US Patent Applications in Nano-technology for Hair Care
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US PATENT APPLICATIONS IN NANOTECHNOLOGY FOR HAIR CARE PUBLISHED FROM 2001 TO 2009



Publication No.: US Appl: 20010031247 A1 Published: 2001-10-18
Patent No.: US6372200B2 Issued: 2002-04-16

Title: UV-photoprotecting sunscreen compositions comprising immixture of polyethylene/carboxylated polyethylene polymers

Applicant: OREAL (FR)

Application No.: US2001-0771661 Applic. Date: 2001-01-30

Abstract: Topically applying cosmetic/dermatological compositions well suited for both effective and SPF-enhanced UV-photoprotection of human skin and/or hair contain (a) an effective UV-photoprotecting amount of at least one UV-A and/or UV-B sunscreen and (b) an amount of immixture of ethylene polymers effective to enhance the SPF value of said at least one UV-A and/or UV-B sunscreen (a), said immixture of ethylene polymers (b) comprising (i) at least one carboxylated polyethylene and (ii) at least one polyethylene, formulated into a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor, advantageously formulated as an oil-in-water emulsion.

Priority: FR2000-0001535 Applic. Date: 2000-02-08

Inventor: JOSSO MARTIN (FR); MEURISSE STEPHANIE (FR)


Publication No.: US Appl: 20020021932 A1 Published: 2002-02-21
Patent No.: US6682244B2 Issued: 2004-01-27

Title: Devices and methods for dispensing

Applicant: OREAL (FR)

Application No.: US2001-0859444 Applic. Date: 2001-05-18

Abstract: A device for dispensing comprises a reservoir containing a composition comprising particles containing at least one fluid, an application member having at least a portion removably disposed within the reservoir and configured to be loaded with the composition and a compacting member configured to exert pressure on at least the portion of the application member during removal of the portion of the application member from the reservoir.

Priority: FR2000-0006449 Applic. Date: 2000-05-19

Inventor: GUERET JEAN LOUIS H (FR); GUERET JEAN-LOUIS H (FR)


Publication No.: US Appl: 20030024878 A1 Published: 2003-02-06
Patent No.: US6951891B2 Issued: 2005-10-04

Title: Process to make dispersions

Applicant: AKZO NOBEL NV (NL)

Application No.: US2002-0209047 Applic. Date: 2002-07-31

Abstract: The present invention relates to the production of dispersions and is particularly suitable for making dispersions with a viscous or solid dispersed phase in a continuous phase with a lower viscosity.

Priority: US2002-0209047 Applic. Date: 2002-07-31; US2001-0309947P Applic. Date: 2001-08-03

Inventor: BALTUSSEN JOZEF JOHANNES MARIA (NL); VISSER JAN (NL)


Publication No.: US Appl: 20030104020 A1 Published: 2003-06-05
Patent No.: US6638918B2 Issued: 2003-10-28

Title: Chitosan compositions

Applicant: PROCTER & GAMBLE (US)

Application No.: US2002-0280617 Applic. Date: 2002-10-25

Abstract: Compositions comprising chitosan in the form of a network of nano-sized fibres. There is also provided a process for making such compositions. The compositions have improved solubility and activity. The compositions are useful in hair care, skin care, odour control, wound care, blood management, sanitary compositions, oral care, film formation, hard surface treatment, fabric treatment, release of hydrophobic or hydrophilic materials, plant care, water purification and drug delivery.

Priority: GB2001-0026923 Applic. Date: 2001-11-09

Inventor: DAVISON GORDON ROBERT (GB); KONIG AXEL (BE); GIBBONS CLYDE (GB); RIPLEY MARK BRIAN (GB); MACGILP NEIL ARCHIBALD (GB); MILICH GEORGINA LYNDSEY CLAIRE (GB); PRETSWELL EMMA LOUISE (GB)


Publication No.: US Appl: 20030138507 A1 Published: 2003-07-24
Patent No.: US6861078B2 Issued: 2005-03-01

Title: Plant extracts with anti-radical type action

Applicant: COGNIS FRANCE SA (FR)

Application No.: US2002-0307977 Applic. Date: 2002-12-03

Abstract: The use of plant extracts, especially plant extracts with an anti-radical-type action, and a cosmetic or dermopharmaceutical composition containing extracts of this type. The use of at least one plant extract whose botanical genus belongs to the group formed by the following: Clidemia, Inga, Sabicea, Astrocaryum, Siparuna, Eperua, Byrsonima, Priva, Coutoubea and Goupia genera; as an active substance which has especially anti-radical-type activities, for preparing a cosmetic or dermopharmaceutical product for local, external use for the skin, the mucous membranes and/or the epithet or appendage structures.

Priority: US2002-0307977 Applic. Date: 2002-12-03; FR1998-0015380 Applic. Date: 1998-12-03; US2001-0857445 Applic. Date: 2001-06-04

Inventor: PAULY GILLES (FR); MORETTI CHRISTIAN (FR)


Publication No.: US Appl: 20030195133 A1 Published: 2003-10-16
Patent No.: US7053034B2 Issued: 2006-05-30

Title: Targeted controlled delivery compositions activated by changes in pH or salt concentration

Applicant: SALVONA LLC (US)

Application No.: US2002-0119567 Applic. Date: 2002-04-10

Abstract: The present invention relates to a novel controlled release carrier system for pH or salt triggered release and targeted delivery of fragrances and other active ingredients onto fabric, hair, skin, and other biological surfaces and which provides prolonged release of fragrances and other active ingredients over an extended period of time, or yields a high impact fragrance "burst" upon treating the target surface with heat (blow drying the hair, ironing the fabric). The controlled delivery system of the present invention is substantially a free-flowing powder formed of solid hydrophobic nano-spheres comprising the fragrance and other active ingredients that are encapsulated in a pH or salt sensitive micro-spheres. Also described are processes for preparing such compositions and processes for using same.; Furthermore, certain components of the aforementioned compositions in combination with one another are novel, and other components have novel uses in increasing fragrance substantivity, particularly in fabric, hair, and skin care preparations. The invention further pertains to consumer and diversified products comprising the controlled release system of the present invention.

Priority: US2002-0119567 Applic. Date: 2002-04-10

Inventor: SHEFER ADI (US); SHEFER SHMUEL DAVID (US)


Publication No.: US Appl: 20030215479 A1 Published: 2003-11-20

Title: Process for manufacture of hair or skin cosmetic products using apparatuses with microstructured units

Application No.: US2003-0426095 Applic. Date: 2003-04-29

Abstract: A process for manufacturing hair cosmetic or skin cosmetic products is described, in which the products contain a preparation with hair cosmetic or skin cosmetic ingredients and one process step includes conducting at least a part of the preparation through an apparatus with microstructured units. The apparatus with microstructured units can be one or more static micromixers and/or one or more microheat exchangers.

Priority: DE2002-1019523 Applic. Date: 2002-05-02

Inventor: SENDELBACH GERHARD (DE); KELLER WALTER (DE); SPIKA HANS JOACHIM (DE); GOCKELN GERLINDE (DE); SPRINGOB CHRISTIAN (DE); ALLWOHN JUERGEN (DE)


Publication No.: US Appl: 20030224060 A1 Published: 2003-12-04

Title: Polyester polyol nanocapsules, compositions thereof, and methods of use

Applicant: OREAL (FR)

Application No.: US2003-0364364 Applic. Date: 2003-02-12

Abstract: The present invention relates generally to nanocapsules having a core-envelope structure where the core contains a lipophilic active agent and the envelope contains at least one polyester polyol obtained by polycondensation of an aliphatic dicarboxylic acid with at least two alkanediols or with at least one alkanediol and at least one hydroxyalkyl alkanediol. These nanocapsules make it possible to stabilize lipophilic active agents that are difficult to stabilize, especially retinol esters such as retinyl propionate.

Priority: US2003-0364364 Applic. Date: 2003-02-12; FR2002-0002290 Applic. Date: 2002-02-22; US2002-0361707P Applic. Date: 2002-03-06

Inventor: SIMONNET JEAN-THIERRY (FR); GUERIN GILLES (FR)


Publication No.: US Appl: 20030232091 A1 Published: 2003-12-18

Title: Stabilized retinol for cosmetic dermatological, and pharmaceutical compositions, and use thereof

Application No.: US2002-0172292 Applic. Date: 2002-06-17

Abstract: The present invention relates to a controlled release system useful to stabilize retinol, retinol derivatives, and extracts containing retinol in cosmetic, dermatological, and pharmaceutical compositions. More specifically, the present invention pertains to stabilized retinol in a solid hydrophobic particle that sustains the release of retinol during the product shelf life and enables a gradual and prolonged release of effective levels of retinol and other cosmetic, dermatological, and pharmaceutical active ingredients into biological surfaces. The present invention also refers to a process of stabilizing retinol, retinol derivatives, and extracts containing retinol in cosmetic, dermatological, and pharmaceutical compositions.; The invention further relates to cosmetic, dermatological, and pharmaceutical products comprising stable retinol in a hydrophobic particle that can deliver effective levels of retinol and other cosmetic, dermatological, and pharmaceutical active ingredients to biological surfaces over an extended period of time.

Priority: US2002-0172292 Applic. Date: 2002-06-17

Inventor: SHEFER ADI (US); SHEFER SAMUEL DAVID (US)


Publication No.: US Appl: 20040014700 A1 Published: 2004-01-22
Patent No.: US7087743B2 Issued: 2006-08-08

Title: Novel oligonucleotides and use of oligonucleotides modulating the expression of enzymes involved in the synthesis of melanic pigments, as depigmentation agents

Applicant: LVMH RECH (FR)

Application No.: US2003-0203398 Applic. Date: 2003-01-06

Abstract: The present invention relates to novel oligonucleotide sequences and also to derivatives thereof. These novel oligonucleotide sequences are capable of hybridizing specifically with the gene or with a product of the gene encoding tyrosinase, or with the gene or a product of the gene encoding tyrosinase-related-protein 1 (TRP-1). The present invention also relates to the use of these novel oligonucleotide sequences as a depigmenting or bleaching agent in a cosmetic composition or in a dermatological composition.

Priority: FR2000-0001730 Applic. Date: 2000-02-11; WO2001-FR00398 Applic. Date: 2001-02-09

Inventor: KURFURST ROBIN (FR); JOLY REGINE (FR)


Publication No.: US Appl: 20040018165 A1 Published: 2004-01-29

Title: Hair care compositions

Applicant: PROCTER & GAMBLE (US)

Application No.: US2003-0616076 Applic. Date: 2003-07-08

Abstract: A hair-care composition comprising an anti-dandruff effective amount of anti-microbial oligoaminosaccharide comprising at least about 50%, preferably at least about 80% by weight of oligoaminosacharides having from 1 to 50 monomer units. The invention also relates to the use of the anti-microbial oligoaminosaccharide in a hair-care composition for providing anti-dandruff activity.

