US PROVISIONAL PATENT APPLICATIONS IN EXCIPIENTS, DELIVERY AND RELEASE OF PHARMACEUTICAL COMPOSITIONS PUBLISHED IN 2013
This list includes Provisional Patent Applications published in the United States. The list was retrieved by searching the claims section of all patent applications. Salient search terms
included pharmaceutical formulations, excipients, strips, gums, cellulose, lozenge, tablets, capsules, suppositories; solid dosage, nasal inhalation; time, control or sustained drug release;
polysaccharides, polymeric excipients, hyaluronic acid, micro- and nano-spheres, carbomer, povidone, polyacrylates, polymerthacrylates; emulsions; enemas, vaginal, rectal, nasal, ocular
or buccal administration of medications, etc.
US Patent Applications in Excipients, Delivery and Release of
Pharmaceutical Compositions and Actives Published in 2013

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US PATENT APPLICATIONS IN PHARMACEUTICAL EXCIPIENTS AND FORMULATION PUBLISHED IN 2013



Application No.: US20130004488A1  Published: 03/Jan/2013

Title: ANTI-CANCER AGENT DELIVERY VEHICLES CAPABLE OF IMPROVED LOADING

Applicant/Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Application No.: 13/634036   Filing Date: 11/Mar/2011

Abstract:

There is provided a conjugate of a delivery agent containing a chemical moiety and at least one flavonoid. The flavonoid exists in a monomeric form or dimeric form before conjugation and remains in the monomeric form or dimeric form after conjugation. Preferably, the conjugate comprises two flavonoids. The delivery agent is conjugated at the C6 and/or the C8 position of the A ring of the flavonoid. An anti-cancer agent delivery vehicle comprising an anti-cancer agent and the conjugate is also provided.

Priority: WO2011SG00100 Applic. Date: 2011-03-11; US2010-312885P Applic. Date: 2010-03-11

Inventor: KURISAWA MOTOICHI [SG]; LIANG KUN [SG]; TAN SUSI [SG]; CHUNG JOO EUN [SG]; YING JACKIE Y [SG]


Application No.: US20130004578A1  Published: 03/Jan/2013

Title: Solid Pharmaceutical Dosage Formulation

Applicant/Assignee: ABBVIE INC

Application No.: 13/608482   Filing Date: 10/Sep/2012

Abstract:

The present invention provides a pharmaceutical dosage formulation, and more particularly, a pharmaceutical dosage formulation comprising an HIV protease inhibitor.

Priority: US2005-064467 Applic. Date: 2005-02-23

Inventor: ROSENBERG JOERG [DE]; REINHOLD ULRICH [DE]; LIEPOLD BERND [DE]; BERNDL GUNTHER [DE]; BREITENBACH JOERG [DE]; ALANI LAMAN [US]; GHOSH SOUMOJEET [US]


Application No.: US20130011342A1  Published: 10/Jan/2013

Title: SURFACTANT-FREE, WATER-FREE FORMABLE COMPOSITION AND BREAKABLE FOAMS AND THEIR USES

Applicant/Assignee: FOAMIX LTD

Application No.: 13/499709   Filing Date: 01/Oct/2010

Abstract:

A substantially surface active agent-free and foam adjuvant-free composition which includes a hydrophobic solvent, a wax and a propellant. A substantially surface active agent-free and foam adjuvant-free composition, further comprising, a tetracycline antibiotic, or one or More other active agents. A method of treatment, using a substantially surface active agent-free and substantially foam adjuvant-free composition.

Priority: US2010-385385P Applic. Date: 2010-09-22; US2010-322148P Applic. Date: 2010-04-08; US2009-248144P Applic. Date: 2009-10-02; US2010-331126P Applic. Date: 2010-05-04; US2010-349911P Applic. Date: 2010-05-31; US2010-380568P Applic. Date: 2010-09-07; WO2010IB02613 Applic. Date: 2010-10-01; US2010-388884P Applic. Date: 2010-10-01

Inventor: TAMARKIN DOV [IL]; GAZAL ELANA [IL]; PAPIASHVILI IRAKLIY [IL]; HAZOT YOHAN [IL]; SCHUZ DAVID [IL]; KEYNAN RITA [IL]; PAPIASHVILE NUKZI [IL]


Application No.: US20130011353A1  Published: 10/Jan/2013

Title: 2-HYDROXY-6-METHYL-HEPTANE DERIVATIVES AS PERFUMING INGREDIENTS

Applicant/Assignee: FIRMENICH SA

Application No.: 13/635571   Filing Date: 19/Apr/2011

Abstract:

The invention relates to a method of use of certain derivatives of formula (I) in the form of any one of its stereoisomers or a mixture thereof, and wherein R1 represents a hydrogen atom, a C1-4 alkyl or alkenyl group, or a (CHR)2OH group, each R being a hydrogen atom or a methyl group

R2 represents a hydrogen atom or a methyl, ethyl or n-propyl group

and R3 represents a hydrogen atom or a methyl group, as perfuming ingredients. The present invention concerns also certain compounds and compositions or articles containing such compounds.

Priority: EP20100161549 Applic. Date: 2010-04-30; US2010-329723P Applic. Date: 2010-04-30; WO2011IB51690 Applic. Date: 2011-04-19

Inventor: RAUTENSTRAUCH VALENTIN [FR]; FANTINI PIERO [CH]


Application No.: US20130011459A1  Published: 10/Jan/2013

Title: Composite for Controleed Release of Small Molecules in Aquatic Environments

Applicant/Assignee: NAVAL RESEARCH LABORATORY

Application No.: 13/612442   Filing Date: 12/Sep/2012

Abstract:

A composite material formulated for slow release of a small molecule in seawater includes a porous inorganic oxide framework and micelles embedded within the pores of the framework. The micelles include a surfactant and a small molecule, the surfactant being present in the composite material at no more than 80 parts by weight per 100 parts by weight inorganic oxide, the composite material being stable in seawater for releasing the small molecule over at least 20 days.

Priority: US2010-813916 Applic. Date: 2010-06-11

Inventor: MELDE BRIAN [US]; MARKOWITZ MICHAEL A [US]


Application No.: US20130011464A2  Published: 10/Jan/2013

Title: DRUG CARRIER AND DRUG CARRIER KIT FOR INHIBITING FIBROSIS

Applicant/Assignee: NITTO DENKO CORPORATION

Application No.: 13/439330   Filing Date: 04/Apr/2012

Abstract:

An astrocyte-specific drug carrier containing a retinoid derivative and/or a vitamin A analog as a constituent

a drug delivery method with the use of the same

a drug containing the same

and a therapeutic method with the use of the drug. By binding a drug carrier to a retinoid derivative such as vitamin A or a vitamin A analog or encapsulating the same in the drug carrier, a drug for therapeutic use can be delivered specifically to astrocytes. As a result, an astrocyte-related disease can be efficiently and effectively inhibited or prevented while minimizing side effects. As the drug inhibiting the activity or growth of astrocytes, for example, a siRNA against HSP47 which is a collagen-specific molecule chaperone may be encapsulated in the drug carrier.

Thus, the secretion of type I to type IV collagens can be inhibited at the same time and, in its turn, fibrosis can be effectively inhibited.

Priority: JP20040382791 Applic. Date: 2004-12-22; US2008-793736 Applic. Date: 2008-04-08; WO2005JP23619 Applic. Date: 2005-12-22

Inventor: NIITSU YOSHIRO [JP]; KATO JUNJI [JP]; SATO YASUSHI [JP]


Application No.: US20130012387A1  Published: 10/Jan/2013

Title: Biocide Compositions Comprising Glycerol(Ether)Phosphates

Applicant/Assignee: COGNIS IP MANAGEMENT GMBH

Application No.: 13/636204   Filing Date: 06/Mar/2011

Abstract:

Suggested are biocide compositions, comprising (a) Glycerol(ether)phosphates

(b) Biocides and optionally (c) Oil components or co-solvents and/or (d) Emulsifiers. The compositions show excellent adjuvant and complexing properties.

Priority: EP20100003102 Applic. Date: 2010-03-24; WO2011EP01279 Applic. Date: 2011-03-16

Inventor: BIGORRA LLOSAS JOAQUIN [ES]; KARLIK DANIEL J [US]; ANDERSON TIMOTHY H [US]


Application No.: US20130017263A1  Published: 17/Jan/2013

Title: GASTRIC ACID SECRETION INHIBITING COMPOSITION

Applicant/Assignee: OREXO AB

Application No.: 13/621423   Filing Date: 17/Sep/2012

Abstract:

An oral pharmaceutical dosage form comprises pharmacologically effective amounts of an acid-susceptible proton pump inhibitor and an H2 receptor antagonist in combination with at least on pharmacologically acceptable excipient which causes a delayed release and/or an extended release of the proton pump inhibitor. The H2 receptor antagonist is included in the dosage form in such a way that it is rapidly released after administration. This dosage form is suitable for the treatment of conditions associated with an excessive secretion of gastric acid and provides a suitable combination of a rapid onset and a long-lasting duration of the effect. The invention also relates to a method for manufacturing such a dosage form and to a method for the treatment of conditions associated with the secretion of gastric acid.

Priority: SE20020003065 Applic. Date: 2002-10-16; US201213355935 Applic. Date: 2012-01-23; US2010-660056 Applic. Date: 2010-02-19; US2006-544750 Applic. Date: 2006-10-10; US2005-531598 Applic. Date: 2005-11-25; WO2003SE01598 Applic. Date: 2003-10-15

Inventor: PETTERSSON ANDERS [SE]; NYSTROM CHRISTER [SE]; HAKANSSON YVONNE [SE]


Application No.: US20130022560A1  Published: 24/Jan/2013

Title: NOVEL COMPOUNDS

Applicant/Assignee:

Application No.: 13/510134   Filing Date: 08/Dec/2010

Abstract:

The invention relates to novel polyglycerol based UV-filters as well as to topical compositions comprising such novel polyglycerol based UV-filters. Furthermore, the invention relates to the use of such novel polyglycerol based UV-filters to enhance the solubility of butyl methoxydibenzoylmethane or bis-ethylhexyloxyphenol methoxyphenyl triazine in cosmetic oils.

Priority: EP20090178495 Applic. Date: 2009-12-09; WO2010EP69135 Applic. Date: 2010-12-08

Inventor: SCHLIFKEPOSCHALKO ALEXANDER [CH]


Application No.: US20130022661A1  Published: 24/Jan/2013

Title: BIO-REMODABLE BONE AUGMENTATION DEVICE AND METHOD

Applicant/Assignee: WARSAW ORTHOPEDIC, INC

Application No.: 13/188135   Filing Date: 21/Jul/2011

Abstract:

A bio-remodable augmentation device including an implantable member configured for maintaining space in a bone defect. The implantable member is formed from a bio-remodable composite having structural properties so as to aid in the generation of new bone tissue and eventually be reabsorbed in the newly formed bone tissue. This structural and bio-remodable implant reduces, if not eliminates, the need to remove the implantable member from the patient once new bone tissue is formed. A kit including the implantable devices and bone growth material is disclosed. Methods of use are also disclosed.

Priority:

Inventor: MCKAY WILLIAM F [US]


Application No.: US20130023591A1  Published: 24/Jan/2013

Title: Phenyl-Containing Organopolysiloxane Composition, Raw Cosmetic Material, and Glossy Cosmetic Material

Applicant/Assignee:

Application No.: 13/519253   Filing Date: 27/Dec/2010

Abstract:

To provide a phenyl-containing organopolysiloxane composition that has a high index of refraction of the entire composition and compounding stability in cosmetic formulation, excellent handling performance, and possibility of adjusting viscosity. Another objective is to provide a cosmetic raw material comprising the composition, and a cosmetic material. The invention is a phenyl-containing organopolysiloxane composition that has an index of refraction of the entire composition that is equal to or greater than 1.50 and that has a viscosity of the entire composition at 25 DEG C. in the range of 200 to 500,000 mPas.

Priority: JP20090297442 Applic. Date: 2009-12-28; WO2010JP73894 Applic. Date: 2010-12-27

Inventor: SHOJI HIROAKI [JP]; KANETA YASUHIRO [JP]; KANZAKI YASUE [JP]; KONDO HIDETOSHI [JP]


Application No.: US20130023592A1  Published: 24/Jan/2013

Title: PERFUME

Applicant/Assignee: COTY INC

Application No.: 13/529480   Filing Date: 21/Jun/2012

Abstract:

Inventive subject matter disclosed herein includes a perfume that includes water

alcohol

oil in a concentration of about 2 to 20% by weight

a scent imparting constituent

and a stabilizing agent in a concentration effective for imparting a capacity to make a misting spray pattern when the perfume is sprayed through a sprayer.

Priority: US201161509364P Applic. Date: 2011-07-19; US201161511288P Applic. Date: 2011-07-25

Inventor: BARONE SALVATORE J [US]; STAINA IRINA [US]; BLEUEZ LOIC [FR]


Application No.: US20130023736A1  Published: 24/Jan/2013

Title: SYSTEMS FOR DRUG DELIVERY AND MONITORING

Applicant/Assignee:

Application No.: 13/187658   Filing Date: 21/Jul/2011

Abstract:

Films that comprise an active agent for delivery to a tissue. The films may include carboxyls that form a chemical association with the active agent and/or hydrophilic domains or particles that comprise the active agent.

Priority:

Inventor: HARPSTEAD STANLEY DALE [US]; BARBER JR LOREN L [US]


Application No.: US20130028955A1  Published: 31/Jan/2013

Title: SUSTAINED RELEASE ORAL MATRIX AND METHODS OF MAKING THEREOF

Applicant/Assignee:

Application No.: 13/190398   Filing Date: 25/Jul/2011

Abstract:

A solid dosage form suitable for forming a tablet for the containment and delivery of medicament is provided wherein the matrix forming material is a pressure sensitive adhesive, present in the amount from about 0.1 to about 40 weight %, based on the total weight of the composition. The dosage form is comprised of the medicament and a water-insoluble polymer silicone pressure sensitive adhesive and allows release of the medicament in a controlled fashion depending on simple parameters such as weight percent of the polymer silicone adhesive. A sustained release dosage form is provided for delivery of medicament wherein the release rate of medicament does not depend on the dissolution medium of the pH. Another aspect of invention is formation of solid tablets of poorly compressible material and the method for making the solid composition. The dosage form for this invention s particularly suitable for oral dosage forms.

Priority:

Inventor: TOLIA GAURAV THAKERSI [US]


Application No.: US20130028967A1  Published: 31/Jan/2013

Title: THERAPEUTIC AGENT FOR PULMONARY FIBROSIS

Applicant/Assignee:

Application No.: 13/648543   Filing Date: 10/Oct/2012

Abstract:

Disclosed are: a substance transfer carrier to an extracellular matrix-producing cell in the lung, which comprises a retinoid

a therapeutic agent for pulmonary fibrosis, which utilized the carrier

and a preparation kit of the therapeutic agent.

Priority: JP20040382791 Applic. Date: 2004-12-22; JP20080068227 Applic. Date: 2008-03-17; US201213491976 Applic. Date: 2012-06-08; US2010-933075 Applic. Date: 2010-12-10; WO2009JP01148 Applic. Date: 2009-03-16; US201213439330 Applic. Date: 2012-04-04; US2008-793736 Applic. Date: 2008-04-08; WO2005JP23619 Applic. Date: 2005-12-22

Inventor: NITTO DENKO CORPORATION [JP]


Application No.: US20130028975A1  Published: 31/Jan/2013

Title: HEMOSTATIC SPONGE

Applicant/Assignee: BAXTER HEALTHCARE, S.A, BAXTER INTERNATIONAL, INC

Application No.: 13/639490   Filing Date: 07/Apr/2011

Abstract:

The present invention provides a hemostatic porous composite sponge comprising i) a matrix of a biomaterial and ii) one hydrophilic polymeric component comprising reactive groups wherein i) and ii) are associated with each other so that the reactivity of the polymeric component is retained, wherein associated means that-said polymeric component is coated onto a surface of said matrix of a biomaterial, or-said matrix is impregnated with said polymeric material, or-both.

Priority: US2010-321661P Applic. Date: 2010-04-07; WO2011EP55418 Applic. Date: 2011-04-07; US2010-424031P Applic. Date: 2010-12-16

Inventor: HEDRICH HANS CHRISTIAN [AT]; HOEFINGHOFF JORIS [AT]


Application No.: US20130035399A1  Published: 07/Feb/2013

Title: MARKED INORGANIC ADDITIVES

Applicant/Assignee:

Application No.: 13/624025   Filing Date: 21/Sep/2012

Abstract:

The subject matter of the present invention is marked inorganic additives, a method for their production and also their use.

Priority: DE20051033208 Applic. Date: 2005-07-13; US2006-988596 Applic. Date: 2006-07-06; WO2006EP63942 Applic. Date: 2006-07-06

Inventor: SACHTLEBEN CHEMIE GMBH [DE]


Application No.: US20130039964A1  Published: 14/Feb/2013

Title: METAL ENTRAPPED BIOACTIVE COMPOSITES

Applicant/Assignee: HADASSAH ACADEMIC COLLEGE, YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREWUNIVERSITY OF JERUSALEM, LTD

Application No.: 13/643247   Filing Date: 26/Apr/2011

Abstract:

The present invention provides composites comprising at least one bioactive agent entrapped within a matrix of at least one metal

wherein said composite controllably releases at least one of said bioactive agent and metal or ion thereof, processes for the preparation of composites of the invention, compositions and products comprising composites of the invention and various uses thereof.

Priority: US2010-327957P Applic. Date: 2010-04-26; WO2011IL00329 Applic. Date: 2011-04-26

Inventor: AVNIR DAVID [IL]; BEN-KNAZ RACHEL [IL]; PEDAHZUR RAMI [IL]


Application No.: US20130039981A1  Published: 14/Feb/2013

Title: Quick Dissolving, Long Acting Zinc Therapeutic Formulations

Applicant/Assignee:

Application No.: 13/557432   Filing Date: 25/Oct/2012

Abstract:

The present invention comprises a quick dissolving, long acting zinc therapeutic cold formulation containing high levels of an active compound encapsulated within bioadhesive/muco-adhesive polymers as a controlled release oral drug delivery system. The composition allows for increased residence time for enhanced prophylactic and therapeutic efficacy within the mouth and oral cavity. This allows for a reduction in the number of doses necessary to achieve therapeutic relief which will result in increased patience compliance.

Priority: US201161512545P Applic. Date: 2011-07-28

Inventor: CHERURKURI SUBRAMAN RAO [US]


Application No.: US20130039985A1  Published: 14/Feb/2013

Title: Method for aligning cells and applying homogenous strain throughout deformable engineered tissue constructs

Applicant/Assignee:

Application No.: 13/568057   Filing Date: 06/Aug/2012

Abstract:

A process creates a homogenous sheet of engineered tissue comprised of encapsulated cells and a deformable engineered tissue construct. In the embodiment consisting of a collagen construct with encapsulated cells capable of contracting the matrix, the collagen fibers and encapsulated cells are aligned during the process. An apparatus can deliver controlled homogenous strain and stress to a thin sheet of engineered tissue. This process allows application of dynamic, uniform tensile loading to deformable engineered tissue constructs and creation of an engineered cell-delivery construct with alignment of both fibers and encapsulated cells.

Priority: US201161521409P Applic. Date: 2011-08-09

Inventor: HARRIS MATTHEW THOMAS [US]


Application No.: US20130045162A1  Published: 21/Feb/2013

Title: DELIVERY SYSTEM FOR SPECIFICALLY TARGETING CANCER CELLS AND METHOD OF USE THEREOF

Applicant/Assignee: MOREHOUSE SCHOOL OF MEDICINE

Application No.: 13/569941   Filing Date: 08/Aug/2012

Abstract:

Methods for prevention, treatment or inhibition of the growth or metastasis of cancer cells in a subject are disclosed. One method comprises the step of administering to the subject a therapeutically effective amount of tumor associated antigen binding ligand-coated planetary ball milled (PBM) nanoparticles containing a cytotoxic agent.

