US Patents and in Nano-technology for Skin Care
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US PATENTS IN NANO-TECHNOLOGY FOR SKIN CARE GRANTED SINCE 1980

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US PATENTS IN NANOTECHNOLOGY FOR SKIN CARE GRANTED FROM 1980 TO 2009



Patent No.: US 4195641 A Issued: 1980-04-01

Title: Spectroscopic analysis of chemical substances

Applicant: BURTON LARRY W; JOINES WILLIAM T; RAFAL MARC D; SPOCK ALEXANDER

Application No.: US1977-0860983 Applic. Date: 1977-12- 15

Abstract: An intense electric field is employed as the external source of energy in carrying to a spectroscopic analysis of a chemical composition. The substance to be analyzed is placed between an insulated conductive electrode and a ground reference. A high voltage is then applied to the electrode to generate an electric field of a predetermined intensity within the test sample. As a result of the energy absorbed, the constituents of the sample are caused to release their characteristic spectral emissions. These emissions are optically filtered to isolate the wavelength of interest which is passed to a light detector and registered on a photon counting system. The procedure is especially and uniquely applicable for conducting an in situ chemical analysis of human sweat, thus offering a valuable aid in the diagnosis of various medical abnormalities.

Priority: US1977-0860983 Applic. Date: 1977-12-15

Inventor: BURTON LARRY W (US); JOINES WILLIAM T (US); RAFAL MARC D (US); SPOCK ALEXANDER (US)


Patent No.: US 4203848 A Issued: 1980-05-20

Title: Processes of making a porous membrane material from polyvinylidene fluoride, and products

Applicant: MILLIPORE CORP

Application No.: US1977-0800574 Applic. Date: 1977-05- 25

Abstract: Covers processes for making microporous membranes and molecular filtration membranes from vinylidene fluoride polymers, and the products so produced. A continuous version of the process consists of applying a layer of a solution of a polyvinylidene fluoride polymer to a rigidly supported surface of a backing belt to form a film, then passing the belt through a formation bath, in which the membrane is formed. To form the polymer solution, the polymer is dissolved in a liquid vehicle that will dissolve up to about 25% by weight of the polymer at a temperature of at least 50 DEG C. but that dissolves substantially less of the polymer at about 20 DEG C. (room temperature). The polymer solution is formed at 50 DEG C. or higher, and the formation bath is maintained at about room temperature.; The formation bath is a mixture of the liquid vehicle solvent with a second liquid that is miscible with the solvent but that is not itself a solvent for the polymer. The film is maintained immersed in the formation bath until it has been converted to a porous membrane whose pore structure is essentially fully formed, by leaching of the solvent from the film and its replacement with the non- solvent liquid. Thereafter the residual solvent is extracted from the porous membrane, and after separation of the membrane from the backing belt, the membrane is dried. The preferred solvent - non- solvent system for the formation bath is acetone-water. A preferred formation bath composition is from about 70% to about 80% acetone by volume.

Priority: US1977-0800574 Applic. Date: 1977-05- 25

Inventor: GRANDINE JOSEPH D II (US)


Patent No.: US 4335465 A Issued: 1982-06- 15

Title: Method of producing an accellerating electrons and ions under application of voltage and arrangements connected therewith

Applicant: CHRISTIANSEN JENS; SCHULTHEISS CHRISTOPH

Application No.: US1979-0008162 Applic. Date: 1979-01- 31

Abstract: An electron and ion accelerator includes plural spaced electrodes which are apertured to define a gas discharge path and supported at their peripheries by insulative means. A gas supply provides low pressure gas capable of producing electrons and ions in the gas discharge path. A voltage applied between the at least two electrodes establishes an electrical potential between them such that a spark-like gas discharge occurs along the gas discharge path. The current density obtainable in the low pressure gas is substantially higher than the density of an electron or ion flow in a vacuum.

Priority: DE1978-2804393 Applic. Date: 1978-02-02

Inventor: CHRISTIANSEN JENS; SCHULTHEISS CHRISTOPH


Patent No.: US 4398541 A Issued: 1983-08- 16

Title: Method and apparatus for measuring moisture content of skin

Applicant: XIENTA INC (US)

Application No.: US1978-0909664 Applic. Date: 1978-05-25

Abstract: There are disclosed a method and an apparatus for measuring moisture content of skin. The skin surface is illuminated with polarized light incident at the Brewster angle. The degree of polarization of the light refracted within the skin and reflected out is measured. The measurement is a function of the refractive index of the skin which, in turn, is a function of the moisture content. To avoid measurement variations due to such things as skin color, output readings are in the form of a ratio of the reflected polarized light intensity to the reflected total light intensity.

Priority: US1978-0909664 Applic. Date: 1978-05-25

Inventor: PUGLIESE PETER (US)


Patent No.: US 4401649 A Issued: 1983-08-30

Title: Sunscreen method

Applicant: POLAROID CORP (US)

Application No.: US1981-0284624 Applic. Date: 1981-07- 20

Abstract: Sunscreen compositions are described which comprise a pharmaceutically acceptable carrier having incorporated therein, in an amount effective to provide protection against the harmful effects of ultraviolet radiation, a compound of the formula [IMAGE] wherein X is an alkylene group containing 1 to 7 carbon atoms and the amino group of unspecified position is substituted meta or para to the ester group.

Priority: US1981-0284624 Applic. Date: 1981-07- 20

Inventor: GREEN MILTON (US)


Patent No.: US 4421739 A Issued: 1983-12- 20

Title: Benzylidene-camphors, processes for their preparation and cosmetic compositions containing them

Applicant: OREAL (FR)

Application No.: US1978-0886560 Applic. Date: 1978-03-14

Abstract: The invention provides compounds which are particularly valuable for use as the active ingredient in sun tan lotions and creams and the like. These compounds have the general formula: [IMAGE] in which Y denotes hydrogen or the radical SO3H or a salt thereof with an organic or inorganic base, and Z denotes the radical -CH2Br or -CHBrBr or a radical Z' which denotes the radical -CH2I, -CH2R, -CHR'R', -CHO or -COOR'', in which R denotes -NR1R2, -N+R1R2R3, -OR4, -OCOR5, -SR6, -CN, -COOR'' or -SSO3Na, in which R1 and R2 independently denote hydrogen, C1-18 alkyl or hydroxyalkyl, or R1 and R2, together with the nitrogen atom to which they are attached, denote a heterocyclic ring, R3 denotes C1-4 alkyl or hydroxyalkyl or sulphonatopropyl, R4 denotes hydrogen, alkyl, polyoxyethylene, aryl which is optionally substituted, menthyl or dialkylaminoalkyl, R5 denotes alkyl, alkenyl,; aryl or a 5 or 6 membered heterocyclic ring which is optionally aromatic, and R6 denotes hydrogen, alkyl, carboxyalkyl, aminoalkyl, hydroxyalkyl, aryl or 3-alanyl, R' denotes -OR'4 or -SR'6, in which R'4 and R'6 are as defined under R4 and R6, respectively, except for hydrogen, polyoxyethylene, hydroxyalkyl, 3-alanyl and aryl, and R'' denotes hydrogen or alkyl, such that when R denotes N+R1R2R3, R1 and R2 are not hydrogen and either R3 denotes sulphonatopropyl, or the compound is in the form of a salt with an anion, which is SO4alkyl, SO3aryl, SO3alkyl or halogen or an inorganic or organic acid addition salt thereof when R denotes -NR1R2.

Priority: FR1977-0007720 Applic. Date: 1977-03-15; FR1977-0027343 Applic. Date: 1977-09-09

Inventor: BOUILLON CLAUDE (FR); VAYSSIE CHARLES (FR)


Patent No.: US 4463762 A Issued: 1984-08-07

Title: Apparatus for obtaining an objective determination of the rate of oxygen utilization in peripheral tissue

Applicant: INST OF APPLIED BIOLOGY SPECIA (US)

Application No.: US1980-0132994 Applic. Date: 1980-03- 24

Abstract: Apparatus employing a non-invasive method for objectively determining in vivo, the rate of oxygen utilization in peripheral tissue by spectral measuring means, containing a light source, a clamp or tourniquet for occluding a segment of blood in the tissue, means for transmitting the light through the isolated segment of blood to pick up the spectral values of the oxyhemoglobin for two selected wavelengths, wherein the rate of reduction of the oxyhemoglobin of the blood as determined at one wavelength is faster that the rate of reduction of the oxyhemoglobin at the other wavelength, means for converting the spectral values individually for the two selected wavelengths into current flow, and means for determining the time-space relationship between the changing spectral values of the two selected wavelengths, from the moment of occlusion.

Priority: US1980- 0132994 Applic. Date: 1980-03-24; US1977-0843270 Applic. Date: 1977-10-18

Inventor: RUBENS HARRY E (US)


Patent No.: US 4515774 A Issued: 1985-05-07

Title: Liquid, cinnamal dialkyl malonates as sole organic sunscreens

Applicant: DYK & COMPANY INC VAN (US)

Application No.: US1984-0621454 Applic. Date: 1984-06-18

Abstract: Non-polar cosmetic oil compositions containing a liquid cinnamal dialkyl malonate are very effective in providing broad spectrum sunscreen protection.

Priority: US1984-0621454 Applic. Date: 1984-06- 18

Inventor: CONNER DONALD E (US); KLEIN KENNETH (US)


Patent No.: US 4534976 A Issued: 1985-08- 13

Title: Method and means for repelling animals

Applicant: INT FLAVORS & FRAGRANCES INC (US)

Application No.: US1983-0519182 Applic. Date: 1983-08- 01

Abstract: Described for use as a key ingredient in an animal control composition and more particularly in an animal repellent composition, is the genus of steroids defined according to the structure: [IMAGE] wherein X completes a substituted cyclopentyl moiety and is one of the moieties: [IMAGE] [IMAGE] [IMAGE] [IMAGE] [IMAGE] wherein Y represents methylene, carbinol or keto; and wherein Z completes a substituted cyclohexyl moiety and is one of the moieties: hydroxycyclohexyl; ketocyclohexyl; ketocyclohexenyl; hydroxyphenyl; cyclohexenyl; or bicyclohexyl and wherein the dashed line represents a carbon-carbon single bond or a carbon-carbon double bond. Also described are animal control articles consisting of one or more members of the above mentioned steroid genus and imbedded in a compatible polymer.

Priority: US1983-0519182 Applic. Date: 1983-08-01; NO1981-0002613 Applic. Date: 1981-07-31

Inventor: HANSEN HELGE (NO); NYSTROM BORJE (NO); TORNENG EYVIN (NO)


Patent No.: US 4597961 A Issued: 1986 -07-01

Title: Transcutaneous application of nicotine

Applicant: ETSCORN FRANK T

Application No.: US1985-0694047 Applic. Date: 1985-01- 23

Abstract: Percutaneous administration of nicotine in a dose approximating the dose delivered by a variety of nicotine-containing products, such as cigarettes, cigars, snuff and chewing tobacco, is carried out using an occlusive pad. The nicotine is delivered so as to mimic the pharmacological effects of nicotine provided by the conventional use of tobacco, and a therapeutic function is achieved by reducing or eliminating the need for the tobacco product. A suitable transdermal application pad comprises a reservoir for liquid nicotine base to be affixed to the skin in a variety of places. Due to the high lipid solubility and resultant high skin permeability of nicotine, vehicles or solvents are not generally needed to enhance dermal absorption.

Priority: US1985-0694047 Applic. Date: 1985-01-23; EP1986-0401095 Applic. Date: 1986-05-23

Inventor: ETSCORN FRANK T (US)


Patent No.: US 4613499 A Issued: 1986-09-23

Title: Substituted cinnamal dialkyl malonates in sunscreening, skin care compositions

Applicant: DYK & COMPANY INC VAN (US)

Application No.: US1985-0747241 Applic. Date: 1985-06-21

Abstract: Compositions containing an organic sunscreen and particular substituted cinnamal dialkyl malonate adjuvants therefor are very effective in providing broad spectrum sunscreen protection and skin care.

Priority: US1985-0747241 Applic. Date: 1985-06-21; US1982-0404964 Applic. Date: 1982-08- 03

Inventor: CONNER DONALD E (US)


Patent No.: US 4623793 A Issued: 1986-11- 18

Title: Device and method for determining skin type

Applicant: REVLON (US)

Application No.: US1983-0472547 Applic. Date: 1983-03- 07

Abstract: A battery-powered device and method for determining the skin type of a living subject is disclosed in which an oil sample carried by a probe is subjected to the impingement of an essentially monochromatic light source of predetermined wavelength. The amount of light passing through the oil sample is detected and an output voltage proportional thereto is produced. This output voltage is amplified, integrated and then drives an LED display which indicates the skin type of the subject. Calibration means and a method for calibrating the device utilizing both an oil-free and oily probe are disclosed. The calibration means include both means for adjusting the bandwidth of the output of the amplifying circuit and gain control means for adjusting the output voltage of the amplifying circuit.

Priority: US1983-0472547 Applic. Date: 1983-03-07

Inventor: HOFKE FRED (US); MARGOLIN IRWIN (US)


Patent No.: US 4634422 A Issued: 1987-01-06

Title: Percutaneous access device and method for implanting same

Applicant: KANTROWITZ ADRIAN (US); FREED PAUL S (US); VAUGHAN FRIZELL L (US); BERNSTEIN ISADORE A (US); GRAY ROBERT H (US)

Application No.: US1984- 0615883 Applic. Date: 1984-05-31

Abstract: A percutaneous access device (PAD) is provided with a sleeve or separable member which may be detached from the device to enable the culturing of a multilayer fibroblast coating on the member in a stable and undisturbed environment. The member is constructed so that when it is assembled into the device and the device is implanted in a patient, the cultured coating of the member is exposed to the patient's dermis whose fibroblasts will, after a relatively short healing period, merge with the fibroblasts of the coating to form a barrier layer interlocked with the member to prevent epidermal ingrowth or marsupialization of the implanted device. Implantation techniques for further facilitating the formation of the dermal barrier are also disclosed.

Priority: US1984-0615883 Applic. Date: 1984-05-31

Inventor: KANTROWITZ ADRIAN (US); FREED PAUL S (US); VAUGHAN FRIZELL L (US); BERNSTEIN ISADORE A (US); GRAY ROBERT H (US)


Patent No.: US 4672973 A Issued: 1987-06-16

Title: Device and method for determining skin type

Applicant: REVLON (US)

Application No.: US1985-0767078 Applic. Date: 1985-08-20

Abstract: A battery-operated device and method for determining the skin type of a living subject is disclosed in which an oil sample carried by a probe is subjected to the impingement of an essentially monochromatic light source of predetermined wavelength. The amount of light passing through the oil sample is detected and an output current proportional thereto is produced. This output current is amplified and drives a meter which displays the skin type of the subject. Calibration means and a method for calibrating the meter utilizing an oil-free probe are disclosed, as well as a means for adjusting the bandwidth of the output of the amplifier to coincide with the meter.

Priority: US1985-0767078 Applic. Date: 1985-08-20; US1983-0472781 Applic. Date: 1983-03-03

Inventor: HOFKE FRED (US)


Patent No.: US 4678292 A Issued: 1987-07- 07

Title: Curved structure and method for making same

Applicant: RCA CORP (US)

Application No.: US1984-0625025 Applic. Date: 1984-06- 27

Abstract: A plurality of thin flexible sheet ribs are secured to thin flexible sheet stringer members to form a distortable frame structure. One edge of the ribs lie in a curved surface such as a parabolic cylindrical surface. A thin sheet of boron-silicate glass, preferably formed with a second surface mirror, is annealed and then bent at room temperature to abut the edges of the ribs lying in the curved surface and is retained in place by ribs at opposite edges of the sheet. The inherent strength of the glass under stress, when bent, provides structural rigidity to the combined elements.

Priority: US1984-0625025 Applic. Date: 1984-06-27; US1981-0259515 Applic. Date: 1981-05-01

Inventor: MIYATANI KAZUO (JP); SATO ISAO (JP)


Patent No.: US 4725590 A Issued: 1988-02- 16

Title: Method of relieving pain and inflammatory conditions employing substituted salicylamides

Applicant: LEVER BROTHERS LTD (US)

Application No.: US1985- 0774617 Applic. Date: 1985-09-10

Abstract: A topically and systemically administered anti-inflammatory composition for human and for veterinary consumption which comprises compounds of the general formula: [IMAGE] wherein R1, R2 and R3 are defined hydrocarbon attachments and Y is -OH or a phenolic ester group derived from the reaction of such -OH group with a carboxylic acid halide or anhyride. In typical compounds covered by said general formula (a) R1 is H, R2 is 5,n- octanoyl, Y is hydroxy and R3 is p-trifluoromethylphenyl; (b) R1 is H, R2 is 5,n-decanoyl, Y is hydroxy and R3 is benzothiazol-2-yl and (c) R1 is H, R2 is 5,n-decanoyl, Y is acryloyloxy and R3 is p- nitrophenyl.; The resulting compositions take the form of ointments, solid sticks, tablets, capsules, injectable solutions and suspensions, ear drops, eye drops, nose drops, douches, suppositories, enemas, liniments, gels, lotions, shampoos, soaps, creams, solutions, aerosols, pads, plasters, bandages, dressings and catamenial and non-cateminal tampons. The compositions are useful in relieving pain or inflammation as well as microbial infections in mammals when applied topically to the skin or affected organs or when administered systemically.

Priority: US1985-0774617 Applic. Date: 1985-09- 10; US1983-0525916 Applic. Date: 1983-08-24

Inventor: RITCHEY THOMAS W (US)


Patent No.: US 4774039 A Issued: 1988 -09-27

Title: Dispersing casting of integral skinned highly asymmetric polymer membranes

Applicant: BRUNSWICK CORP (US)

Application No.: US1986-0932372 Applic. Date: 1986-11-19

Abstract: There is disclosed, in one aspect, an improved highly asymmetric membrane comprising a skin and a porous asymmetric support. The skin contains pores which have an mean pore diameter of from about 0.005 to about 3.0 microns and the asymmetric support comprises a reticulated structure which contains pores which have pore diameters of from about 10 to about 20,000 times as large as the pore diameter of the pores of the skin. The membrane has a bulk porosity greater than about 70%. In another aspect, there is disclosed a process for preparing these membranes. This process comprises casting a polymer dope while the dope is in an unstable liquid dispersion condition. The concentration of polymer in the polymer dope should be high enough to produce a coherent membrane yet low enough to form a substantially all-reticulated structure within the asymmetric support.; The membranes are characterized by high flow rates, excellent retention properties, and improved resistance to fouling.

Priority: US1986-0932372 Applic. Date: 1986-11-19; US1980-0130566 Applic. Date: 1980-03-14; US1981-0291927 Applic. Date: 1981-08- 11

Inventor: WRASIDLO WOLFGANG J (US)


Patent No.: US 4777041 A Issued: 1988-10- 11

Title: Wrinkle treatment formulation

Applicant: RITZ GROUP LTD CHARLES (US)

Application No.: US1986-0894141 Applic. Date: 1986-08- 07

Abstract: A wrinkle treatment formulation is provided which is in the form of a gel formed of at least 95% by weight of a gelable hydrophilic polyurethane polymer base and a precipitated silica thickener gelling agent. Upon brushing the above-described gel formulation on wrinkled skin, the gel fills up wrinkles and dries to impart to so-treated skin a smooth substantially wrinkle-free appearance.

Priority: US1986-0894141 Applic. Date: 1986-08-07

Inventor: MERCADO CLARA (US)


Patent No.: US 4810246 A Issued: 1989-03-07

Title: Disposable cell culture chamber with remote access

Applicant: L VAD TECHNOLOGY INC (US)

Application No.: US1987-0116311 Applic. Date: 1987-11-04

Abstract: A combination is provided of a percutaneous lead designed for implantation in the human body, which lead has a surface which is adapted to pass through and be exposed to the dermis of a patient when the device is implanted. Said surface is adapted to receive the growth of a cultured autogenous fibroblast coating on an etched, nanoporous surface. A liquid tight sealed removable, disposable chamber encloses said surface, said chamber being provided with openings for introduction therein of finely divided living dermal tissue suspended in a liquid carrier, thus providing a means for formation of the cultured surfaces which can be easily handled. The disposable chamber is removed and discarded at the time of surgery.

Priority: US1987- 0116311 Applic. Date: 1987-11-04

Inventor: FRISCH ELDON E (US); KANTROWITZ ADRIAN (US); FREED PAUL S (US)


Patent No.: US 4820508 A Issued: 1989-04-11

Title: Skin protective composition

Applicant: NEUTROGENA CORP (US)

Application No.: US1987-0065348 Applic. Date: 1987-06-23

Abstract: A skin protective composition for topical application to mammalian skin for protection from infrared radiation containing titanium dioxide and mica or coated mica as its principal active reagents.

Priority: US1987-0065348 Applic. Date: 1987-06-23

Inventor: WORTZMAN MITCHELL S (US)


Patent No.: US 4822600 A Issued: 1989-04- 18

Title: Infrared blocker

Applicant: NEUTROGENA CORP (US)

Application No.: US1987-0054438 Applic. Date: 1987-05-27

Abstract: A transparent or translucent composition for topical application to mammalian skin for protection from infrared rays comprising fumed silica admixed with conventional UV blockers as its principal active constituents.

Priority: US1987-0054438 Applic. Date: 1987-05-27

Inventor: WORTZMAN MITCHELL S (US)


Patent No.: US 4840179 A Issued: 1989-06-20

Title: Combined sensor for the transcutaneous measurement of oxygen and carbon dioxide in the blood

Applicant: HELLIGE GMBH (DE)

Application No.: US1987-0121713 Applic. Date: 1987-11-17

Abstract: The combined sensor with a thermostatted heating device (7, 23) for the simultaneous and continuous transcutaneous measurement of oxygen (O2) and of carbon dioxide (CO2) in the blood contains a measuring device (1) for the partial pressure of CO2 (pCO2), in which there is pure optical/spectrometric operation or which operates on the principle of pH measurement in an electrolyte (8), and which is separated from the measuring site on the skin by a membrane (13) which is permeable to both CO2 and light, and contains another measuring device (24, 25, 26) for the spectrometric measurement of the blood oxygen saturation (sO2).; The advantage over a known pO2/pCO2 combined sensor is that the combined sensor according to the invention can be operated at a low operating temperature of, for example, 42 DEG C. or less, so that continuous measurement for 24 hours, for example, is possible without resiting or recalibrating the sensor, and thus it is simple to use in the domestic milieu.

Priority: EP1986-0115941 Applic. Date: 1986-11-17

Inventor: ULLRICH GEORG J (DE)


Patent No.: US 4874361 A Issued: 1989-10- 17

Title: Method for healing damaged skin

Applicant: OBAGI ZEIN E (US)

Application No.: US1986-0947085 Applic. Date: 1986-12-29

Abstract: A composition and method of using the same for treating human skin of all races for a wide variety of skin ailments, including acne, blemishing, aging, sun damage and cancerous lesions, and other problems associated with skin disorders. The method comprises applying to a region of damaged skin a composition of trichloroacetic acid, a surfactant having cell growth stimulatory properties, and an emulsifier. The ratio of the various ingredients can be varied to effect optimal treatment for a particular type of skin. For treatment of certain disorders, the effect of the composition is enhanced if the skin is irradiated with a suitable light source. The latter stimulates even skin regeneration. Several days after treatment, the damaged area peels off, and a new layer of vibrant, evenly colored, healthy skin is apparent.; The procedure can be repeated without adverse effects, although generally a single application is sufficient.

Priority: US1986-0947085 Applic. Date: 1986-12- 29

Inventor: OBAGI ZEIN E (US)


Patent No.: US 4878891 A Issued: 1989-11- 07

Title: Method for eradicating infectious biological contaminants in body tissues

Applicant: BAYLOR RES FOUND (US)

Application No.: US1987-0067237 Applic. Date: 1987-06-25

Abstract: A method for externally eradicating infectious pathogenic contaminants, such as enveloped viruses, bacteria, trypanosomal and malarial parasites, present in body tissues, such as blood, blood components, semen, skin, and cornea, before the treated body tisues are introduced into, or transplanted onto, the body of a human or an animal.; Such method includes the steps of: (1) admixing an effective, non-toxic amount of photoactive compound, whch has a selectivity for binding to the infectious pathogenic biological contaminants present therein, with the body tissues outside the body to produce a resulting body tissues; (2) passing the resulting body tissues through an irradiating cell assembly, and (3) irradiating the resulting body tissues in the irradiating path of the cell assembly for an effective period of time with an effective level of radiation such that the radiation penetrates the resulting body tissues and eradicates the photoactive- compound-bound contaminants present in the resulting body tissues and produces a decontaminated body tissue suitable for introducing into, or transplanting onto, the body of a human or animal.

Priority: US1987-0067237 Applic. Date: 1987-06-25

Inventor: JUDY MILLARD M (US); MATTHEWS JAMES L (US); NEWMAN JOSEPH T (US); SOGANDARES-BERNAL FRANKLIN (US)


Patent No.: US 4894222 A Issued: 1990 -01-16

Title: Waterproof sunscreen

Applicant: NEUTROGENA CORP (US)

Application No.: US1988-0177090 Applic. Date: 1988-04-04

Priority: US1988-0177090 Applic. Date: 1988-04-04; CA1989-0611656 Applic. Date: 1989-09-15; JP1989-0243580 Applic. Date: 1989-09-21

Inventor: MATRAVERS PETER (US)


Patent No.: US 4896314 A Issued: 1990-01- 23

Title: Bump-forming media including thin intermediate reflective layer and methods for writing, reading, and erasing same

Applicant: OPTICAL DATA INC (US)

Application No.: US1988-0183719 Applic. Date: 1988-04-19

Priority: US1988-0183719 Applic. Date: 1988-04-19

Inventor: SKIENS W EUGENE (US); LIND MICHAEL A (US); HARTMAN JOHN S (US); SWANSON JOHN W (US); IWAMOTO NANCY E (US)


Patent No.: US 4906457 A Issued: 1990-03- 06

Title: Compositions and methods for reducing the risk of sunlight and ultraviolet induced skin cancer

Applicant: UNIV WASHINGTON (US)

Application No.: US1988 -0241039 Applic. Date: 1988-09-06

Abstract: Compositions and methods for reducing the risk of skin cancer. The novel compositions include at least one effective protease inhibitor. Preferred protease inhibitors include serine protease inhibitors and metallo- protease inhibitors. The protease inhibitors are preferably included in concentrations ranging from approximately 10 picograms to 10 milligrams per milliliter of the skin-applicable topical mixtures. The topical mixtures preferably include a suitable topical vehicle such as a cream, lotion, or ointment. One class of anti-carcinogenic skin treatment compositions of this invention preferably includes the desired protease inhibitors in combination with a suitable sunscreen agent or agents, such as para-amino benzoic acid, to provide particularly advantageous compositions for reducing the risk of sunlight-induced skin cancer.

Priority: US1988-0241039 Applic. Date: 1988-09-06

Inventor: RYAN CLARENCE A (US)


Patent No.: US 4920989 A Issued: 1990-05-01

Title: Method and apparatus for aiding in the reduction of incidence of tobacco smoking

Applicant: UNIV CALIFORNIA (US)

Application No.: US1988-0157536 Applic. Date: 1988-02-19

Abstract: A method of aiding in the reduction of incidence of tobacco smoking. The method comprises applying a patch containing nicotine to the skin of a person with whom smoking reduction is desired and allowing the nicotine to transdermally migrate into the person's bloodstream to achieve a desired systemic nicotine level. The method also comprises the simultaneous administration of a nicotine containing aerosol spray to the oral cavity of the user in order to provide the desired sensations in the respiratory tract to which the user is accustomed from normal tobacco smoke. A combination of the spray and transdermal patch is also provided such that an occlusive patch is applied to the skin of the person with whom smoking reduction is desired and the nicotine containing aerosol spray is delivered to the oral cavity simultaneously with the application of the nicotine from the patch.

Priority: US1988-0157536 Applic. Date: 1988-02-19; US1985-0727525 Applic. Date: 1985-04-25

Inventor: ROSE JED E (US); JARVIK MURRAY E (US); ROSE KARCE D (US)


Patent No.: US 5008294 A Issued: 1991-04-16

Title: Methods of treating tumors with compositions of catecholic butanes

Applicant: CHEMEX PHARMACEUTICALS INC (US)

Application No.: US1987-0057481 Applic. Date: 1987-06-03

Abstract: The invention relates to methods useful in the treatment of benign, premalignant and malignant solid tumors, especially those of the skin comprising methods for the administration of pharmacologically active compositions containing catecholic butanes. The invention also relates to methods of preventing the occurence of tumors, and the use of catecholic butanes as a sunscreening agent. The preferred catecholic butane is nordihydroguaiaretic acid. The preferred methods of application of the compositions containing catecholic butanes are by topical application and intratumor injection.

Priority: US1987-0057481 Applic. Date: 1987-06-03; US1987-0052120 Applic. Date: 1987-05-04; US1985-0699923 Applic. Date: 1985-02-11

Inventor: NEISS EDWARD S (US); ALLEN LARRY M (US)


Patent No.: US 5008548 A Issued: 1991-04-16

Title: Personal UV radiometer

Applicant: GAT NAHUM (US)

Application No.: US1989-0388115 Applic. Date: 1989-08- 01

Abstract: A miniaturized portable battery operated combined power/energy radiometer appropriate for personal use provides a convenient means for determination of the direction of maximum radiant UV power and the measurement of the total energy over time or dosage. The radiometer possesses particular usefulness for sunbathers, walkers, and other persons who are exposed to ambient radiation. Suitably the radiometer includes means for attachment to an article of clothing and/or a positionable stand.

Priority: US1989-0388115 Applic. Date: 1989-08-01

Inventor: GAT NAHUM (US)


Patent No.: US 5009969 A Issued: 1991-04-23

Title: Dual action sunscreen composition

Applicant: HI TEK POLYMERS INC (US)

Application No.: US1989- 0357985 Applic. Date: 1989-05-26

Abstract: Dual action sunscreen compositions capable of both moisturizing the skin and protecting it from sunburn are made from a cationic guar, a cationic acrylic polymer and an ultraviolet absorbing sunscreening agent.

Priority: US1989-0357985 Applic. Date: 1989-05-26

Inventor: MILLER GARY A (US)


Patent No.: US 5014713 A Issued: 1991-05- 14

Title: Method and apparatus for measuring thickness of fat using infrared light

Applicant: TARRIS ENTERPRISES INC (US)

Application No.: US1989-0446054 Applic. Date: 1989-12-05

Abstract: A body fat thickness measuring device comprising a pair of infrared emitting diodes, one emitting a steady, low-intensity light, and the other emitting periodic, high-intensity pulses of light, to be placed against the skin where the fat is to be measured. The device contains an array of detectors in the form of infrared-sensitive photo-transistors which are placed against the skin in predetermined locations near the two diodes, yet shielded from ambient light. The detector array provides signals proportional to the amount of infrared light detected, and these signals are summed and amplified, forming a composite signal. The amplitude of this composite signal, which is indicative of the thickness of the layer of fat, is displayed on a digital readout device.

Priority: US1989-0446054 Applic. Date: 1989-12-05

Inventor: ROPER ALAN (US); JOHNSON KEITH O (US)


Patent No.: US 5016652 A Issued: 1991-05-21

Title: Method and apparatus for aiding in the reduction of incidence of tobacco smoking

Applicant: UNIV CALIFORNIA (US)

Application No.: US1988-0157627 Applic. Date: 1988-02-19

Abstract: A dermally applicable patch adapted for application to the skin of the user to enable a transdermal administration to the bloodstream of a user. The patch comprises an outer layer which is impermeable to the passage of nicotine and an inner layer which may operate as a rate controlling membrane to allow the passage of nicotine into the bloodstream of a user. An outer layer and an inner layer form a nicotine receiving area for receiving the nicotine to thereby allow the same to pass through the inner layer. In a preferred embodiment, the patch is highly effective in reducing the incidence of tobacco smoking by allowing transdermal nicotine migration into the bloodstream of a user at a rate sufficient to correspond to the nicotine level in the blood achieved by smoking.

Priority: US1988- 0157627 Applic. Date: 1988-02-19; US1985-0727525 Applic. Date: 1985-04-25

Inventor: ROSE JED E (US); JARVIK MURRAY E (US)


Patent No.: US 5024236 A Issued: 1991-06-18

Title: Photoprobe assembly

Applicant: ADVANCED MEDICAL TECHNOLOGY IN (US)

Application No.: US1988-0253488 Applic. Date: 1988-10-05

Abstract: A relatively compact easily portable photoprobe assembly is disclosed which includes an electric probe for locating acupuncture points and a light emitting diode to stimulate acupuncture points as well as injury sites. The probe and light emitting diode are controlled by an internal circuit which operates to provide a visual indication of the precise location of the desired treatment area via an impedance variation procedure as well as to pulse the light emitting diode at the desired frequency. A power supply is also contained within the assembly to render it completely portable.

Priority: US1988-0253488 Applic. Date: 1988-10 -05

Inventor: SHAPIRO RONALD S (US)


Patent No.: US 5059192 A Issued: 1991-10- 22

Title: Method of hair depilation

Applicant: ZAIAS NARDO (US)

Application No.: US1990-0513850 Applic. Date: 1990-04-24

Abstract: A method of depilation using a ruby red laser includes supplying optimum energy to a selected area of skin to cause follicular injury to the extent that depilation occurs without epidermal scaring.

Priority: US1990-0513850 Applic. Date: 1990-04-24

Inventor: ZAIAS NARDO (US)


Patent No.: US 5059499 A Issued: 1991-10-22

Title: MASTER HOLOGRAM AND MICROPATTERN REPLICATION METHOD

Applicant: TEITEL MICHAEL (US)

Application No.: US1988-0202579 Applic. Date: 1988-06-03

Abstract: A hologram is directly recorded in a sensitized metal substrate. The hologram may be an amplitude hologram, or may be treated to produce a phase relief hologram which may be stamped into a plastic material for reproduction, be archivally stored, or used as a master for electroforming a second durable surface relief hologram for use as an embossing master. A suitable material is prepared from a polished silver plate exposed to halogen vapors. After exposure, the plate is developed and fixed, and the surface is differentially etched to form a surface relief suitable for hologram embossing. Daguerreotype processes are modified to make surface amplitude holograms and phase holograms. By etching through a metal film a semiconductor mask is obtained. By depositing a silver film directly on a wafer, masks are made with very high feature definition.

Priority: US1988-0202579 Applic. Date: 1988-06-03

Inventor: TEITEL MICHAEL (US)


Patent No.: US 5059659 A Issued: 1991-10-22

Title: Surface treatments to impart hydrophilicity

Applicant: GREGOR HARRY P (US)

Application No.: US1991- 0635421 Applic. Date: 1991-01-03

Abstract: Water insoluble polymers are treated to place on their exposed surfaces the pendant alkyl imidocarbonyl (amide) groups to impart a high degree of hydrophilicity to that surface. Nitrile-containing polymers or copolymers in the form of insoluble films, filters or membranes are treated to convert a substantial fraction of the surface nitrile groups into the corresponding amide by the use of hydrogen peroxide or concentrated acids. The surface is rendered hydrophilic and resistant to fouling to the extent that even proteins are not denatured thereupon. The surface may also be converted to substituted amides by subsequent reactions to impart to it other functionalities or to serve as the basis for coupling reactions.; Other polymers capable of surface treatment to produce pendant amidocarbonyl groups include ones containing pendant esters which on cleavage of the oxygen-carbon bond give pendant alcohol groups. These are converted by cyanoethylation to form the pendant nitrile groups which can be converted to the amide. Other polymers which on hydrolysis give pendant carboxylic acids can be treated with ammonia to also produce pendant amide groups.

Priority: US1991-0635421 Applic. Date: 1991-01-03; US1987-0055667 Applic. Date: 1987-05-29

Inventor: GREGOR HARRY P (US); BURSHTEYN ALEXANDER (US); HODGINS LEONARD T (US); KASSOTIS JOHN (US); SAMUELSON EDGAR (US)


Patent No.: US 5077476 A Issued: 1991-12- 31

Title: Instrument for non-invasive measurement of blood glucose

Applicant: FUTREX INC (US)

Application No.: US1990-0565302 Applic. Date: 1990-08-10

Abstract: Near-infrared quantitative analysis instruments non-invasively measure blood glucose by analyzing near-infrared energy following interactance with venous or arterial blood, or transmission through a blood containing body part. A replaceable cartridge stores data unique to an individual patient/user. The analysis instruments are accurate and readily lend themselves to at-home testing by diabetics.

Priority: US1990-0565302 Applic. Date: 1990- 08-10; US1990-0544580 Applic. Date: 1990-06-27

Inventor: ROSENTHAL ROBERT D (US)


Patent No.: US 5089701 A Issued: 1992 -02-18

Title: Nondestructive measurement of soluble solids in fruits having a rind or skin

Applicant: US AGRICULTURE (US)

Application No.: US1990-0563170 Applic. Date: 1990-08-06

Abstract: The instant invention is drawn to efficient and nondestructive measurement of soluble solids in fruits having a rind or skin, utilizing: infrared radiation source means for providing a beam or near infrared radiation of sufficient intensity to penetrate the fruit, intensity measurement means for measuring the intensity of radiation exiting the fruit, correlating means for correlating the measurements of intensities of the exiting radiation: wherein the near infrared radiation source means and the intensity measurement means are positioned such that when a fruit is positioned within the device, the distance measured along the rind or skin of the fruit between (1) where the center of the beam intersects the rind/skin, and (2) a point on the rind/skin where the center of the field of detection intersects the rind/skin is at least about 8 cm.

Priority: US1990-0563170 Applic. Date: 1990-08-06

Inventor: DULL GERALD G (US); LEFFLER RICHARD G (US); BIRTH GERALD S (US)


Patent No.: US 5093107 A Issued: 1992-03- 03

Title: Water resistant sunscreen compositions and methods of using same

Applicant: NEUTROGENA CORP (US)

Application No.: US1989-0441282 Applic. Date: 1989-11-27

Abstract: A skin protective sunscreen composition exhibiting enhanced water repellency and conditioning effects comprising ultraviolet blockers, aliphatic waxes and hydrophobic silicones disposed in a pharmacologically acceptable water-free carrier. The composition when used in accordance herewith is useful to protect mammals from solar radiation.

Priority: US1989-0441282 Applic. Date: 1989-11-27; US1988-0245660 Applic. Date: 1988-09-16

Inventor: MATRAVERS PETER (US)


Patent No.: US 5095619 A Issued: 1992-03- 17

Title: SHAVING SYSTEM

Applicant: GILLETTE CO (US)

Application No.: US1990-0589674 Applic. Date: 1990-09-28

Abstract: A shaving unit that comprises at least one blade and a shaving composite has a surface for engaging the user's skin adjacent the blade edge. The shaving unit may be of a disposable cartridge type adapted for coupling to and uncoupling from a razor handle or may be integral with a handle so that the complete razor is discarded as a unit when the blade or blades become dulled. The blade edge (or edges) cooperate with skin engaging surfaces to define shaving geometry.; The skin-engaging surface includes a shaving aid composite that is a mixture of water insoluble matrix material, an effective amount of shaving aid material, and an effective amount of water-insoluble essential oil material, the water-insoluble essential oil material being delivered from the shaving aid composite concurrently with the delivery of the water-leachable shaving aid material during shaving to apply at least about one nanogram of the essential oil to the skin surface per square centimeter of skin surface.

Priority: US1990-0589674 Applic. Date: 1990-09-28

Inventor: DAVIS IRIS J (US); ROGERS BRIAN A (US); TSENG MINGCHIH M (US)


Patent No.: US 5117116 A Issued: 1992-05-26

Title: METHOD AND DEVICE FOR MONITORING UV RADIATION

Applicant: CYBRANDIAN LTD (IE)

Application No.: US1990-0624748 Applic. Date: 1990-12-11

Abstract: A device for monitoring UV radiation received by the skin comprises a housing. Adhesive on a face of the housing secures the device to the skin. A patch of irreversible UV sensitive material which changes color on being subjected to UV radiation is applied to an inner surface of the housing and receives UV radiation reflected from the skin. The color of the UV sensitive patch is compared with reference colors on the housing for determining the quantity of UV radiation to which the skin has been subjected.

Priority: IE1989-0003945 Applic. Date: 1989-12-11

Inventor: BANNARD JOHN E (GB); MAGUIRE DENNIS D (GB)


Patent No.: US 5153174 A Issued: 1992-10- 06

Title: POLYMER MIXTURES USEFUL IN SKIN CARE

Applicant: UNION CARBIDE CHEM PLASTIC (US); BIOMATRIX INC (US)

Application No.: US1989-0428782 Applic. Date: 1989-10-30

Abstract: Binary polymer mixtures of albumin and glycosaminoglycan and ternary polymer mixtures of polyionic polypeptide and high molecular weight and highly charged polyanions are useful for managing skin including wrinkles or other irregularities. Aqueous compositions of the ternary mixtures have pH dependent phase change properties and provide skin activated films.

Priority: US1989-0428782 Applic. Date: 1989-10-30

Inventor: BAND PHILIP A (US); BARBONE ARMINDA G (US); GODDARD ERROL D (US); LESHCHINER ADOLF (US); PARTAIN III EMMETT M (US); PAVLICHKO JOSEPH P (US)


Patent No.: US 5164185 A Issued: 1992-11- 17

Title: PHARMACEUTICAL AND COSMETIC DEPIGMENTATION COMPOSITIONS WITH A CAFFEIC ACID BASE

Applicant: OREAL (FR)

Application No.: US1991-0691045 Applic. Date: 1991-08-13

Abstract: A pharmaceutical or cosmetic depigmenting composition for application to the skin so as to improve the aesthetic appearance of the skin or to treat pathological or accidental hyperpigmentation contains caffeic acid or an ester or amide thereof in an amount effective to depigment the skin.

Priority: FR1989-0013774 Applic. Date: 1989-10- 20

PCT Info:
PCT No. PCT/FR90/00760
Sec 371 Date Aug. 13, 1991
Sec. 102(e) Date Aug. 31, 1991
PCT Filed Oct. 19, 1990
PCT Pub. No. WO91/05543
PCT Pub. Date May 2, 1991.

Inventor: CHARPIN ISABELLE (FR); CANDAU DIDIER (FR); N GUYEN QUANG L (FR); MONTASTIER CHRISTIANE (FR); MILLECAMPS FRANCOIS (FR)


Patent No.: US 5205837 A Issued: 1993-04- 27

Title: PRODUCT BASED ON INORGANIC OR ORGANIC LAMELLAR PARTICLES, CONTAINING A MELANOTIC PIGMENT, PROCESS FOR PREPARING IT AND ITS USE IN COSMETICS

Applicant: OREAL (FR)

Application No.: US1991-0731046 Applic. Date: 1991-07-16

Abstract: The invention relates to a product in powder form consisting of organic or inorganic particles having a lamellar structure, having a size of less than 50 microns and containing at least one synthetic melanotic pigment formed in situ by oxidation of an indole compound, and to its use for the protection of the human epidermis, in make-up products and for dyeing hair.

Priority: FR1990-0009053 Applic. Date: 1990-07-16

Inventor: ANDREAN HERVE (FR); JUNINO ALEX (FR)


Patent No.: US 5217455 A Issued: 1993-06- 08

Title: Laser treatment method for removing pigmentations, lesions, and abnormalities from the skin of a living human

Applicant: TAN OON T (US)

Application No.: US1991-0743797 Applic. Date: 1991-08-12

Abstract: A laser treatment method is provided which removes pigmentations, lesions, and abnormalities from the skin of a living human. The methodology comprises a carefully controlled irradiation of the chosen treatment site on the skin of a living human; avoids the creation of cosmetically disfiguring scars; and eliminates the typical hypopigmentation as well as the pitting and other changes in skin texture normally accompanying conventionally known laser treatment techniques.

Priority: US1991-0743797 Applic. Date: 1991-08-12

Inventor: TAN OON T (US)


Patent No.: US 5222495 A Issued: 1993-06- 29

Title: Non-invasive blood analysis by near infrared absorption measurements using two closely spaced wavelengths

Applicant: ANGIOMEDICS II INC (US)

Application No.: US1992-0930070 Applic. Date: 1992-08-14

Abstract: Systems and methods for non-invasive blood analysis are disclosed in which blood is illuminated at a plurality of discrete wavelengths selected from the near infrared spectrum. Measurements of the intensity of transmitted or reflected light at such wavelengths are taken, and an analysis of transmittance or reflectance ratios for various wavelengths is performed. Changes in the ratios can be correlated with specific near infrared (IR) absorption peak for the analyte which varies with concentration of the analyte (the data wavelength) and the a second (reference) wavelength being sufficiently removed from the first so that measurements of light absorption at this second wavelength are relatively insensitive to the concentration of the analyte and yet the second wavelength is sufficiently close to the first wavelength to minimize interference from scattering effects and the like.; Typically, the window bracketing these closely spaced wavelengths will be less than about 300 nm and preferably less than about 60 nm wide and, in some instances, more preferably less than about 30 nm wide.

Priority: US1990-0474344 Applic. Date: 1990-02-02; US1991-0649477 Applic. Date: 1991-02-01; US1992-0930070 Applic. Date: 1992- 08-14

Inventor: CLARKE RICHARD H (US); WANG QIAN (US)


Patent No.: US 5222496 A Issued: 1993-06- 29

Title: Infrared glucose sensor

Applicant: ANGIOMEDICS II INC (US)

Application No.: US1992-0930141 Applic. Date: 1992-08-14

Abstract: Systems and methods for non-invasive blood analysis for the presence of glucose are disclosed in which blood is illuminated at a plurality of discrete wavelengths selected from the near infrared spectrum. Measurements of the intensity of transmitted or reflected light at such wavelengths are taken, and an analysis of transmittance or reflectance ratios for various wavelengths is performed.; Changes in the ratios can be correlated with specific near infrared (IR) absorption peak for glucose at about 1600 nm +/-15 nm which varies with concentration of the analyte (the data wavelength) and the a second (reference) wavelength being sufficiently removed from the first so that measurements of light absorption at this second wavelength are relatively insensitive to the concentration of the analyte and yet the second wavelength is sufficiently close to the first wavelength to minimize interference from scattering effects and the like. Typically, the window bracketing these closely spaced wavelengths will be less than about 300 nm and preferably less than about 60 nm wide and, in some instances, more preferably less than about 30 nm wide.

Priority: US1992-0930141 Applic. Date: 1992-08-14; US1990-0474344 Applic. Date: 1990-02-02; US1991-0649477 Applic. Date: 1991-02- 01

Inventor: CLARKE RICHARD H (US); WANG QIAN (US)


Patent No.: US 5234710 A Issued: 1993-08- 10

Title: Fluorescent suntanning lamps

Applicant: GTE PROD CORP (US)

Application No.: US1991-0806680 Applic. Date: 1991-12-13

Abstract: A skin tanning fluorescent lamp having a coating of a uniform and homogeneous deflocculated physical mixture of a first and second phosphor where the first phosphor has a desired emission in the spectral region from about 320 to about 400 nanometers and the second phosphor has a desired emission in the spectral region from about 280 to about 320 nanometers, said first phosphor has a first isoelectric point at a first pH and the second phosphor has a second isoelectric point at a second pH. The first and said second pH form a range. The deflocculated coating is stabilized by deflocculating the first and second phosphors at a third pH sufficiently outside of range to produce a resulting coating consistently having desirable emission during production.

Priority: US1991-0806680 Applic. Date: 1991- 12-13

Inventor: DUTTA ARUNAVA (US); SALVI PAUL W (US)


Patent No.: US 5282467 A Issued: 1994-02- 01

Title: Non-invasive method for detecting deep venous thrombosis in the human body

Applicant: UNIV DUKE (US)

Application No.: US1992-0930002 Applic. Date: 1992-08-13

Abstract: A non-invasive method for detecting deep venous thrombosis in a human body wherein changes are effected in the amount of deoxyhemoglobin in the body limb by trapping blood in the venous system for a determinate time period and then releasing the trapped blood in the venous system. During the period that the changes in the amount of deoxyhemoglobin are effected, first and second light sources emit light of two selected wavelengths which penetrate into the deep venous system of the body limb so that the reflectance contributions can be used to measure changes in the flow and amount of deoxyhemoglobin and to thereby detect the presence or absence of deep venous thrombosis.

Priority: US1992-0930002 Applic. Date: 1992-08-13

Inventor: PIANTADOSI CLAUDE A (US); COMFORT BENJAMIN J (US); HAMPSON NEIL B (US)


Patent No.: US 5282842 A Issued: 1994-02- 01

Title: Method of inducing tanning by pulsed light and apparatus to effect same

Applicant: CHANGARIS DAVID G (US)

Application No.: US1991-0675689 Applic. Date: 1991-03-27

Abstract: A method and apparatus to effect tanning in humans. The method utilizes very short discrete pulses, with a dark period of low to zero energization between discrete pulses, of ultraviolet or visible light irradiation of selected wave length to effect the tanning. Different apparati are disclosed to carry out the invention. One type of apparatus continuously generates irradiation of the selected wave length and projects that irradiation through mechanical pathblockers to create the discrete pulses. Another type of apparatus intermittently generates irradiation in the desired discrete pulse and of the desired wave length to create the desired effect.

Priority: US1991-0675689 Applic. Date: 1991-03-27; US1992-0819116 Applic. Date: 1992-01-10

Inventor: CHANGARIS DAVID G (US)


Patent No.: US 5286629 A Issued: 1994-02- 15

Title: Method of binding a product to the membrane of a keratinocyte by means of a ligand-receptor bond, method of preparing such a product, product obtained, cosmetic or pharmaceutical composition in which it is present and its method of preparation

Applicant: DIOR CHRISTIAN PARFUMS (FR)

Application No.: US1991-0761809 Applic. Date: 1991-11- 04

Abstract: The invention relates to products which are to be bound specifically to the membrane of a keratinocyte by means of a ligand-receptor bond. These products carry at least one ligand consisting of an oside residue selected from (alpha)-L-rhamnose, (alpha)-D-galactose and (alpha)-D- galactose-6-phosphate. By virtue of this specificity, it is possible to prepare cosmetic or pharmaceutical compositions having an improved efficacy in particular, for example for regeneration of the epidermis, for the treatment of psoriasis or for renewed hair growth.;The invention concerns products for specifically fixing on the membrane of a keratinocyte by means of a ligand-receptor bond. Said products are carriers of at least one ligand consisting of an oside residue selected among alpha - L-rhamnose, alpha -D-galactose and alpha -D-galactose-6-phosphate. Because of their specific features, it is possible to prepare cosmetic or pharmaceutical compositions having, in particular, an improved efficiency for example for the regeneration of the epidermis, for the treatment of psoriasis and for hair regrowth.

Priority: FR1989-0003628 Applic. Date: 1989-03-20

PCT Info:
PCT No. PCT/FR90/00176
Sec 371 Date Nov. 4, 1991
Sec. 102(e) Date Nov. 4, 1991
PCT Filed Mar. 16, 1990
PCT Pub. No. WO90/11069
PCT Pub. Date Oct. 4, 1990.

Inventor: DENIS ALAIN (FR); KIEDA CLAUDINE (FR); MONSIGNY MICHEL (FR); PERRIER PIERRE (FR); REDZINIAK GERARD (FR)


Patent No.: US 5290273 A Issued: 1994-03-01

Title: Laser treatment method for removing pigement containing lesions from the skin of a living human

Applicant: TAN OON T (US)

Application No.: US1993-0066875 Applic. Date: 1993-05- 25

Abstract: A laser treatment method is provided which removes pigment containing lesions, both normal and abnormal medically, from the skin of a living human. The methodology comprises a carefully controlled irradiation of the chosen treatment site on the skin of a living human; avoids the creation of cosmetically disfiguring scars; and eliminates the typical hypopigmentation as well as the pitting and other changes in skin texture normally accompanying conventionally known laser treatment techniques.

Priority: US1993-0066875 Applic. Date: 1993-05-25; US1991-0743797 Applic. Date: 1991-08-12

Inventor: TAN OON T (US)


Patent No.: US 5300286 A Issued: 1994-04- 05

Title: Silicone emulsion for personal care application

Applicant: DOW CORNING (US)

Application No.: US1992-0913554 Applic. Date: 1992-07- 14

Abstract: A silicone oil-in-water emulsion composition and a method of topically treating human skin with the composition. The emulsion constitutes water, a silicone oil, and at least two nonionic emulsifiers. Each nonionic emulsifier is a solid at room temperature. One nonionic emulsifier has an HLB value less than 8.0, while the other nonionic emulsifiers has an HLB value greater than 15.0.

Priority: US1992-0913554 Applic. Date: 1992-07-14

Inventor: GEE RONALD P (US)


Patent No.: US 5304170 A Issued: 1994-04-19

Title: Method of laser-induced tissue necrosis in carotenoid- containing skin structures

Applicant: GREEN HOWARD A (US)

Application No.: US1993-0031242 Applic. Date: 1993-03-12

Abstract: A method for treating dermatological organ disorders and skin lesions in a mammal through the use of directed, pulsed laser light is described. The dermatological disorders are characterized by an increase in concentration of potential photodynamic chemical compounds like carotenoid compounds, and especially the carotenoid beta -carotene, compared to normal skin. Pulsed dye laser light of a time and duration specific for maximal absorption by a carotenoid compound like beta-carotene is directed at the regions of carotenoid accumulation within a skin disorder. Thermal coagulation necrosis of the carotenoid-accumulating skin region results, though thermal damage to surrounding tissue is limited in amount.

Priority: US1993-0031242 Applic. Date: 1993-03-12

Inventor: GREEN HOWARD A (US)


Patent No.: US 5332575 A Issued: 1994-07-26

Title: Method of targeting melanocytes with a compound containing a fucose residue

Applicant: DIOR CHRISTIAN PARFUMS (FR)

Application No.: US1992-0861780 Applic. Date: 1992-04-02

Abstract: The invention concerns a method of binding a product to the membrane of a melanocyte by means of a ligand-receptor bond, which comprises using a product consisting of a basic structure coupled to at least one ligand consisting of an oside residue accessible to the membrane receptors, said oside residue being a fucose residue, notably an Alpha-L-fucose residue.

Priority: JP1991-0283587 Applic. Date: 1991-10- 03

Inventor: REDZINIAK GERARD (FR); CERDAN DOMINIQUE (FR); KIEDA CLAUDINE (FR); MONSIGNY MICHEL (FR)


Patent No.: US 5389195 A Issued: 1995-02-14

Title: Surface modification by accelerated plasma or ions

Applicant: MINNESOTA MINING & MFG (US)

Application No.: US1991- 0665692 Applic. Date: 1991-03-07

Abstract: The present invention is a surface modification process which provides a means of rapidly heating a thin layer of a polymer surface or a thin coating of material on a coated substrate and various surfaces produced by such a process.

Priority: US1991-0665692 Applic. Date: 1991-03-07

Inventor: OUDERKIRK ANDREW J (US); DUNN DOUGLAS S (US); YU EDWARD C (US); BOHLKE SUSAN N (US)


Patent No.: US 5441726 A Issued: 1995-08- 15

Title: Topical ultra-violet radiation protectants

Applicant: SUNSMART INC (US)

Application No.: US1993-0054038 Applic. Date: 1993-04- 28

Abstract: Disclosed are compositions for application to a surface to protect the surface from ultra-violet radiation, which include zinc oxide particles having a substantially rod shape.

Priority: US1993-0054038 Applic. Date: 1993-04-28

Inventor: MITCHNICK MARK (US); MUHAMMED MAMOUN (SE)


Patent No.: US 5447716 A Issued: 1995-09-05

Title: Process for lightening the skin or treating pigmental blemishes using a composition containing benzomorpholine or 3,4-dihydro-2H- 1,4-benzoxazine derivatives

Applicant: OREAL (FR)

Application No.: US1994- 0231636 Applic. Date: 1994-04-22

Abstract: A topical process for lightening the skin or treating pigmental blemishes consisting in applying to the part of the skin to be treated a composition containing, as active compounds hydroxybenzomorpholines and derivatives thereof corresponding to the following formula: [IMAGE] (I) in which: R1 represents a hydrogen atom or an alkyl radical having from 1 to 4 carbon atoms, and R2 represents a hydroxyl radical in the 6- or 7- position.

Priority: FR1993-0004836 Applic. Date: 1993-04-23

Inventor: LAGRANGE ALAIN (FR)


Patent No.: US 5449403 A Issued: 1995-09-12

Title: Product based on colored inorganic particles including a melanin pigment, process for its preparation and its use in cosmetics

Applicant: OREAL (FR)

Application No.: US1994-0119081 Applic. Date: 1994-01-03

Abstract: A product in the form of colored inorganic particles including one or a number of melanin pigments, a process for its preparation and to its use, especially in the field of cosmetics, for make-up for the exoskeleton and/or for the skin, and in protecting human skin against UV radiation.

Priority: FR1992-0000415 Applic. Date: 1992-01- 16

Inventor: ANDREAN HERVE (FR); JUNINO ALEX (FR); ARRAUDEAU JEAN P (FR)


Patent No.: US 5449518 A Issued: 1995 -09-12

Title: Utilization of derivatives of 2,5-dihydroxyphenyl-carboxylic acids, their homologs, and their salts in preparation of a cosmetic or dermatological composition with a depigmenting action

Applicant: OREAL (FR)

Application No.: US1992-0913950 Applic. Date: 1992-07-17

Abstract: A cosmetic or dermatological composition with a depigmenting action comprises derivatives of 2,5-dihydroxyphenylcarboxylic acids, their homologs, and their salts, with the derivatives having the following structural formula: [IMAGE] (I) wherein: R1 represents OR5, or [IMAGE] R5 is a hydrogen atom, a linear or branched C1-C20 alkyl radical, a linear or branched C2-C20 alkenyl radical, or a C1-C20 alkyl radical substituted by one or more hydroxy or alkoxy groups; r' and r'', identical or different, represent a hydrogen atom, a C1-C20 alkyl radical, a C2-C6 hydroxyalkyl radical, or a C3-C6 polyhydroxyalkyl, or r' and r'' taken together, with the nitrogen atom, form a heterocycle; the number of carbon atoms in the -(CH2)n-COR1 chain is less than or equal to 21; R2 and R3, identical or different, represent a hydrogen atom, a linear or branched C1-C4 alkyl radical, or a C1-C4 alkoxy; R4 represents a hydrogen atom or a linear or branched C1-C4 alkyl radical; and n is an integer from 0 to 20, provided that, when R2 and R3 represent a hydrogen atom, n is greater than or equal to 2.

Priority: FR1991-0009029 Applic. Date: 1991-07-17

Inventor: JUNINO ALEX (FR); LAGRANGE ALAIN (FR); N GUYEN QUANG L (FR); BOURBOULON MARIE-ALIX (FR)


Patent No.: US 5451254 A Issued: 1995 -09-19

Title: Fine dispersion of melanin pigments, its preparation and its use in cosmetics

Applicant: OREAL (FR)

Application No.: US1994-0211168 Applic. Date: 1994-09-19

Abstract: The invention relates to a dispersion of melanic pigments containing in a medium selected amongst: a) the straight or branched monoalcohols comprising at least 3 carbon atoms; the straight or branched polyols comprising at least 2 carbon atoms; the saturated or unsaturated cycloaliphatic alcohols comprising at least 6 carbon atoms; the aromatic alcohols comprising at least 6 carbon atoms; the C8-C22 fatty acid esters and C1-C6 alcohol esters or the C2-C6 polyol esters; the C1-C6 aliphatic acid esters or the C8-C22 aromatic acid and fatty alcohol esters; the C8-C22 fatty acid esters and the C8-C22 fatty alcohol esters, the C6-C22 polyacid and alcohol esters, the hydroxylated fatty acid diesters; the straight or branched paraffins comprising at least 8 carbon atoms; the silicone oils; and the mixture of these different organic compounds, or b) an emulsion comprised of a liquid defined under a), non water miscible, water and an emulsifying agent, a melanic pigment in the form of particles in which at least 75% of the particles have a grain size smaller than 10 microns. The invention also relates to a method for the preparation and the utilization of such dispersion in cosmetics.

Priority: FR1991-0011514 Applic. Date: 1991-09-18; WO1992-FR00868 Applic. Date: 1992-09-16

PCT Info:
PCT No. PCT/FR92/00868
Sec 371 Date Sep. 19, 1994
Sec. 102(e) Date Sep. 19, 1994
PCT Filed Sep. 16, 1992
PCT Pub. No. WO93/05754
PCT Pub. Date Apr. 1, 1993.

Inventor: ANDREAN HERVE (FR); CANDAU DIDIER (FR); MELLUL MYRIAN (FR); PAPANTONIOU CHRISTOS (FR); PIOT BERTRAND (FR)


Patent No.: US 5468472 A Issued: 1995-11- 21

Title: Topical process for lightening the skin or treating pigmental blemishes using a composition containing 4-thioresorcin derivatives

Applicant: OREAL (FR)

Application No.: US1994-0234555 Applic. Date: 1994-04-28

Abstract: A topical process for lightening the skin or treating pigmental blemishes consisting in applying to the part of the skin to be treated a composition containing, as active compounds, 4-thioresorcin derivatives corresponding to the following formula: l radical, a C1-C6 haloalkyl radical, an aryl radical, an aralkyl radical which is unsubstituted or substituted by a lower alkyl or lower alkoxy radical or a halogen atom, the radical -CnH2n-COOR' where n is an integer between 1 and 5 and R' represents a C1-C6 alkyl radical, a morpholinoalkyl or piperidinoalkyl radical in which the alkyl radical is C1-C6, or the radical [IMAGE]

Priority: FR1993-0005452 Applic. Date: 1993-05-06

Inventor: LAGRANGE ALAIN (FR); BOROWIAK HERVE (FR)


Patent No.: US 5474762 A Issued: 1995-12- 12

Title: Sunscreen agents

Applicant: CHESEBROUGH PONDS USA (US)

Application No.: US1993-0107416 Applic. Date: 1993-08-16

Abstract: A sunscreen composition for application to human skin comprises an ultraviolet absorber which is introduced as an anion into a layered double hydroxide of the general formula [NmNn(OH)2(m+n)]y+Xx- y/xxzH2O where M is a divalent metal or lithium, N is a trivalent metal and X denotes anions present as an interlayer between layers of metal atoms joined through the OH groups. Such layered double hydroxides are, for this invention, suspended in a cosmetically acceptable vehicle.

Priority: US1993 -0107416 Applic. Date: 1993-08-16; GB1992-0003806 Applic. Date: 1992-02-21; US1993-0019721 Applic. Date: 1993-02-19

Inventor: CARR STUART W (GB); FRANKLIN KEVIN R (US); NUNN CHARLES C (US); PASTERNAK JEFFREY J (US); SCOTT IAN R (US)


Patent No.: US 5489431 A Issued: 1996-02- 06

Title: Photoprotective/cosmetic compositions comprising 2,4,6-tris[p-((2'-ethylhexyl) oxycarbonyl)anilino]-1,3,5-triazine and dioctyl malate

Applicant: OREAL (FR)

Application No.: US1995-0463503 Applic. Date: 1995-06-05

Abstract: Topically applicable sunscreen/cosmetic compositions having improved cosmetic properties and well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a photoprotecting effective amount of 2,4,6- tris[p-((2'-ethylhexyl)oxycarbonyl)anilino]-1,3,5-triazine and (ii) the oil dioctyl malate, in an amount effective to itself substantially dissolve the total amount of triazine compound (i), in a cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: FR1994-0006834 Applic. Date: 1994-06-03

Inventor: ASCIONE JEAN-MARC (FR); ALLARD DELPHINE (FR)


Patent No.: US 5538716 A Issued: 1996-07- 23

Title: Photostable cosmetic screening composition containing a UV-A screening agent and a (4-methoxybenzylidene)cyanoacetate

Applicant: OREAL (FR)

Application No.: US1993-0039047 Applic. Date: 1993-04-07

Abstract: A photostable cosmetic composition for protecting the human epidermis against UV radiation comprises, in a cosmetically acceptable carrier, from 0.5 to 5% by weight of 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane and at least 0.5% by weight of a compound of formula (I): [IMAGE] (I) where R stands for an alkyl radical, the molar ratio of the compound of formula (I) to 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane being 0.8 or over.

Priority: FR1991-0010061 Applic. Date: 1991-08-07; WO1992-FR00774 Applic. Date: 1992-08-05

PCT Info:
PCT No. PCT/FR92/00774
Sec 371 Date Apr. 7, 1993
Sec. 102 (e) Date Apr. 7, 1993
PCT Filed Aug. 5, 1992
PCT Pub. No. WO93/02659
PCT Pub. Date Feb. 18, 1993

Inventor: FORESTIER SERGE (FR); DEFLANDRE ANDRE (FR)


Patent No.: US 5554374 A Issued: 1996-09- 10

Title: Skin preparation using nanospheres

Applicant: COSMETICS DEV CO LTD (GB)

Application No.: US1994-0256634 Applic. Date: 1994-10- 17

Abstract: Preparation for skin use comprising excipients, a drug carrier encapsulating beta-carotene and a blend of UV-A and UV-B sun filters characterized in that: the drug carrier consisting of nanospheres represents 3 to 6% by weight of the preparation; the proportion of UV-B filters is greater than that of the UV-A filters; and the UV-B filters have a cinnamic structure. Application in the treatment of melanic skin stains.

Priority: WO1993-FR00006 Applic. Date: 1993-01-06; FR1992-0000619 Applic. Date: 1992-01-16

Inventor: OLIVIER-TERRAS JOSETTE (FR)


Patent No.: US 5555885 A Issued: 1996-09-17

Title: Examination of breast tissue using time-resolved spectroscopy

Applicant: NON INVASIVE TECHNOLOGY INC (US)

Application No.: US1993-0093208 Applic. Date: 1993-07-16

Abstract: A method of breast tissue examination using time-resolved spectroscopy includes the following steps. A support that includes an input port and an output port separated by a selected distance is positioned relative to the examined breast. Locations of the input and output ports are selected to examine a tissue region of the breast. Light pulses of a selected wavelength and duration less than a nanosecond are introduced into the breast tissue at the input port and detected over time at the detection port. Signals corresponding to photons of detected modified pulses are accumulated over time. Values of a scattering coefficient or an absorption coefficient of the examined breast tissue are calculated based on the shape of the modified pulses. The examined breast tissue is characterized based on the values of the scattering coefficient or the absorption coefficient.; Absorbing or fluorescing contrast agents may be introduced into the examined tissue. This method may be used in conjunction with x-ray mammography, needle localization procedure or MRI mammography.