Priority: EP2002-0255162 Applic. Date: 2002-07-23

Inventor: KONIG AXEL (BE); RIPLEY MARK BRIAN (GB); DAVISON GORDON ROBERT (GB)


Publication No.: US Appl: 20040052760 A1 Published: 2004-03-18
Patent No.: US7320967B2 Issued: 2008-01-22

Title: Cosmetic composition, method of cosmetic treatment and preparation of a composition for promoting the growth and/or preventing or delaying the loss of hair

Applicant: OREAL (FR)

Application No.: US2003-0420831 Applic. Date: 2003-04-23

Abstract: The invention relates to a cosmetic composition containing at least one 15-hydroxyprostaglandin dehydrogenase inhibitor and cosmetically acceptable excipients. It also relates to a method of cosmetic treatment for promoting the growth and/or preventing or delaying the loss of hair, and the use of a 15-hydroxyprostaglandin dehydrogenase inhibitor for the preparation of a composition intended for controlling hair loss and/or for promoting hair regrowth.

Priority: US2003-0420831 Applic. Date: 2003-04-23; FR2002-0005067 Applic. Date: 2002-04-23; FR2002-0013461 Applic. Date: 2002-10-28; US2002-0387420P Applic. Date: 2002-06-11; US2002-0425330P Applic. Date: 2002-11-12

Inventor: MICHELET JEAN-FRANCOIS (FR); BERNARD BRUNO (FR); ROZOT ROGER (FR); BOULLE CHRISTOPHE (FR)


Publication No.: US Appl: 20040097398 A1 Published: 2004-05-20
Patent No.: US7208465B2 Issued: 2007-04-24

Title: Methods and compositions for improved fragrancing of a surface

Applicant: PROCTER & GAMBLE (US)

Application No.: US2003-0428246 Applic. Date: 2003-05-02

Abstract: The invention provides a method for improving release, on a surface, of a fragrance from an entrapment structure of at least one fragrance oil and at least one entrapment material. The method destabilises the entrapment structure by providing at least one trigger molecule which preferentially associates with the entrapment material; and/or at least one release agent which at least partially disrupts the entrapment structure. The invention also provides a composition for improving release of a fragrance from a surface. The composition comprises at least one fragrance oil; at least one entrapment material, the at least one fragrance oil and the at least one entrapment material being capable, in use, of forming an entrapment structure on the surface. The composition also comprises at least one destabilising material, which permits formation of the entrapment structure on the surface but which destabilising material can, in use, destabilise the entrapment structure by providing at least one trigger molecule which preferentially associates with the entrapment material; and/or at least one release agent which partially disrupts the entrapment structure; and at least one compatible solvent which doesn't interfere with the formation of the entrapment structure on the surface. The present methods and compositions can improve fragrance perception, by overcoming the differences in fragrance perception that result from different surface, for example, skin, hydration levels and/or different surface types.

Priority: US2003-0428246 Applic. Date: 2003-05-02; EP2000-0650180 Applic. Date: 2000-11-03; WO2001-US45017 Applic. Date: 2001-10-31

Inventor: HELTOVICS GABOR (HU); HOLLAND LYNETTE ANNE MAKINS (GB); WARWICK JANE MARGARET (GB); JENKINS DELYTH MYFANWY (GB); SUTTON KAREN LORRAINE (GB); PRETSWELL EMMA LOUISE (GB); SHEFFERD ANDREW JAMES PETER (GB)


Publication No.: US Appl: 20040107080 A1 Published: 2004-06-03

Title: Method for modelling customised earpieces

Application No.: US2003-0469591 Applic. Date: 2003-09-02

Abstract: The present invention relates to a method for computer-controlled modelling of customised earpieces. These earpieces include housings for hearing aids, wireless or connected communication devices (headsets, mobile phones, personal agents), loud speakers, tinnitus masking devices, devices recording vibrations in the skull and transforming these into audio signals, voice recognition devices, earplugs, noise blockers with selective frequencies or sound levels, Man Machine Interface (MMI) products that enable clear communication even in the noisiest environments, or products related to wireless Internet applications. All these earpieces may be worn in the user's meatus and/or auditory canal. The invention also relates to a computerised system for manufacturing such customised earpieces.; In particular, the invention is directed to a computerised system that models an earpiece based on a three-dimensional replica of the user's meatus and/or auditory canal.

Priority: DK2001-0000346 Applic. Date: 2001-03-02; DK2001-0000519 Applic. Date: 2001-03-28; DK2001-0001521 Applic. Date: 2001-10-17; WO2002-DK00137 Applic. Date: 2002-03-01

Inventor: DEICHMANN NIKOLAJ (DK); CLAUSEN TAIS (DK); FISKER RUNE (DE); VASILJEV BARTHE CHRISTOPHE (DK)


Publication No.: US Appl: 20040115766 A1 Published: 2004-06-17

Title: Method for producing proteins by fermentation of microorganisms from the thermus family the protein mixture thus obtained and cosmetic compositions containing same

Application No.: US2004-0468081 Applic. Date: 2004-01-08

Abstract: The use of fermentation media for microorganisms from the Thermus family, in particular microorganisms collected in marine waters close to very deep hydrothermal sources, especially those obtained with the GY1211 strain. Cosmetic compositions containing one or more types of fermentation media for the microorganisms and which are used, in particular, for skin care, notably for the face, body and scalp, and hair care and in order to modulate the cutaneous concentration of ceramides, to stimulate the immune system, to provide protection by means of the chaperone effect and a detoxifying and anti-free radical effect, particularly in relation to the oxygen peroxide.

Priority: FR2001-0002442 Applic. Date: 2001-02-21; WO2002-FR00488 Applic. Date: 2002-02-07

Inventor: LINTNER KARL (FR)


Publication No.: US Appl: 20040120918 A1 Published: 2004-06-24

Title: Cosmetic or dermopharmaceutical compositions of ceramides and polypeptides

Applicant: SEDERMA S A S (FR)

Application No.: US2003-0742344 Applic. Date: 2003-12-19

Abstract: Personal care products including cosmetics, grooming products and topical pharmaceutical products can be produced including a polypeptide of between 3 and 12 amino acids in length and a ceramide. These formulations are particularly useful in addressing wrinkles in human subjects and in particular facial skin and hands. Certain analogs and derivatives of these polypeptides may be used in these formulations and/or alone. Methods of using these formulations are also disclosed.

Priority: FR2003-0005707 Applic. Date: 2003-05-12

Inventor: LINTNER KARL (FR); GABRIELE DENISE E (US)


Publication No.: US Appl: 20040121019 A1 Published: 2004-06-24

Title: Particles comprising a biopolymer which is degradable under the effect of an electromagnetic wave as emitted by a solar radiation

Applicant: COLETICA (FR)

Application No.: US2003-0346690 Applic. Date: 2003-01-15

Abstract: The invention relates mainly to a particle comprising at least one biopolymer which is degradable under the effect of an electromagnetic wavelength, notably the wavelength of which is in the spectrum of the wavelengths emitted by the sun, this biopolymer comprising nucleosides. The invention also relates to compositions containing such particles with the aim of delivering an active principle. These particles can be used mainly in cosmetics, in dermatology, in pharmacy, in agri-food or en agro-industrials.

Priority: FR2002-0016637 Applic. Date: 2002-12-24

Inventor: PERRIER ERIC (FR); BONNET ISABELLE (FR); DE MATTEIS CHARLOTTE (FR)


Publication No.: US Appl: 20040151673 A1 Published: 2004-08-05

Title: Nonaerosol/aerosol dispensing of sunscreen sprays comprising silica microparticles

Applicant: OREAL (FR)

Application No.: US2003-0717523 Applic. Date: 2003-11-21

Abstract: Nonaerosol/atomizer pumps or aerosol dispensers comprise (A) a reservoir confining at least one vaporizable sunscreen composition suited for UV-photoprotecting the skin and/or hair against the damaging effects of UV radiation, the at least one vaporizable sunscreen composition comprising (1) a UV-photoprotecting amount of at least one UV-sunscreen and (2) an SPF-enhancing amount of generally spherical silica microparticles, formulated into (3) a topically applicable, cosmetically acceptable carrier therefor, and (B) at least one agent for pressurizing the at least one vaporizable sunscreen composition into a spray of fine sunscreen particles.

Priority: US2003-0717523 Applic. Date: 2003-11-21; FR2002-0014599 Applic. Date: 2002-11-21; US2003-0449574P Applic. Date: 2003-02-26

Inventor: JOSSO MARTIN (FR)


Publication No.: US Appl: 20040180147 A1 Published: 2004-09-16
Patent No.: US7132122B2 Issued: 2006-11-07

Title: Direct micro-patterning of lipid bilayers using UV light and selected uses thereof

Applicant: UNIV CALIFORNIA (US)

Application No.: US2003-0698995 Applic. Date: 2003-10-30

Abstract: This invention provides novel methods for creation of patterned lipid bilayer membranes as well as methods for refunctionalization of such patterned membranes with selected components. Such components optionally comprise, e.g., lipid bilayer membranes (which optionally comprise specific proteins), proteins, non-biologic moieties, etc.

Priority: US2003-0698995 Applic. Date: 2003-10-30; US2002-0422902P Applic. Date: 2002-10-30; US2002-0423327P Applic. Date: 2002-10-31; US2003-0469928P Applic. Date: 2003-05-12; US2003-0496256P Applic. Date: 2003-08-18

Inventor: PARIKH ATUL NAVINCHANDRA (US); YEE CHANEL KITMON (US); AMWEG MERI LYNN (US)


Publication No.: US Appl: 20050142092 A1 Published: 2005-06-30

Title: Cosmetic or dermopharmaceutical compositions which are used to reduce bags and circles under the eyes

Application No.: US2005-0504643 Applic. Date: 2005-02-25

Abstract: The invention relates to novel cosmetic or dermopharmaceutical compositions for topical use which are used to prevent the symptoms of cutaneous slackening and, more specifically, to treat the visible signs of ageing and fatigue, such as bags and circles under the eyes. The inventive compositions comprise, in a cosmetically-acceptable medium, a combination of at least two, and preferably three, components selected from: a) hesperidin or the derivatives thereof; b) A.C.E. enzyme inhibitor dipeptides; and c) oligopeptides R2-(AA)n-Pro-Arg-OH, wherin (AA)n is a peptide chain, (AA) is any amino acid or any derivative of any amino acid, n is included between 1 and 3, and R2-H or an alkyl chain having a carbon length of between C2 and C22.