Priority: US201161523626P Applic. Date: 2011-08-15

Inventor: LILLARD JR JAMES W [US]; SINGH SHAILESH [US]; SINGH RAJESH [US]


Application No.: US20130045272A1  Published: 21/Feb/2013

Title: AGENT FOR TREATING MYELOFIBROSIS

Applicant/Assignee: NITTO DENKO CORPORATION

Application No.: 13/648578   Filing Date: 10/Oct/2012

Abstract:

Disclosed is a substance delivery carrier for an extracellular-matrix-producing cell in the bone marrow, which comprises a retinoid. Also disclosed in an agent for treating myelofibrosis by utilizing a substance capable of regulating the activity or proliferation of an extracellular-matrix-producing cell in the bone marrow.

Priority: JP20080228338 Applic. Date: 2008-09-05; US201113062214 Applic. Date: 2011-05-17; WO2009JP04369 Applic. Date: 2009-09-04

Inventor: NIITSU YOSHIRO [JP]; MATSUNAGA TAKUYA [JP]


Application No.: US20130045277A1  Published: 21/Feb/2013

Title: BIOCOMPATIBLE DEVICE

Applicant/Assignee:

Application No.: 13/576718   Filing Date: 01/Feb/2011

Abstract:

Disclosed is a biocompatible device surface-coated on the base material thereof with a biocompatible polymer layer having antithrombogenicity and endothelialization activity, and embedded in or attached to a living body for use. The polymer layer comprises a polymer matrix formed by the crosslinking of a cell-adhesive peptide-containing polymer.

Priority: JP20100022565 Applic. Date: 2010-02-03; WO2011JP52058 Applic. Date: 2011-02-01

Inventor: TAGUCHI TETSUSHI [JP]; KATADA YASUYUKI [JP]; NAGAI RYOZO [JP]; MANABE ICHIRO [JP]; FUJIU KATSUHITO [JP]


Application No.: US20130046028A1  Published: 21/Feb/2013

Title: Cosmetic Raw Material

Applicant/Assignee: DOW CORNING TORAY CO., LTD, DOW CORNING CORPORATION

Application No.: 13/643571   Filing Date: 28/Apr/2011

Abstract:

A cosmetic raw material comprising the following components (A), (B), and (C): (A) a specific polyether-modified organopolysiloxane

(B) a chain-form silicone oil that is a liquid at 25 DEG C., does not contain a cyclic structure, and does not contain a resinous structure

and (C) an oil that is a liquid at 30 DEG C. and that characteristically (c1) has at least one hydroxyl group in each molecule, (c2) has from 0 to 3, as the number of moles of addition, oxyethylene units in each molecule, (c3) has an HLB value in the range from 0.1 to 6.0, and (c4) has an average molecular weight in the range from 200 to 7000.

Priority: US2010-329128P Applic. Date: 2010-04-29; WO2011US34263 Applic. Date: 2011-04-28

Inventor: DEETH BRIAN P [US]; FURUKAWA HARUHIKO [JP]; SOUDA TATSUO [JP]; TAMURA SEIKI [JP]


Application No.: US20130052142A1  Published: 28/Feb/2013

Title: LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OF PREPARING AND USING THE SAME

Applicant/Assignee: CELONOVA BIOSCIENCES GERMANY GMBH

Application No.: 13/623151   Filing Date: 20/Sep/2012

Abstract:

Particles are provided for use in therapeutic and/or diagnostic procedures. The particles include poly[bis(trifluoroethoxy)phosphazene] and/or a derivatives thereof which may be present throughout the particles or within an outer coating of the particles. The particles can also include a core having a hydrogel formed from an acrylic-based polymer. Barium sulfate may also be provided to the core of the particles as a coating or absorbed within the core of the particles. The particles can be used to minimize blood flow to mammalian tissues by occluding at least a portion of a blood vessel of the mammal, or to deliver an active agent to a localized area within a body of a mammal by contacting a localized area with at least one of the particles. Further, the particles are useful in sustained release formulations including active agent(s) for oral administration, as tracer particles for injection into the bloodstream of a mammal or for use in enhanced ultrasound imaging. The particles may include agents for increasing density for achieving useful buoyancy levels in suspension.

Priority: US2005-684307P Applic. Date: 2005-05-24; US2004-621729P Applic. Date: 2004-10-25; US2005-257535 Applic. Date: 2005-10-25

Inventor: HARDER PHILIPP [DE]; FRITZ OLAF [DE]; FRITZ ULF [DE]


Application No.: US20130052151A1  Published: 28/Feb/2013

Title: 3-METHYL-6-CYCLOHEXADECEN-1-ONE AND ITS USE IN PERFUME COMPOSITIONS

Applicant/Assignee: INTERNATIONAL FLAVORS & FRAGRANCES INC

Application No.: 13/214315   Filing Date: 22/Aug/2011

Abstract:

The present invention is directed to a novel compound, 3-methyl-cyclohexadec-6-enone, and a method of improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of 3-methyl-cyclohexadec-6-enone.

Priority:

Inventor: NARULA ANUBHAV P S [US]; ARRUDA EDWARD MARK [US]; AMORELLI BENJAMIN [US]; SCHIET FRANC T [NL]


Application No.: US20130052237A1  Published: 28/Feb/2013

Title: Methods of Manufacturing Viscous Liquid Pharmaceutical Formulations

Applicant/Assignee: INTARCIA THERAPEUTICS, INC

Application No.: 13/598405   Filing Date: 29/Aug/2012

Abstract:

A liquid composition in an osmotic drug delivery system and a dosage form in an osmotic drug delivery system is disclosed comprising an amphiphilic molecule, a non-aqueous liquid solvent, and a pharmaceutically active agent.

Priority: US201113090947 Applic. Date: 2011-04-20; US2009-655397 Applic. Date: 2009-12-29; US2004-988716 Applic. Date: 2004-11-15; US2003-520605P Applic. Date: 2003-11-17

Inventor: ELIAZ ROM EZER [US]; ZHANG YUANPENG [US]; ROHLOFF CATHERINE MANYA [US]; WEEKS ERIC WILLIAM [US]; JUNNARKAR GUNJAN [US]


Application No.: US20130052354A1  Published: 28/Feb/2013

Title: EVAPORATION OPERATIVE MATERIALS HAVING LOW ENVIRONMENTAL IMPACT

Applicant/Assignee: HONEYWELL INTERNATIONAL INC

Application No.: 13/593391   Filing Date: 23/Aug/2012

Abstract:

A composition comprising: (a) at least one active component

and (b) a carrier in an amount effective to at least partially solvate or at least partially emulsify said active component, said carrier comprising monochloro,trifluoropropene.

Priority: US201161526859P Applic. Date: 2011-08-24

Inventor: HULSE RYAN [US]; MERCIER DIANA [US]; COOK KANE [US]; BASU RAJAT S [US]; PAONESSA MARTIN R [US]


Application No.: US20130053452A1  Published: 28/Feb/2013

Title: COMPOSITION MADE OF POLYALKOXYLATED DERIVATIVES OF TRIMETHYLOLPROPANE AND FATTY ALCOHOLS, METHOD FOR PREPARING SAID COMPOSITION, AND USE THEREOF AS A REVERSER IN SELF-REVERSIBLE REVERSE LATEXES

Applicant/Assignee: SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC

Application No.: 13/696311   Filing Date: 11/Apr/2011

Abstract:

A novel composition made of polyalkoxylated derivatives of trimethylolpropane and fatty alcohols, the composition lending itself to the preparation thereof and to the use thereof as a reversing agent for a reversible reverse latex.

Priority: FR20100053532 Applic. Date: 2010-05-06; WO2011FR50817 Applic. Date: 2011-04-11

Inventor: MALLO PAUL [FR]; ROLLAND HERVE [FR]; DA COSTA GEORGES [FR]; BRAUN OLIVIER [FR]


Application No.: US20130058882A1  Published: 07/Mar/2013

Title: Personal Care Composition Comprising Butylated Hydroxyanisole Compound

Applicant/Assignee:

Application No.: 13/598866   Filing Date: 30/Aug/2012

Abstract:

A personal care composition which has an ethylenic monomer having a molecular weight of 500 g/mole or less and a compound selected from the group consisting of 2-tert-butyl-4-hydroxy-anisole, 3-tert-butyl-4-hydroxy-anisole, and mixtures thereof. The compound is present in the personal care composition in an amount of from about 1 milligram to about 1000 milligram per kilogram of the ethylenic monomer.

Priority: EP20120177613 Applic. Date: 2012-07-24; US201161530589P Applic. Date: 2011-09-02

Inventor: FLOHR ANDREAS [DE]; KRIPP THOMAS [DE]; MOTLEY CURTIS BOBBY [US]


Application No.: US20130059006A1  Published: 07/Mar/2013

Title: 3-DIMENSIONAL CARDIAC FIBROBLAST DERIVED EXTRACELLULAR MATRIX

Applicant/Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION

Application No.: 13/593969   Filing Date: 24/Aug/2012

Abstract:

A bioscaffold made from an isolated cardiac fibroblast-derived 3-dimensional extracellular matrix (ECM) is disclosed. The bioscaffold can be used as an epicardial patch for the delivery of therapeutic cells into myocardial tissue. Methods of making the 3-dimensional extracellular matrix using cultured cardiac fibroblasts are also disclosed.

Priority: US201161575658P Applic. Date: 2011-08-25

Inventor: SCHMUCK ERIC G [US]; SAUPE KURT W [US]


Application No.: US20130059007A1  Published: 07/Mar/2013

Title: Modified Release Formulations Containing Drug-Ion Exchange Resin Complexes

Applicant/Assignee: TRIS PHARMA, INC, TRIS PHARMA. INC, NULL, NULL

Application No.: 13/666424   Filing Date: 01/Nov/2012

Abstract:

A coated drug-ion exchange resin complex comprising a core composed of a drug complexed with a pharmaceutically acceptable ion-exchange resin is provided. The drug-ion exchange resin complex is in admixture with a release retardant. The coating is a polyvinyl acetate polymer and a plasticizer. Methods of making and products containing this coated complex are described.

Priority: US2010-722857 Applic. Date: 2010-03-12; US2007-724966 Applic. Date: 2007-03-15; US2006-783181P Applic. Date: 2006-03-16

Inventor: MEHTA KETAN [US]; TU YU-HSING [US]


Application No.: US20130059924A1  Published: 07/Mar/2013

Title: PHOTOSTABILISERS

Applicant/Assignee: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG

Application No.: 13/697416   Filing Date: 13/Apr/2011

Abstract:

The present invention relates to the use of specific aldehydes or ketones of the formula I as photostabiliser for at least one compound to be stabilised. The invention furthermore relates to a method for the photostabilisation of a second compound by a compound of the formula I and to compositions comprising at least one compound of the formula I of this type.

Priority: EP20100005019 Applic. Date: 2010-05-12; WO2011EP01871 Applic. Date: 2011-04-13

Inventor: SCHEURICH RENE PETER [DE]; RUDOLPH THOMAS [DE]; PAN JUNYOU [DE]


Application No.: US20130064868A1  Published: 14/Mar/2013

Title: COMPOSITION FOR ENHANCING TRANSDERMAL ABSORPTION OF A DRUG AND PATCH PREPARATION

Applicant/Assignee:

Application No.: 13/611154   Filing Date: 12/Sep/2012

Abstract:

The problem of the present invention is to provide a composition for enhancing transdermal absorption of a drug, which shows a sufficiently high enhancing effect on transdermal absorption of a drug, particularly, a composition for enhancing transdermal absorption of a drug, which shows a sufficiently high enhancing effect on transdermal absorption of an acidic drug. A composition for enhancing transdermal absorption of a drug, comprising an unsaturated higher alcohol having 12-20 carbon atoms and a polyvalent alcohol having 3-8 carbon atoms. A composition for enhancing transdermal absorption of a drug, comprising an unsaturated higher alcohol having 12-20 carbon atoms, a polyvalent alcohol having 3-8 carbon atoms and an organic amine having 2-9 carbon atoms.

Priority: JP20110200023 Applic. Date: 2011-09-13

Inventor: OKAZAKI ARIMICHI [JP]; MUKOBATA TSUYOSHI [JP]; SAKAMOTO SACHIKO [JP]; HANATANI AKINORI [JP]


Application No.: US20130064869A1  Published: 14/Mar/2013

Title: COMPOSITION FOR ENHANCING TRANSDERMAL ABSORPTION OF A DRUG AND PATCH PREPARATION

Applicant/Assignee:

Application No.: 13/611179   Filing Date: 12/Sep/2012

Abstract:

The problem of the present invention is to provide a composition which shows a sufficiently high enhancing effect on transdermal absorption of a drug, particularly, a composition which shows a sufficiently high enhancing effect on transdermal absorption of a drug in a patch preparation. A composition for enhancing transdermal absorption of a drug of a patch preparation, containing a higher alcohol having 14-20 carbon atoms and a polyvalent alcohol having 3-8 carbon atoms.

Priority: JP20110200020 Applic. Date: 2011-09-13

Inventor: OKAZAKI ARIMICHI [JP]; MUKOBATA TSUYOSHI [JP]; SAKAMOTO SACHIKO [JP]; HANATANI AKINORI [JP]


Application No.: US20130065844A1  Published: 14/Mar/2013

Title: Compositions of Stable Tiacumicins

Applicant/Assignee:

Application No.: 13/416768   Filing Date: 09/Mar/2012

Abstract:

The present invention is related to pharmaceutical compositions of one or more tiacumicins that exhibit improved stability, and methods of treatment using such formulations. The formulations contain one or more tiacumicins, such as difimicin, and one or more antioxidants, such as butylated hydroxytoluene, and, optionally, one or more pharmaceutically acceptable excipients.

Priority: US2008-008751 Applic. Date: 2008-01-14; US2007-881137P Applic. Date: 2007-01-19

Inventor: SANGHVI SUKETU [US]; ROACH MARK [US]; ZHOU JOSEPH F [US]; MITTLEBERG ERIC MICHAEL [US]; HE PING [US]


Application No.: US20130065885A1  Published: 14/Mar/2013

Title: ORAL THERAPEUTIC COMPOUND DELIVERY SYSTEM

Applicant/Assignee: IMAGINOT PTY LTD

Application No.: 13/618728   Filing Date: 14/Sep/2012

Abstract:

The present invention relates generally to therapeutic formulations. More particularly, this present invention provides an oral delivery system for a therapeutic compound that is a base, a salt of a base or an amphoteric compound or a salt of a amphoteric compound with pharmacological, physiological or biochemical activity or a proactive form thereof. The present invention even more particularly provides a swallow formulation comprising a therapeutic compound that is a base, a salt of a base, an amphoteric compound or a salt of an amphoteric compound which facilitates the rapid delivery of the therapeutic compound to the circulatory system.

Priority: US2008-597341 Applic. Date: 2008-06-11; WO2005AU00759 Applic. Date: 2005-05-27; US2004-575461P Applic. Date: 2004-05-28

Inventor: ROBERTS MICHAEL STEPHEN [AU]; JIANG RUOYING [AU]; BEZANEHTAK KEIVAN [AU]; DAVEY GREG ANDREW [AU]; DAVIDSON GEORGE ALEXANDER [AU]; ELLIOTT GERALDINE ANN [AU]; CHANDLER STEPHEN DOUGLAS [AU]; SARKAR MANTU [AU]


Application No.: US20130071476A1  Published: 21/Mar/2013

Title: Rapid Melt Controlled Release Taste-Masked Compositions

Applicant/Assignee:

Application No.: 13/589101   Filing Date: 31/Aug/2012

Abstract:

Rapid melt tablets that dissolve and release an active component in the oral cavity are comprised of a pharmaceutical active ingredient such as dextromethorphan complexed with a resin that is effective in taste-masking the otherwise bitter taste of the active making it convenient for oral administration. The drug/resin-complexed particles can be coated with water swellable or water insoluble polymers to impart controlled release properties to the active ingredient. A rapid melt tablet also comprises diluents, sweeteners, flavors, disintegrants and other excipients to form granules that can be compressed into tablets at low pressure without the need for a binding agent.

Priority: US201161525270P Applic. Date: 2011-08-19

Inventor: CHERUKURI SUBRAMAN RAO [US]


Application No.: US20130072575A1  Published: 21/Mar/2013

Title: Method and Composition for Treating Pain

Applicant/Assignee: JOHNSON & JOHNSON CONSUMER COMPANIES, INC

Application No.: 13/235947   Filing Date: 19/Sep/2011

Abstract:

Presented are methods of using topical analgesic compositions for rapid relief of muscular aches and pain where the analgesic composition has been stored at a temperature of less than 10 DEG Centigrade prior to use.

Priority:

Inventor: CHIN JENNIFER K [US]; RICK DONALD [US]; WALLACE ROSEMARIE [US]


Application No.: US20130072884A1  Published: 21/Mar/2013

Title: TRANSDERMAL COMPOSITIONS COMPRISING AN ACTIVE AGENT LAYER AND AN ACTIVE AGENT CONVERSION LAYER

Applicant/Assignee:

Application No.: 13/427602   Filing Date: 22/Mar/2012

Abstract:

Transdermal compositions are provided. Aspects of the transdermal compositions include: an active agent layer and a conversion layer, where the conversion layer includes a weak base and, optionally, a carboxylated component. Also provided are methods of using the transdermal compositions and kits containing the transdermal compositions.

Priority: US201161467337P Applic. Date: 2011-03-24

Inventor: HAMLIN RICHARD [US]; WEN JIANYE [US]


Application No.: US20130078282A1  Published: 28/Mar/2013

Title: FORMULATIONS DECREASING PARTICLE EXHALATION

Applicant/Assignee: PULMATRIX, INC

Application No.: 13/455585   Filing Date: 25/Apr/2012

Abstract:

Formulations have been developed for pulmonary delivery to treat or reduce the infectivity of diseases such as viral infections, especially tuberculosis, SARS, influenza and respiratory synticial virus in humans and hoof and mouth disease in animals, or to reduce the symptoms of allergy or other pulmonary disease. Formulations for pulmonary administration include a material that significantly alters physical properties such as surface tension and surface elasticity of lung mucus lining fluid, which may be isotonic saline and, optionally, a carrier. The formulation may be administered as a liquid solution, suspension, aerosol, or powder where the particles consist basically of an osmotically active solute. Drugs, especially antivirals or antibiotics, may optionally be included with the formulation. These may be administered with or incorporated into the formulation.

Priority: US2007-714999 Applic. Date: 2007-03-06; US2004-990996 Applic. Date: 2004-11-17; US2004-550601P Applic. Date: 2004-03-05; US2004-560470P Applic. Date: 2004-04-07; US2004-564189P Applic. Date: 2004-04-21; US2004-572631P Applic. Date: 2004-05-19; US2004-579425P Applic. Date: 2004-06-14

Inventor: EDWARDS DAVID A [US]; MAN JONATHAN C [US]; KATSTRA JEFFREY P [US]; CLARKE ROBERT W [US]


Application No.: US20130078299A1  Published: 28/Mar/2013

Title: Transdermal Patches Having Ionized Beam Crosslinked Polymers and Improved Release Characteristics

Applicant/Assignee: ALLIQUA, INC

Application No.: 13/444348   Filing Date: 11/Apr/2012

Abstract:

Crosslinked hydrogel-based transdermal pharmaceutical formulations. The hydrogel transdermal formulations. Transdermal patches are useful for administering a variety of drugs to patients. The transdermal patches here employ crosslinked-hydrogels generated through irradiation, thus eliminating any residual effects associated with chemical- or UV-based crosslinking procedures. The transdermal patches may be formed from a variety of high-molecular weight polymeric compounds and include substantial levels of water to improve skin tolerance by the patient. The transdermal patches may also include transcutol as a solvent for the drug, which has been found to increase the effectiveness of drug delivery. The present disclosure also provides for methods of loading a drug into a transdermal formulation after the crosslinking of the hydrogel, thus improving stability and bioavailability through avoiding exposure of the drug to the radiation used in the crosslinking procedure. The transdermal patches here are particularly effective in delivering lidocaine to patients in need thereof.

