a self-degrading physiologic substance can be installed within the subglottic space and subsequently washed out into the pharynx with the next lavage procedure. The lavage/suctioning scheme largely reduces or eliminates a bacteria colonization pattern where VAP causing pathogens have been.

Priority:

Inventor: GOBEL FRED G [DE]


Application No.: US20080267891A1  Published: 30/Oct/2008

Title: Oral Care Composition To Reduce Or Eliminate Dental Sensitivity

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/103919   Filing Date: 16/Apr/2008

Abstract:

The invention includes an oral care composition that reduces and/or eliminates the perception of tooth sensitivity. The composition includes an adherent material and particles having an average particle size of about 8 microns or less. The particles are present in the composition in an amount of about 5% by weight. Also included within the scope of the invention are related methods, such as methods of occluding a dentin tubule.

Priority: US2007-742039 Applic. Date: 2007-04-30

Inventor: ZAIDEL LYNETTE [US]; CHOPRA SUMAN K [US]; PRENCIPE MICHAEL [US]; WANG QIN [US]; CHRISTOPOULOU CONSTANTINA [US]


Application No.: US20080268001A1  Published: 30/Oct/2008

Title: ORAL CARE COMPOSITION TO REDUCE OR ELIMINATE DENTAL SENSITIVITY

Applicant/Assignee:

Application No.: 11/742039   Filing Date: 30/Apr/2007

Abstract:

The invention includes an oral care composition that reduces and/or eliminates the perception of tooth sensitivity. The composition includes an adherent material and silica particles having an average particle size of about 8 microns or less. The silica particles are present in the composition in an amount of about 5% by weight. Also included within the scope of the invention are related methods, such as methods of occluding a dentin tubule.

Priority:

Inventor: ZAIDEL LYNETTE [US]; CHOPRA SUMAN K [US]; PRENCIPE MICHAEL [US]; WANG QIN [US]; CHRISTOPOULOU CONSTANTINA [US]


Application No.: US20080268037A1  Published: 30/Oct/2008

Title: Autonomous method for oral delivery of a healing substance to a target place in gastrointestinal tract of humans or animals

Applicant/Assignee:

Application No.: 11/789108   Filing Date: 24/Apr/2007

Abstract:

A method for oral delivery of new drugs, big molecules, proteins, and healing substances to a target place in the body, via digestive tract, using mobile self-controlled capsules with sensors.

Priority:

Inventor: STUKANOV IGOR IGOREVICH [CA]


Application No.: US20080269152A1  Published: 30/Oct/2008

Title: Nucleic acid binding oligonucleotides

Applicant/Assignee: LICENSING & INDUSTRY SPONSORED RESEARCH

Application No.: 11/904612   Filing Date: 26/Sep/2007

Abstract:

The present application pertains to products and methods related to the ability of short nucleotide oligomers to bind the tertiary or globular structure of nucleic acids. This application discloses libraries of short oligomers and methods for using these libraries.

Priority: US2004-977990 Applic. Date: 2004-10-29; US20030516243P Applic. Date: 2003-10-31

Inventor: VERDINE GREGORY L [US]; SANTOS WEBSTER [US]


Application No.: US20080269191A1  Published: 30/Oct/2008

Title: Compounds for Nonsense Suppression, Use of These Compounds for the Manufacture of a Medicament for Treating Somatic Mutation-Related Diseases

Applicant/Assignee: PTC THERAPEUTICS, INC

Application No.: 11/577176   Filing Date: 13/Oct/2005

Abstract:

The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.

Priority: US20040617670P Applic. Date: 2004-10-13; US20040617633P Applic. Date: 2004-10-13; US20040617655P Applic. Date: 2004-10-13; US20040617634P Applic. Date: 2004-10-13; US20040617653P Applic. Date: 2004-10-13; US20040624170P Applic. Date: 2004-11-03; WO2005US36762 Applic. Date: 2005-10-13

Inventor: WILDE RICHARD [US]; WELCH ELLEN [US]; KARP GARY M [US]


Application No.: US20080269223A1  Published: 30/Oct/2008

Title: Mouth Dissolvable and Meltable, and Water Dispersable Delivery Formulation

Applicant/Assignee:

Application No.: 11/547297   Filing Date: 04/Apr/2005

Abstract:

A mouth dissolvable and meltable, and water dispersable delivery system for oral administration consisting of an antiepileptic drug, one or more swelling agents, one or more of fillers, one or more of disintegrating agents, and one or more of binders is disclosed. The swelling agent is powdered cellulose, filler is spray dried mannitol, disintegrating agent is crosslinked polyvinyl pyrrolidone and binder is maltodextrin. This system optionally comprises one or more of other excipients selected from the group comprising lubricants, sweetners and flavouring agent.

Priority: IN2004MU00419 Applic. Date: 2004-04-06; WO2005IN00101 Applic. Date: 2005-04-04

Inventor: CHAKRAVORTY SAIBAL [IN]; HARIHARAN V [IN]


Application No.: US20080269229A1  Published: 30/Oct/2008

Title: Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Applicant/Assignee:

Application No.: 12/216213   Filing Date: 01/Jul/2008

Abstract:

This invention relates to novel 8-aza-bicyclo[3.2.1]octane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20030000939 Applic. Date: 2003-06-24; DK20030001487 Applic. Date: 2003-10-09; DK20040000228 Applic. Date: 2004-02-13; US2005-561417 Applic. Date: 2005-12-19; WO2004EP51167 Applic. Date: 2004-06-18; US20030482566P Applic. Date: 2003-06-26; US20030509808P Applic. Date: 2003-10-10; US20040544210P Applic. Date: 2004-02-13

Inventor: PETERS DAN [DK]; ERIKSEN BIRGITTE L [DK]; NIELSEN ELSEBET OSTERGAARD [DK]; SCHEEL-KRUGER JERGEN [DK]; OLSEN GUNNAR M [DK]


Application No.: US20080269253A1  Published: 30/Oct/2008

Title: Substituted Benzofused Derivatives and Their Use as Vanilloid Receptor Ligands

Applicant/Assignee: GLENMARK PHARMACEUTICALS, S.A GLENMARK PHARMACEUTICALS S.A

Application No.: 12/067879   Filing Date: 09/Oct/2006

Abstract:

The present invention relates to substituted benzofused derivatives, which can be used as vanilloid receptor ligands, method of treating diseases, conditions and/or disorders modulated by vanilloid receptors with them, and processes for preparing them.

Priority: IN2005MU01269 Applic. Date: 2005-10-07; US20050730660P Applic. Date: 2005-10-26; WO2006IB02814 Applic. Date: 2006-10-09; IN2006MU00996 Applic. Date: 2006-06-26; US20060807205P Applic. Date: 2006-07-13

Inventor: GHARAT LAXMIKANT ATMARAM [IN]; JOSHI UDAY MUKUND [IN]; JOSHI NEELIMA KHAIRATKAR [IN]


Application No.: US20080270175A1  Published: 30/Oct/2008

Title: Systems and methods using a dynamic expert system to provide patients with aesthetic improvement procedures

Applicant/Assignee: KLINGER ADVANCED AESTHETICS, INC

Application No.: 11/443104   Filing Date: 31/May/2006

Abstract:

The invention relates to dynamic expert systems to provide a patient with at least one recommendation on performing an aesthetic improvement procedure. The system includes a database with actual case studies and aesthetic improvement procedures. The system also includes software adapted to allow a user to query the database based on a patient's desired aesthetic improvement and the results of at least one diagnostic test performed on the patient. The aesthetic improvement procedure is performed and the results of at least one diagnostic test performed after the procedure are analyzed and added to the database of case studies substantially immediately after analysis. The system may also include software adapted to allow a user to query the database based on a patient's desired aesthetic improvement. The system may also include software adapted to query the database to find the results of at least one diagnostic test performed on a patient, to allow the addition of new case studies to the database, to allow the addition of new diagnostic tests, and to allow the addition of new aesthetic improvement procedures.

Priority: US2004-863856 Applic. Date: 2004-06-08; US20030533731P Applic. Date: 2003-12-31; US20060795156P Applic. Date: 2006-04-27

Inventor: RODRIGUEZ MICHAEL S [US]; RAKOWSKI RICHARD [US]; CHARRON KELLY [US]


Application No.: US20080271636A1  Published: 06/Nov/2008

Title: Composition for Dental Impression Treatment Material and Preparation Thereof

Applicant/Assignee:

Application No.: 11/720143   Filing Date: 28/Nov/2005

Abstract:

The present invention relates to a composition for dental impression treatment material and preparation thereof for the purpose of obtaining the superior impression in restoration treatment for dental prosthesis, and for the gingival retraction from the teeth, gingival oozing inhibition and stanching. The composition preferably comprises 67.70 to 71.85% by weight of kaolin clay, 16.05 to 20.00% by weight of distilled water, 10.83 to 11.50% by weight of aluminum chloride hexahydrate, 0.14 to 1.02% by weight of starch powder, 0.42 to 0.43% by weight of silicone oil, 0.03% by weight of coloring agent.

Priority: KR20040098616 Applic. Date: 2004-11-29; WO2005KR04015 Applic. Date: 2005-11-28

Inventor: KIM JAE-WON [KR]; HONG SEOK-JONG [KR]; KIM SUK-YOUNG [KR]


Application No.: US20080274062A1  Published: 06/Nov/2008

Title: Glycyrrhizic acid compounds as a foamer in chemically-derived surfactant-free dentifrice

Applicant/Assignee:

Application No.: 11/799523   Filing Date: 02/May/2007

Abstract:

The present invention relates to dentifrices in general and dentifrices free of chemically-derived foaming agents in particular. Particularly, the present invention relates to an all-natural dentifrice (e.g., toothpaste) comprising a concentration of glycyrrhizic acid that is suitable to work as a foaming agent. Even more particularly, the present invention relates to an all-natural dentifrice (e.g., toothpaste) that does not contain one or more of sodium lauryl sulfate, sodium lauroyl sarcosinate, cocomidopropyl betaine, sodium methyl cocoyl taurate, sodium cocoyl glutamate, poloxamer or any other chemically-derived foaming agent.

Priority:

Inventor: BERGERON CHANTAL [US]; VENELL JULIE [US]


Application No.: US20080274063A1  Published: 06/Nov/2008

Title: Supercritical CO2 liquorice extract anti-microbial and anti-inflammatory isolates and products made there from

Applicant/Assignee:

Application No.: 12/150920   Filing Date: 01/May/2008

Abstract:

The present invention provides, in one aspect, to products made from a novel and non-obvious supercritical CO2 extract of the roots of Glycyrrhiza sp., effective as an anti-inflammatory, anti-bacterial, anti-fungal and anti-adherent agent, including, but not limited to, products for oral care and body care. The present invention also provides, in another aspect, components isolated from the supercritical CO2 extract of the roots of Glycyrrhiza sp., effective as an anti-inflammatory, anti-bacterial, anti-fungal and anti-adherent agent, including, but not limited to, products for oral care and body care.

Priority: US2007-799524 Applic. Date: 2007-05-02

Inventor: BERGERON CHANTAL [US]; GAFNER STEFAN [US]


Application No.: US20080274064A1  Published: 06/Nov/2008

Title: UTILIZATION OF RHINOLOGICALLY ACTIVE SUBSTANCES

Applicant/Assignee: SYMRISE GMBH & CO. KG

Application No.: 12/175156   Filing Date: 17/Jul/2008

Abstract:

Acyclic compounds containing an ethers functionality external to the ring can be used as rhinologically active substances. In the regions of the mouth, the throat and the airways they produce a refreshing and clearing feeling.

Priority: DE20001058459 Applic. Date: 2000-11-24; US2003-626178 Applic. Date: 2003-07-24; US2001-988860 Applic. Date: 2001-11-21

Inventor: SURBURG HORST [DE]; MACHINEK ARNOLD [DE]; LOGES HUBERT [DE]


Application No.: US20080274066A1  Published: 06/Nov/2008

Title: Compositions, Methods, Devices, and Kits for Maintaining or Enhancing Tooth Whitening

Applicant/Assignee: BRITESMILE PROFESSIONAL, INC

Application No.: 10/568054   Filing Date: 28/Jul/2004

Abstract:

Compositions, methods, devices, and kits for maintaining or enhancing tooth whitening in a subject are disclosed. The methods include applying a first tooth whitening composition to the teeth of the subject for a predetermined period of time and applying a second tooth whitening composition to the teeth of the subject in predetermined intervals, wherein at least one of the first and second tooth whitening compositions are dispensed from a dental delivery device. The kits include a first tooth whitening composition and a second tooth whitening composition, each including an oxidizing agent. The oxidizing agent of the first tooth whitening composition is present in a higher amount than the second tooth whitening composition, which maintains or enhances the tooth whitening effect of the first tooth whitening composition.

Priority: US2003-670950 Applic. Date: 2003-09-25; US20030490654P Applic. Date: 2003-07-28; US20030495043P Applic. Date: 2003-08-14; US20030511462P Applic. Date: 2003-10-15; WO2004US24070 Applic. Date: 2004-07-28

Inventor: MONTGOMERY ROBERT ERIC [US]


Application No.: US20080274155A1  Published: 06/Nov/2008

Title: Chimeric Cannulae Proteins, Nucleic Acids Encoding Them And Methods For Making And Using Them

Applicant/Assignee: VERENIUM CORPORATION

Application No.: 10/593846   Filing Date: 24/Mar/2005

Abstract:

The invention provides chimeric cannulae polypeptides and nanotubules and methods for making and using them. In one aspect, the invention provides compositions and methods for the identification, separation or synthesis of proteins or ligands. In one aspect, the invention provides compositions and methods for making and using nanotubules. In one aspect, the invention provides compositions and methods for the selection and purification of chiral compositions from racemic mixtures. In one aspect, the chimeric proteins and polymers (e.g., nanotubules, tubules, bundles, balls, fibers, filaments, sheets, threads, textiles) of the invention comprise a detectable moiety, e.g., a fluorescent protein. In one aspect, the invention provides a flame retardant or heat resistant device comprising a sheeting, a covering, a coating or an adhesive comprising a chimeric protein of the invention.

Priority: US20040556393P Applic. Date: 2004-03-24; US20040605192P Applic. Date: 2004-08-27; WO2005US09927 Applic. Date: 2005-03-24

Inventor: BARTON NELSON R [US]; O'DONOGHUE EILEEN [US]; SHORT RYAN [US]; FREY GERHARD [US]; WEINER DAVID [US]; ROBERTSON DAN E [US]; BRIGGS STEVEN [US]; ZORNER PAUL [US]


Application No.: US20080274156A1  Published: 06/Nov/2008

Title: Composition forstimulating bone growth and differentiation and method for isolating same

Applicant/Assignee: THE UNIVERSITY OF QUEENSLAND

Application No.: 12/012860   Filing Date: 05/Feb/2008

Abstract:

This invention relates to isolated heparan sulphate and use thereof to stimulate bone cell growth and differentiation. The invention also relates to use of heparan sulphate with implants, prosthesis and bioscaffolds to repair and regenerate bone. Such use may be for repair of damaged tissue including bone tissue, for example damage resulting from injury or defect.

Priority: US2005-123897 Applic. Date: 2005-05-06

Inventor: NURCOMBE VICTOR [SG]; COOL SIMON [SG]


Application No.: US20080274179A1  Published: 06/Nov/2008

Title: Supercritical CO2 liquorice extract and products made there from

Applicant/Assignee:

Application No.: 11/799524   Filing Date: 02/May/2007

Abstract:

The present invention provides, in one aspect, to products made from a novel and non-obvious supercritical CO2 extract of the roots of Glycyrrhiza sp., effective as an anti-inflammatory, anti-bacterial, anti-fungal and anti-adherent agent, including, but not limited to, products for oral care and body care.