Priority: FR2002-0001967 Applic. Date: 2002-02-15; WO2003-FR00441 Applic. Date: 2003-02-10

Inventor: LINTNER KARL (FR)


Publication No.: US Appl: 20050153862 A1 Published: 2005-07-14
Patent No.: US7338928B2 Issued: 2008-03-04

Title: System and process for releasing encapsulated active ingredients

Applicant: ROHM & HAAS (US)

Application No.: US2004-0003869 Applic. Date: 2004-12-03

Abstract: The present invention relates to a controlled release system that can be incorporated in cosmetic, personal care, and household products to effectively encapsulate wide range of active ingredients and sensory markers and release them in response to moisture or over an extended period of time. The controlled release system of the present invention consists of oil absorbing polymer nanospheres coated with water sensitive surface active polymers.

Priority: US2004-0003869 Applic. Date: 2004-12-03; US2003-0528922P Applic. Date: 2003-12-11

Inventor: LAU WILLIE (US); SCHWARTZ CURTIS (US); SHEFER ADI (US)


Publication No.: US Appl: 20050175649 A1 Published: 2005-08-11

Title: Enhancing properties by the use of nanoparticles

Application No.: US2004-0979365 Applic. Date: 2004-11-01

Abstract: Composite materials comprising nanoparticles functionalized with metals are disclosed. The composite materials may be used in a variety of applications, including in coating compositions, cosmetic and pharmaceutical compositions, absorbent articles, and the like.

Priority: US2004-0979365 Applic. Date: 2004-11-01; US2003-0515758P Applic. Date: 2003-10-30

Inventor: DISALVO ANTHONY L (US); MORDAS CAROLYN J (US)


Publication No.: US Appl: 20050186233 A1 Published: 2005-08-25
Patent No.: US7585514B2 Issued: 2009-09-08

Title: Administration of agents mimicking dopachrome tautomerase (TRP-2) activity for protecting hair follicle melanocytes

Applicant: OREAL (FR)

Application No.: US2004-0009153 Applic. Date: 2004-12-13

Abstract: Agents mimicking DOPAchrome tautomerase activity are administered, notably topically applied, to protect and/or regenerate the melanocytes of hair follicles, to promote the cyclic renewal of the follicular pigmentation unit, to prevent and/or limit and/or arrest the development of canities, and to maintain the natural pigmentation of gray or white head hair and/or body hair.

Priority: US2004-0009153 Applic. Date: 2004-12-13; FR2002-0007137 Applic. Date: 2002-06-11; WO2003-FR01729 Applic. Date: 2003-06-10

Inventor: COMMO STEPHANE (FR); GAILLARD OLIVIER (FR); BERNARD BRUNO (FR)


Publication No.: US Appl: 20050208086 A1 Published: 2005-09-22

Title: Administration of agents inducing DOPAchrome tautomerase (TRP-2) expression for protecting hair follicle melanocytes

Application No.: US2004-0009364 Applic. Date: 2004-12-13

Abstract: Agents inducing the expression of DOPAchrome tautomerase are administered, notably topically applied, to protect and/or regenerate the melanocytes of hair follicles, to promote the cyclic renewal of the follicular pigmentation unit, to prevent and/or limit and/or arrest the development of canities, and to maintain the natural pigmentation of gray or white head hair and/or body hair.

Priority: US2004-0009364 Applic. Date: 2004-12-13; FR2002-0007136 Applic. Date: 2002-06-11; WO2003-FR01728 Applic. Date: 2003-06-10

Inventor: COMMO STEPHANE (FR); BERNARD BRUNO (FR)


Publication No.: US Appl: 20050222071 A1 Published: 2005-10-06

Title: Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA)

Applicant: OREAL (FR)

Application No.: US2004-0001085 Applic. Date: 2004-12-02

Abstract: Expression of a messenger RNA which encodes a protein which is expressed by differentiated cells, notably the cells of the skin or appendages thereof, is inhibited by topically administering to said differentiated cells a thus effective amount of at least one double-stranded RNA oligonucleotide, formulated into a topically applicable, physiologically acceptable medium therefor; such regime or regimen is useful for treating a variety of afflictions or conditions, e.g., combating the signs of skin aging, stimulating hair growth or retarding loss thereof, inhibiting cellular proliferation and/or differentiation, etc.

Priority: FR2002-0006796 Applic. Date: 2002-06-03; WO2003-FR01648 Applic. Date: 2003-06-02

Inventor: DURANTON ALBERT (FR); COLLIN-DJANGONE CHRISTINE (FR); PRUCHE FRANCIS (FR); SIMONNET JEAN-THIERRY (FR)


Publication No.: US Appl: 20050232955 A1 Published: 2005-10-20

Title: Cosmetic compositions containing small magnetic particles

Applicant: DEAD SEA LAB LTD

Application No.: US2004-0519387 Applic. Date: 2004-12-27

Abstract: The present invention present a novel and cost-effective family of cosmetic compositions comprising inter alia small magnetic particles characterized by magnetic field adapted to be topically administrated adjacent to skin surface, absorbed to epidermal upper skin layers and place in a direct contact to the body, usually above pain suffering regions. The present invention also provides the use of the compositions, especially of nano-powders of salts obtained from the Dead Sea, as an external layer of bandages, dressings, compresses or warps, so constantly approached to be in an intimate contact with the patient's skin.

Priority: US2002-0390370P Applic. Date: 2002-06-24; WO2003-IL00529 Applic. Date: 2003-06-23; US2004-0519387 Applic. Date: 2004-12-27

Inventor: MAOR ZEEV (IL); ROYZ MICHAEL (IL)


Publication No.: US Appl: 20050238608 A1 Published: 2005-10-27
Patent No.: US7279542B2 Issued: 2007-10-09

Title: Polymeric particles and fragrance delivery systems

Applicant: FIRMENICH & CIE (CH)

Application No.: US2005-0147632 Applic. Date: 2005-06-07

Abstract: Polymeric micro- and nano-capsules formed of a spherical single hydrophobic polymer, chemically functionalised at their surface so as to comprise hydrophilic moieties thereon are disclosed. The capsules are susceptible of absorbing a perfume and of being optionally coated with an amphiphilic copolymer. They allow the preparation of perfume delivery systems, which provide a slow release of perfuming materials while improving the substantivity of the perfume on a substrate.

Priority: EP2003-0001871 Applic. Date: 2003-01-29; WO2004-IB00200 Applic. Date: 2004-01-22

Inventor: OUALI LAHOUSSINE (FR); LATRECHE DJAMILA (FR)


Publication No.: US Appl: 20050255057 A1 Published: 2005-11-17
Patent No.: US7182938B2 Issued: 2007-02-27

Title: Cosmetic formulations comprising ZnO nanoparticles

Applicant: BASF AG (DE)

Application No.: US2005-0074760 Applic. Date: 2005-03-09

Abstract: The present invention relates to the formation of surface treated zinc oxide and titania particles, and in particular zinc oxide and titania nanoparticles, with a siloxane star-graft copolymer coating, comprising a looped and/or linear polymeric structure on a star-graft copolymer coating, on a particle surface to control the interfacial surface interactions between the particle and the oil phase of the cosmetic skin formulation.

Priority: US2005-0074760 Applic. Date: 2005-03-09; US2004-0592133P Applic. Date: 2004-07-30; US2004-0559857P Applic. Date: 2004-04-06

Inventor: ANDRE VALERIE (DE); BROTZMAN RICHARD W JR (US); BROTZMAN JR RICHARD W (US)


Publication No.: US Appl: 20050283004 A1 Published: 2005-12-22

Title: Alkylsulfonated polyaminosaccharides

Applicant: HOPAX CHEMICALS MFG CO LTD

Application No.: US2004-0871890 Applic. Date: 2004-06-18

Abstract: Alkylsulfonated polyaminosaccharides, such as alkylsulfonated chitosan, having a sultone substituent covalently bonded to the amino group and a known size and degree of substitution may be produced by methods of the invention. Such methods may include heating of the polyaminosaccharide in a polar solvent, such as alcohol, ether, or alcoholether to reflux, then adding an alkyl sultone. Alkylsulfonated polyaminosaccharides of the present invention may be used in a wide variety of applications. Alkylsulfonated chitosan is particularly useful in wound healing.

Priority: US2004-0871890 Applic. Date: 2004-06-18

Inventor: WEI I-CHIEN (TW); LEE KUNG-HSING (TW); HUNG HSIEN-MING (TW)


Publication No.: US Appl: 20060024257 A1 Published: 2006-02-02

Title: Self-molding permanent agent and method for proceeding free-rod and free-band type permanent

Application No.: US2005-0192287 Applic. Date: 2005-07-29

Abstract: The present invention relates to a self-molding permanent agent and a method for proceeding free-rod and free-band type permanent, more particularly to a self-molding permanent agent comprising (a) a reducing composition containing a reducing agent reducing a disulfide bond of cystine on the hair and a molding stimulant spontaneously molding to fix a hair design; (b) a molding composition inducing to mold after reacting with the molding stimulant; and (c) a softening composition releasing the action of a molding stimulant, and a method for pressing a free-rod and free-band type permanent, which overcomes a disadvantage in the conventional method for pressing a permanent that needs to wear a curling device such as rods for a permanent (perm rod) or rubber band and improves to apply a wave set without a hair-curling device for a short time, since it has a self-molding feature.

Priority: KR2004-0060543 Applic. Date: 2004-07-30; KR2004-0060544 Applic. Date: 2004-07-30

Inventor: CHANG TAE S (KR); LEE DONG K (KR); KIM TAE S (KR); WOO WAN J (KR)


Publication No.: US Appl: 20060034786 A1 Published: 2006-02-16

Title: Inhibitors of 15-hydroxyprostaglandin dehydrogenase for stimulating pigmentation of the skin or skin appendages

Applicant: OREAL (FR)

Application No.: US2005-0202192 Applic. Date: 2005-08-12

Abstract: Inhibitors of 15-hydroxyprostaglandin dehydrogenase (15-PGDH), for example tetrazole, styrylpyrazole, phenylfuran, phenylthiophene, phenylpyrrazole, pyrazolecarboxamide, 2-thioacetamide and azo compounds, are useful for promoting or stimulating pigmentation of the skin and/or skin appendages and/or for preventing and/or for limiting depigmentation and/or whitening of the skin and/or skin appendages, notably for preventing and/or limiting canities.