Priority: US201161473992P Applic. Date: 2011-04-11; US201161481449P Applic. Date: 2011-05-02

Inventor: HARRITON MATTHEW [US]; ROBB GREGORY [US]; HARLAND RONALD S [US]


Application No.: US20130079228A1  Published: 28/Mar/2013

Title: Agricultural spray solution compositions and methods

Applicant/Assignee:

Application No.: 13/200443   Filing Date: 23/Sep/2011

Abstract:

An agrichemical is disclosed having increased bio-activity which is adapted for spray application in a form which offers reduced aerial drift and improved deposition on organisms, reduced agglomeration and gellation problems, is adapted for use with chemicals, pesticides and fertilizers and allows for lower agrichemical use rates. Various adjuvants and surfactants are combined with fertilizers or pesticides, such as herbicides fungicides and insecticides, to reduce application problems relating to droplet size, foaming, chemical stability, plant and area coverage, droplet drift, surface tension, suspension, incompatability, phytoxicity, solubility, volatilization and evaporation, while providing enhanced bio-efficacy and low aquatic toxicity. Purifying the agrichemical composition water source by any of various known processes such as oxidation, ultra-filtration, deionization, reverse osmosis or nanofiltration lowers or removes alkaline components, such as calcium, magnesium, iron, sodium, etc., and reduces water hardness, and further increases the agrichemical's bio-efficacy.

Priority:

Inventor: FREED BRIAN E [US]


Application No.: US20130089585A1  Published: 11/Apr/2013

Title: FILLER COMPRISING BEADS

Applicant/Assignee: MERZ PHARMA GMBH & CO., KGAA

Application No.: 13/639013   Filing Date: 07/Apr/2011

Abstract:

The present invention pertains to a filler comprising beads wherein said beads comprise a polyanionic biopolymer and divalent cations and wherein said polyanionic biopolymer is not alginate. Further, the present invention pertains to a process for manufacturing the claimed filler, and to an injection device comprising the filler.

Priority: EP20100003794 Applic. Date: 2010-04-08; US2010-321964P Applic. Date: 2010-04-08; WO2011EP01737 Applic. Date: 2011-04-07

Inventor: KIEHM KEVIN [DE]; HAUPTMEIER BERNHARD [DE]; BODERKE PETER [DE]


Application No.: US20130090387A1  Published: 11/Apr/2013

Title: STABILIZED COMPOSITIONS COMPRISING A THERAPEUTICALLY ACTIVE AGENT AND AN OXIDIZING PRESERVATIVE

Applicant/Assignee: ALLERGAN, INC

Application No.: 13/690863   Filing Date: 30/Nov/2012

Abstract:

Citric acid and conjugate bases thereof are useful for stabilizing stabilized chlorine dioxide in the presence of therapeutically active agents and excipients in a composition. Ophthalmic compositions and methods related thereto are also disclosed herein.

Priority: US2005-570200 Applic. Date: 2005-05-19; US2004-865639 Applic. Date: 2004-06-09; WO2005US18026 Applic. Date: 2005-05-19

Inventor: LYONS ROBERT T [US]; JORDAN ROBERT S [US]


Application No.: US20130090390A1  Published: 11/Apr/2013

Title: FRAGRANCES WITH NOTE OF LILY OF THE VALLEY

Applicant/Assignee: SYMRISE AG

Application No.: 13/645871   Filing Date: 05/Oct/2012

Abstract:

A compound of formula (I) is described and use thereof as fragrance, especially as lily-of-the-valley fragrance and/or as an agent for increasing the substantivity and/or the retention of a fragrance preparation and/or as a fixative.

Priority: EP20110184441 Applic. Date: 2011-10-07; US201161544904P Applic. Date: 2011-10-07

Inventor: SINGER EMILIE [DE]; HOLSCHER BERND [DE]


Application No.: US20130095087A1  Published: 18/Apr/2013

Title: ABSORBABLE IN SITU GEL-FORMING SYSTEM, METHOD OF MAKING AND USE THEREOF

Applicant/Assignee: POLY-MED, INC

Application No.: 13/274824   Filing Date: 17/Oct/2011

Abstract:

An in situ gel-forming composition is disclosed. The in situ gel-forming composition comprises one or more absorbable polymers, solvents such as N-methyl-2-pyrrolidone, polyethylene glycol or DMSO, and optionally one or more bioactive agent. The composition forms a hydrogel or semi-solid mass on contact with an aqueous environment. The method of using in situ gel-forming composition for various applications is also disclosed.

Priority:

Inventor: SHALABY SHALABY W [US]; CORBETT JOEL [US]; OLBRICH JASON [US]


Application No.: US20130095147A1  Published: 18/Apr/2013

Title: SOL-GEL DERIVED BIOACTIVE GLASS POLYMER COMPOSITE

Applicant/Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC

Application No.: 13/690538   Filing Date: 30/Nov/2012

Abstract:

A bioactive sol-gel solution includes a biocompatible polymer, a gelable inorganic base material, and at least one calcium and phosphorous molecular species. The base material can be an alkoxide, such as TEOS. The polymer acts as a viscosity modifier to the sol or gel, increases the viscosity range over which fibers can be sprayed or spun, and broadens the time period over which fibers can be sprayed or spun. A bioactive glass composite can be formed from the bioactive sol-gel solution, including a fibrous form. Fibers can serve as a scaffolds for cell growth and in the repair of hard or soft tissue defects.

Priority: US2003-616884 Applic. Date: 2003-07-10; US2002-395186P Applic. Date: 2002-07-10

Inventor: HATCHER BRIAN M [US]; BRENNAN ANTHONY [US]; CUEVAS BRIAN [US]; SEEGERT CHARLES [US]


Application No.: US20130095153A1  Published: 18/Apr/2013

Title: STABLE METAL ION-LIPID POWDERED PHARMACEUTICAL COMPOSITIONS FOR DRUG DELIVERY

Applicant/Assignee: NOVARTIS AG

Application No.: 13/707563   Filing Date: 06/Dec/2012

Abstract:

A microparticle for drug delivery comprises an active agent and an excipient, the excipient comprising a metal ion-lipid complex. The metal ion is chosen from the group consisting of lanthanide metals, actinide metals, group IIa and IIIb metals, transition metals or mixtures thereof. The lipid comprises a phospholipid. The complex results in a glass transition temperature increase of the microparticle.

Priority: US2010-967482 Applic. Date: 2010-12-14; US2000-568818 Applic. Date: 2000-05-10

Inventor: DELLAMARY LUIS A [US]; REISS JEAN [FR]; SCHUTT ERNEST G [US]; WEERS JEFFRY G [US]; TARARA THOMAS E [US]


Application No.: US20130095183A1  Published: 18/Apr/2013

Title: BONE GRAFT SYSTEM

Applicant/Assignee:

Application No.: 13/806243   Filing Date: 22/Jun/2011

Abstract:

The bone graft system comprises a solid inorganic component, which is bone graft material, and a hydrogel. The hydrogel contains >2 ppm of silicon ions, calculated as parts by weight of Si per million of the aqueous component of the hydrogel. Preferably, the solid inorganic component comprises hydroxyapatite or a silicon-containing hydroxyapatite, and may be a silicon-containing hydroxyapatite having a Ca/P ratio in the range 2.05 to 2.55 and a Ca/(P+Si) molar ratio less than 1.66. Bone healing is promoted by delivery of silicon ion release from the hydrogel and by the solid inorganic component stimulating cell behavior.

Priority: GB20100010761 Applic. Date: 2010-06-25; WO2011GB00939 Applic. Date: 2011-06-22

Inventor: GIBSON IAIN RONALD [GB]; SKAKLE JANET MABEL SCOTT [GB]; CONWAY JORDAN CHRISTOPHER [GB]; ANNAZ BASIL [GB]


Application No.: US20130096205A1  Published: 18/Apr/2013

Title: AQUEOUS COMPOSITION TO BE CONTAINED IN CONTAINER

Applicant/Assignee: KAO CORPORATION

Application No.: 13/700322   Filing Date: 26/May/2011

Abstract:

Provided is an aqueous composition contained in a container, maintaining an excellent water-evaporation-inhibiting effect even when an alkali metal salt or the like is contained in the aqueous composition, and having excellent long-term stability. The aqueous composition contained in a container includes the following components (A) to (D): (A) a polyoxyethylene alkyl or alkenyl ether having an alkyl or alkenyl group having 20 to 24 carbon atoms and an average molar number of ethylene oxide added of 1.5 to 4, (B) a water-soluble polymer, (C) a nonionic surfactant having an ethylene oxide group (but excluding component (A)), and (D) water.

Priority: JP20100121631 Applic. Date: 2010-05-27; WO2011JP62062 Applic. Date: 2011-05-26

Inventor: MURATA TAKESHI [JP]


Application No.: US20130096206A1  Published: 18/Apr/2013

Title: POWDER TREATMENT AGENT COMPRISING SUGAR ALCOHOL-MODIFIED ORGANOPOLYSILOXANE

Applicant/Assignee: DOW CORNING TORAY CO., LTD

Application No.: 13/643780   Filing Date: 28/Apr/2011

Abstract:

The present invention has an objective to provide a surface treatment agent which is safe with no generation of hydrogen, can be suitably used in a surface treatment of powder(s), exhibits good compatibility with other raw materials of cosmetics, and therefore, can improve a dispersing property and stability of powder(s) contained in a cosmetic, as well as provide a powder which has been subjected to a surface treatment with the aforementioned powder treatment agent, and a cosmetic raw material and a cosmetic which are produced by blending them, exhibit superior storage stability, have a superior outer appearance, and exhibit a superior sensation during use. A sugar alcohol-modified organopolysiloxane having a specified structure is used in the powder treatment.

Priority: JP20100105888 Applic. Date: 2010-04-30; WO2011JP60800 Applic. Date: 2011-04-28

Inventor: IIMURA TOMOHIRO [JP]; TAMURA SEIKI [JP]; SOUDA TATSUO [JP]; HAYASHI AKITO [JP]; SAWAYAMA SAYURI [JP]; FURUKAWA HARUHIKO [JP]


Application No.: US20130096209A1  Published: 18/Apr/2013

Title: Compounds, Compositions, And Methods For Reducing Or Eliminating Bitter Taste

Applicant/Assignee: KRAFT FOODS GLOBAL BRANDS LLC, CHROMOCELL CORPORATION

Application No.: 13/641213   Filing Date: 15/Apr/2011

Abstract:

The present invention provides edible compositions comprising a compound of the present invention, food products comprising such edible compositions and methods of preparing such food products. The present invention also provides methods of reducing the amount of NaCl in a food product, methods of reducing the sodium intake in a diet, and methods of reducing bitter taste in a food product.

Priority: US2010-324416P Applic. Date: 2010-04-15; US2010-324407P Applic. Date: 2010-04-15; US2010-324367P Applic. Date: 2010-04-15; US2010-324364P Applic. Date: 2010-04-15; WO2011US32780 Applic. Date: 2011-04-15

Inventor: HAYASHI DAVID [US]; JONES WILLIAM P [US]; LELAND JANE V [US]; BROWN PETER H [US]; GUNNET JOSEPH [US]; LAVERY DANIEL [US]; SLADE LOUISE [US]; SHEKDAR KAMBIZ [US]; LANGER JESSICA [US]


Application No.: US20130098550A1  Published: 25/Apr/2013

Title: FUNCTIONALIZED ADHESIVE FOR MEDICAL DEVICES

Applicant/Assignee: COVIDIEN LP

Application No.: 13/637172   Filing Date: 24/Mar/2011

Abstract:

A method for adhering a medical device to biological tissue includes adhering an adhesive composition having a plurality of reactive members of a specific binding pair to tissue which has a plurality of complementary reactive members of the specific binding pair via click chemistry.

Priority: US2010-317456P Applic. Date: 2010-03-25; WO2011US29857 Applic. Date: 2011-03-24

Inventor: SARGEANT TIM [US]; HADBA ROBERT AHMAD [US]; STOPEK JOSHUA [US]


Application No.: US20130099410A1  Published: 25/Apr/2013

Title: EXTENDED RELEASE TABLET AND METHOD FOR MAKING AND USING SAME

Applicant/Assignee: CLARKE MOSQUITO CONTROL PRODUCTS, INC

Application No.: 13/709715   Filing Date: 10/Dec/2012

Abstract:

Provided are cap layer compositions and base layer compositions, providing quick and extended release of an active ingredient, respectively, when placed in water. Further provided are dual release compositions including a base composition and a cap composition. The base composition may include a plaster and an active agent, and it may further include at least one of a water-soluble binder, a non-water-soluble binder, and a lubricant. The cap composition may include a plaster and an active agent, and it may further include at least one of a disintegrating agent, a non-water-soluble binder, and a lubricant. The compositions may be heated and mixed and formed into a tablet. Further provided are methods of making the compositions. Further provided are methods of controlling or eliminating pests and methods of increasing the potability of water. The compositions are effective for controlling or eliminating pests such as mosquitoes when applied at an application site.

Priority: US2009-533937 Applic. Date: 2009-07-31; US2008-085315P Applic. Date: 2008-07-31; US2008-093054P Applic. Date: 2008-08-29

Inventor: WILLIS MICHAEL DEAN [US]; SAUNDERS MARIE ELIZABETH [US]


Application No.: US20130101516A1  Published: 25/Apr/2013

Title: NANOPARTICLES AND NANOPARTICLE COMPOSITIONS

Applicant/Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC

Application No.: 13/640698   Filing Date: 08/Apr/2011

Abstract:

The invention provides multivalent surface-crosslinked micelle (SCM) particles, crosslinked reverse micelle (CRM) particles, and methods of making and using them. The SCM particles can be used, for example, to inhibit a virus or bacteria from binding to a host cell. The inhibition can be used in therapy for the flu, cancer, or AIDS. The CRM particles can be used, for example, to prepare metal nanoparticles or metal alloy nanoparticles, or they can be used in catalytic reactions.

Priority: US2010-323072P Applic. Date: 2010-04-12; WO2011US31736 Applic. Date: 2011-04-08

Inventor: ZHAO YAN [US]


Application No.: US20130101531A1  Published: 25/Apr/2013

Title: ETHANOL-FREE AQUEOUS PERFUME COMPOSITION

Applicant/Assignee:

Application No.: 13/688668   Filing Date: 29/Nov/2012

Abstract:

The present invention relates to an ethanol-free, non-fatty, non-sticky perfumed aqueous cosmetic microemulsion composition, including one or more fragrance materials, a solvent, an aqueous medium, and optionally, one or more surfactants

wherein the solvent in the microemulsion is a vicinal diol such as 1,2-hexanediol.

Priority: US2006-579301 Applic. Date: 2006-11-01; WO2005US13564 Applic. Date: 2005-04-21; US2004-578099P Applic. Date: 2004-06-08

Inventor: SHICK REED A [US]; TUCKER CHRISTOPHER J [US]; PIECHOCKI CHRISTIAN [FR]; GATZ LETHA A [US]


Application No.: US20130101638A1  Published: 25/Apr/2013

Title: BONE SEMI-PERMEABLE DEVICE

Applicant/Assignee: SEARETE LLC

Application No.: 13/653629   Filing Date: 17/Oct/2012

Abstract:

Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects.

Priority: US2007-974852 Applic. Date: 2007-10-15; US2005-304486 Applic. Date: 2005-12-14; US2005-304492 Applic. Date: 2005-12-14; US2005-304499 Applic. Date: 2005-12-14

Inventor: HARLOW ED [US]; JUNG EDWARD K Y [US]; LANGER ROBERT [US]; LEUTHARDT ERIC C [US]; WOOD JR LOWELL L [US]


Application No.: US20130101639A1  Published: 25/Apr/2013

Title: BONE SEMI-PERMEABLE DEVICE

Applicant/Assignee: SEARETE LLC

Application No.: 13/653671   Filing Date: 17/Oct/2012

Abstract:

Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects.

Priority: US2007-974852 Applic. Date: 2007-10-15; US2005-304486 Applic. Date: 2005-12-14; US2005-304492 Applic. Date: 2005-12-14; US2005-304499 Applic. Date: 2005-12-14

Inventor: HARLOW ED [US]; JUNG EDWARD K Y [US]; LANGER ROBERT [US]; LEUTHARDT ERIC C [US]; WOOD JR LOWELL L [US]


Application No.: US20130101671A9  Published: 25/Apr/2013

Title: POLYPEPTIDE FOR TREATING OR PREVENTING ADHESIONS

Applicant/Assignee:

Application No.: 12/582516   Filing Date: 20/Oct/2009

Abstract:

The described invention provides compositions and methods for treating or preventing adhesions in a subject in need thereof, the method comprising the step of (a) administering an adhesion-reducing amount of a composition comprising a polypeptide having the amino acid sequence YARAAARQARAKALARQLGVAA [SEQ ID NO: 1] or a functional equivalent thereof and a carrier. The methods are clinically useful for reducing formation of adhesions initially and for therapeutic treatment of existing scars.

Priority: US2008-972459 Applic. Date: 2008-01-10; US2008-106834P Applic. Date: 2008-10-20; US2007-880137P Applic. Date: 2007-01-10

Inventor: PANITCH ALYSSA [US]


Application No.: US20130101674A1  Published: 25/Apr/2013

Title: BIOCIDAL COATING COMPOSITION

Applicant/Assignee: GX LABS HOLDINGS LIMITED

Application No.: 13/699884   Filing Date: 20/May/2011

Abstract:

The present invention relates to a biocidal coating composition comprising a biocide and an organofunctional silane oligomer which is distinct from the biocide. Such compositions are suitable for application to a substrate surface to provide long term disinfection on the surface of the substrate. The organofunctional silane oligomer prolongs the action of the biocide on the surface of the substrate, and provides improved surface-retention of the biocide.

Priority: GB20100008912 Applic. Date: 2010-05-27; WO2011GB50957 Applic. Date: 2011-05-20

Inventor: TOFT JOHN [GB]


Application No.: US20130101684A1  Published: 25/Apr/2013

Title: Compounds, Compositions, And Methods For Reducing Or Eliminating Bitter Taste

Applicant/Assignee: CHROMOCELL CORPORATION

Application No.: 13/641209   Filing Date: 15/Apr/2011

Abstract:

The present invention provides edible compositions comprising a compound of the present invention, food products comprising such edible compositions and methods of preparing such food products. The present invention also provides methods of reducing the amount of NaCl in a food product, methods of reducing the sodium intake in a diet, and methods of reducing bitter taste in a food product.

Priority: US2010-324362P Applic. Date: 2010-04-15; US2010-324359P Applic. Date: 2010-04-15; US2010-324351P Applic. Date: 2010-04-15; US2010-324346P Applic. Date: 2010-04-15; US2010-324345P Applic. Date: 2010-04-15; WO2011US32782 Applic. Date: 2011-04-15

Inventor: LELAND JANE V [US]; SLADE LOUISE [US]; HAYASHI DAVID [US]; JONES WILLIAM P [US]; BROWN PETER H [US]; GUNNET JOSEPH [US]; LAVERY DANIEL [US]; LANGER JESSICA [US]; SHEKDAR KAMBIZ [US]


Application No.: US20130102471A1  Published: 25/Apr/2013

Title: FORMULA COMPOSITION AS DELIVERY SYSTEM USED IN PHARMACEUTICAL AND PESTICIDE APPLICATIONS

Applicant/Assignee:

Application No.: 13/653926   Filing Date: 17/Oct/2012

Abstract:

The present invention is a formula composition that acts as an efficient delivery system to transport active components to their desired target sites in the bodies of human, animal, or plant species. This formula composition is comprised of d-Limonene (C10H16), Glycol EB (2-Butoxyethanol), Calimulse PRS (Benzenesulfonic acid, C10-16-alkyl derivatives, compounds with 2-propanamine), Calsoft L-60 (Benzenesulfonic acid, C10-16-alkyl derivatives, sodium salts, Sodium xylene sulfonate, sodium sulfate), Isopar M Solvent (Light Hydrotreated Petroleum Distillates), and water. This formula composition has both pharmaceutical and agricultural product applications, due to its ability to emulsify certain active components, preserve active components in their intact form, quickly deliver them to their target sites in the body, and increase their absorptions. The formula composition in the present invention performs above functions through the synergy of its components, as well as its excellent capacity of membrane transportation.