Priority:

Inventor: BERGERON CHANTAL [US]; GAFNER STEFAN [US]


Application No.: US20080274188A1  Published: 06/Nov/2008

Title: Oral Vehicle For Systemic Pharmaceuticals

Applicant/Assignee: PBL MANUFACTURING LIMITED

Application No.: 12/067817   Filing Date: 22/Sep/2006

Abstract:

Systemic drug delivery includes boluses of a semi-solid agar gel, each containing active ingredients, packed singly or in co-operating sets in blister packs, or loose in a container. When placed in the mouth the bolus is disrupted, comes apart, and releases the active ingredients. Sialogogues, flavours, and other additives assist in swallowing. Grains of the active ingredients may be encapsulated inside harder gel capsules. Active ingredients include over-the-counter medications and prescription medications. Applications include self-medication particularly in water-free situations such as public transport, medication for children, stroke victims or the aged.

Priority: GB20050019290 Applic. Date: 2005-09-22; WO2006NZ00246 Applic. Date: 2006-09-22

Inventor: ALEXANDER CARL ERNEST [NZ]


Application No.: US20080274439A1  Published: 06/Nov/2008

Title: Dental device for use in the obturation of a root canal

Applicant/Assignee:

Application No.: 11/890411   Filing Date: 06/Aug/2007

Abstract:

Kit-of-parts containing (i) a dental device for use in the obturation of a root canal which comprises a tapered obturating point portion integrally connected at the distal end of a functional portion, whereby the functional portion comprises (a) a neck portion adjacent to the obturating point portion, and (b) a handle portion, and (ii) a dental sealant composition, wherein the dental device is made of a material obtainable by curing a composition containing one or more curable components contained in the dental sealant.

Priority: WO2006EP00963 Applic. Date: 2006-02-03; EP20050002423 Applic. Date: 2005-02-04; EP20060706627 Applic. Date: 2006-02-03

Inventor: GUTZNER ANDREAS E [DE]; KLEE JOACHIM E [DE]


Application No.: US20080274442A1  Published: 06/Nov/2008

Title: Laser curable polymerisable composition for the protection of hard tissue

Applicant/Assignee:

Application No.: 12/215821   Filing Date: 30/Jun/2008

Abstract:

One-component heat-curable sealant composition for the protection of exposed dental surfaces, comprising (a) a polymerisable monomer and/or oligomer which has at least two polymerizable double bonds per molecule, and (b) an initiator system comprising benzoylperoxide in an amount of at least 2 wt.-% based on the total composition.

Priority: EP20040018112 Applic. Date: 2004-07-30; WO2005EP08268 Applic. Date: 2005-07-29; US2006-387177 Applic. Date: 2006-03-23

Inventor: KLEE JOACHIM E [DE]; FACHER ANDREAS [DE]; WEBER CHRISTOPH [DE]; MULHAUPT ROLF [DE]; SCHMIDER MARTIN [DE]


Application No.: US20080275037A1  Published: 06/Nov/2008

Title: 2-Cyanophenyl fused heterocyclic compounds, and compositions and uses thereof

Applicant/Assignee:

Application No.: 12/080253   Filing Date: 31/Mar/2008

Abstract:

Fused heterocyclic compounds are provided according to formula 1: where R<1>, R<2>, R<3>, and m are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.

Priority: US20070925109P Applic. Date: 2007-04-17; US20080010512P Applic. Date: 2008-01-08

Inventor: WEI ZHI-LIANG [US]; O'MAHONY DONOGH JOHN ROGER [US]; DUNCTON MATTHEW [US]; KINCAID JOHN [US]; KELLY MICHAEL G [US]; WANG ZHAN [US]


Application No.: US20080275079A1  Published: 06/Nov/2008

Title: M3 Muscarinic Acetylcholine Receptor Antagonists

Applicant/Assignee: GLAXO GROUP LIMITED

Application No.: 11/997466   Filing Date: 02/Aug/2006

Abstract:

Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.

Priority: US20050704579P Applic. Date: 2005-08-02; WO2006US30153 Applic. Date: 2006-08-02

Inventor: BUSCH-PETERSEN JAKOB [US]; LAINE DRAMANE IBRAHIM [US]; PALOVICH MICHAEL R [US]; DAVIS RODERICK S [US]; FU WEI [US]; XIE HAIBO [US]


Application No.: US20080275482A1  Published: 06/Nov/2008

Title: Facial Lift

Applicant/Assignee:

Application No.: 12/038817   Filing Date: 28/Feb/2008

Abstract:

A facial lift device to be placed behind the lips and above the gums disposed alongside the buccal and facial surface of a living human maxilla or a human mandible no further than the most posterior tooth of one side to the most posterior tooth of the opposite side of said maxilla or mandible. The facial device embodies an outward lifting force when placed within the human mouth under the lips and alongside the anterior vestibule centered on the frenulum, such that when said facial lift device is forced behind the maxilla or mandible lips, the facial lift will forcibly lift out the dermal layer reducing and removing lower facial wrinkles within the perioral region.

Priority: US20070904342P Applic. Date: 2007-02-28

Inventor: BRUCE CRAIG A [US]


Application No.: US20080275484A1  Published: 06/Nov/2008

Title: Per Os Placement of Extragastric Devices

Applicant/Assignee:

Application No.: 12/168134   Filing Date: 06/Jul/2008

Abstract:

Methods and devices to externally create a restriction on the stomach are described. In some embodiments, the devices are contoured to fit the stomach and can be further anchored to the stomach. In further embodiments, the degree of deployment of the extragastric restriction device is controllable after implantation. In other embodiments, specialized wires, catheters, ports, and trocars specific for placement of extragastric restriction devices are presented. In still further embodiments, systems are described in which adjustability of the devices is provided along with sensing and actuating ability.

Priority: US2006-395302 Applic. Date: 2006-03-31; US2006-334105 Applic. Date: 2006-01-17; US2005-295281 Applic. Date: 2005-12-06; WO2005US33683 Applic. Date: 2005-09-19; US2005-148519 Applic. Date: 2005-06-09; US2005-153791 Applic. Date: 2005-06-15; US2005-125547 Applic. Date: 2005-05-10; WO2005US09322 Applic. Date: 2005-03-19; US2004-974248 Applic. Date: 2004-10-27; US20040556004P Applic. Date: 2004-03-23; US20040584219P Applic. Date: 2004-07-01; US20040603944P Applic. Date: 2004-08-23

Inventor: GERTNER MICHAEL [US]


Application No.: US20080276948A1  Published: 13/Nov/2008

Title: Chewing article for oral tobacco delivery

Applicant/Assignee: PHILIP MORRIS USA INC

Application No.: 12/149716   Filing Date: 07/May/2008

Abstract:

A chewing article for oral tobacco delivery includes a mouth portion and a handle portion. Preferably, the mouth portion includes a mouthpiece containing tobacco material and a cap. The mouthpiece includes at least one perforation that selectively releases the enclosed tobacco material when chewed, sucked, or manipulated. The handle portion is attached to the mouth portion.

Priority: US20070924313P Applic. Date: 2007-05-09

Inventor: GEDEVANISHVILI SHALVA [US]; GEIB DENNIS [US]; WAYMACK BRUCE [US]; BROOKS KAREN [US]; SWEENEY WILLIAM R [US]


Application No.: US20080277396A1  Published: 13/Nov/2008

Title: DISPENSING DEVICE FOR A WASHING AND/OR RINSING AGENT, IN PARTICULAR FOR A DISH-WASHING MACHINE, AND PROVIDED WITH AN IMPROVED MECHANISM FOR MANUAL OPENING

Applicant/Assignee: ELBI INTERNATIONAL S.P.A

Application No.: 12/112424   Filing Date: 30/Apr/2008

Abstract:

The dispensing device for a washing and/or rinsing agent, in particular for a dishwashing machine, comprises: a stationary body designed to be integrally connected to the door of the dishwashing machine on the side directed during operation towards the washing chamber

a receptacle formed in the stationary body for receiving a quantity of a washing/rinsing agent and having a respective mouth

and a movable lid associated with the receptacle and displaceable in a manner constrained to the stationary body against the action of resilient return means from an open position into a closed position, where it opens and closes the mouth, respectively. The dispensing device also includes a manual opening mechanism for the movable lid, which comprises a retaining apparatus able to assume an activated configuration, in which it is designed to lock the movable lid in the closed position, and a deactivated configuration, in which it is able to free the movable lid, allowing it to pass from the closed position into the open position

and an operating member of the monostable type located on the side of the stationary body which during operation of the dishwashing machine is directed upwards and displaceable against the action of first resilient recall means from a stable extracted position into an unstable retracted position, in which positions the operating member arranges the associated retaining apparatus in the activated configuration and in the deactivated configuration, respectively.

Priority: IT2007TO00062U Applic. Date: 2007-05-09

Inventor: MARONE GIUSEPPE [IT]


Application No.: US20080277404A1  Published: 13/Nov/2008

Title: DRINKING APPARATUS AND METHOD

Applicant/Assignee:

Application No.: 12/115095   Filing Date: 05/May/2008

Abstract:

An apparatus for use in drinking liquid includes first and second drinking vessels. A connector extends between the drinking vessels. A passage may be provided in the connector. Two people can drink from the drinking apparatus at one time. When two people are drinking from the drinking apparatus, liquid flows between the passage in the connector and the first and second drinking vessels.

Priority: US20070927840P Applic. Date: 2007-05-07

Inventor: SKALA THEODORE P [US]


Application No.: US20080277814A1  Published: 13/Nov/2008

Title: Polymerizable compositions with acylgermanium compounds

Applicant/Assignee: IVOCLAR VIVADENT AG

Application No.: 11/902865   Filing Date: 26/Sep/2007

Abstract:

Composition with at least one polymerizable binder and at least one polymerization initiator, which contains at least one acylgermanium compound according to general Formula (I), in which R<0 >is a substituted or unsubstituted C1-18-alkyl radical or an acyl group

R<1 >and R<2 >are H, an acyl group or have one of the meanings given for R<3>

R<3 >is a branched or linear C1-18-alkyl radical which can be unsubstituted or substituted one or more times by -O-, -NH-, -NR-, -S- or interrupted by other groups, trimethylsilyl, hal-(CH3)2Si-[OSi(CH3)2]r<->, (CH3)3Si-[OSi(CH3)2]r-, -COOH, -COO-R<10>, -CO-NR<11>R<12>, -CO-vinyl, -CO-phenyl, phenyl-C1-4-alkyl, phenyl, naphthyl or biphenyl, C5-12 cycloalkyl, a 5 or 6-membered O, S or N-containing heterocyclic ring, halogen, OH, an aromatic C6-30 radical which can be substituted or unsubstituted and/or interrupted by O, S or -NR-, or a branched, cyclic or linear C1-20 alkyl, -alkenyl, -alkoxy or -alkenoxy radical

m is 1, 2 or 3

n is 0 or 1 and p is 0 or 1

wherein in each case two of the radicals R<0>, R<1>, R<2 >or R<3 >can be connected to each other accompanied by the formulation of a 5 to 8 member ring

and the use of acylegermanium compounds of Formula (I), for example, as initiator for radical polymerization.

Priority: EP20060121333 Applic. Date: 2006-09-27; EP20070112299 Applic. Date: 2007-07-11

Inventor: MOSZNER NORBERT [LI]; SALZ ULRICH [DE]; FISCHER URS KARL [CH]; LISKA ROBERT [AT]; GRUBER HEINRICH [AT]; GANSTER BEATE [AT]


Application No.: US20080279822A1  Published: 13/Nov/2008

Title: Crystalline Polymorphs of a CXC-Chemokine Receptor Ligand

Applicant/Assignee: SCHERING CORPORATION

Application No.: 12/174470   Filing Date: 16/Jul/2008

Abstract:

The present invention relates to four distinct crystalline polymorphs of a monohydrate of Compound A having the following chemical structure: Compound A. These four polymorphic forms, herein referred to as Forms I, II III and IV are active as a CXC-chemokine receptor ligands. The invention is further directed to formulations, methods of treatment, and processes of synthesis of these polymorphic forms.

Priority: US2005-045772 Applic. Date: 2005-01-28; US20040540487P Applic. Date: 2004-01-30

Inventor: HU MENGWEI [US]; YU YOUNONG [US]; DWYER MICHAEL [US]; TAVERAS ARTHUR [US]; KIM-MEADE AGNES [US]; YIN JIANGUO [US]; FU XIAOYONG [US]; MCALLISTER TIMOTHY [US]; ZHANG SHUYI [US]; KLOPFER KEVIN [US]


Application No.: US20080280251A1  Published: 13/Nov/2008

Title: Dent-Chew Brush

Applicant/Assignee:

Application No.: 11/701856   Filing Date: 01/Feb/2007

Abstract:

The Dent-Chew Brush is an oral appliance designed similarly to a mouth guard, in that it has two inverted channels in which the teeth are positioned when it is placed into the mouth. In its completed design it provides the user with the ability to brush all three exposed surfaces of the teeth of the upper and lower bite, the gingival margin, and the surface of the tongue. The completed process produces clean teeth and freshened breath that is comparable to a traditional brushing. The appliance will provide military personnel in the field the same level of oral hygiene as traditional brushing but without the need for water or a dentifrice. Additionally, the market includes anyone who desires to brush their teeth at their discretion using a completely self contained appliance. The Dent-Chew Brush is a single use disposable piece that is water soluble and bio-degradable.

Priority: US20060764119P Applic. Date: 2006-02-01

Inventor: GALLAGHER JOHN HENRY [US]


Application No.: US20080280296A1  Published: 13/Nov/2008

Title: METHOD FOR DETECTION OF FOOT-AND-MOUTH DISEASE VIRUS WITH CHROMATOGRAPHIC STRIP TEST

Applicant/Assignee:

Application No.: 11/956562   Filing Date: 14/Dec/2007

Abstract:

The present invention discloses a method for detection of foot-and-mouth disease virus with chromatographic strip test. Firstly, the nucleic acid sequence of FMDV NSPs is set up, the nucleic acid sequence is amplified by the reverse transcriptase polymerase chain reaction (RT-PCR) method, the recombinant vector is constructed and performed through a prokaryotic system to transform and express the recombinant protein, and the purified recombinant protein is mass produced. Design principles of the method are based on immunoassay and chromatographic analysis. The advantages are easy and simple to handle, no need of elaborate equipment, only one drop of body fluid is required to quickly complete the qualitative test in 10-20 minutes, and operating with a portable POCT (Point of care testing) instrument to complete the quantitative detection within 40-50 minutes.

Priority: TW20070116924 Applic. Date: 2007-05-11

Inventor: CHEN TSU-HAN [TW]; PAN CHU-HSIANG [TW]; JONG MING-HWA [TW]


Application No.: US20080280835A1  Published: 13/Nov/2008

Title: Novel Use of Peptide Compounds For Treating Muscle Pain

Applicant/Assignee:

Application No.: 12/063956   Filing Date: 18/Aug/2006

Abstract:

The present invention is directed to the use of a class of peptide compounds for treating non-inflammatory musculoskeletal pain or/and non-inflammatory osteoarthritic pain.