Priority: FR2003-0050023 Applic. Date: 2003-02-12; WO2004-FR00325 Applic. Date: 2004-02-12

Inventor: MICHELET JEAN-FRANCOIS (FR); COMMO STEPHANE (FR)


Publication No.: US Appl: 20060110343 A1 Published: 2006-05-25

Title: Cosmetic or dermopharmaceutical compositions comprising tyramine derivatives, method for preparing same, and use thereof

Applicant: SEDERMA SAS (FR)

Application No.: US2005-0519118 Applic. Date: 2005-09-29

Abstract: The invention concerns cosmetic or dermopharmaceutical compositions comprising tyramine derivatives and their salts. The invention also concerns the method for preparing same and use thereof for reducing pigmaentation.

Priority: FR2002-0007965 Applic. Date: 2002-06-26; WO2003-FR01950 Applic. Date: 2003-06-25

Inventor: LINTNER KARL (FR)


Publication No.: US Appl: 20060110413 A1 Published: 2006-05-25
Patent No.: US7354926B2 Issued: 2008-04-08

Title: Novel Molecules dervied from noraporphine

Applicant: SEDERMA SAS (FR)

Application No.: US2005-0525985 Applic. Date: 2005-09-15

Abstract: The invention concerns novel molecules derived from noraporphine, as well as cosmetic and dermopharmaceutical compositions containing one or several of said derivatives, alone or combined with a plant extract, in particular glaucium flavum, and particularly preparations for reducing pigmentation, with anti-ageing effect or for slimming.

Priority: FR2002-0010810 Applic. Date: 2002-08-30; WO2003-FR02400 Applic. Date: 2003-07-29

Inventor: LINTNER KARL (FR)


Publication No.: US Appl: 20060134029 A1 Published: 2006-06-22
Patent No.: US7341734B2 Issued: 2008-03-11

Title: Personal care compositions comprising semiconductor nanocrystals and methods of making and using the same

Applicant: EVIDENT TECHNOLOGIES (US)

Application No.: US2005-0283903 Applic. Date: 2005-11-22

Abstract: A personal care composition that includes a personal care ingredient and semiconductor nanocrystals. A method of protecting at least a portion of a body against ultraviolet radiation by applying a personal care composition is also provided.

Priority: US2005-0283903 Applic. Date: 2005-11-22; US2004-0630177P Applic. Date: 2004-11-23

Inventor: GILLIES JENNIFER (US); HINES MARGARET (US)


Publication No.: US Appl: 20060165643 A1 Published: 2006-07-27

Title: Cosmetic or dermopharmaceutical compositions containing kombucha

Application No.: US2005-0523333 Applic. Date: 2005-08-29

Abstract: Cosmetic or dermopharmaceutical compositions which contain kombucha are disclosed. The present invention further relates to the use of kombucha and cosmetic or dermopharmaceutical compositions containing the same, alone or in combination, for the care of the skin, mucosae and skin appendages, and in particular for preventing the signs of endogenous and/or exogenous ageing.

Priority: FR2002-0009710 Applic. Date: 2002-07-30; WO2003-FR02368 Applic. Date: 2003-07-25

Inventor: LINTNER KARL (FR)


Publication No.: US Appl: 20060182770 A1 Published: 2006-08-17
Patent No.: US7300649B2 Issued: 2007-11-27

Title: COSMETIC AND COSMECEUTICAL COMPOSITIONS FOR RESTORATION OF SKIN BARRIER FUNCTION

Applicant: GENEPHARM INC (US)

Application No.: US2006-0275994 Applic. Date: 2006-02-08

Abstract: Compositions, kits and methods are provided for restoring skin barrier function to skin exposed to environmental elements and/or in a pathological condition. In general, divalent cations such as calcium ions and/or magnesium ions are included in a physiologically acceptable medium. In some embodiments, divalent cations are balanced with monovalent cations such as sodium and potassium ions at appropriate ratios in order to maintain the homeostasis of skin barrier. The compositions, kits and methods can be used as cosmetics, cosmeceuticals or pharmaceuticals for improving skin condition, and preventing or treating dermatological diseases and skin disorders.

Priority: US2006-0275994 Applic. Date: 2006-02-08; US2005-0652196P Applic. Date: 2005-02-11

Inventor: TANOJO HANAFI (US); HUANG XINFAN (US)


Publication No.: US Appl: 20060260627 A1 Published: 2006-11-23

Title: Wig comprising cap with nano-silver

Applicant: PT DONGAN KREASI INDONESIA (ID)

Application No.: US2005-0190929 Applic. Date: 2005-07-28

Abstract: Disclosed herein is a wig comprising cap with nano-silver that exhibits antibacterial activity. The wig comprising cap with nano-silver of the current invention exhibits antibacterial and disinfecting effects on the hair and scalp of a wearer, by applying the net and lace each formed of fibers with nano-silver to the cap of the wig, and/or by applying nano-silver to the hair of the wig. Thus, when wearing the wig of the current invention, the scalp of the wearer may be kept healthy, and the occurrence of skin diseases due to bacteria maybe prevented.

Priority: KR2005-0042320 Applic. Date: 2005-05-20

Inventor: PARK HUN S (KR)


Publication No.: US Appl: 20060263898 A1 Published: 2006-11-23

Title: Perfume delivery systems based on inorganic nano particles

Application No.: US2006-0416493 Applic. Date: 2006-05-01

Abstract: Nano-sized delivery systems consisting of an inorganic nano particle moiety covalently bonded to at least one organic pro-perfume or pro-drug moiety are disclosed. The systems of the invention are able to deliver perfuming or pharmaceutical active ingredients. Other aspects of the present invention include the use of such systems in perfumery as well as the perfuming compositions or perfumed articles that incorporate these delivery systems.

Priority: WO2003-IB04786 Applic. Date: 2003-10-29; WO2004-IB03539 Applic. Date: 2004-10-27

Inventor: PAGET WALTER (CH); GRATHER OTTO (CH); NONNINGER RALPH (DE); GOEBBERT CHRISTIAN (DE); WITTMER RAINER (DE)


Publication No.: US Appl: 20060264804 A1 Published: 2006-11-23

Title: Device and kit for delivery of encapsulated substances and methods of use thereof

Application No.: US2006-0397864 Applic. Date: 2006-04-05

Abstract: The present invention is of a kit and electricity generating device for delivery of an encapsulated composition or mixture of compositions, including an electricity generating device and at least one composition in an encapsulated carrier vehicle which is contacted or applied to the electricity generating device. In some embodiments the device includes a means for maintaining stability of the encapsulated composition prior to bio-membrane penetration. The present invention also provides methods of use thereof. Furthermore, the present invention provides a device and method for delivering a fixed ratio of compounds from a mixture to a bio-membrane comprising the step of electro-transporting an encapsulated mixture of compounds. Still further, the present invention is of a device and method for delivering each compound of a mixture of compounds to the same penetration depth.

Priority: US2006-0397864 Applic. Date: 2006-04-05; US2005-0669001P Applic. Date: 2005-04-07

Inventor: KARMON YORAM (IL); HAREL NURIT (IL); MAVOR DANIELA (IL); SHAHAR MICHAL (IL)


Publication No.: US Appl: 20070043109 A1 Published: 2007-02-22

Title: Slimming cosmetic composition

Applicant: SEDERMA SAS (FR)

Application No.: US2004-0557616 Applic. Date: 2004-05-19

Abstract: Cosmetic or dermopharmaceutical compositions containing, in a dermatologically acceptable carrier, at least one diterpene among: cafestol, kahweol and chemical derivatives are useful for slimming treatments including prevent and/or treat cellulite or orange peel and/or to refine contours of the face, skin firming, to reduce the steatomery of the thighs, to decrease the volume/fatty overload of the spare tire at the hips, to reduce "love handles", both on men and women.

Priority: FR2003-0006063 Applic. Date: 2003-05-20; JP2004-0052321 Applic. Date: 2004-02-26; WO2004-IB50755 Applic. Date: 2004-05-19

Inventor: LINTER KARL (FR); MAS CHAMBERLIN CLAIRE (FR)


Publication No.: US Appl: 20070135335 A1 Published: 2007-06-14

Title: Therapeutic molecules

Applicant: UNIV DEAKIN (AU)

Application No.: US2004-0545099 Applic. Date: 2004-02-10

Abstract: The present invention relates generally to a ligand for a protein associated with modulating obesity, diabetes and metabolic energy levels in animals including humans. More particularly, the present invention provides a ligand of the protein, Beacon, and its homologs. The identification of a Beacon ligand permits the identification of agents which agonize or antagonize the Beacon-ligand interaction and, hence, the development of therapeutic molecules useful in modulating obesity, diabetes and/or energy imbalance.

Priority: US2004-0545099 Applic. Date: 2004-02-10; US2003-0446191P Applic. Date: 2003-02-10; WO2004-AU00147 Applic. Date: 2004-02-10

Inventor: COLLIER GREG (AU); WALDER KEN (AU); KERR-BAYLES LYNDAL (AU)


Publication No.: US Appl: 20070140951 A1 Published: 2007-06-21

Title: Nano-sized particles, processes of making, compositions and uses thereof

Applicant: UNIV COLUMBIA (US)

Application No.: US2006-0451251 Applic. Date: 2006-06-12

Abstract: The present invention describes methods for preparing high quality nanoparticles, i.e., metal oxide based nanoparticles of uniform size and monodispersity. The nanoparticles advantageously comprise organic alkyl chain capping groups and are stable in air and in nonpolar solvents. The methods of the invention provide a simple and reproducible procedure for forming transition metal oxide nanocrystals, with yields over 80%. The highly crystalline and monodisperse nanocrystals are obtained directly without further size selection; particle size can be easily and fractionally increased by the methods. The resulting nanoparticles can exhibit magnetic and/or optical properties. These properties result from the methods used to prepare them.; Also advantageously, the nanoparticles of this invention are well suited for use in a variety of industrial applications, including cosmetic and pharmaceutical formulations and compositions.

Priority: US2006-0451251 Applic. Date: 2006-06-12; WO2004-US41141 Applic. Date: 2004-12-09; US2003-0528667P Applic. Date: 2003-12-11

Inventor: O'BRIEN STEPHEN (US); YIN MING (US)


Publication No.: US Appl: 20070148634 A1 Published: 2007-06-28

Title: CELLS HAVING A SPECTRAL SIGNATURE AND METHODS OF PREPARATIONS AND USE THEREOF

Applicant: INVITROGEN CORP (US)

Application No.: US2007-0682063 Applic. Date: 2007-03-05

Abstract: Methods, compositions and articles of manufacture for encoding a cell with semiconductor nanocrystals and/or other fluorophors are provided. The encoded cells can be subjected to functional assays in mixed populations, and an assay result can be determined and associated with individual cells by virtue of their code. The methods are particularly useful in multiplex settings where a plurality of encoded cells are to be assayed.