Priority: US1993-0093208 Applic. Date: 1993-07-16; US1993- 0040168 Applic. Date: 1993-03-30; US1992-0876364 Applic. Date: 1992-04-30; US1988-0287847 Applic. Date: 1988-12-21

Inventor: CHANCE BRITTON (US)


Patent No.: US 5556617 A Issued: 1996-09- 17

Title: Composition providing a lasting cosmetic and/or pharmaceutical treatment of the upper epidermal layers by topical application on the skin

Applicant: OREAL (FR)

Application No.: US1995-0473359 Applic. Date: 1995-06-07

Abstract: A composition containing, in a suitable carrier, nanoparticles of one or more nonbiodegradable polymer(s) encapsulating an oily phase which contains at least one active oil and/or at least one carrier oil and/or at least one active ingredient in an active oil and/or a carrier oil. At least one active ingredient is chosen from those with prolonged cosmetic and/or pharmaceutical activity. The nanocapsules have a size of 100-1000 nm.

Priority: US1995-0473359 Applic. Date: 1995-06-07; WO1992- FR00824 Applic. Date: 1992-08-27; FR1991-0011344 Applic. Date: 1991-09-13; US1993-0050315 Applic. Date: 1993-05-10

Inventor: RIBIER ALAIN (FR); RICHART PASCAL (FR); HANDJANI ROSE-MARIE (FR)


Patent No.: US 5573755 A Issued: 1996-11-12

Title: Sunscreen agents

Applicant: CHESEBROUGH PONDS USA (US)

Application No.: US1994-0289042 Applic. Date: 1994-08- 11

Abstract: Hydroxy salts of formula:[M(OH)(2-a)]a+Xb-a/b.zH2Owhere M is zinc, copper or a mixture of the two and X denotes anions at least some of which display ultraviolet absorption over at least a portion of the wavelength range from 290 to 400 nanometers, their use as sunscreen agents and sunscreen compositions comprising them together with a cosmetically acceptable vehicle.

Priority: GB1993-0016901 Applic. Date: 1993-08-13

Inventor: FRANKLIN KEVIN R (GB); NUNN CHARLES C (US)


Patent No.: US 5576016 A Issued: 1996-11- 19

Title: Solid fat nanoemulsions as drug delivery vehicles

Applicant: PHARMOS CORP (US)

Application No.: US1993-0063613 Applic. Date: 1993-05- 18

Abstract: The present invention provides pharmaceutical compositions comprising nanoemulsions of particles comprising a lipid core which is in a solid or liquid crystalline phase at 25 DEG C, stabilized by at least one phospholipid envelope, for the parenteral, oral, intranasal, rectal, or topical delivery of both fat-soluble and water-soluble drugs. Particles have a mean diameter in the range of 10 to 250 nm. A wide variety of drugs and oxygen transporting perfluorocarbons may be encapsulated in the particles. In addition to drug delivery vehicles, the invention provides oxygen transporting blood substitutes, and nanoemulsions for extracorporeal maintenance of tissues prior to transplantation.

Priority: US1993-0063613 Applic. Date: 1993-05-18

Inventor: AMSELEM SHIMON (IL); FRIEDMAN DORON (IL)


Patent No.: US 5586981 A Issued: 1996-12- 24

Title: Treatment of cutaneous vascular and pigmented lesions

Applicant: HU XIN HUA (US)

Application No.: US1994-0295987 Applic. Date: 1994-08- 25

Abstract: According to the invention, a method is provided for disrupting the targeted lesion in skin, such as is necessary in treatment of vascular or pigmented lesions. A microplasma is generated in a target region of skin, the microplasma disrupting the skin ("plasma ablation") to enable removal of the targeted lesion. The microplasma absorbs radiation energy and expands, creating high pressure in the surrounding region which causes disruption of the targeted lesion in that region. A beam of pulsed laser radiation can be used to generate the microplasma by properly controlling the peak irradiance, the pulse duration and the focal spot size of the beam. The invention enables use of a laser having small pulse energy. A synchronized laser beam scan device can be used to scan the beam to provide a highly efficient system for rapid skin treatment.

Priority: US1994-0295987 Applic. Date: 1994-08-25

Inventor: HU XIN-HUA (US)


Patent No.: US 5587173 A Issued: 1996-12- 24

Title: Utilization of derivatives of 2,5 dihydroxyphenyl-carboxylic acid amides and their salts in preparation of a cosmetic or dermatological composition with a depigmenting action

Applicant: OREAL (FR)

Application No.: US1995-0465105 Applic. Date: 1995-06-05

Abstract: A cosmetic or dermatological composition with a depigmenting action comprises derivatives of 2,5-dihydroxyphenylcarboxylic acids, their homologs, and their salts, with the derivatives having the following structural formula: [IMAGE] (I) wherein: R1 represents OR5, OH, or [IMAGE] R5 is a linear or branched C1-C20 alkyl radical, a linear or branched C2 -C20 alkenyl radical, or a C1-C20 alkyl radical substituted by one or more hydroxy or alkoxy groups; r' and r'', identical or different, represent a hydrogen atom, a C1-C20 alkyl radical, a C2-C6 hydroxyalkyl radical, or a C3-C6 polyhydroxyalkyl, or r' and r'' taken together, with the nitrogen atom, form a heterocycle; the number of carbon atoms in the -(CH2)n-COR1 chain is less than or equal to 21; R2 and R3, identical or different, represent a hydrogen atom, a linear or branched C1-C4 alkyl radical, or a C1-C4 alkoxy; R4 represents a hydrogen atom or a linear or branched C1-C4 alkyl radical; and n is an integer from 0 to 20, provided that, when R2 and R3 represent a hydrogen atom, n is greater than or equal to 2.

Priority: US1995-0465105 Applic. Date: 1995-06-05; US1992-0913950 Applic. Date: 1992-07-17; FR1991-0009029 Applic. Date: 1991-07-17

Inventor: JUNINO ALEX (FR); LAGRANGE ALAIN (FR); N GUYEN QUANG L (FR); BOURBOULON MARIE-ALIX (FR)


Patent No.: US 5596986 A Issued: 1997-01- 28

Title: Blood oximeter

Applicant: SCICO INC (US)

Application No.: US1993-0018349 Applic. Date: 1993-02-16

Abstract: A backscatter type non- invasive blood oximeter utilizes a coherent, polarized and tuneable monochromatic light source to measure parameters related to blood oxygen content. A microprocessor calculates information related to blood oxygen content from the sensed information and a display system displays the blood oxygen content.

Priority: US1993-0018349 Applic. Date: 1993-02-16; US1991-0769153 Applic. Date: 1991-09-27; US1989-0324939 Applic. Date: 1989-03-17

Inventor: GOLDFARB DAVID (US)


Patent No.: US 5599342 A Issued: 1997 -02-04

Title: Method for treating pigmentation abnormalities using pulsed laser radiation with an elongated cross-section and apparatus for providing same

Applicant: CANDELA LASER CORP (US)

Application No.: US1995-0379776 Applic. Date: 1995-01- 27

Abstract: A method for treating pigmentation abnormalities in human skin involves the use of a beam of laser radiation having an elongated cross-sectional area. The beam of pulsed laser radiation having an elongated cross-section is produced using a pulsed laser and a delivery system. An elongated area on the skin including a pigmentation abnormality is irradiated with the laser beam. The laser pulse parameters are tailored to the specific type of pigmentation abnormality (e.g., vascular lesions or tattoos) being treated. The beam may have a cross-sectional area characterized by an aspect ratio of greater than two. Also, the beam may have an elliptical cross-sectional area.

Priority: US1995-0379776 Applic. Date: 1995-01-27

Inventor: HSIA JAMES C (US); SCHLIER ROBERT (US)


Patent No.: US 5605678 A Issued: 1997-02-25

Title: Photoprotective/cosmetic compositions comprising 2,4,6-tris[p-((2'-ethylhexyl)oxycarbonyl)anilino]-1,3,5-triazine andoily esters

Applicant: OREAL (FR)

Application No.: US1995-0463505 Applic. Date: 1995-06-05

Abstract: Topically applicable sunscreen/cosmetic compositions having improved cosmetic properties and well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a photoprotecting effective amount of 2,4,6-tris[p-((2'-ethylhexyl)oxycarbonyl)anilino]-1,3,5-triazine and (ii) at least one oil selected from among the esters of the structural formulae (I), (II) and (III): [IMAGE] (I) [IMAGE] (II) [IMAGE] (III) in a cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: FR1994-0006835 Applic. Date: 1994-06-03

Inventor: ASCIONE JEAN-MARC (FR); ALLARD DELPHINE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5605679 A Issued: 1997-02- 25

Title: Photoprotective/cosmetic compositions comprising at least one solid organic sunscreen compound and diphenylacrylate solvent therefor

Applicant: OREAL (FR)

Application No.: US1995-0463762 Applic. Date: 1995-06-05

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a photoprotecting effective amount of 4-methylbenzylidenecamphor and, optionally, of 4-(tert-butyl)-4'-methoxydibenzoylmethane and (ii) a 2-ethylhexyl alpha -cyano- beta , beta -diphenylacrylate sunscreen solvent, in an amount sufficient to substantially completely dissolve the total amount of the sunscreen constituent (i), in a cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: FR1994-0006833 Applic. Date: 1994-06- 03

Inventor: HANSENNE ISABELLE (FR); VAN LEEUWEN VICTORIA (FR)


Patent No.: US 5607664 A Issued: 1997-03- 04

Title: Photoprotective/cosmetic compositions comprising UV-A and/or UV-B sunscreens and polymers compatible therewith

Applicant: OREAL (FR)

Application No.: US1995 -0463221 Applic. Date: 1995-06-05

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a photoprotecting effective amount of at least one organic or inorganic UV screen, or mixture thereof, and (ii) at least one polymer compatible therewith, said at least one polymer comprising recurring structural units of the following formula (I) and recurring structural units of the following formulae (II) and/or (III): [IMAGE] (I) [IMAGE] (II) [IMAGE] (III) in a cosmetically acceptable vehicle, diluent or carrier therefor which comprises a continuous aqueous phase.

Priority: FR1994-0006836 Applic. Date: 1994- 06-03

Inventor: ASCIONE JEAN-MARC (FR); ALLARD DELPHINE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5609853 A Issued: 1997-03-11

Title: Photoprotective/cosmetic compositions comprising synergistic admixture of sunscreen compounds

Applicant: OREAL (FR)

Application No.: US1995-0464940 Applic. Date: 1995-06-05

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise a photoprotecting synergistically effective amount of (i) benzene-1,4-di(3-methylidene-10- camphorsulfonic)acid, optionally either partially or totally neutralized, and (ii) 2-ethylhexyl alpha - cyano- beta , beta -diphenylacrylate, in a cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: FR1994-0006829 Applic. Date: 1994-06-03

Inventor: HANSENNE ISABELLE (FR)


Patent No.: US 5612025 A Issued: 1997-03-18

Title: Cosmetic compositions containing a synergistic mixture of conditioning polymers

Applicant: OREAL (FR)

Application No.: US1995-0401887 Applic. Date: 1995-03-10

Abstract: The invention relates to new cosmetic compositions based on a synergistic mixture of conditioning polymers chosen from at least one quaternary polyammonium polymer (a) consisting of a sequence of units corresponding to the following formula (I): [IMAGE] in which p is an integer ranging from 1 to 6, D may not exist or can represent a - (CH2)r-CO- group in which r denotes a number equal to 4 or to 7, X- is an anion derived from an inorganic or organic acid, where the molecular mass of the polymer (a) is less than 100,000 and at least one polymer (b) consisting of 70% to 90% by weight of diallyldialkylammonium units in which the alkyl radical contains from 1 to 18 carbon atoms and of 30% to 10% by weight of acrylic or methacrylic units, and to their use for washing or for caring for the hair and/or the skin.

Priority: FR1994 -0002991 Applic. Date: 1994-03-15

Inventor: CAUWET-MARTIN DANIELE (FR); DUBIEF CLAUDE (FR)


Patent No.: US 5616331 A Issued: 1997-04-01

Title: Storage-stable, ultrafine oil-in-water emulsion nanopigmented sunscreen/cosmetic compositions

Applicant: OREAL (FR)

Application No.: US1995-0386092 Applic. Date: 1995-02-09

Abstract: Stable and homogeneous, topically applicable sunscreen/cosmetic compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-A and/or UV-B irradiation, particularly solar radiation, and which display excellent transparency on the skin, comprise a storage-stable, ultrafine oil-in-water emulsion of a photoprotecting effective amount of homogeneously and finely dispersed particulates of at least one inorganic nanopigment which comprises a metal oxide, for example titanium dioxide, wherein the average particle size of the globules comprising the oily phase of the emulsion characteristically range from 100 nm to 1,000 nm.

Priority: FR1994-0001455 Applic. Date: 1994-02- 09

Inventor: ALLARD DELPHINE (FR); ASCIONE JEAN-MARC (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5618520 A Issued: 1997 -04-08

Title: Photostable filtering cosmetic composition containing a UV-A filter and a filtering polymer of the benzotriazole silcone type

Applicant: OREAL (FR)

Application No.: US1995-0382310 Applic. Date: 1995-05-04

Abstract: A photostable, filtering cosmetic composition for protecting human epidermis and hair against UV rays comprises, in a cosmetically acceptable carrier having at least one fatty phase 0.5 to 4% by weight of 4-(tert.-butyl) 4'-methoxy dibenzoylmethane and 0.1 to 20% by weight of a filtering polymer of the benzotriazole silicone type containing at least one unit of formula (1), where R' is a C1-C30 hydrocarbon group, a C1-C8 halogenated hydrocarbon group or a trimethylsilyloxy group; a is 1 or 2; X=- A-Y where A is an aliphatic or aromatic bivalent hydrocarbon radical having at least 2 carbon atoms and optionally containing one or more oxygen atoms; Y is a 2-(2'-hydroxyphenyl)benzotriazole residue optionally containing one or more C1-C8 alkyl, C2-C8 alkenyl, halogen, alkoxy, carboxy, hydroxy or amino substituents, the weight ratio of the benzotriazole silicone to the 4-(tert.-butyl) 4'-methoxy dibenzoylmethane being between 1 and 10.

Priority: FR1992-0011099 Applic. Date: 1992-09- 17; WO1993-FR00886 Applic. Date: 1993-09-15

PCT Info:
PCT No. PCT/FR93/00886
Sec 371 Date May 4, 1995
Sec. 102(e) Date May 4, 1995
PCT Filed Sep. 15, 1993
PCT Pub. No. WO94/06404
PCT Pub. Date Mar. 31, 1994

Inventor: HANSENNE ISABELLE (FR); FORESTIER SERGE (FR); DEFLANDRE ANDRE (FR)


Patent No.: US 5618521 A Issued: 1997-04-08

Title: Photoprotective/cosmetic compositions comprising antioxidants and filamentous bacterial extracts

Applicant: OREAL (FR)

Application No.: US1995-0491454 Applic. Date: 1995-06- 16

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, whether before, during and/or after exposure to such UV irradiation, particularly solar radiation, comprise a photoprotecting effective amount of (i) at least one antioxidant, for example tocopherol or derivative thereof, and (ii) at least one extract of at least one nonphotosynthetic and nonfructifying filamentous bacteria, for example of the order Beggiatoales, in a cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: FR1994-0007397 Applic. Date: 1994-06- 16

Inventor: DE RIGAL JEAN (FR); LEVEQUE JEAN-LUC (FR); CONTAMIN JEAN-CLAUDE (FR); AUBERT LUCIEN (FR)


Patent No.: US 5635163 A Issued: 1997-06-03

Title: Screening cosmetic compositions containing a hydrophilic agent comprising at least one sulphonic acid radical

Applicant: OREAL (FR)

Application No.: US1995-0387781 Applic. Date: 1995-04-07

Abstract: The invention relates to screening cosmetic compositions containing at least one hydrophilic agent which screens ultraviolet radiation and contains at least one sulphonic acid radical -SO3H and at least one amino-functional silicone derivative. Application to the protection of skin and hair against the effects of ultraviolet radiation.

Priority: FR1993-0007447 Applic. Date: 1993-06-21; WO1994- FR00751 Applic. Date: 1994-06-21

PCT Info:
PCT No. PCT/FR94/00751
Sec 371 Date Apr. 7, 1995
Sec. 102(e) Date Apr. 7, 1995
PCT Filed Jun. 21, 1994
PCT Pub. No. WO95/00111
PCT Pub. Date Jan. 5, 1995

Inventor: HANSENNE ISABELLE (FR)


Patent No.: US 5643557 A Issued: 1997-07- 01

Title: Screening cosmetic composition containing a mixture of 1,4-benzenedi(3- methylidene-10-camphosulfonic) acid, partially or completely neutralized, and metal oxide nanopigments

Applicant: OREAL (FR)

Application No.: US1993-0119651 Applic. Date: 1993-09-13

Abstract: The invention relates to a screening cosmetic composition comprising, in a mixture, 0.5 to 10% by weight of metal oxide nanopigments chosen from titanium, zinc, cerium or zirconium oxide or mixtures thereof, with a mean diameter of less than 100 nm, and 0.1 to 10% by weight of 1,4-benzenedi(3-methylidene-10-camphosulfonic) acid or one of its alkali metal, ammonium, amine, alkanolamine, Ca, Zn, Mg, Ba, Al or Zr salts, in a cosmetically acceptable carrier. This composition is useful as composition for protecting the human epidermis or the hair against UV rays or as make-up.

Priority: US1993-0119651 Applic. Date: 1993-09-13; FR1991 -0007255 Applic. Date: 1991-06-13; US1992-0897498 Applic. Date: 1992-06-12

Inventor: ETEVE MARTINE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5643581 A Issued: 1997-07- 01

Title: Cosmetic compositions and their uses

Applicant: OREAL (FR)

Application No.: US1994-0280875 Applic. Date: 1994-07-27

Abstract: New cosmetic compositions characterized in that they comprise, in a cosmetically acceptable carrier, at least one pseudolatex based on a multiblock polycondensate which contains a polysiloxane block and a polyurethane and/or polyurea block, wherein the polyurethane and/or polyurea block further comprises anionic or cationic groups. These compositions can be employed especially in the cosmetic field of hair care, of make-up or of skin care.

Priority: FR1993-0009286 Applic. Date: 1993-07- 28

Inventor: MOUGIN NATHALIE (FR); MONDET JEAN (FR)


Patent No.: US 5647866 A Issued: 1997-07- 15

Title: Method of hair depilation

Application No.: US1996-0645868 Applic. Date: 1996-05-14

Abstract: The present invention relates to a method of hair depilation comprising the steps of providing an augmentation compound that readily absorbs a selected wavelength of laser light energy, encapsulating the augmentation compound within a liposimal carrier, applying an effective amount of the encapsulated augmentation compound to a region of tissue to be depilated sufficient to cause the compound to accumulate within the dermis surrounding each hair follicle and respective papilla, providing a laser light applicator capable of producing a wavelength of energy matched to the selected wavelength of absorption for the augmentation compound, positioning the laser light applicator above the region of skin treated with the augmentation compound and, applying a pulse of laser energy of the selected wavelength to the region of skin treated with the augmentation compound,; the pulse of laser energy having a radiant exposure dose of sufficient energy and duration to cause damage to the hair follicle and papilla so that hair regrowth is prevented and surrounding tissue remains undamaged.

Priority: US1996-0645868 Applic. Date: 1996-05-14; US1995-0417857 Applic. Date: 1995-04-07; US1993-0149502 Applic. Date: 1993-11-09

Inventor: ZAIAS NARDO (US); MEHL SR THOMAS L (US)


Patent No.: US 5651731 A Issued: 1997-07-29

Title: Method and apparatus for debeaking poultry

Applicant: NOVA TECH ENGINEERING INC (US)

Application No.: US1995-0493928 Applic. Date: 1995-06-23

Abstract: The present invention relates to debeaking turkey and chick poultry through non-contact thermal transfer from a source of high frequency heat generating radiation. The present invention directs heat onto the upper beak of a live bird by convection or radiation to thereby affect the continued growth of the beak. Such heating of the bird's upper beak provides a debeaking method which allows the bird's upper beak to stay in place for several days allowing the bird to eat and drink. Heating the portion of the upper beak also allows the poultry tongue and lower beak to be shielded from the heat causing less trauma and injury to the bird. The heat may be directed onto the poultry upper beak by radiation or convection.

Priority: US1995- 0493928 Applic. Date: 1995-06-23

Inventor: GORANS MARC S (US); JOHNSON SCOTT C (US)


Patent No.: US 5653706 A Issued: 1997-08-05

Title: Dermatological laser treatment system with electronic visualization of the area being treated

Applicant: LUCID TECH INC (US)

Application No.: US1995-0395223 Applic. Date: 1995-02-27

Abstract: A hand held microsurgical instrument for applying laser energy to selected locations (sites) in an area under the skin (or other exposed translucent tissue) to provide localized photothermolysis of underlying tissue at these sites, is described. The laser energy is focused into a spot within the tissue. This spot is of sufficiently small size so that the energy density is sufficient to provide surgical or treatment effects within the tissue without damaging the surface tissue. In dermatology, for example, the technique can be used to destroy endothelial cells in blood vessels which are desired to be removed, such spider veins (nevi) in the skin, hair follicles to prevent hair growth therefrom, or other microsurgical procedures. The area is visualized while the laser beam is steered, using a deflection system, in X and Y coordinates.; A telecentric optical system, in which a mirror of the deflection system is located, directs the laser light essentially perpendicular to the area to be treated as the beam is scanned over the area. The optical system also focuses illumination light reflected from the area to a sensor matrix of a CCD video camera. The reflected illumination light is imaged essentially parallel to the optical axis in the object space thereby providing a precise, high resolution image corresponding to the area. The laser beam may be tracked as it is deflected over the area to the selected locations by visualization thereof on a display or monitor associated with the video camera. The locations are then apparent to the treating physician who can then effect an increase of the beam power or turn the beam on so as to treat the tissue in the selected locations.

Priority: US1995-0395223 Applic. Date: 1995-02-27; US1993-0094296 Applic. Date: 1993-07- 21

Inventor: ZAVISLAN JAMES M (US); EASTMAN JAY M (US)


Patent No.: US 5658555 A Issued: 1997-08- 19

Title: Photoprotective/cosmetic compositions comprising synergistic admixture of sunscreen compounds/nanopigments

Applicant: OREAL (FR)

Application No.: US1995-0463304 Applic. Date: 1995-06-05

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise a photoprotecting synergistically effective amount of (i) 2,4,6-tris[p-((2'-ethylhexyl)oxycarbonyl) anilino]-1,3,5-triazine and benzene-1,4-di(3-methylidene-10-camphorsulfonic)acid, optionally either partially or totally neutralized, together with photoprotecting synergistically effective amounts of (ii) particulates of at least one inorganic nanopigment which comprises a metal oxide, in a cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: FR1994-0006832 Applic. Date: 1994-06-03

Inventor: ASCIONE JEAN-MARC (FR); ALLARD DELPHINE (FR)


Patent No.: US 5658575 A Issued: 1997-08- 19

Title: Cosmetic or dermatological composition comprising an oil-in-water emulsion based on oily globules provided with a lamellar liquid crystal coating

Applicant: OREAL (FR)

Application No.: US1994-0301571 Applic. Date: 1994-09-07

Abstract: Cosmetic or dermatological compositions comprising an oil-in-water type emulsion containing oily globules which are coated with a lamellar liquid crystal coating and are dispersed in an aqueous phase, in which each oily globule contains at least one lipophilic compound which is cosmetically or dermatologically active and is individually coated with a monolamellar or oligolamellar layer of at least one lipophilic surface-active agent, at least one hydrophilic surface-active agent, and at least one fatty acid, the coated oily globules having a mean diameter of less than 500 nanometers, preferably less than 200 nanometers, and the oily phase contains a basic agent in the dissolved state, exhibit good skin and hair penetration.

Priority: FR1993-0010588 Applic. Date: 1993-09- 07

Inventor: RIBIER ALAIN (FR); SIMONNET JEAN-THIERRY (FR); GRIAT JACQUELINE (FR)


Patent No.: US 5662932 A Issued: 1997 -09-02

Title: Solid fat nanoemulsions

Applicant: PHARMOS CORP (US)

Application No.: US1996-0697704 Applic. Date: 1996-08-27

Abstract: The present invention provides pharmaceutical compositions comprising nanoemulsions of particles comprising a lipid core which is in a solid or liquid crystalline phase at 25 DEG C., stabilized by at least one phospholipid envelope, for the parenteral, oral, intranasal, rectal, or topical delivery of both fat-soluble and water-soluble drugs. Particles have a mean diameter in the range of 10 to 250 nm. A wide variety of drugs and oxygen transporting perfluorocarbons may be encapsulated in the particles. In addition to drug delivery vehicles, the invention provides oxygen transporting blood substitutes, and nanoemulsions for extracorporeal maintenance of tissues prior to transplantation.

Priority: US1996-0697704 Applic. Date: 1996-08-27; US1993-0063613 Applic. Date: 1993-05-18

Inventor: AMSELEM SHIMON (IL); FRIEDMAN DORON (IL)


Patent No.: US 5665368 A Issued: 1997 -09-09

Title: Sprayable compositions containing dispersed powders and methods for using the same

Applicant: ESTEE LAUDER INC (US)

Application No.: US1996-0753031 Applic. Date: 1996-11-19

Abstract: Stable, sprayable compositions suitable for topical application to human skin or hair are provided, along with a method for their preparation. The compositions comprise water-in-oil emulsions and a variety of substantially insoluble dispersed powder. The compositions are useful for applying color to human skin or hair, for protecting human skin from ultraviolet radiation, and for treating human skin or hair with a dermatologically active agent. The compositions have unique suspending power, stability and dispersibility for water-in-oil emulsions.

Priority: US1996-0753031 Applic. Date: 1996-11-19; US1994-0333707 Applic. Date: 1994-11-03

Inventor: LENTINI PETER J (US); TCHINNIS PAUL C (US)


Patent No.: US 5667765 A Issued: 1997-09- 16

Title: Photoprotective/cosmetic compositions comprising at least one solid organic sunscreen compound and salicylate solvents therefor

Applicant: OREAL (FR)

Application No.: US1995-0461015 Applic. Date: 1995-06-05

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a photoprotecting effective amount of at least one of the sunscreen compounds 4 -methylbenzylidenecamphor and/or 4-(tert-butyl)-4'-methoxydibenzoylmethane and (ii) at least one homomenthyl and/or octyl salicylate sunscreen solvent, in an amount sufficient to substantially completely dissolve the total amount of the at least one sunscreen compound (i), in a cosmetically acceptable vehicle, diluent or carrier therefore.

Priority: FR1994-0006830 Applic. Date: 1994-06-03

Inventor: HANSENNE ISABELLE (FR); VAN LEEUWEN VICTORIA (FR)


Patent No.: US 5667792 A Issued: 1997-09- 16

Title: Derivatives of 2,5-dihydroxyphenylcarboxylic acids, and their utilization in cosmetic or dermatological compositions with a depigmenting action

Applicant: OREAL (FR)

Application No.: US1996-0684705 Applic. Date: 1996-07-19

Abstract: A cosmetic or dermatological composition with a depigmenting action comprises derivatives of 2,5- dihydroxyphenylcarboxylic acids, their homologs, and their salts, with the derivatives having the following structural formula: [IMAGE] (I) wherein: R1 represents OR5, OH, or [IMAGE] R5 is a linear or branched C1-C20 alkyl radical, a linear or branched C2-C20 alkenyl radical, or a C1-C20 alkyl radical substituted by one or more hydroxy or alkoxy groups; r' and r'', identical or different, represent a hydrogen atom, a C1-C20 alkyl radical, a C2-C6 hydroxyalkyl radical, or a C3-C6 polyhydroxyalkyl, or r' and r'' taken together, with the nitrogen atom, form a heterocycle; the number of carbon atoms in the - (CH2)n-COR1 chain is less than or equal to 21; R2 and R3, identical or different, represent a hydrogen atom, a linear or branched C1-C4 alkyl radical, or a C1-C4 alkoxy; R4 represents a hydrogen atom or a linear or branched C-C4 alkyl radical; and n is an integer from 0 to 20, provided that, when R2 and R3 represent a hydrogen atom, n is greater than or equal to 2.

Priority: US1996-0684705 Applic. Date: 1996-07-19; FR1991-0009029 Applic. Date: 1991-07-17; US1995-0465105 Applic. Date: 1995- 06-05; US1992-0913950 Applic. Date: 1992-07-17

Inventor: JUNINO ALEX (FR); LAGRANGE ALAIN (FR); N GUYEN QUANG LAN (FR); BOURBOULON MARIE-ALIX (FR)


Patent No.: US 5667800 A Issued: 1997-09- 16

Title: Topical preparation containing a suspension of solid lipid particles

Applicant: YAMANOUCHI EUROP BV (NL)

Application No.: US1995- 0467212 Applic. Date: 1995-06-06

Abstract: An aqueous suspension of solid lipoid nanoparticles, comprising at least one lipid and preferably also at least one emulsifier, for topical application to the body, is provided. The solid lipoid nanoparticles have a mean particle size of between 50-1000 nm and their concentration is between 0.01-60 wt %, by weight of the suspension. Also topical preparations, comprising said suspension of solid lipoid nanoparticles, are provided. A medicament can be incorporated into the continuous phase of the suspension or in a vehicle, which is added to said suspension. The invention further provides manufacturing methods for the aqueous suspension of solid lipoid nanoparticles as well as for preparations comprising such suspension.

Priority: US1995-0467212 Applic. Date: 1995-06-06; EP1991-0200664 Applic. Date: 1991-03-25; US1993-0131480 Applic. Date: 1993-10-04; US1992-0857467 Applic. Date: 1992-03- 25

Inventor: DE VRINGER TOM (NL)


Patent No.: US 5670139 A Issued: 1997-09- 23

Title: Stable nanopigmented sunscreen/cosmetic compositions

Applicant: OREAL (FR)

Application No.: US1995-0391355 Applic. Date: 1995-02- 21

Abstract: Stable and homogeneous, topically applicable sunscreen/cosmetic compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-A and/or UV-B irradiation, particularly solar radiation, and which display excellent transparency on the skin, comprise a storage-stable, ultrafine oil-in-water emulsion resistant to phase separation/settling, of a photoprotecting effective amount of homogeneously and finely dispersed particulates of at least one inorganic nanopigment which comprises a metal oxide, for example titanium dioxide, as well as a stabilizing amount of at least one mixed silicate which comprises alkali and/or alkaline earth metals, and further wherein the average particle size of the globules comprising the oily phase of the emulsion characteristically ranges from 100 nm to 1,000 nm.

Priority: FR1994-0001861 Applic. Date: 1994-02-18

Inventor: ALLARD DELPHINE (FR); ASCIONE JEAN-MARC (FR)


Patent No.: US 5670742 A Issued: 1997-09- 23

Title: EMI protected aircraft

Applicant: THRESHOLD TECHNOLOGIES INC (US)

Application No.: US1994-0191096 Applic. Date: 1994-02-04

Abstract: A device for shielding aircraft avionics and other electronic equipment from electromagnetic radiation generated by electronic devices used aboard the aircraft. The device includes a contiguous conductive shield which can be of wire mesh and which partially or completely surrounds a compartment or compartments of the aircraft, such as the passenger compartment and cargo compartments, and absorbs and dissipates the electromagnetic radiation which originates in the compartment from the electronic devices. The aircraft windows are also shielded with the conductive shield or, alternatively, may be coated with a transparent thin conductive polymer to allow better viewing.

Priority: US1994-0191096 Applic. Date: 1994-02-04

Inventor: JONES SCOTT A (US)


Patent No.: US 5679656 A Issued: 1997-10- 21

Title: Artificial tanning compositions comprising dihydroxyacetone/alkylpolysaccharides/fatty alcohols

Applicant: OREAL (FR)

Application No.: US1995-0567280 Applic. Date: 1995-12-05

Abstract: Improvedly stable and effective, topically applicable cosmetic compositions well suited for artificially tanning and/or darkening human skin, comprise, in a cosmetically acceptable vehicle, diluent or carrier therefor, an effective artificial tanning amount of dihydroxyacetone, in immixture with at least one alkylpolysaccharide and at least one fatty alcohol, and, optionally, at least one polysaccharide.

Priority: FR1994-0014593 Applic. Date: 1994-12-05

Inventor: HANSENNE ISABELLE (FR)


Patent No.: US 5679829 A Issued: 1997-10-21

Title: Arginine derivatives, process of preparation, uses, and compositions comprising them

Applicant: OREAL (FR)

Application No.: US1996-0590445 Applic. Date: 1996-01-23

Abstract: New arginine derivatives containing an N alpha -alkyloxycarbonyl group of formula (I) [IMAGE] in which R represents a linear or branched alkyl radical having from 8 to 22 carbon atoms, salts thereof, and mixtures of the derivatives and the salts. A process for the preparation of these derivatives, salts, and mixtures and use of such derivatives, salts, and mixtures, especially in cosmetics. Compositions, especially cosmetic compositions, comprising the derivatives, salts, and mixtures.;New arginine derivatives containing an N alpha -alkyloxycarbonyl group of formula (I) [IMAGE] in which R represents a linear or branched alkyl radical having from 8 to 22 carbon atoms, salts thereof, and mixtures of the derivatives and the salts. A process for the preparation of these derivatives, salts, and mixtures and use of such derivatives, salts, and mixtures, especially in cosmetics. Compositions, especially cosmetic compositions, comprising the derivatives, salts, and mixtures.

Priority: FR1995-0001114 Applic. Date: 1995-01-31

Inventor: BORDIER THIERRY (FR); PHILIPPE MICHEL (FR); GENARD SYLVIE (FR)


Patent No.: US 5686085 A Issued: 1997-11-11

Title: Lysine derivatives, process of preparation, uses, and compositions comprising them

Applicant: OREAL (FR)

Application No.: US1996- 0590444 Applic. Date: 1996-01-23

Abstract: New lysine derivatives containing a containing an alkylsulphonyl or alkylaminocarbonyl group of formula (I): COOH-CH(NH2)-(CH2)4-NH-Xin which X represents an -SO2R or -CONHR group, where R represents a linear or branched, saturated or unsaturated, alkyl radical having from 8 to 22 carbon atoms, salts thereof, and mixtures of the derivatives and the salts. A process for the preparation of these derivatives, salts, and mixtures and use of such derivatives, salts, and mixtures, especially in cosmetics. Compositions, especially cosmetic compositions, comprising the derivatives, salts, and mixtures.

Priority: FR1995-0001113 Applic. Date: 1995-01-31

Inventor: BORDIER THIERRY (FR); PHILIPPE MICHEL (FR)


Patent No.: US 5688527 A Issued: 1997 -11-18

Title: Lysine derivatives, process of preparation, uses, and compositions comprising them

Applicant: OREAL (FR)

Application No.: US1996-0590446 Applic. Date: 1996-01-23

Abstract: New lysine derivatives containing a fluoroalkyloxycarbonyl or fluoroalkylsulphonyl group of formula:COOH-CH(NH2)-(CH2)4-NH-X-(CH2)n-Rin which n ranges from 0 and 4, X represents a divalent COO or SO2 group and R represents a linear or branched perfluoroalkyl radical having from 4 to 20 carbon atoms, salts thereof, and mixtures of the derivatives and the salts. A process for the preparation of these derivatives, salts, and mixtures and use of such derivatives, salts, and mixtures, especially in cosmetics. Compositions, especially cosmetic compositions, comprising the derivatives, salts, and mixtures.

Priority: FR1995-0001112 Applic. Date: 1995-01-31

Inventor: BORDIER THIERRY (FR); PHILIPPE MICHEL (FR)


Patent No.: US 5690915 A Issued: 1997 -11-25

Title: Screening cosmetic composition containing a mixture of 1,4-benzenedi(3- methylidene-10-camphosulfonic) acid, partially or completely neutralized, and metal oxide nanopigments

Applicant: OREAL (FR)

Application No.: US1995-0458187 Applic. Date: 1995-06-02

Abstract: The invention relates to a screening cosmetic composition comprising, in a mixture, 0.5 to 10% by weight of metal oxide nanopigments chosen from titanium, zinc, cerium or zirconium oxide or mixtures thereof, with a mean diameter of less than 100 nm, and 0.1 to 10% by weight of 1,4-benzenedi(3-methylidene-10-camphosulfonic) acid or one of its alkali metal, ammonium, amine, alkanolamine, Ca, Zn, Mg, Ba, Al or Zr salts, in a cosmetically acceptable carrier. This composition is useful as composition for protecting the human epidermis or the hair against UV rays or as make-up.

Priority: US1995-0458187 Applic. Date: 1995-06-02; FR1991 -0007255 Applic. Date: 1991-06-13; US1993-0119651 Applic. Date: 1993-09-13; US1992-0897498 Applic. Date: 1992-06-12

Inventor: ETEVE MARTINE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5690917 A Issued: 1997-11- 25

Title: Screening cosmetic composition containing a mixture of 1,4-benzenedi (3- methylidene-10-camphosulfonic) acid, partially or completely neutralized, and metal oxide nanopigments

Applicant: OREAL (FR)

Application No.: US1995-0458191 Applic. Date: 1995-06-02

Abstract: The invention relates to a screening cosmetic composition comprising, in a mixture, 0.5 to 10% by weight of metal oxide nanopigments chosen from titanium, zinc, cerium or zirconium oxide or mixtures thereof, with a mean diameter of less than 100 nm, and 0.1 to 10% by weight of 1,4-benzenedi(3-methylidene-10-camphosulfonic) acid or one of its alkali metal, ammonium, amine, alkanolamine, Ca, Zn, Mg, Ba, Al or Zr salts, in a cosmetically acceptable carrier. This composition is useful as composition for protecting the human epidermis or the hair against UV rays or as make-up.

Priority: US1995-0458191 Applic. Date: 1995-06-02; FR1991 -0007255 Applic. Date: 1991-06-13; US1993-0119651 Applic. Date: 1993-09-13; US1992-0897498 Applic. Date: 1992-06-12

Inventor: ETEVE MARTINE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5693329 A Issued: 1997-12- 02

Title: Cosmetic composition which prevents or attenuates the photo-reactivity of titanium dioxide nanopigments

Applicant: OREAL (FR)

Application No.: US1995 -0527429 Applic. Date: 1995-09-13

Abstract: Cosmetic composition, characterized in that it contains titanium dioxide nanopigments coated with at least aluminium derivatives in a cosmetically acceptable, fairly nonpolar medium having a conductivity of less than 100 mu Siemens and containing at least one fatty phase.

Priority: FR1994-0010924 Applic. Date: 1994-09- 13

Inventor: MARCHI-LEMANN PATRICIA (FR); COLIN CHRISTIAN (FR)


Patent No.: US 5695747 A Issued: 1997-12- 09

Title: Cosmetic composition containing a mixture of metal oxide nanopigments and melanine pigments

Applicant: OREAL (FR)

Application No.: US1995-0451982 Applic. Date: 1995-05-26

Abstract: The invention relates to a cosmetic composition comprising, in a mixture, 0.10 to 15% by weight of metal oxide nanopigments chosen from titanium, zinc, cerium or zirconium oxide or mixtures thereof, with a mean diameter of less than 100 nm, and 0.001 to 2% by weight of melanin pigments derived from natural or synthetic sources with a mean diameter of between 10 and 20,000 nm, in a cosmetically acceptable carrier. This composition is useful as a composition for protecting the human epidermis or the hair against UV rays or as make-up.

Priority: US1995-0451982 Applic. Date: 1995-05-26; FR1991-0007324 Applic. Date: 1991-06-14; US1993-0155787 Applic. Date: 1993-11-23; US1992-0897497 Applic. Date: 1992-06-12

Inventor: FORESTIER SERGE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5701902 A Issued: 1997-12-30

Title: Spectroscopic burn injury evaluation apparatus and method

Applicant: CEDARS SINAI MEDICAL CENTER (US)

Application No.: US1994-0306118 Applic. Date: 1994-09-14

Abstract: A burn evaluation apparatus and related method, that allows a surgeon to make a quick evaluation of the extent and depth of a skin burn injury by employing induced ultraviolet or blue light fluorescence spectroscopy and visible and infrared reflectance spectroscopy. The apparatus monitors the condition of the structural and metabolic constituents in the injured skin. The apparatus includes a plurality of light sources, a sensor, a microprocessor, and several optical fiber bundles. The light sources emit excitation light at predetermined wavelengths, and when each is activated, the sensor measures the amount return light received within several wavelength bands of interest. A side fiber bundle spaced about a centimeter from a main fiber bundle assists in detecting tissue water below the burn area.; By optically evaluating the skin at the burn site, the apparatus prevents the unnecessary removal of viable skin that will heal spontaneously within a few weeks, thereby reducing the amount of skin that must be surgically grafted.

Priority: US1994-0306118 Applic. Date: 1994-09- 14

Inventor: VARI SANDOR G (US); MAAREK JEAN-MICHEL I (US)


Patent No.: US 5707613 A Issued: 1998-01- 13

Title: Spontaneously formed clear silicone microemulsions

Applicant: DOW CORNING (US)

Application No.: US1996-0694722 Applic. Date: 1996-08- 09

Abstract: A method of spontaneously forming a highly stable clear microemulsion by combining (i) water; (ii) a volatile cyclic methyl siloxane or volatile linear methyl siloxane; and (iii) a silicone polyether surfactant. The amounts of each component are such that the composition is in the form of a microemulsion. The volatile methyl siloxane is present in the microemulsion in the form of particles having an average diameter of less than about 100 nanometers. The microemulsion is useful in personal care products.

Priority: US1996-0694722 Applic. Date: 1996-08-09; US1995-0560561 Applic. Date: 1995-11-20

Inventor: HILL RANDAL MYRON (US)


Patent No.: US 5713845 A Issued: 1998-02- 03

Title: Laser assisted drug delivery

Applicant: THERMOLASE CORP (US)

Application No.: US1995-0489352 Applic. Date: 1995-06-12

Abstract: The present invention provides a process for laser assisted drug delivery through the skin. A drug and a explosive absorber of light energy are applied topically to the skin. The treated area of the skin is illuminated with very short pulses of light which is preferentially absorbed by the absorber causing a very large number of tiny explosions. The tiny explosion forces portions of the drug to penetrate into the skin. A preferred embodiment utilizes small graphite particles and an Nd:YAG short pulse laser.

Priority: US1995-0489352 Applic. Date: 1995-06-12; US1994-0280928 Applic. Date: 1994-07-26; US1994-0257021 Applic. Date: 1994-06-08; US1993-0005810 Applic. Date: 1993-01-19; US1991 -0783789 Applic. Date: 1991-10-29

Inventor: TANKOVICH NIKOLAI (US)


Patent No.: US 5723499 A Issued: 1998-03- 03

Title: Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof

Applicant: CIRD GALDERMA (FR)

Application No.: US1994-0356913 Applic. Date: 1994-12-15

Abstract: Novel pharmaceutically/cosmetically-active polycyclic aromatic compounds have the structural formula (I): [IMAGE] (I) wherein Ar is a radical having one of the formulae (a)-(i): [IMAGE] (a) GE] (e) [IMAGE] (f) [IMAGE] (g) [IMAGE] (h) [IMAGE] (i) and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

Priority: FR1993- 0015068 Applic. Date: 1993-12-15

Inventor: CHARPENTIER BRUNO (FR); BERNARDON JEAN-MICHEL (FR)


Patent No.: US 5730962 A Issued: 1998-03-24

Title: Depigmenting cosmetic or dermatologic composition containing a benzofuran derivative and its use in depigmentating skin

Applicant: OREAL (FR)

Application No.: US1992-0914150 Applic. Date: 1992-07- 16

Abstract: A depigmenting cosmetic or dermatologic composition for use in bleaching the skin or treating pigmental spots contains in a vehicle suitable for topical application to the skin a benzofuran derivative having the formula [IMAGE] (I) wherein the OH function occupies position 5 or 6, R1 and R2, each independently, represent hydrogen or alkyl having 1-4 carbon atoms, n is 0 or 1, when n is 0, the C2-C3 bond is a double bond, and when n is 1, the C2-C3 bond is a single bond.

Priority: FR1991-0009028 Applic. Date: 1991-07-17

Inventor: JUNINO ALEX (FR); N GUYEN QUANG LAN (FR); TULOUP REMY (FR); BLAISE CHRISTIAN (FR)


Patent No.: US 5730993 A Issued: 1998-03- 24

Title: Nanopigmented sunscreen/cosmetic compositions

Applicant: SOCIETE L'OREAL SA (FR)

Application No.: US1996-0760317 Applic. Date: 1996-12- 04

Abstract: Stable and homogeneous, topically applicable sunscreen/cosmetic compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-A and/or UV-B irradiation, particularly solar radiation, and which display excellent transparency on the skin, comprise a storage-stable, ultrafine oil-in-water emulsion of a photoprotecting effective amount of homogeneously and finely dispersed particulates of at least one inorganic nanopigment which comprises a metal oxide, for example titanium dioxide, wherein the average particle size of the globules comprising the oily phase of the emulsion characteristically range from 100 nm to 1,000 nm.

Priority: US1996-0760317 Applic. Date: 1996-12-04; FR1994-0001455 Applic. Date: 1994 -02-09; US1995-0386092 Applic. Date: 1995-02-09

Inventor: ALLARD DELPHINE (FR); ASCIONE JEAN-MARC (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5733854 A Issued: 1998-03- 31

Title: Cleaning compositions including derivatized guar gum composition including nonionic and cationic groups which demonstrate excellent solution clarity properties

Applicant: RHONE POULENC INC (US)

Application No.: US1996-0736866 Applic. Date: 1996-10-25

Abstract: A detergent composition useful for cleaning and/or conditioning human hair or skin or cleaning dishes or clothing which contains NaCl or NH4Cl and further contains a nonionically and cationically derivatized polygalactomannan, the molecular substitution of the nonionic substituent being between about 0.4 and about 1.2 and the degree of substitution of the cationic substituent being between about 0.20 to about 1.0, said detergent composition having a viscosity of greater than about 500 centipoises and said composition having greater than 75% light transmission at a wavelength of from about 500-600 nanometers is provided. Also disclosed is the use of an amphoteric and nonionic substituted derivatized polygalactomannan for such uses.

Priority: US1996-0736866 Applic. Date: 1996-10-25

Inventor: CHOWDHARY MANJIT SINGH (US); ROBINSON FRED (US)


Patent No.: US 5733895 A Issued: 1998-03-31

Title: Screening cosmetic composition comprising one nanopigment of metallic oxide and fat-soluble screening polymer

Applicant: OREAL (FR)

Application No.: US1993-0039324 Applic. Date: 1993-04- 23

Abstract: This invention relates to a filtering cosmetic composition characterized in that it is comprised, in a cosmetically acceptable carrier, at least one nanopigment of metal oxides selected amongst titanium, zinc, cerium, zirconium, iron oxides or mixtures thereof, having an average diameter lower than 100 nm, and at least one polymer carrying at least one ultraviolet absorbing group selected amongst liposoluble polymers having a hydrocarbonated structure and the polymers of siloxanic structure and such compositions are useful for the protection of human epidermis and hair against UV radiation or as make-up composition.

Priority: FR1991-0010731 Applic. Date: 1991-08-29; WO1992-FR00821 Applic. Date: 1992-08-25

PCT Info:
PCT No. PCT/FR92/00821
Sec 371 Date Apr. 23, 1993
Sec. 102(e) Date Apr. 23, 1993
PCT Filed Aug. 25, 1992
PCT Pub. No. WO93/04666
PCT Pub. Date Mar. 18, 1993

Inventor: FORESTIER SERGE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5747009 A Issued: 1998-05-05

Title: Dihydroxyacetone-based emulsion and its use in cosmetics

Applicant: OREAL (FR)

Application No.: US1996-0530168 Applic. Date: 1996-03-14

Abstract: Stable skin coloring cosmetic emulsion comprising A) from 50 to 92% by weight, based on the total emulsion weight, of an aqueous phase containing from 0.5 to 10% by weight, based on the total emulsion weight, of dihydroxyacetone and B) from 8 to 50% by weight, based on the total emulsion weight, of a fatty phase comprising from 5 to 15% by weight of isoparaffin or poly- alpha -olefin, from 3 to 7% by weight of an emulsifying agent consisting of a mixture of saturated or unsaturated sorbitol and glycerol esters of C18 fatty acids with a straight or branched chain, optionally including hydroxyl, said esters being oxyethylenated and oxypropylenated, the total number of ethylene oxide and propylene oxide being less than or equal to 5,; and from 0 to 15% by weight of the additional fatty bodies, all of the percentages being based on the total emulsion weight. The water-in- oil emulsion can be used to obtain a triple water-in-oil-in-water emulsion.

Priority: FR1993-0003600 Applic. Date: 1993-03-29; WO1994-FR00341 Applic. Date: 1994-03-28

PCT Info:
PCT No. PCT/FR94/00341
Sec 371 Date Mar. 14, 1996
Sec. 102(e) Date Mar. 14, 1996
PCT Filed Mar. 28, 1994
PCT Pub. No. WO94/22418
PCT Pub. Date Oct. 13, 1994

Inventor: HANSENNE ISABELLE (FR)


Patent No.: US 5747530 A Issued: 1998-05- 05

Title: Aromatic dibenzofuran compounds and pharmaceutical/cosmetic compositions comprised thereof

Applicant: CIRD GALDERMA (FR)

Application No.: US1995- 0550335 Applic. Date: 1995-10-30

Abstract: Novel pharmaceutically/cosmetically- active dibenzofuran compounds have the structural formula (I): of the formulae (II) to (VI): [IMAGE] (II) [IMAGE] (III) [IMAGE] (IV) [IMAGE] (V) [IMAGE] (VI) and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

Priority: FR1994-0012989 Applic. Date: 1994-10- 28

Inventor: CHARPENTIER BRUNO (FR); BERNARD BRUNO (FR)


Patent No.: US 5752948 A Issued: 1998-05- 19

Title: Hair removal method

Applicant: THERMOLASE CORP (US)

Application No.: US1995-0492283 Applic. Date: 1995-06-19

Abstract: The present invention provides a process for the destruction of unwanted human hair. Hair ducts in a section of skin in which the unwanted hair are growing is contaminated with a contaminant having a high absorption at at least one frequency band of light. The skin section is then illuminated with light at the frequency band of high absorption so as to impact sufficient energy to the contaminant so as to cause death to the hairs growing in the ducts. In a preferred embodiment the contaminant is a mixture of 1 micron graphite particles in mineral oil and each section is illuminated with about 5 laser pulses at 1.06 micron wavelength produced by a Nd:YAG laser, each pulse having an energy density of about 3 Joules/cm2 and a pulse width of about 10 nanoseconds.; In another preferred embodiment the hairs in the section of skin being treated are pulled out prior to application of the contaminant so as to provide more space for the contaminant in the hair duct. In still another preferred embodiment a portion of the hairs below the skin surface is removed with a depilatory. In still another preferred embodiment C60 molecules, buckey balls, are the absorbing elements in the contaminant.

Priority: US1995- 0492283 Applic. Date: 1995-06-19; US1996-0644231 Applic. Date: 1996-05-13; US1994-0280928 Applic. Date: 1994-07-26; US1993-0005810 Applic. Date: 1993-01-19; US1991-0783789 Applic. Date: 1991-10- 29

Inventor: TANKOVICH NIKOLAI (US); EPISCOPO RICHARD G (US); SVERDRUP LAWRENCE (US)


Patent No.: US 5752949 A Issued: 1998-05-19

Title: Hair removal method

Applicant: THERMOLASE CORP (US)

Application No.: US1996-0644231 Applic. Date: 1996-05- 13

Abstract: A process for the long term or permanent prevention of growth of unwanted hair. The upper portions of hair ducts (i.e. portions near the skin surface) in a section of skin are infiltrated with a contaminant having a high absorption at at least one frequency band of light. The skin is then illuminated using a process having at least two distinct phases. In a "mechanical" phase the skin section is illuminated (e.g., by a laser) with at least one short pulse of light sufficient to cause tiny explosions in the contaminant forcing portions of the contaminant more deeply into the hair ducts. During a "thermal" phase the skin section is then illuminated so as to heat the contaminant substantially without further explosion or vaporization of the contaminant.; The hot contaminant heats portions of the skin tissue immediately surrounding the contaminant to a temperature high enough and for a long enough period of time to devitalize the tissue. The process may also include a "cleanup" phase, during which the skin section is illuminated with a few short pulses of light to cause additional explosions in and vaporization of portions of the contaminant then remaining in the ducts and additional damage to the skin tissue immediately surrounding the contaminant.

Priority: US1996-0644231 Applic. Date: 1996-05-13; US1991-0783789 Applic. Date: 1991-10-29; US1995-0489358 Applic. Date: 1995-06-12; US1995-0492283 Applic. Date: 1995- 06-19; US1994-0280928 Applic. Date: 1994-07-26; US1993-0005810 Applic. Date: 1993-01- 19

Inventor: TANKOVICH NIKOLAI I (US); ZHAO ZHONG-QUAN (US); FAIRCHILD PAUL (US)


Patent No.: US 5753209 A Issued: 1998 -05-19

Title: Photoprotective/cosmetic compositions comprising synergistic admixture of sunscreen compounds

Applicant: SOCIETE L OREAL SA (FR)

Application No.: US1996-0645152 Applic. Date: 1996-05-13

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise a photoprotecting synergistically effective amount of (i) 1,4-benzene [di(3-methylidene-10- camphosulfonic)] acid, optionally either partially or totally neutralized, together with a photoprotecting synergistically effective amount of (ii) a benzotriazole-substituted polyorganosiloxane, in a cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: FR1995- 0005677 Applic. Date: 1995-05-12

Inventor: ASCIONE JEAN-MARC (FR); PISSON ANNE-MARIE (FR)


Patent No.: US 5753241 A Issued: 1998-05-19

Title: Transparent nanoemulsion less than 100 NM based on fluid non-ionic amphiphilic lipids and use in cosmetic or in dermopharmaceuticals

Applicant: OREAL (FR)

Application No.: US1996-0607353 Applic. Date: 1996-02- 26

Abstract: An oil-in-water nanoemulsion in which the oil globules have a mean size of less than 100 nm and which contains an amphiphilic lipid component containing at least one non-ionic amphiphilic lipid which is liquid at an ambient temperature of less than 45 DEG C. The nanoemulsion can be used in the fields of cosmetics and dermopharmaceuticals. The nanoemulsion is stable on storage, can contain significant amounts of oil while retaining good transparency, and can contain heat-sensitive active agents.

Priority: FR1995-0002268 Applic. Date: 1995-02-27

Inventor: RIBIER ALAIN (FR); SIMONNET JEAN-THIERRY (FR); LEGRET SYLVIE (FR)


Patent No.: US 5756110 A Issued: 1998-05- 26

Title: Method for preparing storage-stable, ultrafine oil-in-water emulsion nanopigmented sunscreen/cosmetic compositions

Applicant: OREAL (FR)

Application No.: US1996-0759180 Applic. Date: 1996-12-04

Abstract: Stable and homogeneous, topically applicable sunscreen/cosmetic compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-A and/or UV-B irradiation, particularly solar radiation, and which display excellent transparency on the skin, comprise a storage-stable, ultrafine oil-in-water emulsion of a photoprotecting effective amount of homogeneously and finely dispersed particulates of at least one inorganic nanopigment which comprises a metal oxide, for example titanium dioxide, wherein the average particle size of the globules comprising the oily phase of the emulsion characteristically range from 100 nm to 1,000 nm.

Priority: US1996-0759180 Applic. Date: 1996-12-04; FR1994- 0001455 Applic. Date: 1994-02-09; US1995-0386092 Applic. Date: 1995-02-09

Inventor: ALLARD DELPHINE (FR); ASCIONE JEAN-MARC (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5759563 A Issued: 1998-06- 02

Title: Liquid delivery compositions

Applicant: ATRIX LAB INC (US)

Application No.: US1995-0486262 Applic. Date: 1995-06-07

Abstract: Improved biocompatible liquid delivery compositions, which are useful for the formation of sustained release delivery systems for active agents, are provided. The compositions include liquid formulations of a biocompatible polymer or prepolymer in combination with a controlled release component. The controlled release component includes an active agent. These compositions may be introduced into the body of a subject in liquid form which then solidify or cure in situ to form a controlled release implant or a film dressing. The liquid delivery compositions may also be employed ex situ to produce a controlled release implant. Methods of forming a controlled release implant and employing the liquid formulations in the treatment of a subject are also provided.

Priority: US1995-0486262 Applic. Date: 1995-06-07; US1994-0225140 Applic. Date: 1994-04-08

Inventor: YEWEY GERALD L (US); KRINICK NANCY L (US); DUNN RICHARD L (US); RADOMSKY MICHAEL L (US); BROUWER GERBRAND (US); TIPTON ARTHUR J (US)


Patent No.: US 5762912 A Issued: 1998-06-09

Title: H2O-resistant sunscreen/cosmetic compositions comprising hydrophilic acidic species

Applicant: OREAL (FR)

Application No.: US1995-0425049 Applic. Date: 1995-04-19

Abstract: Improvedly water-resistant sunscreen/cosmetic compositions, well suited for the prolonged UV- photoprotection of human skin and hair, comprise a cosmetically acceptable oil-in-water emulsion containing (i) at least one hydrophilic compound that screens ultraviolet irradiation and which comprises at least one optionally neutralized acid functional group, for example at least one optionally neutralized sulfonic acid or carboxylic acid functional group, and (ii) at least one insoluble filler material that is both inert with respect to said at least one hydrophilic acid compound (i) and an adsorbent therefor.

Priority: FR1994-0004634 Applic. Date: 1994-04- 19

Inventor: ETEVE MARTINE (FR)


Patent No.: US 5772987 A Issued: 1998-06- 30

Title: Photoprotective/cosmetic compositions comprising TiO2 nanopigments and acylamino acids

Applicant: OREAL (FR)

Application No.: US1996-0725494 Applic. Date: 1996-10-04

Abstract: Novel photoprotective/cosmetic photocoloration-resistant compositions, well suited for the photoprotection of human skin and/or hair, comprise an effective UV- screening amount of at least one titanium dioxide nanopigment and an effective photobluing-reducing amount of at least one ionic amphiphilic lipid which comprises an acylamino acid, in a cosmetically acceptable vehicle therefor.

Priority: FR1995-0011662 Applic. Date: 1995-10- 04

Inventor: HANSENNE ISABELLE (FR); LETY ALAIN (FR)


Patent No.: US 5776440 A Issued: 1998-07- 07

Title: Screening cosmetic composition comprising one nanopigment of metallic oxide and one fat-soluble screening polymer

Applicant: OREAL (FR)

Application No.: US1997-0895866 Applic. Date: 1997-07-17

Abstract: The present invention is directed to a composition for screening out ultraviolet radiation, comprising, in association, at least one nanopigment of metallic oxide and at least one UV-screening fat-soluble polymer.

Priority: US1997-0895866 Applic. Date: 1997-07-17; FR1991-0010731 Applic. Date: 1991-08-29; US1993-0039324 Applic. Date: 1993-04-23

Inventor: FORESTIER SERGE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5780044 A Issued: 1998 -07-14

Title: Controlled release delivery compositions

Applicant: ATRIX LAB INC (US)

Application No.: US1996-0761015 Applic. Date: 1996-12- 05

Abstract: Improved biocompatible liquid delivery compositions, which are useful for the formation of sustained release delivery systems for active agents, are provided. The compositions include liquid formulations of a biocompatible polymer or prepolymer in combination with a controlled release component. The controlled release component includes an active agent. These compositions may be introduced into the body of a subject in liquid form which then solidify or cure in situ to form a controlled release implant or a film dressing. The liquid delivery compositions may also be employed ex situ to produce a controlled release implant. Methods of forming a controlled release implant and employing the liquid formulations in the treatment of a subject are also provided.

Priority: US1996-0761015 Applic. Date: 1996-12-05; US1994-0225140 Applic. Date: 1994-04-08

Inventor: YEWEY GERALD L (US); KRINICK NANCY L (US); DUNN RICHARD L (US); RADOMSKY MICHAEL L (US); BROUWER GERBRAND (US); TIPTON ARTHUR J (US)


Patent No.: US 5785979 A Issued: 1998-07- 28

Title: Personal cleansing compositions

Applicant: PROCTER & GAMBLE (US)

Application No.: US1997-0786578 Applic. Date: 1997-01- 21

Abstract: The compositions of the present invention relate to improved personal cleansing compositions comprising a surfactant system, from above about 0.1% to below 1% of a nonionic or anionic water soluble polymer, a phase separation initiator and water. These compositions provide improved lathering and conditioning benefits.

Priority: US1997-0786578 Applic. Date: 1997 -01-21

Inventor: WELLS ROBERT LEE (US)


Patent No.: US 5788955 A Issued: 1998-08- 04

Title: Screening cosmetic composition containing a mixture of 1,4-benzenedi (3- methylidene-10-camphosulfonic) acid, partially or completely neutralized, and metal oxide nanopigments

Applicant: OREAL (FR)

Application No.: US1995-0458192 Applic. Date: 1995-06-02

Abstract: The invention relates to a screening cosmetic composition comprising, in a mixture, 0.5 to 10% by weight of metal oxide nanopigments chosen from titanium, zinc, cerium or zirconium oxide or mixtures thereof, with a mean diameter of less than 100 nm, and 0.1 to 10% by weight of 1,4-benzenedi(3-methylidene-10-camphosulfonic) acid or one of its alkali metal, ammonium, amine, alkanolamine, Ca, Zn, Mg, Ba, Al or Zr salts, in a cosmetically acceptable carrier. This composition is useful as composition for protecting the human epidermis or the hair against UV rays or as make-up.

Priority: US1995-0458192 Applic. Date: 1995-06-02; FR1991 -0007255 Applic. Date: 1991-06-13; US1993-0119651 Applic. Date: 1993-09-13; US1992-0897498 Applic. Date: 1992-06-12

Inventor: ETEVE MARTINE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5795565 A Issued: 1998-08- 18

Title: Screening cosmetic composition containing a mixture of 1,4-benzenedi (3- methylidene-10-camphosulfonic) acid, partially or completely neutralized, and metal oxide nanopigments

Applicant: OREAL (FR)

Application No.: US1997-0822734 Applic. Date: 1997-03-24

Abstract: The invention relates to a screening cosmetic composition comprising, in a mixture, 0.5 to 10% by weight of metal oxide nanopigments chosen from titanium, zinc, cerium or zirconium oxide or mixtures thereof, with a mean diameter of less than 100 nm, and 0.1 to 10% by weight of 1,4-benzenedi(3-methylidene-10-camphosulfonic) acid or one of its alkali metal, ammonium, amine, alkanolamine, Ca, Zn, Mg, Ba, Al or Zr salts, in a cosmetically acceptable carrier. This composition is useful as composition for protecting the human epidermis or the hair against UV rays or as make-up.

Priority: US1997-0822734 Applic. Date: 1997-03-24; FR1991 -0007255 Applic. Date: 1991-06-13; US1993-0119651 Applic. Date: 1993-09-13; US1992-0897498 Applic. Date: 1992-06-12

Inventor: ETEVE MARTINE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5814768 A Issued: 1998-09- 29

Title: Twisted pairs communications cable

Applicant: COMMSCOPE INC (US)

Application No.: US1996-0761981 Applic. Date: 1996-12-11

Abstract: There is disclosed a communications cable having a cable jacket and a first pair of twisted wires disposed within the jacket, each wire thereof having a conductor surrounded by a first insulating material. A second twisted pair of wires is disposed within the jacket and has a twist lay length different from that of the first twisted pair. Each wire of the second twisted pair has a conductor surrounded by an insulating material. The insulating material of the first twisted pair differs in a physical property from the insulating material of the second twisted pair, the physical property of the insulating material of the second pair being correlated with the physical property of the insulating material of the first twisted pair and with differences in twist lay length of the first and second twisted pairs so that the phase delay of the twisted pairs is matched.; There is also provided a communications cable having more than two twisted pairs. The insulating materials include polyolefins such as polyethylene, and fluorinated polymers such as fluorinated ethylene-propylene. The insulating material may be used as either a solid or foamed material covering the conductor. These insulated wires may be used in the transmission of electronic signals in a plenum-rated communications cable.

Priority: US1996-0761981 Applic. Date: 1996-12-11; US1996-0656714P Applic. Date: 1996-06-03

Inventor: WESSELS ROB (US); HAYES TRENT (US)


Patent No.: US 5817089 A Issued: 1998-10- 06

Title: Skin treatment process using laser

Applicant: THERMOLASE CORP (US)

Application No.: US1995-0489358 Applic. Date: 1995-06- 12

Abstract: The present invention provides a very simple easily administered skin treatment process for (1) the removal of superficial epidermal skin cells in the human skin (2) the reduction or removal of unwanted hair and (3) the mitigation of skin conditions such as acne and seborrhea. A contaminant having a high absorption at at least one wavelength of light is topically applied to a section of the surface of the skin. A preferred contaminant is a mixture of 20% by weight of one micron graphite particles in mineral oil. Graphite is a very strong absorber of 1.06 micron light produced by the Nd:YAG laser. Portions of the contaminant are forced to infiltrate into spaces between the superficial epidermal cells, into hair ducts in the skin and into and/or adjacent to sebaceous glands.; The skin section is illuminated with short laser pulses at the matching wavelength, so as to impact sufficient energy to the contaminant to cause explosion in the contaminant. The energy released in the course of the explosions may blow off layers of dead skin cells and/or destroy tissue responsible for hair growth and/or sebum production.

Priority: US1995-0489358 Applic. Date: 1995-06- 12; US1994-0280928 Applic. Date: 1994-07-26; US1994-0257021 Applic. Date: 1994-06-08; US1993-0005810 Applic. Date: 1993-01-19; US1991-0783789 Applic. Date: 1991-10-29

Inventor: TANKOVICH NIKOLAI I (US); SVERDRUP JR LAWRENCE H (US); EPISCOPO RICHARD G (US)


Patent No.: US 5824080 A Issued: 1998-10- 20

Title: Photochemistry for the preparation of biologic grafts-allografts and xenografts

Applicant: GEN HOSPITAL CORP (US)

Application No.: US1996-0708376 Applic. Date: 1996-09-04

Abstract: Photodynamic therapy (PDT), a technique to produce cytotoxic free radicals, was used to prepare arterial allografts. After impregnation with the photo-sensitizer chloroaluminum sulfonated phthalocyanine, aortas of ACI rats were PDT-treated and transplanted in Lewis rats. PDT grafts were completely reendothelialized by 4 weeks.

Priority: US1996-0708376 Applic. Date: 1996-09-04; US1995-0004480P Applic. Date: 1995-09-28

Inventor: LAMURAGLIA GLENN M (US)


Patent No.: US 5833647 A Issued: 1998-11- 10

Title: Hydrogels or lipogels with enhanced mass transfer for transdermal drug delivery

Applicant: PENN STATE RES FOUND (US)

Application No.: US1995- 0541538 Applic. Date: 1995-10-10

Abstract: The present invention comprises a method of transdermal drug delivery where a drug is contained in or must pass through a hydrogel or lipogel together with an enhancement method to improve mass transfer through the skin, the improvement comprising applying a means for enhancing mass transfer of the drug through the hydrogel or lipogel to the skin.