Priority: EP20050017977 Applic. Date: 2005-08-18; US20060811840P Applic. Date: 2006-06-08; US20060811859P Applic. Date: 2006-06-08; WO2006EP08171 Applic. Date: 2006-08-18

Inventor: BEYREUTHER BETTINA [DE]; STOHR THOMAS [DE]


Application No.: US20080280856A1  Published: 13/Nov/2008

Title: Fibroblast Activation Protein Inhibitor Compounds and Methods

Applicant/Assignee: GENENTECH, INC

Application No.: 12/133148   Filing Date: 04/Jun/2008

Abstract:

Amino terminus-blocked peptide boronate compounds of Formulas I and II are useful for inhibiting Fibroblast Activation Protein (FAP) and other proteases, and for treating disorders mediated by FAP. Methods of using the amino terminus blocked peptide boronate compounds, and stereoisomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

Priority: US2006-437182 Applic. Date: 2006-05-18; US20050730292P Applic. Date: 2005-10-25; US20050682970P Applic. Date: 2005-05-19

Inventor: COHEN FREDERICK [US]; FAIRBROTHER WAYNE J [US]; QUAN CLIFFORD [US]; SUTHERLIN DANIEL P [US]; WOLF BENI B [US]


Application No.: US20080280869A1  Published: 13/Nov/2008

Title: Pyrazole or Triazole Compounds and Their Use for the Manufacture of a Medicament for Treating Somatic Mutation-Related Diseases

Applicant/Assignee:

Application No.: 11/577177   Filing Date: 13/Oct/2005

Abstract:

The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.

Priority: US20040617670P Applic. Date: 2004-10-13; US20040617633P Applic. Date: 2004-10-13; US20040617634P Applic. Date: 2004-10-13; US20040617655P Applic. Date: 2004-10-13; US20040617653P Applic. Date: 2004-10-13; US20040624170P Applic. Date: 2004-11-03; WO2005US36761 Applic. Date: 2005-10-13

Inventor: ALMSTEAD NEIL [US]; KARP GARY M [US]; WILDE RICHARD [US]; WELCH ELLEN [US]; CAMPBELL JEFFREY A [US]; REN HONGYU [US]; CHEN GUANGMING [US]


Application No.: US20080280882A1  Published: 13/Nov/2008

Title: Novel Substituted Diazabicyclo Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee: NEUROSEARCH A/S

Application No.: 11/887622   Filing Date: 03/Apr/2006

Abstract:

This invention relates to novel substituted diazabicyclo derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000466 Applic. Date: 2005-04-04; US20050667669P Applic. Date: 2005-04-04; WO2006EP61261 Applic. Date: 2006-04-03

Inventor: PETERS DAN [SE]; NIELSEN ELSEBET OSTERGAARD [DK]; REDROBE JOHN PAUL [DK]


Application No.: US20080281347A1  Published: 13/Nov/2008

Title: Transoral Placement of Extragastric Devices

Applicant/Assignee:

Application No.: 12/109373   Filing Date: 09/Jun/2008

Abstract:

Methods and devices to externally create a restriction on the stomach are described. In some embodiments, the devices are contoured to fit the stomach and can be further anchored to the stomach. In further embodiments, the degree of deployment of the extragastric restriction device is controllable after implantation. In other embodiments, specialized wires, catheters, ports, and trocars specific for placement of extragastric restriction devices are presented. In still further embodiments, systems are described in which adjustability of the devices is provided along with sensing and actuating ability.

Priority: US2006-391126 Applic. Date: 2006-03-27; US2006-334105 Applic. Date: 2006-01-17; US2005-295281 Applic. Date: 2005-12-06; WO2005US33683 Applic. Date: 2005-09-19; US2005-148519 Applic. Date: 2005-06-09; US2005-153791 Applic. Date: 2005-06-15; US2005-125547 Applic. Date: 2005-05-10; WO2005US09322 Applic. Date: 2005-03-19; US2004-974248 Applic. Date: 2004-10-27; US20040556004P Applic. Date: 2004-03-23; US20040584219P Applic. Date: 2004-07-01; US20040603944P Applic. Date: 2004-08-23

Inventor: GERTNER MICHAEL [US]


Application No.: US20080283063A1  Published: 20/Nov/2008

Title: Universal dusk mask/filter for ATV and dirt bike riders, method of making and method of using

Applicant/Assignee:

Application No.: 12/151347   Filing Date: 06/May/2008

Abstract:

A face/dust mask constructed from differently-shaped filter media parts, each part having a different function, and each part interconnected so as to form a fitted air filter. Dual filters assist in eliminating from the intake air a substantial amount of the dust and debris encountered by riders of dirt bikes, manual bicycles, All-Terrain Vehicles, and other machines operated over unimproved, dusty terrain. By the nature of the materials and contours of the component parts, the mask fits comfortably and effectively for both adult and child users. The invention is highly resilient so as to adapt itself to the interior shape of a protective helmet or the mouthpiece section of a motorcycle helmet or similar safety helmet which is placed into position over the mask. The mask is of versatile design so as to enable a variety of embodiments with different filtering capabilities.

Priority: US20070928849P Applic. Date: 2007-05-14

Inventor: WILCOX TIMOTHY ANDREW [US]


Application No.: US20080283537A1  Published: 20/Nov/2008

Title: SPILL-RESISTANT CUPS WITH ACTIVE INGREDIENT DELIVERY SYSTEMS

Applicant/Assignee: EVERGREEN INNOVATION PARTNERS I, LP

Application No.: 12/111170   Filing Date: 28/Apr/2008

Abstract:

Spill-resistant cups for consuming beverages with delivery systems for simultaneously dispensing one or more agents which can reduce the rate of beverage-induced tooth decay and/or enamel erosion are disclosed herein. In one embodiment, the spill-resistant cup can include a hollow cup body defining a beverage holding chamber. The spill-resistant cup also includes a lid assembly with a drinking spout having one or more spaced-apart drinking holes. The drinking spout is configured to be engaged by a consumer's mouth. The lid assembly can positively engage the cup body to enclose the beverage holding chamber. The spill-resistant cup can also include an agent delivery system for controlled delivery of the active ingredient to the consumer's mouth. Further, the spill-resistant cup can include a flow control element configured to limit a flow rate of the beverage from the beverage holding chamber to the drinking holes disposed in the drinking spout.

Priority: US20070914662P Applic. Date: 2007-04-27

Inventor: SMITH DAVID [US]; SMITH BARBARA [US]; FUNK JOHN [US]


Application No.: US20080285302A1  Published: 20/Nov/2008

Title: DENTAL CURING LIGHT HAVING A SHORT WAVELENGTH LED AND A FLUORESCING LENS FOR CONVERTING SHORT WAVELENGTH LIGHT TO CURING WAVELENGTHS AND RELATED METHOD

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 12/145115   Filing Date: 24/Jun/2008

Abstract:

A dental curing light includes a body, one or more LEDs configured to emit a first spectrum of light having a relatively short first peak wavelength (e.g., UV) disposed on the body, and a fluorescing lens that converts at least a portion of the first spectrum of light into a second spectrum of light having a second peak wavelength that is longer than the first peak wavelength. The second spectrum of light is selected so as to match the curing spectrum of a desired light-curable dental composition. In a preferred embodiment, the body comprises an elongate wand having a proximal end and distal end. The LEDs may be disposed at or near the distal end of the elongate wand.

Priority: US2005-184433 Applic. Date: 2005-07-19; US2003-423275 Applic. Date: 2003-04-25; US2003-411913 Applic. Date: 2003-04-11

Inventor: SCOTT ROBERT R [US]; JESSOP DEE [US]; FISCHER DAN E [US]; NOSOV VASILIY [RU]


Application No.: US20080286210A1  Published: 20/Nov/2008

Title: NOVEL ANTIMICROBIAL PEPTIDES

Applicant/Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA C3 JIAN, INC THE REGENTS OF THE UNIVERSITY OF CALIFORNIA C3 JIAN, INC

Application No.: 12/014634   Filing Date: 15/Jan/2008

Abstract:

This invention provides novel antimicrobial peptides that are effective to inhibit growth and/or proliferation of various gram positive bacteria. In particular, the peptides are effective against Streptococcus mutans a common oral pathogen and the causative agent of dental caries.

Priority: US20070880783P Applic. Date: 2007-01-16

Inventor: HE JIAN [US]; ECKERT RANDAL H [US]; QI FENGXIA [US]; ANDERSON MAXWELL H [US]; SHI WENYUAN [US]


Application No.: US20080286211A1  Published: 20/Nov/2008

Title: Using mucin glycoproteins in combination with therapeutic agents to treat epithelial lesions and disorders of impaired mucin function

Applicant/Assignee:

Application No.: 12/150082   Filing Date: 24/Apr/2008

Abstract:

The present invention features methods of treating a patient having an epithelial lesion or disorder of impaired mucin function. The present invention further features methods of treating pain associated with epithelial lesions and disorders of impaired mucin function. Epithelial lesions and disorders of impaired mucin function can be treated using a pharmaceutical composition containing mucin glycoproteins in combination with therapeutic agents, e.g., trefoil polypeptides.

Priority: US20070914692P Applic. Date: 2007-04-27

Inventor: BARKER NICHOLAS P [US]


Application No.: US20080286215A1  Published: 20/Nov/2008

Title: Method of Preventing Oral Staining

Applicant/Assignee:

Application No.: 12/091617   Filing Date: 22/Nov/2006

Abstract:

A cosmetic method of preventing or decreasing oral staining, comprising the step of exposing the oral cavity to a morpholino compound having the general formula (I) wherein R1 is a straight or branched alkyl group containing 8 to 16 carbon atoms at the 2- or 3-position of the morpholino ring, and R2 is a straight or branched alkyl group containing 2 to 10 carbon atoms, substituted with a hydroxy group except in the alpha-position, or a pharmaceutically acceptable salt thereof.

Priority: GB20050023743 Applic. Date: 2005-11-22; WO2006GB04357 Applic. Date: 2006-11-22

Inventor: ATTSTROM ROLF VALTER [CH]


Application No.: US20080286216A1  Published: 20/Nov/2008

Title: Surface Active Calcium Phosphates

Applicant/Assignee:

Application No.: 12/095044   Filing Date: 15/Dec/2006

Abstract:

A nitrogen complex of an inorganic phosphate comprising the anionic sub-structure (I)

whereby a nitrogen atom (N) of a complexing agent is complexed to an oxygen atom (O) of the inorganic phosphate

wherein the nitrogen atom is selected from the group consisting of a nitrogen atom of an amine group or a nitrogen atom of a N-heteroaromatic ring

and wherein A and A' are each independently selected from the group of constituents consisting of a hydroxyl group (-OH), an oxide group (-O<->), the group -OR where R is alkyl or substituted alkyl

an oxygen to which a nitrogen is complexed (-0<-N) wherein the nitrogen atom is selected from the group consisting of a nitrogen atom of an amine group or a nitrogen atom of a N-heteroaromatic ring

and a phosphate of the form (i)

wherein each of A'' and A''' are selected independently from the same group of substituents as A and A'

wherein at least one of A, A', A'' and A''' is an oxide (-O<->) with the proviso that when A' and A''' are not present then at least one of A and A' is an oxide (-O<->).

Priority: US20050751335P Applic. Date: 2005-12-16; WO2006AU01914 Applic. Date: 2006-12-15

Inventor: KANNAR DAVID [AU]; VERDICCHIO ROBERT [US]


Application No.: US20080286318A1  Published: 20/Nov/2008

Title: Oral Care Compositions

Applicant/Assignee: AMCOL INTERNATIONAL CORPORATION

Application No.: 11/815672   Filing Date: 24/Feb/2006

Abstract:

An oral care composition containing polymeric microparticles highly loaded with an oral care compound is disclosed.

Priority: US20050656276P Applic. Date: 2005-02-25; WO2006US06611 Applic. Date: 2006-02-24

Inventor: SPINDLER RALPH [US]; URBANEC STEPHEN J [US]; LARIONOVA NATALIYA V [US]


Application No.: US20080286328A1  Published: 20/Nov/2008

Title: Implant and Production Method for Said Implant

Applicant/Assignee: NEXILIS AG

Application No.: 12/091902   Filing Date: 17/Oct/2006

Abstract:

The invention relates to an implant, e.g. a stent, bone replacement material, a prosthesis, a scaffold or similar, which comprises a coating at least in those surface areas that come into contact with hard and/or soft tissue when implanted. To ensure that the active ingredient contained in the coating (bisphosphonate) is released into the surrounding tissue or can act in the latter in a controlled manner at the correct speed, the coating is characterised in that it contains bisphosphonate, the respective pharmaceutically compatible salts or esters of the latter, in addition to at least one amphiphilic component, selected from the group containing branched or linear, substituted or unsubstituted, saturated or partially unsaturated C10-C30 alkyl-, alkenyl, alkylaryl-, aryl-, cycloalkyl-, alkylcycloalkyl-, alkylcycloaryl-carboxylates, -phosphates or -sulfates or mixtures thereof and/or a water-soluble ionic polymer component. The invention also relates to a method for producing an implant of this type and to a specific composition, which can be used to produce a coating of this type.

Priority: CH20050001724 Applic. Date: 2005-10-27; WO2006CH00576 Applic. Date: 2006-10-17

Inventor: SCHLOTTIG FALKO [CH]; SCHNABELRAUCH MATTHIAS [DE]; KAUTZ ARMIN REX [DE]


Application No.: US20080286367A1  Published: 20/Nov/2008

Title: Compositions containing benefit agent composites pre-emulsified using colloidal cationic particles

Applicant/Assignee: AMCOL INTERNATIONAL CORPORATION

Application No.: 12/152364   Filing Date: 14/May/2008

Abstract:

A cleansing or a surface-conditioning composition comprising a mixture of (i) and (ii) in water: i) a surfactant selected from the group consisting of anionic, non-ionic, zwitterionic, cationic, and mixtures thereof

and ii) a hydrophobic benefit agent in a particulate form having a mean particle size in the range of 1-1,000 micron, and a specific gravity of >=1, not encapsulated within a film or a capsule-like enclosure, the particulate hydrophobic benefit agent comprising: a) a physically-modified form of the hydrophobic benefit agent

and b) a deposition-aid material bonded to the surface of the physically-modified benefit agent material, wherein the bonding between the two said materials is achieved prior to addition to i), wherein said deposition-aid material is not a surfactant having a weight average molecular weight of less than 5,000 Dalton.

Priority: US20070917832P Applic. Date: 2007-05-14

Inventor: SENGUPTA ASHOKE K [US]; LIN ILONA [US]; ST ONGE JASON [US]; HUGHES MELANIE J [GB]


Application No.: US20080287300A1  Published: 20/Nov/2008

Title: CO-PRECIPITATED CARRAGEENAN/XANTHAN GUM COMPOSITIONS AND PROCESSES FOR THEIR PREPARATION

Applicant/Assignee: FMC CORPORATION

Application No.: 12/108607   Filing Date: 24/Apr/2008

Abstract:

Co-precipitated carrageenan/xanthan gum compositions and a process for preparation are provided. The compositions are simple to prepare and provide functional performance in a broad range of food, specialty and industrial applications.

Priority: US20070926008P Applic. Date: 2007-04-24; US20070926219P Applic. Date: 2007-04-25; US20070940881P Applic. Date: 2007-05-30; US20080040546P Applic. Date: 2008-03-28

Inventor: KOPESKY ROBERT [US]; BRAWN W PRESTON [US]; SEWALL CHIRSTPHER J [US]; DEMARCO JOHN [US]; LAMKEY JAMES [US]


Application No.: US20080287392A1  Published: 20/Nov/2008

Title: Wound-Healing Pharmaceutical Compositions in the Form of a Cream Based on Amino Acids and Sodium Hyaluronate

Applicant/Assignee: SOLARTIUM LLC

Application No.: 12/091462   Filing Date: 16/Oct/2006

Abstract:

This invention relates to wound-healing pharmaceutical or cosmetic (anti-skin aging) compositions in the form of a cream based on amino acids and sodium hyaluronate.