Priority: US2007-0682063 Applic. Date: 2007-03-05; US2001-0972744 Applic. Date: 2001-10-05; US2000-0238677P Applic. Date: 2000-10-06; US2001-0312558P Applic. Date: 2001-08-15

Inventor: BRUCHEZ MARCEL P (US); DANIELS R H (US); DIAS JENNIFER (US); MATTHEAKIS LARRY C (US); LIU JIANQUAN (US)


Publication No.: US Appl: 20070207101 A1 Published: 2007-09-06

Title: Cosmetic Compositions Comprising Sub-micron Boron Nitride Particles

Applicant: GEN ELECTRIC (US)

Application No.: US2006-0554004 Applic. Date: 2006-10-28

Abstract: A cosmetic composition for use on hair, skin or nails, containing a safe and effective amount of boron nitride powder has been found which improves the appearance of skin by blurring lines and wrinkles while at the same time providing coverage of age spots, blemishes and other discolorations.

Priority: US2006-0554004 Applic. Date: 2006-10-28; US2006-0777917P Applic. Date: 2006-03-01

Inventor: BUTTS MATTHEW (US); SINHA MOITREYEE (US); GENOVESE SARAH ELIZABETH (US); YAMADA MASAKO (US)


Publication No.: US Appl: 20070286856 A1 Published: 2007-12-13
Patent No.: US7662929B2 Issued: 2010-02-16

Title: Modulation of Hyaluronan Synthesis and Degradation in the Treatment of Disease

Applicant: ALCHEMIA ONCOLOGY LTD (AU); ALCHEMIA ONCOLOGY PTY LTD (AU)

Application No.: US2004-0574903 Applic. Date: 2004-10-11

Abstract: The present invention provides compositions and methods for modulating the expression of Hyaluronan (HA). In particular, this invention relates to compounds, which hybridize with nucleic acid molecules encoding hyaluronan synthase (HAS), particularly HAS isoforms HAS1, HAS2 and HAS3. These compounds may range in size from oligonucleotides to full length sequences. Such compounds are exemplified to modulate proliferation, such as cancer and inflammatory disorders, such as arthritis. It will be understood, however, that the compounds can be used for any other condition in which HA is involved.

Priority: AU2003-0905551 Applic. Date: 2003-10-10; AU2003-0906658 Applic. Date: 2003-12-01; WO2004-AU01383 Applic. Date: 2004-10-11

Inventor: BROWN TRACEY J (AU); BROWNLEE GARY R (AU)


Publication No.: US Appl: 20080014229 A1 Published: 2008-01-17

Title: Administration of compounds that increase glutathione levels in the melanocytes for the treatment of canities

Applicant: OREAL (FR)

Application No.: US2007-0812900 Applic. Date: 2007-06-22

Abstract: At least one compound that increases the level of glutathione (GSH) in the melanocytes of hair follicles, and admixtures thereof with other active agents selected from among active agents for combating desquamative conditions of the scalp, plant extracts having propigmenting activity and active agents that slow hair loss and/or promote hair regrowth, are useful for preventing and/or limiting and/or stopping the development of canities.

Priority: FR2004-0013756 Applic. Date: 2004-12-22; WO2005-FR03196 Applic. Date: 2005-12-20

Inventor: COMMO STEPHANE (FR)


Publication No.: US Appl: 20080026018 A1 Published: 2008-01-31

Title: Administration of coumarin, butylated hydroxyanisole and ethoxyquine for the treatment of canities

Applicant: OREAL (FR)

Application No.: US2007-0812571 Applic. Date: 2007-06-20

Abstract: At least one compound selected from among coumarin and/or derivative thereof, butylated hydroxyanisole, ethoxyquine and mixtures thereof, and admixtures thereof with other active agents selected from among active agents for combating desquamative conditions of the scalp, plant extracts having propigmenting activity and active agents that slow hair loss and/or promote hair regrowth, are useful for preventing and/or limiting and/or stopping the development of canities.

Priority: US2007-0812571 Applic. Date: 2007-06-20; FR2006-0052556 Applic. Date: 2006-06-20; US2006-0819399P Applic. Date: 2006-07-10

Inventor: COMMO STEPHANE (FR)


Publication No.: US Appl: 20080026019 A1 Published: 2008-01-31

Title: Administration of ellagic acid for the treatment of canities

Applicant: OREAL (FR)

Application No.: US2007-0812572 Applic. Date: 2007-06-20

Abstract: At least one compound selected from among ellagic acid, its salts, its metal complexes, its monoether or polyether, monoacylated or polyacylated derivatives and its carbonate or carbamate derivatives deriving from hydroxyl groups and mixtures thereof, and admixtures thereof with other active agents selected from among active agents for combating desquamative conditions of the scalp, plant extracts having propigmenting activity and active agents that slow hair loss and/or promote hair regrowth, are useful for preventing and/or limiting and/or stopping the development of canities.

Priority: US2007-0812572 Applic. Date: 2007-06-20; FR2006-0052552 Applic. Date: 2006-06-20; US2006-0819398P Applic. Date: 2006-07-10

Inventor: COMMO STEPHANE (FR)


Publication No.: US Appl: 20080027129 A1 Published: 2008-01-31

Title: Administration of 3H-1, 2-dithiole-3-thione, anethole dithiolethione, sulforaphane, phenethyl isothiocyanate, 6-(methylsulfinyl)hexyl isothiocyanate and allyl isothiocyanate for the treatment of canities

Applicant: OREAL (FR)

Application No.: US2007-0812573 Applic. Date: 2007-06-20

Abstract: At least one compound selected from among 3H-1,2-dithiole-3-thione, anethole dithiolethione, sulforaphane, phenethyl isothiocyanate, 6-(methylsulfinyl)hexyl isothiocyanate and allyl isothiocyanate and derivatives and mixtures thereof, and admixtures thereof with other active agents selected from among active agents for combating desquamative conditions of the scalp, plant extracts having propigmenting activity and active agents that slow hair loss and/or promote hair regrowth, are useful for preventing and/or limiting and/or stopping the development of canities.

Priority: US2007-0812573 Applic. Date: 2007-06-20; FR2006-0052555 Applic. Date: 2006-06-20; US2006-0819397P Applic. Date: 2006-07-10

Inventor: COMMO STEPHANE (FR)


Publication No.: US Appl: 20080044444 A1 Published: 2008-02-21

Title: Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof

Applicant: FOAMIX LTD (IL)

Application No.: US2007-0825406 Applic. Date: 2007-07-05

Abstract: The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.

Priority: US2007-0825406 Applic. Date: 2007-07-05; IL2002-0152486 Applic. Date: 2002-10-25; US2005-0532618 Applic. Date: 2005-12-22; WO2003-IB05527 Applic. Date: 2003-10-24; US2005-0078902 Applic. Date: 2005-03-11; US2007-0717897 Applic. Date: 2007-03-13; US2007-0653205 Applic. Date: 2007-01-12; US2004-0835505 Applic. Date: 2004-04-28; US2004-0911367 Applic. Date: 2004-08-04; US2006-0818634P Applic. Date: 2006-07-05; US2002-0429546P Applic. Date: 2002-11-29; US2003-0492385P Applic. Date: 2003-08-04; US2003-0530015P Applic. Date: 2003-12-16

Inventor: TAMARKIN DOV (IL); FRIEDMAN DORON (IL); BERMAN TAL (IL); ZIV ENBAL (IL); SCHUZ DAVID (IL)


Publication No.: US Appl: 20080092915 A1 Published: 2008-04-24

Title: Hair Styling Apparatus

Applicant: DICKSON IND CO LTD (CN)

Application No.: US2005-0660267 Applic. Date: 2005-08-15

Abstract: A hair styling apparatus comprising a handle and a hair styling member with a transparent window. The transparent window has substantially transparent electric heating substances which are distributed along the hair styling member.

Priority: HK2004-0106152 Applic. Date: 2004-08-17; WO2005-IB02426 Applic. Date: 2005-08-15

Inventor: CHAN WING K (CN)


Publication No.: US Appl: 20080115846 A1 Published: 2008-05-22

Title: Aqueous fluid photoprotective compositions comprising ester-terminated poly(ester amide) polymers

Applicant: OREAL (FR)

Application No.: US2007-0653868 Applic. Date: 2007-01-17

Abstract: Enhanced SPF and/or reduced fluffing fluid compositions for photoprotecting the skin and/or the hair against the damaging effects of ultraviolet radiation, contain: (a) at least one photoprotective system capable of screening out UV radiation; and (b) at least one ester-terminated poly(ester amide) (ETPEA) polymer, formulated into (c) a topically applicable, cosmetically acceptable aqueous support therefor; the subject aqueous compositions are advantageously vaporizable, especially in the form of sprays, confined within a pressurization device.

Priority: US2007-0653868 Applic. Date: 2007-01-17; FR2006-0050192 Applic. Date: 2006-01-19; US2006-0762127P Applic. Date: 2006-01-26

Inventor: JOSSO MARTIN (FR); CHEVALIER CYRIL (FR); GAUDRY ANNE-LAURE (FR)


Publication No.: US Appl: 20080135245 A1 Published: 2008-06-12

Title: Composition and Method For Making a Proppant

Applicant: OXANE MATERIALS INC (US)

Application No.: US2007-0769247 Applic. Date: 2007-06-27

Abstract: The present invention relates to proppants which can be used to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more proppants of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the proppants of the present invention are further disclosed, as well as methods of making the proppants.