Priority: US1995-0541538 Applic. Date: 1995-10-10

Inventor: EDWARDS DAVID A (US)


Patent No.: US 5843509 A Issued: 1998-12-01

Title: Stabilization of colloidal systems through the formation of lipid-polyssacharide complexes

Applicant: UNIV SANTIAGO COMPOSTELA (ES)

Application No.: US1997-0776507 Applic. Date: 1997-02-27

Abstract: Stabilization of colloidal systems through the formation of lipid-polyssacharide complexes. Development of a procedure for the preparation of colloidal systems involving a combination of two ingredients: a water soluble and positively charged polyssacharide and a negatively charged phospholipid. Colloidal systems (submicron emulsions and polymeric nanoparticles and nanocapsules) are stabilized through the formation, at the interface, of an ionic complex: aminopolyssachride-phospholipid. These colloidal systems are characterized by their positive charge and their improved stability. Furthermore, they can be freeze-dried, stored in a dry state and hydrated when required.; They can be interesting systems for the administration of drugs by the oral, transdermal, ocular, nasal and vaginal routes of administration. In addition, they can be of interest for cosmetic use.

Priority: ES1995- 0001035 Applic. Date: 1995-05-26; WO1996-ES00116 Applic. Date: 1996-05-24

PCT Info:
PCT No. PCT/ES96/00116
Sec 371 Date Feb. 27, 1997
Sec. 102(e) Date Feb. 27, 1997
PCT Filed May 24, 1996
PCT Pub. No. WO96/37232
PCT Pub. Date Nov. 28, 1996

Inventor: CALVO SALVE PILAR (ES); ALONSO FERNANDEZ MARIA JOSE (ES); REMUNAN LOPEZ CARMEN (ES); VILA JATO JOSE LUIS (ES)


Patent No.: US 5849798 A Issued: 1998-12-15

Title: Polyaromatic heterocyclic compounds and pharmaceutical/cosmetic compositions comprised thereof

Applicant: CIRD GALDERMA (FR)

Application No.: US1996-0615843 Applic. Date: 1996-03- 14

Abstract: Novel pharmaceutically/cosmetically-active polyaromatic heterocyclic compounds have the structural formula (I): [IMAGE] (I) in which Z is a divalent radical selected from among -O-, -S- or -Nr'- and Ar is either a radical having the following structural formula (II): [IMAGE] (II) or a radical having the following structural formula (III):nt of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

Priority: FR1995-0002926 Applic. Date: 1995-03- 14

Inventor: CHARPENTIER BRUNO (FR); DIAZ PHILIPPE (FR); NEDONCELLE PHILIPPE (FR)


Patent No.: US 5854225 A Issued: 1998 -12-29

Title: Compounds derived from cyclodextrin

Applicant: OREAL (FR)

Application No.: US1996-0747334 Applic. Date: 1996-11-12

Abstract: The invention relates to cyclodextrin derivatives of formula (I)CD(OH)I(OCOR)m(OR2)n(1)in which each R1 independently denotes a C6-C24 alkyl radical or a C8-C24 alkenyl radical, each R2 independently denotes a C1-C4 alkyl or C2-C4 hydroxyalkyl radical, and I, m and n are statistical values. The invention also relates to a process for the preparation of the compounds of formula (I) and to the use of these compounds in cosmetics.

Priority: FR1995-0013413 Applic. Date: 1995-11- 13

Inventor: RICHARD HERVE (FR); LEDUC MADELEINE (FR)


Patent No.: US 5858334 A Issued: 1999-01- 12

Title: Artificial tanning compositions comprising dihydroxyacetone

Applicant: SOCIETEL OREAL S A (FR)

Application No.: US1997 -0794063 Applic. Date: 1997-02-04

Abstract: Stable and homogeneous, topically applicable cosmetic compositions well suited for artificially tanning human skin, comprise a storage- stable, ultrafine oil-in-water emulsion, devoid of lipid vesicles, containing an effective artificial tanning amount of dihydroxyacetone, and further wherein the average particle size of the globules comprising the oily phase of the emulsion characteristically ranges from 100 nm to 1,000 nm.

Priority: US1997-0794063 Applic. Date: 1997-02-04; FR1994-0002254 Applic. Date: 1994 -02-28; US1995-0395925 Applic. Date: 1995-02-28

Inventor: ASCIONE JEAN-MARC (FR); ALLARD DELPHINE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5863522 A Issued: 1999-01-26

Title: Screening cosmetic composition comprising one nanopigment of metallic oxide and one fat-soluble screening polymer

Applicant: OREAL (FR)

Application No.: US1997-0895865 Applic. Date: 1997-07-17

Abstract: The present invention is directed to a composition for screening out ultraviolet radiation, comprising, in association, at least one nanopigment of metallic oxide and at least one UV-screening fat-soluble polymer.

Priority: US1997-0895865 Applic. Date: 1997-07-17; FR1991-0010731 Applic. Date: 1991-08-29; WO1992-FR00821 Applic. Date: 1992-08-25; US1993-0039324 Applic. Date: 1993-04-23

Inventor: FORESTIER SERGE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5866148 A Issued: 1999-02-02

Title: Photoprotective compositions comprising mutually incompatible oily dispersed phases

Applicant: SOCIETEL OREAL S A (FR)

Application No.: US1997-0880739 Applic. Date: 1997-06-23

Abstract: Topically applicable, water resistant cosmetic/dermatological compositions well suited for enhanced photoprotection of human skin and or/hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (I) a continuous aqueous dispersing phase, (ii) a first discontinuous globular oily dispersed phase O1, (iii) a second discontinuous globular oily dispersed phase O2, (iv) at least one O/W emulsifying agent, (v) at least one W/O emulsifying agent, (vi) a photoprotecting effective amount of at least one lipophilic UV screening agent, (vii) a photoprotecting effective amount of at least one hydrophilic screening agent, said first and second oily phases O1 and O2 being mutually incompatible, and the globules constituting said oily phase O1 having an average size which is different from the globules constituting said oily phase O2.

Priority: FR1996- 0007775 Applic. Date: 1996-06-21

Inventor: HANSENNE ISABELLE (FR); DE CHABANNES KARINE (FR); VERNAIRE SANDRINE (FR)


Patent No.: US 5885274 A Issued: 1999-03-23

Title: Filament lamp for dermatological treatment

Applicant: NEW STAR LASERS INC (US)

Application No.: US1997-0881539 Applic. Date: 1997-06-24

Abstract: Thermal modification of dermatological tissue using non-laser infrared light energy. A high energy incandescent-type lamp, such as a quartz tungsten halogen lamp, operated in a pulsed mode with a high voltage input, creates a particular energy output. Applications of such apparatus and methods include treatment of the dermis and/or sub-epidermal tissues for the purpose of skin recontouring, thermal destruction of hair follicles for the purpose of hair removal, and others.

Priority: US1997-0881539 Applic. Date: 1997- 06-24

Inventor: FULLMER DAVID J (US); HENNINGS DAVID R (US); SAND BRUCE J (US)


Patent No.: US 5899865 A Issued: 1999 -05-04

Title: Localization of abnormal breast tissue using time-resolved spectroscopy

Applicant: NON INVASIVE TECHNOLOGY INC (US)

Application No.: US1995-0484982 Applic. Date: 1995-06-07

Abstract: A method of breast tissue examination using time-resolved spectroscopy includes the following steps. A support that includes an input port and an output port separated by a selected distance is positioned relative to the examined breast. Locations of the input and output ports are selected to examine a tissue region of the breast. Light pulses of a selected wavelength and duration less than a nanosecond are introduced into the breast tissue at the input port and detected over time at the detection port. Signals corresponding to photons of detected modified pulses are accumulated over time. Values of a scattering coefficient or an absorption coefficient of the examined breast tissue are calculated based on the shape of the modified pulses. The examined breast tissue is characterized based on the values of the scattering coefficient or the absorption coefficient.; Absorbing or fluorescing contrast agents may be introduced into the examined tissue. This method may be used in conjunction with x-ray mammography, needle localization procedure or MRI mammography.

Priority: US1995-0484982 Applic. Date: 1995-06-07; US1993- 0093208 Applic. Date: 1993-07-16; US1993-0040168 Applic. Date: 1993-03-30; US1992-0876364 Applic. Date: 1992-04-30; US1988-0287847 Applic. Date: 1988-12-21

Inventor: CHANCE BRITTON (US)


Patent No.: US 5905088 A Issued: 1999-05-18

Title: Heterocyclic biaryl compounds and pharmaceutical/cosmetic compositions comprised thereof

Applicant: CIRD GALDERMA (FR)

Application No.: US1997-0886039 Applic. Date: 1997-06-30

Abstract: Novel pharmaceutically/cosmetically-active heterocyclic biaryl compounds have the structural formula (I): wherein Ar is a radical having one of the formulae (a)-(h): and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for cosmetic applications and for the treatment of mammalian skin and hair conditions/disorders.

Priority: FR1996-0008115 Applic. Date: 1996-06-28

Inventor: DIAZ PHILIPPE (FR); THOREAU ETIENNE (FR)


Patent No.: US 5910508 A Issued: 1999 -06-08

Title: Polycyclic polyenic compounds and pharmaceutical/cosmetic compositions comprised thereof

Applicant: CIRD GALDERMA (FR)

Application No.: US1997- 0921591 Applic. Date: 1997-09-02

Abstract: Novel pharmaceutically/cosmetically- active polycyclic polyenic compounds have the structural formula (I): and are useful for modulating cellular hormone receptors.

Priority: FR1996-0010686 Applic. Date: 1996-09- 02

Inventor: THOREAU ETIENNE (FR); SHROOT BRAHAM (FR)


Patent No.: US 5919487 A Issued: 1999-07- 06

Title: Nanoparticles coated with a lamellar phase based on silicone surfactant and compositions containing them

Applicant: OREAL (FR)

Application No.: US1996- 0771837 Applic. Date: 1996-12-23

Abstract: The present invention relates to nanoparticles, and in particular nanocapsules, provided with a lamellar coating obtained from a silicone surfactant, and to their use in a composition, in particular a topical composition, for treatment of the skin, mucosae, nails, scalp and/or hair.

Priority: FR1995-0015293 Applic. Date: 1995-12- 21

Inventor: SIMONNET JEAN-THIERRY (FR); RICHART PASCAL (FR)


Patent No.: US 5925035 A Issued: 1999-07- 20

Title: Hair removal method

Applicant: THERMOLASE CORP (US)

Application No.: US1996-0695200 Applic. Date: 1996-08-01

Abstract: A process for the permanent destruction of unwanted human hair. Hair duct in a section of skin in which the unwanted hair is growing is contaminated with a contaminant having a very large number of small particles having a high absorption at at least one frequency band of light. The skin section is then illuminated with a series of short pulses of light at the frequency band of high absorption, the first of the short pulses having sufficient energy to cause a large number of the particles to explode into two or more fragments so as to spread said contaminant in the hair ducts and subsequent pulses having sufficient energy to cause a large number of the fragments to further explode into additional fragments to further spread the contaminant in the hair duct.; The explosions and energy is transferred to and from the particles and fragments causing damage to skin tissue surrounding said hair ducts so as to cause death to the hairs growing in the ducts. In a preferred embodiment the particles are 1 micron graphite particles and each section is illuminated with about 5 laser pulses at 1.06 micron wavelength produced by a Nd:YAG laser, each pulse having an energy density of about 3 Joules/cm2 and a pulse width of about 10 nano seconds.

Priority: US1996-0695200 Applic. Date: 1996-08-01; US1994- 0280928 Applic. Date: 1994-07-26; US1994-0257021 Applic. Date: 1994-06-08; US1993-0005810 Applic. Date: 1993-01-19; US1991-0783789 Applic. Date: 1991-10-29

Inventor: TANKOVICH NIKOLAI I (US)


Patent No.: US 5925364 A Issued: 1999-07-20

Title: Cosmetic or dermatological composition comprising an oil -in-water emulsion comprising oily globules with a lamellar liquid crystal coating

Applicant: OREAL (FR)

Application No.: US1995-0540165 Applic. Date: 1995-10-06

Abstract: The present invention relates to a cosmetic or dermatological composition comprising an emulsion of oil-in-water type formed of oily globules which are each provided with a lamellar liquid crystal coating and are dispersed in an aqueous phase. Each oily globule containing at least one lipophilic compound which is cosmetically or dermatologically active is individually coated with a monolamellar or aligolamellar layer obtained from at least one lipophilic surface-active agent, from at least one hydrophilic surface-active agent and from at least one ionic amphiphilic lipid imparting to the emulsion a pH ranging from 5.5 to 7.5, the coated oily globules having a mean diameter of less than 500 nanometers.

Priority: FR1994-0012005 Applic. Date: 1994-10-07

Inventor: RIBIER ALAIN (FR); SIMONNET JEAN-THIERRY (FR); MICHELET JACQUES (FR)


Patent No.: US 5928630 A Issued: 1999-07-27

Title: Benzalmalonate/phenylcyanoacrylate-substituted s-triazine compounds and photoprotective/cosmetic compositions comprised thereof

Applicant: OREAL (FR)

Application No.: US1998-0148497 Applic. Date: 1998-09- 04

Abstract: Photoprotective/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair, as well as of a wide variety of other photosensitive materials and substrates, e.g., inorganic or organic glasses, plastics or the like, against the deleterious effects of UV-A and UV-B irradiation, particularly solar radiation, comprise a photoprotecting effective amount of a novel insoluble benzalmalonate/phenylcyanoacrylate-substituted s- triazine compound having the structural formula (I): in which R1, R1' and R1'', which may be identical or different, are each a monovalent radical having one of the formulae (A) or (B) below:

Priority: US1998-0148497 Applic. Date: 1998-09-04; US1997-0798136 Applic. Date: 1997-02-12; FR1996-0001692 Applic. Date: 1996-02-12

Inventor: RICHARD HERVE (FR); LEDUC MADELEINE (FR); LAGRANGE ALAIN (FR); PLESSIX HERVE (FR)


Patent No.: US 5932194 A Issued: 1999-08- 03

Title: UV-Photoprotective cosmetic compositions comprising polymer particulates/fatty phases having unique refractive indices

Applicant: OREAL (FR)

Application No.: US1998-0034229 Applic. Date: 1998-03-04

Abstract: Topically applicable cosmetic/dermatological composition well suited for improved photoprotection of human keratinous substrates, for example human skin and/or hair, comprise (a) an aqueous phase, (b) at least one fatty phase having a refractive index n1, (c) an effective UV-photoprotecting amount of at least one water- soluble UV-screening active agent, and (d) particulates of at least one non-film- forming polymer having a refractive index n2, and the refractive indices n1, and n2 being selected such that: ¦n2- n1¦[/=0.07.

Priority: FR1997-0002800 Applic. Date: 1997-03-10

Inventor: PLESSIX HERVE (FR); MONDET JEAN (FR); DE RIGAL JEAN (FR)


Patent No.: US 5939053 A Issued: 1999-08- 17

Title: Screening cosmetic composition comprising one nanopigment of metallic oxide and one fat-soluble screening polymer

Applicant: OREAL (FR)

Application No.: US1997-0896428 Applic. Date: 1997-07-17

Abstract: The present invention is directed to a composition for screening out ultraviolet radiation, comprising, in association, at least one nanopigment of metallic oxide and at least one UV-screening fat-soluble polymer.

Priority: FR1991-0010731 Applic. Date: 1991-08-29

Inventor: FORESTIER SERGE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5939079 A Issued: 1999-08-17

Title: Process for the dispersion by high-pressure homogenization of pulverulent fillers in a vehicle composed of at least one fatty phase, compositions obtained and uses

Applicant: OREAL (FR)

Application No.: US1997-0778348 Applic. Date: 1997-01-03

Abstract: The present invention relates to a process for the dispersion of at least one pulverulent organic filler and/or of at least one pulverulent inorganic filler in a vehicle composed of at least one fatty phase, by mixing the filler or fillers in the vehicle by high-pressure homogenization in one or a number of passes, to the cosmetic or dermatological compositions capable of being obtained by this process. The present invention also relates to the use of the compositions obtained by this process as the basis for care, make-up and/or hygiene products. The present invention also relates to the use of the compositions obtained by this process as the basis for products for protecting the skin, hair, scalp, nails, eyelashes, eyebrows and/or mucous membranes against the effects of ultraviolet radiation.

Priority: FR1996-0000029 Applic. Date: 1996 -01-03

Inventor: LE ROYER ISABELLE (FR); THIBAUT CATHERINE (FR)


Patent No.: US 5942531 A Issued: 1999-08- 24

Title: Phenolic/naphtholic retinoids for promoting skin/exoskeleton pigmentation

Applicant: CIRD (FR)

Application No.: US1998-0021396 Applic. Date: 1998-02-10

Abstract: Pigmentation of the skin, hair and/or nails of individuals is promoted by administering thereto, advantageously topically and advantageously in combination with enzymes exhibiting tyrosinase activity, effective pigmentation-promoting amounts of at least one retinoid compound which comprises a phenolic or naphtholic functional group.

Priority: FR1997-0001500 Applic. Date: 1997-02-10

Inventor: DIAZ PHILIPPE (FR); CHARPENTIER BRUNO (FR); SHROOT BRAHAM (FR)


Patent No.: US 5947906 A Issued: 1999-09-07

Title: Apparatus for enhanced visual venous examination

Application No.: US1997-0970466 Applic. Date: 1997-11- 14

Abstract: An apparatus for aiding in performing operations requiring location of blood vessels such as intravenous injections or drawing blood in which a charge coupled device camera is focused on an area of the body such as the arm that is illuminated by a light source which emits light that is partly in the infrared range and partly in the ultraviolet range but from which light light having a wavelength in the visible range has been substantially eliminated. The useful range of wavelengths may be provided by any one of several methods including having an infrared source and an ultra violet source or an incandescent source emitting wavelengths extending from the infrared to the ultra violet and having a filter for removing the range of visible light.

Priority: US1997-0970466 Applic. Date: 1997-11-14

Inventor: DAWSON JR FREDRIC O (US); ESPARZA JOEL (US)


Patent No.: US 5951968 A Issued: 1999-09-14

Title: UV-photoprotective dibenzoylmethane compositions comprising photostabilizing amounts of benzalmalonate silanes

Applicant: OREAL (FR)

Application No.: US1998-0035758 Applic. Date: 1998-03-06

Abstract: Topically applicable, stable, UV-photoprotective cosmetic/dermatological compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, comprise (a) an effective UV-photoprotecting amount of at least one dibenzoylmethane UV-sunscreen compound and (b) an effective dibenzoylmethane compound (a) photostabilizing amount of at least one benzalmalonate silane having the structural formula (I):

Priority: FR1997-0002759 Applic. Date: 1997-03-07

Inventor: FORESTIER SERGE (FR); RICHARD HERVE (FR); ALLARD DELPHINE (FR); CANDAU DIDIER (FR)


Patent No.: US 5952040 A Issued: 1999-09-14

Title: Passive electronic components from nano- precision engineered materials

Applicant: NANOMATERIALS RESEARCH CORP (US)

Application No.: US1996-0730661 Applic. Date: 1996-10-11

Abstract: Nanosize powders with particle size smaller than the critical length for specific material properties are used to form the ceramic layers of passive electronic components. Ceramic substrates are coated with electrodes, which are then coated with a ceramic layer from a suspension, preferably a low viscosity suspension, of nanoscale powders. The ceramic layer is dried at low temperatures (preferably below 200 DEG C.) and it is sintered to high density (preferably above 90%) at moderate temperatures (preferably low and less than 1,000 DEG C.). Once sintered, an electrode layer is coated on top of the ceramic layer to yield an electrode/ceramic/electrode structure.

Priority: US1996-0730661 Applic. Date: 1996-10-11

Inventor: YADAV TAPESH (US); YANG MARK L (US)


Patent No.: US 5952382 A Issued: 1999-09- 14

Title: Adamantyl-substituted retinoids and pharmaceutical/cosmetic compositions comprised thereof

Applicant: CIRD GALDERMA (FR)

Application No.: US1996- 0642424 Applic. Date: 1996-05-03

Abstract: Pharmaceutically/cosmetically-active adamantyl-substituted retinoid compounds have the structural formula (I): wherein Ar is a radical having one of the formula (a) - (d): and are useful for the treatment of disorders and/or ailments manifesting an overregulation of RAR receptors and/or a hypervitaminosis A.

Priority: FR1995-0005279 Applic. Date: 1995-05-03

Inventor: BERNARDON JEAN-MICHEL (FR)


Patent No.: US 5954685 A Issued: 1999-09- 21

Title: Electrochemical sensor with dual purpose electrode

Applicant: CYGNUS THERAPEUTIC SYSTEMS (US)

Application No.: US1996-0653161 Applic. Date: 1996 -05-24

Abstract: The present invention provides an electrode assembly for use in a transdermal analyte sensor operating in an alternating polarity mode in which a single electrode element provides both the counter electrode and iontophoretic electrode functions. By combining both the functions of the iontophoretic and counter electrode, the surface area of the electrode with respect to each function may be made larger. In turn this increases the ability of the electrode to deliver the required electrical field over a larger area when operating in the iontophoretic mode as well as increasing the ability of the counter electrode to compensate for the larger sensing electrode facilitated by this new design.

Priority: US1996-0653161 Applic. Date: 1996-05- 24

Inventor: TIERNEY MICHAEL J (US)


Patent No.: US 5955091 A Issued: 1999-09- 21

Title: Photobluing/whitening-resistant cosmetic/dermatological compositions comprising TiO2 pigments and deformable hollow particulates

Applicant: SOCIETEL OREAL S A (FR)

Application No.: US1996-0679806 Applic. Date: 1996-07-15

Abstract: Topically applicable cosmetic/sunscreen/dermatological compositions, well suited for improved photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation and/or for the therapeutic treatment of a disease state of the skin or mucosae, essentially in the absence of photobluing/whitening, comprise at least one titanium dioxide (nano)pigment and an effective photobluing/whitening-reducing amount of deformable hollow particulates (microspheres) having a particle size ranging from 1 mu m to 250 mu m and which comprise an expanded copolymer of vinylidene chloride, acrylonitrile and a (meth)acrylate.

Priority: FR1995-0008564 Applic. Date: 1995-07-13; FR1995-0008565 Applic. Date: 1995-07-13

Inventor: HANSENNE ISABELLE (FR)


Patent No.: US 5961469 A Issued: 1999-10- 05

Title: Spectrophotometric assay for cyanide

Application No.: US1996- 0749032 Applic. Date: 1996-11-14

Abstract: A method of detecting and quantifying cyanide concentration in a patient, by monitoring photometric changes resulting from the transformation of methemoglobin to cyanomethemoglobin. The present invention provides for a means of cyanide poisoning assessment in patients using the affinity of methemoglobin for cyanide to assess the photometric changes resulting from methemoglobin converting to cyanomethemoglobin, as an indicator of cyanide concentration in a patient. Appropriate corrective action can then be promptly taken.

Priority: US1996- 0749032 Applic. Date: 1996-11-14; US1995-0007397P Applic. Date: 1995-11-21

Inventor: ROIZEN MICHAEL F (US); MOSS JON (US)


Patent No.: US 5965115 A Issued: 1999-10-12

Title: Personal care compositions

Applicant: PROCTER & GAMBLE (US)

Application No.: US1997- 0964803 Applic. Date: 1997-11-05

Abstract: Disclosed are personal care compositions which are suitable for application to the hair, skin, or nails. These compositions comprise a polyorganosiloxane emulsion comprising a surfactant and a polyorganosiloxane having an average particle size of less than about 150 nanometers; from about 0.01% to about 10% of a silicone-linear polyoxyalkylene block copolymer surfactant; and a carrier comprising (i) at least about 0.5%, by weight of the composition, of a first solvent selected from the group consisting of water, water soluble organic solvents, organic solvents which are strongly to moderately strong in hydrogen-bonding parameter, and mixtures thereof, wherein the solvent is other than a C1-C3 monohydric alcohol, a C1-C3 ketone, and a C1-C3 ether, and (ii) at least about 40%, by weight of the composition, of a second solvent selected from the group consisting of C1-C3 monohydric alcohols, C1-C3 ketones, C1-C3 ethers, and mixtures thereof. The silicone-polyoxyalkylene copolymer surfactant provides for improved stability of the polyorganosiloxane emulsion, especially when lower alcohols such as C1-C3 monohydric alcohols are incorporated into the compositions.

Priority: US1997-0964803 Applic. Date: 1997-11- 05

Inventor: BOLICH JR RAYMOND EDWARD (US); RIGNEY KENNETH WAYNE (US)


Patent No.: US 5968034 A Issued: 1999-10- 19

Title: Pulsed filament lamp for dermatological treatment

Applicant: LASER AESTHETICS INC (US)

Application No.: US1998-0103756 Applic. Date: 1998-06- 24

Abstract: A high energy filament lamp light source, such as a quartz tungsten halogen lamp, operated in a pulsed mode with a high voltage input, creates a particular energy output. Applications of such apparatus and methods include treatment of the dermis and/or sub-epidermal tissues for the purpose of skin recontouring, thermal destruction of hair follicles for the purpose of hair removal, and others, and a method which selectively preheats a subsurface region in targeted tissue to sub-thermal modification threshold values without significant heat damage to surrounding layers prior to further treatment.

Priority: US1998-0103756 Applic. Date: 1998-06-24; US1997-0881539 Applic. Date: 1997-06-24

Inventor: FULLMER DAVID J (US); HENNINGS DAVID R (US); SAND BRUCE J (US)


Patent No.: US 5968481 A Issued: 1999-10-19

Title: Photoprotective/cosmetic compositions comprising synergistic admixture of sunscreen compounds

Applicant: SOCIETEL OREAL S A (FR)

Application No.: US1995-0463507 Applic. Date: 1995-06-05

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise a photoprotecting synergistically effective amount of (i) 2,4,6-tris[p-((2'- ethylhexyl)oxycarbonyl)anilino]-1,3,5-triazine and (ii) 2-ethylhexyl alpha -cyano- beta , beta - diphenylacrylate, in a cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: FR1994-0006828 Applic. Date: 1994-06-03

Inventor: ASCIONE JEAN-MARC (FR); ALLARD DELPHINE (FR)


Patent No.: US 5972313 A Issued: 1999-10- 26

Title: Active/stable artificial tanning compositions comprising DHA derivatives

Applicant: OREAL (FR)

Application No.: US1997-0819084 Applic. Date: 1997-03-18

Abstract: Stable, topically applicable cosmetic/dermatological compositions well suited for artificially tanning or browning human skin and appropriately packaged, comprise at least one dihydroxyacetone (DHA) derivative convertible into DHA and, advantageously, at least one active species for effecting such conversion.

Priority: FR1996-0003344 Applic. Date: 1996-03-18

Inventor: TULOUP REMY (FR); BLAISE CHRISTIAN (FR); PHILIPPE MICHEL (FR); SERA DANIEL (FR); DE SALVERT ARMELLE (FR)


Patent No.: US 5973007 A Issued: 1999-10- 26

Title: Use of inhibitors of retinoic acid activity for wound healing

Applicant: CIRD GALDERMA (FR)

Application No.: US1998-0068956 Applic. Date: 1998-07-28

Abstract: A method for promoting healing by administration of an inhibitor of the activity of retinoic acid is provided. Preferred compounds for use in such treatment include antagonists of retinoic acid. The method is particularly applicable for promoting skin healing and treatment of surgical and traumatic wounds.

Priority: FR1996-0011511 Applic. Date: 1996-09-20; WO1997-FR01641 Applic. Date: 1997-09-17

PCT Info:
PCT No. PCT/FR97/01641
Sec 371 Date Jul. 28, 1998
Sec. 102(e) Date Jul. 28, 1998
PCT Filed Sep. 17, 1997
PCT Pub. No. WO98/11886
PCT Pub. Date Mar. 26, 1998

Inventor: DEMARCHEZ MICHEL (FR); ROSSIO PATRICIA (FR); JOMARD ANDRE (FR)


Patent No.: US 5973784 A Issued: 1999-10- 26

Title: Common path, interferometric systems and methods using a birefringent material for topographic imaging

Applicant: ELECTRO OPTICAL SCIENCES INC (US)

Application No.: US1998-0004560 Applic. Date: 1998-01-08

Abstract: Common path, two beam interferometers and interferometric measurement systems employ a voltage controlled variable phase retarder enabling rapid stepping of the relative phase between two interfering optical beams by suitable control of the voltage. The beams need not be laterally separated. A compact beam expander with a ball lens is preferably included. The system is compact enough to be contained in a hand-held unit. The system can be used for surface mapping, testing of optical components and detecting the motion of mechanical objects, for example. It is particularly well suited for the mapping of the skin of a live subject. An optimum fringe period and optimum illumination wavelengths for imaging skin are disclosed, enabling the topography of substantial areas of human skin to be rapidly and accurately measured, in times on the order of one-tenth of a second.; Methods of conducting interferometric analysis are disclosed, as well.

Priority: US1998-0004560 Applic. Date: 1998-01-08; US1997-0786140 Applic. Date: 1997-01-21; US1997-0780336 Applic. Date: 1997-01-08

Inventor: SZWAYKOWSKI PIOTR (US); GREENEBAUM MICHAEL (US); SHULTZ THEODORE S (US)


Patent No.: US 5985925 A Issued: 1999-11- 16

Title: Photoprotective/cosmetic compositions comprising UV-sunscreens/dialkyl tartrates

Applicant: OREAL (FR)

Application No.: US1998-0149764 Applic. Date: 1998-09-09

Abstract: Novel cosmetic/dermatological UV-photoprotective compositions well suited for enhanced PF photoprotection of human skin and/or hair comprise (a) an effective UV-screening amount of at least one benzylidenecamphor sunscreen compound, and/or at least one dibenzoylmethane sunscreen compound, and/or at least one triazine sunscreen compound, and (b) a PF- enhancing amount of at least one dialkyl tartrate, formulated into a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.

Priority: FR1997-0011173 Applic. Date: 1997-09-09

Inventor: JOSSO MARTIN (FR); REFREGIER JEAN-LOUIS (FR); HANSENNE ISABELLE (FR)


Patent No.: US 5989409 A Issued: 1999-11-23

Title: Method for glucose sensing

Applicant: CYGNUS THERAPEUTIC SYSTEMS (US)

Application No.: US1995- 0526732 Applic. Date: 1995-09-11

Abstract: A method for measuring the concentration of glucose diffused from a source to a working electrode which assembly includes a scavenging electrode is disclosed. The electrode of the invention is comprised of 1) a working electrode; 2) a scavenging electrode; 3) an electroosmotic electrode; and 4) a electrically insulating gap defined by adjacent edges of 1) and 2) and electrically isolating 1) and 2). The scavenging electrode substantially reduces or eliminates "edge-effects" or error in signal transported to the working electrode via a path which includes a radial vector component, i.e., eliminates chemical signal other than that which moves to the catalytic surface of the working electrode via a path which is substantially perpendicular to catalytic surface of the working electrode.

Priority: US1995-0526732 Applic. Date: 1995-09-11

Inventor: KURNIK RONALD T (US); TAMADA JANET (US); TIERNEY MICHAEL (US)


Patent No.: US 5993831 A Issued: 1999-11-30

Title: Composition providing a lasting cosmetic and/or pharmaceutical treatment of the upper epidermal layers by topical application on the skin

Applicant: OREAL (FR)

Application No.: US1993-0050315 Applic. Date: 1993-05-10

Abstract: A composition containing, in a suitable carrier, nanoparticles of one or more nonbiodegradable polymer(s) encapsulating an oily phase which contains at least one active oil and/or at least one carrier oil and/or at least one active ingredient in an active oil and/or a carrier oil. At least one active ingredient is chosen from those with prolonged cosmetic and/or pharmaceutical activity. The nanocapsules have a size of 100-1000 nm.

Priority: FR1991-0011344 Applic. Date: 1991-09-13; WO1992-FR00824 Applic. Date: 1992-08-27

PCT Info:
PCT No. PCT/FR92/00824
Sec 371 Date May 18, 1993
Sec. 102(e) Date May 18, 1993
PCT Filed Aug. 27, 1992
PCT Pub. No. WO93/05753
PCT Pub. Date Apr. 1, 1993

Inventor: RIBIER ALAIN (FR); RICHART PASCAL (FR); HANDJANI ROSE-MARIE (FR)


Patent No.: US 5993854 A Issued: 1999 -11-30

Title: Exothermic effervescent composition for improved fragrance dispersion

Applicant: PHYZZ INC (US)

Application No.: US1998-0007959 Applic. Date: 1998-01-16

Abstract: An aroma releasing composition has an effervescent agent, an exothermic agent and a volatile agent, the effervescent agent and exothermic agent provided in a ratio sufficient to promote release of the volatile agent, when the composition is placed in water. Such a composition has use, alone, in promoting release of fragrance agents, or in combination with a product, such as a body lotion, shampoo or liquid soap.

Priority: US1998-0007959 Applic. Date: 1998-01-16; US1997-0059198P Applic. Date: 1997-09- 17

Inventor: NEEDLEMAN NORMAN (US); RAU ALLEN (US)


Patent No.: US 5997888 A Issued: 1999-12- 07

Title: Cosmetic preparations

Applicant: VESIFACT AG (CH)

Application No.: US1997-0989763 Applic. Date: 1997-12-12

Abstract: The cosmetic preparation contains: (a) an oil-soluble active ingredient that is suitable for skin cosmetics, (b) a partial fatty acid ester of polyoxyethylene sorbitan, (c) at least one phospholipid, (d) ethanol, and (e) water as a carrier liquid. The phospholipid is dissolved in ethanol, and then the partial fatty acid esters of polyoxyethylene sorbitan and the active ingredient are added. The oil phase that is obtained is added to water and stirred. The preparation is obtained in the form of a nanodispersion.

Priority: CH1996-0003065 Applic. Date: 1996-12-13

Inventor: WEDER HANS GEORG (CH); WEDER MARC ANTOINE (CH)


Patent No.: US 6011067 A Issued: 2000-01- 04

Title: Antioxidant composition for the treatment of psoriasis and related diseases

Applicant: THIONE INTERNATIONAL INC (US)

Application No.: US1999- 0329849 Applic. Date: 1999-06-11

Abstract: The present invention deals with the combination of several synergistic antioxidants including enzymatic co-factors as adjuncts to therapy of desquamating inflammatory disorders, such as psoriasis. These topical compositions are aimed to neutralize free radical species generated by such inflammatory conditions which are responsible for certain clinical signs and symptoms. As such, damage to skin causing destruction of elastin and collagen tissues is reduced. The present synergistic antioxidants may be combined with anti-inflammatories, including corticosteroids, anti-microbials, including zinc pyrithione, and other preparations useful in the therapy of desquamating disorders as psoriasis, seborrhoeic dermatitis and related skin and scalp conditions.

Priority: US1999-0329849 Applic. Date: 1999-06-11

Inventor: HERSH THEODORE (US)


Patent No.: US 6013247 A Issued: 2000-01-11

Title: Composition for protecting the skin or the hair, containing nanopigments and a solid elastomeric polyorganosiloxane combined with a fatty phase

Applicant: OREAL (FR)

Application No.: US1997-0905782 Applic. Date: 1997-07-29

Abstract: A composition for topical application containing nanopigments and a solid elastomeric polyorganosiloxane combined with a fatty phase, in order to improve the protection factor provided by the nanopigments and stabilize the composition.

Priority: FR1996-0009525 Applic. Date: 1996-07-29

Inventor: BARA ISABELLE (FR); LEMANN PATRICIA (FR)


Patent No.: US 6019482 A Issued: 2000-02- 01

Title: Polychromatic body surface irradiator

Application No.: US1998- 0173022 Applic. Date: 1998-10-15

Abstract: A hand-held, self-contained irradiator is powered by batteries. At an applicator end are provided many diodes that emit electromagnetic radiation in the visible and/or infrared portions of the spectrum. A series of switches are provided so that the user may select which one or ones of the diodes to activate to provide particular wavelengths or colors of radiation to be emitted from the applicator end to be used to treat particular body surface areas for the relief of pain or other problems. An optional line cord powered embodiment is also disclosed.

Priority: US1998-0173022 Applic. Date: 1998-10-15

Inventor: EVERETT RANDALL L (US)


Patent No.: US 6024944 A Issued: 2000-02-15

Title: Antisan composition containing a solid elastomeric organopolysiloxane

Applicant: OREAL (FR)

Application No.: US1999-0171433 Applic. Date: 1999-01-28

Abstract: The invention relates to an antisun composition with a high degree of protection, containing water-soluble and liposoluble screening agents, combined with a solid elastomeric organopolysiloxane, which has noteworthy cosmetic properties. It is in the form of a water-in-oil or oil-in-water emulsion. The invention also relates to a process for protecting the skin or the lips against solar radiation, containing this composition.

Priority: FR1997-0001811 Applic. Date: 1997-02-17; WO1998-FR00191 Applic. Date: 1998-02-03

PCT Info:
PCT No. PCT/FR98/00191
Sec 371 Date Jan. 28, 1999
Sec. 102(e) Date Jan. 28, 1999
PCT Filed Feb. 3, 1998
PCT Pub. No. WO98/35649
PCT Pub. Date Aug. 20, 1998

Inventor: HANSENNE ISABELLE (FR)


Patent No.: US 6030378 A Issued: 2000-02- 29

Title: Method of hair removal by transcutaneous application of laser light

Application No.: US1998-0084294 Applic. Date: 1998-05- 26

Abstract: A method of hair removal, used primarily for cosmetic purposes, comprising the transcutaneous use of laser light having a wavelength which targets the sebum found in the follicle and coating the hair, heating the sebum which transfer heat first to the hair and hair root and then to the papilla and papillary blood vessels via conduction, thus destroying the hair by photothermolysis while avoiding significant damage to surrounding skin or tissue.

Priority: US1998-0084294 Applic. Date: 1998-05-26

Inventor: STEWART BOB W (US)


Patent No.: US 6033648 A Issued: 2000-03- 07

Title: Artificial tanning compositions comprising iron oxide nanopigments

Applicant: OREAL (FR)

Application No.: US1999-0344354 Applic. Date: 1999-06-25

Abstract: Topically applicable cosmetic/dermatological compositions well suited for the persistent and water-resistant artificial tanning and/or darkening of human skin, comprise an effective artificial tanning/darkening amount of particulates of at least one iron oxide nanopigment, the mean size of the primary particles of which nanopigment particulates being less than 100 nm, the particulates of the at least one iron oxide nanopigment being formulated into a vehicle, diluent or carrier therefor which comprises a water-in-oil emulsion, advantageously a water-in -silicone emulsion, and the particulates comprising greater than 2% by weight of the total weight of such cosmetic/dermatological compositions.

Priority: FR1998-0008164 Applic. Date: 1998-06 -26

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6036684 A Issued: 2000-03- 14

Title: Skin treatment process using laser

Applicant: THERMOLASE CORP (US)

Application No.: US1998-0168202 Applic. Date: 1998-10- 06

Abstract: The present invention provides a very simple easily administered skin treatment process for (1) the removal of superficial epidermal skin cells in the human skin (2) the reduction or removal of unwanted hair and (3) the mitigation of skin conditions such as acne and seborrhea. A contaminant having a high absorption at at least one wavelength of light is topically applied to a section of the surface of the skin. A preferred contaminant is a mixture of 20% by weight of one micron graphite particles in mineral oil. Graphite is a very strong absorber of 1.06 micron light produced by the Nd:YAG laser. Portions of the contaminant are forced to infiltrate into spaces between the superficial epidermal cells, into hair ducts in the skin and into and/or adjacent to sebaceous glands.; The skin section is illuminated with short laser pulses at the matching wavelength, so as to impact sufficient energy to the contaminant to cause explosion in the contaminant. The energy released in the course of the explosions may blow off layers of dead skin cells and/or destroy tissue responsible for hair growth and/or sebum production.

Priority: US1998-0168202 Applic. Date: 1998-10- 06; US1994-0280928 Applic. Date: 1994-07-26; US1995-0489358 Applic. Date: 1995-06-12; US1994-0257021 Applic. Date: 1994-06-08; US1993-0005810 Applic. Date: 1993-01-19; US1991-0783789 Applic. Date: 1991- 10-29

Inventor: TANKOVICH NIKOLAI I (US); SVERDRUP JR LAWRENCE H (US); EPISCOPO RICHARD G (US)


Patent No.: US 6043204 A Issued: 2000-03-28

Title: Body cleansing composition providing protection against sunburn after rinsing

Application No.: US1998-0187085 Applic. Date: 1998-11- 05

Abstract: Disclosed in a body cleansing composition providing upon a single application protection against sunburn measured by Sun Protection Factor (SPF) of at least 15 as applied and SPF of at least 4, and preferably at least 5, after rinsing, consisting essentially of water; at icast onc first sunscreen compound which is a paramethoxycinnamate ester, and at least one second sunscreen compound able to absorb at least 50% of incident radiation at wave lengths from 290 to 320 nanometers; a combination of at least two surface active agents including a first anionic agent which can be an alkyl sulfate salt or an alkoxylated alkyl sulfate salt, and a second agent which can be nonionic, anionic or zwitterionic; at least one hydroxyethylated organic nitrogen compound fixative to enhance retention of SPF on the user's skin selected from the group consisting of N-(2-hydroxyethyl)lactamide and a polymeric quaternary ammonium salt having a plurality of quaternary ammonium groups and at least one 2- hydroxyethyl group; and at least one additive selected firom the group consisting of non-aggressive volatile organic liquids boiling within the range of 15 to 60+526 C, water-immiscible non-volatile organic carriers, and preservatives able to retard microbial spoilage, whereby protection against sunburn is imparted to a person in need thereof in a single application.

Priority: US1998 -0187085 Applic. Date: 1998-11-05; US1997-0064766P Applic. Date: 1997-11-07; US1998-0097234P Applic. Date: 1998-08-20

Inventor: KAUFMAN STACY R (US); DULAK MICHAEL (US)


Patent No.: US 6045575 A Issued: 2000-04- 04

Title: Therapeutic method and internally illuminated garment for the management of disorders treatable by phototherapy

Applicant: AMT INC (US)

Application No.: US1998-0015226 Applic. Date: 1998-01-29

Abstract: An apparatus for treating neonatal jaundice is in the form of a garment (10, 40) which has semiconductor light sources (14, 214, 314) affixed thereto for radiating toward the "inside" of the garment when the infant is dressed in the garment. A portable energy source such as batteries (318) or a fuel cell (360) powers the array of light sources. A method according to the invention vests the infant in the garment, and energizes the light sources by coupling a battery to the light sources, or fueling and starting the fuel cell. The therapy is continued for as long as desired or needed.

Priority: US1998-0015226 Applic. Date: 1998-01-29; US1997-0058469P Applic. Date: 1997-09-10

Inventor: ROSEN DANIELLE (US); ROSEN ARYE (US)


Patent No.: US 6048516 A Issued: 2000-04-11

Title: Light-screening agents

Applicant: ROCHE VITAMINS INC (US)

Application No.: US1998-0113863 Applic. Date: 1998-07-10

Abstract: The invention relates to a composition which comprises a dibenzoylmethane capable of absorbing UV-A radiation and a compound of formula I wherein R1 and R2 are independently hydrogen, alkyl or alkoxy containing 1 to 18 carbon atoms provided that R1 and R2 are not both hydrogen; and n is 1 or 2 in an amount effective to photostabilize the dibenzolymethane, and a cosmetically acceptable carrier, and to cosmetic light-screening compositions containing at least one of the above agents, the use of the cosmetic light-screening compositions for the protection of the human skin and human hair against the ultraviolet radiation of wavelengths between about 320 and 400 nm (UV-A) and optionally also between about 290 and 400 nm (UV-B).

Priority: EP1997-0111938 Applic. Date: 1997-07-14

Inventor: BRINGHEN ALAIN (CH); GONZENBACH HANS ULRICH (CH); POCHON MAGALI (CH)


Patent No.: US 6051211 A Issued: 2000-04-18

Title: Stable w/o photoprotective cosmetic emulsions

Applicant: OREAL (FR)

Application No.: US1998-0020042 Applic. Date: 1998-02-06

Abstract: Stable, water-resistant photoprotective water-in-oil cosmetic emulsions, well suited for the photoprotection of human skin and/or hair against the deleterious effects of UV irradiation, comprise an effective stabilizing/emulsifying amount of a pair of active emulsifying agents, said emulsifying agent pair comprising (i) at least one polyalkylpolyethersiloxane emulsifier substituted by polyoxyethylene and polyoxypropylene moieties grafted onto the backbone polymer thereof, and (ii) at least one water-in-oil emulsifying polyoxyalkylenated glycol fatty acid ester polymer.

Priority: FR1997-0001367 Applic. Date: 1997-02-06

Inventor: HANSENNE ISABELLE (FR); DE CHABANNES KARINE (FR)


Patent No.: US 6051243 A Issued: 2000-04- 18

Title: Polyaromatic amide compounds and pharmaceutical/cosmetic compositions comprised thereof

Applicant: CIRD (FR)

Application No.: US1997-0969762 Applic. Date: 1997-11-13

Abstract: Novel pharmaceutically/cosmetically-active polyaromatic amides have the structural formula (I): wherein Z is a radical -CO-NH- or -NH-CO-,and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

Priority: US1997-0969762 Applic. Date: 1997 -11-13; FR1993-0015066 Applic. Date: 1993-12-15; US1994-0356680 Applic. Date: 1994-12- 15

Inventor: BERNARDON JEAN-MICHEL (FR)


Patent No.: US 6060041 A Issued: 2000-05- 09

Title: Photoprotective cosmetic compositions containing a metal oxide nanopigment and an acrylic terpolymer, and use of these compositions for protecting keratinous material against ultraviolet radiation

Applicant: OREAL (FR)

Application No.: US1999-0332007 Applic. Date: 1999-06-14

Abstract: The present application relates to photoprotective cosmetic compositions containing at least one metal oxide nanopigment and an acrylic terpolymer, as well as to the use of these compositions to protect the skin, the hair, the eyelashes, the eyebrows or mucous membranes against ultraviolet radiation. The acrylic terpolymer comprises: a) about 20 to 70% by weight of a carboxylic acid containing alpha , beta -monoethylenic unsaturation, b) about 20 to 80% by weight of a non-surfactant monomer containing monoethylenic unsaturation, which is different from a), and c) about 0.5 to 60% by weight of a nonionic urethane monomer which is the product of reaction of a monohydric nonionic surfactant with a monoisocyanate containing monoethylenic unsaturation.; The metal oxide nanopigments are chosen in particular from coated or uncoated titanium, cerium, zirconium, iron and zinc oxide nanopigments, or mixtures thereof, and have an elementary particle size of greater than 5 nm and less than 100 nm.

Priority: FR1998-0007511 Applic. Date: 1998-06-15

Inventor: CANDAU DIDIER (FR); HANSENNE ISABELLE (US)


Patent No.: US 6060070 A Issued: 2000-05- 09

Title: Isoflavonoids for treatment and prevention of aging skin and wrinkles

Application No.: US1997-0873314 Applic. Date: 1997-06- 11

Abstract: A method of treating or preventing, in a person, one or more symptoms of aging skin, said method comprising topically administering to the skin of said person a composition comprising one or more isoflavonoids selected from the group consisting of genistein, daidzein, biochanin A, formononetin, O-desmethylangolensin, glycitin, and equol, in a topically acceptable base, wherein the isoflavonoid concentration is between 1 and 40 mg per gram of base.

Priority: US1997-0873314 Applic. Date: 1997-06-11

Inventor: GORBACH SHERWOOD L (US)


Patent No.: US 6060461 A Issued: 2000-05- 09

Title: Topically applied clotting material

Application No.: US1999- 0246231 Applic. Date: 1999-02-08

Abstract: A composition, system, articles and method for the enhancement of clotting in wounds with extravascular blood flow, especially where the surface of the tissue has been broken is described. The system consists of biotolerable, porous particulates applied to the surface of a wound with liquid blood thereon. The porous nature of the particulate material, either free-flowing or packaged or restrained on or in a surface, enhances clotting. Chemical or biochemical agents, such as additional clotting agents, therapeutic agents, antibiotics, clot strengthening agents (such as fibrous structural materials), and the like may optionally be included on, with or within the porous particles. The particles may comprise such diverse materials as organics, metallics, inorganics, ceramics, and the like, both natural and artificial.; It is generally preferred that the pore size distribution lies within a general range, and this range may vary from animal to animal and condition to condition, but generally falls within about 0.5 to 1000 nanometers or 3,000 to 200,000 Daltons.

Priority: US1999-0246231 Applic. Date: 1999-02-08; WO2000-US05220 Applic. Date: 2000-02-29

Inventor: DRAKE JAMES FRANKLIN (US)


Patent No.: US 6062590 A Issued: 2000 -05-16

Title: Air bag tear seam and method of manufacture

Applicant: TEXTRON AUTOMOTIVE CO INC (US)

Application No.: US1998-0051834 Applic. Date: 1998-09- 21

Abstract: An air bag cover (14) for use in a supplement inflatable restraint system includes an air bag cover skin made of a polymeric material. The cover skin includes a weakened tear seam region (16) for guiding the tearing of the air bag cover skin in response to air bag inflation. The tear seam region is weakened by photodegradation, i.e., selective exposure to ultraviolet light (20) which breaks polymer bonds within the polymeric material of the tear seam region. Photodegradation reduces the tensile strength and/or the percent elongation (measured at break) of the tear seam region (16) compared to the rest of the air bag cover skin (24).

Priority: US1998-0051834 Applic. Date: 1998-09-21; WO1996-US17947 Applic. Date: 1996-11-08; US1995-0006404P Applic. Date: 1995-11- 09

PCT Info:
PCT No. PCT/US96/17947
Sec 371 Date Sep. 21, 1998
Sec. 102(e) Date Sep. 21, 1998
PCT Filed Nov. 8, 1996
PCT Pub. No. WO97/17233
PCT Pub. Date May 15, 1997

Inventor: GALLAGHER MICHAEL J (US)


Patent No.: US 6063074 A Issued: 2000-05- 16

Title: Hair removal using a contaminant matched to a laser

Applicant: THERMOLASE CORP (US)

Application No.: US1996-0777576 Applic. Date: 1996-12- 31

Abstract: A device and process for the permanent removal of unwanted human hair. Hair on a section of skin is contaminated with a substance having high absorption of a frequency band of light. The skin is illuminated with light at this frequency band at sufficient intensity and duration to kill the follicles or the skin tissue feeding the hair. One embodiment to produce death of the follicles or the skin tissues feeding the hair is by photochemical reaction.

Priority: US1996- 0777576 Applic. Date: 1996-12-31; US1995-0468022 Applic. Date: 1995-06-06; US1993-0005810 Applic. Date: 1993-01-19; US1991-0783789 Applic. Date: 1991-10-29

Inventor: TANKOVICH NIKOLAI (US)


Patent No.: US 6066328 A Issued: 2000-05-23

Title: Cosmetic or dermatological composition comprising an oil -in-water emulsion comprising oily globules with a lamellar liquid crystal coating

Applicant: OREAL (FR)

Application No.: US1998-0185502 Applic. Date: 1998-11-04

Abstract: The present invention relates to a cosmetic or dermatological composition comprising an emulsion of oil-in-water type formed of oily globules which are each provided with a lamellar liquid crystal coating and are dispersed in an aqueous phase. Each oily globule containing at least one lipophilic compound which is cosmetically or dermatologically active is individually coated with a monolamellar or oligolamellar layer obtained from at least one lipophilic surface-active agent, from at least one hydrophilic surface-active agent and from at least one ionic amphiphilic lipid imparting to the emulsion a pH ranging from 5.5 to 7.5, the coated oily globules having a mean diameter of less than 500 nanometers.

Priority: US1998-0185502 Applic. Date: 1998-11-04; FR1994-0012005 Applic. Date: 1994-10-07; US1995-0540165 Applic. Date: 1995-10- 06

Inventor: RIBIER ALAIN (FR); SIMONNET JEAN-THIERRY (FR); MICHELET JACQUES (FR)


Patent No.: US 6066489 A Issued: 2000 -05-23

Title: Method for treating blood borne viral pathogens such as immunodeficiency virus

Applicant: ARROW INT INC (US)

Application No.: US1996-0708083 Applic. Date: 1996-08-30

Abstract: A method and apparatus for destroying blood borne pathogens is disclosed which utilizes a low intensity direct current to generate positive particles from various metals which destroy viral pathogens. A first electrode comprised of a metal such as silver is inserted into a patient's venous system. Then, a second electrode is placed on the patient's exterior in the vicinity of the first electrode. A low intensity direct current is applied to the first metal electrode which releases silver cations to be bonded to the virus, resulting in the denaturing of the virus. The first electrode is placed in the venous system of the infected patient via a catheter.

Priority: US1996-0708083 Applic. Date: 1996-08-30

Inventor: FIELDS CHARLES BRUCE (US); BURRIS PHILLIP F (US)


Patent No.: US 6068851 A Issued: 2000-05- 30

Title: Formulation for use in the prevention of pathogen induced diseases including HIV and HSV

Applicant: INFECTIO RECH INC (CA)

Application No.: US1999-0051300 Applic. Date: 1999-01-13

Abstract: This invention relates to formulations comprising film-forming components capable of forming per se a physical barrier to pathogens. Thermoreversible gels such as poloxamers are particularly preferred for that use. The film-forming formulations may further comprise microbicides, spermicides or any other drug, which choice is guided by the pathogen, organism or the disease to be inactivated or treated. The formulations are therefore efficient as a physical, and optionally, as a chemical or pharmacological barrier as well as usable as a sustained drug-release system at the locus of administration. A part of the drug may also be entrapped in liposomes or other drug carriers.; These formulations are intended for use in the prevention of sexually transmitted diseases, as well as in the treatment of infections, cancer, inflammation or any disease or state which requires a pharmacological treatment. Formulations are applicable to mucosae, skin and eye, for example.

Priority: WO1997-CA00319 Applic. Date: 1997-05-09; US1996- 0017106P Applic. Date: 1996-05-09

PCT Info:
PCT No. PCT/CA97/00319
Sec 371 Date Jan. 13, 1999
Sec. 102(e) Date Jan. 13, 1999
PCT Filed May 9, 1997
PCT Pub. No. WO97/42962
PCT Pub. Date Nov. 20, 1997

Inventor: BERGERON MICHEL G (CA); DESORMEAUX ANDRE (CA); TREMBLAY MICHEL (CA)


Patent No.: US 6071502 A Issued: 2000-06-06

Title: Photostable sunscreen compositions comprising dibenzoylmethane compounds and 2-hydroxybenzophenone-substituted silanes/organosiloxanes

Applicant: OREAL (FR)

Application No.: US1999- 0377739 Applic. Date: 1999-08-20

Abstract: Improvedly photostable, topically applicable cosmetic/dermatological sunscreen compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-irradiation, particularly solar radiation, comprise (1) a UV-photoprotecting effective amount of at least one dibenzoylmethane sunscreen compound and (2) a photostabilizing effective amount of at least one silane or organosiloxane bearing a 2- hydroxybenzophenone substituent.

Priority: FR1998-0010632 Applic. Date: 1998-08- 21

Inventor: FORESTIER SERGE (FR); RICHARD HERVE (FR)


Patent No.: US 6077294 A Issued: 2000-06- 20

Title: Method for non-invasive wrinkle removal and skin treatment

Applicant: CYNOSURE INC (US)

Application No.: US1998-0095789 Applic. Date: 1998-06-11

Abstract: A method for the treatment of wrinkles on human skin, by stimulating collagen growth beneath the epidermis layer, comprising the steps of: arranging a pulsed dye laser generator in light communication with a pulsed dye laser delivery device. The pulsed dye laser delivery device is applied against tissue having wrinkles. The pulsed dye laser generator generates a pulsed dye laser light. A pulsed dye laser light from the pulsed dye laser delivery device is directed onto the tissue, to reach hemoglobin in a collagen layer up to about 1.2 mm. beneath the surface of the tissue to effect growth changes therein.

Priority: US1998-0095789 Applic. Date: 1998-06-11

Inventor: CHO GEORGE (US); FURUMOTO HORACE W (US)


Patent No.: US 6080415 A Issued: 2000-06- 27

Title: Make-up product combining a photochromic pigment and a UV screening agent, and uses thereof

Applicant: OREAL (FR)

Application No.: US1999-0339097 Applic. Date: 1999-06-24

Abstract: A cosmetic make-up product, comprising first and second components, separately packaged, each containing a cosmetically acceptable medium, the first component containing at least one photochromic coloring agent which is capable of producing at least one color in the presence of ultraviolet light, and the second component containing at least one agent which screens ultraviolet light.

Priority: FR1998-0008085 Applic. Date: 1998-06- 25

Inventor: SIMON JEAN-CHRISTOPHE (FR)


Patent No.: US 6080425 A Issued: 2000-06- 27

Title: Boron compounds and complexes as skin-rejuvenating agents

Applicant: TOPGENE INC (US)

Application No.: US1998-0192814 Applic. Date: 1998-11-16

Abstract: Boron compounds/complexes, other than boric acid and boric acid salts, are utilized for rejuvenating of skin. The compounds/complexes have a central tetrahedral boron atom covalently bound to four ligands, which may be either identical or different from each other. Preferred ligands include an oxygen, nitrogen, carbon or sulfur atom, and more preferred ligands are saccharides or amino acids that form stable five- or six-membered rings with the boron atom. Especially preferred compounds have a dissociation constant of at least 3,000, and include a saccharide. Especially preferred complexes include a sodium, potassium, magnesium or calcium cation. The compounds/complexes are useful in rejuvenating skin, including decreasing skin wrinkles, improving skin thickness, increasing skin hydration, softness and elasticity, improving the skin color, and decreasing the number and size of age spots.; The compounds/complexes are preferably provided in a suitable solvent system, a microemuslion or macroemulsion form, or a suitable liposome, and may be applied in any suitable form, including creams, bath salts, cosmetics, and shampoos.

Priority: US1998- 0192814 Applic. Date: 1998-11-16; US1998-0086826P Applic. Date: 1998-05-26

Inventor: MILJKOVIC DUSAN (US); PIETRZKOWSKI ZBIGNIEW (US)


Patent No.: US 6080880 A Issued: 2000-06- 27

Title: Silicone-substituted cinnamamide/malonamide/malonate compounds and photoprotective compositions comprised thereof

Applicant: OREAL (FR)

Application No.: US1997-0980307 Applic. Date: 1997-11-28

Abstract: Novel silicone- substituted cinnamamide/malonamide/malonate compounds having the structural formulae (1) and (2): in which A is a radical of formula (3): are well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, and are also useful for photoprotecting such UV-sensitive substrates as plastics.

Priority: US1997- 0980307 Applic. Date: 1997-11-28

Inventor: RICHARD HERVE (FR); LEDUC MADELEINE (FR)


Patent No.: US 6083526 A Issued: 2000-07-04

Title: Use of isoflavonoids in the treatment or prevention of postpartum depression

Application No.: US1997-0861485 Applic. Date: 1997-05- 22

Abstract: A method of treating or preventing postpartum depression by administration of a composition containing one or more purified, naturally-occurring isoflavonoids.

Priority: US1997-0861485 Applic. Date: 1997-05-22

Inventor: GORBACH SHERWOOD L (US)


Patent No.: US 6093410 A Issued: 2000-07-25

Title: Personal care compositions

Applicant: PROCTER & GAMBLE (US)

Application No.: US1997- 0964325 Applic. Date: 1997-11-05

Abstract: Emulsion compositions, suitable for personal care applications such as hair styling, and other applications, are disclosed. The compositions comprise: a) a silicone functional polymer having the formula selected from the group consisting of: (AB)n; ABA; BAB; and mixtures thereof; wherein B is a silicone moiety comprising repeating units of: R is independently, C1-C30 alkyl, aryl, alkylaryl, haloalkyl, H, or C1-C6 alkoxy, wherein the weight average molecular weight of each silicone moiety B is independently from about 1500 to about 50,000; A is a polar polymeric moiety which is soluble or dispersible in mixtures of ethanol and water containing less than 60% ethanol by weight; and n is an integer of 1 or greater; wherein the molecular weight of the silicone functional polymer is at least about 2,000. b) an organopolysiloxane emulsion comprising:; (i) a polyorganosiloxane dispersed as particles in the emulsion, the polyorganosiloxane having an average particle size of less than about 150 nanometers, and (ii) a surfactant system for dispersing the organopolysiloxane in the emulsion; c) a carrier comprising at least about 0.5%, by weight of the composition, of a first solvent selected from the group consisting of water; water soluble organic solvents; organic solvents which are strongly to moderately strong in hydrogen-bonding parameter; and mixtures thereof; wherein the first solvent is other than C1-C3 monohydric alcohol, C1-C3 ketone and C1 -C3 ether; wherein the silicone functional polymer is present in an amount effective to stabilize the emulsion in the personal care composition.

Priority: US1997-0964325 Applic. Date: 1997-11 -05

Inventor: PEFFLY MARJORIE MOSSMAN (US); BOLICH JR RAYMOND EDWARD (US); TORGERSON PETER MARTE (US); MIDHA SANJEEV (US)


Patent No.: US 6096029 A Issued: 2000-08-01

Title: Laser method for subsurface cutaneous treatment

Applicant: LASER SKIN TONER INC (US)

Application No.: US1997-0804931 Applic. Date: 1997-02-24

Abstract: A laser method for selective photocoagulation of subsurface skin (dermis) for the purpose of increasing skin tone, reducing wrinkles, removing hair, removing tattoos or treating varicose veins without damaging the skin surface (epidermis). A diffuser lens in the laser apparatus is employed to focus the laser energy to the dermis. The laser apparatus includes a highly transmissive contact tip and cooling means to reduce heat build-up in the contact tip, as monitored by a thermocouple mechanism. The present invention can be used alone or in conjunction with superficial laser resurfacing or chemical peels to increase skin tone.

Priority: US1997-0804931 Applic. Date: 1997-02-24

Inventor: O'DONNELL JR FRANCIS E (US)


Patent No.: US 6096294 A Issued: 2000-08-01

Title: Photoprotective/cosmetic compositions comprising 2,4,6-tris[p-((2'-ethylhexyl)oxycarbonyl)anilino]-1,3,5-triazine and salicylate solvents therefor

Applicant: OREAL (FR)

Application No.: US1997-0775624 Applic. Date: 1997-01-02

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a photoprotecting effective amount of 2,4,6-tris[p-((2'-ethylhexyl)oxycarbonyl)anilino]-1,3,5-triazine and (ii) at least one homomenthyl and/or octyl salicylate solvent for the triazine sunscreen compound (i), in a cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: US1997-0775624 Applic. Date: 1997-01-02; FR1994-0006831 Applic. Date: 1994-06-03; US1995-0463508 Applic. Date: 1995-06- 05

Inventor: HANSENNE ISABELLE (FR); VAN LEEUWEN VICTORIA (FR)


Patent No.: US 6096697 A Issued: 2000-08- 01

Title: Personal cleansing compositions providing improved hair and skin conditioning

Applicant: PROCTER & GAMBLE (US)

Application No.: US1998- 0082877 Applic. Date: 1998-05-21

Abstract: The compositions of the present invention relate to improved personal cleansing compositions comprising a surfactant system, from above about 0.1% to below 1% of a nonionic or anionic water soluble polymer, a phase separation initiator and water. These compositions provide improved lathering and conditioning benefits.

Priority: US1998-0082877 Applic. Date: 1998-05-21; US1997-0786578 Applic. Date: 1997-01- 21

Inventor: WELLS ROBERT LEE (US)


Patent No.: US 6103221 A Issued: 2000-08- 15

Title: Photoprotective/cosmetic compositions comprising benzotriazole-substituted silicon compounds and benzoic triacid triesters

Applicant: OREAL (FR)

Application No.: US1999-0397514 Applic. Date: 1999-09-17

Abstract: Topically applicable cosmetic/dermatological sunscreen compositions well suited for the UV- photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a UV-photoprotecting effective amount of at least one solubilized organolipophilic silicon compound, whether silane or organopolysiloxane, bearing a benzotriazole function substituent and (ii) an amount of at least one benzoic triacid triester effective to (substantially) dissolve said at least one organolipophilic silicon compound.

Priority: FR1998-0011946 Applic. Date: 1998-09-24

Inventor: ARNAUD PASCAL (FR); VIARD MARTINE (FR)


Patent No.: US 6106514 A Issued: 2000-08-22

Title: Laser method for subsurface cutaneous treatment

Application No.: US1997-0943448 Applic. Date: 1997-10- 03

Abstract: A laser method for delivery of pulsed infrared laser energy to a predetermined depth below the surface of the epidermis is disclosed. The method can be used to increase skin tone and reduce wrinkles. For the purposes of increasing skin tone, a novel method for quantifying the effect in vivo is disclosed. Post-treatment topical application of a pharmaceutical mixture including anti-inflammatory, anti-oxidant and neocollagen promoting agents can be used to increase new collagen synthesis stimulated by the present invention.

Priority: US1997-0943448 Applic. Date: 1997-10-03; US1997-0804931 Applic. Date: 1997-02-24; US1996-0023252P Applic. Date: 1996-08- 12

Inventor: O'DONNELL JR FRANCIS E (US)


Patent No.: US 6114559 A Issued: 2000-09- 05

Title: Silicone-substituted cinnamamide/malonamide/malonate compounds and photoprotective compositions comprised thereof

Applicant: OREAL (FR)

Application No.: US1997-0969365 Applic. Date: 1997-11-28

Abstract: Novel silicone- substituted cinnamamide/malonamide/malonate compounds having the structural formulae (1) and (2): in which A is a radical of formula (3): are well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, and are also useful for photoprotecting such UV-sensitive substrates as plastics.

Priority: FR1996- 0014599 Applic. Date: 1996-11-28

Inventor: RICHARD HERVE (FR); LEDUC MADELEINE (FR)


Patent No.: US 6126612 A Issued: 2000-10-03

Title: Method for detecting cyanide in cutaneously transpired gas

Application No.: US1997-0970160 Applic. Date: 1997-11- 13

Abstract: A method of detecting cyanide concentration in the cutaneously transpired gas of a patient, allowing for the timely implementation of an appropriate treatment. Where the skin of a patient suffering from cyanide poisoning has been burnt, the present invention provides for a noninvasive means of cyanide treatment. In practice, a material is impregnated with methemoglobin and attached to a patient's skin. A barrier means located between the impregnated material and the patient's skin allows for the transfer of cyanide gas from the patient into the material. However, this barrier means does not allow for the transfer of the methemoglobin from the impregnated material into the patient's skin. The material is monitored for photometric change, and, where a change indicative of cyanide poinsoning is present, appropriate treatment is administered.