Priority: US201161549188P Applic. Date: 2011-10-19

Inventor: TIEU HUU [US]


Application No.: US20130102685A1  Published: 25/Apr/2013

Title: COMPOSITIONS COMPRISING A FLUOROSURFACTANT AND A HYDROTROPE

Applicant/Assignee: E.I. DU PONT DE NEMOURS AND COMPANY

Application No.: 13/279536   Filing Date: 24/Oct/2011

Abstract:

Compositions comprising a fluorosurfactant and a hydrotrope are disclosed. The hydrotropes are either cationic or anionic benzene derivatives comprising fluoro-substituted functional groups and polar groups. The compositions are useful in various surfactant applications.

Priority:

Inventor: CALVARESE THOMAS G [US]; GONZALEZ YAMAIRA [US]; PETROV VIACHESLAV A [US]; QIU WEIMING [US]; RAGHAVANPILLAI ANILKUMAR [US]


Application No.: US20130102686A1  Published: 25/Apr/2013

Title: Novel Organopolysiloxane, Surfactant, Emulsion Composition, Powder Treatment Agent, Thickening Agent Of Oil-Based Raw Material, Gelling Agent, Gel Composition, And Cosmetic Raw Material Comprising Novel Organopolysiloxane, As Well As, Preparation For External Use And Cosmetic Comprising The Same

Applicant/Assignee: DOW CORNING TORAY CO., LTD

Application No.: 13/643676   Filing Date: 28/Apr/2011

Abstract:

The present invention provides a novel organopolysiloxane in which a rich hydrophilic property is exhibited, not only superior miscibility with a hydrophilic component and but also a hydrophobic property are exhibited, and superior miscibility with both a silicone oil and a non-silicone oil such as a hydrocarbon oil, an ester oil or the like, and provide various usages of the aforementioned novel organopolysiloxane by developing the superior characteristics thereof such as good surface activity power, a distinctive sensation during use, increased stability and the like. A co-modified organopolysiloxane having a specified chemical structure in which a sugar alcohol-modified group and a long-chain hydrocarbon group are present in one molecule is produced. The co-modified organopolysiloxane is blended, as a surfactant, a powder treatment agent, a gelling agent or the like, or as a cosmetic raw material appropriately together with powder(s), oil agent(s) or the like, in a preparation for external use, and in particular, a cosmetic.

Priority: JP20100105889 Applic. Date: 2010-04-30; WO2011JP60803 Applic. Date: 2011-04-28

Inventor: TAMURA SEIKI [JP]; IIMURA TOMOHIRO [JP]; SOUDA TATSUO [JP]; HAYASHI AKITO [JP]; SAWAYAMA SAYURI [JP]; FURUKAWA HARUHIKO [JP]


Application No.: US20130109756A1  Published: 02/May/2013

Title: Dual Drug Delivery Using Silicone Gels

Applicant/Assignee: DOW CORNING CORPORATION

Application No.: 13/805894   Filing Date: 20/May/2011

Abstract:

Dual drug paste compositions are disclosed containing a silicone organic elastomer gel, a hydrophobic drug, and a hydrophilic drug. The dual drug paste compositions are useful for the simultaneous delivery of a hydrophobic and hydrophilic drug to a substrate without the drawbacks of using traditional gels, solutions or emulsions.

Priority: US2010-364134P Applic. Date: 2010-07-14; WO2011US37351 Applic. Date: 2011-05-20

Inventor: HUBER ROBERT [US]; MESSNER KATHRYN [US]; NARTKER LINDA [US]; RAUL VICTOR [US]; SCHALAU GERALD [US]


Application No.: US20130109761A1  Published: 02/May/2013

Title: OCTAHYDRO-1H-4,7-METHANO-INDENE-5-ALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS

Applicant/Assignee:

Application No.: 13/287594   Filing Date: 02/Nov/2011

Abstract:

The present invention is directed to a novel fragrance compound of octahydro-4,7-methano-1H-indene-5-acetaldehyde, octahydro-6-methyl-4,7-methano-1H-indene-5-carboxaldehyde, or a mixture thereof.

Priority:

Inventor: NARULA ANUBHAV P S [US]; LASOME JAMES ANTHONY [US]; WEISS RICHARD A [US]; MONTELEONE MICHAEL G [US]


Application No.: US20130115268A1  Published: 09/May/2013

Title: Methods of Administering a Dermatological Agent to a Subject

Applicant/Assignee: TEIKIKOKU SEIYAKU KABUSHIKI KAISHA, TEIKOKU PHARMA USA, INC

Application No.: 13/728582   Filing Date: 27/Dec/2012

Abstract:

Methods for administering a dermatological agent to a subject are provided. In the subject methods an effective amount of a topical formulation of the dermatological agent is topically applied to a host. The topically applied formulation of dermatological agent is then occluded with a hydrogel patch, where a feature of the hydrogel patch is that it lacks a pharmaceutically active agent. Also provided are methods of treating a subject for a disease condition by administering a dermatological agent to the subject. Also provided are kits for use in practicing the subject methods. The subject methods and compositions find use in a variety of different applications.

Priority: US2010-767638 Applic. Date: 2010-04-26; US2004-754477 Applic. Date: 2004-01-08; US2003-445572P Applic. Date: 2003-02-07

Inventor: KOO JOHN [US]; SHUDO JUTARO [US]; SHIRAI SADANOBU [JP]


Application No.: US20130115280A1  Published: 09/May/2013

Title: PHARMACEUTICAL AND/OR DIETARY COMPOSITIONS BASED ON SORT CHAIN FATTY ACIDS

Applicant/Assignee: COSMO TECHNOLOGIES LTD

Application No.: 13/810527   Filing Date: 13/Jul/2011

Abstract:

Pharmaceutical and/or dietary compositions based on short chain fatty acids or salts, esters and/or amides thereof in combination with one or more dietary soluble or water-dispersible fibre and at least one flavouring agent are disclosed.

Priority: RU20100132133 Applic. Date: 2010-07-29; IT2010MI01477 Applic. Date: 2010-08-03; WO2011EP61927 Applic. Date: 2011-07-13

Inventor: MORO LUIGI [IT]


Application No.: US20130116328A1  Published: 09/May/2013

Title: Thermogelling Anaesthetic Compositions

Applicant/Assignee: PHARMANEST AB

Application No.: 13/638511   Filing Date: 31/Mar/2011

Abstract:

The present invention relates to a thermogelling pharmaceutical composition comprising local anaesthetics in base form and which is suitable for topical administration. The compositions further comprise a polyoxyethylene castor oil and one or more surfactants to obtain thermogelling characteristics.

Priority: SE20100050321 Applic. Date: 2010-04-01; US2010-325481P Applic. Date: 2010-04-19; WO2011EP55009 Applic. Date: 2011-03-31

Inventor: SUNDBERG MARK [SE]; BRODIN ARNE [SE]; KAALLBERG NILS [SE]


Application No.: US20130116331A1  Published: 09/May/2013

Title: MEDICAL GEL

Applicant/Assignee: BRUSELLS VENTURES CORP

Application No.: 13/638080   Filing Date: 18/Jul/2011

Abstract:

This application pertains to antimicrobial medical gel compositions, the compositions comprising: (a) a gelling agent comprising etherified hydroxyethylcellulose

(b) an antimicrobial agent, specifically the quaternary ammonium compound benzalkonium chloride

(c) a solvent, propanediol being preferred

and (d) water. The compositions through their antimicrobial effectiveness address the problem of cross-contamination leading to infection, while meeting the criteria imposed upon medical gels used in ultrasound procedures which criteria include non-reflectiveness and non-refractiveness to ultrasound waves, pseudoplasticity, spreadability, adherence, acidity compatible with skin, minimal aeration, clarity, and resistance to drying. The medical gels function both as a lubricant and a couplant between a transducer and the skin, and find use in dermal ultrasound, physiotherapy, and medical aesthetic procedures.

Priority: US2010-365444P Applic. Date: 2010-07-19; WO2011CA00829 Applic. Date: 2011-07-18

Inventor: HEINAR THOMAS [CA]


Application No.: US20130116338A1  Published: 09/May/2013

Title: NANOMETAL DISPERSION AND METHOD FOR PREPARING THE SAME

Applicant/Assignee: CHINA MEDICAL UNIVERSITY

Application No.: 13/289439   Filing Date: 04/Nov/2011

Abstract:

A nanometal dispersion and a method for preparing a nanometal dispersion are provided. The method comprises the following steps: providing a first solution containing a metal ion

providing a second solution containing inulin

mixing the first solution and the second solution to provide a third solution

and providing energy to the third solution to conduct a reduction-oxidation reaction to form a nanometal therein. The produced nanometal dispersion comprises inulin and a nanometal with multimorphology.

Priority:

Inventor: CHOU CHIH-WEI [TW]; HOU YA-HSUN [TW]; KUO YUEH-HSIUNG [TW]; CHEN YUNG-HSIU [TW]


Application No.: US20130116340A1  Published: 09/May/2013

Title: Cosmetic And Topical Skin Preparation Comprising Higher Alcohol-Modified Silicone

Applicant/Assignee: DOW CORNING TORAY CO., LTD

Application No.: 13/643416   Filing Date: 27/Apr/2011

Abstract:

A cosmetic and a topical skin preparation comprising a higher alcohol-modified silicone (A) with the following general formula (1) wherein R1 is, e.g., an alkyl group

P is a monovalent organic group that contains the Si-O bond or is a long-chain monovalent hydrocarbyl group

at least one Q is a higher alcohol modifying group (-(C10-C30)-OH)

and (m1+m2+m3) is a number in the range from 0 to 55 and most favorably (m1+m2+m3) is 1.

Priority: JP20100104555 Applic. Date: 2010-04-28; WO2011JP60790 Applic. Date: 2011-04-27

Inventor: FURUKAWA HARUHIKO [JP]; HAYASHI AKITO [JP]; IIMURA TOMOHIRO [JP]


Application No.: US20130121970A1  Published: 16/May/2013

Title: METHOD FOR ELIMINATION OF SPACE THROUGH TISSUE APPROXIMATION

Applicant/Assignee: LIFECELL CORPORATION

Application No.: 13/671729   Filing Date: 08/Nov/2012

Abstract:

Acellular tissue matrix compositions for use in tissue approximation are provided. Also provided are methods for making and using the compositions to approximate tissue.

Priority: US201161558083P Applic. Date: 2011-11-10

Inventor: OWENS RICK [US]; XU HUI [US]; SUN WENQUAN [US]


Application No.: US20130121980A1  Published: 16/May/2013

Title: METHOD FOR SEPARATING COMPONENTS IN NATURAL OIL

Applicant/Assignee: ENGINEERING RESEARCH ASSOCIATES

Application No.: 13/297115   Filing Date: 15/Nov/2011

Abstract:

Different components of natural oils are separated by forming solid complexes of components of the natural oil with a solvent, and then separating the solid complexes from the remaining liquids. The natural oil is cooled in the presence of a solvent, and at least one component of the oil forms the solid complex with the solvent. This solid complex is separated from the remaining liquid portion of the oil solution, which also contains the solvent. Additional options concentration steps can further concentrate the components left in the liquid phase.

Priority:

Inventor: SONG YONGSHENG [US]


Application No.: US20130122073A1  Published: 16/May/2013

Title: COMPOSITION IN THE FORM OF LIQUID FOR MAINTENANANCE OF CONTACT LENSES AND MEDICAL MATERIALS

Applicant/Assignee: UNIWERSYTET JAGIELLONSKI

Application No.: 13/643484   Filing Date: 23/Apr/2011

Abstract:

The invention relates to a composition, particularly in the form of liquid to be used externally as a rinsing contact lenses, containing nanocrystalline photocatalyst active in visible light, and optionally hydrogen peroxide.

Priority: PL20100391056 Applic. Date: 2010-04-26; WO2011PL50011 Applic. Date: 2011-04-23

Inventor: LABUZ PRZEMYSLAW [PL]; MACCYK WOJCHIECH [PL]; STOCHEL GRAZYNA [PL]; HECZKO PIOTR [PL]; STRUS MAGDALENA [PL]


Application No.: US20130122094A1  Published: 16/May/2013

Title: SIALIC ACID ANALOGS

Applicant/Assignee: ULTRAGENYX PHARMACEUTICAL, INC

Application No.: 13/659550   Filing Date: 24/Oct/2012

Abstract:

The present invention provides sialic acid analogs and their compositions useful for the treatment of sialic acid deficiencies.

Priority: US201161550610P Applic. Date: 2011-10-24

Inventor: KAKKIS EMIL [US]; JUNGLES STEVEN [US]


Application No.: US20130122095A1  Published: 16/May/2013

Title: PLATELET-DERIVED GROWTH FACTOR COMPOSITIONS AND METHODS FOR THE TREATMENT OF OSTEOCHONDRAL DEFECTS

Applicant/Assignee: BIOMIMETIC THERAPEUTICS, INC

Application No.: 13/667566   Filing Date: 02/Nov/2012

Abstract:

The present invention provides compositions and methods for treating an osteochondral defect. In one embodiment, provided is a composition for treating an osteochondral defect comprising a biphasic biocompatible matrix and platelet derived growth factor (PDGF), wherein the biphasic biocompatible matrix comprises a scaffolding material and wherein the scaffolding material forms a porous structure comprising an osseous phase and a cartilage phase. In another embodiment, also provided is a method for treating an osteochondral defect in an individual comprising administering to the individual an effective amount of a composition comprising a biphasic biocompatible matrix and PDGF to at least one site of the osteochondral defect, wherein the biphasic biocompatible matrix comprises a scaffolding material and wherein the scaffolding material forms a porous structure comprising an osseous phase and a cartilage phase.

Priority: US2010-718942 Applic. Date: 2010-03-05; WO2010US26450 Applic. Date: 2010-03-05; US2009-209520P Applic. Date: 2009-03-05; US2009-164259P Applic. Date: 2009-03-27

Inventor: KESTLER HANS K [US]; NICKOLS JOSHUA [US]; WISNER-LYNCH LESLIE A [US]; RODEN COLLEEN M [US]; LIU YANCHUN [US]


Application No.: US20130122096A1  Published: 16/May/2013

Title: COMPOSITIONS FOR DRUG DELIVERY AND METHODS OF MANUFACTURING AND USING SAME

Applicant/Assignee: SILENSEED LTD

Application No.: 13/676540   Filing Date: 14/Nov/2012

Abstract:

Polymeric implants containing microparticles and nanoparticles, delivery of microparticles and nanoparticles from a polymeric implant is provided.

Priority: US201161629136P Applic. Date: 2011-11-14

Inventor: SHEMI AMOTZ [IL]; MALKA GABAI RACHEL [IL]


Application No.: US20130122112A1  Published: 16/May/2013

Title: Derivatized Hyperbranched Polyglycerols

Applicant/Assignee: CENTRE FOR DRUG RESEARCH AND DEVELOPMENT, THE UNIVERSITY OF BRITISH COLUMBIA

Application No.: 13/581463   Filing Date: 01/Mar/2011

Abstract:

Herein are provided derivatized hyperbranched polyglycerols ("dHPGs"). The dHPG comprises a core comprising a hyperbranched polyglycerol derivatized with C1C20 alkyl chains and a shell comprising at least one hydrophilic substituent bound to hydroxyl groups of the core, wherein the hyperbranched polyglycerol comprises from about 1 to about 200 moles of the at least one hydrophilic substituent. The dHPGs are for use as agents for the delivery of a drug or other biologically active moiety to the urinary tract, the digestive tract, the airways, the vaginal cavity and cervix and the peritoneal cavity to treat indications such as cancer, which may be useful in the treatment of or the manufacture of a medicament, in the preparation, of a pharmaceutical composition for the treatment of cancer, as a pre-treatment or co-treatment to improve drug uptake in a tissue. Furthermore, there are provided methods of making dHPGs.

Priority: US2010-309304P Applic. Date: 2010-03-01; WO2011CA00225 Applic. Date: 2011-03-01

Inventor: BURT HELEN M [CA]; BROOKS DONALD [CA]; KIZHAKKEDATHU JAYACHANDRAN [CA]; LIGGINS RICHARD [CA]; GUAN DECHI [CA]; YE LU [CA]; MUGABE CLEMENT [CA]; SO ALAN [CA]; GLEAVE MARTIN E [CA]; JACKSON JOHN K [CA]; KAINTHAN RAJESH KUMAR [US]


Application No.: US20130122120A1  Published: 16/May/2013

Title: INSECTICIDAL COMPOSITIONS AND METHODS

Applicant/Assignee:

Application No.: 13/676297   Filing Date: 14/Nov/2012

Abstract:

The present invention provides compositions that may be an aqueous insecticide containing at least one surfactant, such as for instance, sodium lauryl sulfate, at least one preservative, such as for instance, a potassium salt or sodium chloride, a nutrient source, such as for instance a yeast, an organic acid capable of lowering the pH of the aqueous insecticide, such as for instance citric acid, a fragrance, such as for instance geranium oil, and water. The aqueous insecticide may be designed to more efficiently kill and thereby control populations of species of Cimex, such as, for instance, Cimex lectularius.

Priority: US201161629156P Applic. Date: 2011-11-14

Inventor: ANGJELI EMIRA [US]


Application No.: US20130122467A1  Published: 16/May/2013

Title: PHOTOACTIVATABLE OXYGEN-EVOLVING COMPOSITIONS AND METHODS FOR TEETH WHITENING

Applicant/Assignee: KLOX TECHNOLOGIES INC

Application No.: 13/643672   Filing Date: 29/Apr/2011

Abstract:

Disclosed herein are compositions that can rapidly evolve oxygen and/or activated oxygen generally including an oxidizing agent (e.g., a peroxide) and an activating agent that has an emission wavelength between about 400 nm and about 570 nm (e.g., Eosin B, Eosin Y, or Erythrosine B). Methods of employing these compositions to whiten teeth, and methods of making these compositions and kits that include some or part of the composition ingredients, are also described.

Priority: US2010-771105 Applic. Date: 2010-04-30; US2006-598206 Applic. Date: 2006-11-09; WO2011CA50261 Applic. Date: 2011-04-29

Inventor: PIERGALLINI REMIGIO [IT]; LOUPIS NIKOLAOS [GR]


Application No.: US20130129616A1  Published: 23/May/2013

Title: GEL COMPOSITION FOR FILLING A BREAST MILK DUCT PRIOR TO SURGICAL EXCISION OF THE DUCT OR OTHER BREAST TISSUE

Applicant/Assignee:

Application No.: 13/659819   Filing Date: 24/Oct/2012

Abstract:

The invention is a gel composition for delivery to a breast milk duct prior to surgical excision of breast tissue including cancerous lesions. The invention also provides methods of mapping all or nearly all of a breast milk duct prior to surgical excision of breast tissue, and method of identifying part or all of a breast duct or ducts as a surgical aide to a breast surgeon. Kits to support these methods and including these compositions are also provided.

Priority: US201113093781 Applic. Date: 2011-04-25; US2007-725928 Applic. Date: 2007-03-20; US2003-425177 Applic. Date: 2003-04-29; US2000-590517 Applic. Date: 2000-06-09; US1999-138693P Applic. Date: 1999-06-11

Inventor: BIANCHI ANNETTE [US]; NIKOLCHEV JULIAN [US]; HUNG DAVID [US]; RON EYAL [US]; GONT LINDA K [US]; LOVE SUSAN [US]; PATEL TINA [US]


Application No.: US20130129825A1  Published: 23/May/2013

Title: DIVERSION-RESISTANT MICROGRANULES AND MICROTABLETS

Applicant/Assignee: ETHYPHARM

Application No.: 13/702787   Filing Date: 07/Jun/2011

Abstract:

The invention relates to the use of an oral dosage form based on microgranules and/or microtablets to reduce the abusive use of at least one active principle contained therein. The aim of the invention is to prevent the diversion of an oral dosage form based on microgranules and/or microtablets containing at least one active principle capable of causing a dependency, a gelling agent, and a gelling activator. The gelling agent and the activator are only brought into contact with each other in the event of diversion by crushing. Said judiciously selected pair of excipients confers a viscosity to the formulation, such that said formulation cannot be administered by injection or does not release the active principle rapidly by forming a gel when it comes into contact with the mucous membrane if nasally administered.