Priority: US2007-0769247 Applic. Date: 2007-06-27; US2007-0728953 Applic. Date: 2007-03-27; US2006-0498527 Applic. Date: 2006-08-03; US2006-0347664 Applic. Date: 2006-02-03; US2005-0649594P Applic. Date: 2005-02-04

Inventor: SMITH RUSSELL J (US); LOSCUTOVA JOHN R (US); COKER CHRISTOPHER E (US); BARRON ANDREW R (US); SKALA ROBERT D (US); WHITSITT ELIZABETH A (US); WIESNER MARK (US); COSTANTINO STEPHEN A (US); BORDIA RAJENDRA (US)


Publication No.: US Appl: 20080138296 A1 Published: 2008-06-12

Title: Foam prepared from nanoemulsions and uses

Applicant: FOAMIX LTD (IL)

Application No.: US2007-0975621 Applic. Date: 2007-10-19

Abstract: The present invention provides a foamable composition for administration to the skin, body surface, body cavity or mucosal surface, e.g., the mucosa of the nose, mouth, eye, ear, respiratory system, vagina or rectum. The foamable oil in water nano emulsion composition includes: (a) a nano oil globule system, comprising substantially of sub-micron oil globules; (b) about 0.1% to about 5% by weight of at least one stabilizing agent, selected from the group consisting of (i) a non-ionic surfactant, (ii) an ionic surfactant, and (iii) a polymeric agent; and (c) a liquefied or compressed gas propellant at a concentration of about 3% to about 25% by weight of the total composition, water and optional ingredients are added to complete the total mass to 100%. Upon release from an aerosol container, the foamable composition forms and expanded foam suitable for topical administration.; The present invention further provides methods of treating, alleviating or preventing a disorder of the skin, body cavity or mucosal surface using such foamable compositions; and to methods of producing such foams having an improved bubble size.

Priority: US2007-0975621 Applic. Date: 2007-10-19; IL2002-0152486 Applic. Date: 2002-10-25; US2006-0389742 Applic. Date: 2006-03-27; US2004-0911367 Applic. Date: 2004-08-04; US2005-0532618 Applic. Date: 2005-12-22; WO2003-IB05527 Applic. Date: 2003-10-24; US2003-0492385P Applic. Date: 2003-08-04; US2005-0717058P Applic. Date: 2005-09-14; US2002-0429546P Applic. Date: 2002-11-29

Inventor: TAMARKIN DOV (IL); BESONOV ALEX (IL); EINI MEIR (IL); DANZIGER JORGE (IL)


Publication No.: US Appl: 20080138379 A1 Published: 2008-06-12

Title: Methods, treatments, and compositions for modulating Hedgehog pathways

Application No.: US2007-0001869 Applic. Date: 2007-12-13

Abstract: The present invention relates to prevention of congenital deformations The invention further relates to cancer inhibition and prevention. The invention further relates to methods and compositions to modulate, antagonize, or agonize disparate signaling pathways that may converge to regulate patterning events gene expression during prenatal development, post-natal development and during development in the adult organism.

Priority: US2007-0001869 Applic. Date: 2007-12-13; US2006-0591398 Applic. Date: 2006-11-01

Inventor: JENNINGS-SPRING BARBARA L (US)


Publication No.: US Appl: 20080166303 A1 Published: 2008-07-10

Title: Colored or colorable foamable composition and foam

Application No.: US2007-0900328 Applic. Date: 2007-09-10

Abstract: There is described a colored or colorable topical composition, comprising: a) a foamable base composition comprising, 1) a flowable carrier composition; 2) a color agent; wherein the color agent is effective to impart, increase, decrease or otherwise affect color of a foam produced from the foamable composition and wherein the color agent is one or more agents selected from the group consisting of a colored active agent, a colored indicator, a colored excipient, a pigment, a dye, a colorant and a coloring agent; b) a propellant at a concentration of about 3% to about 25% by weight of the total composition; wherein the base composition has a first color; and wherein the foam comprising the colored or colorable topical composition has a second color upon dispensing from an aerosol container, and wherein the first color and the second color are visually different.; There is also described a method of changing color, a method of administration, a use as a diagnostic and a kit.

Priority: US2007-0900328 Applic. Date: 2007-09-10; US2006-0843144P Applic. Date: 2006-09-08

Inventor: TAMARKIN DOV (IL); FRIEDMAN DORON (IL); EINI MEIR (IL)


Publication No.: US Appl: 20080183250 A1 Published: 2008-07-31

Title: Compositions and methods for treating or preventing skin inflammation via restoration of skin barrier function

Application No.: US2007-0985806 Applic. Date: 2007-11-16

Abstract: Compositions, kits and methods are provided for restoring skin barrier function to skin of a subject after a medical or a cosmetic procedure. In general, a composition containing divalent cations such as calcium ions and/or magnesium ions in a physiologically acceptable medium can be used to treat, inhibit or prevent inflammation of skin post medical, demertological, or cosmetic procedure such as chemical peeling, laser skin resurfacing, microdermabrasion, plasma energy treatment, radiofrequency treatment, hair or vein removal or lightening, skin treatment using light energy or photofacial, thereby treating, inhibiting or preventing post-inflammatory hyperpigmentation of the skin or other skin disorders.

Priority: US2007-0985806 Applic. Date: 2007-11-16; US2006-0275994 Applic. Date: 2006-02-08; US2005-0652196P Applic. Date: 2005-02-11

Inventor: TANOJO HANAFI (US); HUANG XINFAN (US)


Publication No.: US Appl: 20080199503 A1 Published: 2008-08-21

Title: Pharmaceutical Compositions Preparation of Peptides, Secreted by the Snake Venom Glands, Particularly of Bothrops Jararaca, Vasopeptidases Inhibitors, Evasins, Their Analogues, Derivatives and Products Associated, Thereof, for Development of Applications and Use in Chronic-Degenerative Diseases

Applicant: BIOLAB SANUS FARMACEUTICA LTD (BR)

Application No.: US2003-0537264 Applic. Date: 2003-12-09

Abstract: The present invention is characterized by the process of preparation of pharmaceutical compositions for the development of applications of the Evasins and their structural and/or conformational analogues in chronic-degenerative diseases. It is further characterized by the process of preparation of pharmaceutical compositions and related products of the Evasins peptides and their structural and/or conformational analogues in using the cyclodextrins, its derivatives, liposomes and biodegradable polymers and/or mixture of these systems. The invention is further characterized by the increased efficacy of these peptides and their analogues included in cyclodextrins, when administered to rats. This characterizes an increased biodisponibility of these peptides and their analogues using the compositions of the present invention.

Priority: BR2002-0005449 Applic. Date: 2002-12-09; WO2003-BR00192 Applic. Date: 2003-12-09

Inventor: CAMARGO ANTONIO (BR); SANTOS ROBSON (BR); MILLAN RUBEN (BR); IANZER DANIELLE (BR); HAYASHI MIRIAN (BR)


Publication No.: US Appl: 20080206320 A1 Published: 2008-08-28

Title: COMPOSITION COMPRISING AT LEAST ONE 15-PGDH INHIBITOR

Applicant: OREAL (FR)

Application No.: US2007-0940909 Applic. Date: 2007-11-15

Abstract: The invention relates to a cosmetic composition containing at least one 15-hydroxy-prostaglandin dehydrogenase inhibitor and cosmetically acceptable excipients. It also relates to a method of cosmetic treatment for promoting the growth and/or preventing or delaying the loss of hair, and the use of a 15-hydroxyprostaglandin dehydrogenase inhibitor for the preparation of a composition intended for controlling hair loss and/or for promoting hair regrowth.

Priority: US2007-0940909 Applic. Date: 2007-11-15; FR2002-0005067 Applic. Date: 2002-04-23; FR2002-0013461 Applic. Date: 2002-10-28; US2003-0420831 Applic. Date: 2003-04-23; US2002-0387420P Applic. Date: 2002-06-11; US2002-0425330P Applic. Date: 2002-11-12

Inventor: MICHELET JEAN-FRANCOIS (FR); BERNARD BRUNO (FR); ROZOT ROGER (FR); BOULLE CHRISTOPHE (FR)


Publication No.: US Appl: 20080206349 A1 Published: 2008-08-28

Title: Spray Dried Compositions

Application No.: US2005-0883215 Applic. Date: 2005-12-20

Abstract: The invention provides a method comprising the steps of: (i) providing an emulsion of: a) an aqueous solvent, such as water, b) a carrier material dispersible or soluble in (a), said carrier material being solid at ambient temperature, and preferably being a polymer and inorganic salt or a surfactant, c) a volatile second liquid phase (for example, chloroform) which is not miscible with (a), and d) a material which is dispersible or soluble in (c) but not in (a), and, (ii) Drying the emulsion at above ambient temperature (preferably by spray drying) to simultaneously remove (a) and (c) and thereby obtain the material (b) in solid form with (d) dispersed therein.

Priority: GB2005-0001835 Applic. Date: 2005-01-28; WO2005-EP13933 Applic. Date: 2005-12-20

Inventor: BARNWELL STEPHEN GEORGE (GB); COOPER ADREW IAN (GB); DUNCALF DAVID JOHN (GB); FOSTER ALISON JAYNE (GB); RANNARD STEVEN PAUL (GB)


Publication No.: US Appl: 20080213198 A1 Published: 2008-09-04

Title: Cosmetic or Dermopharmaceutical Composition Comprising at Least one Udp Glucuronosyl Transferase (Ugt) Enzymes Inducer

Applicant: SEDERMA SAS (FR)

Application No.: US2005-0587533 Applic. Date: 2005-04-25

Abstract: The invention relates to topical use of at least one UGT inducer for the preparation of a cosmetic or dermopharmaceutical composition comprising a dermatologically acceptable carrier to protect and/or enhance the state of the skin and prevent and/or treat imperfections of the skin.

Priority: FR2004-0004408 Applic. Date: 2004-04-26; WO2005-IB51344 Applic. Date: 2005-04-25

Inventor: LINTNER KARL (FR); MAS CHAMBERLIN CLAIRE (FR)


Publication No.: US Appl: 20080213572 A1 Published: 2008-09-04
Patent No.: US7501174B2 Issued: 2009-03-10

Title: HIGH PERFORMANCE GEOSYNTHETIC ARTICLE

Applicant: PRS MEDITERRANEAN LTD (IL)

Application No.: US2007-0680987 Applic. Date: 2007-03-01

Abstract: Geotechnical article, and process for making it, the article having coefficient of thermal expansion less than about 150 ppm/ DEG C. at ambient; resistance to acidic media greater than polyamide 6 resin and/or resistance to basic media greater than PET resin; resistance to hydrocarbons greater than that of HDPE; creep modulus of at least 400 MPa at 25 DEG C., at 20% of yield stress load for 60 minutes (ISO 899-1); and 1 percent secant flexural modulus at least 700 MPa at 25 DEG C. (ASTM D790); the article including a composition including (a) from about 1 to about 95% by weight of the composition of at least one functional group containing polymer or oligomer; and (b) from about 5 to about 99% by weight of the composition of at least one engineering thermoplastic, and optionally containing a filler and optionally containing an unmodified polyolefin, ethylene copolymer or ethylene terpolymer.