Priority: US1997- 0970160 Applic. Date: 1997-11-13; US1996-0749032 Applic. Date: 1996-11-14; US1995-0007397P Applic. Date: 1995-11-21; US1995-0007855P Applic. Date: 1995-12-01

Inventor: ROIZEN MICHAEL F (US); MOSS JONATHAN (US); PECK CARL (US)


Patent No.: US 6126948 A Issued: 2000-10- 03

Title: Stable oil-in-water emulsion, process for its manufacture and its use in the cosmetic and dermatological fields

Applicant: OREAL (FR)

Application No.: US1998-0041664 Applic. Date: 1998-03-13

Abstract: A fine and stable emulsion of an oily phase in an aqueous phase containing ionic polymer particles, the oil globules of the emulsion having a mean size of at most 500 nm, a process for the stabilization of fluid emulsions, a process for the preparation of these emulsions and their use in the cosmetic and dermatological fields and more particularly as composition for anti-sun protection.

Priority: FR1997-0003017 Applic. Date: 1997-03-13

Inventor: SIMONNET JEAN-THIERRY (FR); LE VERGE DANIELLE (FR); LEGRET SYLVIE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 6127415 A Issued: 2000-10-03

Title: Apoptosis inducing adamantyl derivatives and their usage as anti-cancer agents

Applicant: GALDERMA RES & DEV (FR)

Application No.: US1999-0214422 Applic. Date: 1999-04-14

Abstract: The present invention relates to specific adamantyl or adamantyl group derivative containing retinoid compounds induce apoptosis of cancer cells. These adamantyl retinoid derivatives are useful for the treatment of many cancers and solid tumors, especially androgen-independent prostate cancer, skin cancer, pancreatic carcinomas, colon cancer, melanoma, ovarian cancer, liver cancer, small cell lung carcinoma, non-small cell lung carcinoma, cervical carcinoma, brain cancer, bladder cancer, breast cancer, neuroblastoma/glioblastoma, and leukemia.; Also, the invention relates to novel adamantyl or adamantyl group derivative compounds which are useful as active agents for the treatment or prevention of keratinization disorders and other dermatological conditions, and other diseases.

Priority: US1999-0214422 Applic. Date: 1999-04-14; US1996-0021285P Applic. Date: 1996-07-08; WO1997-US11564 Applic. Date: 1997-07-08

PCT Info:
PCT No. PCT/US97/11564
Sec 371 Date Apr. 14, 1999
Sec. 102(e) Date Apr. 14, 1999
PCT Filed Jul. 8, 1997
PCT Pub. No. WO98/01132
PCT Pub. Date Jan. 15, 1998

Inventor: PFAHL MAGNUS (US); LU XIAN-PING (US); RIDEOUT DARRYL (US); ZHANG HONGYUE (US)


Patent No.: US 6132740 A Issued: 2000-10- 17

Title: Resorcinol derivatives

Applicant: PFIZER (US)

Application No.: US1998-0153479 Applic. Date: 1998-09-15

Abstract: The present invention relates to the use of certain resorcinol derivatives as skin lightening agents.

Priority: US1998-0153479 Applic. Date: 1998-09-15; US1997-0059625P Applic. Date: 1997-09-23

Inventor: HU LAN (US)


Patent No.: US 6132750 A Issued: 2000-10- 17

Title: Particles of cross-linked proteins and polysaccharides with hydroxamic groups for chelating metals and their uses notably in cosmetics

Applicant: COLETICA (FR)

Application No.: US1998-0108670 Applic. Date: 1998-07-01

Abstract: The invention relates to small sized particles. These particles comprise at least on the surface thereof a wall composed of a mixture of at least one protein and at least one polysaccharide which are cross- linked, preferably by interfacial cross-linking with a polyfunctional acylating agent which forms at least amide and ester bonds, and optionally anhydride bonds with amine, hydroxyl or carboxyl functions of the protein and of the polysaccharide, and which comprise hydroxamic groups on the surface thereof for chelating metal ions. These particles can be used in cosmetics or in pharmacy notably for the chelation or release of metal ions.

Priority: FR1998-0004611 Applic. Date: 1998-04- 14

Inventor: PERRIER ERIC (FR); BUFFEVANT CHANTAL (FR); BONNET ISABELLE (FR); LEVY MARIE-CHRISTINE (FR)


Patent No.: US 6139049 A Issued: 2000-10-31

Title: Air bag tear seam and method of manufacture

Applicant: TEXTRON AUTOMOTIVE CO INC (US)

Application No.: US2000-0482133 Applic. Date: 2000-01-12

Abstract: A method for manufacture an air bag cover includes providing a cover skin made of a polymeric material and weakening a seam region in the skin by selective exposure to ultraviolet light.

Priority: US2000-0482133 Applic. Date: 2000-01-12; US1995-0006404P Applic. Date: 1995-11-09

Inventor: GALLAGHER MICHAEL J (US)


Patent No.: US 6139718 A Issued: 2000-10-31

Title: Electrode with improved signal to noise ratio

Applicant: CYGNUS THERAPEUTIC SYSTEMS (US)

Application No.: US1997- 0824143 Applic. Date: 1997-03-25

Abstract: An electrode assembly for sensing an electrochemical signal diffused from a source to a working electrode which is comprised of a plurality of substantially separated working electrode surfaces is disclosed. The electrode of the invention is comprised of 1) a working electrode made up of a plurality of working electrode surfaces or components and 2) a electrically insulating gap defined by adjacent edges of 1) insulating the working electrode surfaces or components from each other. The working electrode components are configured to receive electrochemical signal from two or preferably three dimensions simultaneously. The working electrode components configured over the same surface as a single electrode provide (1) an improved signal to noise ratio as compared to a single electrode by reducing noise, and (2) provide an overall enhanced signal after sensing for a given period of time.

Priority: US1997-0824143 Applic. Date: 1997-03-25

Inventor: KURNIK RONALD T (US); TAMADA JANET (US); TIERNEY MICHAEL J (US)


Patent No.: US 6143282 A Issued: 2000-11-07

Title: Photoprotective/cosmetic compositions comprising benzotriazole-substituted silicon sunscreens and cinnamic/salicylic acid solubilizing agents therefor

Applicant: OREAL (FR)

Application No.: US1999-0397513 Applic. Date: 1999-09-17

Abstract: Topically applicable cosmetic/dermatological sunscreen compositions well suited for the UV-photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a UV-photoprotecting effective amount of at least one solubilized organolipophilic silicon compound, whether solid silane or organopolysiloxane, bearing a benzotriazole function substituent and (ii) an amount of at least one cinnamic acid sunscreen compound and/or at least one salicylic acid sunscreen compound effective to (substantially) dissolve said at least one organolipophilic silicon compound.

Priority: FR1998-0012042 Applic. Date: 1998-09-25

Inventor: HANSENNE ISABELLE (US); JOSSO MARTIN (FR); DE CHABANNES KARINE (FR)


Patent No.: US 6146649 A Issued: 2000-11-14

Title: Photobluing/whitening- resistant cosmetic/dermatological compositions comprising TiO2 pigments and deformable hollow particulates

Applicant: OREAL (FR)

Application No.: US1998-0134739 Applic. Date: 1998-08-14

Abstract: Topically applicable cosmetic/sunscreen/dermatological compositions, well suited for improved photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation and/or for the therapeutic treatment of a disease state of the skin or mucosae, essentially in the absence of photobluing/whitening, comprise at least one titanium dioxide (nano)pigment and an effective photobluing/whitening-reducing amount of deformable hollow particulates (microspheres) having a particle size ranging from 1 mu m to 250 mu m and which comprise an expanded copolymer of vinylidene chloride, acrylonitrile and a (meth)acrylate.

Priority: US1998-0134739 Applic. Date: 1998-08-14; FR1995-0008564 Applic. Date: 1995-07-13; FR1995-0008565 Applic. Date: 1995-07-13; US1996-0679806 Applic. Date: 1996-07-15

Inventor: HANSENNE ISABELLE (FR)


Patent No.: US 6147102 A Issued: 2000-11- 14

Title: Clonidine preparations

Applicant: CURATEK PHARMACEUTICALS HOLDIN (US)

Application No.: US1999-0427367 Applic. Date: 1999-10- 26

Abstract: Sympathetically maintained peripheral neuropathic pain syndromes are relieved by topically applying, to the affected region of a patient suffering from such pain, a pain relieving amount of an aqueous gel comprising clonidine, a water-gelling amount of a pharmaceutically acceptable gelling agent and having a physiologically tolerable pH value. Pain relief was achieved with applied amounts of clonidine in the range of about 2 milligrams per day to about 6 mg per day.

Priority: US1999-0427367 Applic. Date: 1999-10-26

Inventor: BORGMAN ROBERT J (US)


Patent No.: US 6150413 A Issued: 2000-11-21

Title: Triaromatic compounds and pharmaceutical/cosmetic compositions comprised thereof

Applicant: GALDERMA RECH DERMATOLOGIQUE (FR)

Application No.: US1998-0084235 Applic. Date: 1998-05-26

Abstract: Novel pharmaceutically/cosmetically-active triaromatic compounds have the structural formula (I): and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular, bone and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

Priority: FR1997-0006340 Applic. Date: 1997-05-23

Inventor: BERNARDON JEAN-MICHEL (FR); NEDONCELLE PHILIPPE (FR)


Patent No.: US 6150459 A Issued: 2000-11-21

Title: Comb polymers for regulating cell surface interactions

Applicant: MASSACHUSETTS INST TECHNOLOGY (US)

Application No.: US1999-0290140 Applic. Date: 1999-04-13

Abstract: Synthetic comb copolymers which elicit controlled cellular response, methods of applying these polymers to various surfaces, and methods of using the polymers for modifying biomaterial surfaces, in tissue engineering applications and as drug delivery devices are provided. The comb copolymers are comprised of hydrophobic polymer backbones and hydrophilic, non-cell binding side chains which can be end-capped with cell-signaling ligands that guide cellular response. By mixing non-cell binding combs with ligand-bearing combs, the surface concentration and spatial distribution of one or more types of ligands, including adhesion peptides and growth factors, can be tuned on a surface to achieve desired cellular response. In one embodiment, the combs are used as stabilizing agents for dispersion polymerization of latexes.; The comb-stabilized latexes can be applied to substrates by standard coating operations to create a bioregulating surface, or used as drug delivery agents. In another embodiment, the combs can be blended in small quantities to a hydrophobic matrix polymer and processed to affect the surface segregation of the comb. The comb copolymers are formed in one embodiment by providing a biodegradable polyester backbone that includes reactive groups, and reacting the reactive groups in the backbone with reactive chain ends on a low molecular weight hydrophilic polymer. In another embodiment, non-biodegradable comb copolymers are formed by free radical synthesis of a hydrophobic monomer and a hydrophilic macromonomer.; In all of the above embodiments, a portion of the hydrophilic polymer side chains can be covalently coupled to cell- signaling ligands such as adhesion peptides or growth factors to control cellular response.

Priority: US1999-0290140 Applic. Date: 1999-04-13; US1998-0081596P Applic. Date: 1998-04-13

Inventor: MAYES ANNE M (US); GRIFFITH LINDA G (US); IRVINE DARRELL J (US); BANERJEE PALLAB (US); JOHNSON TERRY D (US)


Patent No.: US 6156750 A Issued: 2000-12- 05

Title: Bioactive bicyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof

Applicant: GALDERMA RECH DERMATOLOGIQUE (FR)

Application No.: US1999-0229829 Applic. Date: 1999-01-13

Abstract: Novel pharmaceutically/cosmetically-active bicyclic aromatic compounds have the structural formula (I): and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

Priority: US1999- 0229829 Applic. Date: 1999-01-13; FR1995-0000659 Applic. Date: 1995-01-20; US1998-0005601 Applic. Date: 1998-01-09; US1996-0589388 Applic. Date: 1996-01-22

Inventor: BERNARDON JEAN-MICHEL (FR)


Patent No.: US 6156788 A Issued: 2000-12-05

Title: Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof

Applicant: GALDERMA RECH DERMATOLOGIQUE (FR)

Application No.: US1999-0369875 Applic. Date: 1999-08-09

Abstract: Novel pharmaceutically/cosmetically-active polycyclic aromatic compounds have the structural formula (I): wherein Ar is a radical having one of the formulae (a)-(e): and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

Priority: US1999-0369875 Applic. Date: 1999-08-09; FR1994-0005019 Applic. Date: 1994-04-26; US1997-0971983 Applic. Date: 1997-11-17; US1995-0429096 Applic. Date: 1995-04-26

Inventor: BERNARDON JEAN-MICHEL (FR)


Patent No.: US 6159456 A Issued: 2000-12- 12

Title: Photoprotective/cosmetic compositions comprising camphorsulfonic acid and bisresorcinyltriazine sunscreens

Applicant: OREAL (FR)

Application No.: US2000-0503940 Applic. Date: 2000-02-14

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for the synergistically enhanced photoprotection of human skin and/or hair against the damaging effects of UV-irradiation, particularly solar radiation, comprise synergistically UV-photoprotecting effective amounts of each of (i) benzene-1,4-di(3-methylidene-10- camphorsulfonic acid, or partially or completely neutralized form thereof, and (ii) at least one bisresorcinyltriazine compound, formulated into a topically applicable, cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: US2000-0503940 Applic. Date: 2000-02-14; FR1999- 0001730 Applic. Date: 1999-02-12

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6159914 A Issued: 2000-12- 12

Title: Detergent cosmetic compositions and use thereof

Applicant: OREAL (FR)

Application No.: US1998-0055666 Applic. Date: 1998-04- 07

Abstract: Novel detergent compositions comprising, in a cosmetically acceptable medium, (A) a washing base comprising at least one ether sulphate anionic surfactant and at least one surfactant of alkylbetaine type, and (B) a conditioning system comprising at least one cationic polymer, preferably dimethyldiallylammonium, and at least one aminosilicone, and uses thereof.

Priority: FR1997-0004219 Applic. Date: 1997-04-07

Inventor: DECOSTER SANDRINE (FR); BEAUQUEY BERNARD (FR)


Patent No.: US 6162211 A Issued: 2000-12-19

Title: Skin enhancement using laser light

Applicant: THERMOLASE CORP (US)

Application No.: US1997-0985856 Applic. Date: 1997-12-04

Abstract: Methods of applying laser light to the skin, and apparatus therefor, include methods for removing hair, for bleaching hair, for transdermal drug delivery, for sensing a body function, for skin tightening, and for imaging subsurface structures are described. The hair removal methods and the hair bleaching methods include infiltrating a transparent fluid with an index of refraction greater than that of skin tissue into hair ducts to help transmit the laser light down the hair ducts. The transdermal drug delivery and body function sensing methods include exfoliating layers of the stratum corneum from a section of skin with laser light. A transdermal drug delivery patch can be placed over the exfoliated skin section, or an electrical sensor can be placed over the exfoliated skin section.; The skin tightening method includes implanting a light absorbing material in the dermis of a section of skin and illuminating the skin section to disturb the dermis in such a way as to cause a healing reaction that forms more collagen fibers. The imaging system includes a confocal microscope that has been adapted to view only a time-gated portion of laser light reflected from the skin.

Priority: US1997-0985856 Applic. Date: 1997-12-04; US1997-0052718P Applic. Date: 1997-07-16; US1996-0033238P Applic. Date: 1996-12-05

Inventor: TANKOVICH NIKOLAI I (US); DASSE KURT A (US); FAIRCHILD PAUL W (US); ZHAO ZHONG-QUAN (US); KOLINKO VLADIMIR G (US)


Patent No.: US 6165440 A Issued: 2000 -12-26

Title: Radiation and nanoparticles for enhancement of drug delivery in solid tumors

Applicant: UNIV TEXAS (US)

Application No.: US1998-0112491 Applic. Date: 1998-07-09

Abstract: The present invention discloses a method/system utilizing interaction of electromagnetic pulses or ultrasonic radiation with nano- and microparticles for enhancement of drug delivery in solid tumors. The particles can be attached to antibodies directed against antigens in tumor vasculature and selectively delivered to tumor blood vessel walls. Cavitation induced by ultrasonic waves or local heating of the particles by pulsed electromagnetic radiation results in perforation of tumor blood vessels, microconvection in the interstitium, and perforation of cancer cell membrane, and therefore, provides enhanced delivery of macromolecular therapeutic agents from blood into cancer cells with minimal thermal and mechanical damage to normal tissues.

Priority: US1998-0112491 Applic. Date: 1998-07-09; US1997-0052202P Applic. Date: 1997-07-09

Inventor: ESENALIEV RINAT O (US)


Patent No.: US 6171579 B1 Issued: 2001-01- 09

Title: Synergistically UV-photoprotecting triazine/silicone compositions

Applicant: OREAL (US)

Application No.: US1999-0258852 Applic. Date: 1999-02-26

Abstract: The invention relates to novel cosmetic and/or dermatological compositions, in particular for photoprotecting the skin and/or the hair, characterized in that they comprise, in a cosmetically acceptable support in particular of oil-in-water type, (i) as first screening agent, at least one specific 1,3,5-triazine derivative, and (ii) as second screening agent, a silicon derivative containing a benzotriazole function, the said first and second screening agents being present in the said compositions in an amount which is effective for producing synergistic activity with respect to the sun protection factors imparted.Application to protecting the skin and the hair against the effects of ultraviolet radiation.

Priority: FR1998-0002416 Applic. Date: 1998-02-27

Inventor: ALLARD DELPHINE (FR); GOMBERT CHRIST GRAVE OVER E LE (FR)


Patent No.: US 6171603 B1 Issued: 2001-01-09

Title: Bioaromatic amido compounds and pharmaceutical/cosmetic compositions comprised thereof

Applicant: GALDERMA RECH DERMATOLOGIQUE (US)

Application No.: US1999-0246715 Applic. Date: 1999-02-09

Abstract: Novel pharmaceutically/cosmetically-active biaromatic amido compounds have the structural formula (I):in which Ar is a radical selected from among those of the following formulae (a)-(e):and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

Priority: US1999-0246715 Applic. Date: 1999 -02-09; FR1995-0002133 Applic. Date: 1995-02-23; US1996-0605960 Applic. Date: 1996-02- 23

Inventor: BERNARDON JEAN-MICHEL (FR); VIGNE LAURENCE (FR)


Patent No.: US 6174518 B1 Issued: 2001-01- 16

Title: Photoprotective/cosmetic compositions comprising w/o/w stable triple emulsions

Applicant: OREAL (US)

Application No.: US1999-0297718 Applic. Date: 1999-07-27

Abstract: The present invention relates to a cosmetic or dermatological emulsion of the water/oil/water (W/O/W) type, characterized in that it comprises:(a) an external aqueous phase and(b) a non-continuous fatty phase constituting, with an internal aqueous phase, a water/oil (W/O) primary emulsion, the said fatty phase comprising, as lipophilic emulsifier, at least one block copolymer composed of a polymer block derived from a monohydroxycarboxylic acid and of a polymer block derived from an alkylglycol or from a polyalkylene glycol;(c) at least one photoprotective system capable of screening out UV (UV-A and/or UV-B) radiation.The invention also relates to its uses in and for the manufacture of cosmetic or dermatological compositions for the photoprotection of the skin or hair.

Priority: FR1997-0011494 Applic. Date: 1997-09-16; WO1998-FR01876 Applic. Date: 1998-09-01

Inventor: ALLARD DELPHINE (FR)


Patent No.: US 6183728 B1 Issued: 2001-02- 06

Title: Screening cosmetic composition comprising one nanopigment of metallic oxide and one fat-soluble screening polymer

Applicant: OREAL (US)

Application No.: US1999-0307805 Applic. Date: 1999-05-10

Abstract: The present invention is directed to a composition for screening out ultraviolet radiation, comprising, in association, at least one nanopigment of metallic oxide and at least one UV-screening fat-soluble polymer.

Priority: US1999-0307805 Applic. Date: 1999-05-10; FR1991-0010731 Applic. Date: 1991-08-29; US1997-0896428 Applic. Date: 1997-07-17

Inventor: FORESTIER SERGE (FR); HANSENNE ISABELLE (FR)


Patent No.: US 6187001 B1 Issued: 2001-02-13

Title: Apparatus and method for removing hair

Applicant: RADIANCY INC (US)

Application No.: US1998-0220580 Applic. Date: 1998-12- 28

Abstract: An apparatus and method for removing hairs from a region of skin, the apparatus including:a housing having an opening therein, the housing forming a cavity enclosing a volume of air when the opening is placed in contact with the region of skin;a switchable heat source disposed within the housing that rapidly heats the volume of air to a temperature sufficient to destroy the hair by conduction of heat along the length of the hair to a follicle thereof; anda power source that controllably energizes the heat source.

Priority: IL1997-0122840 Applic. Date: 1997-12-31; WO1998-IL00605 Applic. Date: 1998-12-14

Inventor: AZAR ZION (IL); SHALEV PINCHAS (IL)


Patent No.: US 6194902 B1 Issued: 2001-02-27

Title: Pipe testing apparatus and method using electrical or electromagnetic pulses transmitted into the pipe

Application No.: US1997-0807645 Applic. Date: 1997-02-27

Abstract: A method and system for detecting corrosion on a pipe or a pipeline. An electrical or electromagnetic pulse is transmitted into a pipe or pipeline to travel as a propagating electromagnetic wave along the pipeline to a receiving location. Both the distance traveled from the transmitting and receiving location, and also the time interval for such travel are measured. Velocity of the wave is detected as a means of ascertaining whether corrosion is present. Various embodiments, using both multi-channel and single cables, are used to transmit the detected waves, and the waves are received at a plurality of spaced locations along the length of the pipe or pipeline.; For an insulated pipeline, the signals can be received by a directional antenna, and the pulses can be transmitted into the pipeline by means of either an antenna placed directly adjacent to the pipeline or a magnet electrical contact member in direct contact with the pipeline.

Priority: US1997-0807645 Applic. Date: 1997-02-27; US1996-0012336P Applic. Date: 1996-02-27

Inventor: KUO JOHN T (US); BURNETT GALE D (US)


Patent No.: US 6197020 B1 Issued: 2001-03- 06

Title: Laser apparatus for subsurface cutaneous treatment

Applicant: SUBLASE INC (US)

Application No.: US1998-0177472 Applic. Date: 1998-10- 23

Abstract: A laser apparatus for selective photocoagulation of subsurface skin (dermis) for the purpose of increasing skin tone, reducing wrinkles, removing hair, removing tattoos or treating varicose veins without damaging the skin surface (epidermis). A diffuser lens in the laser apparatus is employed to focus the laser energy to the dermis. The laser apparatus includes a highly transmissive contact tip and cooling means to reduce heat build-up in the contact tip, as monitored by a thermocouple mechanism. The device can be used alone or in conjunction with superficial laser resurfacing or chemical peels to increase skin tone.

Priority: US1998-0177472 Applic. Date: 1998-10-23; US1997- 0804931 Applic. Date: 1997-02-24; US1996-0023252P Applic. Date: 1996-08-12

Inventor: O'DONNELL JR FRANCIS E (US)


Patent No.: US 6197757 B1 Issued: 2001-03-06

Title: Particles, especially microparticles or nanoparticles, of crosslinked monosaccharides and oligosaccharides, processes for their preparation and cosmetic, pharmaceutical or food compositions in which they are present

Applicant: COLETICA (FR)

Application No.: US1999-0350131 Applic. Date: 1999-07- 09

Abstract: Particles comprising an outer wall formed of one or more saccharide components selected from the group consisting of monosaccharides and oligosaccharides crosslinked by interfacial crosslinking in emulsion, preferably at room temperature, with a polyfunctional acylating crosslinking agent to produce ester linkages between the acylatable hydroxyl group(s) of the primary alcohol(s) of the saccharide component and the acyl groups of the polyfunctional acylating agent. These particles can be used for the manufacture of cosmetic, pharmaceutical and food compositions.

Priority: FR1998-0008809 Applic. Date: 1998-07-09

Inventor: PERRIER ERIC (FR); REY-GOUTENOIRE SYLVIE (FR); BUFFEVANT CHANTAL (FR); LEVY MARIE-CHRISTINE (FR); PARIOT NADINE (FR); EDWARDS FLORENCE (FR); ANDRY MARIE-CHRISTINE (FR)


Patent No.: US 6200552 B1 Issued: 2001-03- 13

Title: Photostabilized sunscreen compositions comprising dibenzoylmethane compounds

Applicant: OREAL (US)

Application No.: US1999-0350910 Applic. Date: 1999-07-12

Abstract: Improvedly photostable, topically applicable cosmetic/dermatological sunscreen compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a photoprotecting effective amount of at least one dibenzoylmethane UV-screening compound, and (ii) an amount of at least one silane or organosiloxane substituted by a benzylidenecamphor functional group effective to photostabilize said at least one dibenzoylmethane UV-screening compound (i).

Priority: FR1998-0008937 Applic. Date: 1998-07-10

Inventor: RICHARD HERVE (FR); FORESTIER SERGE (FR)


Patent No.: US 6203802 B1 Issued: 2001-03-20

Title: Composition for the cosmetic and/or pharmaceutical treatment of the upper layers of the epidermis by topical application to the skin, and corresponding preparation process

Applicant: OREAL (US)

Application No.: US1994-0195081 Applic. Date: 1994-02-14

Abstract: Composition comprising biodegradable nanoparticles encapsulating oils which are active and/or which contain an active ingredient having a cosmetic and/or pharmaceutical action in the upper layers of the epidermis. The nanoparticles are preferably prepared from a polymer of (C2-C12) alkyl cyanoacrylate.

Priority: US1994-0195081 Applic. Date: 1994-02-14; FR1990-0003418 Applic. Date: 1990-03-16; US1992-0961537 Applic. Date: 1992-10-15; US1991-0668308 Applic. Date: 1991-03- 13

Inventor: HANDJANI ROSE-MARIE (FR); RIBIER ALAIN (FR)


Patent No.: US 6207175 B1 Issued: 2001-03- 27

Title: Powdered cosmetic and/or dermatological lotion and its use

Applicant: OREAL (US)

Application No.: US1999-0428986 Applic. Date: 1999-10-29

Abstract: A cosmetic and/or dermatological lotion comprising an aqueous phase and a powdered phase, the powdered phase comprising at least one active powder and hollow particles based on at least one acrylic or methacrylic polymer or copolymer, the aqueous phase being present in an amount ranging from 90 to 99.99% by weight with respect to the total weight of the lotion. The inventive lotion has the advantage of being soft on application and of exhibiting a powdered phase which does not become clogged. The lotion may be used for caring for, cleaning, removing make-up from and/or coloring the skin, mucous membranes and/or scalp.

Priority: FR1998-0013867 Applic. Date: 1998-11-04

Inventor: LEBRETON FRANCOISE (FR)


Patent No.: US 6208749 B1 Issued: 2001-03- 27

Title: Systems and methods for the multispectral imaging and characterization of skin tissue

Applicant: ELECTRO OPTICAL SCIENCES INC (US)

Application No.: US1998 -0032450 Applic. Date: 1998-02-27

Abstract: Systems and methods for the multispectral imaging of skin tissue enables automatic characterization of the condition of a region of interest of the skin, based on direct digital imaging of the region of interest or the digitization of color photographic slides of the region of interest, illuminated by appropriately filtered light. Preferably, a digital image at a low spectral band is automatically segmented and that segmented mask is used to segment the other images by a digital processor. Parameters related to the texture, asymmetry, blotchiness and border irregularities are also automatically estimated. The region of interest is automatically characterized by the digital processor, based on those parameters. The region of interest may include a skin lesion, in which case the present invention enables the characterization of the lesion as malignant or benign.

Priority: US1998-0032450 Applic. Date: 1998-02-27; US1997 -0039218P Applic. Date: 1997-02-28; US1997-0039407P Applic. Date: 1997-02-28

Inventor: GUTKOWICZ-KRUSIN DINA (US); ELBAUM MAREK (US); GREENEBAUM MICHAEL (US); JACOBS ADAM (US)


Patent No.: US 6214034 B1 Issued: 2001-04-10

Title: Method of selective photothermolysis

Applicant: RADIANCY INC (US)

Application No.: US1998-0076098 Applic. Date: 1998-05- 12

Abstract: A method and apparatus for selective photothermolysis of a target tissue within surrounding tissue. The target and the surrounding tissue are heated to a predetermined temperature of about 60 DEG C. by a pulsed heat source such as a flash lamp which creates a temperature gradient in the air included in a cavity formed between the housing of the apparatus and the surrounding tissue. The surface temperature of the tissue is monitored by a sensor unit. When the tissue surface reaches the predetermined temperature the target tissue is heated to the point of coagulation, preferably by narrow band electromagnetic radiation. The temperature difference between the coagulating target and the surrounding tissue is sufficiently mild that heat diffusing out of the target does not damage the surrounding tissue, even in the case of a relatively large target such as varicose veins.; The heating action may be terminated by automatically pumping air or another suitable coolant into the cavity when the surface of the tissue reaches a preset value or by lifting the apparatus off the tissue. The apparatus may include a programmable controller which may be programmed locally or remotely with the treatment parameters.

Priority: US1998-0076098 Applic. Date: 1998-05-12; US1996-0707562 Applic. Date: 1996-09-04

Inventor: AZAR ZION (IL)


Patent No.: US 6214323 B1 Issued: 2001-04- 10

Title: Photoprotective/cosmetic compositions comprising camphorsulfonic acid, bisresorcinyltriazine and benzoazolyl/benzodiazolyl sunscreens

Applicant: OREAL (US)

Application No.: US2000-0503169 Applic. Date: 2000-02-14

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for the synergistically enhanced photoprotection of human skin and/or hair against the damaging effects of UV-irradiation, particularly solar radiation, comprise synergistically UV-photoprotecting effective amounts of each of (a) benzene- 1,4-bis(3-methylidene-10-camphorsulfonic acid), optionally in neutralized form thereof, (b) at least one bisresorcinyltriazine compound, and (c) at least one compound containing at least two benzoazolyl groups or at least one benzodiazolyl group, formulated into a topically applicable, cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: FR1999-0001733 Applic. Date: 1999-02- 12

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6214324 B1 Issued: 2001-04- 10

Title: Photoprotective/cosmetic compositions comprising benzotriazole and benzoazolyl/benzodiazolyl sunscreens

Applicant: OREAL (US)

Application No.: US2000-0503941 Applic. Date: 2000-02-14

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for the synergistically enhanced photoprotection of human skin and/or hair against the damaging effects of UV-irradiation, particularly solar radiation, comprise synergistically UV-photoprotecting effective amounts of each of (a) at least one benzotriazole compound, and (b) at least one compound containing at least two benzoazolyl groups and/or at least one benzodiazolyl group, formulated into a topically applicable, cosmetically acceptable vehicle, diluent or carrier therefore.

Priority: FR1999-0001728 Applic. Date: 1999-02- 12

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6221343 B1 Issued: 2001-04- 24

Title: Benzimidazole/benzofuryl-benzazole silicon compounds and UV-photoprotective compositions comprised thereof

Applicant: OREAL (US)

Application No.: US2000-0503943 Applic. Date: 2000-02-14

Abstract: Novel liposoluble and photostable N-substituted benzimidazole/benzofuryl-benzazole silicon-containing compounds are conspicuously excellent UV-absorbers and are conveniently formulated, e.g., into topically applicable sunscreen/cosmetic compositions well suited for the UV-photoprotection of human skin and/or hair.

Priority: FR1999-0001734 Applic. Date: 1999-02-12

Inventor: RICHARD HERVE (FR); LUPPI BERNADETTE (FR)


Patent No.: US 6225328 B1 Issued: 2001-05-01

Title: Adamantyl-substituted retinoids and pharmaceutical/cosmetic compositions comprised thereof

Applicant: GALDERMA RECH DERMATOLOGIQUE (US)

Application No.: US1999-0296656 Applic. Date: 1999-04- 23

Abstract: Pharmaceutically/cosmetically-active adamantyl-substituted retinoid compounds have the structural formula (I):wherein Ar is a radical having one of the formulae (a)-(d):and are useful for the treatment of disorders and/or ailments manifesting an overregulation of PAR receptors and/or a hypervitaminosis A.

Priority: US1999-0296656 Applic. Date: 1999-04-23; FR1995- 0005279 Applic. Date: 1995-05-03; US1996-0642424 Applic. Date: 1996-05-03

Inventor: BERNARDON JEAN-MICHEL (FR)


Patent No.: US 6228344 B1 Issued: 2001-05-08

Title: Method of measuring physiological function

Applicant: MALLINCKRODT INC (US)

Application No.: US1999-0258148 Applic. Date: 1999-02-26

Abstract: A method of measuring physiological function of a group of body cells, includes the step of selecting a detectable agent capable of emitting a measurable electromagnetic emission. The agent is introduced into body fluid wich contacts the group of body cells. The emission is measured, and physiological function is determined based on measurement of the emission.

Priority: US1999-0258148 Applic. Date: 1999-02-26; US1997-0816332 Applic. Date: 1997-03-13

Inventor: DORSHOW RICHARD B (US); ACHILEFU SAMUEL (US); RAJAGOPALAN RAGHAVAN (US); BUGAJ JOSEPH E (US)


Patent No.: US 6228350 B1 Issued: 2001-05-08

Title: Method of depigmenting and/or bleaching skin and/or body hair or head hair

Applicant: OREAL (US)

Application No.: US2000-0489840 Applic. Date: 2000-01-24

Abstract: The use, in a topical cosmetic composition, or for the manufacture of a topical dermatological composition, intended for depigmenting and/or bleaching human skin, body hair or head hair, of at least one compound comprising a phenyloxime fragment.

Priority: FR1999-0000882 Applic. Date: 1999-01- 27

Inventor: TULOUP REMY (FR); PHILIPPE MICHEL (FR)


Patent No.: US 6231839 B1 Issued: 2001-05- 15

Title: Stable cosmetic composition comprising a poly (2-acrylamido-2- methylpropanesulphonic acid) polymer uncoated solid particles and an oily dispersing polymer

Applicant: OREAL (US)

Application No.: US1999-0467244 Applic. Date: 1999-12-20

Abstract: The invention relates to a composition, in particular for cosmetic, dermatological, hygiene and/or pharmaceutical use, comprising at least one crosslinked poly(2 -acrylamido-2-methylpropanesulphonic acid) polymer neutralized to at least 90%, uncoated solid particles and an oily dispersing polymer. It also relates to the cosmetic applications of such a composition.

Priority: FR1998-0016049 Applic. Date: 1998-12-18

Inventor: TERREN NADIA (FR); FAVRE SOPHIE (FR)


Patent No.: US 6235016 B1 Issued: 2001-05-22

Title: Method of reducing sebum production by application of pulsed light

Application No.: US1999-0270327 Applic. Date: 1999-03-16

Abstract: A method of reducing sebum production in human skin, used primarily for cosmetic purposes, including the prevention of acne vulgaris, comprising the use of pulsed light having a wavelength, if monochromatic, or a wavelength range, if produced by a filtered non- monochromatic source, which targets the lipids contained within the sebaceous gland, thus destroying the differentiated and mature sebocytes by photothermolysis without damage to the surrounding and overlying tissue or to the basement membrane of the sebaceous gland.

Priority: US1999-0270327 Applic. Date: 1999-03-16

Inventor: STEWART BOB W (US)


Patent No.: US 6248311 B1 Issued: 2001-06- 19

Title: Photoprotective/cosmetic compositions comprising bisresorcinyltriazine and benzoazolyl/benzodiazolyl

Applicant: OREAL (US)

Application No.: US2000- 0503944 Applic. Date: 2000-02-14

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for the synergistically enhanced photoprotection of human skin and/or hair against the damaging effects of UV-irradiation, particularly solar radiation, comprise synergistically UV-photoprotecting effective amounts of each of (a) at least one bisresorcinyltriazine compound, and (b) at least one compound containing two benzoazolyl groups, or at least one benzodiazolyl group, formulated into a topically applicable, cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: FR1999-0001732 Applic. Date: 1999-02-12

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6251373 B1 Issued: 2001-06-26

Title: Photoprotective/cosmetic compositions comprising benzotriazole, bisresorcinyltriazine and benzoazolyl/benzodiazolyl sunscreens

Applicant: OREAL (US)

Application No.: US2000-0503942 Applic. Date: 2000-02- 14

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for the synergistically enhanced photoprotection of human skin and/or hair against the damaging effects of UV- irradiation, particularly solar ratiation, comprise synergistically UV-photoprotecting effective amounts of each of (a) at least one benzotriazole compound, (b) at least one bisresorcinyltriazine compound and (c) at least one compound containing at least two benzoazolyl groups per molecule and/or at least one compound containing, per molecule, at least one benzodiazolyl group, formulated into a topically applicable, cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: FR1999-0001731 Applic. Date: 1999-02-12

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6251412 B1 Issued: 2001-06- 26

Title: Cosmetic composition comprising pigments and an antiperspirant and use of such a composition

Applicant: OREAL (US)

Application No.: US1999-0356336 Applic. Date: 1999-07-19

Abstract: A composition, in particular a cosmetic composition, which can especially be in the form of an emulsion, a gel or a vesicle dispersion, the said composition comprising a pulverulent phase in an amount of less than or equal to 80% by weight relative to the total weight of the composition, this composition comprising at least one pigment and at least one antiperspirant. Use of such a composition in cosmetics, in particular for make-up, in order to improve the staying power of the color of the composition.

Priority: FR1998-0009155 Applic. Date: 1998-07-17

Inventor: BAZIN ROLAND (FR); BARA ISABELLE (FR)


Patent No.: US 6261542 B1 Issued: 2001-07- 17

Title: Composition for protecting the skin or the hair, containing nanopigments and a solid elastomeric polyorganosiloxane combined with a fatty phase

Applicant: OREAL (US)

Application No.: US1999-0467002 Applic. Date: 1999-12-20

Abstract: A composition for topical application containing nanopigments and a solid elastomeric polyorganosiloxane combined with a fatty phase, in order to improve the protection factor provided by the nanopigments and stabilize the composition.

Priority: US1999-0467002 Applic. Date: 1999-12-20; FR1996- 0009525 Applic. Date: 1996-07-29; US1997-0905782 Applic. Date: 1997-07-29

Inventor: BARA ISABELLE (FR); LEMANN PATRICIA (FR)


Patent No.: US 6267755 B1 Issued: 2001-07-31

Title: Method of hair depilation

Applicant: M & E CORP OF DELAWARE (US)

Application No.: US1999-0335698 Applic. Date: 1999-06-18

Abstract: A method of hair depilation using an Nd:YAG laser which causes local heating at the hair bulb due to the absorption of the oxyhemoglobin contained in the capillaries. The Nd:YAG laser operates at 1060 nanometers. Each pulse is a special pulse having a first portion and a second portion, where power output in the first portion is 20 times greater than power output in the second portion. That way, the first portion of each pulse is used to quickly heat up the tissue to a damaging temperature, and the second portion maintains that temperature to cause hair removal for the tissue.

Priority: US1999-0335698 Applic. Date: 1999-06-18; US1999-0133844P Applic. Date: 1999-05-12; US1998-0103534P Applic. Date: 1998-10- 08

Inventor: CLEMENTI GABRIELE (IT); BERNABEI GIAN FRANCO (IT); GALLI MAURO (IT)


Patent No.: US 6267771 B1 Issued: 2001-07-31

Title: Hair removal device and method

Applicant: THERMOTREX CORP (US)

Application No.: US1996-0607525 Applic. Date: 1996-02- 27

Abstract: A device and process for the permanent removal of unwanted human hair. Hair on a section of skin is contaminated with a substance having high absorption of a frequency band of light. The skin is illuminated with light at this frequency band at sufficient intensity and duration to kill the follicles or the skin tissue feeding of the hair. Specific embodiments to produce death of the follicles or the skin tissues feeding the hair by heating and by photochemical reaction.

Priority: US1996-0607525 Applic. Date: 1996-02-27; US1993-0091247 Applic. Date: 1993-07-12; US1991-0783789 Applic. Date: 1991-10-29; US1993-0005810 Applic. Date: 1993-01- 19

Inventor: TANKOVICH NIKOLAI I (US); HUNTER ALLEN M (US); TANG KENNETH Y (US)


Patent No.: US 6274150 B1 Issued: 2001-08-14

Title: Nanoemulsion based on phosphoric acid fatty acid esters and its uses in the cosmetics, dermatological, pharmaceutical, and/or ophthalmological fields

Applicant: OREAL (US)

Application No.: US1999-0468325 Applic. Date: 1999-12- 21

Abstract: The present invention provides a nanoemulsion, that includes:an oily phase dispersed in an aqueous phase; andat least one anionic surfactant selected from the group including phosphoric acid fatty esters and oxyethylenated derivatives thereof, and mixtures thereof; whereinthe oily phase includes oil globules having a number-average size of less than 100 nm;wherein the oily phase includes at least one oil having a molecular weight of greater than 400; and wherein a weight ratio of the oily phase to the surfactant ranges from 2 to 10. The invention also provides a process for making the nanoemulsion, and methods for its use. The nanoemulsion is ideally transparent and stable on storage. It can ideally contain large amounts of oil while retaining good transparency and good cosmetic properties.; The nanoemulsion is particularly useful in compositions, including topical, pharmaceutical, dermatological, cosmetic, opthalmic, and opthalmologic. The composition is also particularly useful in applications to the skin, hair, scalp, mucous membranes, and eyes.

Priority: FR1998- 0016370 Applic. Date: 1998-12-23

Inventor: SIMONNET JEAN-THIERRY (FR); SONNEVILLE ODILE (FR); LEGRET SYLVIE (FR)


Patent No.: US 6277111 B1 Issued: 2001-08-21

Title: Depilation

Applicant: ICN PHOTONICS LTD (US)

Application No.: US1999-0345144 Applic. Date: 1999-06- 30

Abstract: Mammalian hair is depilated using a laser source capable of emitting pulse radiation, each pulse having a duration of 1 microsecond to 1 millisecond, and having a wavelength in the range of 600 to 1500 nanometers. The radiation exposure dose is preferably between 2 and 25 J/cm2. A selected area of a subject's skin is irradiated by the pulsed radiation, the area having a plurality of irradiation zones. The laser source is successively pulsed so as to irradiate successive zones of the treatment area with the radiation, so as to destroy subdermal biological material associated with hair growth.

Priority: WO1994-GB02682 Applic. Date: 1994-12-07; US1997-0972416 Applic. Date: 1997-11-18; US1999-0345144 Applic. Date: 1999-06-30; GB1993-0025109 Applic. Date: 1993-12- 08

Inventor: CLEMENT ROBERT MARC (GB); KIERNAN MICHAEL N (GB)


Patent No.: US 6280715 B1 Issued: 2001-08- 28

Title: Cosmetic composition useful notably for the skin whitening and melanogenesis inhibiting agent containing such a cosmetic composition

Applicant: EXSYMOL SA (US); BABIZHAYEV MARK A (US)

Application No.: US1998-0126322 Applic. Date: 1998-07- 31

Abstract: Cosmetic composition useful notably in the whitening of skin which it includes, in association with any suitable excipient, at least one compound of the following general formula (I):wherein:R1 represents a hydrogen atom, a linear or branched alkyl group or a thiazoline group,R2 represents a hydrogen atom, a linear or branched alkyl group or a linear or branched alkyl group substituted by a carboxyl, a hydroxyl, an amine or a thiol group,R3 represents a hydrogen atom, a linear or branched alkyl group, an arylalkyl group, an acyl group or an acyloxy group,R4 represents a hydrogen atom or a linear or branched alkyl group,R5 represents a hydrogen atom, a hydroxyl group or a linear or branched alkyl group.

Priority: MC1997-0002383 Applic. Date: 1997-07- 31

Inventor: SEGUIN MARIE-CHRISTINE (MC); BABIZHAYEV MARK A (RU)


Patent No.: US 6283986 B1 Issued: 2001-09- 04

Title: Method of treating wounds with ultraviolet C radiation

Applicant: MEDFAXX INC (US)

Application No.: US2000-0515155 Applic. Date: 2000-02- 29

Abstract: A method of treating wounds includes the step of applying UVC radiation to the wound for a time and at a proximity and intensity sufficient to have a bacteriocidal effect. The method is particularly effective when carried out with a UVC lamp having an intensity of between 5 and 20 muW/cm2, with a duration of between about 5 seconds and 1 minute and a proximity to the wound of between about 1/4 and 3 inches from the wound being preferred. It has been observed that such application of UVC radiation can kill up to 100 percent of the microorganisms present in a wound, thereby enabling the wound to heal free of infection.

Priority: US2000-0515155 Applic. Date: 2000-02-29; US1999-0122263P Applic. Date: 1999-03-01

Inventor: JOHNSON ROBERT G (US)


Patent No.: US 6284126 B1 Issued: 2001-09-04

Title: Electrode with improved signal to noise ratio

Applicant: CYGNUS THERAPEUTIC SYSTEMS (US)

Application No.: US2000- 0650025 Applic. Date: 2000-08-28

Abstract: An electrode assembly for sensing an electrochemical signal diffused from a source to a working electrode which is comprised of a plurality of substantially separated working electrode surfaces is disclosed. The electrode of the invention is comprised of 1) a working electrode made up of a plurality of working electrode surfaces or components and 2) a electrically insulating gap defined by adjacent edges of 1) insulating the working electrode surfaces or components from each other. The working electrode components are configured to receive electrochemical signal from two or preferably three dimensions simultaneously. The working electrode components configured over the same surface as a single electrode provide (1) an improved signal to noise ratio as compared to a single electrode by reducing noise, and (2) provide an overall enhanced signal after sensing for a given period of time.

Priority: US2000-0650025 Applic. Date: 2000-08-28; US1997-0824143 Applic. Date: 1997-03-25

Inventor: KURNIK RONALD T (US); TAMADA JANET (US); TIERNEY MICHAEL (US)


Patent No.: US 6287543 B1 Issued: 2001-09- 11

Title: Composition especially in the form of emulsion, gel or aqueous solution, including a crosslinked poly (2-acrylamido-2-methylpropanesulphonic acid) polymer neutralized to at least 90%

Applicant: OREAL (US)

Application No.: US1997-0885798 Applic. Date: 1997-06-30

Abstract: The invention relates to a cosmetic, dermatological, hygienic or pharmaceutical composition which is in the form of, or includes, an aqueous gel or an aqueous, hydroalcoholic or multiphase solution additionally including at least one crosslinked poly(2- acrylamido-2-methylpropanesulphonic acid) polymer neutralized to at least 90% and pigments or water- soluble dyes.

Priority: FR1996-0008112 Applic. Date: 1996-06-28

Inventor: TERREN NADIA (FR); FAVRE SOPHIE (FR)


Patent No.: US 6296835 B1 Issued: 2001-10-02

Title: Photoprotective/cosmetic compositions comprising bis-hydroxyphenylbenzotriazole and benzazolyl/benzodiazolyl sunscreens

Applicant: OREAL (US)

Application No.: US2000-0589116 Applic. Date: 2000-06-08

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for the SPF synergistically enhanced photoprotection of human skin and/or hair against the damaging effects of UV-irradiation, particularly solar radiation, comprise synergistically UV- photoprotecting effective amounts of each of (a) at least one bis-hydroxyphenylbenzotriazole sunscreen compound and (b) at least one second sunscreen compound which comprises at least two benzazolyl functional groups per molecule and/or at least one sunscreen compound which comprises at least one benzodiazolyl functional group per molecule, formulated into a topically applicable, cosmetically acceptable vehicle, diluent or carrier therefor, advantageously formulated as an oil-in-water emulsion.

Priority: FR1999-0007205 Applic. Date: 1999-06-08

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6306130 B1 Issued: 2001-10-23

Title: Apparatus and methods for removing blood vessels

Applicant: GEN HOSPITAL CORP (US)

Application No.: US1999-0287872 Applic. Date: 1999-04-07

Abstract: Methods and apparatus for inducing necrosis and degradation of blood vessels are described. The invention is suitable to treat various conditions such as varicose veins and telangiectasia. The apparatus for inducing degradation of a blood vessel in a tissue, e.g., skin, includes an external energy source that non-invasively delivers to the blood vessel energy that is preferentially absorbed by the blood vessel to heat the blood vessel walls to a temperature of at least about 60 degrees centigrade, and a pressure source connected to the energy source to collapse the blood vessel once the blood vessel walls have been heated to at least about 60 degrees centigrade for a period of time and with a force sufficient to permanently weld the apposed walls of the blood vessel together, whereby the blood vessel undergoes necrosis and degradation.

Priority: US1999-0287872 Applic. Date: 1999-04-07; US1998-0081062P Applic. Date: 1998-04-07

Inventor: ANDERSON RICHARD ROX (US); DIERICKX CHRISTINE C (BE)


Patent No.: US 6312673 B2 Issued: 2001-11-06
Publication No.: US20010026789A1 Published: 2001-10-04

Title: Photostabilized sunscreen compositions comprising dibenzoylmethane compounds and benzylidenecamphor- substituted silanes/organosiloxanes

Applicant: OREAL (US)

Application No.: US2001-0761827 Applic. Date: 2001-01-18

Abstract: Improvedly photostable, topically applicable cosmetic/dermatological sunscreen compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a photoprotecting effective amount of at least one dibenzoylmethane UV-screening compound, and (ii) an amount of at least one silane or organosiloxane substituted by a benzylidenecamphor functional group effective to photostabilize said at least one dibenzoylmethane UV- screening compound (i).

Priority: US2001-0761827 Applic. Date: 2001-01-18; FR1998-0008937 Applic. Date: 1998-07-10; US1999-0350910 Applic. Date: 1999-07-12

Inventor: RICHARD HERVE (FR); FORESTIER SERGE (FR)


Patent No.: US 6316030 B1 Issued: 2001-11-13

Title: Use of nanoscale sterols and sterol esters

Applicant: COGNIS DEUTSCHLAND GMBH (US)

Application No.: US1999- 0418667 Applic. Date: 1999-10-14

Abstract: A composition containing an effective amount of nanoparticles selected from the group consisting of nanoscale sterols, nanoscale sterol esters, and mixtures thereof.

Priority: US1999-0418667 Applic. Date: 1999-10-14; US1998- 0104144P Applic. Date: 1998-10-14

Inventor: KROPF CHRISTIAN (DE); FOERSTER THOMAS (DE); FABRY BERND (DE); HOLLENBROCK MARTINA (DE)


Patent No.: US 6325769 B1 Issued: 2001-12- 04

Title: Method and apparatus for therapeutic treatment of skin

Applicant: COLLAPEUTICS LLC (US)

Application No.: US1999-0340997 Applic. Date: 1999-06- 28

Abstract: A method and apparatus of reducing skin wrinkles, including applying an acoustic pulse or train of pulses to a subsurface region of human skin without damaging or adversely affecting the surface or epidermis layer of the skin. The pulses cause changes in the dermis layer of the skin that result in enhanced smoothness of the epidermis layer of the skin. In particular, the acoustic pulses are applied to the dermis layer at an amplitude and for a period of time sufficient to induce production of new connective tissue that reduces or eliminate of skin wrinkles.

Priority: US1999-0340997 Applic. Date: 1999-06-28; US1998-0998963 Applic. Date: 1998-12-29

Inventor: KLOPOTEK PETER J (US)


Patent No.: US 6333026 B1 Issued: 2001-12- 25

Title: Use of an indigoid compound in a cosmetic composition, in particular a make-up composition, in order to confer on it antimicrobial properties and the property of lengthy hold over time

Applicant: OREAL (US)

Application No.: US1999-0458207 Applic. Date: 1999-12-10

Abstract: The invention relates to the use of at least one compound of formula:in which R1 and R'1 are C1-C18 alkyl radicals which are optionally substituted by one or more halogens or hydroxyls and/or are interrupted by one or more heteroatoms, and R2 to R5 and R'2 to R'5 are hydrogen or halogen atoms, hydroxyl radicals or C1-C6 alkyl, alkyloxy, acyl or acyloxy radicals, in a cosmetic composition, in particular a make-up composition, in order to confer on it antimicrobial properties and properties of lengthy hold over time and/or of non-migration and/or of freedom from transfer and/or of non-formation of streaks.The invention also relates to a cosmetic composition, in particular a make-up composition and especially an eyeshadow, comprising such a compound in a silicone binder.

Priority: FR1998-0015693 Applic. Date: 1998-12-11

Inventor: LEMANN PATRICIA (FR)


Patent No.: US 6335022 B1 Issued: 2002-01-01

Title: Nanoemulsion based on oxyethylenated or non- oxyethylenated sorbitan fatty esters, and its uses in the cosmetics, dermatological and/or ophthalmological fields

Applicant: OREAL (US)

Application No.: US1999- 0459580 Applic. Date: 1999-12-13

Abstract: The present invention relates to a nanoemulsion, the oil globules of which have an average size of less than 100 nm, comprising (1) a surfactant which is solid at a temperature of less than or equal to 45 DEG C., which surfactant is chosen from sorbitan fatty esters and oxyethylenated sorbitan fatty esters, (2) at least one oil having a molecular weight of greater than 400 and (3) at least one ionic amphiphilic lipid chosen from the group formed by the alkaline salts of dicetyl and dimyristyl phosphate, the alkaline salts of cholesterol sulphate, the alkaline salts of cholesterol phosphate, lipoamino acids, the sodium salts of phosphatidic acid, cationic amphiphilic lipids and alkylsulfonic derivatives, the ratio by weight of the amount of oily phase to the amount of surfactant ranging from 2 to 10.; The surfactant used is, for example, chosen from sorbitan monostearate, sorbitan monopalmitate and sorbitan 20 EO tristearate. The emulsion obtained is transparent and stable on storage. It can comprise large amounts of oil while retaining good transparency and while having good cosmetic properties. The invention also relates to the use of the nanoemulsion according to the invention in the cosmetics and dermatological fields, in particular for moisturizing the skin and/or mucous membranes, as well as for treating the hair, and in the ophthalmological field, as an eye lotion for treating the eyes.

Priority: FR1998- 0015949 Applic. Date: 1998-12-17

Inventor: SIMONNET JEAN-THIERRY (FR); SONNEVILLE ODILE (FR); LEGRET SYLVIE (FR)


Patent No.: US 6342486 B1 Issued: 2002-01-29

Title: Polymer glucan ether derivatives, their manufacturing as well as their use

Applicant: MIBELLE AG COSMETICS (CH)

Application No.: US1997-0896926 Applic. Date: 1997-07-18

Abstract: A method for treatment of skin includes topical application of a composition containing a therapeutically effective amount of a 1,3-beta-glucan ether derivative. Such application effectively provides treatment and/or prophylaxis of various skin-related problems, such as neurodermatitis and psoriasis, and reduces the evidence of aging by minimizing wrinkles. In an advantageous embodiment, the glucan ether derivative is present in the composition in a range of concentration of about 0.002% to about 8% by weight. In another embodiment the glucan ether derivative is advantageously carboxymethyl glucan sodium salt.

Priority: DE1996-1029117 Applic. Date: 1996-07-19

Inventor: ZUELLI FRED (CH); SUTER FRANZ (CH)


Patent No.: US 6344186 B1 Issued: 2002-02-05

Title: Oil-in-water emulsions containing a 1,3,5-triazine derivative and a copolyol silicone and cosmetic applications

Applicant: OREAL (FR)

Application No.: US1999-0355739 Applic. Date: 1999-12-22

Abstract: The present application relates to novel oil-in -water emulsions comprising i) at least one specific 1,3,5-triazine derivative and ii) at least one polyalkyl-polyethersiloxane carrying polyoxyalkylene groups grafted onto the main silicone chain; with the proviso that the said emulsions do not comprise cetylstearyltrimethylammonium chloride.Another subject-matter of the present invention is the use of such emulsions in the manufacture of cosmetic or dermatological compositions intended for the photoprotection of the skin and/or hair and/or other keratinous substances against ultraviolet radiation, in particular solar radiation.

Priority: FR1997-0015310 Applic. Date: 1997-12-04; WO1998-FR02425 Applic. Date: 1998-11-13

Inventor: HANSENNE ISABELLE (FR); JOSSO MARTIN (FR); NODARI LAURENT (FR)


Patent No.: US 6344206 B1 Issued: 2002-02-05

Title: Combination of a retinoid with a polyamine polymer

Applicant: OREAL (FR)

Application No.: US2000-0652012 Applic. Date: 2000-08-31

Abstract: A composition comprising the combination of at least one retinoid selected from the group consisting of vitamin A (retinol) and the bioconvertible precursors of vitamin A and at least one polyamine polymer.

Priority: US2000-0652012 Applic. Date: 2000 -08-31; FR1997-0006533 Applic. Date: 1997-05-28; US1998-0085839 Applic. Date: 1998-05- 28

Inventor: NGUYEN QUANG LAN (FR); BOUSSOUIRA BOUDIAF (FR); PRINCE STEPHANIE (FR); GIACOMONI PAOLO (FR)


Patent No.: US 6358514 B1 Issued: 2002-03-19

Title: Combination of a retinoid with a histidine derivative

Applicant: OREAL (FR)

Application No.: US1999-0317859 Applic. Date: 1999-05-25

Abstract: A composition containing at least one retinoid and at least one histidine derivative. The histidine derivative improves the stability of the retinoid in the composition. The composition may be used to treat skin and/or hair.

Priority: FR1998- 0006603 Applic. Date: 1998-05-26

Inventor: BOUSSOUIRA BOUDIAF (FR); PHILIPPE MICHEL (FR)


Patent No.: US 6366802 B1 Issued: 2002-04-02

Title: Photon irradiation human pain treatment monitored by thermal imaging

Applicant: BALES SCIENT INC (US)

Application No.: US2000- 0482465 Applic. Date: 2000-01-13

Abstract: Photo illumination of sites along a nerve supplying a painful region is conducted one at a time until a thermal image of that region or one related to it shows a significant change in temperature, at which time the treatment is terminated. If it is an extremity (hand or foot) that is has pain symptoms, one extremity is treated by exposing its nerve sites to photo illumination while the other extremity is observed by a thermograph instrument. Use of the thermal image as a feedback technique allows the treatment to be terminated as soon as the favorable temperature change takes place.

Priority: US2000-0482465 Applic. Date: 2000-01- 13; US1999-0229689 Applic. Date: 1999-01-13

Inventor: HABER CONSTANCE (US); BALES MAURICE (US)


Patent No.: US 6368577 B1 Issued: 2002-04-09

Title: Nanoscale organic UV filters

Applicant: COGNIS DEUTSCHLAND GMBH (DE)

Application No.: US1999-0456369 Applic. Date: 1999-12 -08

Abstract: A cosmetic or pharmaceutical composition used for blocking the penetration of ultraviolet radiation, the composition containing nanoscale organic UV filters having a mean diameter of from 10 to 300 nm.

Priority: US1999-0456369 Applic. Date: 1999-12-08; US1998-0111834P Applic. Date: 1998-12-11

Inventor: KROPF CHRISTIAN (DE); DOLHAINE HANS (DE); FOERSTER THOMAS (DE); FABRY BERND (DE)


Patent No.: US 6369510 B1 Issued: 2002-04-09

Title: Blue tinted automobile lamp capsule

Applicant: OSRAM SYLVANIA INC (US)

Application No.: US2000-0482706 Applic. Date: 2000-01-13

Abstract: The invention involves application of a luster coating to the exterior of a glass lamp capsule envelope to obtain a blue coloration of the transmitted light. The result is a higher color temperature light source that is commercially preferred. The preferred blue luster is formed from a coating solution containing organometallic components and solvent, that is heat treated in an oxidizing atmosphere to form a gold containing bismuth-titanium oxide material. The filament is adjusted to yield the overall necessary number of lumens. The blue luster tinted automobile lamp capsule is a durable, and yields the proper number of lumens with little or no increase in glare. The blue luster tinted lamp capsule is therefore compliant with legal standards.

Priority: US2000-0482706 Applic. Date: 2000-01-13

Inventor: SHAW CATHY M (US); CALLAHAN SUSAN L (US); YOUNG PAUL A (US)


Patent No.: US 6372200 B2 Issued: 2002-04-16
Publication No.: US20010031247A1 Published: 2001-10-18

Title: UV-photoprotecting sunscreen compositions comprising immixture of polyethylene/carboxylated polyethylene polymers

Applicant: OREAL (FR)

Application No.: US2001-0771661 Applic. Date: 2001-01-30

Abstract: Topically applying cosmetic/dermatological compositions well suited for both effective and SPF-enhanced UV-photoprotection of human skin and/or hair contain (a) an effective UV-photoprotecting amount of at least one UV-A and/or UV-B sunscreen and (b) an amount of immixture of ethylene polymers effective to enhance the SPF value of said at least one UV-A and/or UV-B sunscreen (a), said immixture of ethylene polymers (b) comprising (i) at least one carboxylated polyethylene and (ii) at least one polyethylene, formulated into a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor, advantageously formulated as an oil-in-water emulsion.

Priority: FR2000-0001535 Applic. Date: 2000-02- 08

Inventor: JOSSO MARTIN (FR); MEURISSE STEPHANIE (FR)


Patent No.: US 6372717 B1 Issued: 2002-04- 16

Title: Synthetic peptides and their use in cosmetic or dermopharmaceutical compositions

Applicant: SEDERMA S A (FR)

Application No.: US1999-0242687 Applic. Date: 1999-02-23

Abstract: The invention concerns the use of peptides of general formula R1-L-Tyr-L-Arg-R2 in which R1=H or a R3-C=0 with R3=a C1 to C20 alkyl chain, linear or branched, saturated or unsaturate, hydroxylated or not, or with R3=an aryl, aryl-alkyl or alkyloxy or aryloxy or arylalkyloxy group, and in which R2=OH or a O-R4 group with R4=a C1 to C20 alkyl chain, or R2=a NH2, NHX or NXX group with X=a C1 to C4 alkyl chain. The peptides have a soothing effect on the skin, including by topical application, and attenuates the effects of benign skin sores (after shave irritation, sunstroke, frostbite, chaps, depilation). They are used in acceptable cosmetic excipients and in effective in vivo concentrations.

Priority: WO1996-FR01322 Applic. Date: 1996-08- 23

Inventor: GREFF DANIEL (FR)


Patent No.: US 6375936 B1 Issued: 2002-04- 23

Title: Photoprotective cosmetic composition containing an anionic surfactant, compounds for screening out ultraviolet radiation and a cationic or zwitterionic amphiphilic compound, and use thereof

Applicant: OREAL (FR)

Application No.: US2000-0486240 Applic. Date: 2000-02-24

Abstract: The invention relates to a cosmetic composition, in particular for photoprotecting the skin and/or the hair, in the form of a dispersion comprising two immiscible phases stabilized with at least one anionic surfactant chosen from the salts of fatty acids and of monovalent or polyvalent metals, of ammonium or of organic bases, a compound for screening out ultraviolet radiation, which can be adsorbed at the interface of the said immiscible phases, derived from benzylidenecamphor and comprising at least one partially or totally neutralized sulphonic acid function, a metal oxide nanopigment coated with hydrophobic hydrocarbon-based coating agents and a cationic or zwitterionic amphiphilic compound which leads, with the anionic surfactant, to the formation of a compound capable of lowering the water/liquid paraffin interface tension at 40 DEG C.; by more than 14 mN.m-1 for an anionic surfactant concentration of 0.1 mmol/100 g, by more than 26 mN.m-1 for an anionic surfactant concentration of 0.5 mmol/100 g and by more than 33 mN.m-1 for an anionic surfactant concentration of 1 mmol/100 g.

Priority: FR1998-0008828 Applic. Date: 1998-07-09; WO1999 -FR01608 Applic. Date: 1999-07-05

Inventor: ALLARD DELPHINE (FR); CANDAU DIDIER (FR); NICOLAS-MORGANTINI LUC (FR)


Patent No.: US 6375960 B1 Issued: 2002-04-23

Title: Nanoemulsion based on ethoxylated fatty ethers or on ethoxylated fatty esters and its uses in the cosmetics, dermatological and/or ophthalmological fields

Applicant: OREAL (FR)

Application No.: US1999- 0474074 Applic. Date: 1999-12-29

Abstract: The present invention provides a nanoemulsion, that includes:an oily phase dispersed in an aqueous phase; andat least one surfactant that is solid at a temperature of less than or equal to 45 DEG C. and which is selected from the group including ethoxylated fatty ethers and ethoxylated fatty esters, and mixtures thereof; whereinthe oily phase includes oil globules having a number-average size of less than 100 nm;wherein the oily phase includes at least one oil having a molecular weight of greater than 400; andwherein a weight ratio of the oily phase to the surfactant ranges from 2 to 10. The invention also provides a process for making the nanoemulsion, and methods for its use. The emulsion is ideally transparent and stable on storage. It can ideally contain large amounts of oil while retaining good transparency and good cosmetic properties.; The nanoemulsion is particularly useful in compositions, including topical, pharmaceutical, cosmetic, opthalmic, ophthalmologic. The composition is also particularly useful in applications to the skin, hair, scalp, mucous membranes, and eyes.

Priority: FR1998-0016570 Applic. Date: 1998-12-29

Inventor: SIMONNET JEAN-THIERRY (FR); SONNEVILLE ODILE (FR); LEGRET SYLVIE (FR)


Patent No.: US 6376679 B2 Issued: 2002-04-23
Publication No.: US20010053856A1 Published: 2001-12- 20

Title: Photoprotective/cosmetic compositions comprising novel benz-x-azole-substituted silane/siloxane sunscreens

Applicant: OREAL (FR)

Application No.: US2000- 0740063 Applic. Date: 2000-12-20

Abstract: Photoprotective, topically applicable sunscreen/cosmetic compositions well suited for the UV-photoprotection of human skin and/or hair, comprise an effective UV-photoprotecting amount of at least one novel benz-x-azole-substituted silane or siloxane having the formula (1) or (2):in which A is a radical having the structural formula (I):

Priority: US2000-0740063 Applic. Date: 2000-12-20; FR1997-0015309 Applic. Date: 1997-12-04; US1998-0205607 Applic. Date: 1998-12-04

Inventor: LEDUC MADELEINE (FR); RICHARD HERVE (FR); LAGRANGE ALAIN (FR)


Patent No.: US 6379655 B1 Issued: 2002-04- 30

Title: Photoprotective/cosmetic compositions comprising aminoamidine sunscreens

Applicant: OREAL (FR)

Application No.: US2000-0722473 Applic. Date: 2000-11-28

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-irradiation, particularly solar radiation, comprise an effective UV-photoprotecting amount of at least one characteristically novel aminoamidine compound, advantageously having the structural formula (I):formulated into a topically applicable, cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: FR1999-0014999 Applic. Date: 1999-11-29

Inventor: BRETON PHILIPPE (FR)


Patent No.: US 6383767 B1 Issued: 2002-05-07

Title: Luminescent in vivo glucose measurement

Applicant: MOTOROLA INC (US)

Application No.: US2000-0489372 Applic. Date: 2000-01-21

Abstract: A luminescent in vivo glucose measurement method and apparatus is provided. The luminescent in vivo glucose measurement method includes the steps of illuminating displaced luminescent molecules with illuminating light, the displaced luminescent molecules and associated captive glucose analogue molecules being contained within an implanted luminescent in vivo measurement apparatus implanted within the interstitial fluid of the subject, and measuring an emitted light, the emitted light being emitted in response to the illumination, wherein the emitted light is related to the glucose level in the interstitial fluid.