Priority: IT2005MI02035 Applic. Date: 2005-10-26; WO2006EP09966 Applic. Date: 2006-10-16

Inventor: CONTI FRANCO [IT]


Application No.: US20080287398A1  Published: 20/Nov/2008

Title: COLD MENTHOL RECEPTOR-1 ANTAGONISTS

Applicant/Assignee:

Application No.: 12/114325   Filing Date: 02/May/2008

Abstract:

The invention is directed to TRPM8 antagonists of Formula (I). More specifically, the present invention relates to certain novel compounds, methods for preparing compounds, compositions, intermediates and derivatives thereof and methods for treating TRPM8-mediated disorders. Pharmaceutical and veterinary compositions and methods of treating pain and various other disease states or conditions using compounds of the invention are also described.

Priority: US20070915527P Applic. Date: 2007-05-02

Inventor: COLBURN RAYMOND W [US]; DAX SCOTT L [US]; FLORES CHRISTOPHER [US]; MATTHEWS JAY [US]


Application No.: US20080287415A1  Published: 20/Nov/2008

Title: Bicycloheteroaryl compounds as P2X7 modulators and uses thereof

Applicant/Assignee:

Application No.: 12/075111   Filing Date: 07/Mar/2008

Abstract:

Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

Priority: US20070906049P Applic. Date: 2007-03-09; US20070918261P Applic. Date: 2007-03-15; US20070918123P Applic. Date: 2007-03-15; US20070918260P Applic. Date: 2007-03-15; US20070918086P Applic. Date: 2007-03-15; US20070008370P Applic. Date: 2007-12-20; US20070008385P Applic. Date: 2007-12-20; US20070008386P Applic. Date: 2007-12-20; US20080010672P Applic. Date: 2008-01-10

Inventor: KELLY MICHAEL G [US]; KINCAID JOHN [US]; FANG YUNFENG [US]; CAO YEYU [US]; KAUB CARL [US]; GOWLUGARI SUMITHRA [US]; WANG ZHAN [US]


Application No.: US20080287443A1  Published: 20/Nov/2008

Title: Treatment of Subgingival Pocket Infections

Applicant/Assignee:

Application No.: 12/091784   Filing Date: 22/Nov/2006

Abstract:

Use of a morpholino compound having the general formula (I) wherein R1 is a straight or branched alkyl group containing (8) to (16) carbon atoms at the 2- or 3-position of the morpholino ring, and R2 is a straight or branched alkyl group containing (2) to (10) carbon atoms, substituted with a hydroxy group except in the alpha-position, or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the treatment of an infected sub-gingival pocket.

Priority: GB20050023745 Applic. Date: 2005-11-22; GB20060000324 Applic. Date: 2006-01-09; WO2006GB04348 Applic. Date: 2006-11-22

Inventor: PERSSON GOSTA RUTGER [CH]


Application No.: US20080287487A1  Published: 20/Nov/2008

Title: Muscarinic Acetylcholine Receptor Antagonists

Applicant/Assignee:

Application No.: 11/570981   Filing Date: 30/Jun/2005

Abstract:

Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.

Priority: US20040584011P Applic. Date: 2004-06-30; WO2005US23743 Applic. Date: 2005-06-30

Inventor: COOPER ANTHONY WILLIAM JAMES [GB]; LAINE DRAMANE I [US]; PALOVICH MICHAEL R [US]; THOMAS SONIA M [US]


Application No.: US20080287537A1  Published: 20/Nov/2008

Title: Composition, Particularly a Cosmetic Composition, Comprising ((Dialkylamino)Alkoxy) Ethanol Ester

Applicant/Assignee: L'OREAL

Application No.: 11/579593   Filing Date: 18/Apr/2005

Abstract:

The present invention relates to a process for the cosmetic treatment of wrinkled skin, comprising the topical application to the said skin of a composition comprising, in a physiologically acceptable medium, at least one ester of ((dialkylamino)alkoxy)ethanol of formula (I): It also relates to novel compounds belonging to the formula (I) and corresponding to the formulae (II) and (III): and to the cosmetic compositions comprising them.

Priority: FR20040004914 Applic. Date: 2004-05-06; US20040574594P Applic. Date: 2004-05-27; WO2005FR00927 Applic. Date: 2005-04-18

Inventor: DALKO MARIA [FR]


Application No.: US20080287562A1  Published: 20/Nov/2008

Title: Stable cationically crosslinkable/polymerizable dental composition with a high filler content

Applicant/Assignee: RHODIA CHIMIE BLUESTAR SILICONES FRANCE

Application No.: 12/149536   Filing Date: 02/May/2008

Abstract:

Stable and substantially filled cationic dental compositions are described which include: (1) at least one cationically reactive compound (A)

(2) at least one dental filler (B)

(3) optionally, at least one dispersant (C) composed of at least one organic polymer or copolymer

(4) at least one cationic photoinitiator (D)

and (5) optionally, at least one photosensitizer (E). The dental filler (B) is treated with at least one organosilicon coupling agent (F), and at least one compound (G). The organosilicon coupling agent (F) has at least one reactive function (rfA) directly linked to a silicon atom forming after activation of a chemical bond with the dental filler, and at least one reactive function (rfB) not directly linked to a silicon atom, forming after activation, a chemical bond with a reactive function (rfC) of the compound (G).

Priority: FR20040005177 Applic. Date: 2004-05-13; FR20040007209 Applic. Date: 2004-06-30; US2005-126273 Applic. Date: 2005-05-11; US20040599064P Applic. Date: 2004-08-06

Inventor: FRANCES JEAN-MARC [FR]; DERUELLE MARTIAL [FR]; GIRAUD YVES [FR]


Application No.: US20080287846A1  Published: 20/Nov/2008

Title: Oral Cleaning Device with Internal Toothpaste

Applicant/Assignee:

Application No.: 12/094402   Filing Date: 19/Sep/2006

Abstract:

The present invention relates to an oral cleaning device with comprises an opening/closing lever integrally mounted to an upper end portion of a hydrant for opening and closing the hydrant so as to discharge water supplied from the hydrant

and an oral cleaning unit detachably mounted to the hydrant for allowing toothpaste T contained in the oral cleaning device to be diluted with the water supplied from the hydrant in response to the opening/closing operation of the opening/closing lever, and then allowing the inside of a user's mouth to be cleansed by injecting the water diluted with the toothpaste T. Accordingly, a user can feel refreshment only by mouth gargling with the oral cleaning device without tooth brushing, thereby allowing the refreshment to be kept.

Priority: KR20050033849U Applic. Date: 2005-11-30; WO2006KR03719 Applic. Date: 2006-09-19

Inventor: SONG KONG SUK [KR]


Application No.: US20080289512A1  Published: 27/Nov/2008

Title: Food product toaster

Applicant/Assignee: PRINCE CASTLE INC

Application No.: 11/805671   Filing Date: 24/May/2007

Abstract:

A toaster for bread-type food products includes a housing defining at least one toasting cavity having an upper mouth for depositing the food products into the cavity and a lower opening from which toasted food products exit the cavity. A perforate rack is provided beneath the lower opening and onto which the toasted food products are deposited as they exit the cavity. The rack is perforated to significantly reduce the surface area of the rack which might otherwise stick to the toasted food products. An imperforate plate is juxtaposed behind the perforate rack to prevent crumbs from the toasted food products from falling into the bottom of the toaster. The plate is spaced from the rack a sufficient distance to prevent any portions of the toasted food products from projecting through the perforate rack and touching the plate and sticking thereto.

As disclosed herein, the perforate rack is provided as a wire form structure. At least a portion of the rack is angled to form a ramp down which the toasted food products move toward the front of the toaster. Preferably, the imperforate plate comprises a metal sheet.

Priority:

Inventor: LONG ROBERT C [US]; MACIEJEWSKI MICHAEL M [US]


Application No.: US20080292565A1  Published: 27/Nov/2008

Title: TOOTH FLUORIDATING AND REMINERALIZING COMPOSITIONS AND METHODS, BASED ON NANOAGGREGATE FORMATION

Applicant/Assignee: ADA FOUNDATION

Application No.: 12/126426   Filing Date: 23/May/2008

Abstract:

Compositions and methods for forming, in an aqueous environment, a nanoaggregate of calcium fluoride and amorphous calcium phosphate-containing compound, such as amorphous calcium phosphate fluoride or amorphous calcium carbonate phosphate fluoride are described. The nanoaggregate (or nanocomposite) can release calcium, phosphate, and fluoride, and ultimately convert to the tooth mineral, fluorapatite. One method for forming such a nanoaggregate involves applying a non-aqueous (e.g., varnish-based) composition (e.g., a suspension), containing solid particles of water soluble salts of calcium, phosphate, and fluoride, to the aqueous environment of the mouth. This results in rapid solubilization of the salts, precipitation of the nanoaggregate, and tooth remineralization. Tooth fluoridation and remineralization may also be carried out by applying to the tooth a non-aqueous carrier containing the nanoaggregate. Whitening agents can also be added to these compositions and methods.

Priority: US20070939928P Applic. Date: 2007-05-24

Inventor: TUNG MING S [US]


Application No.: US20080292566A1  Published: 27/Nov/2008

Title: ORAL COMPOSITION CONTAINING MORIN

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/185585   Filing Date: 04/Aug/2008

Abstract:

The present invention relates to an oral composition useful to reduce inflammatory processes. More specifically, the invention relates to a composition consisting essentially of an anti-oxidative effective amount of morin and a water-humectant phase, and to a composition comprising an anti-oxidative effective amount of morin, one or more anti-bacterial agents and a water-humectant phase. In an embodiment, the composition is used in a method of preventing or treating inflammatory dental diseases such as gingivitis and periodontitis.

Priority: US2005-256784 Applic. Date: 2005-10-24

Inventor: CAMERON RYAN BRADLEY [US]; SUBRAMANYAM RAVI [US]; TRIVEDI HARSH [US]; WORRELL CORTNEY [US]


Application No.: US20080292592A1  Published: 27/Nov/2008

Title: Oncolytic Adenovirus Armed with Therapeutic Genes

Applicant/Assignee:

Application No.: 11/568499   Filing Date: 02/May/2005

Abstract:

The present invention involves compositions and methods for treating preventing cancer using compositions including replication competent adenovirus. The application competent adenovirus may or may not encode a therapeutic polynucleotide.

Priority: US20040566674P Applic. Date: 2004-04-30; WO2005US15157 Applic. Date: 2005-05-02

Inventor: CHADA SUNIL [US]; WOLD WILLIAM [US]; ZUMSTEIN LOU [US]


Application No.: US20080292669A1  Published: 27/Nov/2008

Title: Foamed Substrate and Method for Making Same

Applicant/Assignee: SMITHKLNE BEECHAM CORPORTION

Application No.: 12/094650   Filing Date: 20/Nov/2006

Abstract:

The present invention provides a foamed and/or aerated substrate for transmucosal and/or transdermal applications. The foamed and/or aerated substrate may be in the form of a film, sheet, strip or wafer. The foamed and/or aerated substrate is suitable for use in applications such as, for example, adhesive denture liners, tooth whitening, and smoking control/cessation. The foamed and/or aerated substrate is polymeric in nature and comprises one or more polymers and one or more foaming agents. Additionally, the foamed and/or aerated substrate may include, but not limited to, one or more plasticizers, hydrophobic barrier agents, tooth whitening agents, antioxidants, preservatives, super-disintegrants or absorbents, flavorants, deodorants, breath freshening agents, colorants, surfactants, film modifiers, cross-linking agents, antimicrobial agents, control release agents, other therapeutic agents, or any combinations thereof.

Priority: US20050738923P Applic. Date: 2005-11-22; WO2006US61090 Applic. Date: 2006-11-20

Inventor: DENG FANG [US]; LECH STANLEY J [US]


Application No.: US20080292687A1  Published: 27/Nov/2008

Title: Methods of Treating Cancer and Other Conditions or Disease States Using Lfmau and Ldt

Applicant/Assignee: YALE UNIVERSITY

Application No.: 11/921194   Filing Date: 05/Jun/2006

Abstract:

The present invention relates to the use of the compound according to formula (I), below for the treatment of tumors, cancer and hyperproliferative diseases, among other conditions or disease states: Where X is H or F

R1 and R2 are independently H, an acyl group, a C1-C20 alkyl or ether group, a phosphate, diphosphate, triphosphate or a phosphodiester group, a (A) or (B) group

Where Nu is a radical of a biologically active compound such as an anticancer, antiviral or antihyperproliferative compound such that an amino group or hydroxyl group from said biologically active agent forms a phosphate, phosphoramidate, carbonate or urethane group with the adjacent moiety

each R8 is independently H, or a C1-C20 alkyl or ether group, preferably a C1-C12 alkyl group

k is 0-12, preferably, 0-2

and pharmaceutically acceptable salts thereof.

Priority: US20050741728P Applic. Date: 2005-12-02; US20050688159P Applic. Date: 2005-06-07; WO2006US21742 Applic. Date: 2006-06-05

Inventor: CHENG YUNG CHI [US]


Application No.: US20080292689A1  Published: 27/Nov/2008

Title: METHOD FOR INHIBITING FREE RADICALS

Applicant/Assignee:

Application No.: 12/187959   Filing Date: 07/Aug/2008

Abstract:

A method for inhibiting free radical is provided. The method includes administering to a subject an effective amount of an herbal composition including Polygonum cuspidatum and/or Viola yedoensis. The herbal composition is suitable for mammalian subjects. The Polygonum cuspidatum is selected from fresh Polygonum cuspidatum herbage, and the Viola yedoensis is selected from fresh Viola yedoensis herbage.

Priority: TW20050147657 Applic. Date: 2005-12-30; US2006-432372 Applic. Date: 2006-05-12

Inventor: ROW LIE-CHING [TW]; CHEN LIEN TAI [TW]


Application No.: US20080292779A1  Published: 27/Nov/2008

Title: COATING OF IMPLANTS WITH HYALURONIC ACID SOLUTION

Applicant/Assignee:

Application No.: 12/110641   Filing Date: 28/Apr/2008

Abstract:

A method for fabricating and/or coating an implant or other structure to be inserted into bone or osseous tissue, including dental implants, is described in which the surface of the implant is treated with a hyaluronic acid solution to form a thin film conformal coating of the hyaluronic solution over the surface of the implant. The surface of the implant may be roughened and cleaned prior to treating the surface with the hyaluronic solution. After the coating is formed, the implant may be sterilized.

Priority: US20070939461P Applic. Date: 2007-05-22

Inventor: MERCURI GREGORY M [US]; HALL JAMES G [US]


Application No.: US20080293009A1  Published: 27/Nov/2008

Title: Ultrasonic dental cleaner

Applicant/Assignee:

Application No.: 12/149971   Filing Date: 12/May/2008

Abstract:

An ultrasonic dental cleaning device for ultrasonically removing deposits from the surface of teeth using a low voltage design. The device having a handle with an ultrasonic driving system for transmitting ultrasonic energy containing a mixed iron oxide rod, a coil around the mixed iron oxide rod, a processor connected to the coil configured and adapted to output ultrasonic electrical energy, and at least two leads connected to a magnet on either end of the rod and coil. A cleaning tip is operably coupled to the handle and configured to be driven to oscillate by the ultrasonic driving system. A power supply configured and adapted to provide electric power to the ultrasonic driving system with a cord.