Priority: US2007-0680987 Applic. Date: 2007-03-01

Inventor: HALAHMI IZHAR (IL); EREZ ODED (IL); EREZ ADI (IL)


Publication No.: US Appl: 20080226684 A1 Published: 2008-09-18

Title: METHOD AND PROCESS FOR THE PRODUCTION OF MULTI-COATED RECOGNITIVE AND RELEASING SYSTEMS

Applicant: UNIV TEXAS (US)

Application No.: US2008-0047309 Applic. Date: 2008-03-12

Abstract: The present invention includes compositions, methods, systems and kits for the controlled delivery of an active agent within a polymeric network upon the binding of a molecule that decreases the structural integrity of the polymeric network at one or more micro- or nanovacuoles.

Priority: US2008-0047309 Applic. Date: 2008-03-12; US2007-0894451P Applic. Date: 2007-03-12

Inventor: PEPPAS NICHOLAS A (US)


Publication No.: US Appl: 20080317679 A1 Published: 2008-12-25

Title: FOAMABLE COMPOSITIONS AND KITS COMPRISING ONE OR MORE OF A CHANNEL AGENT, A CHOLINERGIC AGENT, A NITRIC OXIDE DONOR, AND RELATED AGENTS AND THEIR USES

Applicant: FOAMIX LTD (IL)

Application No.: US2007-0767442 Applic. Date: 2007-06-22

Abstract: The present invention relates to a foamable therapeutic composition comprising: (a) a therapeutically effective concentration of at least one active agent selected from the group consisting of a channel agent, a cholinergic agent, and a nitric oxide donor; and (b) a foamable carrier comprising: i. about 50% to about 98% of a solvent selected from the group consisting of water; a hydrophilic solvent; a hydrophobic solvent; a potent solvent; a polar solvent, a silicone, an emollient, and mixtures thereof; ii. 0% to about 48% of a secondary solvent selected from the group consisting of water; a hydrophilic solvent; a hydrophobic solvent; a potent solvent; a polar solvent, a silicone, an emollient, a co-solvent, a penetration enhancer and mixtures thereof; iii. a surface-active agent; iv. about 0% to about 5% by weight of at least one polymeric agent; and v. a liquefied or compressed gas propellant at a concentration of about 3% to about 25% by weight of the total composition; wherein the composition is housed in a container and is substantially flowable, and which upon release expands to form a breakable foam; and wherein the foamable carrier is selected to generate a foam of good to excellent quality. The invention further provides a method of treating, alleviating or preventing a disorder of mammalian subject, comprising administering such a composition to an afflicted target site.

Priority: US2007-0767442 Applic. Date: 2007-06-22; IL2002-0152486 Applic. Date: 2002-10-25; US2004-0911367 Applic. Date: 2004-08-04; US2005-0532618 Applic. Date: 2005-12-22; WO2003-IB05527 Applic. Date: 2003-10-24; US2004-0835505 Applic. Date: 2004-04-28; US2006-0430437 Applic. Date: 2006-05-09; US2006-0430599 Applic. Date: 2006-05-09; US2003-0492385P Applic. Date: 2003-08-04; US2002-0429546P Applic. Date: 2002-11-29; US2005-0679020P Applic. Date: 2005-05-09; US2006-0784793P Applic. Date: 2006-03-21; US2003-0530015P Applic. Date: 2003-12-16; US2006-0815948P Applic. Date: 2006-06-23

Inventor: TAMARKIN DOV (IL); EINI MEIR (IL); FRIEDMAN DORON (IL); BERMAN TAL (IL); BESONOV ALEX (IL)


Publication No.: US Appl: 20090010976 A1 Published: 2009-01-08

Title: Cosmetic or dermopharmaceutical compositions containing kombucha

Applicant: SEDERMA (FR)

Application No.: US2008-0231114 Applic. Date: 2008-08-29

Abstract: Cosmetic or dermopharmaceutical compositions which contain kombucha are disclosed. The present invention further relates to the use of kombucha and cosmetic or dermopharmaceutical compositions containing the same, alone or in combination, for the care of the skin, mucosae and skin appendages, and in particular for preventing the signs of endogenous and/or exogenous ageing.

Priority: US2008-0231114 Applic. Date: 2008-08-29; FR2002-0009710 Applic. Date: 2002-07-30; US2005-0523333 Applic. Date: 2005-08-29; WO2003-FR02368 Applic. Date: 2003-07-25

Inventor: LINTNER KARL (FR)


Publication No.: US Appl: 20090017147 A1 Published: 2009-01-15

Title: Cosmetic or Dermopharmaceutical Composition Comprising an Euglena Extract

Applicant: SEDERMA (FR)

Application No.: US2006-0795330 Applic. Date: 2006-01-13

Abstract: The invention provides a cosmetic or dermopharmaceutic composition containing an Euglena extract, its use to activate the cellular metabolism and in particular to protect and/or improve the state of the skin and to reduce the signs of ageing in particular and/or cutaneous fatigue

Priority: FR2005-0000431 Applic. Date: 2005-01-14; WO2006-IB50135 Applic. Date: 2006-01-13

Inventor: LINTNER KARL (FR); MAS CHAMBERLIN CLAIRE (FR); LAMY LOUIS FRANCOIS (FR); MONDON PHILIPPE (FR)


Publication No.: US Appl: 20090112239 A1 Published: 2009-04-30

Title: Sticky dilatation balloon and methods of using

Applicant: SPECIALIZED VASCULAR TECHNOLOG (US)

Application No.: US2008-0262409 Applic. Date: 2008-10-31

Abstract: The present invention involves an expandable element with an outer sticky surface. The expandable element may be in the form of a balloon with deflated and inflated configurations. The expandable element serves to both dilate a lumen in a blood vessel thereby opening it and to exert force upon the sticky surface in order to press it into apposition against a vessel wall. The outer sticky surface may be provided directly upon the expandable element or on a separate outer sheath that conforms to and follows the contours of the expandable element. The sticky surface may take the form of a biochemical composition and/or a mechanically abrasive structure such as microhooks, hairs, mesh netting, etc. Optionally, additional expandable elements may be provided proximal and distal to the main element to occlude blood flow on either side of a lesion in order to better trap emboli for collection.

Priority: US2008-0262409 Applic. Date: 2008-10-31; US2007-0001217P Applic. Date: 2007-10-31; US2007-0002343P Applic. Date: 2007-11-08

Inventor: TO JOHN THAO (US)


Publication No.: US Appl: 20090117063 A1 Published: 2009-05-07

Title: Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA)

Application No.: US2008-0007387 Applic. Date: 2008-01-09

Abstract: Expression of a messenger RNA which encodes a protein which is expressed by differentiated cells, notably the cells of the skin or appendages thereof, is inhibited by topically administering to said differentiated cells a thus effective amount of at least one double-stranded RNA oligonucleotide, formulated into a topically applicable, physiologically acceptable medium therefor; such regime or regimen is useful for treating a variety of afflictions or conditions, e.g., combating the signs of skin aging, stimulating hair growth or retarding loss thereof, inhibiting cellular proliferation and/or differentiation, etc.

Priority: US2008-0007387 Applic. Date: 2008-01-09; FR2002-0006796 Applic. Date: 2002-06-03; US2004-0001085 Applic. Date: 2004-12-02; WO2003-FR01648 Applic. Date: 2003-06-02

Inventor: DURANTON ALBERT (FR); COLLIN-DJANGONE CHRISTINE (FR); PRUCHE FRANCIS (FR); SIMONNET JEAN-THIERRY (FR)


Publication No.: US Appl: 20090149361 A1 Published: 2009-06-11

Title: Personal cleansing kit for promoting relaxation and sleep, reducing stress and decreasing muscle tightness

Application No.: US2007-0001411 Applic. Date: 2007-12-11

Abstract: The present invention relates to a personal cleansing kit, that when used according to the instructions, provides a reduction in stress levels and muscle tightness, and improved sleep and relaxation. In one embodiment the personal cleansing kit comprises an article of commerce, a musical recording; and a heated cream. In another embodiment, the personal cleansing kit comprises an article of commerce an aroma releasing composition and a heated cream. In another embodiment, the personal cleansing kit comprises an article of commerce an aroma releasing composition, a musical recording and a heated cream. The article of commerce comprises a personal cleansing composition contained within a container and a set of instructions in association with said container. The set of instructions includes a breathing step, a stretching step and a massaging step.

Priority: US2007-0001411 Applic. Date: 2007-12-11

Inventor: ADKISON EMILY KATHLEEN (US); BRENNOCK JUNE TURKANIS (US); RODRIGUEZ VICTOR RUBEN (US)


Publication No.: US Appl: 20090156563 A1 Published: 2009-06-18

Title: Glucan Compositions

Application No.: US2006-0085271 Applic. Date: 2006-11-20

Abstract: A cosmetic or pharmaceutical composition is provided comprising: a) 0.001 to less than 0.2% by weight, based on the weight of the total composition, of a scleroglucan having a mean molecular weight of 1x106 to 12x106; b) a cosmetically or pharmaceutically acceptable carrier; and, optionally, c) lactic acid, a lactate and/or pentanediol. The composition shows advantageous effects, such as moisturization of skin or mucosa, and has an antiaging and revitalizing effect on the skin. When combined with a certain bactericide as explained in claim 1, compositions containing native polysaccharides of the glucan class in general, especially of the scleroglucan as of component a), are well suitable to reduce the number of bacteria in mucosal or oral environments and minimise adhesion, while retaining a pleasant feeling on the mucosa or gingiva. Plaque thus can be efficiently prevented or removed.

Priority: EP2005-0111504 Applic. Date: 2005-11-30; EP2006-0116766 Applic. Date: 2006-07-07; WO2006-EP68645 Applic. Date: 2006-11-20

Inventor: BASCHONG WERNER (CH); MONGIAT SEBASTIEN (FR); OCHS DIETMAR (DE)


Publication No.: US Appl: 20090169803 A1 Published: 2009-07-02

Title: HIGH PERFORMANCE GEOSYNTHETIC ARTICLE

Applicant: PRS MEDITERRANEAN LTD (IL)

Application No.: US2009-0397503 Applic. Date: 2009-03-04

Abstract: Geotechnical article, and process for making it, the article having coefficient of thermal expansion less than about 150 ppm/ DEG C. at ambient; resistance to acidic media greater than polyamide 6 resin and/or resistance to basic media greater than PET resin; resistance to hydrocarbons greater than that of HDPE; creep modulus of at least 400 MPa at 25 DEG C., at 20% of yield stress load for 60 minutes (ISO 899-1); and 1 percent secant flexural modulus at least 700 MPa at 25 DEG C. (ASTM D790); the article including a composition including (a) from about 1 to about 95% by weight of the composition of at least one functional group containing polymer or oligomer; and (b) from about 5 to about 99% by weight of the composition of at least one engineering thermoplastic, and optionally containing a filler and optionally containing an unmodified polyolefin, ethylene copolymer or ethylene terpolymer.