Priority: US2000 -0489372 Applic. Date: 2000-01-21

Inventor: POLAK ANTHONY J (US)


Patent No.: US 6395284 B1 Issued: 2002-05- 28

Title: Immobilization of vitamin A acid by cationic polyelectrolytes

Applicant: MAX PLANCK GESELLSCHAFT (DE)

Application No.: US2000-0492003 Applic. Date: 2000-01-27

Abstract: Mesomorphic complexes of vitamin A acid and cationic polyelectrolytes, their preparation and use. The cationic polyelectrolyte, for example PDADMAC, PM4VP, poly (ionene-6,3), polyethyleneimine or a poly-L-amino acid, is mixed with vitamin A acid to produce mesomorphic complexes. Uses of these mesomorphic complexes include the transport of vitamin A in the human body, the treatment of severe cases of acne externally, courses of skin rejuvenation, and the inhibition of malignant tumors.

Priority: DE1997-1032139 Applic. Date: 1997-07-25; WO1998-EP04644 Applic. Date: 1998-07-24

Inventor: THUNEMANN ANDREAS (DE)


Patent No.: US 6395301 B1 Issued: 2002-05-28

Title: Anhydrous hydrophobic cosmetic composition in the form of a compact powder

Applicant: OREAL (FR)

Application No.: US1999-0476784 Applic. Date: 1999-12-30

Abstract: An anhydrous hydrophobic cosmetic composition in the form of a compact powder which can be taken up in dry form or with water, comprising a particulate phase comprising hydrophilic pulverulent compounds, wherein the hydrophilic pulverulent compounds represent 20 to 35% by weight relative to the total weight of the particulate phase. The invention also relates to a make-up process using such a composition, as well as to a device comprising such a composition and a sponge which can be moistened.

Priority: FR1998-0016662 Applic. Date: 1998-12-30

Inventor: CANTIN HERVE (FR)


Patent No.: US 6399700 B2 Issued: 2002-06-04
Publication No.: US20010027237A1 Published: 2001-10-04

Title: Comb copolymers for regulating cell-surface interactions

Applicant: MASSACHUSETTS INST TECHNOLOGY (US)

Application No.: US2001-0817887 Applic. Date: 2001-03-26

Abstract: Synthetic comb copolymers which elicit controlled cellular response, methods of applying these polymers to various surfaces, and methods of using the polymers for modifying biomaterial surfaces, in tissue engineering applications and as drug delivery devices are provided. The comb copolymers are comprised of hydrophobic polymer backbones and hydrophilic, non-cell binding side chains which can be end-capped with cell-signaling ligands that guide cellular response. By mixing non-cell binding combs with ligand- bearing combs, the surface concentration and spatial distribution of one or more types of ligands, including adhesion peptides and growth factors, can be tuned on a surface to achieve desired cellular response. In one embodiment, the combs are used as stabilizing agents for dispersion polymerization of latexes.; The comb-stabilized latexes can be applied to substrates by standard coating operations to create a bioregulating surface, or used as drug delivery agents. In another embodiment, the combs can be blended in small quantities to a hydrophobic matrix polymer and processed to affect the surface segregation of the comb. The comb copolymers are formed in one embodiment by providing a biodegradable polyester backbone that includes reactive groups, and reacting the reactive groups in the backbone with reactive chain ends on a low molecular weight hydrophilic polymer. In another embodiment, non- biodegradable comb copolymers are formed by free radical synthesis of a hydrophobic monomer and a hydrophilic macromonomer.; In all of the above embodiments, a portion of the hydrophilic polymer side chains can be covalently coupled to cell-signaling ligands such as adhesion peptides or growth factors to control cellular response.

Priority: US2001-0817887 Applic. Date: 2001-03-26; US2000- 0634095 Applic. Date: 2000-08-08; US1999-0290140 Applic. Date: 1999-04-13; US1998-0081596P Applic. Date: 1998-04-13

Inventor: MAYES ANNE M (US); GRIFFITH LINDA G (US); IRVINE DARRELL J (US); BANERJEE PALLAB (US); JOHNSON TERRY D (US)


Patent No.: US 6403061 B1 Issued: 2002-06- 11

Title: UV-photoprotecting W/O emulsions comprising micronized insoluble screening agents & nonscreening oxyalkylenated silicones

Applicant: L OREAL SOC (FR)

Application No.: US2000-0693888 Applic. Date: 2000-10-23

Abstract: Topically applicable, water-resistant cosmetic/dermatological water-in-oil (W/O) emulsions well suited for the UV-photoprotection of human skin and/or hair comprise (a) at least one aqueous phase and (b) at least one fatty phase, (c) an effective UV-photoprotecting amount of at least one micronized organic UV -screening agent insoluble therein, the mean particle size of such micronized particles ranging from 0.01 to 2 mum, and (d) at least one oxyalkylenated non-UV-screening organomodified silicone.

Priority: FR1999-0013219 Applic. Date: 1999-10-22

Inventor: CANDAU DIDIER (FR); FORESTIER SERGE (FR)


Patent No.: US 6403125 B1 Issued: 2002-06-11

Title: Utilization of an extract of a plant of the Cecropia genus

Applicant: COGNIS FRANCE SA (FR)

Application No.: US2001-0868722 Applic. Date: 2001-06-21

Abstract: The utilization of at least one extract of a plant belonging to the cecropia genus as an active agent. The extract is used alone or in conjunction with at least one other active agent for preparing a cosmetic or dermopharmaceutical product or a cosmetic or dermopharmaceutical composition for external local application on the skin, the mucous membranes and/or the epithelial or body appendage formations.

Priority: WO1999-EP10031 Applic. Date: 1999-12-16; FR1998-0016289 Applic. Date: 1998-12-21

Inventor: PAULY GILLES (FR); MORETTI CHRISTIAN (FR)


Patent No.: US 6403653 B1 Issued: 2002-06- 11

Title: Active topical skin protectants using reactive nanoparticles

Applicant: US ARMY (US); NANOSCALE MATERIALS INC (US)

Application No.: US2001-0871747 Applic. Date: 2001-06-01

Abstract: A topical skin protectant formulation containing a barrier cream and an active moiety for protecting warfighters and civilians against all types of harmful chemicals, specifically chemical warfare agents (CWA's). The topical skin protectant offers a barrier property and an active moiety that serves to neutralize chemical warfare agents into less toxic agents.

Priority: US2001-0871747 Applic. Date: 2001-06-01; US2000-0209337P Applic. Date: 2000-06-02

Inventor: HOBSON STEPHEN T (US); BRAUE JR ERNEST H (US); LEHNERT ERICH K (US); KLABUNDE KENNETH J (US); KOPER OLGA P (US); DECKER SHAWN (US)


Patent No.: US 6406685 B1 Issued: 2002-06-18

Title: Cosmetic composition comprising a compound such as indigoid

Applicant: OREAL USA L (FR)

Application No.: US2000-0554932 Applic. Date: 2000-06-13

Abstract: A cosmetic composition comprising, in a cosmetically acceptable medium, at least one compound of formula (I)in which R1, and R'1 are chosen from alkyl radicals and R2, R'2, R3, R'3, R4, R'4, R5, and R'5 are chosen from a hydrogen atom, a halogenated radical, a hydroxyl radical, an alkyl, alkyloxy, acyl, or acyloxy radical having 1 to 6 carbon atoms. The use of compounds of formula (I) for coating substrate particles, the resulting powder substance, and its use in a cosmetic composition.

Priority: FR1997-0014656 Applic. Date: 1997-11-21; WO1998-FR02411 Applic. Date: 1998-11-12

Inventor: PHILIPPE MICHEL (FR); HENRION JEAN- CHRISTOPHE (FR); GUILLIER-BERTEUIL NATHALIE (FR)


Patent No.: US 6409998 B1 Issued: 2002-06- 25

Title: UV-photoprotecting emulsions comprising micronized insoluble screening agents and associative polymers

Applicant: L OREAL SOC (FR)

Application No.: US2000-0693889 Applic. Date: 2000-10-23

Abstract: Topically applicable, water- resistant cosmetic/dermatological emulsions well suited for the UV-photoprotection of human skin and/or hair contain an effective UV-photoprotecting amount of at least one micronized organic UV-screening agent insoluble therein, the mean particle size of such micronized particles ranging from 0.01 to 2 mum, and further containing at least one associative polymer which is characteristically other than a C8-C16 alkyl polyglucoside.

Priority: FR1999-0013220 Applic. Date: 1999-10- 22

Inventor: CANDAU DIDIER (FR); FORESTIER SERGE (FR); PISSON ANNE-MARIE (FR)


Patent No.: US 6409999 B2 Issued: 2002-06-25
Publication No.: US20010041167A1 Published: 2001-11-15

Title: Synergistically UV-photoprotecting benzotriazole-substituted silicon/cinnamic acid compositions

Applicant: L OREAL SOC (FR)

Application No.: US2001-0796636 Applic. Date: 2001-03-02

Abstract: Topically applicable cosmetic/dermatological compositions suited for improvedly UV-photoprotecting human skin and/or hair against the deleterious effects of ultraviolet irradiation, advantageously oil-in-water emulsions, contain SPF-synergistically enhancing amounts of (a) at least one UV-screening benzotriazole-substituted silicon compound and (b) at least one UV-screening cinnamic acid derivative, formulated into (c) a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.

Priority: FR1999-0008568 Applic. Date: 1999-07-02; WO2000-FR01696 Applic. Date: 2000-06- 20

Inventor: AGOSTINI ISABELLE (FR); ARNAUD PASCAL (FR); GUILLARD SYLVIE (FR)


Patent No.: US 6410603 B1 Issued: 2002-06-25

Title: Active topical skin protectants using combinations of reactive nanoparticles and polyoxometalates or metal salts

Applicant: US ARMY (US); NANOSCALE MATERIALS INC (US); UNIV EMORY (US)

Application No.: US2001-0871744 Applic. Date: 2001-06-01

Abstract: A topical skin protectant formulation containing a barrier cream and a active moiety for protecting warfighters and civilians against all types of harmful chemicals, specifically chemical warfare agents (CWAs). The topical skin protectant offers a barrier property and an active moiety that serves to neutralize chemical warfare agents into less toxic agents.

Priority: US2001-0871744 Applic. Date: 2001-06-01; US2000-0209337P Applic. Date: 2000-06-02

Inventor: HOBSON STEPHEN T (US); BRAUE ERNEST H (US); LEHNERT ERICH K (US); KLABUNDE KENNETH J (US); DECKER SHAWN (US); HILL CRAIG L (US); RHULE JEFFREY (US); BORING ERIC (US); KOPER OLGA (US)


Patent No.: US 6413527 B1 Issued: 2002-07-02

Title: Nanoemulsion based on alkyl ether citrates and its uses in the cosmetics, dermatological, pharmacological and/or ophthalmological fields

Applicant: OREAL (FR)

Application No.: US2000-0478408 Applic. Date: 2000-01-06

Abstract: A nanoemulsion, the oil globules of which have an average size of less than 100 nm, comprising an anionic surfactant chosen from alkyl ether citrates and at least one oil having a molecular weight of greater than 400, the ratio by weight of the amount of oily phase to the amount of surfactant ranging from 2 to 10. The emulsion obtained is transparent and stable on storage. It can comprise large amounts of oil while retaining good transparency and while having good cosmetic properties. It can constitute a composition for topical use, a pharmaceutical composition or an ophthalmological composition. The invention also relates to the use of the nanoemulsion according to the invention in the cosmetics and dermatological fields, in particular for moisturizing the skin and/or mucous membranes, as well as for treating the hair, and in the ophthalmological field, as an eye lotion for treating the eyes.

Priority: FR1999-0000408 Applic. Date: 1999-01- 14

Inventor: SIMONNET JEAN-THIERRY (FR); SONNEVILLE ODILE (FR); LEGRET SYLVIE (FR)


Patent No.: US 6416748 B1 Issued: 2002-07-09

Title: Emulsifier-free UV-photoprotecting emulsions comprising micronized insoluble screening agents

Applicant: L OREAL SOC (FR)

Application No.: US2000-0693894 Applic. Date: 2000-10-23

Abstract: Topically applicable, water-resistant but emulsifier-free cosmetic/dermatological emulsions well suited for the UV- photoprotection of human skin and/or hair contain (a) at least one aqueous phase and (b) at least one fatty phase, (c) an effective UV-photoprotecting amount of at least one micronized organic UV-screening agent insoluble therein, the mean particle size of such micronized particles ranging from 0.01 to 2 mum and (d) optionally, at least one crosslinked polymer of at least one ethylenically unsaturated monomer.

Priority: FR1999-0013221 Applic. Date: 1999-10-22

Inventor: CANDAU DIDIER (FR); PISSON ANNE-MARIE (FR)


Patent No.: US 6419946 B1 Issued: 2002-07-16

Title: Nanoemulsion based on mixed esters of a fatty acid or of a fatty alcohol, of a carboxylic acid and of a glycerol and its uses in the cosmetics, dermatological and/or ophthalmological fields

Applicant: OREAL (FR)

Application No.: US1999-0459581 Applic. Date: 1999-12-13

Abstract: A nanoemulsion, the oil globules of which have a number-average size of less than 100 nm, comprising a surfactant chosen from mixed esters of a fatty acid or of a fatty alcohol, of a carboxylic acid and of glycerol and at least one oil having a molecular weight of greater than 400, the ratio by weight of the amount of oily phase to the amount of surfactant ranging from 2 to 10. The nanoemulsion may be used in, for example, the cosmetics and dermatological fields, in particular for moisturizing the skin and/or mucous membranes, as well as for treating the hair, and in the ophthalmological field, as an eye lotion for treating the eyes.

Priority: FR1998-0015764 Applic. Date: 1998-12- 14

Inventor: SONNEVILLE ODILE (FR); SIMONNET JEAN-THIERRY (FR); LEGRET SYLVIE (FR)


Patent No.: US 6426503 B1 Issued: 2002-07-30

Title: Opto-electronic ultra-violet radiation dosimeter

Applicant: SOUTHWEST RES INST (US)

Application No.: US2000-0591477 Applic. Date: 2000-06-09

Abstract: A dosimeter 10, which may be easily implemented as a monolithic device, using all-silicon semiconductor fabrication techniques. The dosimeter 10 has a UV filter 11a, whose transmission characteristics match those of the erythema action curve. The filtered radiation is detected by a photodiode, and appropriate signal processing is performed to provide some sort of output indicating UV dosage. Other embodiments use a UV sensitive photodiode without a filter.

Priority: US2000-0591477 Applic. Date: 2000-06-09

Inventor: WUEEST MARTIN P (US)


Patent No.: US 6428814 B1 Issued: 2002-08-06
Publication No.: US20020068092A1 Published: 2002-06- 06

Title: BIOADHESIVE NANOPARTICULATE COMPOSITIONS HAVING CATIONIC SURFACE STABILIZERS

Applicant: ELAN PHARMA INT LTD (IL)

Application No.: US1999- 0414159 Applic. Date: 1999-10-08

Abstract: Bioadhesive nanoparticulate compositions, comprising active agent particles and one or more cationic surface stabilizers, are described. The cationic surface stabilizers prevent aggregation of the nanoparticles and increase bioadhesion of the nanoparticles to biological substrates, such as an insect, teeth, bone, nails, chitin, feathers, scales, mucous, skin, hair, plant tissue, etc. The particles may consist of pharmacologically active compounds (e.g., drug compounds for human or veterinary use), agricultural chemicals (pesticides, herbicides, fertilizers, and the like), cosmetic agents, consumer products (coloring agents, flavors, or fragrances), or other materials which function by interacting with biological substrates. In addition, the invention relates to methods of preparing and using such bioadhesive nanoparticulate compositions.

Priority: US1999-0414159 Applic. Date: 1999-10- 08

Inventor: BOSCH H WILLIAM (US); COOPER EUGENE R (US); MCGURK SIMON L (US)


Patent No.: US 6436094 B1 Issued: 2002-08-20

Title: Electromagnetic and laser treatment and cooling device

Applicant: LASERSCOPE INC (US)

Application No.: US2000-0527052 Applic. Date: 2000-03-16

Abstract: An apparatus for lowering the temperature of skin on a patient during treatment applying electromagnetic energy to the skin comprising a window of a first thermally conductive material through which electromagnetic energy can pass for placement against the epidermis of the skin. A reservoir of coolant is spaced from an edge of the window. A non-flowing second thermally conductive material connects the window and the reservoir to transfer heat from the window to the coolant in the reservoir.

Priority: US2000-0527052 Applic. Date: 2000-03- 16

Inventor: REUTER ERIC M (US)


Patent No.: US 6454974 B1 Issued: 2002-09- 24

Title: Method for vacuum pressure forming reinforced plastic articles

Applicant: MAGNA INTERNAT OF AMERICA INC (US)

Application No.: US2001-0857768 Applic. Date: 2001-06-11

Abstract: A method for thermoforming a reinforced article, comprising: providing a reinforced plastic sheet comprising at least one thermoplastic material and reinforcement nanoparticles dispersed within the at least one thermoplastic material, the reinforcement particles comprising less than 15% of a total volume of the plastic sheet, at least 50% of the reinforcement particles having a thickness of less than about 20 layers, and at least 99% of the reinforcement particles having a thickness of less than about 30 layers; preheating said plastic sheet; communicating said preheated plastic sheet to a first mold assembly having a first mold cavity defined by mold surfaces, the mold surfaces corresponding to a configuration of the article to be molded, an amount of the plastic sheet communicated to the first mold assembly being sufficient to form a skin of the article; applying a vacuum to one side of the first mold assembly while concurrently applying pressurized gas to an opposing side of the first mold assembly so as to force said heated plastic sheet into conformity with the mold surfaces; cooling the conformed plastic sheet; transferring the conformed plastic sheet to a second mold assembly; introducing to the conformed plastic sheet a reinforced plastic melt made from material identical or different from that of the plastic sheet, said plastic melt having a blowing agent to achieve volume expansion and the production of a cellular reticulate structure; cooling said plastic melt to form a solidified plastic member adhered to said conformed plastic sheet, said conformed plastic sheet and said adhered solidified plastic member together comprising said article; and removing said article from said second mold assembly.

Priority: US2001-0857768 Applic. Date: 2001-06-11; US1998-0113064P Applic. Date: 1998-12-21; WO1999-US29987 Applic. Date: 1999-12-17

Inventor: WILSON PHILLIP S (US)


Patent No.: US 6461625 B1 Issued: 2002-10-08

Title: Nanoemulsion based on alkoxylated alkenyl succinates or alkoxylated alkenyl succinates of glucose and its uses in the cosmetics, dermatological, opthalmological and/or pharmaceutical fields

Applicant: OREAL (FR)

Application No.: US2000- 0489839 Applic. Date: 2000-01-24

Abstract: A nanoemulsion, the oil globules of which have an average size of less than 100 nm, comprising a surfactant chosen from the alkoxylated alkenyl succinates, the alkoxylated alkenyl succinates of glucose and the alkoxylated alkenyl succinates of methylglucose, and at least one oil having a molecular weight of greater than 400, the ratio by weight of the amount of oily phase to the amount of surfactant ranging from 2 to 10. The emulsion obtained is transparent and stable on storage. It can comprise large amounts of oil while retaining good transparency and while having good cosmetic properties. It can constitute a composition for topical use, a pharmaceutical composition or an ophthalmological composition.

Priority: FR1999-0001145 Applic. Date: 1999-02-02

Inventor: SIMONNET JEAN-THIERRY (FR); SONNEVILLE ODILE (FR); LEGRET SYLVIE (FR)


Patent No.: US 6464990 B2 Issued: 2002-10-15
Publication No.: US20020015721A1 Published: 2002-02- 07

Title: NANOEMULSION BASED ON ETHYLENE OXIDE AND PROPYLENE OXIDE BLOCK COPOLYMERS AND ITS USES IN THE COSMETICS, DERMATOLOGICAL AND/OR OPHTHALMOLOGICAL FIELDS

Applicant: OREAL (FR)

Application No.: US2000-0477715 Applic. Date: 2000-01- 05

Abstract: A nanoemulsion comprising an oily phase dispersed in an aqueous phase and having oil globules with a number-average size of less than 100 mm, which dispersion is facilitated by a surfactant comprised of polyethylene oxide and polypropylene oxide blocks, the oily phase comprising at least one oil having a molecular weight of greater than 400 and wherein the ratio by weight of the amount of oily phase to the amount of surfactant ranges from 2 to 10.

Priority: FR1999- 0000031 Applic. Date: 1999-01-05

Inventor: SIMONNET JEAN-THIERRY (FR); SONNEVILLE ODILE (FR); LEGRET SYLVIE (FR)


Patent No.: US 6471949 B2 Issued: 2002-10-29
Publication No.: US20020064507A1 Published: 2002-05-30

Title: Compositions comprising at least one UV screening agent and at least one flavylium salt which is unsubstituted in position 3, for coloring the skin, and uses thereof

Applicant: OREAL (FR)

Application No.: US2001-0901724 Applic. Date: 2001-07-11

Abstract: A cosmetic and/or dermatological composition intended for artificially coloring the skin, which comprises, in, for example, a cosmetically acceptable support, at least one compound capable of screening out ultraviolet radiation and at least one flavylium salt compound which is unsubstituted in position 3, and which is substituted with at least one radical chosen from hydroxyl and alkoxy radicals, wherein the at least one flavylium salt compound may be obtained, for example, in a manner chosen from synthetically, from a plant extract containing it, and from an enriched plant extract containing it. The invention also relates to the uses of these compositions for coloring the skin.

Priority: FR2000-0009117 Applic. Date: 2000-07-12

Inventor: CANDAU DIDIER (FR); FORESTIER SERGE (FR)


Patent No.: US 6473190 B1 Issued: 2002-10-29

Title: Optical volume sensor

Applicant: BAYER AG (US)

Application No.: US2000-0523716 Applic. Date: 2000-03-13

Abstract: An optical sensor for measuring the volume of an object, the object having a top and a side. The optical sensor comprises a source of light and a light sensor adapted to measure the amount of light reflected off the side and off the top of the object, wherein the measured amount of the light reflected off the side and the top of the object correlates to a height and a diameter of the object. At least one optical device is adapted to direct light reflected off the side of the object to the light sensor, and at least one optical device is adapted to direct light reflected off the top of the object to the light sensor.

Priority: US2000-0523716 Applic. Date: 2000-03-13

Inventor: DOSMANN ANDREW J (US)


Patent No.: US 6475474 B1 Issued: 2002-11- 05

Title: Use in cosmetic compositions of amphoteric surface-active agents for precipitating cationic polymers in the diluted state

Applicant: RHONE POULENC CHIMIE (FR)

Application No.: US2000-0600371 Applic. Date: 2000-07-14

Abstract: The invention relates to the use of at least one amphoteric in transparent aqueous cosmetic compositions for the hair and/or the skin designed to be rinsed, comprising at least one anionic surface-active agent, at least one surface-active agent selected for the betaines and at least one water-soluble or water dispersible cationic polymer derived from a polysaccharide (PolC), as precipitant, in the diluted state, of said cationic polymer (PolC). The invention further relates to transparent aqueous cosmetic compositions for the hair and/or skin designed to be rinsed, comprising at least one one anionic surface-active agent, at least one surface-active agent selected for the betaines, at least one water- soluble or water dispersible cationic polymer derived from a polysaccharide (PolC), and at least one amphoteric surface-active agent.

Priority: FR1998-0000634 Applic. Date: 1998-01-19; WO1999-FR00073 Applic. Date: 1999-01-15

Inventor: RICCA JEAN-MARC (FR)


Patent No.: US 6485950 B1 Issued: 2002-11- 26

Title: Isozyme of autoclavable superoxide dismutase (SOD), a process for the identification and extraction of the SOD in cosmetic, food and pharmaceutical compositions

Applicant: COUNCIL SCIENT IND RES (IN)

Application No.: US2000 -0617118 Applic. Date: 2000-07-14

Abstract: The invention relates to a novel purified isozyme of an autoclavable superoxide dismutase extracted from the plant Potentilla atrosanguinea Lodd. Var. orgyrophylla, said isozyme having the following characteristics, O2- scavenging activity remains same before and after autoclaving; scavenges O2- from sub-zero temperature of -20 DEG C. to high temperature of +80 DEG C.; O2- scavenging activity at 25 DEG C. for 30 days without adding any stabilizing agent such as polyols or sugars; O2- scavenging activity in the presence of saline (0.9% sodium chloride) to 61.8% of the control (without 0.9% sodium chloride), stable at 4 DEG C. for at least 8 months; contamination free and infection free from any living micro- and/or macro-organism after autoclaving; possesses temperature optima at 0 DEG C.; possesses a molecular weight of 33 kD under non- denaturating conditions; possesses a molecular weight of 36 kD under denaturating conditions; has clear peaks in UV range at 268 and 275 nm; has an enzyme turnover number of 19.53x104% per nmol per min at 0 DEG C.; and requires Cu/Zn as a co-factor, method for the preparation of the purified isozyme of autoclavable superoxide dismutase and formulations containing the said autoclavable superoxide dismutase.

Priority: US2000-0617118 Applic. Date: 2000-07-14

Inventor: KUMAR SANJAY (IN); SAHOO RASHMITA (IN); AHUJA PARAMVIR SINGH (IN)


Patent No.: US 6486147 B2 Issued: 2002-11-26
Publication No.: US20010044430A1 Published: 2001-11-22

Title: Cosmetic composition containing a steroid and a 2-alkylalkanol or an ester thereof

Applicant: OREAL (FR)

Application No.: US2001-0828813 Applic. Date: 2001-04-10

Abstract: A composition including at least one steroid chosen from DHEA and/or a biological precursor and/or a chemical or metabolic derivative of the latter, characterized in that it additionally comprises at least one 2-alkylalkanol comprising from 12 to 36 carbon atoms or an ester of such an alcohol. The invention also relates to the cosmetic and dermatological uses of this composition, in particular for preventing or treating chronological or actinic ageing and canities.

Priority: FR2000-0004576 Applic. Date: 2000-04-10

Inventor: BALDO FRANCINE (FR); DREHER SUSANNE (FR)


Patent No.: US 6488952 B1 Issued: 2002-12- 03

Title: Semisolid therapeutic delivery system and combination semisolid, multiparticulate, therapeutic delivery system

Application No.: US2001-0941378 Applic. Date: 2001-08-28

Abstract: A semisolid therapeutic delivery system and combination semisolid, multiparticulate therapeutic delivery system for therapeutic applications is provided which includes a biocompatible semisolid delivery system and a biocompatible combination semisolid, multiparticulate delivery system for injection, deposition, or implantation within the body to facilitate local or systemic therapeutic effects through the actions of incorporated medicaments or actions inherit to the system.

Priority: US2001-0941378 Applic. Date: 2001-08- 28

Inventor: KENNEDY JOHN P (US); JONES II CURTIS E (US)


Patent No.: US 6495596 B1 Issued: 2002-12-17
Publication No.: US20020198260A1 Published: 2002-12-26

Title: Compounds and methods for inhibition of phospholipase A2 and cyclooxygenase-2

Applicant: BIOZONE LAB INC (US)

Application No.: US2001-0877334 Applic. Date: 2001-06-07

Abstract: The present invention comprises a group of related lipid molecules, and methods for their use, that maybe used to treat inflammation and certain inflammation related diseases. The group of related lipid molecules are capable of inhibiting certain enzyme systems including phospholipase A2, and cyclooxygenase-2. The group of related lipid molecules of the invention may be characterized by specific structural characteristics, or by specific biological activity, including inhibition of the previously listed enzymes.

Priority: US2001-0877334 Applic. Date: 2001-06-07; US2001-0278257P Applic. Date: 2001-03-23

Inventor: KELLER BRIAN (US)


Patent No.: US 6500446 B1 Issued: 2002-12- 31

Title: Compositions which contain at least one cationic polymer and at least one active molecule contained in at least one micro or nonopartculate vector, and their use for treating living or inert surfaces

Applicant: VIRBAC (FR)

Application No.: US1998-0059200 Applic. Date: 1998-04-14

Abstract: The present invention relates to compositions which contain at least one cationic polymer and at least one active molecule contained in at least one micro or nanoparticulate vector, and their use for treating living or inert surfaces.

Priority: FR1997-0004549 Applic. Date: 1997-04-14

Inventor: DERRIEU GUY (FR); POUGNAS JEAN-LUC (FR); MONGINOUX PATRICIA (FR); KARST CHRISTIAN (FR)


Patent No.: US 6505059 B1 Issued: 2003-01-07

Title: Non-invasive tissue glucose level monitoring

Applicant: GEN HOSPITAL CORP (US)

Application No.: US1999-0287486 Applic. Date: 1999-04- 06

Abstract: Instruments and methods for performing non-invasive measurements of analyte concentrations and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.

Priority: US1999-0287486 Applic. Date: 1999-04-06; US1998-0080794P Applic. Date: 1998-04-06

Inventor: KOLLIAS NIKIFOROS (US); TIAN WEI DONG (US); FREEMAN JENNY E (US)


Patent No.: US 6506796 B1 Issued: 2003-01-14

Title: Use of a RAR-gamma-specific agonist ligand for increasing the rate of apoptosis

Applicant: GALDERMA RECH DERMATOLOGIQUE (FR)

Application No.: US2000-0624771 Applic. Date: 2000-07-25

Abstract: Methods of cosmetically or therapeutically treating diseases or disorders in cell populations whose pathology is linked to an inadequate rate of apoptosis by administering a therapeutically effective amount of 6-3-(1-adamantyl)-4 -hydroxyphenyl)-2-naphthanoic acid.

Priority: FR1995-0012179 Applic. Date: 1995-10- 09

Inventor: FESUS LASZLO (HU); SZONDY ZSUZSA (HU); REICHERT UWE (FR)


Patent No.: US 6509008 B1 Issued: 2003-01- 21

Title: Solubilization of 1,3,5-triazine derivatives with N-acyl amino acid esters

Applicant: OREAL (FR)

Application No.: US2002-0178339 Applic. Date: 2002-06-25

Abstract: A composition comprising at least one 1,3,5-triazine derivative and at least one N-acyl amino acid ester and its use in or for the manufacture of compositions, especially cosmetic and dermatological compositions for protecting the skin and/or the lips and/or integuments against ultraviolet radiation, in particular solar radiation. In addition, a cosmetic treatment process comprising the application of the cosmetic composition, and the use of the at least one N-acyl amino acid ester, in anti-sun compositions containing a 1,3,5-triazine derivative to improve the sun protection factor of the composition.

Priority: FR2001-0008426 Applic. Date: 2001-06-26

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6511670 B1 Issued: 2003-01- 28

Title: (poly)thiaalkynoic compounds and pharmaceutical/cosmetic compositions comprised thereof

Applicant: OREAL (FR)

Application No.: US2000-0548932 Applic. Date: 2000-04-13

Abstract: Novel pharmaceutically/cosmetically-active (poly) thiaalkynoic compounds have the structural formula (I):and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example inflammation disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

Priority: FR1999- 0004745 Applic. Date: 1999-04-15

Inventor: MAIGNAN JEAN (FR); GENARD SYLVIE (FR); MICHEL SERGE (FR)


Patent No.: US 6511684 B1 Issued: 2003-01-28

Title: Use of plant extracts with an anti-radical-type action

Applicant: COGNIS FRANCE SA (FR)

Application No.: US2001-0857445 Applic. Date: 2001-06-04

Abstract: The use of plant extracts, especially plant extracts with an anti-radical-type action, and a cosmetic or dermo-pharmaceutical composition containing extracts of this type. The use of at least one plant extract whose botanical genus belongs to the group formed by the following: Clidemia, Inga, Sabicea, Astrocaryum, Siparuna, Eperua, Byrsonima, Priva, Coutoubea and Goupia genera; as an active substance which has especially anti-radical-type activities, for preparing a cosmetic or dermopharmaceutical product for local, external use for the skin, the mucous membranes and/or the epithel or appendage structures.

Priority: WO1999-EP09294 Applic. Date: 1999-11-30; FR1998-0015380 Applic. Date: 1998-12-03

Inventor: PAULY GILLES (FR); MORETTI CHRISTIAN (FR)


Patent No.: US 6517820 B1 Issued: 2003-02-11

Title: Cosmetic composition in the form of a powder comprising a specific ester

Applicant: OREAL (FR)

Application No.: US2000-0518136 Applic. Date: 2000-03-03

Abstract: The present invention relates to a cosmetic composition in the form of a powder containing a particulate phase and a fatty phase, characterized in that the fatty phase contains at least one fatty acid ester or at least one fatty alcohol ester, the carbonaceous chain of the fatty acid or alcohol being branched and saturated, and containing 24 to 28 carbon atoms. It also relates to the cosmetic applications of such a composition.

Priority: FR1999-0002705 Applic. Date: 1999-03-04

Inventor: ROBERT VALERIE (FR)


Patent No.: US 6521237 B2 Issued: 2003-02-18
Publication No.: US20020048591A1 Published: 2002-04- 25

Title: SKIN CARE COMPOSITION

Applicant: JOHNSON & JOHNSON CONSUMER (US)

Application No.: US1999-0325452 Applic. Date: 1999-06- 03

Abstract: There are provided compositions which include a retinoid and preferably retinol; an acid; and an acid neutralizing effective amount of ammonium hydroxide. There are also provided compositions which include a retinoid and a neutralized ammonium salt of an acid. Further provided are methods for reducing fine lines and wrinkles and for increasing the clarity of a skin surface, cellular turnover, skin radiance, skin smoothness, skin permeation or collagen synthesis in a mammal in need thereof. Compositions as described above are administered topically to the skin of the animal.

Priority: US1999-0325452 Applic. Date: 1999-06-03; US1998-0107956P Applic. Date: 1998-11-12

Inventor: COLE CURTIS A (US); FLACK LAURA E (US); KAMINSKI CLAUDIA (US)


Patent No.: US 6524595 B1 Issued: 2003-02-25

Title: Cyclodextrins preferentially substituted on their primary face by acid or amine functions

Applicant: COLETICA (FR)

Application No.: US2000-0613773 Applic. Date: 2000-07-11

Abstract: Non-hydroxyalkylated cyclodextrins are disclosed wherein at least one primary alcohol function (CH2OH) is substituted, the - OH portion being replaced by a substituent with formula -O-CO-R or -NR1R2, where:R, R1 and R2 independently represent a linear or cyclic, saturated or unsaturated, hydroxylated or non-hydroxylated alkyl group containing 1 to 30 carbon atoms, preferably 1 to 22 carbon atoms, more preferably a fatty chain containing 2 to 22 carbon atoms. These cyclodextrins are used as vectors for at least one active ingredient, in particular to encourage tissue penetration, in a cosmetic application, or for the production of pharmaceutical compositions, in particular dermopharmaceuticals.

Priority: FR2000-0006102 Applic. Date: 2000-05-12

Inventor: PERRIER ERIC (FR); TERRY NICOLAS (FR); RIVAL DELPHINE (FR); COLEMAN ANTHONY WILLIAM (FR)


Patent No.: US 6531117 B2 Issued: 2003-03-11
Publication No.: US20010022965A1 Published: 2001-09-20

Title: Aqueous dispersion of water- insoluble organic UV filter substances

Applicant: BASF AG (DE)

Application No.: US2001-0771594 Applic. Date: 2001-01-30

Abstract: The invention relates to aqueous dispersions of sparingly water-soluble or water-insoluble organic UV filter substances, which comprise at least one sparingly water-soluble or water-insoluble organic UV filter substance as colloidally disperse phase in amorphous or partially amorphous form.

Priority: DE2000- 1007116 Applic. Date: 2000-02-17; DE2000-1042444 Applic. Date: 2000-08-29

Inventor: HEGER ROBERT (DE); AUWETER HELMUT (DE); DAUSCH WILMA M (DE); ZWISSLER GEORG KONRAD (DE); WUENSCH THOMAS (DE); WUNSCH THOMAS (DE)


Patent No.: US 6539252 B1 Issued: 2003-03-25

Title: Method and apparatus for the treatment of blood borne pathogens such as immunodeficiency virus

Applicant: BURRIS PHILLIP F (US)

Application No.: US2000-0491782 Applic. Date: 2000-01-26

Abstract: A method and apparatus for destroying blood borne pathogens is disclosed which utilizes a low intensity direct current to generate positive particles from various metals which destroy viral pathogens. A first electrode comprised of a metal such as silver is inserted into a patient's venous system. Then, a second electrode is placed on the patient's exterior in the vicinity of the first electrode. A low intensity direct current is applied to the first metal electrode which releases silver cations to be bonded to the virus, resulting in the denaturing of the virus. The first electrode is placed in the venous system of the infected patient via a catheter.

Priority: US2000-0491782 Applic. Date: 2000-01-26; US1996-0708083 Applic. Date: 1996-08-30

Inventor: FIELDS CHARLES BRUCE (US); BURRIS PHILLIP F (US)


Patent No.: US 6540981 B2 Issued: 2003-04-01
Publication No.: US20010022963A1 Published: 2001-09- 20

Title: Light imaging contrast agents

Applicant: AMERSHAM HEALTH AS (NO); NYCOMED IMAGING AS A OSLO NORW (US)

Application No.: US2000-0732917 Applic. Date: 2000-12-11

Abstract: The present invention relates to the use of particulate materials as contrast agents in in vivo light imaging.

Priority: US2000-0732917 Applic. Date: 2000-12- 11; US1997-0984771 Applic. Date: 1997-12-04; US1997-0875645 Applic. Date: 1997-12- 17

Inventor: KLAVENESS JO (NO); FUGLASS BJORN (NO); RONGVED PAAL (NO); JOHANNESEN EDVIN (NO); HENDRICHS PAUL MARK (US); GUNTHER WOLFGANG HANS HEINRICH (US); BACON EDWARD RICHARD (US); TONER JOHN LUKE (US); MCINTIRE GREGORY LYNN (US); DESAI VINAY C (US); RONGVED PAL (NO); HENRICHS PAUL MARK (US)


Patent No.: US 6541018 B1 Issued: 2003-04-01

Title: Nanoemulsion based on glycerol fatty esters, and its uses in the cosmetics, dermatological and/or ophthalmological fields

Applicant: OREAL (FR)

Application No.: US1999-0461753 Applic. Date: 1999-12- 16

Abstract: The present invention provides a nanoemulsion, that includes:an oily phase dispersed in an aqueous phase; andat least one glycerol fatty ester surfactant which is solid at a temperature of less than or equal to 45 DEG C.;wherein the oily phase includes oil globules having a number-average size of less than 100 nm;wherein the oily phase includes at least one oil having a molecular weight of greater than 400; andwherein a weight ratio of the oily phase to the surfactant ranges from 2 to 10. The invention also provides a process for making the nanoemulsion and methods for its use. Ideally, the emulsion is transparent and stable on storage. It can ideally contain large amounts of oil while retaining good transparency and good cosmetic properties.; The nanoemulsion is particularly useful in the cosmetics and dermatological fields, in particular for moisturizing the skin and/or mucous membranes, as well as for treating the hair, and, in the ophthalmological field, as an eye lotion for treating the eyes.

Priority: FR1998-0015950 Applic. Date: 1998-12- 17

Inventor: SIMONNET JEAN-THIERRY (FR); SONNEVILLE ODILE (FR); LEGRET SYLVIE (FR)


Patent No.: US 6544255 B2 Issued: 2003-04-08
Publication No.: US20020022828A1 Published: 2002-02- 21

Title: Method of hair removal by transcutaneous application of laser light

Applicant: KERALASE LTD (CA); KERALASE LTD (US)

Application No.: US2001-0811177 Applic. Date: 2001-03-15

Abstract: A method of hair removal, used primarily for cosmetic purposes, comprising the transcutaneous use of laser light having a wavelength which targets the keratin components of hair, thus destroying the hair by photothermolysis without damage to surrounding skin or tissue; this primary method may be supplemented by the use of intrafollicular hair removal methods utilizing a second wavelength of light produced by the same source used to generate the primary light wavelength.

Priority: US2001-0811177 Applic. Date: 2001-03-15; US1999-0225398 Applic. Date: 1999-01-06; US1997-0832920 Applic. Date: 1997-04- 04

Inventor: STEWART BOB W (US)


Patent No.: US 6555095 B1 Issued: 2003-04- 29

Title: Topical compositions and methods of application

Applicant: AVON PROD INC (US)

Application No.: US2001-0017552 Applic. Date: 2001-12- 14

Abstract: There are topical emulsion compositions having a cosmetic drug or medicinal active, a novel compound of the present invention, and a vehicle. The novel compound is represented by a formula selected from the group consisting of L-A-H and A-L-H, wherein L is a lipophilic moiety, A is an aromatic moiety, and H is a hydrophilic moiety. Also provided are methods of emulsifying a composition; improving the photostability of a composition; and enhancing the effectiveness of a sunscreen composition.

Priority: US2001-0017552 Applic. Date: 2001-12-14

Inventor: GARRISON MARK S (US)


Patent No.: US 6562355 B1 Issued: 2003-05-13

Title: Comixture of dextran sulfate/escin for treating skin redness/edema and/or sensitive skin

Applicant: OREAL (FR)

Application No.: US2000-0684986 Applic. Date: 2000-10-10

Abstract: Comixtures of escin and dextran sulfate are effective for treating skin redness/edema and/or sensitive skin, particularly redness and/or edema around the eyes and most particularly bags and/or dark rings around the eyes.

Priority: FR1999-0012589 Applic. Date: 1999-10-08

Inventor: RENAULT BEATRICE (FR)


Patent No.: US 6562356 B2 Issued: 2003-05-13
Publication No.: US20010036450A1 Published: 2001-11-01

Title: Nanoemulsions comprising at least one amphiphilic lipid, at least one oil, and at least one polyethylene glycol (PEG) ester, and uses thereof

Applicant: OREAL (FR)

Application No.: US2001-0765564 Applic. Date: 2001-01- 22

Abstract: Oil-in-water nanoemulsions comprising oil globules with an average size of less than 150 nm and comprising at least one oil, at least one amphiphilc lipid, and at least one polyethylene glycol (PEG) derivative chosen from PEG esters and PEG ethers chosen from compounds of formula (I):in which:R1 is chosen from linear and branched, saturated and unsaturated alkyl groups comprising from 8 to 30 carbon atoms and linear and branched, saturated and unsaturated acyl groups comprising from 8 to 30 carbon atoms,R2 is chosen from a hydrogen atom, linear and branched, saturated and unsaturated alkyl groups comprising from 1 to 30 carbon atoms, and linear and branched, saturated and unsaturated acyl groups comprising from 1 to 30 carbon atoms, andn is a number ranging from 80 to 350. Processes comprising such oil-in-water nanoemulsions.

Priority: FR2000-0000794 Applic. Date: 2000-01-21

Inventor: VERITE CLAUDE (FR); CAZIN BENEDICTE (FR); DOUIN VERONIQUE (FR); AUBRUN ODILE (FR); SIMONNET JEAN-THIERRY (FR)


Patent No.: US 6563122 B1 Issued: 2003-05- 13

Title: Fluorescence detection assembly for determination of significant vegetation parameters

Applicant: DEUTSCH ZENTR LUFT & RAUMFAHRT (DE)

Application No.: US2001-0830697 Applic. Date: 2001-04-30

Abstract: A basic assembly configuration for determination of relevant vegetation parameters includes a high repetitive pulsed excitation laser (1) for the stimulation of chlorophyll fluorescence, a fluorescence detector (3) including an imaging and separation optic (4, 5), a trigger and delay electronic (6) to adjust the laser and appropriate detector timing and a detector electronic (7), consisting of a signal recording and processing module. The assembly can be used for determination of relevant vegetation parameters for agricultural, horticultural and greenhouse application.

Priority: WO1998-EP06815 Applic. Date: 1998-10-28

Inventor: LUEDEKER WILHELM (DE); GUENTHER KURT (DE); DAHN HANS-GUENTER (DE)


Patent No.: US 6572892 B1 Issued: 2003-06-03

Title: Cosmetic or dermopharmaceutical composition in the form of beads and methods for preparing same

Application No.: US2001-0719852 Applic. Date: 2001-03-19

Abstract: The invention concerns an anhydrous solid composition comprising at least a hydrophobic wax, an oil and talcum, having preferably the form of beads with size ranging from 1 to 10000 microns. The beads can contain a cosmetic or pharmaceutical active principle, pigments or an agri-food constituent. The invention also concerns the method for preparing said beads.

Priority: FR1998-0007612 Applic. Date: 1998-06-17; WO1999-FR01445 Applic. Date: 1999-06-16

Inventor: IOULALEN KARIM (FR); RAYNAL ROSANNE (FR)


Patent No.: US 6580348 B1 Issued: 2003-06- 17

Title: Flat magnetic core

Applicant: VACUUMSCHMELZE GMBH (US)

Application No.: US2001-0914019 Applic. Date: 2001-12-10

Abstract: A toroidal tape core is produced from magnetic sheets (1) which may have slits (4). In order to improve the behavior of the toroidal cores (3) at high frequencies, the magnetic sheets (1) have a high surface roughness. The surface roughness of each magnetic sheet (1) is at least equal to the skin penetration depth at the frequency being used.

Priority: DE1999-1007542 Applic. Date: 1999-02-22; WO2000-DE00300 Applic. Date: 2000-02-01

Inventor: HUNDT HARALD (DE); BEICHLER JOHANNES (DE)


Patent No.: US 6592989 B1 Issued: 2003-07-15

Title: Method for synthesis of hydroxyapatite, and hydroxyapatite complex and method for preparing the same

Applicant: NARA MACHINERY CO LTD (JP)

Application No.: US2000-0701181 Applic. Date: 2000-11- 27

Abstract: The present invention provides a method of synthesizing hydroxy apatite comprising the steps of preparing a mixed material slurry by dispersing calcium hydroxide (Ca(OH)2) powder into a phosphoric acid (H3PO4) solution; conducting a mechanochemical milling treatment in which shearing force and compressive force based on a centrifugal force of a mechanical rotating body are imparted to the mixed material slurry, and reacting the calcium hydrate component with the phosphoric acid component under normal temperature and pressure thereby to prepare hydroxy apatite (HAp) powder having fine crystals. According to the structure described above, there can be provided a method of synthesizing hydroxy apatite having fine and uniform particle size which can be directly synthesized under normal temperature and pressure in a short time through simple and single process.

Priority: WO1999-JP01544 Applic. Date: 1999-03-26

Inventor: SENNA MAMORU (JP); ISOBE TETSUHIKO (JP); KANAYAMA MANABU (JP)


Patent No.: US 6593744 B2 Issued: 2003-07-15
Publication No.: US20030094950A1 Published: 2003-05-22

Title: MULTI-CHANNEL RF CABLE TRAP FOR MAGNETIC RESONANCE APPARATUS

Applicant: KONINKL PHILIPS ELECTRONICS NV (NL); PHILIPS MED SYST INC (US)

Application No.: US2001-0989824 Applic. Date: 2001-11- 20

Abstract: A multi-channel RF cable trap (70) blocks stray RF current from flowing on shield conductors (114) of coaxial RF cables (60) of a magnetic resonance apparatus. An inductor (116) is formed by a curved semi-rigid trough (80) constructed of an insulating material coated with an electrically conducting layer. Preferably, the inductor (116) and the cable follow an "S"- shaped path to facilitate good electromagnetic coupling therebetween. The RF cables (60) are laid in the trough (80) and the shield conductors inductively couple with the inductor (116). A capacitor (82) and optional trim capacitor (83) are connected across the the trough of the inductor (116) to form a resonant LC circuit tuned to the resonance frequency. The LC circuit inductively couples with the shield conductors (114) to present a high, signal attenuating impedance at the resonance frequency.; The resonant circuit is preferably contained in an RF-shielding box (84) with removable lid.

Priority: US2001-0989824 Applic. Date: 2001-11-20

Inventor: BURL MICHAEL (US); CHMIELEWSKI THOMAS (US); BRAUM WILLIAM O (US)


Patent No.: US 6596264 B2 Issued: 2003-07-22
Publication No.: US20020028226A1 Published: 2002-03-07

Title: Composition especially in the form of emulsion, gel or aqueous solution, including a crosslinked poly(2-acrylamido-2- methylpropanesulphonic acid) polymer neutralized to at least 90%

Applicant: OREAL (FR); OREAL (US)

Application No.: US2001-0929263 Applic. Date: 2001-08- 15

Abstract: The invention relates to a cosmetic, dermatological, hygienic or pharmaceutical composition which is in the form of, or includes, an aqueous gel or an aqueous, hydroalcoholic or multiphase solution additionally including at least one crosslinked poly(2-acrylamido -2-methylpropanesulphonic acid) polymer neutralized to at least 90% and pigments or water-soluble dyes.

Priority: US2001-0929263 Applic. Date: 2001-08-15; FR1996-0008112 Applic. Date: 1996-06-28; US1997-0885798 Applic. Date: 1997-06-30

Inventor: TERREN NADIA (FR); FAVRE SOPHIE (FR)


Patent No.: US 6602910 B2 Issued: 2003-08-05
Publication No.: US20020045663A1 Published: 2002-04- 18

Title: D-enantiomer of DFMO and methods of use therefor

Applicant: ILEX ONCOLOGY INC (US)

Application No.: US2001-0801197 Applic. Date: 2001-03- 06

Abstract: The present invention concerns a method for preventing and/or treating cancer in a patient comprising administering an effective amount of substantially purified D enantiomer of difluoromethylornithine (D-DFMO) or an analog of D-DFMO to the patient. D-DFMO or an analog thereof is administered at a dose of about 0.05 to about 20.0 gm/M2/day. D-DFMO or an analog thereof may be administered more than once for the treatment and/or prevention of cancer. Methods of administration as well as compositions and formulations of substantially purified D-DFMO and analogs of D-DFMO are described.

Priority: US2001-0801197 Applic. Date: 2001-03-06; US2000-0187441P Applic. Date: 2000-03-07; US2000-0215866P Applic. Date: 2000-07-01

Inventor: LEVENSON COREY (US); SHAKED ZE EV (US)


Patent No.: US 6604847 B2 Issued: 2003-08-12
Publication No.: US20020085372A1 Published: 2002-07- 04

Title: Portable reading light device

Application No.: US2000-0751148 Applic. Date: 2000-12-28

Abstract: A portable reading light device utilizing an LEDs as the source of light mounted in a housing having a single lens through which light from the LEDs is projected, the power to the LEDs being controlled by Pulse Width Modulation.

Priority: US2000-0751148 Applic. Date: 2000-12-28

Inventor: LEHRER ROBERT A (US)


Patent No.: US 6616918 B2 Issued: 2003-09- 09
Publication No.: US20030044365A1 Published: 2003-03-06

Title: Self- tanning composition containing an N-acyl amino acid ester and a self-tanning agent

Applicant: OREAL (FR)

Application No.: US2002-0197252 Applic. Date: 2002-07-18

Abstract: The invention relates to cosmetic and/or dermatological compositions more particularly intended for artificially tanning and/or browning the skin, comprising, in a cosmetically acceptable support, at least one self-tanning agent and at least one N-acyl amino acid ester. The invention also relates to a cosmetic treatment process for artificially tanning and/or browning the skin, comprising applying to the skin an effective amount of the cosmetic and/or dermatological composition. The invention also relates to the use of an N-acyl amino acid ester with the aim of improving the coloration and/or stability of a self-tanning agent in a composition for artificially tanning and/or browning the skin.

Priority: FR2001-0009673 Applic. Date: 2001-07-19

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6616919 B2 Issued: 2003-09-09
Publication No.: US20030124071A1 Published: 2003-07-03

Title: Dibenzoylmethane sunscreen compositions containing photostabilizing amounts of tri-substituted butane compounds

Applicant: OREAL (FR)

Application No.: US2002-0228304 Applic. Date: 2002-08-27

Abstract: Improvedly photostable UV-photoprotecting cosmetic/dermatological compositions for the skin and/or the hair contain (a) a UV-photoprotective amount of at least one dibenzoylmethane sunscreen, e.g., 4-(tert-butyl)-4'-methoxydibenzoylmethane or 4 -isopropyldibenzoylmethane, advantageously (a') a UV-photoprotective amount of at least one 1,3,5- triazine sunscreen, e.g., 2-[(p-(tert-butylamido]-4,6-bis[(p-(2'ethylhexyl-1'-oxycarbonyl)anilino]- 1,3,5-triazine or 2,4,6-tris[p-(2'-ethylhexyl-1'-oxycarbonyl)anilino]-1,3,5-triazine, (b) an effective sunscreen photostabilizing amount of 1,1,1-tris(2-methyl-4-hydroxy-5-tert-butylphenyl)butane, formulated into (c) a topically applicable, cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: FR2001-0011139 Applic. Date: 2001-08-27

Inventor: CANDAU DIDIER (FR); AUBERT FABIEN (FR)


Patent No.: US 6620419 B1 Issued: 2003-09-16

Title: Cosmetic or dermopharmaceutical use of peptides for healing, hydrating and improving skin appearance during natural or induced ageing (heliodermia, pollution)

Applicant: SEDERMA (FR)

Application No.: US2001-0787175 Applic. Date: 2001-03-15

Abstract: The invention concerns the use of peptides of general sequence X-Thr-Thr-Lys-Y, wherein in particular X=lysine and Y=serine, in cosmetic or dermopharmaceutical compositions. It is moreover advantageous to use said peptides in mutual combination. In order to enhance their activity and their stability, the peptides are chemically modified to increase their lipophilicity, by grafting on the N-terminal amine of X, either a fatty acid chain, or by esterification or amidation of the C-terminal carboxyl group of Y. The peptides can be obtained by synthesis, biotechnology or controlled hydrolysis or plant proteins. The resulting compositions are advantageously used for stimulating healing, hydrating or all skin treatments.; They are particularly active against formation or deterioration of wrinkles and against all the consequences of skin ageing, whether natural or induced (heliodermia, pollution), as well as for dry skin.

Priority: FR1998-0011533 Applic. Date: 1998-09-15; WO1999-FR02178 Applic. Date: 1999-09-13

Inventor: LINTNER KARL (FR)


Patent No.: US 6627179 B2 Issued: 2003-09-30
Publication No.: US20030157038A1 Published: 2003-08-21

Title: SYNERGISTICALLY UV- PHOTOPROTECTING MIXED SUNSCREEN COMPOSITIONS

Applicant: OREAL (FR)

Application No.: US2002-0314182 Applic. Date: 2002-12-09

Abstract: Topically applicable cosmetic/dermatological sunscreen composition well suited for the enhanced UV-photoprotection of human skin and/or hair, contain synergistically UV-APPD-enhancing amounts of (i) at least one UV-screening silicon compound having a benzotriazole functional group substituent, (ii) at least one UV-screening dibenzoylmethane compound, and (iii) at least one UV-screening amino-substituted 2-hydroxybenzophenone compound having the following structural formula (III):formulated into (iv) a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.

Priority: FR2001-0015857 Applic. Date: 2001-12-07

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6627180 B2 Issued: 2003-09- 30
Publication No.: US20030152532A1 Published: 2003-08-14

Title: SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS

Applicant: OREAL (FR)

Application No.: US2002-0314195 Applic. Date: 2002-12-09

Abstract: Topically applicable cosmetic/dermatological sunscreen compositions well suited for the enhanced UV-photoprotection of human skin and/or hair contain synergistically UV-APPD-enhancing amounts of (a) particulates of at least one insoluble organic UV- screening agent having a particle size ranging from 10 nm to 5 mum, and (b) at least one UV-screening amino-substituted 2-hydroxybenzophenone compound having the following structural formula (I):formulated into (c) a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.

Priority: FR2001-0015860 Applic. Date: 2001-12-07

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6629990 B2 Issued: 2003-10-07
Publication No.: US20030014097A1 Published: 2003-01- 16

Title: Heat-removal method and apparatus for treatment of movement disorder episodes

Applicant: AD TECH MEDICAL INSTR CORP (US)

Application No.: US2001 -0904802 Applic. Date: 2001-07-13

Abstract: Heat-removal method and apparatus for treatment of movement disorder episodes; more specifically, a device and method for intracranially suppressing movement disorder episodes upon the detection of physiological symptoms. The device includes a temperature-contact implanted at a targeted portion in the brain which is determined to be associated with such episodes and connection to an implanted heat-transfer operator, typically a Peltier cooler or a thermal-electric cooler. Heat transfer from the temperature-contact to the heat-transfer operator cools the targeted portion and suppresses the movement disorder episode. Such heat transfer is performed upon the sensing of symptoms which normally preface episodes. The symptoms can be sensed intracranially by sensing-contacts, on the skin by a sensor or by a person or animal.; Alternatively, heat removal (cooling) can be performed without sensing symptoms to prevent episodes when the patient is particularly sensitive to, or in danger from, episodes.

Priority: US2001-0904802 Applic. Date: 2001-07 -13

Inventor: PUTZ DAVID A (US); ZIOBRO JOHN (US)


Patent No.: US 6630307 B2 Issued: 2003-10-07
Publication No.: US20010034034A1 Published: 2001-10-25

Title: Method of detecting an analyte in a sample using semiconductor nanocrystals as a detectable label

Applicant: QUANTUM DOT CORP (US)

Application No.: US2001-0887914 Applic. Date: 2001-06- 21

Abstract: The use of semiconductor nanocrystals as detectable labels in various chemical and biological applications is disclosed. The methods find use for detecting a single analyte, as well as multiple analytes by using more than one semiconductor nanocrystal as a detectable label, each of which emits at a distinct wavelength.

Priority: US2001-0887914 Applic. Date: 2001 -06-21; US2000-0566014 Applic. Date: 2000-05-05; US1999-0133084P Applic. Date: 1999-05- 07

Inventor: BRUCHEZ MARCEL P (US); DANIELS R HUGH (US); EMPEDOCLES STEPHEN A (US); PHILLIPS VINCE E (US); WONG EDITH Y (US); ZEHNDER DONALD A (US)


Patent No.: US 6632963 B1 Issued: 2003-10- 14

Title: Bicyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof

Applicant: GALDERMA RES & DEV (FR)

Application No.: US1999- 0277953 Applic. Date: 1999-03-29

Abstract: Novel pharmaceutically/cosmetically- active bicyclic aromatic compounds have the structural formula (I):in which Ar[HIL][PDAT]1 [/SB][PDAT]is a radical having one of the structural formulae (a)-(c):Ar[HIL][PDAT]2 [/SB][PDAT]is a radical having one of the following formulae (d)-(h):and X is a radical having one of the following formulae (i)- (l):and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.[/PTEXT]

Priority: FR1998-0003976 Applic. Date: 1998-03-31

Inventor: BERNARDON JEAN -MICHEL (FR)


Patent No.: US 6635239 B2 Issued: 2003-10-21
Publication No.: US20030129152A1 Published: 2003-07- 10

Title: STABLE/IMPROVEDLY SELF-TANNING COMPOSITIONS COMPRISING AMINO-SUBSTITUTED 2- HYDROXYBENZOPHENONE COMPOUNDS

Applicant: OREAL (FR)

Application No.: US2002 -0314185 Applic. Date: 2002-12-09

Abstract: Topically applicable cosmetic/dermatological self-tanning compositions well suited for enhancing the coloration imparted by and/or the stabilizing of the self-tanning agent, contain (i) an effective amount of at least one artificial/sunless tanning agent, and (ii) an effective stabilizing/enhancedly self-tanning amount of at least one amino-substituted 2-hydroxybenzophenone compound having the following structural formula (I):formulated into (iii) a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.

Priority: FR2001-0015856 Applic. Date: 2001-12- 07

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6638918 B2 Issued: 2003-10-28
Publication No.: US20030104020A1 Published: 2003-06-05

Title: Chitosan compositions

Applicant: PROCTER & GAMBLE (US)

Application No.: US2002- 0280617 Applic. Date: 2002-10-25

Abstract: Compositions comprising chitosan in the form of a network of nano-sized fibres. There is also provided a process for making such compositions. The compositions have improved solubility and activity. The compositions are useful in hair care, skin care, odour control, wound care, blood management, sanitary compositions, oral care, film formation, hard surface treatment, fabric treatment, release of hydrophobic or hydrophilic materials, plant care, water purification and drug delivery.

Priority: GB2001-0026923 Applic. Date: 2001-11- 09

Inventor: DAVISON GORDON ROBERT (GB); KONIG AXEL (BE); GIBBONS CLYDE (GB); RIPLEY MARK BRIAN (GB); MACGILP NEIL ARCHIBALD (GB); MILICH GEORGINA LYNDSEY CLAIRE (GB); PRETSWELL EMMA LOUISE (GB)


Patent No.: US 6641802 B2 Issued: 2003-11-04
Publication No.: US20020150545A1 Published: 2002-10- 17

Title: Amino acid compounds and photoprotecting compositions comprised thereof

Applicant: OREAL (FR)

Application No.: US2001-0026607 Applic. Date: 2001-12-27

Abstract: Amino acid compounds having the formula (I):are well suited for the UV-photoprotection of human skin and/or hair, as well as for the UV-photoprotection of a wide variety of photosensitive industrial materials/substrates, e.g., plastics, glasses, textiles, etc.

Priority: FR2000-0005393 Applic. Date: 2000-04-27; WO2001-FR01137 Applic. Date: 2001-04-12

Inventor: BORDIER THIERRY (FR); PHILIPPE MICHEL (FR)


Patent No.: US 6650302 B2 Issued: 2003-11- 18
Publication No.: US20030011525A1 Published: 2003-01-16

Title: Ultra- wideband monopole large-current radiator

Applicant: AETHER WIRE & LOCATION (US); AETHER WIRE & LOCATION INC (US)

Application No.: US2002-0186799 Applic. Date: 2002-07-01

Abstract: An ultra-wideband, large-current radiator consisting of a ground plane and two electric monopoles: a wide radiating monopole orthogonal to the ground plane, and a thin monopole orthogonal to the ground plane and normally displaced from the wide monopole. The frequency- independent low impedance of the antenna allows a small voltage to generate a large current. The wide radiating monopole may be a flat sheet, or a sheet of parallel bars. Shielding by the wide monopole suppresses radiation from the thin monopole into a sector of space into which the monopole radiation characteristic of a well-formed impulse in response to a voltage step is desired. In one preferred embodiment, two parallel flat sheets or a conducting cylinder is used as the wide radiating monopole, further shielding radiation from the thin monopole.

Priority: US2002-0186799 Applic. Date: 2002-07-01; US2001-0305398P Applic. Date: 2001-07-13

Inventor: SANAD MOHAMED SAID (US)


Patent No.: US 6657717 B2 Issued: 2003-12-02
Publication No.: US20020118361A1 Published: 2002-08- 29

Title: Device for verifying the accuracy of a spectral analyzer

Applicant: CME TELEMETRIX INC (CA)

Application No.: US2002-0085983 Applic. Date: 2002-02-28

Abstract: The present invention provides an artificial member (80, 210) which mimics the absorbance spectrum of a body part and includes the spectral components of blood analytes. The artificial member comprises a light scattering and reflecting material, and has a chamber portion comprising one or more chambers (90, 100, 220). The artificial member is configured to be reproducibly received in a measuring receptor which receptor is operatively connected to a non-invasive monitoring device.

Priority: US2002-0085983 Applic. Date: 2002-02-28; WO2000-CA01006 Applic. Date: 2000-08-31; US1999-0151681P Applic. Date: 1999-08- 31

Inventor: CADELL THEODORE E (CA); DRENNAN PAUL (CA); SAMSOONDAR JAMES (CA); PAWLUCZYK ROMUALD (CA); KAUSHAL ASHWANI (CA); BEDNARZ BRONISLAW (CA); KUTA JOHN (CA)


Patent No.: US 6660285 B2 Issued: 2003-12- 09
Publication No.: US20030086953A1 Published: 2003-05-08

Title: Use of amphoteric surfactants in cosmetic compositions to precipitate cationic polymers on dilution

Application No.: US2002-0188896 Applic. Date: 2002-07- 05

Abstract: The invention relates to the use of at least one amphoteric in transparent aqueous cosmetic compositions for the hair and/or the skin designed to be rinsed, comprising at least one anionic surface-active agent, at least one surface-active agent selected for the betaines and at least one water-soluble or water dispersible cationic polymer derived from a polysaccharide (PolC), as precipitant, in the diluted state, of said cationic polymer (PolC). The invention further relates to transparent aqueous cosmetic compositions for the hair and/or skin designed to be rinsed, comprising at least one one anionic surface-active agent, at least one surface-active agent selected for the betaines, at least one water-soluble or water dispersible cationic polymer derived from a polysaccharide (PolC), and at least one amphoteric surface-active agent.

Priority: US2002-0188896 Applic. Date: 2002-07-05; FR1998-0000634 Applic. Date: 1998-01-19; US2000-0600371 Applic. Date: 2000-07- 14

Inventor: RICCA JEAN-MARC (FR)


Patent No.: US 6669627 B1 Issued: 2003-12- 30

Title: REM sleep augmentation with extra-ocular light

Applicant: CORNELL RES FOUNDATION INC (US)

Application No.: US2001-0937324 Applic. Date: 2001-09- 20

Abstract: The invention provides for exposing an extraocular (i.e., non-ocular) region of a human to light during sleep which enhances REM sleep. Also provided are devices to carry out the methods. Key timing parameters ensure effective REM enhancement without adversely impacting a subject's circadian clock. The invention provides for improving cognitive function and performance in healthy individuals, and in individuals suffering from a disease or disorder in which mental status is compromised. One embodiment of the invention (100) includes a fiber optics pad (160) attached to a power source, and lamp housing (120) by a fiber optics cable (140).

Priority: US2001-0937324 Applic. Date: 2001-09-20; US1999-0143217P Applic. Date: 1999-07-09; WO2000-US18820 Applic. Date: 2000 -07-07

Inventor: CAMPBELL SCOTT S (US); MURPHY PATRICIA J (US)


Patent No.: US 6673096 B2 Issued: 2004-01- 06
Publication No.: US20020111656A1 Published: 2002-08-15

Title: System and method for tissue treatment

Applicant: BIOCELLULASE INC (US)

Application No.: US2001-0000459 Applic. Date: 2001-11-02

Abstract: A system and method for the treatment of body tissue is provided that includes a radiation-emitting device and a massaging mechanism. In accordance with one embodiment, the radiation-emitting device is a laser and the massaging mechanism is an automated mechanical massaging mechanism. The radiation-emitting device can emit radiation in the visible and infrared wavelengths. The radiation-emitting device can emit radiation in a concentric combination of infrared and visible laser light. The method of using the tissue treatment system includes exposing a skin surface of a patient to radiation emitted from the radiation-emitting device at predetermined wavelengths for predetermined periods of time. The method further provides for massaging the exposed skin surface of the patient with the massaging mechanism. The tissue treatment system can be utilized to effect the reduction of excess cellulite.