Priority: FR20100054465 Applic. Date: 2010-06-07; FR20100055921 Applic. Date: 2010-07-20; WO2011EP59410 Applic. Date: 2011-06-07

Inventor: BILLOET VINCENT [FR]


Application No.: US20130129827A1  Published: 23/May/2013

Title: EXTENDED RELEASE PHARMACEUTICAL COMPOSITIONS OF PALIPERIDONE AND PROCESSES OF PREPARATION THEREOF

Applicant/Assignee: RANBAXY LABORATORIES LIMITED

Application No.: 13/502016   Filing Date: 18/Oct/2010

Abstract:

The present invention relates to extended release pharmaceutical compositions of paliperidone and process of preparation thereof.

Priority: IN2009DE02150 Applic. Date: 2009-10-16; WO2010IB54714 Applic. Date: 2010-10-18

Inventor: VIVEK KUMARAVEL [IN]; VERMA RAJAN KUMAR [IN]; SINGH ROMI BARAT [IN]


Application No.: US20130130912A1  Published: 23/May/2013

Title: AGROCHEMICAL FORMULATION COMPOSITION

Applicant/Assignee: HUNTSMAN INTERNATIONAL LLC

Application No.: 13/809183   Filing Date: 12/Jul/2011

Abstract:

The invention relates to an agrochemical formulation composition. The agrochemical formulation composition comprising at least one agrochemical active component and a solvent, which solvent comprises one or more dialkyl carbonates of the formula CO(ORa)(ORb), each of Ra and Rb being a linear or branched alkyl group of 3 to 6 carbon.

Priority: EP20100170019 Applic. Date: 2010-07-19; WO2011EP61871 Applic. Date: 2011-07-12

Inventor: TANNIR BASSAM [BE]; VAN DER SANDE KAREN [BE]; SAYLIK DILEK [AU]; PARIS EMMANUEL [BE]; VANDERSTRAETEN PETRA EMMA [BE]


Application No.: US20130131188A1  Published: 23/May/2013

Title: Cosmetic Preparations

Applicant/Assignee: COGNIS IP MANAGEMENT GMBH

Application No.: 13/813719   Filing Date: 22/Jul/2011

Abstract:

The invention relates to compounds of the general formula (I), where R1 is a branched alkyl(ene) radical having from 10 to 22 carbon atoms and having at least one branch in position 1, 2, 3 or 4 relative to the oxygen atom, R2 is a linear or branched alkyl(ene) radical having from 1 to 13 carbon atoms and R1 and R2 are selected so that the total number of carbon atoms in formula (I) is from 11 to 23. The compounds of the invention are suitable for preparation of or in cosmetic and/or pharmaceutical preparations, in particular as oily substances. R1-O-R2(I)

Priority: EP20100172065 Applic. Date: 2010-08-05; WO2011EP03670 Applic. Date: 2011-07-22

Inventor: BECKEDAHL BURKHARD [DE]; DIERKER MARKUS [DE]; KAWA ROLF [DE]; BRUENING STEFAN [DE]


Application No.: US20130136784A1  Published: 30/May/2013

Title: METHODS FOR DELIVERY OF MEDICATION USING DISSOLVABLE DEVICES

Applicant/Assignee:

Application No.: 13/747607   Filing Date: 23/Jan/2013

Abstract:

A method utilizing a dissolvable device for the internal delivery of medication and more particularly to the use of fibers or non-woven fabrics made of a safe polymer material incorporating a medication that is released by dissolution of the fibers or non-woven fabrics over time, and more particularly a treatment method for controlling or regulating the pH in the vagina by stabilizing and adjusting the pH in the vagina by minimizing the impact of the vaginal flora.

Priority: US2009-587985 Applic. Date: 2009-10-16; US2008-287253 Applic. Date: 2008-10-08; US2007-998383P Applic. Date: 2007-10-11

Inventor: STAAB ROBERT J [US]


Application No.: US20130136795A1  Published: 30/May/2013

Title: SOLID VALSARTAN COMPOSITION

Applicant/Assignee: POLIGONO MERCK, GENERICS [UK] LIMITED

Application No.: 12/671269   Filing Date: 08/Aug/2008

Abstract:

The present invention relates to stable solid pharmaceutical compositions comprising valsartan as the active pharmaceutical ingredient. Optionally the compositions comprise one or more further active pharmaceutical ingredients. The invention further relates to methods for preparing said compositions and to the use of said compositions in the treatment or prevention of angiotensin receptor mediated disorders, in particular hypertension and related disorders.

Priority: GB20070015628 Applic. Date: 2007-08-10; WO2008GB50687 Applic. Date: 2008-08-08

Inventor: BARRERO MIGUEL [ES]; DELGADO ISABEL [ES]


Application No.: US20130136796A1  Published: 30/May/2013

Title: Acellular Bioabsorbable Tissue Regeneration Matrices

Applicant/Assignee:

Application No.: 13/617150   Filing Date: 14/Sep/2012

Abstract:

The present invention provides methods and compositions useful in the regeneration of damaged, lost and/or degenerated tissue in humans and animals. In certain embodiments, the present invention provides an acellular bioabsorbable tissue regeneration matrix, methods of making such a matrix, and methods of using such a matrix for the regeneration of damaged, lost and/or degenerated tissue. In certain embodiments, methods and compositions of the present invention are useful in the treatment of damaged, lost and/or degenerated nerve tissue.

Priority: US2006-588840 Applic. Date: 2006-10-26; US2005-730614P Applic. Date: 2005-10-26

Inventor: AHLFORS JAN-ERIC [AG]


Application No.: US20130137670A1  Published: 30/May/2013

Title: ZWITTERION SOLUTION FOR LOW-VOLUME THERAPEUTIC DELIVERY

Applicant/Assignee: WAYNE STATE UNIVERSITY BOARD OF GOVERNORS

Application No.: 13/750566   Filing Date: 25/Jan/2013

Abstract:

A formulation is provided that includes a volume of an aqueous multivalent physiological ion solution compatible with cerebrospinal fluid containing at least one divalent cation of magnesium or calcium, and at least one anion of carbonate or phosphate, and having a pH between 6.5 and 8.0. A zwitterionic therapeutic agent other than baclofen is dissolved the solution to achieve higher concentration or ease of solution and/or storage relative to therapeutic saline solutions of the same agent. A process of delivering a zwitterionic therapeutic agent into a subject is provided that includes dissolving a therapeutic amount of the zwitterionic therapeutic agent in a volume of artificial cerebrospinal fluid to form a stable formulation. The solution is then administered to the subject using an intrathecal pump.

Priority: US2010-664507 Applic. Date: 2010-04-27; WO2008US66855 Applic. Date: 2008-06-13; US2007-943732P Applic. Date: 2007-06-13

Inventor: MEYTHALER JAY M [US]


Application No.: US20130137741A1  Published: 30/May/2013

Title: Pharmaceutical Composition for Delivery of Receptor Tyrosine Kinase Inhibiting (RTKi) Compounds to the Eye

Applicant/Assignee: ALCON RESEARCH, LTD

Application No.: 13/749887   Filing Date: 25/Jan/2013

Abstract:

The present invention relates to development of efficacious pharmaceutical compositions in the form of aqueous solutions comprising an active agent in a therapeutically effective amount and a polyethylene glycol having a molecular weight of at least 2000.

Priority: US2010-716663 Applic. Date: 2010-03-03; US2009-156922P Applic. Date: 2009-03-03

Inventor: KABRA BHAGWATI P [US]; GHOSH MALAY [US]


Application No.: US20130142875A1  Published: 06/Jun/2013

Title: METHODS AND COMPOSITIONS FOR TREATING PROSTATE CANCER

Applicant/Assignee: SILENSEED LTD

Application No.: 13/676581   Filing Date: 14/Nov/2012

Abstract:

Treatment of prostate cancer by regional and prolonged release of one or more nucleotide-based RNAi agents is provided.

Priority: US201161629135P Applic. Date: 2011-11-14

Inventor: SHEMI AMOTZ [IL]; ZORDE KHVALEVSKY ELINA [IL]; MALKA GABAI RACHEL [IL]


Application No.: US20130142876A1  Published: 06/Jun/2013

Title: AMPHIPATHIC LIPID-BASED SUSTAINED RELEASE COMPOSITIONS

Applicant/Assignee: PEGASUS LABORATORIES, INC

Application No.: 13/690974   Filing Date: 30/Nov/2012

Abstract:

Chewable sustained release compositions and their methods of production are provided. The sustained release compositions contain amphipathic lipids, which are used to encapsulate various drugs and active ingredients.

Priority: US201161566279P Applic. Date: 2011-12-02

Inventor: HOWARD SCOTT A [US]; PURVIS TROY [US]


Application No.: US20130144239A1  Published: 06/Jun/2013

Title: LOTIONS DERIVED FROM RENEWABLE RESOURCES AND ABSORBENT ARTICLES COMPRISING SAME

Applicant/Assignee: THE PROCTER & GAMBLE COMPANY

Application No.: 13/739118   Filing Date: 11/Jan/2013

Abstract:

A lotion having an emollient and an immobilizing agent. The emollient is derived from a renewable resource and having a bio-based content of from about 10% to about 100% using ASTM D6866-10, method B and the immobilizing agent selected from the group consisting of C14-C60 fatty alcohols, C14-C60 fatty acids, C14-C60 fatty alcohol ethoxylates having an average degree of ethoxylation ranging from about 2 to about 110, waxes and mixtures thereof. Absorbent articles comprising said lotions are also provided for herein.

Priority: US201113182028 Applic. Date: 2011-07-13

Inventor: WARREN RAPHAEL [US]; WEISMAN PAUL THOMAS [US]


Application No.: US20130149318A1  Published: 13/Jun/2013

Title: PAINTING THE PIA, ARACHNOID, AND SPINAL CORD PARENCHYMA

Applicant/Assignee: INVIVO THERAPEUTICS CORPORATION

Application No.: 13/714081   Filing Date: 13/Dec/2012

Abstract:

A PEG based hydrogel and a procedure for its topical application to the surface of the pia mater of the spinal cord that can be used for intrathecal delivery of diverse drug and biomolecular therapies for the treatment of traumatic central nervous system injuries and disorders including spinal cord injury (SCI), multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS) are provided. This "painting of the pia" with biofunctionalized hydrogel material may be used as a prelude strategy in the therapeutic management of these CNS disorders. The strategy may be designed to create a microenvironment within the damaged regions of the spinal cord that is more conducive to the successful application of subsequent regeneration based treatments such as cell replacement therapies or endogenous regeneration and plasticity stimulation via application of growth factors or gene therapy. Compositions and methods for topical application of the PEG based hydrogel to the arachnoid mater, the intrathecal portions of the spinal nerves, and application directly to the spinal cord parenchyma are also provided.

Priority: US201161570155P Applic. Date: 2011-12-13

Inventor: REYNOLDS FRANCIS M [US]; LANGER ROBERT S [US]; SLOTKIN JONATHAN R [US]; WIRTH III EDWARD D [US]; O'SHEA TIMOTHY [US]; AIMETTI ALEX [US]


Application No.: US20130149356A1  Published: 13/Jun/2013

Title: Muscle-based grafts/implants

Applicant/Assignee: RTI BIOLOGICS, INC

Application No.: 13/815184   Filing Date: 07/Feb/2013

Abstract:

The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic agent to attract a desired cell.

Priority: US2010-807599 Applic. Date: 2010-09-09; US2007-949687 Applic. Date: 2007-12-03; US2006-480711 Applic. Date: 2006-07-03; US2004-793976 Applic. Date: 2004-03-05; US2004-754310 Applic. Date: 2004-01-09

Inventor: MILLS C RANDAL [US]; BIANCHI JOHN R [US]; ROBERTS MICHAEL R [US]; CHEUNG DAVID T [US]; NATARAJ CHANDRASEKARAN [US]; HOWELL JOHN W [US]


Application No.: US20130149357A1  Published: 13/Jun/2013

Title: Porous Degradable Polyelectrolyte Microspheres as Vaccine Vector

Applicant/Assignee:

Application No.: 13/818263   Filing Date: 24/Aug/2011

Abstract:

The present invention discloses a composition comprising a polyelectrolyte complex and a polyol, characterised in that said polyol is in amorphous form. Optionally, the composition further comprises one or more drugs, wherein each drug has a molecular weight of at least 1000 Dalton. Said compositions are obtainable by spray-drying. The compositions may be prepared in particle form and as a suspension of particles. Pharmaceutical compositions are also provided for use in extracellular drug delivery. Pharmaceutical compositions are also provided that exhibit a controlled dual drug release.

Priority: GB20100014121 Applic. Date: 2010-08-24; WO2011EP64507 Applic. Date: 2011-08-24

Inventor: REMON JEAN PAUL [BE]; DE GEEST BRUNO [BE]; DE KOKER STEFAAN [BE]; GROOTEN JOHAN [BE]; VERVAET CHRIS [BE]


Application No.: US20130150241A1  Published: 13/Jun/2013

Title: SPRAY DRIFT REDUCTION AGENTS COMPRISING LOW HYDROPHILIC-LIPOPHILIC BALANCE SURFACTANTS

Applicant/Assignee: HUNTSMAN PETROCHEMICAL LLC

Application No.: 13/696826   Filing Date: 05/Apr/2012

Abstract:

Embodiments of the present invention disclose using low hydrophilic-lipophilic balance surfactants as spray drift reduction agents and methods of using such agents.

Priority: US201161477251P Applic. Date: 2011-04-20; WO2012US32265 Applic. Date: 2012-04-05

Inventor: ELSIK CURTIS M [US]


Application No.: US20130150311A1  Published: 13/Jun/2013

Title: MIXED POLOXAMER EXCIPIENTS

Applicant/Assignee:

Application No.: 13/324395   Filing Date: 13/Dec/2011

Abstract:

In one aspect, the present invention is directed to a dry, flowable and compressible composition, useful as a pharmaceutical excipient, which composition comprises a mixture of hydrophobic and hydrophilic poly(ethylene oxide)-polypropylene oxide)-poly(ethylene oxide) block copolymers, and which possesses a Carr index of less than about 20. In other aspects, the present invention is directed a pharmaceutical composition comprising such adjuvant and a pharmaceutically active ingredient

as well as to a method of making the compositions.

Priority:

Inventor: PIETRZYNSKI GRZEGORZ [CA]; ALAKHOV VALERY [CA]; PATEL KISHORE [CA]


Application No.: US20130150313A1  Published: 13/Jun/2013

Title: METHOD FOR DISINFECTING SURFACES

Applicant/Assignee: JOKER AG

Application No.: 13/643522   Filing Date: 16/Mar/2011

Abstract:

A malleable compound according to the invention for use as a disinfectant comprises water, 25 to 40% by weight of a solvent component comprising low-molecular, water-miscible alcohols, 1 to 10% by weight of an active bactericidal component, 3 to 6% by weight hydroxypropylated polygalactomannan with an etherification level of between 0.3 and 1.5 and 0.1 to 0.5% by weight boracic acid or an equivalent amount of boron ions.

Priority: CH20100000600 Applic. Date: 2010-04-26; WO2011EP53921 Applic. Date: 2011-03-16

Inventor: FLURY MEINRAD [CH]; DIETRICH RENE H [CH]


Application No.: US20130150458A1  Published: 13/Jun/2013

Title: SILICONE-MODIFIED WAX, COMPOSITION AND COSMETIC PREPARATION CONTAINING THE SAME, AND PRODUCTION METHOD OF SILICONE-MODIFIED WAX

Applicant/Assignee: SHIN-ETSU CHEMICAL CO., LTD

Application No.: 13/705593   Filing Date: 05/Dec/2012

Abstract:

The present invention provides a silicone-modified wax obtained by subjecting an esterification reaction product obtained from a polyhydric alcohol having one or two alkenyl groups in one molecule and a higher fatty acid, and an organohydrogenpolysiloxane containing at least one methyl group, to a hydrosilylation reaction

wherein the silicone-modified wax is solid or in a grease state exhibiting a thixotropy, at 25 DEG C. There can be a silicone-modified wax, a production method thereof, and a composition and a cosmetic preparation each containing the silicone-modified wax, which silicone-modified wax is solid or in a grease state exhibiting a thixotropy, at 25 DEG C., and is high in compatibility with oil-based agents such as volatile and nonvolatile silicone oils, hydrocarbon oils, ester oils, natural animal oils and plant oils, and the like.

Priority: JP20110268374 Applic. Date: 2011-12-07

Inventor: IYOKU HIROOMI [JP]


Application No.: US20130150464A1  Published: 13/Jun/2013

Title: STABILIZED POLYPHENOL SOLUTION AND METHOD FOR STABILIZING POLYPHENOL SOLUTION

Applicant/Assignee: MENICON CO., LTD

Application No.: 13/765093   Filing Date: 12/Feb/2013

Abstract:

There are provided a stabilized polyphenol solution which is applicable as various contact lens solutions and has high lens compatibility and safety, and further also a method for stabilizing such a polyphenol solution. At least one inorganic salt-free buffer is contained in a concentration of 0.001-5% by weight in an aqueous solution containing at least one polyphenol, at least one polyol is further contained therein in a concentration of 0.01-5% by weight to prepare a solution so as to contain no inorganic salt, and the pH of the solution is adjusted to 7.3 or less.

Priority: WO2010JP65053 Applic. Date: 2010-09-02

Inventor: HISHIKAWA YURI [JP]; OGAWA SUSUMU [JP]


Application No.: US20130150883A1  Published: 13/Jun/2013

Title: HEMOSTATIC DEVICE

Applicant/Assignee:

Application No.: 13/706987   Filing Date: 06/Dec/2012

Abstract:

A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.

Priority: US201161568946P Applic. Date: 2011-12-09

Inventor: FETTE CLAY [US]; JANIS ABRAM [US]; KIBALO BENJAMIN [US]


Application No.: US20130156712A1  Published: 20/Jun/2013

Title: STABLE SURFACTANT COMPOSITIONS FOR SUSPENDING COMPONENTS

Applicant/Assignee: RHODIA OPERATIONS

Application No.: 13/767628   Filing Date: 14/Feb/2013

Abstract:

A free-flowing surfactant composition comprising at least one anionic surface-active agent, an alkanolamide, an electrolyte, and water is described. In particular, the composition is a surfactant composition that has free-flowing non-Newtonian shear thinning properties and the ability to suspend components and is stable under at least one freeze/thaw cycle.

Priority: US2010-965389 Applic. Date: 2010-12-10; US2002-324371 Applic. Date: 2002-12-20; US2001-341845P Applic. Date: 2001-12-21; US2002-369216P Applic. Date: 2002-04-01

Inventor: FRANTZ SEREN [US]; COTRELL PHILLIP L [US]; WARBURTON STEWART A [US]


Application No.: US20130156871A1  Published: 20/Jun/2013

Title: Nasal Wash Solution

Applicant/Assignee: WATER PIK, INC

Application No.: 13/722748   Filing Date: 20/Dec/2012

Abstract:

A composition provides an isotonic nasal irrigation solution with pH less than about 7.0. The composition may be formed of a salt and a pH buffer and may include an additive. The composition may be mixed with water to form the solution. The composition may aid in the treatment of various nasal or sinus disorders such as, for example, dryness, rhinitis, and sinusitis. The isotonic irrigation solution may also aid in the removal of contaminants from the sinus and nasal cavities such as blood, mucus, dirt, pollen, allergens, viruses, and bacterial. The composition may be liquid or dry.