Priority: US20070928599P Applic. Date: 2007-05-10

Inventor: WINSTON RONALD H [US]


Application No.: US20080293015A1  Published: 27/Nov/2008

Title: Adhesive Liner

Applicant/Assignee: SMITHKLINE BEECHAM CORPORATION

Application No.: 12/094652   Filing Date: 20/Nov/2006

Abstract:

The present invention provides a denture adhesive liner in the form of an extruded film or sheet, comprising a denture adhesive effective amount of alginate

thermoplastic polymer

and plasticizer, wherein said composition is extrudable into a film that is capable of adhering to a wet mucous surface. The present invention also provides a method for preparing a denture adhesive liner comprising the steps of: preparing a composition of a denture adhesive effective amount of alginate

thermoplastic polymer

and plasticizer

and forming a denture adhesive liner from the composition.

Priority: US20050738904P Applic. Date: 2005-11-22; WO2006US61089 Applic. Date: 2006-11-20

Inventor: WONG EDDIE [US]; WILENSKY STUART B [US]; BIDDESCOMB JOHN R [US]; LECH STANLEY J [US]


Application No.: US20080293018A1  Published: 27/Nov/2008

Title: Malleable Symmetric Dental Crowns

Applicant/Assignee:

Application No.: 11/912915   Filing Date: 27/Apr/2006

Abstract:

Preformed malleable dental crowns with a side-generic external shape with a plane of symmetry in the facial-lingual direction and/or a plane of symmetry in the mesial-distal direction. The preformed dental crowns also include a hardenable composition that has sufficient malleability such that the side-generic external shape can be formed into, e.g., a left-side specific or right-side specific adjusted external shape. Methods of the invention may include fitting the dental crowns by adjusting or forming them to provide side-specific features, followed by hardening of the hardenable composition.

Priority: US20050676433P Applic. Date: 2005-04-29; WO2006US16197 Applic. Date: 2006-04-27

Inventor: KARIM NAIMUL [US]; BIEGLER ROBERT M [US]; COLBURN DAVID J [US]; JACOBS DWIGHT W [US]; KECK STEVEN C [US]


Application No.: US20080293737A1  Published: 27/Nov/2008

Title: ION CHANNEL MODULATORS AND METHODS OF USE

Applicant/Assignee:

Application No.: 12/124303   Filing Date: 21/May/2008

Abstract:

In general, the invention relates to compounds useful as ion channel modulators. It has now been found that compounds of this invention, and pharmaceutically acceptable compositions thereof, are useful as inhibitors of voltage-gated sodium channels.

Priority: US20070931722P Applic. Date: 2007-05-25

Inventor: MARTINBOROUGH ESTHER [US]; NEUBERT TIM [US]; WHITNEY TARA [US]; LEHSTEN DANIELLE [US]; HAMPTON TARA [US]; ZIMMERMAN NICOLE [US]; TERMIN ANDREAS P [US]


Application No.: US20080293846A1  Published: 27/Nov/2008

Title: Dental Compositions with Surface-Treated Filler for Shelf Stability

Applicant/Assignee:

Application No.: 12/159237   Filing Date: 28/Dec/2006

Abstract:

The invention features dental compositions containing a basic filler that has been surface-treated with a strong acid to increase the shelf life of the composition.

Priority: US20050754985P Applic. Date: 2005-12-29; WO2006US49463 Applic. Date: 2006-12-28

Inventor: CRAIG BRADLEY D [US]; SHUKLA BRIAN A [US]


Application No.: US20080294067A1  Published: 27/Nov/2008

Title: Brush, Such as for Cleaning or Sampling Body Tissue

Applicant/Assignee: MDZ BEHEER B.V

Application No.: 12/096868   Filing Date: 14/Aug/2008

Abstract:

The present invention relates to a brush (1) for cleaning or sampling body tissue. The brush (1) comprises a support (2) that is provided with at least one row (3) of brush hairs (5) as well as one second row (4) of brush hairs (16). The first and second rows are mutually parallel and are situated next to one another. Each brush hair (5,6) has a proximal end (7) facing the support (2) and a distal end (9) facing away from the support (2). The first row (3) of brush hairs (5) comprises a strip (30) that extends in the longitudinal direction of the first row (3) and a longitudinal side (32) of which is fixed to the support (2). The proximal ends (7) of the brush hairs (5) in the first row (3) are fixed to the other longitudinal side (34) of the strip (30).

Priority: WO2005NL50092 Applic. Date: 2005-12-22

Inventor: ZWART MEINDERT DURK [NL]


Application No.: US20080295406A1  Published: 04/Dec/2008

Title: Kit and method for making a shutter

Applicant/Assignee:

Application No.: 11/807516   Filing Date: 29/May/2007

Abstract:

A kit containing components which can be assembled into a shutter panel includes a header, a footer, a plurality of brackets, a first stile, a second stile, a plurality of louvers. One embodiment also contains a jig to align the bracket with the header or footer for attachment. Each bracket is sized and configured to be connected to an end of the header or footer. The stiles each have a longitudinal channel which enables the stiles to be fitted over at least one of the brackets. The jig has a mouth sized to receive an end of the footer or header and a cavity adjacent the mouth such that a user of the jig can place one end of a bracket in the cavity and the other end of the header or footer in the mouth. The kit may be packaged in two packs. One pack contains a header, a footer and a plurality of brackets. The second pack contains mounting frame pieces, at least one first stile, at least one second stile, a plurality of louvers, louver strips, a tilt rod, screws and other hardware which can be assembled into a shutter panel having the desired dimensions. The header, footer, stiles and brackets are provided to a retailer in standard sizes. The retailer may then trim these components as required to create a shutter having the desired dimensions.

Priority:

Inventor: KOLLMAN MICHAEL [US]; SCHULTZ NICHOLAS J [US]


Application No.: US20080295476A1  Published: 04/Dec/2008

Title: GRAIN REAPER

Applicant/Assignee:

Application No.: 11/870888   Filing Date: 11/Oct/2007

Abstract:

The present invention relates to a reaper for grains, specially for the bean grains. More specifically, the present invention refers to technical and functional improvements specially developed and introduced which configures a bean reaper that is classified as a trailer to carry out two different operations, the first one of which is gathering various plants, such as bean plants, peanuts and other grains, plants which are previously plucked and aligned, whereas the second function of which is to perform a whole cleaning process by separating the grains (seeds) from the remaining unwanted parts.

Priority:

Inventor: BERTINO LUIZ HENRIQUE [BR]


Application No.: US20080295665A1  Published: 04/Dec/2008

Title: STEEL STRIP SHEARS WITH A HAMMERING DEVICE

Applicant/Assignee:

Application No.: 11/755853   Filing Date: 31/May/2007

Abstract:

A steel strip shears with a hammering device consists of a shearing device and a hammering device, which are pivotally connected at a preset location of their front portions, and respectively connected with a commanding handle and a positioning rod at their ends. The hammering device is installed at the rear portion of the positioning rod, able to move back and forth along the positioning rod to strike the rear surface of the positioning rod, so as to quickly squeeze a second blade connected in front of the positioning rod into under a steel strip tied around a packing box, getting ready for shearing.

Priority:

Inventor: YU CHEN HSIU-MAN [TW]


Application No.: US20080295850A1  Published: 04/Dec/2008

Title: INTEROCCLUSAL APPLIANCE AND METHOD

Applicant/Assignee: HAYLOFT ENTERPRISES, INC

Application No.: 11/757490   Filing Date: 04/Jun/2007

Abstract:

An interocclusal appliance is formed from a single polymer material composition as one unitary piece or from multiple polymer material compositions as a two-piece preform. The two-piece preform includes a base material and an impression material that has a softening point lower than the base material. Teeth are received into the heat-softened impression material, so as to contour the impression material. A portion of the impression material also may contour to a portion of the user's palate. In certain embodiments, substantially no polymeric material contacts the front surfaces of the front teeth, leading to greater comfort and better air flow between front teeth. In still another embodiment, the appliance fits over front teeth only and no polymeric material contacts the maxillary molars.

Priority:

Inventor: LESNIAK FRANK [US]


Application No.: US20080299053A1  Published: 04/Dec/2008

Title: ENHANCED DELIVERY OF CERTAIN FRAGRANCE COMPONENTS FROM PERSONAL CARE COMPOSITIONS

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER CONOPCO, INC

Application No.: 11/755007   Filing Date: 30/May/2007

Abstract:

A personal care composition is provided having a fragrance which incorporates limonene, gamma terpinene, ethylene brassylate or combinations thereof in conjunction with a quaternary ammonium salt. The salt has a structure AB, wherein A is a cationic charge component, B is an anionic charge component, and A has one quaternized nitrogen atom, at least two hydroxyl groups and a molecular weight no higher than about 250. The quaternary ammonium salt functions as a scent boosting agent to enhance volatilization of the fragrance components when the personal care composition is first applied to skin or hair of the human body.

Priority:

Inventor: YANG LIN [US]; CHANDAR PREM [US]


Application No.: US20080299054A1  Published: 04/Dec/2008

Title: PERSONAL CARE COMPOSITIONS WITH ENHANCED FRAGRANCE DELIVERY

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER

Application No.: 11/755009   Filing Date: 30/May/2007

Abstract:

A personal care product is provided which includes a fragrance, a substituted urea and a quaternary ammonium salt. The substituted urea and quaternary ammonium salt operate together as a scent boosting system to enhance volatilization of fragrance components upon the personal care composition being first applied to human skin or hair.

Priority:

Inventor: CHANDAR PREM [US]; YANG LIN [US]


Application No.: US20080299089A1  Published: 04/Dec/2008

Title: ENDOGENEOUS REPAIR FACTOR PRODUCTION PROMOTERS

Applicant/Assignee: ONO PHARMACEUTICAL CO., LTD

Application No.: 12/034614   Filing Date: 20/Feb/2008

Abstract:

It relates to an endogenous repair factor production accelerator which comprises one or at least two selected from prostaglandin (PG) 12 agonist, EP2 agonist and EP4 agonist. Since prostaglandin (PG) 12 agonist, EP2 agonist or EP4 agonist has various endogenous repair factor production accelerating action, angiogenesis acceleration action and stem cell differentiation induction action, it is useful as preventive and/or therapeutic agents for ischemic organ diseases (e.g., arteriosclerosis obliterans, Buerger disease, Raynaud disease, myocardial infarction, angina pectoris, diabetic neuropathy, spinal canal stenosis, cerebrovascular accidents, cerebral infarction, pulmonary hypertension, bone fracture, Alzheimer disease, etc.) and various cell and organ diseases.

Priority: JP20020298079 Applic. Date: 2002-10-10; JP20020318830 Applic. Date: 2002-10-31; JP20030117604 Applic. Date: 2003-04-22; US2005-530685 Applic. Date: 2005-04-08; WO2003JP12981 Applic. Date: 2003-10-09

Inventor: SAKAI YOSHIKI [JP]; NISHIURA AKIO [JP]; OGATA TEPPEI [JP]


Application No.: US20080299191A1  Published: 04/Dec/2008

Title: Fine-Particle Crosslinked Polyvinylpyrrolidone as Tablet Disintegrant

Applicant/Assignee: BASF SE

Application No.: 12/094516   Filing Date: 11/Dec/2006

Abstract:

Use of crosslinked polyvinylpyrrolidone with an average particle size of 5-60 mum and a hydration capacity of greater than 7 g/g as tablet disintegrant

Priority: EP20050112607 Applic. Date: 2005-12-21; EP20050112963 Applic. Date: 2005-12-23; WO2006EP69514 Applic. Date: 2006-12-11

Inventor: KOLTER KARL [DE]; FUSSNEGGER BERNHARD [DE]; KERBER MICHAEL [DE]; ARMBRUSTER HARALD [DE]; FOLTTMANN HUBERTUS [DE]; WIDMAIER RALF [DE]; PIEROBON MARIANNA [DE]


Application No.: US20080299269A1  Published: 04/Dec/2008

Title: Method And Device For Releasing A Perfume Or Scent

Applicant/Assignee:

Application No.: 12/159393   Filing Date: 22/Dec/2006

Abstract:

A method for masking or modifying the olfactory or gustatory sensation generated in a user by a base product (7) includes releasing an aromatic or fragrant composition over time in a sequenced manner in relation to the release of the base product (7), the aromatic or fragrant composition being housed in at least one rupturable container (5). A device used to implement the method is also disclosed.

Priority: FR20050013425 Applic. Date: 2005-12-28; WO2006FR02862 Applic. Date: 2006-12-22

Inventor: MANE JEAN [FR]; AGUADISCH LOUIS [FR]; STALET GILLES [FR]


Application No.: US20080299510A1  Published: 04/Dec/2008

Title: METHOD AND APPARATUS FOR TEMPORARY DENTAL VENEERS

Applicant/Assignee:

Application No.: 11/757854   Filing Date: 04/Jun/2007

Abstract:

A method for applying a temporary dental veneer on a patient's teeth that includes the steps of positioning a mold on the patient's teeth, the mold containing a material that may be hardened, and hardening the material on the patient's teeth, the hardened material being temporarily affixed on the teeth. The temporarily affixed hardened material becomes unfixed from the patient's teeth from two hours to two weeks after the material is hardened. An apparatus according to the invention includes a mold adapted to receive a material that may be hardened, and a material that may be hardened, wherein the hardened material is adapted to be temporarily affixed to a patient's teeth.

Priority:

Inventor: PENCHAS JONATHAN [US]; KLINE RICK [US]


Application No.: US20080299519A1  Published: 04/Dec/2008

Title: Dental Methods, Compositions, and Kits Including Acid-Sensitive Dyes

Applicant/Assignee:

Application No.: 11/571762   Filing Date: 07/Jul/2005

Abstract:

Methods and compositions including an aqueous liquid that includes an acid-sensitive dye are disclosed for use in dental and orthodontic procedures. The aqueous liquid can be useful for providing a visible color change to indicate contact with acidic materials including, for example, etching compositions, self-etching adhesives, and self-adhesive compositions.

Priority: US20040586326P Applic. Date: 2004-07-08; US20040600558P Applic. Date: 2004-08-11; WO2005US24291 Applic. Date: 2005-07-07

Inventor: CRAIG BRADLEY D [US]; LEE ROBERT [US]; ABUELYAMAN AHMED S [US]; FALSAFI AFSHIN [US]; AASEN STEVEN M [US]; OXMAN JOEL D [US]


Application No.: US20080299520A1  Published: 04/Dec/2008

Title: Foamable Dental Compositions and Methods

Applicant/Assignee:

Application No.: 12/159253   Filing Date: 22/Dec/2006

Abstract:

A foamable dental composition that includes a film-forming component, wherein the film-forming component forms a retentive polymeric coating on a dental surface.

Priority: US20050754684P Applic. Date: 2005-12-29; WO2006US49248 Applic. Date: 2006-12-22

Inventor: ALI MAHFUZA B [US]; BURGIO PAUL A [US]; MITRA SUMITA B [US]


Application No.: US20080300236A1  Published: 04/Dec/2008

Title: QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR

Applicant/Assignee:

Application No.: 12/174017   Filing Date: 16/Jul/2008

Abstract:

This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to quinoline-derived amides that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.

Priority: US2004-770204 Applic. Date: 2004-02-02; US20030444442P Applic. Date: 2003-02-03

Inventor: CODD ELLEN [US]; DAX SCOTT L [US]; JETTER MICHELE [US]; MCDONNELL MARK [US]; MCNALLY JAMES J [US]; YOUNGMAN MARK [US]


Application No.: US20080300242A1  Published: 04/Dec/2008

Title: Imidazopyridine Kinase Inhibitors

Applicant/Assignee:

Application No.: 12/128099   Filing Date: 28/May/2008

Abstract:

The present invention provides imidazopyridine compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.