Priority: US2001- 0000459 Applic. Date: 2001-11-02; US2000-0245948P Applic. Date: 2000-11-03

Inventor: LACH ELLIOT (US)


Patent No.: US 6676883 B2 Issued: 2004-01-13
Publication No.: US20030001315A1 Published: 2003-01- 02

Title: Methods for preparing coated polyester articles

Applicant: ADVANCED PLASTICS TECHNOLOGIES (US)

Application No.: US2002-0152318 Applic. Date: 2002-05-20

Abstract: This invention relates to articles made of polyester, preferably polyethylene terephthalate (PET), having coated directly to at least one of the surfaces thereof one or more layers of thermoplastic material with good gas-barrier characteristics, and novel methods of making such articles. Preferably the barrier-coated articles take the form of preforms coated by at least one layer of barrier material and the containers blow-molded therefrom. Such barrier-coated containers are preferably of the type to hold beverages such as soft drinks, beer or juice. The preferred barrier materials have a lower permeability to oxygen and carbon dioxide than PET as well as key physical properties similar to PET. The materials and methods provide that the barrier layers have good adherence to PET, even during and after the blow molding process to form containers from preforms.; Preferred barrier coating materials include poly(hydroxyamino ethers). In one preferred method, preforms are injection molded then barrier-coated immediately thereafter.

Priority: US2002-0152318 Applic. Date: 2002-05-20; US1998-0174971 Applic. Date: 1998-10-19; US1997-0953595 Applic. Date: 1997- 10-17; US1998-0078641P Applic. Date: 1998-03-19

Inventor: HUTCHINSON GERALD A (US); LEE ROBERT A (GB)


Patent No.: US 6682244 B2 Issued: 2004-01-27
Publication No.: US20020021932A1 Published: 2002-02- 21

Title: Devices and methods for dispensing

Applicant: OREAL (FR)

Application No.: US2001-0859444 Applic. Date: 2001-05-18

Abstract: A device for dispensing comprises a reservoir containing a composition comprising particles containing at least one fluid, an application member having at least a portion removably disposed within the reservoir and configured to be loaded with the composition and a compacting member configured to exert pressure on at least the portion of the application member during removal of the portion of the application member from the reservoir.

Priority: FR2000-0006449 Applic. Date: 2000-05- 19

Inventor: GUERET JEAN-LOUIS H (FR); GUERET JEAN LOUIS H (FR)


Patent No.: US 6685927 B2 Issued: 2004-02- 03
Publication No.: US20030059386A1 Published: 2003-03-27

Title: Topical application of chromophores for hair removal

Applicant: CERAMOPTEC IND INC (US)

Application No.: US2001-0965354 Applic. Date: 2001-09-27

Abstract: A device and method is disclosed for permanent or semi-permanent removal of hair through the activation of microparticles introduced into hair follicles. Microparticles are incorporated into a composition that is topically applied to the skin. These microparticles containing or consisting of chromophores or chemically activated molecules are of a variety of shapes and sizes. Microparticles are within a size range of 1 micron to 70 microns, and preferably between 10 and 50 microns. Microparticles of this size and variety of shapes enter hair follicles on all areas of the skin without entering other areas of the skin, such as the stratum corneum or sweat gland channels.; Treatment of the skin with electromagnetic radiation, ultrasonic radiation or chemical means activates the chromophore or chemically activated compounds, thus destroying the hair follicle without damaging other areas of the skin. In another embodiment, microparticles further contain nanoparticles released further into the hair follicle by use of a solvent or other method, allowing chromophores or chemically activated molecules to penetrate deeper into the follicle and avoid structures such as the sebaceous gland.

Priority: US2001-0965354 Applic. Date: 2001-09-27

Inventor: SUMIAN CHRYSLAIN (DE); NEUBERGER WOLFGANG (MY); MORDON SERGE (FR)


Patent No.: US 6689349 B1 Issued: 2004-02-10

Title: Skin protection agents containing a fragment mixture produced from hyaluronic acid by hydrolysis

Applicant: ESPARMA GMBH (DE)

Application No.: US2001-0868955 Applic. Date: 2001-09- 10

Abstract: The invention relates to an agent for the treatment, prophylaxis and metaphylaxis of functional and structural disorders of the skin caused by external factors. The agent contains a hyaluronic acid partially digested with a microbiological hyaluronate lyase. The hyaluronic acid fragment mixture is incorporated in different galenic formulations to which other hydrophilic and/or lipophilic active substances and/or auxiliary substances can be added. Fields of application of the invention in human and veterinary medicine relate to the treatment and/or the prophylaxis of skin damage caused by environmental factors including UV, dry skin conditions and skin ageing.

Priority: DE1998-1060544 Applic. Date: 1998-12-23; WO1999-EP10336 Applic. Date: 1999-12-22

Inventor: WOHLRAB WOLFGANG (DE); NEUBERT REINHARD (DE); HUSCHKA CHRISTOPH (DE); MUELLER PETER-JUERGEN (DE); OZEGOWSKI JOERG-HERMAN (DE); KOEGST DIETER (DE); FRIES GERHARD (DE)


Patent No.: US 6689371 B1 Issued: 2004-02-10

Title: Nanoemulsion based on sugar fatty esters or on sugar fatty ethers and its uses in the cosmetics, dermatological and/or ophthalmological fields

Applicant: OREAL (FR)

Application No.: US1999-0460092 Applic. Date: 1999-12-13

Abstract: A nanoemulsion, the oily globules of which have a number- average size of less than 100 nm, comprising a surfactant which is solid at a temperature of less than or equal to 45 DEG C., which surfactant is chosen from esters of a fatty acid and of a sugar and ethers of a fatty alcohol and of a sugar, and at least one oil having a molecular weight of greater than 400, the ratio by weight of the amount of oily phase to the amount of surfactant ranging from 2 to 10. The nanoemulsion may be used for cosmetics and dermatological applications, in particular for moisturizing the skin and/or mucous membranes, as well as for treating the hair, and in the ophthalmological field, as an eye lotion for treating the eyes.

Priority: FR1998-0015765 Applic. Date: 1998-12- 14

Inventor: SIMONNET JEAN-THIERRY (FR); SONNEVILLE ODILE (FR); LEGRET SYLVIE (FR)


Patent No.: US 6690959 B2 Issued: 2004-02-10
Publication No.: US20020028991A1 Published: 2002-03- 07

Title: Skin-mounted electrodes with nano spikes

Applicant: MEDTRONIC INC (US)

Application No.: US2001-0944821 Applic. Date: 2001-08- 31

Abstract: Epidermally mountable device includes terminus structures to enable positive connection with conductive tissue. The device includes nano spikes shaped to penetrate the epidermis of the skin to collect electrical biopotentials such as cardiac depolarization waveforms (ECGs) and various signals transmitted by implanted devices. Generally, the nano spikes are integrated on a substrate comprising, preferably, a flexible metalized conductive plate attachable to an adhesive backing. The device could be mounted on any external body of the patient to collect ECG, EEG or other signals. Further, the device is adaptable to include a programmable microprocessor, including memory and an antenna to store, receive and transmit data as needed.; In one embodiment, in addition to collecting physiologic data through direct contact, the device may also be used as a smart patch to download, store and transfer data from implanted medical devices or other data sources using wireless data transmission medium.

Priority: US2001-0944821 Applic. Date: 2001-08-31; US2000-0229925P Applic. Date: 2000-09-01

Inventor: THOMPSON DAVID L (US)


Patent No.: US 6692773 B2 Issued: 2004-02-17
Publication No.: US20020051824A1 Published: 2002-05-02

Title: Treatment of hyperproliferative skin disorders and diseases

Applicant: NUCRYST PHARM CORP (CA)

Application No.: US2001-0916757 Applic. Date: 2001-07-27

Abstract: The invention relates to the use of one or more noble metals selected from silver, gold, platinum, and palladium but most preferably silver, in a nanocrystalline form, for the treatment of a hyperproliferative skin disorder or disease such as psoriasis. Among the noble metals, silver is preferred for such treatment. The nanocrystalline noble metal of choice may be used in the form of a nanocrystalline coating of one or more noble metals, a nanocrystalline powder of one or more noble metals, or a solution containing dissolved species from a nanocrystalline powder or coating of one or more noble metals.

Priority: US2001-0916757 Applic. Date: 2001-07-27; US2000-0628735 Applic. Date: 2000-07-27

Inventor: BURRELL ROBERT EDWARD (CA); WRIGHT JOHN BARRYMORE (CA); LAM KAN (CA)


Patent No.: US 6698880 B1 Issued: 2004-03-02

Title: Porous inkjet recording system comprising ink- pigment-trapping surface layer

Applicant: EASTMAN KODAK CO (US)

Application No.: US2002-0251936 Applic. Date: 2002-09-20

Abstract: An inkjet recording system comprising a pigment-based ink in combination with a recording element having a porous substrate with relatively large pores and a relatively thin overlying surface layer which traps pigment particles, from an applied pigmented ink, at or near the surface while not unduly restricting ink flow into the underlying porous substrate.

Priority: US2002-0251936 Applic. Date: 2002-09- 20

Inventor: CAMPBELL BRUCE C (US); RECZEK JAMES A (US); TODD LISA B (US)


Patent No.: US 6699460 B2 Issued: 2004-03-02
Publication No.: US20030180230A1 Published: 2003-09-25

Title: UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds

Applicant: OREAL (FR)

Application No.: US2002-0314184 Applic. Date: 2002-12-09

Abstract: Topically applicable cosmetic/dermatological sunscreen compositions well suited for the stable UV-photoprotection of human skin and/or hair, are devoid of any p-methylbenzylidenecamphor, but which contain (a) an effective photoprotecting amount of at least one UV-sunscreening dibenzoylmethane compound, (b) an effective photoprotecting amount of at least one UV- screening 1,3,5-triazine compound normally photosensitive in the presence of a dibenzoylmethane compound (a), and (c) an effective photostabilizing amount of at least one UV-screening amino-substituted 2- hydrozybenzophenone compound having the following structural formula (VIII):formulated into (d) a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.

Priority: FR2001-0015859 Applic. Date: 2001-12-07

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6699461 B2 Issued: 2004-03-02
Publication No.: US20030161793A1 Published: 2003-08- 28

Title: UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds

Applicant: OREAL (FR)

Application No.: US2002-0314186 Applic. Date: 2002-12-09

Abstract: Topically applicable cosmetic/dermatological sunscreen compositions well suited for the stable UV-photoprotection of human skin and/or hair are devoid of any p-methylbenzylidenecamphor, but contain (a) an effective photoprotecting amount of at least one UV-screening dibenzoylmethane compound, and (b) an effective photostabilizing amount of at least on UV-screening amino-substituted 2-hydroxybenzophenone compound having the following structural formula (I):formulated into (c) a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.

Priority: FR2001-0015858 Applic. Date: 2001-12-07

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6699462 B2 Issued: 2004-03- 02
Publication No.: US20030138387A1 Published: 2003-07-24

Title: Artificial tanning compositions comprising sorghum extracts

Applicant: OREAL (FR)

Application No.: US2003-0338700 Applic. Date: 2003-01-09

Abstract: Topically applicable, cosmetic/dermatological artificial tanning compositions devoid of certain flavylium salts contain an effective artificial tanning amount of at least one sorghum extract formulated into a topically applicable, cosmetically/dermatologically acceptable vehicle therefor.

Priority: FR2002-0000251 Applic. Date: 2002-01-10; FR2002-0000252 Applic. Date: 2002-01-10; FR2002-0000253 Applic. Date: 2002-01-10

Inventor: SEYLER NATHALIE (FR); ELGUIDJ IRENE (FR); CANDAU DIDIER (FR)


Patent No.: US 6702838 B1 Issued: 2004-03- 09

Title: Method of treating hypotrophic scars enlarged pores

Applicant: LUMENIS INC (US)

Application No.: US2000-0663987 Applic. Date: 2000-09- 18

Abstract: Skin including hypotrophic scars is irradiated with laser radiation having a wavelength between about 525 and 550 nanometers. The irradiation is delivered at a fluence that stimulates wound healing responses without actually inflicting a wound. The wound healing properties promote growth of dermal extracellular matrix. Absorption properties of hemoglobin and melanin in the 525 to 550 nanometer wavelength range provide that wound healing response is concentrated close to upper regions of the skin and accordingly close to the location of the scars. The growth of dermal extracellular matrix "bulks-up" irradiated dermal tissue. This makes the depressions of hypertrophic scars shallower and less apparent. The method has also been observed to cause shrinkage of enlarged pores.

Priority: US2000-0663987 Applic. Date: 2000-09-18

Inventor: ANDERSEN DAN E (US); BERNSTEIN ERIC F (US)


Patent No.: US 6703002 B2 Issued: 2004-03-09
Publication No.: US20030161794A1 Published: 2003-08-28

Title: Synergistically UV- photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds

Applicant: OREAL (FR)

Application No.: US2002-0314188 Applic. Date: 2002-12-09

Abstract: Topically applicable cosmetic/dermatological sunscreen compositions well suited for the enhanced UV-photoprotection of human skin and/or hair, contain synergistically SPF-enhancing amounts of (a) benzene-1,4-di(3-methylidene-10-camphorsulfonic acid), optionally in partially or completely neutralized state, and (b) at least one amino-substituted 2- hydroxybenzophenone compound having the following structural formula (I):formulated into (c) a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.

Priority: FR2001-0015861 Applic. Date: 2001-12-07

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6703536 B2 Issued: 2004-03-09
Publication No.: US20030139711A1 Published: 2003-07- 24

Title: Disposable absorbent article having a skin care composition containing an enzyme inhibitor

Applicant: PROCTER & GAMBLE (US)

Application No.: US2002- 0323386 Applic. Date: 2002-12-18

Abstract: An absorbent article, at least a portion of which comprises a skin care composition that comprises an enzyme inhibitor and is at least partially transferred from the article to the skin of a wearer of the article as a result of normal contact, wearer motion and/or body heat. The enzyme inhibitor is transferred to the skin with the skin care composition and is available at the skin/urine and skin/feces interfaces to inhibit enzymatic activity on the skin and to reduce or prevent the occurrence of inflammation. Repeated application of similar treated articles to the wearer's skin provides an available source with which the enzyme inhibitor transfers onto the skin continuously over time and accumulates to provide a proactive defense against harmful enzymes for the treatment and/or prevention of diaper dermatitis.

Priority: US2002-0323386 Applic. Date: 2002-12-18; WO1999-US05311 Applic. Date: 1999-03-11; US2000-0623813 Applic. Date: 2000-09-08; US1998-0041266 Applic. Date: 1998-03-12

Inventor: ROE DONALD CARROLL (US); ROURKE FRANCIS JAMES (US); OSBORNE SCOTT EDWARD (US)


Patent No.: US 6710066 B2 Issued: 2004-03-23
Publication No.: US20010021370A1 Published: 2001-09-13

Title: Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins

Applicant: UNIV KINGSTON (CA)

Application No.: US2001-0816329 Applic. Date: 2001-03- 26

Abstract: Methods of detecting and treating rapidly growing exogenous cells, such as Protista, or parasites, that preferentially accumulate a photoactivatable porphyrin in which 5- aminolevulinic acid or precursor thereof is administered to the patient, or contacted to the exogenous cells, in an amount sufficient to induce synthesis fluorescence and/or photosensitizing concentrations of a protoporphyrin IX in the exogenous cells, followed by exposure of the exogenous cells to light of photoactivating wavelengths.

Priority: US2001-0816329 Applic. Date: 2001-03-26; US1999- 0293835 Applic. Date: 1999-04-19; US1993-0082113 Applic. Date: 1993-06-28; US1992-0865151 Applic. Date: 1992-04-08; US1991-0783750 Applic. Date: 1991-10-28; US1989-0386414 Applic. Date: 1989-07- 28

Inventor: KENNEDY JAMES C (CA); POTTIER ROY H (CA); POTTIER ROY H (US); REID ROBERT L (CA); SAC-MORALES ARNOLD (CA); TOMALTY LEWIS L (CA)


Patent No.: US 6719986 B1 Issued: 2004-04- 13

Title: Hyaluronate lyase used for promoting penetration in topical agents

Applicant: ESPARMA GMBH (DE)

Application No.: US2001-0869087 Applic. Date: 2001-09-05

Abstract: The invention relates to an agent for treating skin diseases and/or functional disorders of the skin on the basis of different medicaments and/or auxiliary substances through promotion of penetration from topical formulations into the skin. According to the invention, the agent is composed of a hyaluronate lyase produced by microbial means and a medicament, preferably a hydrophilic medicament and/or auxiliary substances in different galenic formulations including colloidal carrier systems. The areas of application for the invention in human and veterinary medicament relate to the treatment, prophylaxis and/or metaphylaxis of skin diseases, functional disorders of the skin, the processes of skin ageing and dry skin conditions.

Priority: DE1998-1060545 Applic. Date: 1998-12-23; WO1999-EP10337 Applic. Date: 1999-12-22

Inventor: WOHLRAB WOLFGANG (DE); NEUBERT REINHARD (DE); HUSCHKA CHRISTOPH (DE); MUELLER PETER-JUERGEN (DE); OZEGOWSKI JOERG-HERMAN (DE); KOEGST DIETER (DE); FRIES GERHARD (DE)


Patent No.: US 6720006 B2 Issued: 2004-04-13
Publication No.: US20020122832A1 Published: 2002-09- 05

Title: Anti-microbial body care product

Application No.: US2001-0017996 Applic. Date: 2001-12-14

Abstract: An anti-microbial body care product comprising in the part contacting the human or animal skin and/or mucosa and organic matrix containing homogeneously dispersed particles of a metallic silver having a particle size in the range of 1 to 50 nm (silver nanoparticles) in an amount providing on the surface of said part and anti-microbially effective but less than cytotoxic silver concentration. Preferred body care products are disposable absorbent articles, toothbrushes, cosmetic products and baby comforting products.

Priority: US2001- 0017996 Applic. Date: 2001-12-14; EP1999-0111729 Applic. Date: 1999-06-17; WO2000-US15897 Applic. Date: 2000-06-09

Inventor: HANKE BERNHARD (DE); GUGGENBICHLER PETER J (DE)


Patent No.: US 6733614 B2 Issued: 2004-05-11
Publication No.: US20030143412A1 Published: 2003-07-31

Title: Process for forming thermal conductive sheet

Applicant: KITAGAWA IND CO LTD (JP)

Application No.: US2003-0358425 Applic. Date: 2003-02-04

Abstract: A thermal conductive sheet with conductive foil is obtained by press bonding a magnetic foil to a thermal conductive layer via a primer layer. Since the primer layer contains a thermal conductive filler, it has high thermal conductivity and does not interrupt thermal conduction from the thermal conductive layer to the magnetic foil. It also spontaneously destroys a skin layer on the surface of the thermal conductive layer upon the press bonding. Accordingly, the thermal conductive sheet with conductive foil of the present invention improves thermal conduction from the thermal conductive layer to the conductive foil, eliminating the unfavorable effects of the skin layer and the primer layer, and thus improves heat radiation of the thermal conductive sheet with conductive foil.

Priority: US2003-0358425 Applic. Date: 2003-02-04; JP2000-0242788 Applic. Date: 2000-08-10; US2001-0923509 Applic. Date: 2001- 08-06

Inventor: YAMAGUCHI AKIO (JP); KAWAI HIDEHARU (JP); KAWAGUCHI YASUHIRO (JP)


Patent No.: US 6740313 B2 Issued: 2004-05-25
Publication No.: US20030133887A1 Published: 2003-07-17

Title: Compositions for giving the skin a coloration similar to that of a natural tan, based on a pigment of the monascus type, and uses thereof

Applicant: OREAL (FR)

Application No.: US2002-0270530 Applic. Date: 2002-10-16

Abstract: A cosmetic and/or dermatological composition that produces on the skin a long-lasting and non-covering coloration similar to that of a natural tan comprising, in a cosmetically acceptable medium, at least one pigment, which may be obtained by extraction with an organic or aqueous-organic solvent of a culture medium of micromycetes of the Monascus type, as well as the use of the composition for giving the skin a long-lasting and non-covering coloration similar to that of naturally tanned skin.

Priority: FR2001-0013334 Applic. Date: 2001-10-16; FR2001-0013335 Applic. Date: 2001-10-16; FR2001-0013336 Applic. Date: 2001-10- 16

Inventor: FORESTIER SERGE (FR); CANDAU DIDIER (FR); SEYLER NATHALIE (FR); ELGUIDJ IRENE (FR)


Patent No.: US 6746444 B2 Issued: 2004-06-08
Publication No.: US20020095143A1 Published: 2002-07- 18

Title: Method of amplifying a beneficial selective skin response to light energy

Application No.: US2001-0024270 Applic. Date: 2001-12- 17

Abstract: A method of altering the appearance of a region of skin is disclosed. The method includes applying a sensitizing wavelength of light the region, and applying a treatment wavelength of light to the skin, wherein the treatment wavelength is a shorter wavelength than the sensitizing wavelength. The application of the sensitizing wavelength of light and the treatment wavelength of light results in a change in a physical property of the skin.

Priority: US2001-0024270 Applic. Date: 2001-12-17; US2000-0256555P Applic. Date: 2000-12-18; US2000-0258006P Applic. Date: 2000-12-20

Inventor: KEY DOUGLAS J (US)


Patent No.: US 6749839 B2 Issued: 2004-06-15
Publication No.: US20030031691A1 Published: 2003-02-13

Title: Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile

Applicant: OREAL (FR)

Application No.: US2002-0174485 Applic. Date: 2002-06- 19

Abstract: Cosmetic compositions for topical use for protecting the skin and the hair, containing, in a cosmetically acceptable support, at least one compound of formula (1) or (2)in which X1 represents R3-(C=O)-, R3-SO2- or R3-O-(C=O)-, X2 represents -(C=O)-R'3-(C=O)-, -SO2-R'3-SO2- or -(C=O)- O-R'3-O-(C=O)-, Y represents -(C=O)-R4 or -SO2R5,R2 represents a C1-8 alkyl group, n is 0, 1 or 2, R3 represents C1-30 alkyl or C3-30 alkenyl, R'3 represents a single bond or a divalent C1-30 alkylene or C3-30 alkenylene radical, R4 represents -OR6 or -NHR6, R5 represents C1-30 alkyl or a phenyl nucleus, R6 represents C1-30 alkyl or C3-30 alkenyl, and novel compounds of formula (2).

Priority: FR2001-0008092 Applic. Date: 2001-06-20

Inventor: RICHARD HERVE (FR); LUPPI BERNADETTE (FR)


Patent No.: US 6776980 B1 Issued: 2004-08-17

Title: Photoprotective/cosmetic compositions comprising dibenzoylmethane/triazine/diphenylacrylate compounds

Applicant: OREAL (FR)

Application No.: US1998-0099939 Applic. Date: 1998-06-19

Abstract: Improvedly photostable, topically applicable cosmetic/dermatological sunscreen compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) 4-tert-butyl-4'-methoxydibenzoylmethane, (ii) at least one particular 1,3,5-triazine compound, and (iii) at least one alkyl alpha-cyano-beta,beta'- diphenylacrylate, formulated in a cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.

Priority: US1998-0099939 Applic. Date: 1998-06-19; FR1996-0008172 Applic. Date: 1996-07-01; US1997-0886245 Applic. Date: 1997-07-01

Inventor: ALLARD DELPHINE (FR); FORESTIER SERGE (FR)


Patent No.: US 6780430 B2 Issued: 2004-08-24
Publication No.: US20030078238A1 Published: 2003-04-24

Title: Stabilzation method of nano-sized emulsion using tocopheryl derivatives and external application for skin containing the same

Applicant: PACIFIC CORP (KR)

Application No.: US2002-0120389 Applic. Date: 2002-04-12

Abstract: Disclosed herein is a stabilization method of nano-sized emulsion by using lecithin and tocopheryl derivatives represented by the following formula (I) and(Wherein,R1, R2 and R3 are H or methyl group, and at least one position selected from the group consisting of the R1, R2 and R3 positions are methyl group; and,A is CH2-CH(CH3)- or CH=C(CH3)-)and an external application for skin containing the stabilized nano-sized emulsion.

Priority: KR2001-0031360 Applic. Date: 2001-06- 05

Inventor: YOO BYUNG HEE (KR); KIM JOUNG SOO (KR); KANG BYUNG YOUNG (KR); KIM KIL JOONG (KR); HAN SANG HOON (KR); KIM JOONG SOO (KR)


Patent No.: US 6780888 B1 Issued: 2004-08- 24

Title: Silicon compounds derived from ascorbic acid

Applicant: OREAL (FR)

Application No.: US2002-0111537 Applic. Date: 2002-05- 24

Abstract: The invention concerns novel silicon compounds derived from ascorbic acid consisting of a silicon-containing chain or of silanes, comprising at least a radical A of formula (I) wherein: at least one of the radicals L is a divalent radical for fixing A on the silicon chain. The invention further concerns methods for preparing said compounds, compositions, in particular cosmetic or pharmaceutical, containing them, and their use as antioxidant and/or anti-free radical agent, particularly for treating oxidant stress, for treating the effects of exposure to the sun and for preventing ageing.

Priority: FR1999-0013355 Applic. Date: 1999-10-26; WO2000-FR02713 Applic. Date: 2000-09-29

Inventor: XU JINZHU (FR); RICHARD HERVE (FR)


Patent No.: US 6781690 B2 Issued: 2004-08- 24
Publication No.: US20020015150A1 Published: 2002-02-07

Title: Sensors employing nanoparticles and microcavities

Applicant: UNIV NEW MEXICO STATE TECH TRA (US)

Application No.: US2001-0797609 Applic. Date: 2001-03-01

Abstract: An optical sensing enhancing material (and corresponding method of making) comprising: a medium, the medium comprising a plurality of aggregated nanoparticles comprising fractals; and a microcavity, wherein the medium is located in a vicinity of the microcavity. Also an optical sensor and sensing method comprising: providing a doped medium, the medium comprising a plurality of aggregated nanoparticles comprising fractals, with the material; locating the doped medium in the vicinity of a microcavity; exciting the doped medium with a light source; and detecting light reflected from the doped medium.

Priority: US2001-0797609 Applic. Date: 2001-03-01; US2000-0572721 Applic. Date: 2000-05-16; US1999-0134564P Applic. Date: 1999-05-17; US2000-0190863P Applic. Date: 2000-03- 20

Inventor: ARMSTRONG ROBERT L (US); SHALAEV VLADIMIR M (US); SMITH HAROLD V (US)


Patent No.: US 6783502 B2 Issued: 2004-08-31
Publication No.: US20020177761A1 Published: 2002-11- 28

Title: Integrated lancing and analytic device

Applicant: PHOENIX BIOSCIENCE (US)

Application No.: US2002-0131973 Applic. Date: 2002-04- 24

Abstract: This invention provides for an integrated device having a lance and analytic device in a single disposable unit where the lance releases fluid from skin and the analytic device collects and analyzes the fluid without the user removing an instrument housing which holds the disposable unit. In addition to the device, this invention provides for methods of using and manufacturing the device.

Priority: US2002-0131973 Applic. Date: 2002-04-24; US2001- 0286822P Applic. Date: 2001-04-26; WO2002-US30129 Applic. Date: 2002-09-20

Inventor: ORLOFF EUGENE L Y (US); SUBRAMANIAN KUMAR (US)


Patent No.: US 6806089 B1 Issued: 2004-10- 19

Title: Low frequency modulation sensors using nanosecond fluorophores

Applicant: UNIV MARYLAND (US)

Application No.: US2001-0786627 Applic. Date: 2001-04-17

Abstract: Described is a new approach to fluorescence sensing based on a mixture of fluorophores, one of which is sensitive to the desired analyte. If a long lifetime analyte-insensitive fluorophore is mixed with a short lifetime analyte-sensitive fluorophore, the modulation of the emission at conveniently low frequencies becomes equal to the fractional fluorescence intensity of the sensing fluorophore. Under these conditions the modulation can be used to determine the analyte concentration. This can be used with any fluorophore which changes intensity in response to analyte, and does not require the sensing fluorophore to display a change in lifetime. The feasibility of modulation-based sensing was demonstrated using mixtures of 6-carboxyfluorescein and [Ru2,2'(bipyridyl)3][2+] as a pH sensor and of the calcium probe Fluo-3 and [Ru2,2'(bipyridyl)3][2+] as a calcium sensor.

Priority: US2001-0786627 Applic. Date: 2001-04-17; US1998-0099499P Applic. Date: 1998-09-08; WO1999-US20370 Applic. Date: 1999-09-08

Inventor: LAKOWICZ JOSEPH R (US); GRYCZYNSKI IGNACY (US)


Patent No.: US 6808532 B2 Issued: 2004-10-26
Publication No.: US20020077678A1 Published: 2002-06-20

Title: Laser treatment for reducing wrinkles

Application No.: US2000-0738523 Applic. Date: 2000-12- 15

Abstract: Skin including wrinkles is irradiated with laser radiation having a wavelength between about 525 and 550 nanometers. The irradiation is delivered at a fluence that stimulates wound healing responses without actually inflicting a wound. This promotes deposition of dermal extracellular matrix. Absorption properties of hemoglobin and melanin in the 525 to 550 nanometer wavelength range provide that wound healing response is concentrated close to upper regions of the skin and accordingly close to the location of the wrinkles. The growth of dermal extracellular matrix "bulks-up" irradiated dermal tissue. This makes the depressions or folds of the wrinkles shallower and less apparent.

Priority: US2000-0738523 Applic. Date: 2000-12- 15

Inventor: ANDERSEN DAN E (US); BERNSTEIN ERIC F (US)


Patent No.: US 6808785 B1 Issued: 2004-10- 26

Title: Synthetic roofing shingle or tile

Applicant: CERTAIN TEED CORP (US)

Application No.: US2003-0452060 Applic. Date: 2003-06- 02

Abstract: A synthetic roofing shingle or tile is provided, in which a core material is formed, of generally less expensive material, and with a skin material provided, disposed thereabout, with the skin material being generally of greater expense and having desirable weather-withstanding qualities.

Priority: US2003-0452060 Applic. Date: 2003-06-02

Inventor: FRIEDMAN MICHAEL L (US); KALKANOGLU HUSNU M (US); KIM JOONG YOUN (US); MACKINNON THOMAS KEVIN (US)


Patent No.: US 6811563 B2 Issued: 2004-11-02
Publication No.: US20040138726A1 Published: 2004-07- 15

Title: Portable light delivery apparatus and methods for delivering light to the human body

Applicant: SAVAGE JR HENRY C (US)

Application No.: US2003-0339968 Applic. Date: 2003-01-09

Abstract: A device is provided for delivering light to the blood supply of a human body through a non-ocular skin area. The device has a plurality of light emitting diodes (LEDs) spaced apart from each other and extending through apertures for emitting light to the body and a power supply connected to the light delivery unit. The device provides wavelengths of light within a specifically-determined range of intensity and a specifically-determined angles of illumination. Devices may be included for controlling and programming the output of the LEDs. A method is provided for delivering light to a non-ocular body region for treating jaundice, breaking down bilirubin and treating other disorders.

Priority: US2003-0339968 Applic. Date: 2003-01- 09

Inventor: SAVAGE JR HENRY C (US); SAVAGE KENT W (US); POWELL STEVEN D (US); SAVAGE HENRY C (US)


Patent No.: US 6816241 B2 Issued: 2004-11-09
Publication No.: US20020041166A1 Published: 2002-04- 11

Title: Led light source-based instrument for non-invasive blood analyte determination

Applicant: SENSYS MEDICAL INC (US)

Application No.: US2001- 0956747 Applic. Date: 2001-09-17

Abstract: A compact, lightweight instrument for non-invasive blood analyte determination employs a light source incorporating an assembly of LED's interconnected within a thermally stable substrate. A large diameter mixer couples the signal to a fiber optic probe for delivering the signal to a tissue measurement site. Back-diffused light is collected and dispersed across an array of photo detectors in a miniature spectrometer instrument. A high-speed DSP executes an algorithm for predicting concentration of a target analyte, which is output to a LCD display. Instrument control is by means of keypad or voice recognition.High conversion efficiency of the light source results in extremely low power dissipation and virtually no heat generation, making incorporation of the light source and the spectrometer into a single unit practicable.; High-speed pulsing of the signal allows application of high-sensitivity, synchronous detection techniques. Speed and flexibility in sequencing LED's allows simultaneous measurement and skin temperature control.

Priority: US2001-0956747 Applic. Date: 2001-09-17; US2000-0235372P Applic. Date: 2000-09-26

Inventor: GRUBISIC DRAGAN (US); HAZEN KEVIN (US); RUCHTI TIMOTHY L (US); ACOSTA GEORGE (US)


Patent No.: US 6818206 B2 Issued: 2004-11-16
Publication No.: US20030129151A1 Published: 2003-07- 10

Title: USE OF AMPHIPHILIC COPOLYMERS TO STABILIZE DISPERSIONS OF INSOLUBLE ORGANIC COMPOUNDS FOR SCREENING OUT UV RADIATION, DISPERSIONS STABILIZED WITH THESE COPOLYMERS AND COSMETIC COMPOSITIONS CONTAINING THEM

Applicant: OREAL (FR)

Application No.: US2002- 0268081 Applic. Date: 2002-10-10

Abstract: The invention relates to the use of at least one amphiphilic copolymer comprising at least one hydrophilic block and at least one hydrophobic block to stabilize dispersions of insoluble organic compounds comprising at least one group that absorbs UV radiation, which is in the form of particles with a mean size of between 10 nm and 5 mum, and also to dispersions stabilized with these amphiphilic copolymers and to cosmetic compositions for topical application, in particular antisun compositions, containing them.

Priority: FR2001-0013114 Applic. Date: 2001-10-11

Inventor: CANDAU DIDIER (FR); AUBERT FABIEN (FR)


Patent No.: US 6825161 B2 Issued: 2004-11-30
Publication No.: US20030207776A1 Published: 2003-11-06

Title: Multi component controlled delivery system for soap bars

Applicant: SALVONA LLC (US)

Application No.: US2002-0286143 Applic. Date: 2002-11-01

Abstract: The present invention relates to an improved controlled delivery system that can be incorporated in soap bars to enhance deposition of active ingredients and sensory markers onto skin. The carrier system also provides controlled release or prolonged release of these actives from the skin over an extended period of time. The controlled delivery system of the present invention comprises substantially free-flowing, powder formed of solid hydrophobic, positively charged, nanospheres of encapsulated active ingredients, that are encapsulated in moisture sensitive microspheres. The high cationic charge density of the nanosphere improves deposition of active ingredients onto skin.; The high cationic charge density on the nanosphere surface is created by incorporating a cationic conditioning agent into the solid hydrophobic matrix of the nanospheres, by incorporating a cationic charge "booster" in the moisture sensitive microsphere matrix, or by using a cationic conditioning agent in the nanosphere matrix in conjunction with a cationic charge "booster" in the microsphere matrix. The invention also pertains to soap products comprising the controlled release system of the present invention.

Priority: US2002-0286143 Applic. Date: 2002-11-01; US2002-0133833 Applic. Date: 2002-04-26

Inventor: SHEFER ADI (US); SHEFER SAMUEL (US)


Patent No.: US 6833132 B1 Issued: 2004-12- 21

Title: Method of stimulating epithelial cells using keratinocyte growth factor (KGF) and method of inhibiting KGF activity

Applicant: US HEALTH (US)

Application No.: US1995-0455975 Applic. Date: 1995-05-31

Abstract: Discoveries are disclosed that show particular aspects of recombinant DNA technology can be used sucessfully to produce hitherto unknown human keratinocyte growth factor (KGF) protein free of other polypeptides. These proteins can be produced in various functional forms from spontaneously secreting cells or from DNA segments introduced into cells. These forms variously enable biochemical and functional studies of this novel protein as well as production of antibodies. Means are described for determining the level of expression of genes for the KGF protein, for example, by measuring mRNA levels in cells or by measuring antigen secreted in extracellular or body fluids.

Priority: US1995-0455975 Applic. Date: 1995-05-31; US1993-0106775 Applic. Date: 1993-08-16; US1991-0780847 Applic. Date: 1991-10-23; US1989 -0304281 Applic. Date: 1989-01-31

Inventor: RUBIN JEFFREY S (US); FINCH PAUL W (US); AARONSON STUART A (US)


Patent No.: US 6846479 B2 Issued: 2005-01-25
Publication No.: US20040076592A1 Published: 2004-04-22

Title: Sunscreen compositions comprising mineral oxides having hydrophobic coatings and glycoside-substituted polydimethylsiloxanes

Applicant: OREAL (FR)

Application No.: US2003-0448345 Applic. Date: 2003-05-30

Abstract: Stable, topically applicable cosmetic/dermatological compositions, notably W/O emulsions, well suited for the UV-photoprotection of the skin, lips and/or the hair, and/or for the makeup of the skin and/or the lips, contain a thus effective amount of at least one mineral oxide having a hydrophobic coating thereon, e.g., coated particulates of an oxide of titanium and/or zinc, and, as a stabilizing agent therefor, a thus effective amount of at least one oxyalkylenated polydimethylsiloxane bearing at least one glycoside residue substituent, formulated into a physiologically acceptable medium therefor.

Priority: FR2000-0015517 Applic. Date: 2000-11-30; WO2001-FR03603 Applic. Date: 2001-11-16

Inventor: LORANT RALUCA (FR); LENNON PAULA (FR)


Patent No.: US 6849250 B2 Issued: 2005-02-01
Publication No.: US20040059119A1 Published: 2004-03-25

Title: Synergistically high SPF photoprotective UV-screening compositions comprising benzotriazole-substituted silicon/dibenzoylmethane/diarylbutadiene compounds

Applicant: OREAL (FR)

Application No.: US2003-0463340 Applic. Date: 2003-06-18

Abstract: Topically applicable, enhanced SPF cosmetic/dermatological UV-screening compositions suited for the photoprotection of the skin and/or hair, comprise, (i) at least one UV-screening benzotriazole- substituted silicon compound, as a first screening agent; (ii) at least one UV-screening dibenzoylmethane compound, as a second screening agent; (iii) at least one 4,4-diarylbutadiene compound, as a third screening agent, formulated into a topically applicable, cosmetically/dermatologically acceptable vehicle therefor.

Priority: FR2000-0016519 Applic. Date: 2000-12-18; WO2001- FR03634 Applic. Date: 2001-11-20

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6855311 B2 Issued: 2005-02- 15
Publication No.: US20040067208A1 Published: 2004-04-08

Title: Photoprotective cosmetic compositions comprising inorganic UV-blocking agents

Applicant: OREAL (FR)

Application No.: US2003-0618701 Applic. Date: 2003-07- 15

Abstract: Stable photoprotective cosmetic emulsions, notably water-in-oil emulsions well suited for the UV-photoprotection of the skin, lips, mucous membranes and/or hair, contain at least one aqueous phase, at least one oily phase, an effective UV-photoprotecting amount of at least one coated or uncoated metal oxide UV-blocking agent and an effective stabilizing amount of at least one amphiphilic oligomer or polymer derived from a polyolefin which also comprises at least one polar moiety, formulated into a physiologically acceptable medium therefor.

Priority: FR2001- 0000484 Applic. Date: 2001-01-15; WO2002-FR00046 Applic. Date: 2002-01-08

Inventor: LENNON PAULA (FR); LORANT RALUCA (FR)


Patent No.: US 6858214 B1 Issued: 2005-02-22

Title: Use of nanoscalar water- soluble beta-(1,3) glucans

Applicant: BIOTEC ASA (NO)

Application No.: US2002-0936747 Applic. Date: 2002-02-15

Abstract: The invention relates to the use of nanoscalar water-soluble beta-(1,3) glucans, which are essentially free from beta-(1,6) links and have particle diameters ranging from 10 to 300 nm for producing cosmetic and/or pharmaceutical preparations. When applied topically, the especially fine dispersion of the particles, compared to prior art glucans, facilitates their rapid penetration of both the stratum corneum of the skin and the keratin fibres of the hair.

Priority: DE1999-1011058 Applic. Date: 1999-03-12; WO2000-EP01829 Applic. Date: 2000-03-03

Inventor: KROPF CHRISTIAN (DE); GRIESBACH UTE (DE); FABRY BERND (DE); ENGSTAD ROLF E (NO)


Patent No.: US 6861078 B2 Issued: 2005-03-01
Publication No.: US20030138507A1 Published: 2003-07-24

Title: Plant extracts with anti-radical type action

Applicant: COGNIS FRANCE SA (FR)

Application No.: US2002-0307977 Applic. Date: 2002-12- 03

Abstract: The use of plant extracts, especially plant extracts with an anti-radical- type action, and a cosmetic or dermo-pharmaceutical composition containing extracts of this type. The use of at least one plant extract whose botanical genus belongs to the group formed by the following: Clidemia, Inga, Sabicea, Astrocaryum, Siparuna, Eperua, Byrsonima, Priva, Coutoubea and Goupia genera; as an active substance which has especially anti-radical-type activities, for preparing a cosmetic or dermopharmaceutical product for local, external use for the skin, the mucous membranes and/or the epithet or appendage structures.

Priority: US2002-0307977 Applic. Date: 2002-12-03; FR1998-0015380 Applic. Date: 1998-12-03; US2001-0857445 Applic. Date: 2001-06- 04

Inventor: PAULY GILLES (FR); MORETTI CHRISTIAN (FR)


Patent No.: US 6863852 B1 Issued: 2005-03- 08

Title: Fluoropolymer extrusions based on novel combinations of process parameters and clay minerals

Applicant: ZEUS IND PRODUCTS INC (US)

Application No.: US2003 -0447253 Applic. Date: 2003-05-28

Abstract: A process for extruding of products from fluoropolymers preferably shaped as rods or tubes which have unique physical and other properties resulting from the addition of nanoparticles under unique processing conditions while also utilizing accurate control of processing parameters such as time and temperature and others according to novel methods.

Priority: US2003-0447253 Applic. Date: 2003-05-28; US2002-0400239P Applic. Date: 2002-05-30; US2002-0385709P Applic. Date: 2002-05-30

Inventor: BALLARD ROBERT L (US); GEORGE ERIC R (US)


Patent No.: US 6869597 B2 Issued: 2005-03-22
Publication No.: US20030077234A1 Published: 2003-04- 24

Title: Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group

Applicant: OREAL (FR); OREAL (US)

Application No.: US2002-0138299 Applic. Date: 2002-05- 06

Abstract: A cosmetic care or makeup composition for keratin materials comprising, in a physiologically acceptable medium, at least one photoprotective agent capable of screening out UV radiation and at least one ester comprising an aromatic group, which is liquid at room temperature, resulting from the esterification of an aromatic acid with at least one hydroxyl group chosen from pendent hydroxyl groups and terminal hydroxyl groups of hydroxylated aliphatic compounds, said hydroxylated aliphatic compounds being chosen from hydroxylated aliphatic acids and esters thereof. Use of the said ester comprising an aromatic group to improve the photoprotective power of compositions intended for protecting the skin and/or the lips and/or integuments against UV radiation.

Priority: FR2001-0006048 Applic. Date: 2001-05-04

Inventor: ARNAUD PASCAL (FR)


Patent No.: US 6872401 B2 Issued: 2005-03-29
Publication No.: US20040009200A1 Published: 2004-01- 15

Title: Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil

Applicant: OREAL (FR)

Application No.: US2003-0400388 Applic. Date: 2003-03-28

Abstract: The invention relates to a cosmetic or dermatological composition containing a carrier comprising at least one fatty phase characterized in that it contains at least one derivative or a mixture of derivatives of 1,7-diphenyl-3,5-heptanedione having a particular structure and at least one oil having, in its structure, at least one amide unit.The invention also relates to its uses in cosmetics and dermatology, in particular for preventing or combating the harmful effects of UV radiation and pollution on human keratinous materials, and more particularly for preventing and/or treating photoaging of the skin.The invention also relates to a method for solubilizing a derivative or a mixture of derivatives of 1,7-diphenyl-3,5-heptanedione having a particular structure with at least one oil having, in its structure, at least one amide unit.

Priority: US2003-0400388 Applic. Date: 2003-03-28; FR2002-0003932 Applic. Date: 2002-03-28; US2002-0377960P Applic. Date: 2002-05-07

Inventor: SEYLER NATHALIE (FR); FIANDINO CECILE (FR); CANDAU DIDIER (FR)


Patent No.: US 6872432 B2 Issued: 2005-03-29
Publication No.: US20020190440A1 Published: 2002-12-19

Title: Hard top produced by method for vacuum pressure forming reinforced plastic articles

Applicant: MAGNA INTERNAT OF AMERICA INC (US)

Application No.: US2002-0219666 Applic. Date: 2002-08- 16

Abstract: A hollow, reinforced, molded automotive hard top is made using a sheet of thermoplastic material with nanoparticles dispersed therein. The particles comprise less than 15% of total volume of the plastic sheet, at least 50% of the particles have a thickness less than about 20 layers, and at least 99% of the particles have a thickness of less than about 30 layers. The sheet is preheated and molded in an assembly having mold surfaces corresponding to the hard top configuration. Vacuum is applied to one side of the assembly and pressurized gas is applied to the opposite side of the assembly to force the sheet into conformity with the mold surfaces. After cooling, the conformed sheet is transferred to another mold assembly, where a reinforced plastic melt having a blowing agent is applied. Together, the solidified melt and the conformed plastic sheet form the hard top.

Priority: US2002-0219666 Applic. Date: 2002-08-16; US2001-0857768 Applic. Date: 2001-06-11; US1998-0113064P Applic. Date: 1998-12-21

Inventor: WILSON PHILLIP S (US)


Patent No.: US 6875426 B2 Issued: 2005-04-05
Publication No.: US20030228268A1 Published: 2003-12- 11

Title: Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent

Applicant: OREAL (FR)

Application No.: US2003-0400551 Applic. Date: 2003-03-28

Abstract: The present invention relates to a cosmetic and/or dermatological composition more particularly intended for artificially tanning and/or browning the skin and comprising, in a cosmetically acceptable support, at least one derivative or a mixture of derivatives of 1,7-bisphenyl heptane-3,5-dione of particular structure and at least one self-tanning agent.The present invention also relates to a cosmetic treatment process for artificially tanning or browning the skin and to the use of at least one derivative or a mixture of derivatives of 1,7-bisphenyl heptane-3,5-dione of particular structure for improving the coloration and/or stability of a self- tanning agent.The invention also relates to the uses of these compositions for giving the skin a coloration close to that of a natural skin tan.

Priority: US2003-0400551 Applic. Date: 2003-03-28; FR2002-0003934 Applic. Date: 2002-03-28; US2002-0377958P Applic. Date: 2002-05- 07

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6878381 B2 Issued: 2005-04-12
Publication No.: US20020155075A1 Published: 2002-10-24

Title: Resorcinol composition

Applicant: PFIZER (US)

Application No.: US2002-0061040 Applic. Date: 2002-01-30

Abstract: The present invention relates to the use of a resorcinol derivative, i.e., 4-(2,4-dihydroxyphenyl)cyclohexanol, or a pharmaceutically acceptable salt thereof, as a skin lightening agent.

Priority: US2002-0061040 Applic. Date: 2002-01-30; US2000-0525643 Applic. Date: 2000-03-15; US1999-0125553P Applic. Date: 1999-03- 22

Inventor: COLLINGTON ERIC WILLIAM (GB)


Patent No.: US 6887380 B2 Issued: 2005-05-03
Publication No.: US20030098274A1 Published: 2003-05-29

Title: Silicone-coated organic solvent resistant polyamide composite nanofiltration membrane, and method for preparing the same

Applicant: KOREA RES INST CHEM TECH (KR); KOREA RES INST CHEM TECH (US)

Application No.: US2002-0147071 Applic. Date: 2002-05-17

Abstract: The present invention relates to a silicone-coated organic solvent resistant polyamide composite nanofiltration membrane and a method for preparing the same. More particularly, the present invention relates to a nanofiltration composite membrane that is not only rejection rate superior but also organic solvent stable and flux excellent, prepared by coating with silicone during the process of interfacial polymerization of polyamide on the surface of porous support; and a method for producing it.

Priority: KR2001-0064598 Applic. Date: 2001-10-19

Inventor: LEE KEW-HO (KR); KIM IN-CHUL (KR); YUN HYUNG-GU (KR)


Patent No.: US 6901930 B2 Issued: 2005-06-07
Publication No.: US20030136408A1 Published: 2003-07-24

Title: Wearable electro-ionic protector against inhaled pathogens

Application No.: US2002-0283104 Applic. Date: 2002-10-28

Abstract: A device for removing airborne contaminants and inhaled biopathogens, particularly particulate or aerosol contaminants, from respired air that can be either stationary or incorporated into a garment or accessory worn upon the body. In a preferred embodiment, a negative electrode is connected to voltage multiplier and modulation circuit and then to a discharge electrode having an electron emissive surface disposed near the wearer's airway. The positive (counter) electrode is similarly disposed away from the airway such as, for example, near the forehead. Electrons, ejected from the electron emissive surface, transfer a negative charge to airborne particulate contaminants which are accelerated toward, and collected by, the counter electrode.

Priority: US2002- 0283104 Applic. Date: 2002-10-28; US2001-0337508P Applic. Date: 2001-11-08

Inventor: HENLEY JULIAN L (US)


Patent No.: US 6902722 B2 Issued: 2005-06-07
Publication No.: US20040228814A1 Published: 2004-11-18

Title: Aqueous antisun/sunscreen compositions comprising amphiphilic 2- Acrylamidomethylpropanesulfonic acid polymers and water-soluble silicones

Applicant: OREAL (FR)

Application No.: US2004-0823669 Applic. Date: 2004-04- 14

Abstract: Photoprotective compositions well suited for the photoprotection of the skin, lips and/or hair against the damaging effect of UV-radiation comprise at least one aqueous phase and at least one system for screening out UV-radiation, and which also contain: (a) at least one partially or totally neutralized, crosslinked or non-crosslinked amphiphilic polymer of 2- acrylamidomethylpropanesulfonic acid (AMPS), and (b) at least one water-soluble silicone comprising at least one terminal or pendent monovalent polyoxyalkylene group.

Priority: US2004-0823669 Applic. Date: 2004-04-14; FR2003-0004650 Applic. Date: 2003-04-14; US2003-0468053P Applic. Date: 2003 -05-06

Inventor: CANDAU DIDIER (FR); BOUTELET KARL (FR); SEYLER NATHALIE (FR)


Patent No.: US 6902737 B2 Issued: 2005-06-07
Publication No.: US20030087967A1 Published: 2003-05-08

Title: Translucent nanoemulsion, production method, and uses thereof in the cosmetic, dermatological and/or ophthalmological fields

Applicant: OREAL (FR)

Application No.: US2002- 0182401 Applic. Date: 2002-07-30

Abstract: The nanoemulsion according to the invention comprises an oily phase dispersed in an aqueous phase, having oil globules with a number- average size less than 100 nm, characterized in that it contains a ternary surfactant system comprising: a) a mixture of at least two nonionic surfactants comprising at least one ethoxylated fatty ester comprising 8 to 100 ethylene oxide units and at least one fatty acid ester of sorbitan; and b) at least one ionic surfactant chosen from alkali metal salts of cetyl phosphate and alkali metal salts of palmitoyl sarcosinate. Use in the manufacture of cosmetic, dermatological and ophthalmological compositions.

Priority: FR2001-0000696 Applic. Date: 2001-01-18; WO2002-FR00130 Applic. Date: 2002-01-14

Inventor: QUEMIN ERIC (FR)


Patent No.: US 6902743 B1 Issued: 2005-06- 07

Title: Therapeutic treatment and prevention of infections with a bioactive material(s) encapuslated within a biodegradable-bio-compatable polymeric matrix

Applicant: US ARMY (US)

Application No.: US1998-0055505 Applic. Date: 1998-04- 06

Abstract: Novel burst-free, sustained release biocompatible and biodegrable microcapsules which can be programmed to release their active core for variable durations ranging from 1-100 days in an aqueous physiological environment. The microcapsules are comprised of a core of polypeptide or other biologically active agent encapsulated in a matrix of poly(lactide/glycolide) copolymer having a molar composition of lactide/glycolide from 90/10 to 40/60, which may contain a pharmaceutically-acceptable adjuvant, as a blend of uncapped free carboxyl end group and end-capped forms ranging to ratios from 100/0 to 1/99.

Priority: US1998-0055505 Applic. Date: 1998- 04-06; US1997-0920326 Applic. Date: 1997-08-21; US1997-0088961 Applic. Date: 1997-07-17; US1997- 0788734 Applic. Date: 1997-01-23; US1996-0086988 Applic. Date: 1996-08-16; US1996-0675895 Applic. Date: 1996-07-05; US1996-0598874 Applic. Date: 1996-02-09; US1996-0590973 Applic. Date: 1996-01-24; US1995-0446149 Applic. Date: 1995-05-22; US1995-0446148 Applic. Date: 1995-05- 22

Inventor: SETTERSTROM JEAN A (US); TICE THOMAS R (US); JACOB ELLIOT (US); REID ROBERT H (US); VAN HAMONT JOHN (US); BOEDECKER EDGAR C (US); JEYANTHI RAMASSUBBU (US); FRIDEN PHIL (US); ROBERTS F DONALD (US); MCQUEEN CHARLES E (US); BHATTACHARJEE APURBA (US); CROSS ALAN (US); SADOFF JERALD (US); ZOLLINGER WENDELL (US)


Patent No.: US 6905674 B2 Issued: 2005-06-14
Publication No.: US20040228815A1 Published: 2004-11-18

Title: Aqueous photoprotective compositions comprising acrylamido-2-methylpropanesulfonic acid polymers and 4,4-diarylbutadiene UV-A sunscreens

Applicant: OREAL (FR)

Application No.: US2004-0823670 Applic. Date: 2004-04-14

Abstract: Photoprotective compositions, e.g., oil-in-water or water- in-oil emulsions, well suited for the photoprotection of the skin, lips and/or hair against the damaging effects of UV-radiation, comprise at least one aqueous phase, at least one oily phase, at least one partially or completely neutralized, crosslinked or non-crosslinked water-soluble or water-dispersible acrylamido-2-methylpropanesulfonic acid (AMPS) polymer and at least one UV radiation-screening system, said at least one screening system comprising at least one 4,4-diarylbutadiene UV-A-screening agent

Priority: US2003-0468089P Applic. Date: 2003-05-06; FR2003-0004647 Applic. Date: 2003-04-14; US2004-0823670 Applic. Date: 2004-04-14

Inventor: L ALLORET FLORENCE (FR)


Patent No.: US 6916465 B2 Issued: 2005-07-12
Publication No.: US20030133891A1 Published: 2003-07- 17

Title: Deodorizing preparations containing nanosacle chitosans and/or chitosan derivatives

Applicant: COGNIS DEUTSCHLAND GMBH (DE)

Application No.: US2002 -0239553 Applic. Date: 2002-09-23

Abstract: A deodorizing composition containing an ingredient selected from the group consisting of a nanoscale chitosan having a particle diameter of from about 1 to 300 nm, a nanoscale chitosan derivative having a particle diameter of from about 1 to 300 nm, and mixtures thereof.

Priority: DE2000-1014529 Applic. Date: 2000-03-23; WO2001-EP02863 Applic. Date: 2001-03-14

Inventor: PANZER CLAUDIA (DE); WACHTER ROLF (DE)


Patent No.: US 6916872 B2 Issued: 2005-07-12
Publication No.: US20030207978A1 Published: 2003-11-06

Title: Non-spherical nanopowder derived nanocomposites

Applicant: NANOPRODUCTS CORP (US)

Application No.: US2003-0449282 Applic. Date: 2003-05-30

Abstract: Nanocomposites from nanofillers with preferred form of whiskers, rods, plates and fibers are disclosed. The matrix composition described includes polymers, ceramics and metals. The composition disclosed include inorganic, organic and metallic. These nanocomposites are useful in wide range of applications given their unusual properties such as refractive index, transparency to light, reflection characteristics, resistivity, permittivity, permeability, coercivity, B-H product, magnetic hysteresis, breakdown voltage, skin depth, curie temperature, dissipation factor, work function, band gap, electromagnetic shielding effectiveness, radiation hardness, chemical reactivity, thermal conductivity, temperature coefficient of an electrical property, voltage coefficient of an electrical property, thermal shock resistance, biocompatibility, and wear rate.

Priority: US2003-0449282 Applic. Date: 2003-05-30; US2001-0790036 Applic. Date: 2001-02-20; US1998-0083893 Applic. Date: 1998- 05-22; US1996-0739257 Applic. Date: 1996-10-30; US1996-0730661 Applic. Date: 1996-10-11; US1996- 0706819 Applic. Date: 1996-09-03; US1996-0707341 Applic. Date: 1996-09-03; US1997-0049077P Applic. Date: 1997-06-09; US1997-0069936P Applic. Date: 1997-12-17; US1998-0079225P Applic. Date: 1998-03- 24

Inventor: YADAV TAPESH (US); KOSTELECKY CLAYTON (US)


Patent No.: US 6919071 B2 Issued: 2005-07-19
Publication No.: US20040191189A1 Published: 2004-09-30

Title: Sunscreen milk

Applicant: EXPANSCIENCE LAB (FR)

Application No.: US2003-0240718 Applic. Date: 2003-11-20

Abstract: The invention concerns a cosmetic or dermatological composition for protection against ultraviolet radiation, based on inorganic screening agent, characterized in that it comprises a water-in-oil emulsion containing a combination of at least a particulate inorganic sunscreening agent, selected among the group consisting of titanium dioxide, zinc oxide and mixtures thereof, and at least an emulsifier selected among the group consisting of silicone derivatives with glycosidic constituent, the particulate screening agent being homogeneously dispersed in the water-in-oil emulsion.

Priority: FR2000-0004360 Applic. Date: 2000-04-05; WO2001- FR01007 Applic. Date: 2001-04-04

Inventor: CHOULOT JEAN-CHRISTOPHE (FR); PETIT NATHALIE (FR); MSIKA PHILIPPE (FR); FERRARIS PATRICIA (FR); RIBES DELPHINE (FR); HILAIRE JOCELYNE (FR); BERNARD RIBES (FR)


Patent No.: US 6921777 B2 Issued: 2005-07-26
Publication No.: US20030012803A1 Published: 2003-01- 16

Title: Heteroethynylenic compounds and pharmaceutical and cosmetic compositions containing them

Applicant: GALDERMA RES & DEV (FR)

Application No.: US2002-0192651 Applic. Date: 2002-07-11

Abstract: The invention relates to novel heteroethynylenic compounds having the general formula (I): as well as to the use of these compounds in pharmaceutical compositions intended for use in human or veterinary medicine (dermatological, rheumatic, respiratory, cardiovascular and ophthalmological complaints in particular), or alternatively in cosmetic compositions.

Priority: US2002-0192651 Applic. Date: 2002-07-11; FR1998-0003977 Applic. Date: 1998-03-31; WO1999-FR00727 Applic. Date: 1999-03-29; US2000-0424816 Applic. Date: 2000-02- 07

Inventor: DIAZ PHILIPPE (FR); BERNARDON JEAN-MICHEL (FR)


Patent No.: US 6923762 B1 Issued: 2005-08- 02

Title: Venoscope apparatus

Application No.: US2002-0278301 Applic. Date: 2002-10-22

Abstract: An improved instrument for viewing subcutaneous venous structure, known as a VENOSCOPE, which includes a clamshell housing, having a first fixed arm extending therefrom, and a second movable arm captured by upper and lower portions of the housing; a first high intensity plurality of white and red LEDs positioned at the end of the first arm, and a second high intensity plurality of high intensity red and white LED positioned at the end of the second arm, and a battery positioned within the housing for selectively provided electrical energy to the red and white LEDs, so that a more defined and intensely illuminated field of visualization between structures below the skin and the surrounding subcutaneous tissue is defined. Additional embodiments include a tube or handle connected to a head having multiple arms or a single arm with multiple LEDs.

Priority: US2002-0278301 Applic. Date: 2002-10-22; US2001-0334821P Applic. Date: 2001-11-01

Inventor: CREAGHAN JR FRANK C (US)


Patent No.: US 6939568 B2 Issued: 2005-09-06
Publication No.: US20030054046A1 Published: 2003-03-20

Title: Treatment of inflammatory skin conditions

Applicant: NUCRYST PHARM CORP (CA)

Application No.: US2002- 0131511 Applic. Date: 2002-04-23

Abstract: The invention relates to the use of one or more antimicrobial metals, most preferably silver, preferably formed with atomic disorder, and preferably in a nanocrystalline form, for the treatment of inflammatory skin conditions. The nanocrystalline antimicrobial metal of choice may be used in the form of a nanocrystalline coating of one or more antimicrobial metals, a nanocrystalline powder of one or more antimicrobial metals, or a solution containing dissolved species from a nanocrystalline powder or coating of one or more antimicrobial metals.

Priority: US2002-0131511 Applic. Date: 2002-04-23; US2001-0840637 Applic. Date: 2001-04-23; US2001-0285884P Applic. Date: 2001-04-23

Inventor: BURRELL ROBERT EDWARD (CA); YIN HUA QING (CA)


Patent No.: US 6945723 B1 Issued: 2005-09-20

Title: Packaging and application device

Applicant: OREAL (FR)

Application No.: US2000-0666450 Applic. Date: 2000-09-21

Abstract: Packaging and application device comprising a container having an internal space ( 12 ) in which the product (P) is contained, an application element ( 16 ), a housing ( 14 ) for housing the application element and a permeable wall ( 23 ) placed between the said housing and the internal space containing the product. The application element and the housing are both designed in such a way that the application element has, when it is in the said housing, at least one surface portion ( 16 a) located, without any appreciable axial compression, opposite an opening ( 25 ) in the permeable wall.; The internal space is a variable-volume space, compression means being provided for making the said internal volume pass selectively from a first volume, greater than the volume of product, to a second volume, smaller than the first, this reduction in volume being accompanied by an overpressure which is conducive to transferring product through the said permeable wall towards the application element.

Priority: US2000-0666450 Applic. Date: 2000-09- 21

Inventor: GUERET JEAN-LOUIS (FR)


Patent No.: US 6955639 B2 Issued: 2005-10-18
Publication No.: US20040181114A1 Published: 2004-09-16

Title: Methods of enhancing radiation effects with metal nanoparticles

Applicant: NANOPROBES INC (US)

Application No.: US2003-0387059 Applic. Date: 2003-03-12

Abstract: The present invention provides methods of using metal nanoparticles 0.5 to 400 nm in diameter to enhance the dose and effectiveness of x-rays or of other kinds of radiation in therapeutic regimes of ablating a target tissue such as tumor. The metal nanoparticles can be administered intravenously, intra- arterially, or locally to achieve specific loading in and around the target tissue. The metal nanoparticles can also be linked to chemical and/or biochemical moieties which bind specifically to the target tissue. The enhanced radiation methods can also be applied to ablate unwanted tissues or cells ex vivo.

Priority: US2003-0387059 Applic. Date: 2003-03-12; US1998-0094669P Applic. Date: 1998-07-30; US1999-0363204 Applic. Date: 1999-07-29

Inventor: HAINFELD JAMES F (US); SLATKIN DANIEL N (US)


Patent No.: US 6955803 B2 Issued: 2005-10-18
Publication No.: US20040062728A1 Published: 2004-04-01

Title: Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers

Applicant: OREAL (FR)

Application No.: US2003-0616947 Applic. Date: 2003-07-11

Abstract: Photoprotective cosmetic/dermatological compositions well suited for the UV-photoprotection of human skin and/or hair, comprise (a) at least one organic UV- screening agent and (b) an SPF-improving amount of at least one amphiphilic polymerizate of at least one ethylenically unsaturated monomer which comprises a sulfonic group, whether in the free acid or in partially or totally neutralized state, and which amphiphilic polymerizate also comprises at least one hydrophobic moiety.

Priority: FR2001-0000334 Applic. Date: 2001-01-11; WO2002-FR00030 Applic. Date: 2002-01-04

Inventor: BOUTELET KARL (FR); CANDAU DIDIER (FR)


Patent No.: US 6957094 B2 Issued: 2005-10-18
Publication No.: US20030166997A1 Published: 2003-09-04

Title: Examination of scattering properties of biological tissue

Applicant: NON INVASIVE TECHNOLOGY INC (US)

Application No.: US2002-0299598 Applic. Date: 2002-11- 19

Abstract: This invention is a scheme for monitoring a solute in a biological system comprising the steps of delivering light into a biological system ( 12 ) containing a solute, the light having a wavelength selected to be in a range wherein the solute is substantially non-absorbing; detecting at least first and second portions of the delivered light, the first portion having traveled through the biological system along one or more paths characterized by a first average path length, and the second portion having traveled through the biological system along one or more paths characterized by a second average path length that is greater than the first average path length; and comparing the first and second portions of the delivered light to monitor concentration of the solute in the biological system.; Also described are schemes for monitoring low molecular weight polyhydroxy solutes, generally sugars (mannitol, fructose, sucrose, glucose, sorbitol), alcohols (methanol, ethanol, propanediol), and electrolytes (sodium, potassium, magnesium, calcium, and chloride ions).

Priority: US2002-0299598 Applic. Date: 2002-11-19; US1997-0849203 Applic. Date: 1997-11-17; US1994-0349839 Applic. Date: 1994-12-02; WO1995-US15666 Applic. Date: 1995-12- 04

Inventor: CHANCE BRITTON (US); LIU HANLI (US)


Patent No.: US 6979491 B2 Issued: 2005-12-27
Publication No.: US20030190851A1 Published: 2003-10-09

Title: Antimicrobial yarn having nanosilver particles and methods for manufacturing the same

Applicant: CC TECHNOLOGY INVEST CO LTD (CN)

Application No.: US2002-0106033 Applic. Date: 2002-03- 27

Abstract: The present invention provides a yarn with antimicrobial effects. The antimicrobial antifungal effect of the yarn is derived from nanosilver particles (diameter between 1 and 100 nm) which are adhered to the yarn. The yarn contains fibers which are made of cotton, linen, silk, wool, leather, blending fabric, synthetic fiber, or any combination thereof. The yarn can be used to make cloth to be used particularly for treating patients with burns or wound. The cloth made from the antimicrobial yarn can be further used to make clothes such as underwears, socks, shoe cushions, shoe linings, bed sheets, pillow cases, towels, women hygiene products, laboratory coats, and medical robes. The present invention also provides a method for making the antimicrobial yarn.