Priority: US201161577945P Applic. Date: 2011-12-20

Inventor: KELLER TED [US]


Application No.: US20130164238A1  Published: 27/Jun/2013

Title: COSMETIC AEROSOL SPRAY

Applicant/Assignee: HENKEL AG & CO. KGAA

Application No.: 13/772913   Filing Date: 21/Feb/2013

Abstract:

A cosmetic product includes a water-in-oil emulsion containing: a) at least one cosmetic active ingredient, b) at least one water-in-oil emulsifier, c) at least one non-ionic polyalkylene glycol ether having a HLB value >7, d) at least one C8-C16 isoparaffin, and also including at least one propellant and an aerosol dispensing device. The emulsion has a high stability, a reduced susceptibility to corrosion, a good cosmetic effect and reduced formation of deposits during the application thereof.

Priority: DE20101040121 Applic. Date: 2010-09-01; WO2011EP65043 Applic. Date: 2011-08-31

Inventor: BANOWSKI BERNHARD [DE]; SCHNELDER NADINE [DE]


Application No.: US20130164335A1  Published: 27/Jun/2013

Title: METHODS AND COMPOSITIONS FOR CELLULAR DRUG RELEASE

Applicant/Assignee: NATIONAL HEALTH RESEARCH INSTITUTES

Application No.: 13/338073   Filing Date: 27/Dec/2011

Abstract:

Methods and compositions for producing a cellular drug release are disclosed. The method comprises: a) providing a composition comprising a therapeutically effective amount of a pharmacological agent adsorbed onto mesoporous hydroxyapatite (HAP) with hydrophobic surfaces

b) exposing the composition to a cell

c) causing entry of the mesoporous HAP into the cell and degradation of the HAP in the lysosomes of the cell and desorption of the agent from the mesoporous HAP

d) causing release of the desorbed agent from the lysosomes into the cytoplasm of the cell

and e) causing release of the desorbed agent to outside the cell. The composition comprises a) mesoporous HAP with hydrophobic surfaces

and b) a therapeutically effective amount of a pharmacological agent, adsorbed onto the hydrophobic surfaces of the mesoporous. HAP. The composition is characterized in that it constantly releases the agent in vivo for a period of at least 4 weeks.

Priority:

Inventor: CHEN CHENG [TW]; LIN FENG-HUEI [TW]


Application No.: US20130164354A1  Published: 27/Jun/2013

Title: METHOD FOR THE EXTEMPORANEOUS PREPARATION OF COSMETIC COMPOSITIONS HAVING THE TEXTURE OF A CREAM AND COMPOSITIONS FOR CARRYING OUT SAID METHOD

Applicant/Assignee:

Application No.: 13/545676   Filing Date: 10/Jul/2012

Abstract:

Disclosed is a method for the preparation of cosmetic compositions having the texture of a cream. Said preparation is made at the time when the composition is used and includes bringing into contact with each other (A) a liquid phase, (B) a powder containing a gelling agent for the liquid phase (A), and (C) an active cosmetic ingredient, whereby the elements are brought into contact by adding phase (A) to phase (B), subjecting a solid powder containing phase (B) and phase (A) in an immobilized form to mechanical stress to release phase (A). Further disclosed are compositions comprising phase (B) and phase (A) in an immobilized form which are transformed into a cream when applied to the skin).

Priority: FR20020011515 Applic. Date: 2002-09-17; US2005-527948 Applic. Date: 2005-11-14; WO2003FR02732 Applic. Date: 2003-09-16

Inventor: SEU-SALERNO MARTINE [FR]; FILLARDET LAURENCE [FR]; BOULIER VIRGINIE [FR]


Application No.: US20130164377A1  Published: 27/Jun/2013

Title: SHELL-AND-CORE DOSAGE FORM APPROACHING ZERO-ORDER DRUG RELEASE

Applicant/Assignee: DEPOMED, INC

Application No.: 13/688114   Filing Date: 28/Nov/2012

Abstract:

Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core by permitting diffusion of the drug from the core. The shell also motes gastric retention of the dosage form by swelling upon imbibition of gastric fluid to size that is retained in the stomach during the postprandial or fed mode.

Priority: US201113156225 Applic. Date: 2011-06-08; US2010-770283 Applic. Date: 2010-04-29; US2002-213823 Applic. Date: 2002-08-07; US2000-498945 Applic. Date: 2000-02-04

Inventor: BERNER BRET [US]; LOUIE-HELM JENNY [US]; GUSLER GLORIA [US]; SHELL JOHN W [US]


Application No.: US20130165531A1  Published: 27/Jun/2013

Title: Anthocyanin based colorant compositions

Applicant/Assignee: E.P.C. (BEIJING) PLANT PHARMACEUTICAL TECHNOLOGY CO., LTD

Application No.: 13/507186   Filing Date: 12/Jun/2012

Abstract:

The invention describes novel aluminum based aqueous anthocyanin solutions, methods to prepare them and the compositions thereof.

Priority: US201161496118P Applic. Date: 2011-06-13; US201261689726P Applic. Date: 2012-06-11

Inventor: SHI JINGANG [CN]; MA HUI [CN]; JIN ZHIJIN [CN]


Application No.: US20130165532A1  Published: 27/Jun/2013

Title: NOVEL DECENAL MIXTURES AND THEIR USE IN PERFUME COMPOSITIONS

Applicant/Assignee: INTERNATIONAL FLAVORS & FRAGRANCES INC

Application No.: 13/369420   Filing Date: 09/Feb/2012

Abstract:

The present invention relates to a novel decenal mixture and the incorporation and use of this mixture as a fragrance material. The novel decenal mixture contains decenals that are represented by the formula set forth below: wherein the broken line represents one double bond and two single bonds.

Priority: US201161579642P Applic. Date: 2011-12-22

Inventor: NARULA ANUBHAV P S [US]; ARRUDA EDWARD MARK [US]; SCHIET FRANC T [NL]


Application No.: US20130171080A1  Published: 04/Jul/2013

Title: PERSONAL CARE COMPOSITIONS CONTAINING END-FUNCTIONALIZED IONIC SILICONE

Applicant/Assignee: MOMENTIVE PERFORMANCE MATERIALS INC

Application No.: 13/733482   Filing Date: 03/Jan/2013

Abstract:

A personal care composition contains at least one personal care component and at least one end-functionalized ionic silicone.

Priority: US201261582914P Applic. Date: 2012-01-04

Inventor: SARKAR ALOK [US]; SAXENA ANUBHAV [IN]; TIWARI SANDIP [IN]; FALK BENJAMIN [US]


Application No.: US20130171240A1  Published: 04/Jul/2013

Title: DRUG CARRIER AND DRUG CARRIER KIT FOR INHIBITING FIBROSIS

Applicant/Assignee: NITTO DENKO CORPORATION

Application No.: 13/786883   Filing Date: 06/Mar/2013

Abstract:

Disclosed is a stellate cell-specific drug carrier comprising a stellate cell-specific amount of a retinoid derivative and/or a vitamin A analogue, and a drug carrier component other than the retinoid derivative and/or a vitamin A analogue. Also disclosed in a medicine comprising the stellate cell-specific drug carrier, and a drug in an amount effective for controlling the activity or growth of stellate cells.

Priority: JP20040382791 Applic. Date: 2004-12-22; US201213439330 Applic. Date: 2012-04-04; US2008-793736 Applic. Date: 2008-04-08; WO2005JP23619 Applic. Date: 2005-12-22; US201213492424 Applic. Date: 2012-06-08; US201161494840P Applic. Date: 2011-06-08

Inventor: NIITSU YOSHIRO [JP]; KATO JUNJI [JP]; SATO YASUSHI [JP]; PAYNE JOSEPH E [US]; GAUDETTE JOHN A [US]; HOU ZHENG [US]; KNOPOV VICTOR [US]; WITTE RICHARD P [US]; AHMADIAN MOHAMMAD [US]; PERELMAN LOREN A [US]; TANAKA YASUNOBU [JP]; AKOPIAN VIOLETTA [US]


Application No.: US20130171256A1  Published: 04/Jul/2013

Title: ALCOHOL-RESISTANT EXTENDED RELEASE DOSAGE FORMS COMPRISING VENLAFAXINE

Applicant/Assignee: CIMA LABS INC

Application No.: 13/715698   Filing Date: 09/May/2011

Abstract:

This disclosure relates to an extended release oral dosage form comprising a matrix containing a viscosity modifier (but no lipid) and coated granules containing venlafaxine or a pharmaceutically acceptable salt or solvate thereof. The dosage form has alcohol resistance and may also have crush resistance.

Priority: US2010-333527P Applic. Date: 2010-05-11; WO2011US35768 Applic. Date: 2011-05-09

Inventor: HAMED EHAB [US]


Application No.: US20130172194A1  Published: 04/Jul/2013

Title: FORMULATION

Applicant/Assignee: SYNGENTA CROP PROTECTION LLC

Application No.: 13/540310   Filing Date: 02/Jul/2012

Abstract:

Agrochemical concentrates having a continuous water-containing single phase, where said continuous phase also comprises an oil-based adjuvant and a hydrotrope capable of solubilising said adjuvant in said continuous phase, a process for making these concentrates and a method of using these concentrates.

Priority: GB20030018448 Applic. Date: 2003-08-06; US2004-567230 Applic. Date: 2004-08-06; WO2004GB03424 Applic. Date: 2004-08-06

Inventor: BELL GORDON ALASTAIR [GB]; RAMSAY GUY [GB]


Application No.: US20130172357A1  Published: 04/Jul/2013

Title: Compositions and Methods for Treatment of Glaucoma

Applicant/Assignee: EYE THERAPIES LLC

Application No.: 13/760026   Filing Date: 05/Feb/2013

Abstract:

The invention provides alpha-2 adrenergic receptor agonist compositions and methods for treating glaucoma and other intraocular conditions. The preferred alpha-2 agonist used in the inventive compositions and methods is dexmedetomidine.

Priority: US201213585602 Applic. Date: 2012-08-14; US201213365138 Applic. Date: 2012-02-02; US2011-931632 Applic. Date: 2011-02-03

Inventor: HORN GERALD [US]


Application No.: US20130172374A1  Published: 04/Jul/2013

Title: SOLID COMPOSITION FOR CONTROLLED RELEASE OF IONIZABLE ACTIVE AGENTS WITH POOR AQUEOUS SOLUBILITY AT LOW PH AND METHODS OF USE THEREOF

Applicant/Assignee: PORTOLA PHARMACEUTICALS, INC

Application No.: 13/633055   Filing Date: 01/Oct/2012

Abstract:

A novel solid composition and methods for making and using the solid composition are provided. The solid composition comprises: (a) at least one active agent with a solubility of less than about 0.3 mg/ml in an aqueous solution with a pH of at most about 6.8 at a temperature of about 37 DEG C.

and (b) a hydrophilic polymer matrix composition comprising: i) a hydrophilic polymer selected from the group consisting of METHOCEL(TM), POLYOX(TM) WSR 1105 and combinations thereof

and optionally ii) a hydrophobic polymer selected from the group consisting of Ethocel 20 premium

and (c) an alkalizer selected from the group consisting of calcium carbonate, magnesium oxide heavy and sodium bicarbonate

wherein the composition provides at least about 70% release of the active between about 7 to about 12 hours following oral administration.

Priority: US2009-618511 Applic. Date: 2009-11-13; US2008-115008P Applic. Date: 2008-11-14; US2008-114941P Applic. Date: 2008-11-14

Inventor: RAMANI CHANDIR [CA]; WANG JUAN [US]; KANE ANIL [CA]; CHOW KWOK [CA]; LAMBING JOE [US]


Application No.: US20130177648A1  Published: 11/Jul/2013

Title: COLLAGEN/HYDROXYAPATITE COMPOSITE SCAFFOLD, AND PROCESS FOR THE PRODUCTION THEREOF

Applicant/Assignee: ROYAL COLLEGE OF SURGEONS IN IRELAND

Application No.: 13/786891   Filing Date: 06/Mar/2013

Abstract:

A process for producing a collagen/hydroxyapatite (HA) composite scaffold comprises the steps of forming a homogenous suspension of collagen and HA in an acidic solution, lyophilising the suspension until a desired final freezing temperature is reached to produce the composite scaffold, and optionally cross-linking the composite scaffold, wherein the ratio of HA to collagen is at least 1:10 (w/w). Also provided is a collagen/hydroxyapatite (HA) composite scaffold comprising a homogenous distribution of hydroxyapatite within a porous, crosslinked, collagen matrix, wherein the ratio of HA to collagen is at least 1:10 (w/w). Suitably, the composite scaffold has a porosity of at least 99% (v/v), and a compressive stiffness of at least 0.3 KPa. Composite scaffolds of the invention may be used to provide osteoconductive bone implants and tissue engineering implants.

Priority: EP20070394001 Applic. Date: 2007-02-09; US2010-526353 Applic. Date: 2010-02-04

Inventor: O'BRIEN FERGAL JOSEPH [IE]; GLEESON JOHN PATRICK [IE]; PLUNKETT NIAMH [IE]


Application No.: US20130183256A1  Published: 18/Jul/2013

Title: SILICONE SCAR TREATMENT PREPARATION

Applicant/Assignee: ADVANCED BIO-TECHNOLOGIES, INC

Application No.: 13/548899   Filing Date: 13/Jul/2012

Abstract:

Disclosed is 1) a method for greatly increasing the solubility of useful actives in siloxane matrix-forming preparations, and 2) the associated preparations, themselves. Volatilizing coagents are utilized to give novel gels containing heretofore siloxane-insoluble additives.

Priority: US2009-487489 Applic. Date: 2009-06-18

Inventor: GUILBAUD PAUL [US]


Application No.: US20130184242A1  Published: 18/Jul/2013

Title: Pharmaceutical Composition for Topical Application

Applicant/Assignee: FOAMIX LTD

Application No.: 13/783891   Filing Date: 04/Mar/2013

Abstract:

A pharmaceutical or cosmetic carrier or composition for topical application characterized by rheological properties which render the carrier or composition semi-solid at rest and a liquid upon application of shear forces thereto. The composition or carrier are prepared by mixing 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent, by weight, wherein at least one of them has therapeutic or cosmetic benefits, in the presence or absence of a biologically active substance.

Priority: US2010-705219 Applic. Date: 2010-02-12; US2005-294318 Applic. Date: 2005-12-05; US2003-392071 Applic. Date: 2003-03-19; US2000-653267 Applic. Date: 2000-08-31; US2000-216162P Applic. Date: 2000-07-03

Inventor: EINI MEIR [IL]; TAMARKIN DOV [IL]


Application No.: US20130189338A1  Published: 25/Jul/2013

Title: BONE FIBERS HAVING EXTENDED LENGTH

Applicant/Assignee: WARSAW ORTHOPEDIC, INC

Application No.: 13/353393   Filing Date: 19/Jan/2012

Abstract:

Demineralized bone matrix fibers and demineralized bone compositions are provided. Implantable demineralized bone matrix compositions include elongated bone fibers having an average length from about 2 cm to about 6 cm and an aspect ratio from about 50:1 to about 1000:1. The demineralized bone matrix compositions also include a carrier in an amount sufficient to produce a cohesive formable mass. The elongated fibers can easily entangle to provide an improved demineralized bone matrix having increased osteoconductivity.

Priority:

Inventor: DRAPEAU SUSAN J [US]; WEI GUOBAO [US]


Application No.: US20130195769A1  Published: 01/Aug/2013

Title: OLEAGINOUS PHARMACEUTICAL AND COSMETIC FOAM

Applicant/Assignee: FOAMIX LTD

Application No.: 13/793617   Filing Date: 11/Mar/2013

Abstract:

The invention relates to stable oleaginous cosmetic or therapeutic foam compositions containing certain active agents, having unique therapeutic properties and methods of treatment using such compositions. The foamable composition includes at least one solvent selected from a hydrophobic solvent, a silicone oil, an emollient, a co-solvent, and mixtures thereof, wherein the solvent is present at a concentration of about 70% to about 96.5% by weight of the total composition, at least a non-ionic surface-active agent at a concentration of about 0.1% to less than about 10% by weight of the total composition

at least one gelling agent at a concentration of about 0.1% to about 5% by weight of the total composition

a therapeutically effective amount of at least one active agent

and at least one liquefied or compressed gas propellant, at a concentration of about 3% to about 25% by weight of the total composition.

Priority: US2010-881856 Applic. Date: 2010-09-14; US2004-835505 Applic. Date: 2004-04-28; US2003-530015P Applic. Date: 2003-12-16; US2003-492385P Applic. Date: 2003-08-04

Inventor: TAMARKIN DOV [IL]; FRIEDMAN DORON [IL]; EINI MEIR [IL]; BESONOV ALEX [IL]


Application No.: US20130195773A1  Published: 01/Aug/2013

Title: COMPOSITIONS

Applicant/Assignee: SYMRISE AG

Application No.: 13/728219   Filing Date: 27/Dec/2012

Abstract:

Compositions, comprising menthofuran and selected menthol compounds which feature improved flavour and odour properties, are provided and, in addition, the production of compositions, specifically, of emulsions with an improved storage stability.

Priority: EP20120153019 Applic. Date: 2012-01-30

Inventor: KINDEL GUENTER [DE]; KRAMMER GERHARD [DE]; SIEGEL SVEN [DE]


Application No.: US20130196854A1  Published: 01/Aug/2013

Title: METHOD FOR PRODUCING AN AGRICULTURAL PRODUCT

Applicant/Assignee: KAO CORPORATION

Application No.: 13/820352   Filing Date: 01/Sep/2011

Abstract:

The present invention provides the efficacy-enhancing agent composition for an agricultural chemical containing at least one compound (A) selected from specific ethoxylate compounds, specific polyoxyethylene fatty acid esters, specific polyoxyethylene sorbitan fatty acid esters, specific (poly)glycerol fatty acid esters, and specific alkyl saccharides

and at least one compound (B) selected from specific polyoxyalkylene alkyl ethers and specific aliphatic alcohols.

Priority: JP20100197725 Applic. Date: 2010-09-03; JP20110047410 Applic. Date: 2011-03-04; JP20110047411 Applic. Date: 2011-03-04; WO2011JP69863 Applic. Date: 2011-09-01

Inventor: KAMEI MASATOSHI [JP]; MIZUSHIMA HIROMOTO [JP]


Application No.: US20130197035A1  Published: 01/Aug/2013

Title: Surgical Adjuvant Composition and Associated Methods of Use

Applicant/Assignee:

Application No.: 13/795689   Filing Date: 12/Mar/2013

Abstract:

Disclosed herein are surgical adjuvant compositions for ameliorating tissue and cellular necrosis and/or apoptosis. In addition, surgical methods are described which include the use of the adjuvant of the composition to reduce tissue and cellular necrosis and/or apoptosis.

Priority: US2010-791046 Applic. Date: 2010-06-01

Inventor: LO IAN K Y [CA]; SCIORE PAUL [CA]; MULDREW KEN [CA]


Application No.: US20130197468A1  Published: 01/Aug/2013

Title: Device for Intramyocardial Delivery

Applicant/Assignee: CARNEGIE MELLON UNIVERSITY, UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

Application No.: 13/751414   Filing Date: 28/Jan/2013

Abstract:

Methods and apparatuses for delivery of biologically active material and/or sensors to a target organ or system. The apparatuses allow for specific, controlled delivery of the biologically active material and targeted placement of sensors. The apparatuses may be fabricated from cellular and/or acellular biological active components to promote integration of sensors into tissue and achieve appropriate release of biologically active molecules. The apparatuses may be fabricated from plasma-containing materials or other biopolymers such that the apparatus will resorbed into the tissue following insertion. The biologically active cellular or acellular component may be incorporated into that material may then serve as the source of the therapeutic biologically active component. The apparatus may take the form of a screw, though numerous shapes arc contemplated. The delivery methods and apparatuses of the present invention may be employed in a wide variety of physiological and medical situations, with cardiac implementations being particularly appropriate.