Priority: US20070941423P Applic. Date: 2007-06-01; US20080024294P Applic. Date: 2008-01-29; US20080035135P Applic. Date: 2008-03-10

Inventor: KUNTZ KEVIN [US]; UEHLING DAVID EDWARD [US]; WATERSON ALEX GREGORY [US]; EMMITTE KYLE ALLEN [US]; STEVENS KIRK [US]; SHOTWELL JOHN BRAD [US]; SMITH STEPHON CORNELL [US]; NAILOR KRISTEN E [US]; SALOVICH JAMES M [US]; WILSON BRIAN JOHN [US]; CHEUNG MUI [US]; MOOK ROBERT ANTHONY [US]; BAUM ERICH W [US]; MOORTHY GANESH [US]


Application No.: US20080300340A1  Published: 04/Dec/2008

Title: Self-healing dental composites and related methods

Applicant/Assignee:

Application No.: 11/809248   Filing Date: 31/May/2007

Abstract:

Dental restorative composites having self-healing capabilities to repair discontinuities in the composite are provided. Dental restorative composites according to the present invention include a microsphere that encapsulates a monomer. When a fracture occurs, the microsphere is ruptured and the monomer fills the fracture. Depending on the monomer present in the microsphere, it is polymerized by a polymerization initiator or by an olefin metathesis catalyst present in the dental restorative composite. Self-healing dental restorative composites provide increased resistance to fracturing, and thus remain substantially intact for a longer period of time, preserving the remedial integrity of the dental repair or reconstruction.

Priority:

Inventor: GROSS STEPHEN M [US]; LATTA MARK A [US]


Application No.: US20080300529A1  Published: 04/Dec/2008

Title: Skin Care Method and Kit Using Peltier Thermoelectric Device

Applicant/Assignee: FARR LABORATORIES, LLC

Application No.: 12/133105   Filing Date: 04/Jun/2008

Abstract:

One embodiment provides a method of treating the skin or body part, comprising contacting the skin or body part with a composition

and contacting the composition and heating and/or cooling the skin or body part with a thermoelectric Peltier device. Another embodiment provides a skin care kit, which comprises a composition suitable for application to the skin

and a thermoelectric Peltier device configured to contact the composition and to heat and/or cool the skin. Other embodiments are also disclosed.

Priority: US20070941929P Applic. Date: 2007-06-04

Inventor: REINSTEIN FRED M [US]


Application No.: US20080300569A1  Published: 04/Dec/2008

Title: Storage-Stable Oral Dosage Form of Amoxicillin and Clavulanic Acid

Applicant/Assignee: GRUENENTHAL GMBH

Application No.: 12/192784   Filing Date: 15/Aug/2008

Abstract:

An airtight-packaged system including: (1) a combination of two independently prepared pharmaceutical drug forms composed of a first drug form in aqueous formulation containing amoxicillin trihydrate as active pharmaceutical ingredient and a second drug form prepared separately from the first and containing potassium clavulanate as active pharmaceutical ingredient, in which the active ingredients in the combination of the first and second drug forms are present in a nominal weight ratio of amoxicillin to clavulanic acid of from 20:1 to 1:1, and (2) a preparation containing at least one desiccant in amounts such that when the packaged system is stored under stress conditions at 40 DEG C. and 75% relative humidity for up to 3 months, the dimerization of amoxicillin trihydrate does not exceed 1.5% by weight, and the degradation of clavulanic acid does not exceed 10% by weight.

Priority: DE200610007830 Applic. Date: 2006-02-17; WO2007EP01335 Applic. Date: 2007-02-15

Inventor: SCHATEIKIS DIETER [DE]; STERNBERGER ELKE [DE]; ZIEGLER IRIS [DE]


Application No.: US20080302836A1  Published: 11/Dec/2008

Title: Multipart Plastic Closure

Applicant/Assignee:

Application No.: 11/886016   Filing Date: 01/Mar/2006

Abstract:

A multi-part plastic closure that accommodates an increased inner pressure in the receptacle on which the closure is attached, while avoiding deformations which compromise the tightness or sealing of the closure. The corresponding multi-part plastic closure includes a lower part having a first region with a lateral surface, with an inner thread for screwing onto a receptacle, and which is closed to the top by a pour-out mouth or spout. The pour-out mouth or spout includes a top surface or covering area which is reduced as an annular sealing surface and is reinforced by stiffening. A centric pour-out opening or central spout is provided with a sealing, and a sealing plug or peg which is integrally formed or molded on the lower side or bottom face of a screw cap capable of being put on, moves into the central pour-out opening or spout. One or more drinking openings are molded or formed in the region of the lateral wall of the screw cap and the sealing plug or peg in the top surface. The multi-part plastic closure configured in such a manner is also capable of sealing relatively high inner pressures in the receptacle.

Priority: CH20050000405 Applic. Date: 2005-03-09; WO2006CH00126 Applic. Date: 2006-03-01

Inventor: MATHIS LORENZ [AT]


Application No.: US20080305051A1  Published: 11/Dec/2008

Title: Menthane Carboxamide Derivatives Having Cooling Properties

Applicant/Assignee:

Application No.: 11/884479   Filing Date: 23/Feb/2006

Abstract:

A compound of the formula I in which X and Y are selected as follows: (i) X is H and Y is selected from the group consisting of (ii) X and Y together form a bivalent radical selected from the group consisting of -O-CH2-O-, -N-CH-O- and -N-CH-S- thus forming together with the carbon atoms to which the radical is attached a 5-membered ring. The compounds have cooling properties and are useful in, for example, foodstuffs, dentifrices and cosmetics.

Priority: US20050657562P Applic. Date: 2005-03-01; WO2006CH00116 Applic. Date: 2006-02-23

Inventor: COLE LUCIENNE [US]; FURRER STEFAN MICHAEL [US]; GALOPIN CHRISTOPHE C [US]; KRAWEC PABLO VICTOR [US]; MAZUR ADAM [US]; SLACK JAY PATRICK [US]


Application No.: US20080305457A1  Published: 11/Dec/2008

Title: Methods of Applying Dental Agents to Dental Surfaces and Polymer Compositions

Applicant/Assignee:

Application No.: 12/159464   Filing Date: 28/Dec/2006

Abstract:

A method of applying a dental agent to a dental surface, the method including: applying a retentive polymeric coating to a dental surface

and subsequently contacting the retentive polymeric coating with a loading composition that includes a dental agent, wherein the contacting occurs under conditions effective to incorporate the dental agent into the retentive polymeric coating for release over time. Also provided are polymers that include a hydrophobic segment, a hydrophilic segment, a quaternary amine segment, and an alkoxy silane crosslinkable segment

and polymers that include a hydrophobic segment, a hydrophilic segment, a silicon-containing macromer segment, and an alkoxy silane crosslinkable segment.

Priority: US20050754934P Applic. Date: 2005-12-29; WO2006US49467 Applic. Date: 2006-12-28

Inventor: ALI MAHFUZA B [US]; BURGIO PAUL A [US]; MITRA SUMITA B [US]


Application No.: US20080305548A1  Published: 11/Dec/2008

Title: METHOD FOR STIMULATING SALIVA PRODUCTION DURING ORAL SAMPLE COLLECTION PROCEDURE

Applicant/Assignee: AMERICAN BIO MEDICA CORPORATION

Application No.: 11/760977   Filing Date: 11/Jun/2007

Abstract:

A method and device are provided for stimulating and increasing the production of saliva during immunoassay tests for drugs or other analytes wherein a scent or odor capable of stimulating saliva production is incorporated into a device for obtaining an oral sample from a test subject. The scent or odor may be impregnated into the oral sample collection device or may be part of an attachment to such a device, and the scent or odor is disposed in such a manner so as to maximize the exposure of the scent to the test subject and thus stimulate the production of saliva. The method and device of the invention are advantageous because the increased production of saliva will facilitate the testing of an oral sample for drugs or other analytes and will increase the likelihood of obtaining a complete and accurate result.

Priority:

Inventor: GOULD MARTIN [US]; SMALLEY ROBERT [US]; BERNSTINE ROB [US]


Application No.: US20080306078A1  Published: 11/Dec/2008

Title: 3,9-Diazabicyclo [3.3.1] Nonane Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee: NEUROSEARCH A/S

Application No.: 12/159074   Filing Date: 09/Feb/2007

Abstract:

This invention relates to novel 3,9-diazabicyclo[3.3.1]nonane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20060000191 Applic. Date: 2006-02-10; US20060771889P Applic. Date: 2006-02-10; WO2007EP51271 Applic. Date: 2007-02-09

Inventor: PETERS DAN [SE]; REDROBE JOHN PAUL [DK]; NIELSEN ELSEBET OSTERGAARD [DK]


Application No.: US20080306168A1  Published: 11/Dec/2008

Title: Dental Compositions with a Water Scavenger

Applicant/Assignee:

Application No.: 12/159243   Filing Date: 28/Dec/2006

Abstract:

The present invention relates to polymerizable dental compositions that contain a water scavenger, such as a molecular sieve, to increase the shelf life of the composition.

Priority: US20050754953P Applic. Date: 2005-12-29; WO2006US49427 Applic. Date: 2006-12-28

Inventor: CRAIG BRADLEY D [US]; HOLMES BRIAN N [US]; AASEN STEVEN M [US]; HANSEN JAMES D [US]; SHUKLA BRIAN A [US]


Application No.: US20080306182A1  Published: 11/Dec/2008

Title: Reactive filler for dental cements

Applicant/Assignee:

Application No.: 12/221637   Filing Date: 05/Aug/2008

Abstract:

A process' for the modification of a particulate reactive filler for a dental ionomer cement, comprising (a) providing a particulate reactive filler

and (b1) treating the surface of the particulate reactive filler with a surface modifying agent for obtaining a surface modified particulate reactive filler displaying ligand groups for a transition metal

and (b2) treating the surface modified particulate reactive filler with an agent containing the transition metal for complexing the transition metal with the ligand groups displayed on the surface of the surface modified particulate reactive filler

and/or (c) treating the surface of the particulate reactive filler with a surface modifying transition metal complex which is a reaction product of a surface modifying agent and a transition metal precursor compound, for obtaining a transition metal complex surface modified particulate reactive filler for a dental ionomer cement.

Priority: EP20040018746 Applic. Date: 2004-08-06; US2005-218772 Applic. Date: 2005-09-02; US20040606509P Applic. Date: 2004-09-02

Inventor: BRUGGER STEFAN [DE]; SCHELLONG ALICE [DE]


Application No.: US20080308106A1  Published: 18/Dec/2008

Title: PERSONAL AIR FILTRATION DEVICE

Applicant/Assignee: AUGUSTINE BIOMEDICAL AND DESIGN, LLC

Application No.: 12/037078   Filing Date: 25/Feb/2008

Abstract:

A personal air filtration device and methods of using the same for providing a zone of filtered air proximate a breathing zone of a user are described. A blower provides an air flow to a head support which delivers the air flow to a zone proximate the users head. The air flow passes through a filter. The filter can be a point of delivery filter disposed about an air permeable surface of the head support. The delivered air flow can provide a laminar air flow defining a zone of filtered air about the user's breathing zone.

Priority: US20070891395P Applic. Date: 2007-02-23; US20070891390P Applic. Date: 2007-02-23; US20070891400P Applic. Date: 2007-02-23; US20070891708P Applic. Date: 2007-02-26

Inventor: AUGUSTINE SCOTT D [US]; ALBRECHT MARK C [US]; ARNOLD RANDALL C [US]; AUGUSTINE RYAN S [US]; BARROWS RYAN [US]; MCGREGOR ANDREW [US]


Application No.: US20080308450A1  Published: 18/Dec/2008

Title: KIT FOR FABRICATING AND MAINTAINING DENTURES AND DENTAL APPARATUS AND FOR PERSONAL PROFESSIONAL TOOTH WHITENING BY AUTONOMOUS DENTAL IMPRESSION TAKING

Applicant/Assignee:

Application No.: 12/136922   Filing Date: 11/Jun/2008

Abstract:

The present invention relates to a kit for whitening teeth and a kit for fabricating a dental apparatus and/or denture without visiting the dentist or stomataologist.

Priority: US20070943605P Applic. Date: 2007-06-13

Inventor: TCHOUANGANG LYDIE LIVOLSI [US]


Application No.: US20080311054A1  Published: 18/Dec/2008

Title: Compositions and Methods to Counteract Oral Malodour

Applicant/Assignee: GIVAUDAN SA

Application No.: 12/064506   Filing Date: 24/Aug/2006

Abstract:

The invention relates to hedonistically pleasing oral malodour counteracting compositions including flavour compositions and oral care products, methods to form such compositions and methods to counteract oral malodour. The compositions comprises 2 or more of oral malodour counteracting actives of formula I in a total concentration of at least 10% (w/w) based on the total concentration of flavour ingredients, and an individual concentration of 1% or more per oral malodour counteractant, based on total flavour ingredients. The maximum concentration of any individual oral malodour counteracting active based on the total of oral malodour counteracting actives is 70%. The identified oral malodour counteracting actives are various flavour compounds and natural ingredients.

Priority: GB20050017577 Applic. Date: 2005-08-30; WO2006CH00460 Applic. Date: 2006-08-24

Inventor: NATSCH ANDREAS [CH]; MORAES EDUARDO [CH]


Application No.: US20080311055A1  Published: 18/Dec/2008

Title: MONO-, DI- AND POLYOL ALKOXYLATE PHOSPHATE ESTERS IN ORAL CARE FORMULATIONS AND METHODS FOR USING SAME

Applicant/Assignee: RHODIA INC

Application No.: 12/137647   Filing Date: 12/Jun/2008

Abstract:

This invention relates to a composition useful as an oral care composition comprising an organophosphate material, additional oral care composition ingredients, for example, a surfactant agent, and optionally an abrasive agent.

Priority: US20070943490P Applic. Date: 2007-06-12

Inventor: FUTTERER TOBIAS JOHANNES [SG]; HOUGH LAWRENCE ALAN [US]; REIERSON ROBERT LEE [US]


Application No.: US20080311057A1  Published: 18/Dec/2008

Title: Bleaching Toothpastes and Methods for Making and Using Them

Applicant/Assignee: CAO GROUP, INC

Application No.: 12/198226   Filing Date: 26/Aug/2008

Abstract:

In toothpaste, the addition of the Iodide ion by way of iodide salts, such as sodium iodide and potassium iodide, to a peroxide such as hydrogen peroxide in a basic medium yields free radical oxygen and water

generating large amounts of heat and depleting the Hydrogen Peroxide in a matter of minutes. The free radical oxygen generated in this reaction can be utilized to oxidize organic molecules that produce offending stains on select items, including artificial teeth and other dental appliances. Once the free radical oxygen has oxidized the offending molecule the color is lost and the solubility changes allowing any loose fragments of the offending molecule to be washed away in the solvent. The iodide ion catalyzes the reaction allowing for precise control over the speed at which the stain is removed without the need for other expensive, cumbersome energy adding equipment such as lights, lasers, heat sources, etc.

Priority: US2004-922375 Applic. Date: 2004-08-20

Inventor: LARSEN ROBERT K [US]; OSTLER CALVIN D [US]


Application No.: US20080311103A1  Published: 18/Dec/2008

Title: Anti-Inflammatory Peptides and Methods of Use Thereof

Applicant/Assignee: YEDA RESEARCH AND DEVELOPMENT CO. LTD. AT THE WEIZMANN INSTITUTE OF SCIENCE

Application No.: 10/592163   Filing Date: 08/Mar/2005

Abstract:

Anti-inflammatory peptides derived from naturally occurring digests of proteins including apolipoprotein A-I, apolipoprotein A-II, fibrinogen gamma chain, fibrinogen Aa, low-density lipoprotein receptor, ADAM 8, cadherin 4, and calcitonin receptor are provided, along with pharmaceutical compositions comprising same and methods of treating inflammatory diseases using same.