Priority: US2002-0106033 Applic. Date: 2002-03-27

Inventor: YAN JIXIONG (CN); CHENG JIACHONG (CN)


Patent No.: US 6994844 B2 Issued: 2006-02-07
Publication No.: US20040052738A1 Published: 2004-03- 18

Title: Photostable UV-screening compositions comprising dibenzoylmethane/diarylbutadiene compounds

Applicant: OREAL (FR)

Application No.: US2003-0463326 Applic. Date: 2003-06-18

Abstract: Topically applicable, photostable cosmetic/dermatological UV-screening compositions comprise (a) at least one photolabile UV- screening dibenzoylmethane compound and (b) a dibenzoylmethane photostabilizing amount of at least one 4,4-diarylbutadiene compound, formulated into a topically applicable, cosmetically/dermatologically acceptable support therefor; the weight ratio of the 4,4-diarylbutadiene compound(s) to the diarylbutadiene compound(s) is characteristically greater than 2.5 and the subject compositions are advantageously devoid of any cinnamate sunscreen.

Priority: FR2000-0016518 Applic. Date: 2000-12-18; WO2001-FR03635 Applic. Date: 2001-11-20

Inventor: CANDAU DIDIER (FR)


Patent No.: US 6997909 B2 Issued: 2006-02-14
Publication No.: US20040024363A1 Published: 2004-02-05

Title: Low profile combination device for gastrostomy or jejunostomy applications having anti-granuloma formation characteristics

Applicant: PHILADELPHIA CHILDREN HOSPITAL (US)

Application No.: US2003-0420450 Applic. Date: 2003-04-22

Abstract: A combination device for gastrostomy or jejunostomy usage having a retaining member, an elongated member having a gastrostomy lumen and a jejustomy lumen, and an inflatable balloon mounted on the elongated member. The retaining member is of a low profile and is arranged to be located on the skin adjacent a stoma in the abdominal wall through which the elongated member extends. The balloon seals the stoma about the elongated member. The retaining member includes at least one access port to communicate with respective ones of the lumens. The device, related compositions, and processes can prevent and/or treat granulomas.

Priority: US2003-0420450 Applic. Date: 2003-04-22; US2002-0374401P Applic. Date: 2002-04-22; US2002-0374537P Applic. Date: 2002-04-22

Inventor: GOLDBERG ELIZABETH A (US)


Patent No.: US 6998421 B2 Issued: 2006-02-14
Publication No.: US20030109580A1 Published: 2003-06- 12

Title: Compounds and methods for inhibition of phospholipase A2 and cyclooxygenase - 2

Applicant: BIOZONE LAB INC (US)

Application No.: US2002-0229195 Applic. Date: 2002-08-26

Abstract: The present invention comprises a group of related lipid molecules, and methods for their use, that maybe used to treat inflammation and certain inflammation related diseases. The group of related lipid molecules are capable of inhibiting certain enzyme systems including phospholipase A2, and cyclooxygenase-2. The group of related lipid molecules of the invention may be characterized by specific structural characteristics, or by specific biological activity, including inhibition of the previously listed enzymes.

Priority: US2002-0229195 Applic. Date: 2002-08-26; US2001-0877334 Applic. Date: 2001-06-07

Inventor: KELLER BRIAN (US)


Patent No.: US 6998426 B2 Issued: 2006-02-14
Publication No.: US20020035182A1 Published: 2002-03- 21

Title: Nanoemulsion containing nonionic polymers, and its uses

Applicant: OREAL (FR)

Application No.: US2001-0903768 Applic. Date: 2001-07- 13

Abstract: These objects and others may be accomplished with the present invention, the first embodiment of which provides an oil-in-water nanoemulsion, which includes: an oily phase dispersed in an aqueous phase; (i) at least one amphiphilic lipid selected from the group including nonionic amphiphilic lipids, anionic amphiphilic lipids, and combinations thereof; and (ii) at least one water- soluble nonionic polymer selected from the group including homopolymers and copolymers of ethylene oxide; polyvinyl alcohols; homopolymers and copolymers of vinylpyrrolidone; homopolymers and copolymers of vinylcaprolactam; homopolymers and copolymers of polyvinyl methyl ether; neutral acrylic homopolymers and copolymers; C1-C2 alkyl celluloses and their derivatives; C1-C3 alkyl guar; C1-C3 hydroxyalkyl guar; and combinations thereof; wherein a ratio of the weight of the oily phase to the weight of the amphiphilic lipid (i) ranges from 1.2 to 10; and wherein the oily phase includes oil globules having a number-average size of less than 100 nm. The nanoemulsion obtained is preferably transparent and stable on storage. It may form a composition for topical, preferably cosmetic or dermatological compositions, pharmaceutical compositions and ophthalmological compositions.

Priority: FR2000-0009222 Applic. Date: 2000-07-13

Inventor: L ALLORET FLORENCE (FR); AUBRUN-SONNEVILLE ODILE (FR); SIMONNET JEAN-THIERRY (FR)


Patent No.: US 7004928 B2 Issued: 2006-02-28
Publication No.: US20030153900A1 Published: 2003-08-14

Title: Autonomous, ambulatory analyte monitor or drug delivery device

Applicant: ROSEDALE MEDICAL INC (US); SARNOFF CORP (US)

Application No.: US2002-0131268 Applic. Date: 2002-04-23

Abstract: The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface.; The invention provides for autonomous operation, that is, without intervention of the user. The invention can optionally provide for calibration without intervention of the user. The invention can also provide for semi-continuous monitoring for day and night time. The invention can provide for up to four, or more, weeks of operation. The invention can provide for a device that is relative small in size, and therefore unobtrusive. The invention can also provide for device with remote control and interactive electronics. The invention may be also used for the delivery of various pharmaceutical agents including high potency drugs to minimize patient intervention and minimize discomfort.

Priority: US2002-0131268 Applic. Date: 2002-04-23; US2002-0355195P Applic. Date: 2002-02-08

Inventor: ACETI JOHN GREGORY (US); MCBRIDE STERLING EDUARD (US); MORONEY III RICHARD MORGAN (US); GREGORY CHRISTOPHER CARTER (US); ZANZUCCHI PETER JOHN (US); MORONEY RICHARD MORGAN (US)


Patent No.: US 7012101 B2 Issued: 2006-03-14
Publication No.: US20030181533A1 Published: 2003-09- 25

Title: Artificial tanning emulsions comprising sorghum extracts/organomodified silicones

Applicant: OREAL (FR)

Application No.: US2003-0338713 Applic. Date: 2003-01-09

Abstract: Topically applicable, cosmetic/dermatological artificial tanning emulsions devoid of certain flavylium salts include (a) at least one aqueous phase and (b) at least one fatty phase, (c) an effective artificial tanning amount of at least one sorghum extract, and (d) at least one organomodified silicone.

Priority: US2003-0338713 Applic. Date: 2003-01- 09; FR2002-0000254 Applic. Date: 2002-01-10; US2002-0350383P Applic. Date: 2002-01- 24

Inventor: SEYLER NATHALIE (FR); ELGUIDJ IRENE (FR); CANDAU DIDIER (FR)


Patent No.: US 7015624 B1 Issued: 2006-03-21

Title: Non-uniform thickness electroactive device

Applicant: NASA (US)

Application No.: US2000-0696526 Applic. Date: 2000-10- 23

Abstract: An electroactive device comprises at least two layers of material, wherein at least one layer is an electroactive material and wherein at least one layer is of non-uniform thickness. The device can be produced in various sizes, ranging from large structural actuators to microscale or nanoscale devices. The applied voltage to the device in combination with the non-uniform thickness of at least one of the layers (electroactive and/or non-electroactive) controls the contour of the actuated device. The effective electric field is a mathematical function of the local layer thickness. Therefore, the local strain and the local bending/torsion curvature are also a mathematical function of the local thickness. Hence the thinnest portion of the actuator offers the largest bending and/or torsion response. Tailoring of the layer thicknesses can enable complex motions to be achieved.

Priority: US2000-0696526 Applic. Date: 2000-10-23; US1999-0161113P Applic. Date: 1999-10-22

Inventor: SU JI (US); HARRISON JOYCELYN S (US)


Patent No.: US 7033349 B2 Issued: 2006-04- 25
Publication No.: US20040199152A1 Published: 2004-10-07

Title: Method of amplifying a beneficial selective skin response to light energy

Application No.: US2004-0830391 Applic. Date: 2004-04-21

Abstract: A method of altering the appearance of a region of skin is disclosed. The method includes applying a sensitizing wavelength of light the region, and applying a treatment wavelength of light to the skin, wherein the treatment wavelength is a shorter wavelength than the sensitizing wavelength. The application of the sensitizing wavelength of light and the treatment wavelength of light results in a change in a physical property of the skin.

Priority: US2004-0830391 Applic. Date: 2004-04-21; US2001-0024270 Applic. Date: 2001-12-17; US2000-0256555P Applic. Date: 2000-12-18; US2000-0258006P Applic. Date: 2000-12- 20

Inventor: KEY DOUGLAS J (US)


Patent No.: US 7033382 B2 Issued: 2006-04-25
Publication No.: US20040093047A1 Published: 2004-05-13

Title: System and method for tissue treatment

Applicant: BIOCELLULASE INC (US)

Application No.: US2003-0701991 Applic. Date: 2003-11-05

Abstract: A system and method for the treatment of body tissue is provided that includes a radiation-emitting device and a massaging mechanism. In accordance with one embodiment, the radiation-emitting device is a laser and the massaging mechanism is an automated mechanical massaging mechanism. The radiation-emitting device can emit radiation in one or both of the visible and infrared wavelengths. The radiation-emitting device can emit radiation in a concentric combination of infrared and visible laser light. The method of using the tissue treatment system includes exposing a skin surface of a patient to radiation emitted from the radiation-emitting device at predetermined wavelengths for predetermined periods of time. The method further provides for massaging the exposed skin surface of the patient with the massaging mechanism.; The tissue treatment system can be utilized to effect the reduction of excess cellulite.

Priority: US2003- 0701991 Applic. Date: 2003-11-05; US2001-0000459 Applic. Date: 2001-11-02; US2000-0245948P Applic. Date: 2000-11-03

Inventor: LACH ELLIOT (US)


Patent No.: US 7045546 B2 Issued: 2006-05-16
Publication No.: US20040242544A1 Published: 2004-12-02

Title: Stabilized derivatives of ascorbic acid-3-phosphate

Applicant: TAGRA BIOTECHNOLOGIES LTD (IL)

Application No.: US2004-0484689 Applic. Date: 2004-07-15

Abstract: Novel derivatives of ascorbic acid and compositions comprising them are provided. The novel derivatives are of the following general formula (I): where R1 is a C2-C22 saturated or unsaturated fatty acid residues, amino acid residues, or a C1-C17 alkyl ; R2 is a group of the following formula (II) wherein R5 or R6 are the same or different and represent hydrogen, a C1-C4 alkyl, or R5 is C1-C4 alkyl group and R6 is a metal cation or ammonium cation; R3 or R4 are the same or different and represent hydrogen, C2-C22 saturated or unsaturated fatty acid residues, amino acid residues, or a C1-C17 alkyl.

Priority: WO2001 -IL00690 Applic. Date: 2001-07-26

Inventor: BABTSOV VLADIMIR (IL); SHAPIRO YURY (IL); KVITNITSKY EMMA (IL); BELAKHOV VALERY (IL)


Patent No.: US 7046439 B2 Issued: 2006-05-16
Publication No.: US20040233526A1 Published: 2004-11-25

Title: Optical element with nanoparticles

Applicant: EASTMAN KODAK CO (US)

Application No.: US2003- 0443387 Applic. Date: 2003-05-22

Abstract: Disclosed is an optical element comprising a substrate with surface features on a surface thereof having an Ra of from 3 to 200 micrometers containing a dispersion of minute particles having a particle size dimension less than 100 nanometers.

Priority: US2003-0443387 Applic. Date: 2003-05-22

Inventor: KAMINSKY CHERYL J (US); BOURDELAIS ROBERT P (US); IRVIN GLEN C (US)


Patent No.: US 7052652 B2 Issued: 2006-05-30
Publication No.: US20040191119A1 Published: 2004-09-30

Title: Analyte concentration detection devices and methods

Applicant: ROSEDALE MEDICAL INC (US)

Application No.: US2003-0394230 Applic. Date: 2003-03-24

Abstract: Arrangements for the detection of the presence and/or concentration of an analyte in a sample of bodily fluid include diffuse transmission, diffuse reflection and edge or waveguide illumination arrangements. A vertical flow assay arrangement and/or technique is also disclosed, and includes a detection component that can be in the form of an array of optical detection elements. A number of assay pad constructions are described which may include at least one or more of the following components: a prefilter component, a reflective component, a membrane component, a reagent component, a mesh component, and a component to prevent lateral spreading.

Priority: US2003-0394230 Applic. Date: 2003-03- 24

Inventor: ZANZUCCHI PETER J (US); MCBRIDE STERLING E (US); DESAI NITIN V (US); HO WEN (US); VARMA BOBBY (US)


Patent No.: US 7060192 B2 Issued: 2006-06-13
Publication No.: US20030212346A1 Published: 2003-11-13

Title: Methods of fabricating physiological sample collection devices

Applicant: LIFESCAN INC (US)

Application No.: US2002-0143127 Applic. Date: 2002-05-09

Abstract: Methods of fabricating devices for collecting a sample of physiological and for measuring a characteristic, e.g., an analyte concentration, of the sampled physiological sample. The devices are in the form of a test strip which include a biosensor and at least one skin-piercing element which is a planar extension of a portion of the biosensor. The fabrication methods provide various or forming the test strip and the skin-piercing element.

Priority: US2002-0143127 Applic. Date: 2002-05-09

Inventor: YUZHAKOV VADIM V (US); MCALLISTER DEVIN V (US); OLSON LORIN (US); LEONG KOON-WAH (US); TEODORCZYK MARIA (US); KISER ERNEST (US)


Patent No.: US 7066929 B1 Issued: 2006-06-27

Title: Selective photothermolysis

Applicant: RADIANCY INC (US)

Application No.: US2002- 0148740 Applic. Date: 2002-05-30

Abstract: Performing selective photothermolysis of sub-cutaneous tissue by using a plurality of beams of narrow band electro-magnetic radiation, where each of the beams have energy that is insufficient to heat the tissue that they strike to a temperature high enough to destroy such tissue, but by directing the individual beams to overlap at the target sufficient heat is generated to destroy the target tissue.

Priority: WO1999-IL00658 Applic. Date: 1999-12-02

Inventor: AZAR ZION (IL); SHALEV PINCHAS (IL)


Patent No.: US 7067152 B2 Issued: 2006-06-27
Publication No.: US20030198680A1 Published: 2003-10-23

Title: Multi component moisture triggered controlled release system that imparts long lasting cooling sensation on the target site and/or provides high impact fragrance or flavor burst

Applicant: SALVONA LLC (US)

Application No.: US2002-0211727 Applic. Date: 2002-08-02

Abstract: The present invention relates to cosmetic formulations comprising a multi component controlled release system that imparts long lasting cooling sensation and/or provides high odor or flavor intensity (i.e., high impact fragrance or flavor burst) in response to moisture. The controlled delivery system of the present invention is substantially free-flowing powder formed of solid hydrophobic nano-spheres that are encapsulated in a moisture sensitive micro-spheres.

Priority: US2002-0211727 Applic. Date: 2002-08-02; US2002-0124207 Applic. Date: 2002-04-17

Inventor: SHEFER ADI (US); SHEFER SAMUEL DAVID (US)


Patent No.: US 7078060 B2 Issued: 2006-07-18
Publication No.: US20030203046A1 Published: 2003-10- 30

Title: Solutions and aerosols of metal-containing compounds

Applicant: NUCRYST PHARM CORP (CA)

Application No.: US2003-0364983 Applic. Date: 2003-02- 12

Abstract: Solutions and aerosols of metal-containing compounds are disclosed. Methods of preparing and using the solutions and aerosols, particularly in the treatment of a subject having a condition, are also disclosed. The metal-containing material can be, for example, an antimicrobial material, an antibacterial material, an anti-inflammatory material, an anti-fungal material, an anti- viral material, an anti-cancer material, a pro-apoptosis material, and/or an MMP modulating material. In certain embodiments, the metal-containing material is an atomically disordered, silver-containing material.

Priority: US2003-0364983 Applic. Date: 2003-02-12; US2002-0277673 Applic. Date: 2002-10-22; US2001-0916757 Applic. Date: 2001-07-27; US2001-0840637 Applic. Date: 2001-04-23; US2000 -0628735 Applic. Date: 2000-07-27; US2002-0159587 Applic. Date: 2002-05-30; US2002-0128208 Applic. Date: 2002-04-23; US2002-0131568 Applic. Date: 2002-04-23; US2002-0131511 Applic. Date: 2002-04-23; US2002-0131509 Applic. Date: 2002-04-23; US2001-0285884P Applic. Date: 2001-04- 23

Inventor: BURRELL ROBERT E (CA); WRIGHT JOHN B (US); LAM KAN (US); YIN HUA QING (CA); NAYLOR ANTONY G (CA); MOXHAM PETER H (CA); GILLIS SCOTT H (US); SCHECHTER PAUL (US); SCHECHTER PAUL (US)


Patent No.: US 7115282 B2 Issued: 2006-10-03
Publication No.: US20030198652A1 Published: 2003-10- 23

Title: Multi component controlled release system for anhydrous cosmetic compositions

Applicant: SALVONA IP LLC (US)

Application No.: US2002-0124207 Applic. Date: 2002-04-17

Abstract: The present invention relates to an improved controlled release system that can be incorporated into anhydrous cosmetic formulations and can encapsulate different types of fragrances, flavors, active ingredients, or combinations of fragrances, flavors, and various active ingredients. The controlled delivery system of the present invention is substantially free-flowing powder formed of solid hydrophobic nano-spheres that are encapsulated in a moisture sensitive micro-spheres. The fragrances, flavors, and active ingredients encapsulated in the nano-spheres can be the same or different from those encapsulated in the micro-sphere.; The encapsulation of one or more fragrances, flavors or active agents in the various components of the system, such as nano-spheres and micro-spheres, provides odor or flavor transition (change in odor character or change in flavor character) during the use of the product, in response to moisture, such as wetting the lips, perspiration, and the like. The incorporation of the controlled release system of the present invention into anhydrous cosmetic formulations was found to provide moisture triggered release, as well as prolonged release of the fragrances, flavors, and active ingredients that are encapsulated in the solid hydrophobic nano-spheres over an extended period of time.

Priority: US2002- 0124207 Applic. Date: 2002-04-17

Inventor: SHEFER ADI (US); SHEFER SHMUEL DAVID (US); DAVID SHEFER SHMUEL (US)


Patent No.: US 7125858 B2 Issued: 2006-10-24
Publication No.: US20030176381A1 Published: 2003-09-18

Title: Hyaluronic acid in the treatment of cancer

Applicant: BIONICHE LIFE SCIENCES INC (CA)

Application No.: US2002-0168327 Applic. Date: 2002 -08-29

Abstract: The present invention relates to a composition and method comprising purified HA, a second anti-neoplastic agent and a pharmaceutically acceptable carrier, wherein the purified HA and the second anti-neoplastic agent are administered to a mammal having cancer in an amount effective to treat the cancer.

Priority: US2002-0168327 Applic. Date: 2002-08-29; US1999 -0173375P Applic. Date: 1999-12-28; WO2000-CA01562 Applic. Date: 2000-12-28

Inventor: FILION MARIO C (CA); PHILLIPS NIGEL C (CA)


Patent No.: US 7137970 B1 Issued: 2006-11- 21

Title: Test method for assessing irritation of skin

Applicant: PROCTER & GAMBLE (US)

Application No.: US2006-0337900 Applic. Date: 2006-01- 23

Abstract: Test methods for assessing irritation of portions of skin and/or assessing inhibition and/or reduction of such irritation are provided.

Priority: US2006-0337900 Applic. Date: 2006-01-23

Inventor: FARAGE MIRANDA AREF (US)


Patent No.: US 7138108 B2 Issued: 2006-11-21
Publication No.: US20040037791A1 Published: 2004-02-26

Title: Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes

Applicant: OREAL (FR)

Application No.: US2003-0460195 Applic. Date: 2003-06-13

Abstract: Novel (phenylsulfonyl)acrylonitrile siloxanes/silanes, and cosmetic/dermatological sunscreen compositions comprised thereof, are well suited for UV-A photoprotecting the skin and/or the hair against the damaging effects of solar radiation.

Priority: US2003-0460195 Applic. Date: 2003-06-13; FR2002-0007287 Applic. Date: 2002-06-13; US2002-0394659P Applic. Date: 2002-07-10

Inventor: RICHARD HERVE (FR); BRETON PHILIPPE (FR)


Patent No.: US 7147673 B2 Issued: 2006-12-12
Publication No.: US20050005369A1 Published: 2005-01-13

Title: Composition for dyeing human keratin materials, comprising at least one fluorescent dye and at least one insoluble polyorganosiloxane conditioning polymer, process therefor and use thereof

Applicant: OREAL (FR)

Application No.: US2004-0814334 Applic. Date: 2004-04-01

Abstract: Disclosed herein is a composition comprising at least one fluorescent dye and at least one insoluble polyorganosiloxane conditioning polymer, processes using this composition, and a device. Further disclosed herein is the use of compositions comprising at least one fluorescent dye and at least one insoluble polyorganosiloxane conditioning polymer, for dyeing human keratin materials, for example artificially dyed and/or pigmented hair and dark skin, with a tightening effect.

Priority: US2004-0814334 Applic. Date: 2004-04-01; FR2003-0004033 Applic. Date: 2003-04-01; US2003-0468079P Applic. Date: 2003-05-06

Inventor: PLOS GREGORY (FR); SAMAIN HENRI (FR)


Patent No.: US 7147841 B2 Issued: 2006-12-12
Publication No.: US20030235540A1 Published: 2003-12- 25

Title: Formulation of UV absorbers by incorporation in solid lipid nanoparticles

Applicant: CIBA SC HOLDING AG (US)

Application No.: US2003- 0460945 Applic. Date: 2003-06-13

Abstract: Solid lipid nanoparticle compositions containing (a) 1 to 40% by weight of an oil-soluble UV absorber, (b) 20 to 98.9% by weight of a solid lipid, (c) 0.1 to 20% by weight of an emulsifier and (d) 0 to 40% by weight of a liquid lipid or a liquid oil-miscible UV absorber The compositions according to the invention enhance the solubility behaviour of oil-soluble UV filters in cosmetic formulations and thereby also improve their effectiveness.

Priority: EP2002-0405497 Applic. Date: 2002-06-17

Inventor: HERZOG BERND (DE)


Patent No.: US 7150764 B2 Issued: 2006-12-19
Publication No.: US20050076457A1 Published: 2005-04- 14

Title: Composition for dyeing a human keratin material, comprising at least one fluorescent dye and at least one insoluble conditioning agent, process thereof, use thereof, and devices thereof

Applicant: OREAL (FR)

Application No.: US2004-0814337 Applic. Date: 2004-04-01

Abstract: A composition comprising at least one fluorescent dye and at least one insoluble conditioning agent; and processes and multicompartment kits comprising the composition. This disclosure also relates to the use of this composition for dyeing a human keratin material, and, for example, artificially dyed or pigmented hair and/or dark skin, with a lightening effect.

Priority: US2004-0814337 Applic. Date: 2004-04-01; FR2003-0004021 Applic. Date: 2003-04-01; US2003-0468063P Applic. Date: 2003-05-06

Inventor: PLOS GREGORY (FR); SAMAIN HENRI (FR)


Patent No.: US 7151872 B1 Issued: 2006-12-19

Title: Method, system and module for monitoring a power generating system

Applicant: GEN ELECTRIC (US)

Application No.: US2005- 0284595 Applic. Date: 2005-11-22

Abstract: A sensing module positioned about an optical fiber cable having a long axis. The optical fiber includes a core that transmits light through the optical fiber cable. The sensing module includes a first short-period fiber grating positioned about the core. A second short-period fiber grating is positioned about the core and at a distance along the long axis with respect to the first short-period fiber grating. At least one of a long-aperiod fiber grating and a long-period fiber grating is positioned between the first short-period fiber grating and the second short-period fiber grating. A fiber cladding is positioned around the long-period grating and/or the long-aperiod grating of the sensing module. A sensing skin is positioned about the fiber cladding and includes a chemical gas active material.

Priority: US2005-0284595 Applic. Date: 2005-11-22

Inventor: XIA HUA (US); DENG KUNG-LI JUSTIN (US); MCCARTHY KEVIN THOMAS (US); TAWARE AVINASH VINAYAK (US)


Patent No.: US 7153494 B2 Issued: 2006-12-26
Publication No.: US20040091434A1 Published: 2004-05-13

Title: Dibenzoylmethane sunscreen compositions photostabilized with amphiphilic block copolymers

Applicant: OREAL (FR)

Application No.: US2003-0688937 Applic. Date: 2003-10-21

Abstract: Topically applicable photostable sunscreen/photoprotective compositions contain at least one dibenzoylmethane UV-sunscreen and an effective photostabilizing amount therefor of at least one amphiphilic block copolymer which comprises at least one nonionic hydrophilic polymer block and at least one hydrophobic polymer block, formulated into a topically applicable, cosmetically acceptable medium therefor.

Priority: US2003-0688937 Applic. Date: 2003-10-21; FR2002-0013103 Applic. Date: 2002-10-21; US2003-0452541P Applic. Date: 2003-03-07

Inventor: CHODOROWSKI-KIMMES SANDRINE (FR); QUINN FRANCIS XAVIER (FR); SIMONNET JEAN-THIERRY (FR)


Patent No.: US 7166274 B2 Issued: 2007-01-23
Publication No.: US20040047820A1 Published: 2004-03-11

Title: Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds

Applicant: OREAL (FR)

Application No.: US2003-0463328 Applic. Date: 2003-06-18

Abstract: Topically applicable high SPF cosmetic/dermatological UV-screening compositions suited for the photoprotection of the skin and/or hair, comprise (a) particulates of at least one insoluble organic UV-screening agent having a particle size ranging from 10 nm to 5 mum, as a first screening agent, and (b) at least one 4,4-diarylbutadiene compound, as a second screening agent, formulated into a topically applicable, cosmetically/dermatologically acceptable vehicle therefor.

Priority: FR2000-0016520 Applic. Date: 2000-12-18; WO2001-FR03637 Applic. Date: 2001-11-20

Inventor: CANDAU DIDIER (FR)


Patent No.: US 7172753 B2 Issued: 2007-02-06
Publication No.: US20040028626A1 Published: 2004-02- 12

Title: Photoprotective UV-screening compositions comprising triazine/dibenzoylmethane/diarylbutadiene compounds

Applicant: OREAL (FR)

Application No.: US2003-0463432 Applic. Date: 2003-06-18

Abstract: Topically applicable, photostable cosmetic/dermatological UV-screening compositions suited for photoprotecting the skin and the hair, comprise (a) at least one UV-screening dibenzoylmethane compound, (b) at least one UV-screening 1,3,5-triazine compound that is photosensitive in the presence of a dibenzoylmethane compound, and (c) a 1,3,5-triazine photostabilizing amount of at least one 4,4- diarylbutadiene compound, formulated into a topically applicable, cosmetically/dermatologically acceptable support therefor; the weight ratio of the 4,4-diarylbutadiene compound(s) to the dibenzoylmethane compound(s) is characteristically greater than 2.5 and the subject compositions are advantageously devoid of any cinnamate sunscreen.

Priority: FR2000-0016517 Applic. Date: 2000-12-18; WO2001-FR03639 Applic. Date: 2001-11-20

Inventor: CANDAU DIDIER (FR)


Patent No.: US 7175834 B2 Issued: 2007-02-13
Publication No.: US20050186160A1 Published: 2005-08-25

Title: Sunscreen composition with enhanced SPF and water resistant properties

Applicant: ENGELHARD CORP (US)

Application No.: US2005-0114668 Applic. Date: 2005-04- 26

Abstract: The present invention relates to a sunscreen formulation which exhibits superior ultraviolet protection and water resistance than prior art sunscreen compositions. The sunscreen formulation comprises (a) a dispersion comprising a sunscreen active agent and (b) a base composition comprising a rheological modifying agent and water. The sunscreen formulation is substantially free of surfactants. According to a preferred embodiment, the sunscreen active agent is ethylhexylmethoxycinnamate, butylmethoxydibenzoylmethane, or a combination thereof. The sunscreen formulation preferably comprises a phosphorylated starch derivative as a rheological modifying agent. Another embodiment of the present invention is a method of protecting skin or hair from ultraviolet radiation by applying an effective amount of the sunscreen formulation of the present invention to the skin or hair.

Priority: US2005-0114668 Applic. Date: 2005-04-26; US2003-0332393 Applic. Date: 2003-04-29; WO2001-US21588 Applic. Date: 2001-07-09; US2000-0216573P Applic. Date: 2000-07- 07

Inventor: AUST DUNCAN T (US); WILMOTT JAMES M (US); HAYWARD JAMES A (US)


Patent No.: US 7179477 B2 Issued: 2007-02-20
Publication No.: US20050037038A1 Published: 2005-02-17

Title: Cosmetic Dermabrasion Treatment System

Application No.: US2003-0604781 Applic. Date: 2003-08-15

Abstract: The present invention provides a complementary three-step dermabrasion system that provides treatment for skin conditions such as acne scars, wound scars, and other visually unappealing skin disfigurements, which constitutes the following, (1) Dermal Resurfacing with an adhesive composition, (2) Dermal Polishing with a polishing composition, and (3) Dermal Regeneration with a collagen-building and cell-proliferative composition.

Priority: US2003-0604781 Applic. Date: 2003-08-15

Inventor: GUPTA SHYAM K (US)


Patent No.: US 7181266 B2 Issued: 2007-02- 20
Publication No.: US20050020923A1 Published: 2005-01-27

Title: Materials and methods for near-infrared and infrared lymph node mapping

Applicant: BETH ISREAL DEACONESS MEDICAL (US)

Application No.: US2004-0772425 Applic. Date: 2004- 02-06

Abstract: A lymphatic system can be imaged with emissive semiconductor nanocrystals, for example, in the near infrared.

Priority: US2004-0772425 Applic. Date: 2004-02-06; US2003-0451246P Applic. Date: 2003-03-04

Inventor: FRANGIONI JOHN V (US); BAWENDI MOUNGI G (US); KIM SUNGJEE (US); LIM YONG TAIK (KR)


Patent No.: US 7182938 B2 Issued: 2007-02-27
Publication No.: US20050255057A1 Published: 2005-11-17

Title: Cosmetic formulations comprising ZnO nanoparticles

Applicant: BASF AG (DE)

Application No.: US2005-0074760 Applic. Date: 2005-03-09

Abstract: The present invention relates to the formation of surface treated zinc oxide and titania particles, and in particular zinc oxide and titania nanoparticles, with a siloxane star-graft copolymer coating, comprising a looped and/or linear polymeric structure on a star-graft copolymer coating, on a particle surface to control the interfacial surface interactions between the particle and the oil phase of the cosmetic skin formulation.

Priority: US2005-0074760 Applic. Date: 2005-03-09; US2004-0592133P Applic. Date: 2004-07-30; US2004-0559857P Applic. Date: 2004-04-06

Inventor: ANDRE VALERIE (DE); BROTZMAN JR RICHARD W (US); BROTZMAN RICHARD W JR (US)


Patent No.: US 7182963 B2 Issued: 2007-02-27
Publication No.: US20040254245A1 Published: 2004-12-16

Title: Cosmetic and dermopharmaceutical compositions for skin prone to acne

Applicant: SEDERMA (FR)

Application No.: US2004-0817670 Applic. Date: 2004-04-02

Abstract: The invention relates to the use of an extract of olive leaves (Olea europaea) which is titrated in oleanolic acid and which may or may not be associated with a Larrea divaricata extract which is titrated in nordihydroguaiaretic acid (NDGA). Said products are intended for all types of cosmetic and dermopharmaceutical compositions for all forms of skin care, for moisturizing and anti-inflammatory purposes and, in particular, for the prevention and treatment of skin prone to acne.

Priority: FR2001-0012802 Applic. Date: 2001-10-03; WO2002-FR03344 Applic. Date: 2002-10-01

Inventor: LINTNER KARL (FR)


Patent No.: US 7183315 B2 Issued: 2007-02-27
Publication No.: US20040254366A1 Published: 2004-12-16

Title: Silver salts of sucrose- octasulphate

Applicant: INTERALIA S R L (IT)

Application No.: US2004-0492342 Applic. Date: 2004-04-09

Abstract: The described invention relates to the new compound "sucrose-octasulphate salified with silver" usefully applicable in the prevention and cure of infections by micro-organisms of bacterial, fungal, viral and/or yeast origins and in the promotion of tissue repair. The silver salts of sucrose octasulphate, subject of the invention have in fact been shown to possess antimicrobial activities even higher than that of known silver compounds. These properties therefore make them particularly suitable for use in different pathological or paraphysiological conditions of the skin, of the epithelia and of the mucosa both intact and lesioned.

Priority: WO2002-EP11627 Applic. Date: 2002-10-17; IT2001-MI02188 Applic. Date: 2001-10-19

Inventor: CALDERINI GABRIELLA (IT); PROSDOCIMI MARCO (IT); ANTICO CLAUDIO (IT); MIGLIERINI GIULIANA (IT); CASADEI MASSARI DANILO (IT); MIGLIERNI GIULIANA (IT); CASADEI MESSARI DANILO (IT)


Patent No.: US 7183337 B1 Issued: 2007-02-27
Publication No.: US20070032572A1 Published: 2007-02- 08

Title: OPTICALLY CLEAR NANOCOMPOSITES AND PRODUCTS USING NANOSCALE FILLERS

Applicant: NANOPRODUCTS CORP (US)

Application No.: US2003-0426414 Applic. Date: 2003-04-30

Abstract: Methods for preparing nanocomposites that enable films with optical clarity, wear resistance and superior functional performance. Nanofillers and a substance having a polymer are mixed. Both low-loaded and highly-loaded nanocomposites are included. Nanocomposite films may be coated on substrates.

Priority: US2003-0426414 Applic. Date: 2003-04-30; US2001-0790036 Applic. Date: 2001-02-20; US1998-0083893 Applic. Date: 1998-05-22; US1996 -0739257 Applic. Date: 1996-10-30; US1996-0730661 Applic. Date: 1996-10-11; US1996-0706819 Applic. Date: 1996-09-03; US2001-0753806 Applic. Date: 2001-01-03; US1998-0074534 Applic. Date: 1998-05-07; US1996-0707341 Applic. Date: 1996-09-03; US1997-0049077P Applic. Date: 1997-06-09; US1997-0069935P Applic. Date: 1997-12-17; US1998-0079225P Applic. Date: 1998-03-24

Inventor: YADAV TAPESH (US); KOSTELECKY CLAYTON (US)


Patent No.: US 7184614 B2 Issued: 2007-02-27
Publication No.: US20040036975A1 Published: 2004-02-26

Title: Method and apparatus for improving safety during exposure to a monochromatic light source

Applicant: INOLASE 2002 LTD (IL)

Application No.: US2003-0614672 Applic. Date: 2003-07-07

Abstract: A method and apparatus are disclosed for improving bodily safety during exposure to an eye hazardous monochromatic treatment light source by diverging the light, such as with a diffusing unit attached to the light source distal end so that the radiance of the light exiting the distal end is an eye safe level. At a first position of the light source distal end substantially in contact with an outer surface of a target, the energy density of an exit beam from the distal end is suitable for effecting a desired treatment, and at a second non-contact position of the distal end the exit beam energy density is significantly less than a value suitable for effecting the treatment. In an additional embodiment, the diverging or diffusing unit has a device for evacuating vapors or particles from the target.

Priority: IL2001-0147009 Applic. Date: 2001-12-10; IL2002-0150094 Applic. Date: 2002-06-06; WO2002-IL00635 Applic. Date: 2002-08-02

Inventor: SLATKINE MICHAEL (IL)


Patent No.: US 7186278 B2 Issued: 2007-03-06
Publication No.: US20040256598A1 Published: 2004-12- 23

Title: Composition for dyeing human keratin materials, comprising at least one fluorescent dye and at least one compound comprising an acid functional group and processes therefor

Applicant: OREAL (FR)

Application No.: US2004-0814430 Applic. Date: 2004-04-01

Abstract: The present disclosure relates to compositions comprising at least one soluble fluorescent dye and at least one compound comprising an acid functional group, and to processes using this composition. It likewise relates to a method of using compositions comprising, in a cosmetically acceptable medium, at least one soluble fluorescent dye and at least one compound comprising an acid functional group for dyeing human keratin materials, such as artificially dyed and/or pigmented hair and dark skin, with a lightening effect.

Priority: US2004-0814430 Applic. Date: 2004-04-01; FR2003-0004029 Applic. Date: 2003-04-01; US2003-0468078P Applic. Date: 2003-05- 06

Inventor: PLOS GREGORY (FR); GOURLAOUEN LUC (FR)


Patent No.: US 7192454 B2 Issued: 2007-03-20
Publication No.: US20050098763A1 Published: 2005-05-12

Title: Composition for dyeing human keratin materials, comprising a fluorescent dye and a particular sequestering agent, process therefor and use thereof

Applicant: OREAL (FR)

Application No.: US2004-0814585 Applic. Date: 2004-04-01

Abstract: The invention relates to a composition comprising at least one fluorescent dye and at least one particular sequestering agent, and also to processes and a device for using these compositions. The invention similarly relates to the use of a composition comprising at least one particular fluorescent dye and at least one particular sequestering agent, to dye with a lightening effect human keratin materials and more particularly artificially dyed or pigmented hair, and colored skin.

Priority: US2004-0814585 Applic. Date: 2004-04-01; US2003-0468081P Applic. Date: 2003-05-06; FR2003-0004024 Applic. Date: 2003-04- 01

Inventor: PLOS GREGORY (FR); GOURLAOUEN LUC (FR)


Patent No.: US 7195651 B2 Issued: 2007-03-27
Publication No.: US20040258641A1 Published: 2004-12-23

Title: Cosmetic composition for dyeing human keratin materials, comprising at least one fluorescent dye and at least one cationic polymer, and a dyeing process therefor

Applicant: OREAL (FR)

Application No.: US2004-0814335 Applic. Date: 2004-04-01

Abstract: The present disclosure relates to a cosmetic composition comprising at least one fluorescent dye comprising at least one fluorescent compound, and at least one cationic polymer with a charge density of at least 1 meq/g; processes that incorporate this cosmetic composition and to a kit comprising this cosmetic composition. The present disclosure also relates to the process for dyeing human keratin materials, including artificially dyed or pigmented hair and dark skin, with a lightening effect, comprising applying to the keratin materials a cosmetic composition comprising at least one fluorescent dye comprising at least one fluorescent compound and at least one cationic polymer with a charge density of at least 1 meq/g.

Priority: US2004-0814335 Applic. Date: 2004-04-01; FR2003-0004026 Applic. Date: 2003-04-01; US2003-0467548P Applic. Date: 2003-05-05

Inventor: PLOS GREGORY (FR); SAMAIN HENRI (FR)


Patent No.: US 7195754 B1 Issued: 2007-03-27

Title: Nanotube based sunscreen

Applicant: EIKOS INC (US)

Application No.: US2003-0373181 Applic. Date: 2003-02- 26

Abstract: This invention relates generally to the incorporation of carbon nanotubes into compositions for protection against damage from ultraviolet radiation. In particular, the invention is directed to sunscreen compositions and methods for the preparation of sunscreen compositions.

Priority: US2003-0373181 Applic. Date: 2003-02-26; US2002-0359362P Applic. Date: 2002-02-26

Inventor: GLATKOWSKI PAUL J (US); PICHE JOSEPH W (US); CONROY JEFFREY L (US); BOLDUC ROY (US); LABLANC PIERRE (US)


Patent No.: US 7198606 B2 Issued: 2007-04-03
Publication No.: US20030199893A1 Published: 2003-10-23

Title: Method and apparatus for a multi-use body fluid sampling device with analyte sensing

Applicant: PELIKAN TECHNOLOGIES INC (US)

Application No.: US2002-0323624 Applic. Date: 2002-12- 18

Abstract: A device for use with a penetrating member driver to penetrate tissue is provided. A plurality of penetrating members are coupled to a single cartridge and are operatively couplable to the penetrating member driver. The penetrating members are movable to extend radially outward from the cartridge to penetrate tissue. A plurality of analyte sensors are coupled to the single cartridge and are positioned on the cartridge to receive body fluid from a wound in the tissue created by the penetrating member.

Priority: US2002-0323624 Applic. Date: 2002-12-18; US2002- 0127395 Applic. Date: 2002-04-19; US2002-0393706P Applic. Date: 2002-07-01; US2002-0393707P Applic. Date: 2002-07-01; US2002-0422988P Applic. Date: 2002-11-01; US2002-0424429P Applic. Date: 2002-11-06; US2002-0428084P Applic. Date: 2002-11-20

Inventor: BOECKER DIRK (US); FREEMAN DOMINIQUE M (US)


Patent No.: US 7198650 B2 Issued: 2007-04-03
Publication No.: US20050005371A1 Published: 2005-01- 13

Title: Method of dyeing human keratin materials with a lightening effect with compositions comprising at least one fluorescent dye and at least one amphoteric or nonionic surfactant, composition thereof, process thereof, and device therefor

Applicant: OREAL (FR)

Application No.: US2004-0814338 Applic. Date: 2004-04-01

Abstract: The present disclosure relates to a method of dyeing human keratin materials with a lightening effect with a composition comprising, in a cosmetically acceptable medium, at least one fluorescent dye that is soluble in the cosmetically acceptable medium and at least one surfactant chosen from amphoteric surfactants and nonionic surfactants. The present disclosure also relates to compositions comprising at least one particular fluorescent dye that is soluble in the cosmetically acceptable medium and at least one surfactant chosen from amphoteric surfactants and nonionic surfactants, and also to processes using these compositions, and devices for these compositions.

Priority: US2004-0814338 Applic. Date: 2004-04-01; FR2003-0004034 Applic. Date: 2003-04-01; US2003-0468106P Applic. Date: 2003-05- 06

Inventor: POURILLE-GRETHEN CHRYSTEL (FR); PLOS GREGORY (FR)


Patent No.: US 7201925 B2 Issued: 2007-04- 10
Publication No.: US20040176312A1 Published: 2004-09-09

Title: Treatment of ungual and subungual diseases

Applicant: NUERYST PHARMACEUTICALS CORP (CA)

Application No.: US2004-0770132 Applic. Date: 2004-02-02

Abstract: The treatment of ungual and subungual diseases is disclosed.

Priority: US2004-0770132 Applic. Date: 2004-02-02; US2002-0131511 Applic. Date: 2002-04-23; US2002-0131568 Applic. Date: 2002- 04-23; US2002-0159587 Applic. Date: 2002-05-30; US2002-0128208 Applic. Date: 2002-04-23; US2002- 0131509 Applic. Date: 2002-04-23; US2002-0277673 Applic. Date: 2002-10-22; US2002-0277356 Applic. Date: 2002-10-22; US2002-0277298 Applic. Date: 2002-10-22; US2002-0277362 Applic. Date: 2002-10-22; US2002-0277358 Applic. Date: 2002-10-22; US2002-0277320 Applic. Date: 2002-10-22; US2003-0690774 Applic. Date: 2003-10-22; US2003-0690724 Applic. Date: 2003-10-22; US2003-0690715 Applic. Date: 2003- 10-22

Inventor: GILLIS SCOTT H (US)


Patent No.: US 7202418 B2 Issued: 2007-04-10
Publication No.: US20050199415A1 Published: 2005-09-15

Title: Flame retardant and smoke suppressant composite high performance support-separators and conduit tubes

Applicant: CABLE COMPONENTS GROUP LLC (US)

Application No.: US2005-0030436 Applic. Date: 2005 -01-06

Abstract: The present invention includes a high performance communications cable exhibiting reduced cross-talk of any form between transmission media that includes one or more core support-separators having various shaped profiles which define a clearance to maintain a spacing between transmission media or transmission media pairs. The core may be formed of a conductive or insulative material to further reduce cross-talk and improve other electrical properties as well as reduce flame and smoke spread. The cable and separators are comprised of principally polymer blends that include olefin and/or fluoropolymer and/or chlorofluoropolymer based resins with and without inorganic additive such as nano-clay composites.; These unique blends offer both flame and smoke suppression while maintaining the characteristics necessary to improve electrical performance and allow for severe cost reduction over conventional separators. The specially shaped core support-separators can be either interior to the cable jacket or be employed singularly without the benefit of a jacket and extend along the longitudinal length of the communications cable. Alternatively, with no jacket for cable completion, a portion of the separator wherein a thin layer of material can act as a type of skin for future mechanical protection is provided. The specially shaped core support-separator has both a central region as well as a plurality of shaped sections that extend outward from the central region that are either solid or partially solid, foamed or foamed with a solid skin surface.; In addition, the invention includes the optional incorporation of hollow ducts that can be used to provide optical or metal conductor media either before, during, or after installation of the cable primarily by gas driven means.

Priority: US2005-0030436 Applic. Date: 2005-01-06; US2004-0534646P Applic. Date: 2004-01-07

Inventor: GLEW CHARLES A (US)


Patent No.: US 7204860 B2 Issued: 2007-04-17
Publication No.: US20050008594A1 Published: 2005-01-13

Title: Composition for dyeing human keratin materials, comprising at least one fluorescent dye and at least one polyol, process therefor and use thereof

Applicant: OREAL (FR)

Application No.: US2004-0814300 Applic. Date: 2004-04-01

Abstract: Disclosed herein are compositions comprising at least one fluorescent dye and at least one polyol, processes using this composition and a device therefor. Further disclosed herein is the use of a composition for dyeing a human keratin material, such as artificially dyed or pigmented hair and dark skin, with a lightening effect, comprising at least one fluorescent dye and at least one polyol.

Priority: US2004-0814300 Applic. Date: 2004-04-01; FR2003- 0004030 Applic. Date: 2003-04-01; US2003-0468086P Applic. Date: 2003-05-06

Inventor: PLOS GREGORY (FR); GOURLAOUEN LUC (FR)


Patent No.: US 7208018 B2 Issued: 2007-04-24
Publication No.: US20050031562A1 Published: 2005-02-10

Title: Composition for dyeing human keratin materials, comprising at least one fluorescent dye and at least one associative polymer, process therefor and use thereof

Applicant: OREAL (FR)

Application No.: US2004-0814305 Applic. Date: 2004-04-01

Abstract: Disclosed herein are compositions comprising at least one fluorescent dye and at least one particular associative polymer, processes using this composition, and a device therefor. Further disclosed herein is the use of a composition comprising at least one fluorescent dye and at least one particular associative polymer for dyeing a human keratin material, such as artificially dyed or pigmented hair and dark skin, with a lightening effect.

Priority: US2004-0814305 Applic. Date: 2004-04-01; FR2003-0004035 Applic. Date: 2003-04-01; US2003-0468080P Applic. Date: 2003-05-06

Inventor: GOURLAOUEN LUC (FR); SAMAIN HENRI (FR)


Patent No.: US 7208142 B2 Issued: 2007-04-24
Publication No.: US20020143203A1 Published: 2002-10- 03

Title: Indanylidene compounds

Applicant: SYMRISE GMBH & CO KG (DE)

Application No.: US2001-0008044 Applic. Date: 2001-11-08

Abstract: Novel indanylidene compounds can be used as UV-A filters in cosmetic compositions for protecting skin and hair and for technical applications.

Priority: DE2000-1055940 Applic. Date: 2000-11- 10

Inventor: KOCH OSKAR (DE); DILK ERICH (DE); LANGNER ROLAND (DE); JOHNCOCK WILLIAM (DE)


Patent No.: US 7208429 B2 Issued: 2007-04-24
Publication No.: US20060121278A1 Published: 2006-06- 08

Title: Fibrous structures comprising a nonoparticle additive

Applicant: PROCTER & GAMBLE (US)

Application No.: US2004-0001891 Applic. Date: 2004-12- 02

Abstract: Fibrous structures having an additive, more particularly finished fibrous structures having a nanoparticle solid additive, and/or sanitary tissue products including such finished fibrous structures, are provided.

Priority: US2004-0001891 Applic. Date: 2004-12- 02

Inventor: VINSON KENNETH DOUGLAS (US); PRODOEHL MICHAEL SCOTT (US); VINSON KENNETH D (US); PRODOEHL MICHAEL S (US)


Patent No.: US 7208460 B2 Issued: 2007-04-24
Publication No.: US20050065047A1 Published: 2005-03-24

Title: Multi component controlled delivery system for soap bars

Applicant: SALVONA IP LLC (US)

Application No.: US2004-0948971 Applic. Date: 2004-09-24

Abstract: The present invention relates to an improved controlled delivery system that can be incorporated in soap bars to enhance deposition of active ingredients and sensory markers onto skin. The carrier system also provides controlled release or prolonged release of these actives from the skin over an extended period of time. The controlled delivery system of the present invention comprises substantially free-flowing, powder formed of solid hydrophobic, positively charged, nanospheres of encapsulated active ingredients, that are encapsulated in moisture sensitive microspheres. The high cationic charge density of the nanosphere improves deposition of active ingredients onto skin.; The high cationic charge density on the nanosphere surface is created by incorporating a cationic conditioning agent into the solid hydrophobic matrix of the nanospheres, by incorporating a cationic charge "booster" in the moisture sensitive microsphere matrix, or by using a cationic conditioning agent in the nanosphere matrix in conjunction with a cationic charge "booster" in the microsphere matrix. The invention also pertains to soap products comprising the controlled release system of the present invention.

Priority: US2004-0948971 Applic. Date: 2004-09-24; US2002-0286143 Applic. Date: 2002-11-01; US2002-0133833 Applic. Date: 2002-04-26

Inventor: SHEFER ADI (US); SHEFER SAMUEL (US)


Patent No.: US 7217267 B2 Issued: 2007-05- 15
Publication No.: US20050049657A1 Published: 2005-03-03

Title: Hair treatment method

Application No.: US2004-0773621 Applic. Date: 2004-02- 06

Abstract: A hair treatment device includes a generator of electromagnetic radiation and optical guide components operatively connected to the generator so as to direct electromagnetic radiation from the generator away from entering a skin surface and in a direction substantially parallel to the skin surface, to impinge on hair fibers protruding from the skin surface. A control unit is connected to the generator for controlling the generator to produce the electromagnetic radiation in bursts of light pulses each having a predetermined number of pulses of light for treating the hair fibers protruding from the skin surface.

Priority: US2004-0773621 Applic. Date: 2004-02- 06; US2003-0647948 Applic. Date: 2003-08-26

Inventor: JAY HARVEY (US)


Patent No.: US 7217821 B2 Issued: 2007-05- 15
Publication No.: US20040234464A1 Published: 2004-11-25

Title: Photoprotective cosmetic compositions comprising para-aminobenzalmalonate-substituted s-triazine compounds

Applicant: OREAL (FR)

Application No.: US2004-0829440 Applic. Date: 2004-04-22

Abstract: Cosmetic/dermatological sunscreen compositions, suited for photoprotecting, e.g., the skin, lips, scalp and/or hair against the damaging effects of UV-radiation, contain thus effective amounts of at least one novel s-triazine compound tri-substituted with para- aminobenzalmalonate substituents.

Priority: US2004-0829440 Applic. Date: 2004-04-22; FR2003-0004922 Applic. Date: 2003-04-22; US2003-0483651P Applic. Date: 2003-07- 01

Inventor: RICHARD HERVE (FR); HERVE RICHARD (FR)


Patent No.: US 7220438 B2 Issued: 2007-05-22
Publication No.: US20040126442A1 Published: 2004-07-01

Title: Pharmacological activities of Curcuma longa extracts

Applicant: ASAC COMPANIA DE BIOTECNOLOGIA (ES); ASCA COMPANIA DE BIOTECNOLOGIA (US)

Application No.: US2003-0684452 Applic. Date: 2003-10- 15

Abstract: This invention concerns to a topical pharmaceutical composition comprising an water soluble Curcuma extract, and suitable excipients for said topical administration; the process for obtaining said pharmaceutical compositions; the use of different Curcuma extracts as photosensitizing agents for the treatment of proliferative diseases; and the use of Curcuma extract or curcuminoids in combination with a radiation for the treatment of proliferative diseases on eukaryote cells.

Priority: US2003-0684452 Applic. Date: 2003-10-15; ES1999-0002364 Applic. Date: 1999-09-23; US2002-0856035 Applic. Date: 2002-02-19; WO2000-ES00354 Applic. Date: 2000-09- 21

Inventor: QUINTANILLA ALMAGRO ELISEO (ES); RAMIREZ BOSCA ANA (ES); BERND AUGUST (ES); PARDO ZAPATA JOSE (ES); D DOT OVER IAEZ ALPERI JOAQUIN (ES); PAMIES MIRA DAVID (ES); CARRION GUTIERREZ MIGUEL ANGEL (ES); SEMPERE ORTELLS JOSE MIGUEL (ES); DIAZ ALPERI JOAQUIN (ES)


Patent No.: US 7223384 B1 Issued: 2007-05-29

Title: Cosmetic compositions comprising at least one silicone copolymer and at least one additional silicone, and uses thereof

Applicant: OREAL (FR)

Application No.: US2000-0692749 Applic. Date: 2000-10-20

Abstract: Cosmetic compositions comprising, in a cosmetically acceptable medium, at least one silicone copolymer with a dynamic viscosity ranging from 1x10[6] to 100x10[6] cP and at least one additional silicone. This combination can give cosmetic properties, such as at least one of smoothness, lightness, and softness, without the phenomenon of regressing keratin fibers. These compositions can be used for washing and/or conditioning a keratin material, such as the hair or the skin.

Priority: FR1999-0013096 Applic. Date: 1999-10-20

Inventor: DECOSTER SANDRINE (FR); DOUIN VERONIQUE (FR); BAILLY VIRGINIE (FR)


Patent No.: US 7228160 B2 Issued: 2007-06-05
Publication No.: US20040152187A1 Published: 2004-08- 05

Title: System, apparatus and method for inferring glucose levels within the peritoneum with implantable sensors

Applicant: SORENSON MEDICAL INC (US)

Application No.: US2003-0703152 Applic. Date: 2003-11-06

Abstract: A glucose sensor assembly useful in patient systems includes an oxygen sensor from which glucose levels in the vicinity of the peritoneal cavity may be inferred. The sensor assembly may be associated with electronics, such as any or all of a DC power supply, an LED source of blue light, a photoreceptor for red light, a CPU, and transceiver, by a direct percutaneous connection. Alternatively they may be associated transdermally with the sensor and some of the electronics being located subdurally. Insulin infusion means are contemplated to respond manually or mechanically to information from the sensors through the CPU. Mechanical response may be automatic. Infusion means may be located subdurally. It is contemplated that the present invention enable revitalization or replacement of fluorescing compounds and glucose oxidase within the sensor assembly.

Priority: US2003-0703152 Applic. Date: 2003-11-06; US2002- 0426266P Applic. Date: 2002-11-13

Inventor: HAIGHT LEVOY GOLDEN (US); GORDON KEVIN W (US); SORENSON JAMES L (US)


Patent No.: US 7229609 B2 Issued: 2007-06-12
Publication No.: US20050201957A1 Published: 2005-09-15

Title: Diarylbutadiene-substituted methyltrialkylsilanes and photoprotective compositions comprised thereof

Applicant: OREAL (FR)

Application No.: US2004-0995202 Applic. Date: 2004-11-24

Abstract: Novel 4,4- diarylbutadiene-substituted methyltrialkylsilanes having the structural formula (I): are useful sunscreens for UV-photoprotecting human skin against the damaging effects of UV-radiation, notably UV-A radiation.

Priority: US2004-0995202 Applic. Date: 2004-11-24; FR2003-0050899 Applic. Date: 2003-11-25; US2003-0526988P Applic. Date: 2003-12-05

Inventor: RICHARD HERVE (FR)


Patent No.: US 7229610 B2 Issued: 2007-06-12
Publication No.: US20050129636A1 Published: 2005-06- 16

Title: Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof

Applicant: OREAL (FR)

Application No.: US2004-0995226 Applic. Date: 2004-11-24

Abstract: Novel 4,4-diarylbutadiene- substituted diorganopolysiloxanes having the structural formulae (1) or (2): in which A is a radical of formula (3) below: are useful sunscreens for UV-photoprotecting human skin against the damaging effects of UV-radiation, notably UV-A radiation.

Priority: US2004-0995226 Applic. Date: 2004-11- 24; FR2003-0050900 Applic. Date: 2003-11-25; US2003-0526987P Applic. Date: 2003-12- 05

Inventor: RICHARD HERVE (FR)


Patent No.: US 7232605 B2 Issued: 2007-06-19
Publication No.: US20050013982A1 Published: 2005-01-20

Title: Hybrid natural-fiber composites with cellular skeletal structures

Applicant: UNIV MICHIGAN STATE (US)

Application No.: US2004-0892859 Applic. Date: 2004-07-16

Abstract: The present invention relates to composite structural members comprising polymers, natural and synthetic fibers, and nano-scale platelets arranged in two- or three-dimensional cellular skeletal structure; more particularly referring to a low-cost natural-fiber based structural member with material hybridization and material layout for improved behavior that leads to efficient structural beam and plate/panel components that can be used in a plurality of modular structures, resulting in lower cost and reduced environmental impact.

Priority: US2004-0892859 Applic. Date: 2004-07-16; US2003-0487971P Applic. Date: 2003-07-17

Inventor: BURGUENO RIGOBERTO (US); MOHANTY AMAR K (US); QUAGLIATA MARIO JOHN (US)


Patent No.: US 7235295 B2 Issued: 2007-06-26
Publication No.: US20050112349A1 Published: 2005-05-26

Title: Polymeric nanofibers for tissue engineering and drug delivery

Application No.: US2004-0938493 Applic. Date: 2004-09- 10

Abstract: Polymeric nanofibers have been developed which are useful in a variety of medical and other applications, such as filtration devices, medical prosthesis, scaffolds for tissue engineering, wound dressings, controlled drug delivery systems, cosmetic skin masks, and protective clothing. These can be formed of any of a variety of different polymers, either non-degradable or degradable. In a preferred embodiment demonstrated in the following examples, nanofibers are formed of biodegradable and non biodegradable polyphosphazenes, their blends with other polyphosphazenes or with organic, inorganic/organometallic polymers as well as composite nanofibers of polyphosphazenes with nanosized particles such as hydroxyapatites.

Priority: US2004-0938493 Applic. Date: 2004- 09-10; US2003-0501897P Applic. Date: 2003-09-10

Inventor: LAURENCIN CATO T (US); NAIR LAKSHMI SREEDHARAN (US); BHATTACHARYYA SUBHABRATA (US); ALLCOCK HARRY R (US); BENDER JARED D (US); BROWN PAUL W (US); GREISH YASER E (US)


Patent No.: US 7244442 B2 Issued: 2007-07-17
Publication No.: US20040053381A1 Published: 2004-03-18

Title: Method for making devices using polyhydroxyalkanoate having pyrogen removed

Applicant: METABOLIX INC (US)

Application No.: US2003-0642026 Applic. Date: 2003-08-15

Abstract: Polyhydroxyalkanoates (PHAs) from which pyrogen has been removed are provided for use in numerous biomedical applications. PHAs which have been chemically modified to enhance physical and/or chemical properties, for targeting or to modify biodegradability or clearance by the reticuloendothelial system (RES), are described. Methods for depyrogenating PHA polymers prepared by bacterial fermentation processes are also provided, wherein pyrogens are removed from the polymers without adversely impacting the polymers' inherent chemical structures and physical properties. PHAs with advantageous processing characteristics, including low melting points and/or solubility in non-toxic solvents, are also described.; PHAs are provided which are suitable for use in in vivo applications such as in tissue coatings, stents, sutures, tubing, bone and other prostheses, bone or tissue cements, tissue regeneration devices, wound dressings, drug delivery, and for diagnostic and prophylactic uses. Properties which are selected for include degradability, elasticity, inclusion of functional groups or derivatized groups, which can in turn be used to attach targeting agents, and bioadhesion.

Priority: US2003-0642026 Applic. Date: 2003-08-15; US2001-0819447 Applic. Date: 2001-03-28; US1998-0076198 Applic. Date: 1998-05-12; US1997-0065921P Applic. Date: 1997-11-17; US1997-0063501P Applic. Date: 1997-10-24; US1997-0054289P Applic. Date: 1997-07-31; US1997-0046211P Applic. Date: 1997-05-12; US1998-0090761 Applic. Date: 1998-06-04

Inventor: WILLIAMS SIMON F (US); MARTIN DAVID P (US); GERNGROSS TILLMAN (US); HOROWITZ DANIEL M (US)


Patent No.: US 7250064 B2 Issued: 2007-07- 31
Publication No.: US20050008593A1 Published: 2005-01-13

Title: Dye composition comprising at least one fluorescent dye and a non-associative thickening polymer for human keratin materials, process therefor, and method thereof

Applicant: OREAL (FR)

Application No.: US2004-0814236 Applic. Date: 2004-04-01

Abstract: The disclosure relates to a composition comprising at least one fluorescent dye and at least one non- associative thickening polymer, to processes using such a composition, and to devices comprising such a composition. The disclosure also relates to processes and methods for dyeing human keratin materials, for example artificially dyed or pigmented hair and dark skin, with a lightening effect, using compositions comprising at least one fluorescent dye and at least one non-associative thickening polymer.

Priority: US2004-0814236 Applic. Date: 2004-04-01; FR2003-0004028 Applic. Date: 2003-04-01; US2003-0468108P Applic. Date: 2003-05-06

Inventor: PLOS GREGORY (FR); GOURLAOUEN LUC (FR)


Patent No.: US 7255853 B2 Issued: 2007-08-14
Publication No.: US20040175337A1 Published: 2004-09- 09

Title: Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile

Applicant: OREAL (FR)

Application No.: US2004-0804128 Applic. Date: 2004-03-19

Abstract: Cosmetic compositions for topical use for protecting the skin and the hair, containing, in a cosmetically acceptable support, at least one compound of formula (1) or (2) in which X1 represents R3-(C-O)-, R3-SO2- or R3-O-(C-O)-, X2 represents -(C-O)-R'3-(C-O), -SO2-R'3-SO2- or -(C-O)-O-R'3-O-(C-O)-, Y represents -(C-O)-R4 or -SO2R5, R2 represents a C1-8 alkyl group, n is 0, 1 or 2, R3 represents C1-30 alkyl or C3-30 alkenyl, R'3 represents a single bond or a divalent C1-30 alkylene or C3-30 alkenylene radical, R4 represents -OR6 or -NHR6, R5 represents C1-30 alkyl or a phenyl nucleus, R6 represents C1-30 alkyl or C3-30 alkenyl, and novel compounds of formula (2).

Priority: US2004-0804128 Applic. Date: 2004-03-19; FR2001-0008092 Applic. Date: 2001-06-20; US2002-0174485 Applic. Date: 2002-06- 19

Inventor: RICHARD HERVE (FR); LUPPI BERNADETTE (FR)


Patent No.: US 7258695 B2 Issued: 2007-08-21
Publication No.: US20060178712A1 Published: 2006-08-10

Title: Hair restoration device and methods of using and manufacturing the same

Applicant: SONETICS INTERNAT (US); SUNETICS INTERNATIONAL L P (US)

Application No.: US2005-0053715 Applic. Date: 2005-02- 08

Abstract: The present invention provides for a hair restoration device and methods of manufacturing and using the same. In one embodiment, the hair restoration device is comprised of (i) a hairbrush body housing a plurality of wide-pattern laser LEDs configured to cooperate to project a precision laser light pattern at a focal plane proximate a skin area to be irradiated; and (ii) bristles extending from the hairbrush body and terminating substantially at the focal plane.

Priority: US2005-0053715 Applic. Date: 2005-02-08

Inventor: CARULLO JR JOHN F (US); MARICLE CHARLES E (US); CARULLO JOHN F JR (US)


Patent No.: US 7259109 B2 Issued: 2007-08-21
Publication No.: US20060267156A1 Published: 2006-11-30

Title: Electrospray and enhanced electrospray deposition of thin films on semiconductor substrates

Applicant: INTEL CORP (US)

Application No.: US2004-0947016 Applic. Date: 2004-09- 22

Abstract: A method of forming a thin film on a substrate to fabricate a microelectronic device, a microelectronic device comprising a thin film deposited according to the method, and a system comprising the microelectronic device. The thin film may include on of a low k thin film, a thin film comprising photoresist, and a sacrificial polymer. The method comprises dispersing a precursor preparation into a spray of charged droplets through subjecting the liquid precursor preparation to electrostatic forces; directing the charged droplets to move toward the substrate; and allowing the charged droplets to generate a beam of gas-phase ions as the charged droplets move toward the substrate. The method further includes directing the gas-phase ions to impinge upon the substrate to deposit the thin film thereon to yield a deposited thin film on the substrate.

Priority: US2004- 0947016 Applic. Date: 2004-09-22

Inventor: MEAGLEY ROBERT P (US)


Patent No.: US 7267673 B2 Issued: 2007-09- 11
Publication No.: US20040116913A1 Published: 2004-06-17

Title: System for treatment of acne skin condition using a narrow band light source

Applicant: PACIFIC BIOSCIENCES LAB INC (US)

Application No.: US2002-0317965 Applic. Date: 2002-12- 12

Abstract: The acne treatment devices use an array of LEDs, which emit monochromatic light substantially at a wavelength of 405 nanometers, which is coincident with the peak absorbance of light by acne porphyrins. The emitted light is directed from the light source to an acne area of the skin. The device can either be hand-held, with the LEDs mounted on a handle portion, or an LED can be mounted on a patch-like mounting element, which is adapted to be secured to the skin for longer exposure at less intensity.

Priority: US2002-0317965 Applic. Date: 2002-12- 12

Inventor: PILCHER KENNETH A (US); AKRIDGE ROBERT E (US); GIULIANI DAVID (US); HARRIS WARD E (US); MEGINNISS STEPHEN M (US)


Patent No.: US 7276059 B2 Issued: 2007-10-02
Publication No.: US20050015124A1 Published: 2005-01-20

Title: Treatment of skin disorders with UV light and cooling

Applicant: PHOTOMEDEX (US)

Application No.: US2004-0799337 Applic. Date: 2004-03-12

Abstract: Skin disorders such as, for example, atopic dermatitis, dyshidrosis, eczema, lichen planus, psoriasis, and vitiligo, are treated by applying high doses of ultraviolet light to diseased regions of a patient's skin. The dosage exceeds 1 MED, as determined for the particular patient and may range from about 1 MED to about 20 MED or higher. The ultraviolet light has a wavelength within the range of about 295 nanometers to about 320 nanometers. High doses of ultraviolet light are restricted to diseased tissue areas The skin can be cooled prior to and/or during exposure to UV light to minimize tissue damage resulting from exposure to the UV light. Higher doses of UV light can therefore be employed without injurious affects.