Priority: US201261590938P Applic. Date: 2012-01-26

Inventor: SCHWARTZMAN DAVID [US]; WEISS LEE E [US]; CAMPBELL PHIL GORDON [US]; FEDDER GARY K [US]


Application No.: US20130202704A1  Published: 08/Aug/2013

Title: USE OF MEXIPROSTIL IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE AND/OR OF IRRITABLE BOWEL SYNDROME

Applicant/Assignee: COSMO TECHNOLOGIES LTD

Application No.: 13/880125   Filing Date: 18/Oct/2011

Abstract:

The invention relates to the use of mexiprostil in the treatment and/or prevention of inflammatory bowel disease and of irritable bowel syndrome, to the combinations of mexiprostil with other drugs, and also to a novel method for the synthesis of mexiprostil.

Priority: IT2010MI01908 Applic. Date: 2010-10-19; WO2011IB54627 Applic. Date: 2011-10-18

Inventor: ASSANDRI ALESSANDRO [CH]; MORO LUIGI [IT]


Application No.: US20130203862A1  Published: 08/Aug/2013

Title: SOLUTIONS OF CARBON NANOHORNS, METHOD FOR MAIKING SAME AND USES THEREOF

Applicant/Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS

Application No.: 13/702817   Filing Date: 07/Jun/2011

Abstract:

Methods for solubilizing carbon nanohorns and applications thereof, including the manufacture of composites, hydrogen storage, catalyst supports and drug delivery. In certain embodiments, the method can include: a) Reduction of pristine carbon nanohorns by an alkali metal to lead to a carbon nanohorn alkali salt

and b) Exposure of said carbon nanohorn alkali salt to a polar aprotic solvent to lead to a solution of reduced carbon nanohorns. In certain other embodiments, solutions of carbon nanohorns, and individual carbon nanohorns are obtainable by the methods, as well as uses of such individual carbon nanohorns and solutions of carbon nanohorns.

Priority: EP20100165108 Applic. Date: 2010-06-07; WO2011IB52472 Applic. Date: 2011-06-07

Inventor: PENICAUD ALAIN [FR]; VOIRY DAMIEN [FR]; TAGMATARCHIS NIKOS [GR]; PAGONA GEORGIA [GR]


Application No.: US20130203863A1  Published: 08/Aug/2013

Title: METHOD FOR PREPARING A COMPOSITION INCLUDING A COMPOUND CONTAINING VANILLIN AND ETHYLVANILLIN, COMPOSITION THUS OBTAINED AND USE THEREOF

Applicant/Assignee: RHODIA OPERATIONS

Application No.: 13/581276   Filing Date: 21/Feb/2011

Abstract:

A method for preparing a composition including a compound including vanillin and ethylvanillin is described. Also described, is a method of preparing a composition including a compound including vanillin and ethylvanillin according to a vanillin/ethylvanillin molar ratio of 2. The method can include an operation of co-granulating vanillin and ethylvanillin at a temperature of 50 DEG C. to 57 DEG C. in the form of a powder and in amounts such that the vanillin/ethylvanillin molar ratio is at least equal to 2, and an operation of lowering the temperature of the composition thus obtained to room temperature.

Priority: FR20100000747 Applic. Date: 2010-02-24; WO2011EP52534 Applic. Date: 2011-02-21

Inventor: LE-THIESSE JEAN-CLAUDE [FR]; LAMIRI KILANI [FR]


Application No.: US20130210729A1  Published: 15/Aug/2013

Title: NON-AQUEOUS OILY INJECTABLE FORMULATION EXHIBITING PRESERVATIVE EFFICACY

Applicant/Assignee: LG LIFE SCIENCES, LTD

Application No.: 13/820698   Filing Date: 09/Sep/2011

Abstract:

Disclosed herein is preferably a multi-dose type non-aqueous oily injectable formulation including

an active ingredient (drug) expressing therapeutic effects, which is dissolved, dispersed or suspended in a therapeutically effective amount, in oil. The disclosed non-aqueous oily injectable formulation may include

an oil-affinitive preservative, and a hydrophilic excipient non-phase separable from the oil-affinitive preservative when the excipient is mixed with the oil-affinitive preservative.

Priority: KR20100091036 Applic. Date: 2010-09-16; WO2011KR06707 Applic. Date: 2011-09-09

Inventor: SO JIN EON [KR]; YEO DONG JUN [KR]; JANG YOON-SEON [KR]


Application No.: US20130210930A1  Published: 15/Aug/2013

Title: ORGANOPOLYSILOXANE AND USE THEREOF AS SURFACTANT, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL-BASED RAW MATERIAL OR GELLING AGENT. GEL AND EMULSION COMPOSITIONS, AS WELL AS, PREPARATIONS FOR EXTERNAL USE AND COSMETICS COMPRISING THE SAME

Applicant/Assignee: DOW CORNING TORAY CO., LTD

Application No.: 13/643666   Filing Date: 28/Apr/2011

Abstract:

The present invention provides a co-modified organopolysiloxane having a specified chemical structure in which a sugar alcohol-modified group and a silylalkyl group having a siloxane dendron structure, and optionally a long-chain hydrocarbon group are present. The co-modified organopolysiloxane is blended, as a surfactant, a powder treatment agent, a gelling agent or the like, or as a cosmetic raw material together with powder (s), oil agent (s) or the like, in a preparation for external use, and in particular, a cosmetic.

Priority: JP20100105896 Applic. Date: 2010-04-30; WO2011JP60799 Applic. Date: 2011-04-28

Inventor: SOUDA TATSUO [JP]; TAMURA SEIKI [JP]; IMURA TOMOHIRO [JP]; HAYASHI AKITO [JP]; SAWAYAMA SAYURI [JP]; FURUKAWA HARUHIKO [JP]


Application No.: US20130213398A1  Published: 22/Aug/2013

Title: DRY POWDER FORMULATIONS AND METHODS FOR TREATING PULMONARY DISEASES

Applicant/Assignee:

Application No.: 13/817963   Filing Date: 26/Aug/2011

Abstract:

The present invention is directed toward respirable dry particles for delivery of divalent metal cation salts and/or monovalent cation salts to the respiratory tract and methods for treating a subject having a respiratory disease and/or infection.

Priority: CA20102713560 Applic. Date: 2010-08-23; WO2011US49435 Applic. Date: 2011-08-26

Inventor: LIPP MICHAEL M [US]; SUNG JEAN C [US]; CLARKE ROBERT W [US]; HAVA DAVID L [US]


Application No.: US20130216611A1  Published: 22/Aug/2013

Title: THERAPEUTIC AGENT FOR FIBROID LUNG

Applicant/Assignee: NITTO DENKO CORPORATION

Application No.: 13/867346   Filing Date: 22/Apr/2013

Abstract:

Disclosed are: a substance transfer carrier to an extracellular matrix-producing cell in the lung, which comprises a retinoid

a therapeutic agent for fibroid lung, which utilized the carrier

and a preparation kit of the therapeutic agent.

Priority: JP20080068227 Applic. Date: 2008-03-17; US201213585736 Applic. Date: 2012-08-14; US2010-933075 Applic. Date: 2010-12-10; WO2009JP01148 Applic. Date: 2009-03-16

Inventor: NIITSU YOSHIRO [JP]; TAKIMOTO RISHU [JP]


Application No.: US20130216616A1  Published: 22/Aug/2013

Title: CUSTOMIZED POLYPILLS HAVING HIGH DRUG LOADS

Applicant/Assignee: TAILORPILL TECHNOLOGIES, LLC

Application No.: 13/842414   Filing Date: 15/Mar/2013

Abstract:

Patient-specific polypills, or similar drug products with potential to benefit from reduced need for bulking agent and preferably having multiple active ingredients, producible via appropriately adapted "micro-dosing" technologies not requiring fluid-jet or like substrate and solvent dependent approaches, having less need for excipient, particularly filler, so that the products may contain a larger number of different drug substances having a lower overall number or amount of excipient materials and/or may contain drug substances having comparatively less need for formulation development or pre-production processing and/or may contain fewer potential causes of side effects.

Priority: US201313757828 Applic. Date: 2013-02-03; WO2011US62167 Applic. Date: 2011-11-26; US201061426576P Applic. Date: 2010-12-23

Inventor: ALFANO KENNETH MIMNAUGH [US]


Application No.: US20130216620A1  Published: 22/Aug/2013

Title: EXTENDED-RELEASE FORMULATION FOR REDUCING THE FREQUENCY OF URINATION AND METHOD OF USE THEREOF

Applicant/Assignee: WELLESLEY PHARMACEUTICALS, LLC

Application No.: 13/847927   Filing Date: 20/Mar/2013

Abstract:

Methods and compositions for reducing the frequency of urination are disclosed. One method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising an analgesic agent formulated in an extended-release formulation. Another method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising multiple active ingredients formulated for extended-release. Yet another method comprises administering to a subject in need thereof an effective amount of a diuretic followed with another administration of a pharmaceutical composition comprising an analgesic agent formulated for extended-release.

Priority: US201213560607 Applic. Date: 2012-07-27; US201213487348 Applic. Date: 2012-06-04; US201213424000 Applic. Date: 2012-03-19; US201213343332 Applic. Date: 2012-01-04; US2010-956634 Applic. Date: 2010-11-30

Inventor: DILL DAVID A [US]


Application No.: US20130216623A1  Published: 22/Aug/2013

Title: APPARATUS AND FORMULATIONS FOR SUPRACHORIDAL DRUG DELIVERY

Applicant/Assignee: ISCIENCE INTERVENTIONAL CORPORATION

Application No.: 13/842218   Filing Date: 15/Mar/2013

Abstract:

Drug formulations, devices and methods are provided to deliver biologically active substances to the eye. The formulations are delivered into scleral tissues adjacent to or into the suprachoroidal space without damage to the underlying choroid. One class of formulations is provided wherein the formulation is localized in the suprachoroidal space near the region into which it is administered. Another class of formulations is provided wherein the formulation can migrate to another region of the suprachoroidal space, thus allowing an injection in the anterior region of the eye in order to treat the posterior region.

Priority: US2007-709941 Applic. Date: 2007-02-21; US2006-776903P Applic. Date: 2006-02-22

Inventor: YAMAMOTO RONALD [US]; CONSTON STANLEY R [US]; SIERRA DAVID [US]


Application No.: US20130217785A1  Published: 22/Aug/2013

Title: COMPOSITE ANIMAL FEED COMPACT

Applicant/Assignee: ENGINUITY WORLDWIDE, LLC

Application No.: 13/841636   Filing Date: 15/Mar/2013

Abstract:

An animal feed compact is provided by the present disclosure that includes a body having a various feed composition and an adhesive additive. The adhesive additive includes a starch and a hydroxide. Further additives may also be provided, which include any edible/digestible alfalfa meal, sunflower meal grain, ruffage [roughage], soybean meal wheat mids, hay, stover, whey dicalcium phosphate, limestone molasses, minerals, vitamins and medication. Various geometries and compositions for the biomass fuel compact are also provided by the present disclosure.

Priority: US201113018211 Applic. Date: 2011-01-31

Inventor: HEIMANN ROBERT L [US]


Application No.: US20130217787A1  Published: 22/Aug/2013

Title: Mixed Ethers and Uses Thereof

Applicant/Assignee: BASF SE

Application No.: 13/768243   Filing Date: 15/Feb/2013

Abstract:

Described herein are mixed ethers and cosmetic and/or pharmaceutical preparations comprising mixed ethers. Certain mixed ethers have a melting range between -25 DEG C. and +70 DEG C., wherein the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35+-10 DEG C. These mixed ethers are obtainable for example by condensation reaction of a) 25 to 90% by weight of unbranched fatty alcohols with a chain length of 12 to 18 carbon atoms

b) 5 to 50% by weight of isostearyl alcohol

c) 0 to 35% by weight of a fatty alcohol with a chain length of 20 and/or 22 carbon atoms

and d) 0 to 25% by weight of a fatty alcohol having 8 and/or 10 carbon atoms.

Priority: US201261599966P Applic. Date: 2012-02-17

Inventor: DIERKER MARKUS [DE]; KEMPERS PETER [DE]; KAWA ROLF [DE]; BRUENING STEFAN [DE]; MILARDOVIC JADRANKA [DE]; BECKEDAHL BURKHARD [DE]; MAHNKE EIKE ULF [DE]; KRUEPPEL HEINZ-JOSEF [DE]


Application No.: US20130217788A1  Published: 22/Aug/2013

Title: Guerbet Alcohol Mixtures and Uses Thereof

Applicant/Assignee: BASF SE

Application No.: 13/768264   Filing Date: 15/Feb/2013

Abstract:

Mixtures of Guerbet alcohols, their use in cosmetic and/or pharmaceutical preparations, and also cosmetic and/or pharmaceutical preparations comprising mixtures of Guerbet alcohols are described. Of suitability as petroleum jelly substitute are in particular Guerbet alcohol mixtures with a melting range, measured by differential scanning calorimetry (DSC), between -20 DEG C. and +70 DEG C., where the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35+-10 DEG C. These are obtainable for example by reacting a) 55 to 95% by weight of cetylstearyl alcohol, b) 5 to 45% by weight of fatty alcohols with a chain length of from 8 to 22 carbon atoms and c) optionally an aliphatic diol having at least 3 carbon atoms.

Priority: US201261599965P Applic. Date: 2012-02-17

Inventor: KEMPERS PETER [DE]; KAWA ROLF [DE]; BRUENING STEFAN [DE]; MILARDOVIC JADRANKA [DE]; MAHNKE EIKE ULF [DE]; KRUEPPEL HEINZ-JOSEF [DE]; DIERKER MARKUS [DE]; BECKEDAHL BURKHARD [DE]


Application No.: US20130217789A1  Published: 22/Aug/2013

Title: BIODEGRADABLE LIQUOGEL AND PH SENSITIVE NANOCARRIERS

Applicant/Assignee: NORTH CAROLINA CENTRAL UNIVERSITY

Application No.: 13/818782   Filing Date: 02/Sep/2011

Abstract:

A delivery system using materials that form a liquogel or nanocarrier are described. The delivery system comprises hyperbranched polyglycerols (HPGs). The delivery system can include a drug or therapeutic agent and this system can be used to administer the drug or therapeutic agent locally. The delivery system provides for controlled release of the drug or therapeutic agent.

Priority: US2010-380076P Applic. Date: 2010-09-03; WO2011US50405 Applic. Date: 2011-09-02

Inventor: TAYLOR DARLENE K [US]; OCHIENG MELONY A [US]


Application No.: US20130224261A1  Published: 29/Aug/2013

Title: ENVIRONMENTALLY-RESPONSIVE NANOCOMPOSITES AND METHODS OF THEIR USE

Applicant/Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION, THROUGH ITS CENTER FOR COMMERCIALIZATION UNIVERSITY OF WASHINGTON

Application No.: 13/770943   Filing Date: 19/Feb/2013

Abstract:

Environmentally-responsive composites useful for intracellular delivery of therapeutic agents.

Priority: WO2011US48497 Applic. Date: 2011-08-19; US2010-375229P Applic. Date: 2010-08-19

Inventor: SHEN HONG [US]


Application No.: US20130224292A1  Published: 29/Aug/2013

Title: ACAMPROSATE FORMULATIONS, METHODS OF USING THE SAME, AND COMBINATIONS COMPRISING THE SAME

Applicant/Assignee: SYNCHRONEURON INC

Application No.: 13/853876   Filing Date: 29/Mar/2013

Abstract:

Embodiments disclosed herein generally relate to acamprosate formulations, methods of use of the formulations, to methods of using the formulations in combination with at least one other medication, and to combination products and compositions comprising the formulations and at least one other medication, such as neuroleptic (antipsychotic) and/or antidepressant drugs.

Priority: US201313745619 Applic. Date: 2013-01-18; WO2012US67507 Applic. Date: 2012-12-02; US201261649137P Applic. Date: 2012-05-18; US201161566550P Applic. Date: 2011-12-02

Inventor: FOGEL BARRY S [US]; KERNS WILLIAM D [US]; FONG KEI-LAI [US]


Application No.: US20130224300A1  Published: 29/Aug/2013

Title: COMPOSITIONS AND METHODS THEREOF FOR ORAL ADMINISTRATION OF DRUGS

Applicant/Assignee:

Application No.: 13/594478   Filing Date: 24/Aug/2012

Abstract:

The present invention provides therapeutic compositions including a therapeutic agent in a non-aqueous matrix having an absorption enhancer and therapeutic agent, as well as methods for administering such compositions and providing enhanced oral bioavailability.

Priority: US201161527788P Applic. Date: 2011-08-26

Inventor: MAGGIO EDWARD T [US]


Application No.: US20130230473A1  Published: 05/Sep/2013

Title: USE OF SUBSTITUTED METHOXYALKOXYPHENYLALKYL DERIVATIVES AS PRESERVATIVE, PRESERVING METHOD, COMPOUNDS AND COMPOSITION

Applicant/Assignee: L'OREAL

Application No.: 13/824172   Filing Date: 06/Oct/2011

Abstract:

The present invention relates to the use as a preserving agent, in particular in cosmetic or dermatological composition, of at least one compound of formula (I): in which:-X represents =O or -OH

-R1 represents a hydrogen atom or a methyl

-R2 represents a hydrogen atom, a methyl or an ethyl

-R3 represents a C1-C12, saturated or unsaturated, linear hydrocarbon-based radical, optionally substituted with a hydroxyl group (OH)

with the exclusion of the compound of formula (I) in which X represents =O, R1=methyl, R2=H and R3=-(CH2)6-CH3. The invention also relates to certain novel compounds and to the cosmetic or dermatological compositions comprising same.

Priority: FR20100058182 Applic. Date: 2010-10-08; US2010-392082P Applic. Date: 2010-10-12; WO2011EP67450 Applic. Date: 2011-10-06

Inventor: DALKO MARIA [FR]; GILBERT LAURENT [FR]


Application No.: US20130230476A1  Published: 05/Sep/2013

Title: Fragrance Compositions Comprising Special Mixtures of Diastereomers of 2-Isobutyl-4-Methyl-Tetrahydro-2H-Pyran-4-OL

Applicant/Assignee: BASF SE

Application No.: 13/884503   Filing Date: 08/Nov/2011

Abstract:

The present invention relates to a fragrance composition comprising a mixture of diastereomers of 2-isobutyl-4-methyl-tetrahydro-2H-pyran-4-ol, which comprises more than 95 wt. % of the optically inactive cis-racemate and less than 5 wt. % of the optically inactive trans-racemate. The present invention further relates to a method for producing a perfumed product or article as well as perfumed or aromatized articles comprising the fragrance compositions of the present invention.

Priority: EP20100190693 Applic. Date: 2010-11-10; US2010-411944P Applic. Date: 2010-11-10; WO2011EP69676 Applic. Date: 2011-11-08

Inventor: PELZER RALF [DE]; KRAUSE WOLFGANG [DE]; BECK KARL [DE]; BOCRIS FRANCIS [FR]


Application No.: US20130231399A9  Published: 05/Sep/2013

Title: AZEOTROPE-LIKE COMPOSITIONS COMPRISING 1-CHLORO-3,3,3-TRIFLUOROPROPENE

Applicant/Assignee: HONEYWELL INTERNATIONAL INC

Application No.: 13/298452   Filing Date: 17/Nov/2011

Abstract:

An azeotrope-like mixture consisting essentially of chlorotrifluoropropene and at least one component selected from the group consisting of a C1-C3 alcohol, a C5-C6 hydrocarbon, a halogenated hydrocarbon, methylal, methyl acetone, water, nitromethane, and combinations thereof.