Priority: US20040550307P Applic. Date: 2004-03-08; WO2005IL00272 Applic. Date: 2005-03-08

Inventor: LIDER OFER [IL]; CAHALON LIORA [IL]; LIDER OSNAT [IL]; LIDER LIHI [IL]


Application No.: US20080311107A1  Published: 18/Dec/2008

Title: Novel Gene Disruptions, Compositions and Methods Relating Thereto

Applicant/Assignee: GENETECH, INC

Application No.: 11/814136   Filing Date: 09/Feb/2007

Abstract:

The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO188, PRO235, PRO266, PRO337, PRO361, PRO539, PRO698, PRO717, PRO846, PRO874, PRO98346, PRO1082, PRO1097, PRO1192, PRO1268, PRO1278, PRO1303, PRO1308, PRO1338, PRO1378, PRO1415, PRO1867, PRO1890, PRO3438, PRO19835, PRO36915, PRO36029, PRO4999, PRO5778, PRO5997, PRO6079, PRO6090, PRO7178, PRO21184, PRO7434, PRO9822, PRO9833, PRO9836, PRO9854, PRO9862, PRO10284, PRO37510, PRO35444, PRO20473, PRO21054 or PRO35246 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders

cardiovascular, endothelial or angiogenic disorders

eye abnormalities

immunological disorders

oncological disorders

bone metabolic abnormalities or disorders

lipid metabolic disorders

or developmental abnormalities.

Priority: US20060774895P Applic. Date: 2006-02-17; WO2007US61927 Applic. Date: 2007-02-09

Inventor: BOLLINGER KRISTI RAE [US]; COMBS KATHERIN E [US]; CUNNINGHAM JAIME-JO [US]; CULBERTSON LING LING [US]; DE SAUVAGE FREDERIC J [US]; EDWARDS JOEL A [US]; GREEN LESLIE JANE [US]; GIRGIS ROSEMARY [US]; HORNER ALLISON ANNE BYERS [US]; MCLAIN DINA REBECCA [US]; MONTGOMERY CHARLES [US]; MINZE LAURIE JEANETTE [US]; PAYNE BOBBY JOE [US]; PHILLIPS HEIDI [US]; SEVAUX TRAC ELLEN WILLIS [US]; SHI ZHENG-ZHENG [US]; SPARKS MARY JEAN [US]; STALA JOY ANNE [US]; TANG TRACY TZU-LING [US]; TOWNSEND TERESA GAIL [US]; VOGEL PETER [US]


Application No.: US20080311167A1  Published: 18/Dec/2008

Title: Topical Composition for Treating Pain

Applicant/Assignee:

Application No.: 11/851241   Filing Date: 06/Sep/2007

Abstract:

Topical compositions having as the active ingredient a lipid, fatty acid ester, natural wax, sterol, or combinations thereof referred to herein as "lipophilic vehicle" or "LV" and methods of use, have been developed for the amelioration or prevention of pain or the sequelae of pain. The composition may be in the form of an ointment, cream, gel, lotion, spray, foam, paste, patch, suspension or dispersion. In the preferred embodiment, the formulation is a gel. The LV may contain a penetration enhancer, most preferably one with membrane disruptive properties. The formulation may be applied to or impregnated into a gauze, wrap, bandage, cotton-tipped stick, adhesive bandage strip, or other support wrap or medical bandage or wound cover. For example, the compositions may be are incorporated onto or into disposables such as hemorrhoid wipes, sponge, mouth guards, dental trays

needles or catheters

adult diapers

gloves, socks or wrist bands, for ease of application. The composition is applied topically to a site at or adjacent to a painful region. The composition is reapplied as necessary. Pain relief is typically obtained within minutes and lasts for periods of variable duration ranging from minutes to several hours and even, in some cases, days. The composition is variably effective to treat visceral, somatic and neuropathic pain both acute and chronic as well as muscle pain and stiffness and joint pain and stiffness.

Priority: US20070943552P Applic. Date: 2007-06-12

Inventor: ORONSKY BRYAN T [US]; ORONSKY NEIL C [US]; ORONSKY ARNOLD L [US]


Application No.: US20080311216A1  Published: 18/Dec/2008

Title: Epidermal Growth Factor Composition, A Process Therefor and Its Application

Applicant/Assignee: BHARAT BIOTECH INTERNATIONAL LIMITED

Application No.: 11/915727   Filing Date: 18/May/2006

Abstract:

A composition for treating a wound, wherein the composition can comprise therapeutically effective amount of an epidermal growth factor and a physiologically acceptable agent, wherein the physiologically acceptable agent comprises at least one of a stabilizer, a preservative, a thickening agent, carrier/diluent, and optionally pH regulating agent and humectant.

Priority: IN2005CH00642 Applic. Date: 2005-05-27; WO2006IN00168 Applic. Date: 2006-05-18

Inventor: ELLA KRISHNA MURTHY [IN]; VELLIMEDU SRINIVAS KANNAPPA [IN]


Application No.: US20080311540A1  Published: 18/Dec/2008

Title: Method and Device For Removing Biofilms By Microsteaming

Applicant/Assignee: KONINKLIJKE PHILIPS ELECTRONICS, N.V

Application No.: 12/094187   Filing Date: 27/Oct/2006

Abstract:

A method of removing bio films from a surface is disclosed. The method includes a source of bubbles in a liquid medium being provided. The bubbles having a predetermined size. A source of ultrasound waves at a predetermined frequency also being provided. The bubbles in the liquid medium being output toward the surface. The ultrasound waves also being directed toward the surface so that the bubbles vibrate at the predetermined frequency of the ultrasound waves. The predetermined size of the bubbles is approximately related to the frequency of the ultrasound waves.

Priority: US20050740158P Applic. Date: 2005-11-28; WO2006IB54463 Applic. Date: 2006-11-27

Inventor: GOTTENBOS BART [NL]; JANSSEN JOEP [NL]; NUIJS ANTONIUS MAARTEN [NL]


Application No.: US20080312145A1  Published: 18/Dec/2008

Title: Agent for Regulating Bone Formation

Applicant/Assignee: ANGES MG, INC

Application No.: 11/721834   Filing Date: 15/Dec/2005

Abstract:

The present invention provides preventive, ameliorating, and/or therapeutic agents for diseases caused by a disturbed balance between bone formation and bone resorption. The decoys of the present invention induce normal bone metabolism by inhibiting the differentiation-inducing factors of cells involved in bone metabolism. For example, bone resorption can be controlled by using a decoy of the present invention to inhibit NF-kappaB, a transcriptional regulatory factor that regulates osteoclast differentiation. This method uses a mechanism different from those of previous pharmaceutical agents

therefore, one can expect it to be effective for cases in which existing pharmaceutical agents were not effective.

Priority: JP20040365148 Applic. Date: 2004-12-16; JP20050234311 Applic. Date: 2005-08-12; WO2005JP23078 Applic. Date: 2005-12-15

Inventor: SHIMIZU HIDEO [JP]; NAKAGAMI HIRONORI [JP]; MORISHITA RYUICHI [JP]


Application No.: US20080312234A1  Published: 18/Dec/2008

Title: NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST

Applicant/Assignee: AMOREPACIFIC CORPORATION

Application No.: 11/829531   Filing Date: 27/Jul/2007

Abstract:

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1

VR1

TRPV1) antagonist

and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, heart disease and so on.

Priority: EP20060015724 Applic. Date: 2006-07-27; EP20060020620 Applic. Date: 2006-09-29; EP20070004194 Applic. Date: 2007-02-28; US20070893974P Applic. Date: 2007-03-09

Inventor: KIM SUN-YOUNG [KR]; KIM JIN KWAN [KR]; LEE KI-WHA [KR]; WOO BYOUNG YOUNG [KR]; SHIN SONG SEOK [KR]; MOH JOO-HYUN [KR]; KIM SUNG-IL [KR]; JEONG YEON SU [KR]; LIM KYUNG MIN [KR]; CHOI JIN KYU [KR]; HA JUN YONG [KR]; KOH HYUN-JU [KR]; PARK YOUNG-HO [KR]; SUH YOUNG-GER [KR]; KIM HEE-DOO [KR]; PARK HYEUNG-GEUN [KR]; OH UH TAEK [KR]


Application No.: US20080312237A1  Published: 18/Dec/2008

Title: Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same

Applicant/Assignee: RENOVIS, INC

Application No.: 12/218973   Filing Date: 18/Jul/2008

Abstract:

Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

Priority: US2004-961483 Applic. Date: 2004-10-07; US20030508884P Applic. Date: 2003-10-07

Inventor: KELLY MICHAEL G [US]; JANAGANI SATYANARAYANA [US]; UPASANI RAVINDRA B [US]


Application No.: US20080312287A1  Published: 18/Dec/2008

Title: Compound and Methods For the Treatment of Cancer and Malaria

Applicant/Assignee: UNIVERSITY OF WASHINGTON

Application No.: 11/886105   Filing Date: 17/Mar/2006

Abstract:

Formula (I): Where R1 is an optionally substituted C3-C12 hydrocarbyl group (preferably a cyclic alkyl group), an optionally substituted heterocyclic group, an optionally substituted aromatic group or an optionally substituted heteroaromatic group

R is a C(O)yR' group (preferably forming an optionally substituted C2-C5 acyl group), or a S(O)xR' group, where y is 0 or 1 and x is 0, 1 or 2 and R' is H or an optionally substituted C1-C12 alkyl group, or R' is an optionally substituted C5-C12 cycloalkyl group, an optionally substituted heterocyclic group, an optionally substituted aromatic group or an optionally substituted heteroaromatic group

R5, R6, R7, R8, R9 and R10 are each independently selected from H, an optionally substituted C1-C12 hydrocarbyl group, including a C5-C12 cycloalkyl group, an optionally substituted heterocyclic group, an optionally substituted aromatic group or an optionally substituted heteroaromatic group, or R5 and R6, R7 and R8 or R9 and R10 together form a keto (C-O) group

RN is H, an optionally substituted C1-C12 hydrocarbyl group, an optionally substituted heterocyclic group, an optionally substituted aromatic group, or an optionally substituted heteroaromatic group

A is Formula (II): a Formula (III): group, or a Formula (IV) or Formula (V) group, where Z is N, O or S

Ra is H, a C1-C12 optionally substituted hydrocarbyl group or an optionally substituted aromatic group

n is from 0 to 3

and pharmaceutically acceptable salts thereof. Compounds according to the invention are useful in one or more aspects to inhibit farnesyl transferase, or to treat malaria, neoplasia, a hyperproliferative disease state or arthritis, including rheumaroid arthritis or osteoarthritis.

Priority: US20050663370P Applic. Date: 2005-03-17; WO2006US09861 Applic. Date: 2006-03-17

Inventor: HAMILTON ANDREW [US]; BUCKNER FREDERICK [US]; GLENN MATTHEW [AU]; VAN VOORHIS WESLEY [US]; SEBTI SAID [US]


Application No.: US20080313828A1  Published: 25/Dec/2008

Title: Power Toothbrush Using Acoustic Wave Action For Cleansing of Teeth

Applicant/Assignee: KONINKLIJKE PHILIPS ELECTRONICS N.V

Application No.: 11/813918   Filing Date: 13/Jul/2007

Abstract:

The toothbrush includes a handle portion and a brushhead assembly which comprises a head portion and a stem portion. The head portion includes a bellows-like acoustic action member for creating acoustic wave action as it moves in and out in response to an acoustic driving force. A drive system is located in the handle and includes an audio speaker-type assembly to create acoustic waves which are transmitted through a transmission line to the acoustic action member. The acoustic action member is driven toward and away from the teeth when the toothbrush is operatively positioned within the mouth. The action of the acoustic member is directly or indirectly coupled to the fluid in the mouth, producing a foam which couples shear forces between the acoustic action member and the teeth/gums to produce a desired cleaning/therapeutic effect.

Priority: US20030483149P Applic. Date: 2003-06-27; WO2004IB51013 Applic. Date: 2004-06-25

Inventor: GREZ JOSEPH [US]


Application No.: US20080314286A1  Published: 25/Dec/2008

Title: Reactive Particles, Production Thereof, and Use Thereof in Kits and Cements

Applicant/Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWAND E.V

Application No.: 12/091750   Filing Date: 07/Nov/2006

Abstract:

Ionomer particles with an inner area and an outer area are provided. The outer area has an oxidic matrix with cations selected by observing the following conditions. Only two different types of cations must be present that belong to one of the following groups (a) to (d), and these two types of cations must be selected from two different ones of the groups (a) to (d): (a) ions of the elements of the second main group and bivalent ions of the transition elements and the lanthanides

(b) ions of the elements of the third main group with the exception of boron and trivalent ions of the transition elements and the lanthanides

(c) ions of the elements of the fourth main group with exception of carbon and tetravalent ions of the transition elements and the lanthanides (d) ions of the elements of the fifth main group, selected from ions of antimony and bismuth and pentavalent ions of the transition elements. Particles of the composition ZrO2-Y2O3, ZrO2-Al2O3, BaToO3, Al6Si2O13 are not contained.

Priority: DE200510053721 Applic. Date: 2005-11-10; WO2006EP68186 Applic. Date: 2006-11-07

Inventor: GELLERMANN CARSTEN [DE]; WOLTER HERBERT [DE]; BALLWEG THOMAS [DE]


Application No.: US20080314406A1  Published: 25/Dec/2008

Title: METHODS AND APPARATUS FOR TEXTURED DENTAL FLOSS

Applicant/Assignee:

Application No.: 12/141293   Filing Date: 18/Jun/2008

Abstract:

Methods and apparatus for textured dental floss according to various aspects of the present invention may operate in conjunction with a flexible substrate that may be placed in interdental spaces. In one embodiment, the flexible substrate may comprise at least one node affixed to the flexible substrate to assist in removal of plaque and particulate matter, to massage the gums and/or to deliver one or more additives.

Priority: US20070944725P Applic. Date: 2007-06-18

Inventor: BARRIE DARWIN N [US]


Application No.: US20080314775A1  Published: 25/Dec/2008

Title: Low-Cost, Mass-Producible Container for Separately Storing at Least Two Substances of Any Ratio for Subsequent Mixing, a.k.a., "TIDAL TWIST" and "TIDAL FORCE"

Applicant/Assignee:

Application No.: 11/766930   Filing Date: 22/Jun/2007

Abstract:

A container for storing at least two substances separately, for subsequent mixing, comprises two storage chambers. Both substances are maintained separately through means of an intervening seal that in one embodiment includes molded threads on its inner walls, a breakable bottom, and a seal rim portion. Activation occurs when the first chamber is screwed downward toward the second chamber. A second embodiment includes the same seal, but with no threads and simply a press activation system within a bellows sleeve. The first chamber may include various cap means through which the mixed substances may be poured out, including screw, spouted, snap-fitted, and plug-types. The seals of both embodiments may be reconfigured into two parts to adapt to a modified second chamber to accomplish the same results. The container may be enclosed in tamper-evident film that includes a perforated pull strip. Both embodiments can be adapted for beverage, medical, cosmetic, chemical, and many other container applications.

Priority:

Inventor: OWOC GREG J [US]


Application No.: US20080317681A1  Published: 25/Dec/2008

Title: Compositions containing a stain removing complex, and methods of making and using the same

Applicant/Assignee:

Application No.: 12/074927   Filing Date: 07/Mar/2008

Abstract:

A composition in the form of a chewing gum composition, a confectionery composition or consumable film composition containing a stain removing complex including a stain removing agent having therapeutic properties and a cyclodextrin compound and methods of preparing and using the same to remove stains from dental material including teeth.