Priority: US2004-0799337 Applic. Date: 2004-03-12; US2002-0090096 Applic. Date: 2002-02-27; US2000-0694086 Applic. Date: 2000-10-20; US2001-0272277P Applic. Date: 2001-02-28

Inventor: IRWIN DEAN S (US)


Patent No.: US 7282060 B2 Issued: 2007-10-16
Publication No.: US20050154380A1 Published: 2005-07- 14

Title: Method and apparatus for monitoring and controlling laser-induced tissue treatment

Applicant: RELIANT TECHNOLOGIES INC (US)

Application No.: US2004- 0020648 Applic. Date: 2004-12-21

Abstract: The present invention provides methods and apparatus for controlling light-induced tissue treatment. In accordance with various aspects of the present invention, the invention provides for improved, real-time control of the light beam operational parameters which enables greater safety, efficiency, uniformity and continuity of the treatment process.

Priority: US2004-0020648 Applic. Date: 2004-12-21; US2003-0745761 Applic. Date: 2003-12-23; US2003-0750790 Applic. Date: 2003-12-31; US2004-0605092P Applic. Date: 2004-08- 26

Inventor: DEBENEDICTIS LEONARD C (US); MYERS THOMAS R (US); CHAN KIN F (US); FRANGINEAS JR GEORGE (US); FRANGINEAS GEORGE (US)


Patent No.: US 7288267 B2 Issued: 2007-10-30
Publication No.: US20030108611A1 Published: 2003-06-12

Title: Bioadhesive nanoparticulate compositions having cationic surface stabilizers

Applicant: ELAN PHARMA INT LTD (IE); ELAN PHARMA INT LTD (US)

Application No.: US2001-0004808 Applic. Date: 2001-12- 07

Abstract: Bioadhesive nanoparticulate compositions, comprising active agent particles and one or more cationic surface stabilizers, are described. The cationic surface stabilizers prevent aggregation of the nanoparticles and increase bioadhesion of the nanoparticles to biological substrates, such as an insect, teeth, bone, nails, chitin, feathers, scales, mucous, skin, hair, plant tissue, etc. The particles may consist of pharmacologically active compounds (e.g., drug compounds for human or veterinary use), agricultural chemicals (pesticides, herbicides, fertilizers, and the like), cosmetic agents, consumer products (coloring agents, flavors, or fragrances), or other materials which function by interacting with biological substrates. In addition, the invention relates to methods of preparing and using such bioadhesive nanoparticulate compositions.

Priority: US2001-0004808 Applic. Date: 2001-12-07; US1999-0414159 Applic. Date: 1999-10-08

Inventor: BOSCH H WILLIAM (US); COOPER EUGENE R (US); MCGURK SIMON L (US)


Patent No.: US 7291322 B2 Issued: 2007-11-06
Publication No.: US20070020204A1 Published: 2007-01-25

Title: Photoprotecting/cosmetic compositions comprising benzotriazole and bis-resorcinyltriazine

Applicant: OREAL (FR)

Application No.: US2006-0529618 Applic. Date: 2006-09-29

Abstract: Topically applicable sunscreen/cosmetic compositions suited for the improved photoprotection of human skin and/or hair against the damaging effects of UV-irradiation, particularly solar radiation, comprise an effective SPF-maintaining and water remanence-enhancing amount of intimate admixture of (a) at least one benzotriazole first sunscreen compound and (b) at least one bis-resorcinyltriazine second sunscreen compound, formulated into (c) a topically applicable, cosmetically acceptable vehicle, diluent or carrier therefor.

Priority: US2006-0529618 Applic. Date: 2006-09-29; FR1999-0001729 Applic. Date: 1999-02-12; US2004-0855350 Applic. Date: 2004-05-28; US2001-0927488 Applic. Date: 2001- 08-13; WO2000-FR00257 Applic. Date: 2000-02-03

Inventor: CANDAU DIDIER (FR)


Patent No.: US 7291497 B2 Issued: 2007-11-06
Publication No.: US20050100937A1 Published: 2005-05-12

Title: Medical device for analyte monitoring and drug delivery

Applicant: THERANOS INC (US)

Application No.: US2004-0937872 Applic. Date: 2004-09-10

Abstract: The invention relates to an ingestible, implantable or wearable medical device comprising a microarray which comprises a bioactive agent capable of interacting with a disease marker biological analyte; a reservoir which comprises at least one therapeutic agent and is capable of releasing the therapeutic agent(s) from the medical device; and a plurality of microchips comprising a microarray scanning device capable of obtaining physical parameter data of an interaction between the disease marker biological analyte with the bioactive agent; a biometric recognition device capable of comparing the physical parameter data with an analyte interaction profile; optionally a therapeutic agent releasing device capable of controlling release of the therapeutic agent from the reservoirs; an interface device capable of facilitating communications between the microarray scanning device, biometric recognition device and the therapeutic agent releasing device; and an energy source to power the medical device. Specifically, the invention relates to a medical device capable of detecting an analyte in a bodily fluid comprising at least one microneedle capable of obtaining a sample of a bodily fluid, a first microchannel through which the sample flows and is in fluid communication with the at least one microneedle, a second microchannel in fluid communication with the first microchannel, through which a buffer flows, wherein the second channel comprises a microarray with a bioactive agent, a microarray scanning device to detect an interaction between the bioactive agent and the analyte in the bodily fluid; and an interface device.

Priority: US2004-0937872 Applic. Date: 2004-09-10; US2003-0501847P Applic. Date: 2003-09-11

Inventor: HOLMES ELIZABETH A (US); ROY SHAUNAK (US); HOWARD JOHN (US); WANG CHENGWANG (US)


Patent No.: US 7294302 B2 Issued: 2007-11-13
Publication No.: US20040130066A1 Published: 2004-07- 08

Title: Method for controlling thickness of skin layer of composite resin molded product

Applicant: NISSEI PLASTICS IND CO (JP)

Application No.: US2003- 0716190 Applic. Date: 2003-11-18

Abstract: To control the thickness of the skin layer of a composite resin molded product by a viscosity difference obtained by varying the viscosity by adding another ultra-minute substance to a raw resin material. The composite resin molded product comprising the skin layer formed of a first thermoplastic resin and the core layer formed of a second thermoplastic resin is molded by injection. The viscosity difference between the resins is controlled by adding a carbon nanomaterial to one or the other of the thermoplastic resins. The thickness of the skin layer is controlled by the viscosity difference. The first thermoplastic resin and the second thermoplastic resin are of the same kind or different kinds of resins.

Priority: JP2002- 0335306 Applic. Date: 2002-11-19

Inventor: KOIDE ATSUSHI (JP); YAMAGIWA YOSHITOSHI (JP); SUGANUMA MASASHI (JP)


Patent No.: US 7294340 B2 Issued: 2007-11-13
Publication No.: US20050220829A1 Published: 2005-10-06

Title: Healthcare and cosmetic compositions containing nanodiamond

Application No.: US2004-0814660 Applic. Date: 2004-03- 30

Abstract: Nanodiamonds can be included in various compositions to take advantage of the ability of nanodiamond to bond with biological materials and to improve mechanical strength. Nanodiamonds can be dispersed in a biologically acceptable carrier to form various nanodiamond compositions. The presence of nanodiamonds can increase binding with many biological materials, making the compositions of the present invention useful for a large variety of purposes such as cleansing, testing and identification of materials, and treatment of adverse conditions. Specific examples of nanodiamond compositions that can be formulated include deodorants, toothpastes, shampoos, antibiotics, dermal strips, DNA test strips, skin cleansers, and the like. Similarly, nanodiamond particles can be included in a cosmetic nanodiamond composition within a cosmetically acceptable carrier.; Cosmetic nanodiamond compositions can include, for example, nail polish, eyeliner, lip gloss, exfoliant, and the like.

Priority: US2004-0814660 Applic. Date: 2004-03-30

Inventor: SUNG CHIEN-MIN (TW); SUNG MICHAEL (US); SUNG EMILY (US); SUNG CHIEN-MIN (CN)


Patent No.: US 7300649 B2 Issued: 2007-11- 27
Publication No.: US20060182770A1 Published: 2006-08-17

Title: COSMETIC AND COSMECEUTICAL COMPOSITIONS FOR RESTORATION OF SKIN BARRIER FUNCTION

Applicant: GENEPHARM INC (US)

Application No.: US2006-0275994 Applic. Date: 2006-02- 08

Abstract: Compositions, kits and methods are provided for restoring skin barrier function to skin exposed to environmental elements and/or in a pathological condition. In general, divalent cations such as calcium ions and/or magnesium ions are included in a physiologically acceptable medium. In some embodiments, divalent cations are balanced with monovalent cations such as sodium and potassium ions at appropriate ratios in order to maintain the homeostasis of skin barrier. The compositions, kits and methods can be used as cosmetics, cosmeceuticals or pharmaceuticals for improving skin condition, and preventing or treating dermatological diseases and skin disorders.

Priority: US2006-0275994 Applic. Date: 2006-02-08; US2005-0652196P Applic. Date: 2005-02-11

Inventor: TANOJO HANAFI (US); HUANG XINFAN (US)


Patent No.: US 7309482 B2 Issued: 2007-12- 18
Publication No.: US20070274931A9 Published: 2007-11-29
Publication No.: US20050249682A1 Published: 2005-11-10

Title: Long lasting waterproof sunscreen comprising metal oxide and peptide conditioner

Applicant: DU PONT (US)

Application No.: US2005-0069858 Applic. Date: 2005-02-28

Abstract: The disclosure provides a sunscreen formulation comprising a peptide-based metal oxide sunscreen agent, such as titanium dioxide nanoparticles, and a fluid vehicle.

Priority: US2005-0069858 Applic. Date: 2005-02-28; US2004-0935642 Applic. Date: 2004-09-07; US2003-0501498P Applic. Date: 2003 -09-08

Inventor: BUSEMAN-WILLIAMS JANINE (US); HUANG XUEYING (US); WANG HONG (US); WHITING GARY KEN (US); WHITING GARY K (US)


Patent No.: US 7312249 B2 Issued: 2007-12-25
Publication No.: US20050182144A1 Published: 2005-08-18

Title: Vitamin D analogues

Applicant: GALDERMA RES & DEV (FR)

Application No.: US2005- 0066795 Applic. Date: 2005-02-28

Abstract: Novel biaromatic vitamin D analogues have the general formula (I): and are suited for a wide variety of pharmaceutical applications, whether in human or veterinary medicine, and also for cosmetic applications.

Priority: US2005- 0066795 Applic. Date: 2005-02-28; WO2003-EP10159 Applic. Date: 2003-08-25; FR2002-0010620 Applic. Date: 2002-08-27; US2002-0407716P Applic. Date: 2002-09-04

Inventor: BIADATTI THIBAUD (FR); THOREAU ETIENNE (FR); VOEGEL JOHANNES (FR); JOMARD ANDRE (FR)


Patent No.: US 7316808 B2 Issued: 2008-01-08
Publication No.: US20040228813A1 Published: 2004-11-18

Title: Phase inverted oil-in-water photoprotective emulsions comprising nanopigments of metal oxides and 4,4-diarylbutadiene UV-A sunscreens

Applicant: OREAL (FR)

Application No.: US2004-0823640 Applic. Date: 2004-04-14

Abstract: Stable UV-photoprotective, phase inverted oil-in-water emulsions, well suited for the photoprotection of the skin, lips and/or hair, the average size of the globules which constitute the oily phase thereof ranging from 100 nm to 1,000 nm, contain inorganic metal oxide nanopigments and at least one organic UV-screening agent, and which also contain at least one organic 4,4-diarylbutadiene UV-A-screening agent.

Priority: US2004-0823640 Applic. Date: 2004-04-14; FR2003-0004645 Applic. Date: 2003-04-14; US2003-0468059P Applic. Date: 2003-05- 06

Inventor: CANDAU DIDIER (FR)


Patent No.: US 7316809 B2 Issued: 2008-01-08
Publication No.: US20040223924A1 Published: 2004-11-11

Title: Aqueous photoprotective compositions comprising diblock or triblock copolymers and 4,4-diarylbutadiene UV-A sunscreens

Applicant: OREAL (FR)

Application No.: US2004-0823659 Applic. Date: 2004-04-14

Abstract: Photoprotective compositions, e.g., oil-in-water or water- in-oil emulsions, well suited for the photoprotection of the skin, lips and/or hair against the damaging effects of UV-radiation, comprise at least one aqueous phase, at least one water-soluble or water- dispersible polymer having a diblock structure A-B or a triblock structure B-A-B wherein A is an ionic water-soluble polymeric block and B is a hydrophobic polymeric block and at least one system screening out UV radiation, said at least one screening system comprising at least one 4,4-diarylbutadiene UV-A screening agent.

Priority: FR2003-0004646 Applic. Date: 2003-04-14

Inventor: L ALLORET FLORENCE (FR)


Patent No.: US 7320797 B2 Issued: 2008-01-22
Publication No.: US20050048008A1 Published: 2005-03-03

Title: Antiaging Cosmetic Delivery Systems

Applicant: BIODERM RES (US)

Application No.: US2003-0604999 Applic. Date: 2003-08- 29

Abstract: The present invention provides a comprehensive solution to the problems associated with natural topical aging via the incorporation of: (i) An Extra-cellular antioxidant or Free-radical neutralizing composition, and (ii) An Intra-cellular antioxidant or Free-radical neutralizing composition, and (iii) An Anti-inflammatory composition, and (iv) A collagen or fibrin boosting composition. It is preferred to also have the above incorporated in a suitable carrier base or topical delivery system for skin, nail, and hair beneficial applications.

Priority: US2003-0604999 Applic. Date: 2003-08-29

Inventor: GUPTA SHYAM K (US)


Patent No.: US 7326407 B2 Issued: 2008-02- 05
Publication No.: US20060099159A1 Published: 2006-05-11

Title: Amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof

Applicant: OREAL (FR)

Application No.: US2005-0315249 Applic. Date: 2005-12-23

Abstract: Stable, topically applicable cosmetic/dermatological sunscreen compositions, well suited for the UV-photoprotection of human skin/keratinous materials, contain a thus effective amount of at least one novel amine, amide, sulphonamide or carbamate substituted benzalmalonic salt compound.

Priority: US2005- 0315249 Applic. Date: 2005-12-23; FR2003-0002561 Applic. Date: 2003-03-03; US2004-0787759 Applic. Date: 2004-02-27; US2003-0483652P Applic. Date: 2003-07-01

Inventor: RICHARD HERVE (FR); LUPPI BERNADETTE (FR)


Patent No.: US 7326803 B2 Issued: 2008-02-05
Publication No.: US20050148670A1 Published: 2005-07-07

Title: Ligand inhibitors of the RAR receptors, process for preparing same and therapeutic/cosmetic applications thereof

Applicant: GALDERMA RES & DEV (FR)

Application No.: US2004-0991430 Applic. Date: 2004-11-19

Abstract: Novel bicyclic compounds having the structural formula (I): are useful in a variety of pharmaceutical applications, whether human or veterinary, and also in cosmetics.

Priority: US2004-0991430 Applic. Date: 2004-11-19; WO2003-EP05555 Applic. Date: 2003-05-27; FR2002-0006851 Applic. Date: 2002- 06-04; US2002-0387447P Applic. Date: 2002-06-11

Inventor: BIADATTI THIBAUD (FR); COLLETTE PASCAL (FR)


Patent No.: US 7331964 B2 Issued: 2008-02-19
Publication No.: US20060178713A1 Published: 2006-08-10

Title: Laser therapy device for animals and methods of using the same and manufacturing the same

Applicant: SUNETICS INTERNATIONAL L P (US)

Application No.: US2005-0281807 Applic. Date: 2005-11-17

Abstract: The present invention provides for a laser therapy device for animals and methods of manufacturing and using the same. In one embodiment, the animal therapy device is comprised of (i) a hairbrush body housing a plurality of wide- pattern laser LEDs configured to cooperate to project a precision laser light pattern at a focal plane proximate an area to be irradiated; and (ii) bristles extending from the hairbrush body and terminating substantially at the focal plane. Laser light is used to treat different portions of the animal body.

Priority: US2005-0281807 Applic. Date: 2005-11-17; US2005-0053715 Applic. Date: 2005-02-08

Inventor: MARICLE CHARLES E (US); CARULLO JR JOHN F (US); CARULLO JOHN F JR (US)


Patent No.: US 7344530 B2 Issued: 2008-03-18
Publication No.: US20050080405A1 Published: 2005-04- 14

Title: Thermal surgical procedures and compositions

Applicant: UNIV MINNESOTA (US)

Application No.: US2004-0810956 Applic. Date: 2004-03- 26

Abstract: Methods, compositions, and systems useful to enhance a thermal surgical procedure are described. Compositions include at least one compound effective to induce an inflammatory response in biological material identified to undergo a thermal surgical procedure. Methods and systems include providing compositions of the invention to biological materials and treating biological materials with an inflammation inducing composition for a time, amount, and type effective to induce inflammation in at least a portion of the biological material.

Priority: US2004-0810956 Applic. Date: 2004-03-26; US2003-0457691P Applic. Date: 2003-03-26

Inventor: BISCHOF JOHN C (US); BELCHER JOHN D (US); VERCELLOTTI GREGORY M (US)


Patent No.: US 7348449 B2 Issued: 2008-03-25
Publication No.: US20050234131A1 Published: 2005-10-20

Title: Ligand antagonists of RAR receptors and pharmaceutical/cosmetic applications thereof

Applicant: GALDERMA RES & DEV (FR)

Application No.: US2005-0116344 Applic. Date: 2005-04- 28

Abstract: Novel ligand antagonists of the RAR receptors have the following structural formula (I): in which A is a CH2, CHOH, C-O or C-N-OH radical or a sulfur or selenium atom; B is a radical selected from among those of formulae (a) to (f): and Ar is a radical selected from among those of formulae (g) to (i):

Priority: US2005-0116344 Applic. Date: 2005-04-28; FR2002-0014391 Applic. Date: 2002-11-18; WO2003-EP14860 Applic. Date: 2003-11-18; US2002-0430640P Applic. Date: 2002 -12-04

Inventor: DIAZ PHILIPPE (FR); RAFFIN CATHERINE (FR); BIADATTI THIBAUD (FR)


Patent No.: US 7351462 B2 Issued: 2008-04-01
Publication No.: US20070022692A1 Published: 2007-02-01

Title: Synthetic Roofing Shingle or Tile

Applicant: CERTAIN TEED CORP (US)

Application No.: US2006-0531788 Applic. Date: 2006-09-14

Abstract: A synthetic roofing shingle or tile is provided, in which a core material is formed, of generally less expensive material, and with a skin material provided, disposed on a plurality of surfaces of the shingle or tile, with the skin material being generally of greater expense and having desirable weather-withstanding qualities.

Priority: US2006-0531788 Applic. Date: 2006-09-14; US2003-0452059 Applic. Date: 2003-06-02

Inventor: FRIEDMAN MICHAEL L (US); KALKANOGLU HUSNU M (US); KIM JOONG YOUN (US); MACKINNON THOMAS KEVIN (US); KIM JOONG Y (US); MACKINNON THOMAS K (US)


Patent No.: US 7354571 B2 Issued: 2008-04- 08
Publication No.: US20060018848A1 Published: 2006-01-26

Title: Photoprotective compositions comprising methyltrialkylsilanes containing a cinnamate, cinnamamide, benzalmalonamide or benzalmalonate function

Applicant: OREAL (FR)

Application No.: US2005-0189975 Applic. Date: 2005-07-27

Abstract: Unique photoprotective compositions contain novel methyltrialkylsilanes bearing a cinnamate, cinnamamide, benzalmalonamide or benzalmalonate function, useful as sunscreens that are active in the field of UV radiation.

Priority: US2005-0189975 Applic. Date: 2005-07-27; FR2003-0000909 Applic. Date: 2003-01-28; WO2003-EP15038 Applic. Date: 2003-12-19; US2003-0450708P Applic. Date: 2003-03- 03

Inventor: RICHARD HERVE (FR)


Patent No.: US 7354926 B2 Issued: 2008-04-08
Publication No.: US20060110413A1 Published: 2006-05-25

Title: Molecules derived from noraporphine

Applicant: SEDERMA SAS (FR)

Application No.: US2005-0525985 Applic. Date: 2005-09-15

Abstract: The invention concerns novel molecules derived from noraporphine, as well as cosmetic and dermopharmaceutical compositions containing one or several of said derivatives, alone or combined with a plant extract, in particular glaucium flavum, and particularly preparations for reducing pigmentation, with anti-ageing effect or for slimming.

Priority: FR2002-0010810 Applic. Date: 2002-08-30; WO2003-FR02400 Applic. Date: 2003-07-29

Inventor: LINTNER KARL (FR)


Patent No.: US 7357919 B2 Issued: 2008-04-15
Publication No.: US20060104924A1 Published: 2006-05-18

Title: Photostable photoprotective compositions comprising dibenzoylmethane and arylalkyl benzoate compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s)

Applicant: OREAL (FR)

Application No.: US2005-0249304 Applic. Date: 2005-10-14

Abstract: Topically applicable, improvedly photostabilized, photoprotective cosmetic/dermatological compositions contain (i) an effective UV-screening amount of at least one dibenzoylmethane sunscreen and an effective photostabilizing amount of (ii) at least one arylalkyl benzoate compound and (iii) at least one compound accepting the excited triplet level energy of said at least one dibenzoylmethane sunscreen, formulated into (iv) a topically applicable, cosmetically/dermatologically acceptable support therefor.

Priority: US2005-0249304 Applic. Date: 2005-10-14; FR2004-0052370 Applic. Date: 2004-10-19; US2004-0623038P Applic. Date: 2004-10-29

Inventor: CANDAU DIDIER (FR)


Patent No.: US 7357920 B2 Issued: 2008-04-15
Publication No.: US20060083698A1 Published: 2006-04-20

Title: Photostable photoprotective compositions comprising dibenzoylmethane and amide oil compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s)

Applicant: OREAL (FR)

Application No.: US2005-0249398 Applic. Date: 2005-10-14

Abstract: Topically applicable, improvedly photostabilized, photoprotective cosmetic/dermatological compositions contain (i) an effective UV-screening amount of at least one dibenzoylmethane sunscreen and an effective photostabilizing amount of (ii) at least one oil containing at least one amide structural unit and (iii) at least one compound accepting the excited triplet level energy of said at least one dibenzoylmethane sunscreen, formulated into (iv) a topically applicable, cosmetically/dermatologically acceptable support therefor.

Priority: US2005-0249398 Applic. Date: 2005-10-14; FR2004-0052367 Applic. Date: 2004-10-19; US2004-0623034P Applic. Date: 2004 -10-29

Inventor: CANDAU DIDIER (FR)


Patent No.: US 7357950 B2 Issued: 2008-04-15
Publication No.: US20040185123A1 Published: 2004-09-23

Title: Topical treatment for dyshidrosis (pompholyx) and dry skin disorders

Application No.: US2004-0801520 Applic. Date: 2004-03-16

Abstract: This invention discloses a topical herbal formulation for preventing and/or treating dyshidrosis (pompholyx), non-responsive to topical steroids. The formulation may also be used to treat contact dermatitis, eczema, palmoplantar pustulosis and skin infections incurred by invasive pathogens such as mold, fungus and bacteria. The formulation is comprised of plant extracts and niacin, that when combined yield an effective multi-faceted pharmaceutical approach to treating dry skin disorders. The active ingredients within the formula include a combination of dry, aqueous, acid and alcohol extracts of black walnut hull (Juglans Nigra), wormwood (Artemisia Absinthium), tumeric rhizome (Curcuma Longa), garlic (Allium sativum), chamomile (Matricaria Chamomile), licorice root (Glycyrrhiza Glabra), St Johns wort (Hypericum perforatum), aloe vera, niacin and herbal anti-bacterial agents.

Priority: US2004-0801520 Applic. Date: 2004-03-16; US2003-0456817P Applic. Date: 2003-03-21

Inventor: MAZZIO ELIZABETH ANNE (US); SOLIMAN KARAM F (US); MAZZIO ELIZABETH A (US)


Patent No.: US 7364720 B2 Issued: 2008-04-29
Publication No.: US20060002873A1 Published: 2006-01-05

Title: Photostabilization of dibenzoylmethane UV-screening agents with arylalkyl benzoate compounds/amide-based oils and photoprotective compositions comprised thereof

Applicant: OREAL (FR)

Application No.: US2005-0172902 Applic. Date: 2005-07-05

Abstract: The present invention relates to a process for photostabilizing, with respect to UV radiation, at least one dibenzoylmethane derivative with at least one arylalkyl benzoate derivative and at least one oil containing in its structure at least one amide unit. Another subject of the invention also relates to a novel cosmetic or dermatological composition for topical use, characterized in that it comprises, in a cosmetically acceptable support: (a) at least one UV-screening agent of the dibenzoylmethane derivative type and (b) at least one arylalkyl benzoate derivative and (c) at least one oil containing in its structure at least one amide unit.; The present invention also relates to the use of an arylalkyl benzoate derivative and an oil containing in its structure at least one amide unit in a cosmetic or dermatological composition comprising at least one dibenzoylmethane derivative, for the purpose of improving the stability with respect to UV rays of the said dibenzoylmethane derivative.

Priority: US2005-0172902 Applic. Date: 2005-07-05; FR2004-0051417 Applic. Date: 2004-07-02; US2004-0589010P Applic. Date: 2004-07- 20

Inventor: CANDAU DIDIER (FR)


Patent No.: US 7364721 B2 Issued: 2008-04-29
Publication No.: US20060008430A1 Published: 2006-01-12

Title: Photostabilization of dibenzoylmethane UV-screening agents with arylalkyl benzoate compounds and photoprotective cosmetic compositions comprised thereof

Applicant: OREAL (FR)

Application No.: US2005-0172949 Applic. Date: 2005-07-05

Abstract: Topically applicable cosmetic/dermatological photoprotective compositions contain at least one dibenzoylmethane UV-screening agent, and, as a photostabilizer therefor, at least one arylalkyl benzoate compound of formula (I) or (II) below: with the proviso that: (i) the subject compositions are characteristically devoid of any octyl methoxycinnamate; and (ii) same are other than a solution of butyl methoxydibenzoylmethane in 2- phenylethyl benzoate, 2-phenylethyl o-toluate, 2-phenylethyl p-toluate or in a 2-phenylethyl o- toluate/2-phenylethyl p-toluate (1/1) mixture.

Priority: US2005-0172949 Applic. Date: 2005-07-05; FR2004-0051416 Applic. Date: 2004-07-02; US2004-0588984P Applic. Date: 2004-07- 20

Inventor: CANDAU DIDIER (FR)


Patent No.: US 7365844 B2 Issued: 2008-04-29
Publication No.: US20050080343A1 Published: 2005-04-14

Title: Vision enhancement system for improved detection of epithelial neoplasia and other conditions

Applicant: UNIV TEXAS (US)

Application No.: US2003-0732199 Applic. Date: 2003-12- 10

Abstract: Systems and methods for diagnosing epithelial neoplasia and other conditions includes, in a representative embodiment, providing the human eyes with a filter to observe the autofluorescence of a tissue sample. Using optimized wavelengths from a filtered light source, a sample is illuminated. The radiation from the sample is filtered to enhance the contrast between a normal sample and a diseased sample observable by the human eye.

Priority: US2003-0732199 Applic. Date: 2003-12-10; US2002-0432122P Applic. Date: 2002-12-10

Inventor: RICHARDS-KORTUM REBECCA (US); UTZINGER URS (US); SVISTUN EKATERINA S (US); GILLENWATER ANN (US)


Patent No.: US 7367934 B2 Issued: 2008-05- 06
Publication No.: US20050256360A1 Published: 2005-11-17

Title: Methods of enhancing radiation effects with metal nanoparticles

Applicant: NANOPROBES INC (US)

Application No.: US2005-0186675 Applic. Date: 2005-07-21

Abstract: The present invention provides methods of using metal nanoparticles 0.5 to 400 nm in diameter to enhance the dose and effectiveness of x-rays or of other kinds of radiation in therapeutic regimes of ablating a target tissue such as tumor. The metal nanoparticles can be administered intravenously, intra- arterially, or locally to achieve specific loading in and around the target tissue. The metal nanoparticles can also be linked to chemical and/or biochemical moieties which bind specifically to the target tissue. The enhanced radiation methods can also be applied to ablate unwanted tissues or cells ex vivo.

Priority: US2005-0186675 Applic. Date: 2005-07-21; US2003-0387059 Applic. Date: 2003-03-12; US1998-0094669P Applic. Date: 1998-07-30; US1999-0363204 Applic. Date: 1999-07- 29

Inventor: HAINFELD JAMES F (US); SLATKIN DANIEL N (US)


Patent No.: US 7368105 B2 Issued: 2008-05-06
Publication No.: US20060008429A1 Published: 2006-01-12

Title: Photostabilization of dibenzoylmethane UV-screening agents with arylalkyl benzoate/bis-resorcinyl triazine compounds and photoprotective compositions comprised thereof

Applicant: OREAL (FR)

Application No.: US2005-0172932 Applic. Date: 2005-07-05

Abstract: Topically applicable, photostable compositions with respect to UV radiation contain at least one dibenzoylmethane UV-screening agent and at least one arylalkyl benzoate compound and at least one bis-resorcinyl triazine compound.

Priority: US2005-0172932 Applic. Date: 2005-07-05; FR2004-0051419 Applic. Date: 2004-07-02; US2004-0589009P Applic. Date: 2004-07-20

Inventor: CANDAU DIDIER (FR)


Patent No.: US 7381403 B2 Issued: 2008-06-03
Publication No.: US20040258644A1 Published: 2004-12-23

Title: Finely divided photoprotective oil-in-water emulsions comprising 4,4-diarylbutadiene UV-A sunscreens

Applicant: OREAL (FR)

Application No.: US2004-0823715 Applic. Date: 2004-04-14

Abstract: UV-Photoprotective oil-in-water emulsions well suited for photoprotecting the skin, lips and/or hair against the damaging effects of UV-radiation, the oil globules of which having an average size of at most 500 nm and containing particles of at least one ionic polymer and at least one UV-radiation-screening system, such screening system comprising at least one 4,4-diarylbutadiene UV-A-screening agent.

Priority: US2004-0823715 Applic. Date: 2004 -04-14; FR2003-0004648 Applic. Date: 2003-04-14; US2003-0468113P Applic. Date: 2003-05- 06

Inventor: SIMONNET JEAN-THIERRY (FR)


Patent No.: US 7400789 B2 Issued: 2008-07-15
Publication No.: US20070116401A1 Published: 2007-05-24

Title: METHOD, SYSTEM AND MODULE FOR MONITORING A POWER GENERATING SYSTEM

Applicant: GEN ELECTRIC (US)

Application No.: US2006-0468162 Applic. Date: 2006-08-29

Abstract: A sensing module positioned about an optical fiber cable having a long axis. The optical fiber includes a core that transmits light through the optical fiber cable. The sensing module includes a first short-period fiber grating positioned about the core. A second short-period fiber grating is positioned about the core and at a distance along the long axis with respect to the first short-period fiber grating. At least one of a long-aperiod fiber grating and a long-period fiber grating is positioned between the first short- period fiber grating and the second short-period fiber grating. A fiber cladding is positioned around the long-period grating and/or the long-aperiod grating of the sensing module. A sensing skin is positioned about the fiber cladding and includes a chemical gas active material.

Priority: US2006-0468162 Applic. Date: 2006-08-29; US2005-0284595 Applic. Date: 2005-11- 22

Inventor: XIA HUA (US); DENG KUNG-LI JUSTIN (US); MCCARTHY KEVIN THOMAS (US); TAWARE AVINASH VINAYAK (US); DENG KUNG-LI J (US); MCCARTHY KEVIN T (US); TAWARE AVINASH V (US)


Patent No.: US 7402301 B2 Issued: 2008-07-22
Publication No.: US20060177396A1 Published: 2006-08-10

Title: Sunscreen compositions comprising metal oxide mineral pigments and hydroxyalkylurea compounds

Applicant: OREAL (FR)

Application No.: US2005-0311650 Applic. Date: 2005-12-20

Abstract: The invention relates to a composition comprising, in a cosmetically acceptable carrier, a system for screening out UV radiation, characterized in that it contains: (a) at least metal oxide-based mineral pigments, and (b) at least one hydroxyalkylurea of formula (I) below: in which R1, R2, R3 and R4 each independently represent a hydrogen atom, a C1-C4 alkyl group or a C2-C6 hydroxy-alkyl group that may contain from 1 to 5 hydroxyl groups, at least one of the radicals R1-R4 representing a hydroxyalkyl group, and also a salt, solvate or isomer thereof, said composition containing no kojic dipalmitate. The invention also relates to the use of a hydroxyalkylurea of formula (I) in a composition comprising, in a cosmetically acceptable carrier, at least metal oxide- based mineral pigments, for reducing, or even eliminating, the whitening effect on the keratin material after application.

Priority: US2005-0311650 Applic. Date: 2005-12-20; FR2004-0053078 Applic. Date: 2004-12-20; US2005-0646598P Applic. Date: 2005-01-26

Inventor: CANDAU DIDIER (FR)


Patent No.: US 7413800 B2 Issued: 2008-08-19
Publication No.: US20050208282A1 Published: 2005-09- 22

Title: Co-extruded biaxially oriented sealable, peelable film and process for its production

Applicant: TERPHANE INC (US)

Application No.: US2004-0951333 Applic. Date: 2004-09-27

Abstract: A peelable sealable co-extruded film, comprising: i. a skin layer capable of heat sealing against a rim of a container, to itself, or to another film and adapted to be peeled there from and comprising a hot melt adhesive resin; and ii. a core layer underlying said skin layer and comprising crystalline homopolymer polyethylene terephthalate; and a method for the preparation thereof.

Priority: US2004-0951333 Applic. Date: 2004-09- 27; US2004-0555346P Applic. Date: 2004-03-22

Inventor: WOOD JR RONALD C (US); VIEIRA MARCOS FERNANDES (BR); WOOD RONALD C JR (US); VIEIRA MARCOS F (BR)


Patent No.: US 7431917 B2 Issued: 2008-10-07
Publication No.: US20060083699A1 Published: 2006-04-20

Title: Photostable photoprotective compositions comprising dibenzoylmethane and bis-resorcinyl triazine compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s)

Applicant: OREAL (FR)

Application No.: US2005-0249521 Applic. Date: 2005-10- 14

Abstract: Topically applicable, improvedly photostabilized, photoprotective cosmetic/dermatological compositions contain (i) an effective UV-screening amount of at least one dibenzoylmethane sunscreen and an effective photostabilizing amount of (ii) at least one bis-resorcinyl triazine compound and (iii) at least one compound accepting the excited triplet level energy of said at least one dibenzoylmethane sunscreen, notably at least one 4-hydroxybenzylidenemalonate compound, 4- hydroxycinnamate compound, fluorene compound, piperidinol salt, or mixture thereof, formulated into (iv) a topically applicable, cosmetically/dermatologically acceptable support therefor.

Priority: US2005-0249521 Applic. Date: 2005-10-14; FR2004-0052368 Applic. Date: 2004-10-19; US2004-0623580P Applic. Date: 2004-10-29

Inventor: CANDAU DIDIER (FR)


Patent No.: US 7435846 B2 Issued: 2008-10-14
Publication No.: US20080044475A1 Published: 2008-02-21

Title: Absorption and bioavailability of carotenoids, formulations and applications

Applicant: IND ORGANICA S A DE C V (MX)

Application No.: US2006-0506974 Applic. Date: 2006-08 -18

Abstract: A process for obtaining a microscopic physical state of xanthophylls or oxycarotenoids derivatives forms such as diacetates or dipropionates derivatives, which are readily incorporated in the digestive system as micelles providing an improved bioavailability, as compared to the bioavailability of carotenoids that are ingested in diverse preparations that contain microscopic carotenoids crystals and a method for its application.

Priority: US2006-0506974 Applic. Date: 2006-08-18

Inventor: OLVERA RICARDO MONTOYA (MX); QUIROGA JOSE TORRES (MX)


Patent No.: US 7442674 B2 Issued: 2008-10-28
Publication No.: US20050233916A1 Published: 2005-10-20

Title: Beauty wash product compositions delivering enhanced visual benefits to the skin with specific optical attributes

Applicant: UNILEVER HOME & PERSONAL CARE (US)

Application No.: US2005-0043509 Applic. Date: 2005-01-26

Abstract: The present invention relates to compositions delivering enhanced visual benefits to the skin with specific optical attributes. These are delivered using specific deposition systems (where oil/emollient comprises part of deposition system) and/or by ensuring dispersion of particles.

Priority: US2005-0043509 Applic. Date: 2005-01-26; US2004-0996532 Applic. Date: 2004-11-24; US2004-0815003 Applic. Date: 2004- 03-31

Inventor: POLONKA JACK (US); HAMILTON BRIAN KEITH (US); LIPS ALEXANDER (US); CHANDAR PREM (US); TSAUR LIANG SHENG (US); HAMILTON BRIAN K (US)


Patent No.: US 7449200 B2 Issued: 2008-11-11
Publication No.: US20070243259A1 Published: 2007-10-18

Title: Nanoparticles for protein/peptide delivery and delivery means

Applicant: GP MEDICAL INC (US); NAT TSING HUA UNIVERISTY (TW)

Application No.: US2006-0405066 Applic. Date: 2006-04- 17

Abstract: The invention discloses the biodegradable nanoparticle for use in nanoparticle projectile bombardment as a carrier for administering proteins or peptides to an animal subject. The nanoparticles are composed of positively charged shell substrate, negatively charged core substrate with encapsulated bioactive agents of proteins or peptides.

Priority: US2006- 0405066 Applic. Date: 2006-04-17

Inventor: SUNG HSING-WEN (TW); CHEN MEI-CHIN (TW); LEE PO-WEI (TW); TU HOSHENG (US)


Patent No.: US 7453407 B2 Issued: 2008-11-18
Publication No.: US20080158072A1 Published: 2008-07-03

Title: ANTENNA CONSTRUCTIONS FOR ELECTRONIC DEVICES AND METHODS FOR MANUFACTURING SUCH ANTENNA CONSTRUCTIONS

Applicant: GOODYEAR TIRE & RUBBER (US)

Application No.: US2006-0618744 Applic. Date: 2006-12- 30

Abstract: Antenna constructions for electronic devices and methods of manufacturing such antenna constructions. The electronic device comprises a transponder and an antenna electrically coupled with the transponder. The antenna has a core of a first material and a coating of a second material on the core. The second material has a higher electrical conductivity than the first material and/or a lower permeability than the first material. The coating on the core also has a predetermined thickness. The electronic devices may be used in tires.

Priority: US2006-0618744 Applic. Date: 2006-12-30

Inventor: LOGAN BRIAN MATTHEW (US); BENEDICT ROBERT LEON (US)


Patent No.: US 7459283 B2 Issued: 2008-12-02
Publication No.: US20030185869A1 Published: 2003-10-02

Title: Nanoparticulate compositions having lysozyme as a surface stabilizer

Applicant: ELAN PHARMA INT LTD (IE); ELAN PHARMA INT LTD (US)

Application No.: US2003-0357514 Applic. Date: 2003-02-04

Abstract: The present invention is directed to nanoparticulate active agent compositions comprising lysozyme as a surface stabilizer. Also encompassed by the invention are pharmaceutical compositions comprising a nanoparticulate active agent composition of the invention and methods of making and using such nanoparticulate and pharmaceutical compositions.

Priority: US2003-0357514 Applic. Date: 2003-02-04; US2002-0353230P Applic. Date: 2002-02-04

Inventor: WERTZ CHRISTIAN F (US); RYDE NIELS P (US)


Patent No.: US 7462388 B2 Issued: 2008-12- 09
Publication No.: US20040131841A1 Published: 2004-07-08

Title: Conductive resin molded product having insulating skin and method for forming the same

Applicant: NISSEI PLASTICS IND CO (JP)

Application No.: US2003-0722116 Applic. Date: 2003-11-25

Abstract: The present invention relates to a conductive resin molded product having an insulating skin produced by a composite comprising a non-conductive resin and conductive material. The invention also provides a method for producing the conductive resin molded product.

Priority: JP2002-0347673 Applic. Date: 2002-11-29

Inventor: KOIDE ATSUSHI (JP); YAMAGIWA YOSHITOSHI (JP); SUGANUMA MASASHI (JP); TAKAHASHI YOSHIHIKO (JP)


Patent No.: US 7462753 B2 Issued: 2008-12-09
Publication No.: US20070293799A1 Published: 2007-12-20

Title: Nano-silver wound dressing

Applicant: CHUNG SHAN INST OF SCIENCE (TW)

Application No.: US2006-0455188 Applic. Date: 2006-06-19

Abstract: A nano-silver wound dressing consisting of a skin contact layer made from hydrophilic cloth and directly contacting a wound on the surface of the skin, a disinfecting (or bactericidal) antitoxic layer made from activated charcoal cloth impregnated with nanocrystalline silver, a blood absorbing and styptic layer made from a superabsorbent polymer non-woven cloth, an isolation layer made from a composite fabric with a pore size of less than 5 mum, and an elastic bandage for fixing a main body on the site of wound. Edges of the isolation layer and the skin contact layer are integrated to form a main body while the disinfecting (or bactericidal) antitoxic layer as well as the blood absorbing and styptic layer are separated from each other and both enclosed inside the main body.

Priority: US2006-0455188 Applic. Date: 2006-06-19

Inventor: MA RIN-HSIUNG (TW); YU YI-HSIUAN (TW)


Patent No.: US 7465879 B2 Issued: 2008-12- 16
Publication No.: US20060237219A1 Published: 2006-10-26

Title: Concentric-eccentric high performance, multi-media communications cables and cable support-separators utilizing roll-up designs

Applicant: CABLE COMPONENTS GROUP (US); CABLE COMPONENTS GROUP LLC

Application No.: US2006-0408452 Applic. Date: 2006-04- 21

Abstract: The present invention includes a high performance communications cable or cable support-separator and/or jacket and includes one or more core support-separators having various shaped profiles. The core may be formed of conductive or insulative material and may be comprised of polymer blends that include olefin and/or fluoropolymer and/or chlorofluoropolymer based resins with or without inorganic additives such as nano-clay composites, C60 based compounds, etc. The core support- separator has both a central region as well as a plurality of shaped sections that extend outward from the central region that are either solid or partially solid, foamed or foamed with a solid skin surface. The invention includes incorporation of hollow ducts that can be used to provide for insertion of optical or metal transmission media either before, during, or after installation of the cable.

Priority: US2006-0408452 Applic. Date: 2006-04-21; US2005-0674526P Applic. Date: 2005-04-25

Inventor: GLEW CHARLES A (US)


Patent No.: US 7468195 B2 Issued: 2008-12-23
Publication No.: US20070218045A1 Published: 2007-09-20

Title: SKIN TREATMENT PREPARATION

Applicant: CRAWFORD HEALTHCARE LTD (GB)

Application No.: US2007 -0744731 Applic. Date: 2007-05-04

Abstract: A skin treatment preparation including carriers, a medicinal vector encapsulating a plant extract (Cucumis melo protein extract) rich in reductase, catalase and superoxide dismutase is characterized in that the medicinal vector, of nanospheres, represents 1 to 20 wt. % of the weight of the preparation; and the encapsulated plant extract represents 5 to 15 wt. % of the weight of the nanospheres; and the encapsulated plant extract may have the following enzymatic concentrations: reductase between 100 and 1000 IU, catalase between 100 and 1000 IU, and superoxide dismutase between 500 and 5000 IU. The preparation is useful for limiting depigmentation and reducing inflammatory front in vilitigo pathology and possible repigmentation.

Priority: US2007-0744731 Applic. Date: 2007-05-04; US2003-0311148 Applic. Date: 2003-04-09; WO2000-FR01601 Applic. Date: 2000-06-09

Inventor: DIEHL CHRISTIAN (FR)


Patent No.: US 7469060 B2 Issued: 2008-12-23
Publication No.: US20060104488A1 Published: 2006-05- 18

Title: Infrared face detection and recognition system

Applicant: HONEYWELL INT INC (US)

Application No.: US2004-0987368 Applic. Date: 2004-11- 12

Abstract: A face detection and recognition system having several arrays imaging a scene at different bands of the infrared spectrum. The system may use weighted subtracting and thresholding to distinguish human skin in a sensed image. A feature selector may locate a face in the image. The face may be framed or the image cropped with a frame or border to incorporate essentially only the face. The border may be superimposed on an image direct from an imaging array. A sub-image containing the face may be extracted from within the border and compared with a database of face information to attain recognition of the face. A level of recognition of the face may be established. Infrared lighting may be used as needed to illuminate the scene.

Priority: US2004-0987368 Applic. Date: 2004-11- 12

Inventor: BAZAKOS MICHAEL E (US); MORELLAS VASSILIOS (US); JOHNSON ANDREW (US); MA YUNQIAN (US); MA YUNGIAN (US)


Patent No.: US 7473722 B2 Issued: 2009-01-06
Publication No.: US20060099405A1 Published: 2006-05-11

Title: Polymer-fiber composite building material with bulk and aesthetically functional fillers

Applicant: CERTAIN TEED CORP (US); CERAINTEED CORP

Application No.: US2004-0983389 Applic. Date: 2004-11- 08

Abstract: Polymer composite building materials are provided which contain resin, and about 20-75 wt. % fillers and additives, in which the fillers contain at least one bulk filler for reducing the amount of resin needed to make the building material, and at least one aesthetically functional filler for providing the building material with an aesthetic appearance. The bulk filler and the aesthetically functional filler of this embodiment are non-toxic, resistant to microbial attack, and have a Mohs hardness of less than about 5.

Priority: US2004-0983389 Applic. Date: 2004-11 -08

Inventor: GUISELIN OLIVIER (US); KALKANOGLU HUSNU (US); LE GOFF CHRISTELLE POUSSE (FR); ELINSKI RANDALL J (US); QUIST GREGORY P (US); RUEDE PAUL (US); HILLS RICHARD A (US); LE GOFF CHRISTELLE P (FR)


Patent No.: US 7473849 B2 Issued: 2009-01-06
Publication No.: US20060237217A1 Published: 2006-10- 26

Title: Variable diameter conduit tubes for high performance, multi-media communication cable

Applicant: CABLE COMPONENTS GROUP (US); CABLE COMPONENTS GROUP LLC

Application No.: US2006-0408444 Applic. Date: 2006-04- 21

Abstract: The present invention describes a conduit tube like structure for high performance, multi-media communications cables with or without support separators that are of varying internal and external dimensions and wall thickness that may vary consistently or randomly and may be spirally or helically wound within or around a high performance, multi-media communications cable to vary the spacing between a high performance, multi-media communications cable and an adjacent communications cable. The conduit tube structures may be hollow, contain communications media, solid comprised of various shapes and wrapped with various windings and/or tensions. The final cable assembly may then be jacketed or taped as desired.

Priority: US2006-0408444 Applic. Date: 2006-04- 21; US2005-0674526P Applic. Date: 2005-04-25

Inventor: GLEW CHARLES A (US)


Patent No.: US 7473850 B2 Issued: 2009-01-06
Publication No.: US20060237218A1 Published: 2006-10-26

Title: High performance, multi-media cable support-separator facilitating insertion and removal of conductive media

Applicant: CABLE COMPONENTS GROUP (US); CABLE COMPONENTS GROUP LLC

Application No.: US2006-0408451 Applic. Date: 2006-04- 21

Abstract: The present invention includes a high performance communication cable support-separator that includes one or more core support-separators having various shaped profiles which define and maintain a spacing between transmission media or transmission media pairs. The cable channels have longitudinal gaps that allow for insertion and removal of conductive transmission media to aid in terminating and connecting the transmission media. The cable support-separator channel intermediary may be additionally separated from each other.

Priority: US2006-0408451 Applic. Date: 2006-04 -21; US2005-0674526P Applic. Date: 2005-04-25

Inventor: GLEW CHARLES A (US)


Patent No.: US 7476514 B2 Issued: 2009-01-13
Publication No.: US20030199006A1 Published: 2003-10-23

Title: Method for monitoring the immune response and predicting clinical outcomes in transplant recipients

Applicant: CYLEX INC (US)

Application No.: US2003-0411353 Applic. Date: 2003-04-11

Abstract: Methods for monitoring the immune response and predicting clinical outcomes for patients on immunosuppressive drugs (such as transplant patients) are provided. The methods are based on the measurement of an intracellular metabolic marker in lymphocytes (such as ATP) as an indicator of a patient's immune response.

Priority: US2003-0411353 Applic. Date: 2003-04-11; US2002-0371402P Applic. Date: 2002-04-11

Inventor: BRITZ JUDITH A (US); SOTTONG PETER R (US); KOWALSKI RICHARD J (US)


Patent No.: US 7476699 B2 Issued: 2009-01-13
Publication No.: US20070274933A1 Published: 2007-11-29

Title: Amino- and hydroxysubstituted triphenyl-S-triazines as stabilizers

Applicant: CIBA SC HOLDING AG (US)

Application No.: US2007-0891554 Applic. Date: 2007-08-10

Abstract: The present invention provides compounds having the formula: in which R is hydrogen, hydroxy, halogen, C1-C20-alkyl, C4-C12cycloalkyl, C2-C20alkenyl, C2-C20alkynyl, C1-C20-alkoxy, C4-C12cycloalkoxy, C2- C20alkenoxy, C2-C20alkynoxy or C7-C13aralkyl; R1 and R2, independently, are hydrogen, C1-C20alkyl, C4- C12cycloalkyl, C7-C13 aralkyl, -C(-O)-R4 (in which R4 is C1-C20alkyl, C2-C20alkyl interrupted by 1 to 6 oxygen atoms, hetero-substituted C1-C20alkyl, C4-C12cycloalkyl, C2-C20alkenyl, C2-C20alkynyl, C1-C20- alkoxy, C4-C12cycloalkoxy, C2-C20alkenoxy, C2-C20alkynoxy, C6-C12 aryl, C6-C12 aryloxy or C7-C13 aralkyl), or -C(-O)-NH-R1 in which R1 has its previous significance; and R3 is hydrogen, halogen, hydroxy, C1-C20alkyl, C4-C12cycloalkyl, C2-C20alkenyl, C2-C20alkynyl, C1-C20-alkoxy, C4-C12cycloalkoxy, C2-C20alkenoxy, C2-C20alkynoxy, phenyl, C7-C13 aralkyl or -N(R1)(R2) in which R1 and R2 have their previous significance, or R1 and R2 together form a C4-C12 membered ring. The new triphenyltriazine compounds have improved absorption spectrum characteristics and superior resistance to exposure to UV light, relative to known triphenyltriazine compounds.

Priority: US2007-0891554 Applic. Date: 2007-08-10; GB1996-0006970 Applic. Date: 1996-04-02; US2001-0013885 Applic. Date: 2001-12-11; US2000-0651615 Applic. Date: 2000-08-30; US1998-0155560 Applic. Date: 1998-09-30; WO1997-EP01331 Applic. Date: 1997-03-17

Inventor: REINEHR DIETER (DE); METZGER GEORGES (FR); MICHAELIS PETER (FR); LUTHER HELMUT (DE)


Patent No.: US 7510703 B2 Issued: 2009-03-31
Publication No.: US20070224147A1 Published: 2007-09-27

Title: UV-photoprotecting/sunscreen compositions comprising silane/siloxane derivatives of merocyanine sulfones

Applicant: OREAL (FR)

Application No.: US2007-0725485 Applic. Date: 2007-03-20

Abstract: Topically applicable cosmetic compositions useful for the UV-A photoprotection of the skin and/or hair contain thus effective amounts of at least one silane, siloxane or polysiloxane merocyanine sulfone having at least one of the structural formulae (1), (2) and (3) below:

Priority: US2007- 0725485 Applic. Date: 2007-03-20; FR2004-0052093 Applic. Date: 2004-09-20; WO2005-FR02129 Applic. Date: 2005-08-24; US2004-0613967P Applic. Date: 2004-09-29

Inventor: RICHARD HERVE (FR)


Patent No.: US 7528100 B2 Issued: 2009-05-05
Publication No.: US20060111263A1 Published: 2006-05- 25

Title: Derivatized polysaccharide polymer

Applicant: RHODIA (US)

Application No.: US2005-0282501 Applic. Date: 2005-11-18

Abstract: Derivatized polysaccharide polymers that contain a fructan polymer substrate bearing one or more cationic substituent groups are useful in home and fabric care applications, in oilfield applications, and in emulsion polymerization applications.

Priority: US2005-0282501 Applic. Date: 2005- 11-18; US2004-0629402P Applic. Date: 2004-11-19

Inventor: GUNN EUEN (US); GABBIANELLI ALVINO (US); CROOKS REGAN (US); SHANMUGANANDAMURTHY KRISHNAMURTHY (US); SHANMUGANANDAMURTHY KRISHNAMUR (US)


Patent No.: US 7530940 B2 Issued: 2009-05-12
Publication No.: US20050020869A1 Published: 2005-01- 27

Title: Methods of enhancing radiation effects with metal nanoparticles

Applicant: NANOPROBES INC (US)

Application No.: US2003-0705614 Applic. Date: 2003-11-10

Abstract: The present invention provides methods of using metal nanoparticles 0.5 to 400 nm in diameter to enhance the dose and effectiveness of x-rays or of other kinds of radiation in therapeutic regimes of ablating a target tissue, such as tumor. The metal nanoparticles can be administered intravenously, intra-arterially, or locally to achieve specific loading in and around the target tissue. The metal nanoparticles can also be linked to chemical and/or biochemical moieties which bind specifically to the target tissue. The enhanced radiation methods can also be applied to ablate unwanted tissues or cells ex vivo.

Priority: US2003-0705614 Applic. Date: 2003-11-10; US2003-0387059 Applic. Date: 2003-03-12; US1999-0363204 Applic. Date: 1999- 07-29; US1998-0094669P Applic. Date: 1998-07-30

Inventor: HAINFELD JAMES F (US); SLATKIN DANIEL N (US)


Patent No.: US 7534421 B2 Issued: 2009-05-19
Publication No.: US20040258636A1 Published: 2004-12- 23

Title: s-Triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof

Applicant: OREAL (FR)

Application No.: US2004-0787940 Applic. Date: 2004-02- 27

Abstract: Stable, topically applicable cosmetic/dermatological sunscreen compositions, well suited for the UV-photoprotection of human skin/keratinous materials, contain a thus effective amount of at least one novel s-triazine compound bearing at least one para-aminobenzalmalonic salt substituent.

Priority: US2004-0787940 Applic. Date: 2004-02-27; FR2003-0002562 Applic. Date: 2003-03-03; US2003-0468995P Applic. Date: 2003-05-09

Inventor: RICHARD HERVE (FR); LUPPI BERNADETTE (FR)


Patent No.: US 7564245 B2 Issued: 2009-07-21
Publication No.: US20070116602A1 Published: 2007-05-24

Title: NMR device for detection of analytes

Applicant: T2 BIOSYSTEMS INC (US); BIOPLEX SYSTEMS INC (US)

Application No.: US2006-0513503 Applic. Date: 2006-08-31

Abstract: This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.

Priority: US2006-0513503 Applic. Date: 2006-08-31; US2005-0713176P Applic. Date: 2005-08-31

Inventor: LEE W DAVID (US); LEE W D (US)


Patent No.: US 7572160 B2 Issued: 2009-08- 11
Publication No.: US20070212957A1 Published: 2007-09-13

Title: Mimetic gear

Application No.: US2007-0714042 Applic. Date: 2007-03- 05

Abstract: Methods and compositions which can reduce the disturbance to wild life caused when man attempts to interact with wild life and more particularly methods and compositions which can enhance the interaction of man with aquatic life with minimal disturbance to the aquatic life.

Priority: US2007-0714042 Applic. Date: 2007-03-05; US2004-0998217 Applic. Date: 2004-11-26; US2003-0525292P Applic. Date: 2003-11-26

Inventor: HALLIDAY CHRISTOPHER I (US)


Patent No.: US 7575589 B2 Issued: 2009-08-18
Publication No.: US20070179571A1 Published: 2007-08- 02

Title: Light-emitting device and method for providing phototherapy to the brain

Applicant: PHOTOTHERA INC (US)

Application No.: US2006-0385988 Applic. Date: 2006-03-21

Abstract: An apparatus emits light for irradiating a patient's skin to treat portions of a patient's body underneath the patient's skin. The apparatus includes a source of light having a wavelength which is substantially transmitted by the patient's skin. The apparatus further includes an optical conduit optically coupled to the source. The apparatus further includes an output optical element comprising a rigid and substantially thermally conductive material. The output optical element is optically coupled to the optical conduit.

Priority: US2006- 0385988 Applic. Date: 2006-03-21; US2006-0763261P Applic. Date: 2006-01-30

Inventor: DE TABOADA LUIS (US); STREETER JACKSON (US)


Patent No.: US 7592277 B2 Issued: 2009-09-22
Publication No.: US20060264140A1 Published: 2006-11-23

Title: Nanofiber Mats and production methods thereof

Applicant: RES TRIANGLE INST (US)

Application No.: US2005- 0130269 Applic. Date: 2005-05-17

Abstract: An apparatus and method in which the apparatus includes a first electrospinning device configured to electrospin first fibers of a first substance, a second electrospinning device configured to electrospin second fibers of a second substance such that first and second fibers combine in a mat formation region, and a biasing device configured to bias the first electrospinning device with a first electric polarity and to bias the second electrospinning device with a second electric polarity of opposite polarity to the first electric polarity to promote attraction and coalescence between the first and second fibers. The method electrospins under the first electric polarity first fibers from the first substance, electrospins under the second electric polarity fibers from the second substance, and coalesces the first and second fibers to form the fiber mat.

Priority: US2005-0130269 Applic. Date: 2005-05- 17

Inventor: ANDRADY ANTHONY L (US); ENSOR DAVID S (US); WALKER TERI A (US); PRABHU PURVA (US)


Patent No.: US 7592478 B2 Issued: 2009-09-22
Publication No.: US20080213347A1 Published: 2008-09- 04

Title: Ligand antagonists of RAR receptors and pharmaceutical/cosmetic applications thereof

Applicant: GALDERMA RES & DEV (FR)

Application No.: US2007- 0978623 Applic. Date: 2007-10-30

Abstract: Novel ligand antagonists of the RAR receptors have the following structural formula (I): in which A is a CH2, CHOH, C-O or C-N-OH radical or a sulfur or selenium atom; B is a radical selected from among those of formulae (a) to (f): and Ar is a radical selected from among those of formulae (g) to (i):

Priority: US2007-0978623 Applic. Date: 2007-10-30; FR2002-0014391 Applic. Date: 2002-11-18; US2005-0116344 Applic. Date: 2005-04-28; WO2003-EP14860 Applic. Date: 2003-11-18

Inventor: DIAZ PHILIPPE (FR); RAFFIN CATHERINE (FR); BIADATTI THIBAUD (FR)


Patent No.: US 7597664 B2 Issued: 2009-10-06
Publication No.: US20070043293A1 Published: 2007-02-22

Title: Measuring transducer movement methods and systems for multi-dimensional ultrasound imaging

Applicant: SIEMENS MEDICAL SOLUTIONS (US)

Application No.: US2006-0590569 Applic. Date: 2006-10-30

Abstract: Methods and systems for measuring transducer movement are provided. For example, free-hand scanning for three-dimensional imaging is provided. An optical sensor within the transducer measures motion along the skin surface similar to measuring movement of a personal computer mouse with an optical sensor. Alternatively or additionally, the transducer is tilted at an angle other than perpendicular to the skin surface generally towards or away from the direction in which the transducer is translated. The transducer is then translated while maintaining the angle. Motion to or from the transducer is measured, and a component of the motion measured while the transducer is maintained at an angle is parallel to the direction of translation. The component of motion is angle corrected and used to determine a distance of travel.

Priority: US2006-0590569 Applic. Date: 2006-10-30; US2003-0372423 Applic. Date: 2003-02-20

Inventor: JONES PAUL H (US); FREIBURGER PAUL D (US); ROBINSON CRAIG B (US); CZENSZAK STEPHEN P (US); DEFORGE CHRISTIAN (US)


Patent No.: US 7597708 B2 Issued: 2009-10-06
Publication No.: US20060178714A1 Published: 2006-08-10

Title: Hair restoration device and methods of using and manufacturing the same

Applicant: SUNETICS INTERNATIONAL L P (US)

Application No.: US2006-0350553 Applic. Date: 2006-02-09

Abstract: The present invention provides for a hair restoration device and methods of manufacturing and using the same. In one embodiment, the hair restoration device is comprised of (i) a hairbrush body housing a plurality of wide-pattern laser LEDs configured to cooperate to project a precision laser light pattern at a focal plane proximate a skin area to be irradiated; and (ii) bristles extending from the hairbrush body and terminating substantially at the focal plane.

Priority: US2006-0350553 Applic. Date: 2006-02-09; US2005-0053715 Applic. Date: 2005-02-08

Inventor: CARULLO JR JOHN F (US); MARICLE CHARLES E (US); CARULLO JOHN F JR (US)


Patent No.: US 7597879 B2 Issued: 2009-10-06
Publication No.: US20070189992A1 Published: 2007-08-16

Title: Sunscreen safety and efficacy enhancement

Applicant: BIODERM RES (US)

Application No.: US2007-0676284 Applic. Date: 2007-02-17

Abstract: The present invention discloses safety and efficacy enhancement of sunscreens with certain heterocyclic base complexes of manganese via urocanate pathway modulation. The present invention also discloses a method for topical application of said complexes, which causes the reduction of topical peroxide including hydrogen peroxide, the reduction of topical inflammation including sunburn, increased sun protection of skin, the reduction of skin wrinkles, comprehensive protection from UVA, UVB, and UVC, and reduction of radiation-initiated inflammation.

Priority: US2007-0676284 Applic. Date: 2007-02-17; US2006-0308290 Applic. Date: 2006-03-15; US2002-0306948 Applic. Date: 2002-11-29; US2004-0710011 Applic. Date: 2004-06- 11

Inventor: GUPTA SHYAM K (US)


Patent No.: US 7602942 B2 Issued: 2009-10-13
Publication No.: US20060102843A1 Published: 2006-05-18

Title: Infrared and visible fusion face recognition system

Applicant: HONEYWELL INT INC (US)

Application No.: US2004-0987806 Applic. Date: 2004-11-12

Abstract: A face detection and recognition system having several arrays imaging a scene in the infrared and visible spectrums. The system may use weighted subtracting and thresholding to distinguish human skin in a sensed image. A feature selector may locate a face in the image. The image may be cropped with a frame or border incorporating essentially only the face. The border may be superimposed on images from an infrared imaging array and the visible imaging array. Sub-images containing the face may be extracted from within the border on the infrared and visible images, respectively, and compared with a database of face information to attain recognition of the face. Confidence levels of recognition for infrared and visible imaged faces may be established. A resultant confidence level of recognition may be determined from these confidence levels.; Infrared lighting may be used as needed to illuminate the scene.

Priority: US2004-0987806 Applic. Date: 2004-11-12

Inventor: BAZAKOS MICHAEL E (US); MORELLAS VASSILIOS (US); MA YUNQIAN (US)


Patent No.: US 7604381 B2 Issued: 2009-10-20
Publication No.: US20080252980A1 Published: 2008-10-16

Title: OPTICAL ARTICLE AND METHOD OF MAKING

Applicant: 3M INNOVATIVE PROPERTIES CO (US)

Application No.: US2007- 0735684 Applic. Date: 2007-04-16

Abstract: Disclosed herein is an optical article having a top layer with a structured surface that collimates light, a core layer secured to the top layer opposite the structured surface, and a bottom layer secured to the core layer opposite the top layer. Either the top layer or the core layer includes a first extrudable polymer having a flexural modulus of greater than 2.5 GPa, and the other layer includes a second extrudable polymer having a flexural modulus of 2.5 GPa or less, an impact strength of greater than about 40 J/m, and tensile elongation at break of greater than about 5%. The bottom layer includes a third extrudable polymer. The bottom layer of the optical article may be structured to diffuse light. One or two optical articles may be secured to an optical film such as a polarizer film. Methods and display devices are also disclosed herein.

Priority: US2007-0735684 Applic. Date: 2007-04-16

Inventor: HEBRINK TIMOTHY J (US); JONZA JAMES M (US); BAY RANDY S (US); CLARKE GRAHAM M (US); LUCKING RAYMOND L (US); YU TA-HUA (US); COLLIER TERRY O (US)


Patent No.: US 7608204 B2 Issued: 2009-10-27
Publication No.: US20080241414A1 Published: 2008-10-02

Title: CONDUCTIVE INK COMPOSITION AND METHOD OF FORMING A CONDUCTIVE PATTERN USING THE SAME

Applicant: SAMSUNG ELECTRONICS CO LTD (KR)

Application No.: US2008-0018892 Applic. Date: 2008-01-24

Abstract: A conductive ink composition includes about 15% to about 50% by weight of copper nanoparticles, about 40% to about 80% by weight of a non-aqueous solvent mixture, about 0.01% to about 5% by weight of a dispersion agent and about 1% to about 20% by weight of a wetting agent. A conductive pattern may be formed with use of the conductive ink composition and an inkjet printer.

Priority: KR2007 -0031284 Applic. Date: 2007-03-30

Inventor: KIM JANG-SUB (KR); LIM SOON-KWON (KR); MOON JOO-HO (KR); JEONG SUN-HO (KR); KIM DONG-JO (KR); WOO KYOO-HEE (KR); KIM JANG SUB (KR)


Patent No.: US 7615104 B2 Issued: 2009-11-10
Publication No.: US20070095206A1 Published: 2007-05-03

Title: Fuel deoxygenation system with multi-layer oxygen permeable membrane

Applicant: UNITED TECHNOLOGIES CORP (US); MEMBRANE TECHNOLOGY & RES INC (US)

Application No.: US2005- 0265845 Applic. Date: 2005-11-03

Abstract: A fuel system for an energy conversion device includes a deoxygenator system with an oxygen permeable membrane formed from a multiple of layers. The layers include a sealant layer, an oxygen permeability layer and a porous backing layer. The layered composite oxygen permeable membrane maximizes the oxygen transfer rate and minimizes the fuel leakage rate.

Priority: US2005-0265845 Applic. Date: 2005-11-03

Inventor: CORDATOS HARALAMBOS (US); SPADACCINI LOUIS J (US); PINNAU INGO (US)


Patent No.: US 7639342 B2 Issued: 2009-12-29
Publication No.: US20080220183A1 Published: 2008-09-11

Title: FERROELECTRIC COMPOSITE, METHOD OF MANUFACTURING THE SAME AND LIQUID CRYSTAL DISPLAY APPARATUS HAVING THE FERROELECTRIC COMPOSITE

Applicant: SAMSUNG ELECTRONICS CO LTD (KR)

Application No.: US2008-0968667 Applic. Date: 2008-01-03

Abstract: A ferroelectric composite includes a core including a ferroelectric material and a skin layer including a carbon structure comprising carbon atoms.

Priority: KR2007-0023477 Applic. Date: 2007-03- 09

Inventor: HWANG TAE-HYUNG (KR); BAN BYEONG-SEOB (KR)


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