Priority: US2009-0397503 Applic. Date: 2009-03-04; US2007-0680987 Applic. Date: 2007-03-01

Inventor: HALAHMI IZHAR (IL); EREZ ODED (IL); EREZ ADI (IL)


Publication No.: US Appl: 20090196912 A1 Published: 2009-08-06

Title: Pyridinylamines

Applicant: GPC BOTECH AG (DE)

Application No.: US2005-0659013 Applic. Date: 2005-08-01

Abstract: Described are pyridinylamines and pharmaceutically acceptable salts thereof, the use of these pyridinylamines for the prophylaxis and/or treatment of various diseases such as infectious diseases, including opportunistic infections, prion diseases immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, as well as pharmaceutical compositions containing at least one pyridinylamine and/or pharmaceutically acceptable salts thereof. Furthermore, reaction procedures for the synthesis of the pyridinylamines are disclosed.

Priority: US2005-0659013 Applic. Date: 2005-08-01; EP2004-0018131 Applic. Date: 2004-07-30; US2004-0599307P Applic. Date: 2004-08-06; WO2005-EP08321 Applic. Date: 2005-08-01

Inventor: EICKHOFF JAN ELKE (DE); HAFENBRADL DORIS (DE); SCHWAB WILFRIED (DE); COTTON MATTHEW (GM); KIEBL BERT MATTHIAS (DE); ZECH BIRGIT (DE); MULLER STEFAN (DE); HARRIS JOHN (GB); SAVIC VLADIMIR (SA); MACRITCHIE JACKIE (GB)


Publication No.: US Appl: 20090202616 A1 Published: 2009-08-13

Title: Composite, Method of Producing the Composite and Uses of the Same

Applicant: UNIV SINGAPORE (SG)

Application No.: US2005-0664164 Applic. Date: 2005-09-29

Abstract: The invention relates to a composite comprising a semi-permeable barrier layer that is permeable to oxygen and impermeable to moisture; and a scaffold fiber layer formed by electrospinning fibers on one side of the barrier layer.

Priority: US2005-0664164 Applic. Date: 2005-09-29; US2004-0614431P Applic. Date: 2004-09-29; WO2005-SG00323 Applic. Date: 2005-09-29

Inventor: CHONG EE JAY (SG); LIM CHWEE TECK (SG); RAMAKRISHNA SEERAM (SG); PHAN TOAN THANG (SG); LIM IVOR JIUN (SG)


Publication No.: US Appl: 20090209508 A1 Published: 2009-08-20

Title: Compounds for Photochemotherapy

Applicant: UNIV GENEVE (CH)

Application No.: US2006-0914446 Applic. Date: 2006-05-15

Abstract: Enzyme-activatable photosensitizing polymer conjugates are disclosed for photochemotherapeutic treatment of human diseases and disorders, bacteriologic or virologic indications, cosmetic applications and other pathologic situations. These polymer conjugates may comprise a polymer carrier, a photosensitizer, a quencher, a targeting molecule and/or a biocompatibilizing unit. These macromolecular conjugates may be designed to guide to the target tissue a photosensitizing agent in an inactive, non-phototoxic form. However, upon entering the target environment, in which certain enzymes are presently active, the conjugate may release its photosensitizers in its fully active form, resulting in a highly localized activation of the photoactive agent. Also described here are methods, compositions and kits for the preparation and testing of such photochemotherapcutic conjugates.

Priority: US2005-0681244P Applic. Date: 2005-05-16; WO2006-IB03547 Applic. Date: 2006-05-15; US2006-0914446 Applic. Date: 2006-05-15

Inventor: LANGE NORBERT (CH); CAMPO MARINO A (CH)


Publication No.: US Appl: 20090214474 A1 Published: 2009-08-27

Title: Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development

Application No.: US2009-0387239 Applic. Date: 2009-04-30

Abstract: The present invention relates to prevention of congenital deformations. The invention further relates to cancer inhibition and prevention. The invention further relates to methods and compositions to modulate, antagonize, or agonize disparate signaling pathways that may converge to regulate patterning events and gene expression during prenatal development, post-natal development, and during development in the adult organism.

Priority: US2009-0387239 Applic. Date: 2009-04-30; US2006-0591398 Applic. Date: 2006-11-01; US2007-0001869 Applic. Date: 2007-12-13

Inventor: JENNINGS BARBARA BROOKE (US)


Publication No.: US Appl: 20090232857 A1 Published: 2009-09-17

Title: METHOD AND PROCESS FOR THE PRODUCTION OF MULTI-COATED RECOGNITIVE AND RELEASING SYSTEMS

Applicant: UNIV TEXAS (US)

Application No.: US2008-0328469 Applic. Date: 2008-12-04

Abstract: The present invention includes compositions, methods, systems for the controlled delivery of an active agent within a polymeric network upon the binding of a molecule that decreases the structural integrity of the polymeric network at one or more micro- or nanovacuoles.

Priority: US2008-0328469 Applic. Date: 2008-12-04; US2008-0047309 Applic. Date: 2008-03-12

Inventor: PEPPAS NICHOLAS A (US)


Publication No.: US Appl: 20090252810 A1 Published: 2009-10-08

Title: Aryl/alkyl Succinic Anhydride-Hyaluronan Derivatives

Applicant: NOVOZYMES BIOPOLYMER AS (DK)

Application No.: US2006-0572954 Applic. Date: 2006-09-26

Abstract: The present invention relates to the modification of hyaluronic acid (HA) with aryl/alkyl succinic anhydrides (ASA) to produce aryl/alkyl succinic anhydride HA derivatives, to the derivatives as such, and to their applications and uses, particularly in the cosmetic and biomedical industries. The ASA-HA derivatives are expected to have interesting properties that can be used for advanced formulation (bind stronger to the skin compared to non-modified HA), possibly also in delivery systems for actives or drugs by encapsulation (nano/micro capsules) or formation of nano/micro spheres. Further, the low MW ASA-HA derivatives are expected to penetrate the skin more efficiently than non-modified HA of the same MW.

Priority: US2006-0572954 Applic. Date: 2006-09-26; DK2005-0001332 Applic. Date: 2005-09-26; US2005-0721232P Applic. Date: 2005-09-27; WO2006-DK00523 Applic. Date: 2006-09-26

Inventor: TOMMERAAS KRISTOFFER (SE); EENSCHOOTEN CORINNE (FR)


Publication No.: US Appl: 20090254014 A1 Published: 2009-10-08

Title: MASK FOR MASSAGING THE FACE

Application No.: US2009-0414453 Applic. Date: 2009-03-30

Abstract: A mask for massaging the face which is able to come close to and massage the face using pneumatic pressure created by the injection of air into the mask. The mask includes a massaging section for massaging the wearer's face using pneumatic pressure, so that the wearer's face is massaged using pneumatic pressure without exerting a negative influence on a human body, nor causing skin trouble and whereby the mask is easy to carry so that the mask is used irrespective of place and time of use.

Priority: KR2008-0031482 Applic. Date: 2008-04-04

Inventor: SON GI-JUN (KR)


Publication No.: US Appl: 20090260651 A1 Published: 2009-10-22

Title: Hair styling apparatus with retractable styling heads

Applicant: DICKSON IND CO LTD (CN)

Application No.: US2006-0991308 Applic. Date: 2006-08-30

Abstract: A hair styling apparatus includes a handle, a styling head and a heater. The handle has a pair of pivotally joined arms, and the head includes a pair of styling members which cooperate to form styling surfaces of the styling head. Each styling member is extendable from and retractable into the handle.

Priority: CN2005-1007583 Applic. Date: 2005-08-30; WO2006-IB02374 Applic. Date: 2006-08-30

Inventor: CHAN WING KIN (CN)


Publication No.: US Appl: 20090269395 A1 Published: 2009-10-29

Title: USE OF PROTOBERBERINES AS AN ACTIVE SUBSTANCE REGULATING THE PILOSEBACEOUS UNIT

Applicant: SEDERMA (FR)

Application No.: US2006-0991587 Applic. Date: 2006-09-06

Abstract: The present invention relates to cosmetic use, by topic application on the skin of at least one protoberberine, with exception of berberine, or a vegetable extract containing it, as an active substance reducing activity of the pilosebaceous unit, preferably inhibiting activity of the pilosebaceous unit. In particular, the invention relates to cosmetic use of at least one protoberberine, with exception of berberine, or a vegetable extract containing it, as an agent reducing, preferably inhibiting the growth of hairs of the face and/or the body, and/or seborrheic activity of the sebaceous glands.; The invention also relates to a cosmetic composition comprising in a dermatologically acceptable carrier, at least one protoberberine, with exception of berberine, or a vegetable extract containing protoberberines, as an active substance, which reduces, preferably inhibits the skin's pilosebaceous unit activity.

Priority: FR2005-0009100 Applic. Date: 2005-09-06; WO2006-IB53136 Applic. Date: 2006-09-06

Inventor: LINTNER KARL (FR); MAS CHAMBERLIN CLAIRE (FR)


Publication No.: US Appl: 20090297468 A1 Published: 2009-12-03

Title: Mixtures Comprising Anthranilic Acid Amides and Cooling Agents as Cosmetic and Pharmaceutical Compositions for Alleviating Itching

Applicant: SYMRISE GMBH & CO KG (DE)

Application No.: US2006-0917370 Applic. Date: 2006-06-14

Abstract: The invention relates to a mixture comprising or consisting of: (a) one or more compounds of Formula 1: where the symbols in the compound or each compound of Formula 1 are defined as follows: m=0, 1, 2 or 3, p=0, 1 or 2, n=0, 1 or 2, where, when n=1 or 2, R1 and R2 in pairs are each H or together are another chemical bond, where, when m=1, 2 or 3, each X independently of the others is OH, Oalkyl or Oacyl, and where, when p=1 or 2, each Y independently of the others is OH, Oalkyl or Oacyl, and R3=H or alkyl, R3=H also representing the corresponding cosmetically or pharmaceutically acceptable salts and solvates; and (b) one or more cooling agents.

Priority: WO2006-EP62520 Applic. Date: 2006-05-23; WO2006-EP63175 Applic. Date: 2006-06-14; US2005-0690153P Applic. Date: 2005-06-14

Inventor: VIELHABER GABRIELE (DE); SCHMAUS GERHARD (DE); PILLAI RAVIKUMAR (US)


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