Priority: US2003-618202 Applic. Date: 2003-07-11

Inventor: GEBRESELASSIE PETROS [US]; LUO SHIUH JOHN [US]; BOGHANI NAVROZ [US]


Application No.: US20080317765A1  Published: 25/Dec/2008

Title: Method for Removal of Toxins from Mucosal Membranes

Applicant/Assignee: POLYRIZON LTD

Application No.: 11/885340   Filing Date: 02/Mar/2006

Abstract:

The present invention provides novel mucoadhesive compounds useful in the prevention of diseases and disorders of or which arc associated with the mucosal membrane.

Priority: US20050657388P Applic. Date: 2005-03-02; US20050738973P Applic. Date: 2005-11-23; WO2006IL00291 Applic. Date: 2006-03-02

Inventor: IZRAELI TOMER [IL]; COHEN SMADAR [IL]; MARKS ROBERT S [IL]


Application No.: US20080317789A1  Published: 25/Dec/2008

Title: Carrageenan Process

Applicant/Assignee: CP KELCO U.S., INC

Application No.: 11/767676   Filing Date: 25/Jun/2007

Abstract:

The present invention discloses a process for treating precipitated carrageenan, comprising the steps of (a) treating the precipitated carrageenan with an aqueous treatment solution containing an alkali or a salt, (b) washing the treated precipitated carrageenan in water, and (c) drying the washed precipitated carrageenan.

Priority:

Inventor: TRUDSO JENS ESKIL [DK]


Application No.: US20080317790A1  Published: 25/Dec/2008

Title: Process for Treatment of Kappa Carrageenan

Applicant/Assignee: CP KELCO U.S., INC

Application No.: 11/767729   Filing Date: 25/Jun/2007

Abstract:

The present invention relates to a process for treating precipitated carrageenan, comprising the steps of (a) treating the precipitated carrageenan with an aqueous treatment solution containing an alkali or a salt, (b) washing the treated precipitated carrageenan in water, and (c) drying the washed precipitated carrageenan.

Priority:

Inventor: TRUDSOE JENS ESKIL [DK]


Application No.: US20080317795A1  Published: 25/Dec/2008

Title: HIGHLY CHARGED MICROCAPSULES

Applicant/Assignee:

Application No.: 12/125035   Filing Date: 21/May/2008

Abstract:

The invention encompasses compositions containing sol-gel microcapsules that are highly positively charged. The sol-gel capsules generally contain additives. The invention also encompasses methods for producing highly charged microcapsules using cationic additives which can include cationic polymers. The methods allow for the encapsulation of polar or non-polar active ingredients.

Priority: US20070939318P Applic. Date: 2007-05-21

Inventor: TRAYNOR DANIEL HENRY [US]; TRAYNOR HENRY G [US]; MARKOWITZ STEVEN M [US]; COMPTON DAVID L [US]


Application No.: US20080317797A1  Published: 25/Dec/2008

Title: TOOTH WHITENING PRODUCTS AND METHODS OF MAKING THE SAME

Applicant/Assignee: LORNAMEAD BRANDS, INC

Application No.: 12/202747   Filing Date: 02/Sep/2008

Abstract:

A dissolving strip for tooth whitening the strip having at least a first tooth contacting layer and a second outer layer. The first tooth contacting layer has a solid tooth whitening active in an amount which reacts within a predetermined time when placed on a tooth. The second outer layer has a blend of polymers having different molecular weights

the blend of polymers being selected to dissolve after the predetermined time has elapsed. The outer layer contains the tooth whitening active on said tooth until the active is substantially used up. A method of forming a dissolving tooth whitening strip is also provided, in which the outer layer is formed on a backing layer followed by the inner layer being formed on the outer layer.

Priority: CA20042470463 Applic. Date: 2004-06-09; US2004-975064 Applic. Date: 2004-09-22

Inventor: LOKKEN JEFFERY [US]


Application No.: US20080317815A1  Published: 25/Dec/2008

Title: Induction of a physiological dispersion response in bacterial cells in a biofilm

Applicant/Assignee: RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

Application No.: 12/152347   Filing Date: 14/May/2008

Abstract:

One aspect of the present invention is directed to a composition. The composition includes a dispersion inducer comprising: H3C-(CH2)n-CHmCHmR, where is a single or double carbon-carbon bond, m is 1 or 2, n is 2 to 15, and R is a carboxylic acid, a salt, an ester, or an amide, where the ester or amide is an isostere or biostere of the carboxylic acid. The composition additionally contains an additive component selected from one or more of the group consisting of biocides, surfactants, antibiotics, antiseptics, detergents, chelating agents, virulence factor inhibitors, gels, polymers, pastes, edible products, and chewable products. The composition is formulated so that when it is contacted with a biofilm produced by a microorganism, where the biofilm comprises a matrix and microorganism on a surface, the dispersion inducer selectively acts on the microorganism and has a suitable biological response without a required direct effect on the matrix to disperse the biofilm. The present invention is also directed to methods of using this compound.

Priority: US20070917791P Applic. Date: 2007-05-14; US20080018639P Applic. Date: 2008-01-02

Inventor: DAVIES DAVID G [US]


Application No.: US20080317853A1  Published: 25/Dec/2008

Title: Mouth Dissolving Pharmaceutical Composition and Process for Preparing the Same

Applicant/Assignee: JUBILANT ORGANOSYS LTD

Application No.: 12/097813   Filing Date: 30/Aug/2006

Abstract:

Disclosed herein is a orally disintegrating and/or dissolving oral pharmaceutical composition, comprising one or more active pharmaceutical ingredients, one or more fillers having particle size of 100 microns or above, a high and desirable amount of silicon dioxide, one or more disintegrating agents, optionally effervescent couple, wherein said composition has good organoleptic properties like desired mouth feel and fast oral disintegration time.

Priority: IN2005DE03482 Applic. Date: 2005-12-27; WO2006IN00319 Applic. Date: 2006-08-30

Inventor: KASHID NAMDEV [IN]; MUKHERJI GOUR [IN]


Application No.: US20080317855A1  Published: 25/Dec/2008

Title: Particulate Compositions Comprising Alginate and/or Alginic Acid

Applicant/Assignee: RECKITT BENCKISER HEALTCARE (UK) LIMITED,

Application No.: 11/994359   Filing Date: 27/Jul/2006

Abstract:

An ingestible particulate composition comprises: a. an alginate and/or alginic acid

b. a bicarbonate and/or carbonate

c. an organic acid

and d. an agglomerant, being a compound, such as a low molecular weight polyol, which allows the particulate composition to flow yet which substantially does not release fine particulates into the air. Resulting particulate compositions have excellent flow characteristics, dust suppression, organoleptic properties and stability. They are highly suitable for administration direction into a patient's mouth, and ingested to alleviate oesophageal and gastric conditions.

Priority: GB20050015492 Applic. Date: 2005-07-28; WO2006GB02807 Applic. Date: 2006-07-27

Inventor: JOLLIFFE IAN GORDON [GB]; TRAFFORD CHARLES [GB]; GASEROD OLAV [NO]


Application No.: US20080317887A1  Published: 25/Dec/2008

Title: Compositions and Methods for Treating and Preventing Migrainous Headaches and Associated Symptoms

Applicant/Assignee: PURAMED BIOSCIENCE INC

Application No.: 12/144391   Filing Date: 23/Jun/2008

Abstract:

Compositions and methods of treating migrainous headaches and their associated symptoms are provided. Methods of treating migrainous headaches and their associated symptoms include administering a lipid-based composition containing feverfew extract and ginger extract sublingually to a patient in need thereof. Treatments are effective using low total administered amounts of feverfew and ginger extracts.

Priority: US20070945502P Applic. Date: 2007-06-21

Inventor: MITCHELL RUSSELL W [US]; HIGGINS JAMES W [US]


Application No.: US20080318178A1  Published: 25/Dec/2008

Title: Systems and methods for dental appliance compliance indication

Applicant/Assignee: ALIGN TECHNOLOGY, INC

Application No.: 12/229291   Filing Date: 21/Aug/2008

Abstract:

An apparatus for monitoring orthodontic treatment compliance includes an appliance adapted to be worn over one or more teeth

and a compliance indicator mounted on the appliance to indicate compliance.

Priority: US2004-949717 Applic. Date: 2004-09-24

Inventor: ABOLFATHI AMIR [US]; CHEN JENNIFER C [US]; LI CHUNHUA [US]; TRICCA ROBERT E [US]; WU BENJAMIN M [US]


Application No.: US20080318188A1  Published: 25/Dec/2008

Title: Dimer Acid-Derived Dimethacrylates and Use in Dental Restorative Compositions

Applicant/Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO

Application No.: 11/568383   Filing Date: 29/Dec/2004

Abstract:

The present invention provides polymerizable dental compositions comprising a dimer acid-derived monomer such as a dimer acid-derived di(meth)acrylate monomer. In one embodiment, the dimer acid-derived monomer is of the formula (I): wherein R1, R2, R3, R4, R5 and R6 are independently selected from H and optionally substituted C1-C25 straight-chained or branched aliphatic, optionally containing 1 or more double or triple bonds, wherein one or more carbons are optionally replaced by R* wherein R* is -C(O)-, -C(O)C(O)-, -C(O)NR7-, -C(O)NR7NR8-, -C(O)O-, -OC(O)-, -NR7CO2-, -O-, -NR7C(O)NR8-, -OC(O)NR7-, -NR7NR8-, -NR7C(O)-, -NR7C(O)O-, -S-, -SO-, -SO2-, -NR7-, -SO2NR7- or -NR7SO2-, where R7 and R8 are independently selected from H and optionally substituted aliphatic, cycloalkyl, heterocycloalkyl, aryl or heteroaryl

provided that at least two of R1, R2, R3, R4, R5 and R6 are substituted C1-25 straight-chained or branched aliphatic wherein at least one carbon is replaced by R* and at least one of the substituents is an alkenyl group.

Priority: US20040566299P Applic. Date: 2004-04-28; WO2004US43828 Applic. Date: 2004-12-29

Inventor: STANSBURY JEFFREY W [US]; BOWMAN CHRISTOPHER N [US]; TRUJILLO MARIANELA [US]


Application No.: US20080318190A1  Published: 25/Dec/2008

Title: Polymerizable Dental Pulp Healing, Capping, and Lining Material and Method for Use

Applicant/Assignee: BISCO, INC

Application No.: 12/034093   Filing Date: 20/Feb/2008

Abstract:

Dental pulp healing lining or capping compositions and methods of using the composition to treat an exposed, nearly exposed, or breached pulp chamber are disclosed herein. Embodiments include dental pulp healing lining or capping compositions comprising a resin portion having at least one hydrophilic monomer component and at least one hydrophobic monomer component and a calcareous material operable to both provide a biological seal and maintain an alkaline pH for extended periods. Further, light curable compositions are disclosed, allowing for improved curing properties, and allowing permanent restorations to be adhered to the sealed tooth without waiting a significant amount of time for the Portland cement portion to cure.

Priority: US20070902301P Applic. Date: 2007-02-20

Inventor: SUH BYOUNG [US]; YIN RUI [US]; CANNON MARK [US]; MARTIN DAVID E [US]


Application No.: US20080318860A1  Published: 25/Dec/2008

Title: High Activity Growth Factor Mutants

Applicant/Assignee: BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA MBH

Application No.: 12/094227   Filing Date: 17/Nov/2006

Abstract:

The application relates to novel biosynthetic growth factor mutants, derived from GDF-5, which exhibit improved biological activity. Mutations at positions 453 and 456 of human GDF-5 are disclosed, as well as use of these mutants in therapy of diseases associated with tissue degeneration/destruction.

Priority: EP20050025261 Applic. Date: 2005-11-18; WO2006EP11074 Applic. Date: 2006-11-17

Inventor: POHL JENS [DE]; PLOGER FRANK [DE]; KRUSE MICHAEL [DE]


Application No.: US20080318862A1  Published: 25/Dec/2008

Title: CROSSLINKABLE POLYMERIC MATERIALS AND THEIR APPLICATIONS

Applicant/Assignee: A ENTERPRISES, INC

Application No.: 12/119489   Filing Date: 12/May/2008

Abstract:

The present invention relates to a novel composition for dental, orthopedic and drug delivery purpose. Specifically, it relates to composition comprising an admixture of a resorbable bone substitute and a crosslinkable prepolymer. It also relates to the composition formed by crosslinking the admixture.

Priority: US2004-789442 Applic. Date: 2004-02-26; US20030450538P Applic. Date: 2003-02-27

Inventor: ASHMAN ARTHUR [US]; SHASTRI V PRASAD [US]


Application No.: US20080319100A1  Published: 25/Dec/2008

Title: Dental Impression Masses, Hardened Products Produced from them, and Use of Surfactants for the Production of Dental Impression Masses

Applicant/Assignee: KETTENBACH GMBH & CO. KG KETTENBACH GMBH & CO., KG

Application No.: 12/087319   Filing Date: 05/Jan/2007

Abstract:

Dental impression masses are described, which contain selected curable polymer systems and a mixture of a silicon-containing non-ionic surfactant that has at least one (poly)alkylene oxide radical and a molecular mass of less than 6000 g/mol, and of a non-ionic fluorosurfactant containing at least one partially fluoridated or perfluoridated hydrocarbon radical that is connected with a (poly)alkylene oxide radical, a hydrocarbon radical, an aliphatic polyhydroxy radical, or heterocyclic radical that contains nitrogen, by way of an oxygen atom, an amino group, a keto group, a carboxylic acid ester group, a phosphoric acid ester group, a carboxylic acid amide group and/or a phosphoric acid amide group, or of a non-ionic fluorosurfactant that has at least one partially fluoridated or perfluoridated hydrocarbon radical and at least one amino oxide radical.

These dental impression masses flow extremely well onto the damp tooth under practical conditions, and an extremely detail-accurate impression forms during the processing time.

Priority: DE200610001126 Applic. Date: 2006-01-09; WO2007EP00066 Applic. Date: 2007-01-05

Inventor: BUBLEWITZ ALEXANDER [DE]; REBER JENS-PETER [DE]


Application No.: US20080319102A1  Published: 25/Dec/2008

Title: Dental Composition Containing Epoxy Functional Polymerizable Compounds

Applicant/Assignee:

Application No.: 11/572051   Filing Date: 12/Jan/2007

Abstract:

The present invention relates to dental compositions comprising a halogenated epoxy functional ether derivative comprising at least one aryl alkyl ether moiety, at least one halogen atom attached to each aryl residue of the aryl alkyl ether moieties, at least two aliphatic epoxy moieties, no glycidyl ether structure, an initiator, optionally filler and optionally additive components selected from the group of modifiers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavourings.

Priority: WO2004EP07748 Applic. Date: 2004-07-14

Inventor: ECKERT ADRIAN S [DE]; BISSINGER PETER [DE]; DEDE KARSTEN [DE]; KLETTKE THOMAS [DE]; THALACKER CHRISTOPH [DE]; JACOBS DWIGHT W [US]; MADER ROGER A [US]

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LIST OF US PATENT APPLICATIONS IN ORAL CARE FORMULATIONS PUBLISHED IN 2008
This list includes Provisional Patent Applications published in the United States. The list was retrieved by using a refined search strategy on the claims section of all patent applications.
Salient search terms included oral care formulations and compositions for tooth cleaning and whitening; denture and dental prosthesis care; caries, calculus, stains and plaque prevention,
reduction and removal of plaque; dental adhesives, dental polymers, cement curing; polymer UV curing, cavity fillers, disinfectants, bleaching; oral hygiene and devices, etc.
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