Priority: US2009-605609 Applic. Date: 2009-10-26; US2008-259694 Applic. Date: 2008-10-28; US2008-276137 Applic. Date: 2008-11-21; US2008-109007P Applic. Date: 2008-10-28

Inventor: BASU RAJAT [US]; BEMENT LESLIE [US]; COOK KANE [US]; HULSE RYAN [US]; KNOPECK GARY [US]; PHAM HANG T [US]; SINGH RAJIV R [US]; WILLIAMS DAVID J [US]


Application No.: US20130236513A1  Published: 12/Sep/2013

Title: Synthetic Polyurethane Composite

Applicant/Assignee: VANDERBILT UNIVERSITY

Application No.: 13/868077   Filing Date: 22/Apr/2013

Abstract:

Embodiments of the present inventions comprise composites of polyurethane(s), osteoconductive matrix, and, optionally, a growth factor. Embodiments further comprise methods of making such composite and uses thereof. The osteoconductive matrix can be a tricalcium phosphate, bioglass, or the like, and can include particles that are surface modified. Growth factors can be provided in powder form, including bone morphogenic proteins such as rhBMP-2. A composition may be moldable and/or injectable. After implantation or injection, a composition may be set to form a porous composite that provides mechanical strength and supports the in-growth of cells.

Priority: WO2011US57551 Applic. Date: 2011-10-24; US2010-406098P Applic. Date: 2010-10-22; US201161433944P Applic. Date: 2011-01-18

Inventor: GUELCHER SCOTT A [US]; DUMAS JERALD [US]; PRIETO EDNA M [US]; KALPAKCI KEREM [US]; TALLEY ANNE [US]; HARMATA ANDREW [US]; ZIENKIEWICZ KATARZYNA [US]


Application No.: US20130237616A1  Published: 12/Sep/2013

Title: MODIFIED ALKOXYLATION PRODUCTS HAVING AT LEAST ONE NON-TERMINAL ALKOXYSILYL GROUP AND A PLURALITY OF URETHANE GROUPS, AND THEIR USE

Applicant/Assignee: EVONIK GOLDSCHMIDT GMBH

Application No.: 13/793356   Filing Date: 11/Mar/2013

Abstract:

Alkoxylation products, their preparation, compositions comprising these alkoxylation products, and the use thereof as or for producing adhesives and sealants.

Priority: DE201210203737 Applic. Date: 2012-03-09

Inventor: FERENZ MICHAEL [DE]; BRUGGER BASTIAN MATTHIAS [DE]; LOBERT MATTHIAS [DE]; ZELLMER VOLKER [DE]; SCHUBERT FRANK [DE]; KNOTT WILFRIED [DE]; ROESSING MELANIE [DE]


Application No.: US20130243695A1  Published: 19/Sep/2013

Title: CHEMOEMBOLISATION

Applicant/Assignee: BIOCOMPATIBLES UK LIMITED

Application No.: 13/873438   Filing Date: 30/Apr/2013

Abstract:

A composition for chemoembolotherapy of solid tumours comprises particles of a water-insoluble water-swellable synthetic anionic polymer and, absorbed therein an anthracycline. Suitably the polymer is a poly(vinyl alcohol) based polymer and the drug is doxorubicin.

Priority: EP20030250868 Applic. Date: 2003-02-12; US201213452337 Applic. Date: 2012-04-20; US2008-210573 Applic. Date: 2008-09-15; US2006-434274 Applic. Date: 2006-05-16; US2003-366603 Applic. Date: 2003-02-14

Inventor: LEWIS ANDREW LENNARD [GB]; STRATFORD PETER WILLIAM [GB]; LEPPARD SIMON [GB]; GARCIA PEDRO [GB]; HALL BRENDA [GB]; GONZALEZ MARIA VICTORIA FAJARDO [GB]


Application No.: US20130243706A1  Published: 19/Sep/2013

Title: TRANSFER RESISTANT COSMETICS AND METHOD OF MAKING

Applicant/Assignee: COTY INC

Application No.: 13/822568   Filing Date: 08/Nov/2011

Abstract:

Embodiments claimed and claimed herein include anhydrous cosmetic composition embodiments. The anhydrous cosmetic composition embodiments include coconut alkanes comprising a volatile oily composition having from 50 to 100% by weight of a mixture of linear paraffins that include 70 to 99% by weight of at least one linear paraffin selected from C %, C10, C12 paraffins and mixtures thereof. The composition also includes a coconut gel comprising vegetable oil, Cocos Nucifera Oil, a styrene/butadiene copolymer and polyethylene. The composition embodiments also include polyethylene, caprylyl glycol, and a mixture of Acacia Decurrens/Jojoba/Sunflower Seed wax/Polyglyceryl 3-ester in concentrations effective for ensuring coconut alkanes are melted and homogeneous

and one or more anhydrous actives.

Priority: US2010-411172P Applic. Date: 2010-11-08; WO2011US59744 Applic. Date: 2011-11-08

Inventor: BARONE SALVATORE J [US]; NGUYEN LETHU [US]; MAILLARD FREDERICKE VANCE [FR]


Application No.: US20130243716A1  Published: 19/Sep/2013

Title: DIHYDROBENZOFURAN DERIVATIVES AS FRAGRANCE AND/OR FLAVORING MATERIALS

Applicant/Assignee: SYMRISE AG

Application No.: 13/838855   Filing Date: 15/Mar/2013

Abstract:

Compounds and methods of using of compounds or mixtures thereof, as fragrance and/or flavoring material or as fragrance and/or flavoring material mixture, new fragrance and/or flavoring material mixtures, new perfumed and/or flavored articles, and new, particularly advantageous compounds and mixtures to be used are described.

Priority: EP20120160062 Applic. Date: 2012-03-19

Inventor: OERTLING HEIKO [CH]; GOEMANN CLAUDIA [DE]; VOM ENDE MARC [DE]


Application No.: US20130244880A1  Published: 19/Sep/2013

Title: Novel pesticide formulations

Applicant/Assignee: HICAP FORMULATIONS LTD2

Application No.: 13/385916   Filing Date: 14/Mar/2012

Abstract:

Bioactive substances are imbedded or mixed into functionalized matrices to form homogenous water-insoluble solid complexes with desirable field properties such as reduced leaching in soil, improved leaf retention (rainfastness), selective unloading to roots and convenient packaging and application. Bioactive substances that may be so complexed include pharmaceutical agents and pesticides including herbicides, insecticides, bacteriocides, rodenticides, nematicide and fungicides. The matrices comprise either a monomeric-, oligomeric- or (co)polymeric backbone which may be derivatized with chemical groups that exhibit ionic (amines, carboxyls), hydrophobic, and ligand-binding interactions to form the matrix of the formulation. The various matrices may be mixed with additives or modifiers, grafted, or fused to obtain optimal properties. The matrix/pesticide formulations may be applied as granules, as suspensions, emulsions in sprays, as foams, or as coats for seeds and fertilizers. Alternatively they may be melted and sprayed as concentrates. The formulations may be applied to foliage, soil, irrigation water, construction materials, seeding materials, grains, and buildings.

Priority:

Inventor: BURNET MICHAEL WILLIAM [DE]; GUSE JAN-HINRICH [DE]; REISSER MARTIN [DE]


Application No.: US20130245131A1  Published: 19/Sep/2013

Title: Hydrogenation of Mixed Oxygenate Stream to Produce Alcohol

Applicant/Assignee: CELANESE INTERNATIONAL CORPORATION

Application No.: 13/419588   Filing Date: 14/Mar/2012

Abstract:

The present invention relates to processes for the recovery of ethanol from a crude ethanol product obtained from the hydrogenation of a mixed oxygenate stream comprising ethyl acetate and acetaldehyde. The crude ethanol product is separated in at least one distillation column to product ethanol. The mixed oxygenate stream may be obtained from syngas.

Priority:

Inventor: ZHOU ZHENHUA [US]; JEVTIC RADMILA [US]; JOHNSTON VICTOR J [US]; WEINER HEIKO [US]


Application No.: US20130245132A1  Published: 19/Sep/2013

Title: PROCESS FOR PREPARING 4-CYCLOHEXYL-2-METHYL-2-BUTANOL

Applicant/Assignee: BASF SE

Application No.: 13/873343   Filing Date: 30/Apr/2013

Abstract:

Process for preparing 4-cyclohexyl-2-methyl-2-butanol The present invention relates to a process for preparing 4-cyclohexyl-2-methyl-2-butanol. The process comprises the following steps: a) reaction of styrene with isopropanol at elevated temperature to obtain 4-phenyl-2-methyl-2-butanol, and b) heterogeneously catalyzed hydrogenation of 4-phenyl-2-methyl-2-butanol over a catalyst suitable for ring hydrogenation of aromatics.

Priority: US201113071002 Applic. Date: 2011-03-24; US2010-316870P Applic. Date: 2010-03-24

Inventor: EBEL KLAUS [DE]; RUEDENAUER STEFAN [DE]; PELZER RALF [DE]; BOCK MARTIN [DE]


Application No.: US20130251644A1  Published: 26/Sep/2013

Title: Cyclodextrin-Based Microemulsions, and Dermatological Uses Thereof

Applicant/Assignee: PRECISION DERMATOLOGY, INC

Application No.: 13/803433   Filing Date: 14/Mar/2013

Abstract:

Described herein are cyclodextrin-stabilized microemulsion systems useful for increasing the solubility, stability, bioavailability, or safety of an active agent for delivery to the skin. The microemulsions may reduce the occurrence of skin irritation or odor upon application. In certain embodiments, the active agent is substantially insoluble in water. The microemulsions may be formulated as semi-solids, for example creams, or as aerosol or non-aerosol foams. Also described are methods of treating skin disorders, comprising the step of applying to an affected area of a subject in need thereof a therapeutically-effective amount of an inventive microemulsion.

Priority: US201261614177P Applic. Date: 2012-03-22

Inventor: MAJHI PINAKI RANJAN [US]; TRUMBORE MARK W [US]


Application No.: US20130251789A1  Published: 26/Sep/2013

Title: TAMPER-RESISTANT ORAL OPIOID AGONIST FORMULATIONS

Applicant/Assignee: PURDUE PHARMA L.P

Application No.: 13/718879   Filing Date: 18/Dec/2012

Abstract:

Disclosed is an oral dosage form comprising: (i) an opioid agonist in releasable form and (ii) a sequestered opioid antagonist which is not released when the dosage form is administered orally intact.

Priority: US201213544333 Applic. Date: 2012-07-09; US2010-909614 Applic. Date: 2010-10-21; US2003-689866 Applic. Date: 2003-10-21; US2001-781081 Applic. Date: 2001-02-08; US2000-181369P Applic. Date: 2000-02-08

Inventor: OSHLACK BENJAMIN [AU]; WRIGHT CURTIS [US]; HADDOX J DAVID [US]


Application No.: US20130251796A1  Published: 26/Sep/2013

Title: TAMPER RESISTANT DOSAGE FORMS

Applicant/Assignee: PURDUE PHARMA L.P

Application No.: 13/901027   Filing Date: 23/May/2013

Abstract:

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

Priority: US2007-844872 Applic. Date: 2007-08-24; US2006-840244P Applic. Date: 2006-08-25

Inventor: MCKENNA WILLIAM H [US]; MANNION RICHARD O [US]; O'DONNELL EDWARD P [US]; HUANG HAIYONG H [US]


Application No.: US20130251797A1  Published: 26/Sep/2013

Title: TAMPER RESISTANT DOSAGE FORMS

Applicant/Assignee: PURDUE PHARMA L.P

Application No.: 13/901174   Filing Date: 23/May/2013

Abstract:

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

Priority: US2007-844872 Applic. Date: 2007-08-24; US2006-840244P Applic. Date: 2006-08-25

Inventor: MCKENNA WILLIAM H [US]; MANNION RICHARD O [US]; O'DONNELL EDWARD P [US]; HUANG HAIYONG H [US]


Application No.: US20130251800A1  Published: 26/Sep/2013

Title: TAMPER RESISTANT DOSAGE FORMS

Applicant/Assignee: PURDUE PHARMA L.P

Application No.: 13/901142   Filing Date: 23/May/2013

Abstract:

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

Priority: US2007-844872 Applic. Date: 2007-08-24; US2006-840244P Applic. Date: 2006-08-25

Inventor: MCKENNA WILLIAM H [US]; MANNION RICHARD O [US]; O'DONNELL EDWARD P [US]; HUANG HAIYONG H [US]


Application No.: US20130251818A1  Published: 26/Sep/2013

Title: PERSONAL LUBRICANTS

Applicant/Assignee: NATURE LABS USA LLC

Application No.: 13/849000   Filing Date: 22/Mar/2013

Abstract:

Personal lubricants containing royal jelly, a glow powder or xylitol are provided.

Priority: US201261614139P Applic. Date: 2012-03-22

Inventor: RIVERS IV LOUIS J [US]; STRANEN KEVIN [US]


Application No.: US20130253014A1  Published: 26/Sep/2013

Title: Cyclodextrin-Based Microemulsions, and Dermatological Uses Thereof

Applicant/Assignee: PRECISION DERMATOLOGY, INC

Application No.: 13/803280   Filing Date: 14/Mar/2013

Abstract:

Described herein are cyclodextrin-stabilized microemulsion systems useful for increasing the solubility, stability, bioavailability, or safety of an active agent for delivery to the skin. The microemulsions may reduce the occurrence of skin irritation or odor upon application.

Priority: US201261614177P Applic. Date: 2012-03-22

Inventor: TRUMBORE MARK W [US]; MAJHI PINAKI RANJAN [US]; SHAH DINEN DIVYANG [US]


Application No.: US20130253015A1  Published: 26/Sep/2013

Title: Cyclodextrin-Based Microemulsions, and Dermatological Uses Thereof

Applicant/Assignee: PRECISION DERMATOLOGY, INC

Application No.: 13/803407   Filing Date: 14/Mar/2013

Abstract:

Described herein are cyclodextrin-stabilized microemulsion systems useful for increasing the solubility, stability, bioavailability, or safety of an active agent for delivery to the skin. The microemulsions may reduce the occurrence of skin irritation or odor upon application. In certain embodiments, the active agent is substantially insoluble in water.

Priority: US201261614177P Applic. Date: 2012-03-22

Inventor: MAJHI PINAKI RANJAN [US]; TRUMBORE MARK W [US]


Application No.: US20130255061A1  Published: 03/Oct/2013

Title: SYSTEMS AND METHODS FOR APPLYING A NOVEL ANTIMICROBIAL COATING MATERIAL TO A MEDICAL DEVICE

Applicant/Assignee: BECTON, DICKINSON AND COMPANY

Application No.: 13/438559   Filing Date: 03/Apr/2012

Abstract:

An antimicrobial composition, generally comprising a biocidal agent, such as chlorhexidine gluconate, a lubricant, such as a modified siloxane, and a solvent, such as an alcohol and/or water. The biocidal agent acts as a highly effective biocide while the lubricant reduces friction between various components of a medical device during assembly. The antimicrobial composition may be applied to an internal component of the medical device prior to assembly. The process of assembling the medical device results in antimicrobial composition being distributed to various internal structures and geometries of the medical device as the coated, internal component is assembled into the interior of the medical device. Air is then used to further distribute excess antimicrobial agent to the remaining surfaces downstream from the installed, internal component. In some embodiments, additional air is passed through the assembled medical device to assist in removing the carrier solvent from the medical device via evaporation.

Priority:

Inventor: BURKHOLZ JONATHAN KARL [US]; HOANG MINH QUANG [US]


Application No.: US20130259582A1  Published: 03/Oct/2013

Title: SOIL ADHERENT PELLET AND ACTIVE AGENT DELIVERY WITH SAME

Applicant/Assignee: THE ANDERSONS, INC

Application No.: 13/854447   Filing Date: 01/Apr/2013

Abstract:

A soil adherent pellet is detailed that includes a soluble calcium ion source, a magnesium ion source, or both present in an amount ranging from 15% to 99.9% by weight of a total dry weight of the pellet and a binder present in an amount ranging from 85% to 0.1% by weight of the total dry weight of the pellet. The pellet having a mean pellet domain size and a pellet surface. The soil adherent pellet is well suited for flocculating clay within the soil and delivery of an active ingredient with reduced runoff compared to prior art broadcast particles. A soil adherent pellet is also provided having a soluble calcium and/or magnesium ion source that is polycrystalline and carries therewith an active ingredient.

Priority: US201261618783P Applic. Date: 2012-03-31

Inventor: BIRTHISEL TIMOTHY D [US]; SCHALK JOSEPH [US]; SCHANSKI JOSEPH [US]


Application No.: US20130259913A1  Published: 03/Oct/2013

Title: PARTICLES AND PARTICLE GAS SATURATED SOLUTION PROCESSES FOR MAKING SAME

Applicant/Assignee:

Application No.: 13/433336   Filing Date: 29/Mar/2012

Abstract:

Particles containing at least two incompatible materials, such as a hydrophilic agent and a lipophilic agent, and particles from gas saturated solution (PGSS) processes for making such particles are provided.

Priority:

Inventor: RAUCKHORST HOLLY BALASUBRAMANIAN [US]; STELLA QING [US]; DREHER ANDREAS JOSEF [US]


Application No.: US20130259937A1  Published: 03/Oct/2013

Title: AMPHIPATHIC LIPID-BASED SUSTAINED RELEASE COMPOSITIONS

Applicant/Assignee:

Application No.: 13/907180   Filing Date: 31/May/2013

Abstract:

Chewable sustained release compositions and their methods of production are provided. The sustained release compositions contain amphipathic lipids and matrix-forming polymers, which are used to encapsulate various drugs and active ingredients. The chewable sustained release compositions can maintain their sustained release properties even after being fragmented into a plurality of pieces.

Priority: US201213690974 Applic. Date: 2012-11-30; US201161566279P Applic. Date: 2011-12-02

Inventor: HOWARD SCOTT A [US]; PURVIS TROY [US]


Application No.: US20130261093A1  Published: 03/Oct/2013

Title: COSMETIC COMPOSITION IN THE FORM OF AN OIL-IN-WATER EMULSION

Applicant/Assignee: L'OREAL S.A, L'OREAL

Application No.: 13/434531   Filing Date: 29/Mar/2012

Abstract:

A cosmetic composition in the form of an oil-in-water emulsion methods of using and producing cosmetic compositions is provided. The cosmetic composition includes an aqueous phase, an oil phase comprising a water-in-oil emulsifier, and an oil stabilizing component. The water-in-oil emulsifier is at concentration, by weight, of about 0.01% to about 6.0%, based upon weight of the composition. The oil stabilizing component includes one or both of an amphiphilic compound or a surfactant having an HLB of 13 or greater added to the aqueous phase. The oil stabilizing component is at a concentration, by weight, of about 0.01% to about 1.0%, based upon weight of the composition. The oil-in-water emulsion has an increased water load relative to water-in-oil emulsions without having an increased viscosity.

Priority:

Inventor: BRIEVA PATRICIA [US]; GALDI ANGELIKE [US]; SIMONNET JEAN-THIERRY [US]; POTIN ANTHONY [US]


Application No.: US20130266652A1  Published: 10/Oct/2013

Title: LIQUID PHARMACEUTICAL COMPOSITION FOR THE DELIVERY OF ACTIVE INGREDIENTS

Applicant/Assignee: NOVALIQ GMBH

Application No.: 13/824048   Filing Date: 18/Oct/2011

Abstract:

The invention provides novel pharmaceutical compositions based on semifluorinated alkanes which are useful as carriers for a broad range of active ingredients. Preferred active ingredients include poorly water-soluble and/or hydrolytically sensitive drug substances. The compositions are designed as suspensions and have superior physical properties which make them highly useful as pharmaceutical delivery systems. The compositions may be administered topically into the eye, or injected via the subcutaneous or intramuscular route. The invention further provides kits comprising such compositions.

Priority: EP20100188242 Applic. Date: 2010-10-20; WO2011EP68141 Applic. Date: 2011-10-18

Inventor: THEISINGER BASTIAN [DE]; THEISINGER SONJA [DE]; GUENTHER BERNHARD [DE]


Application No.: US20130267609A1  Published: 10/Oct/2013

Title: NOVEL LIPID DIPEPTIDE AND GEL

Applicant/Assignee: NISSAN CHEMICAL INDUSTRIES, LTD

Application No.: 13/911500   Filing Date: 06/Jun/2013

Abstract:

There is provided a gelator that is capable of forming a gel by an extremely small amount of addition in a wide pH range from acidic to alkaline regions, and a gel having high environmental compatibility, biocompatibility, and biodegradability. A gelator comprising: a lipid peptide of Formula (1) wherein R1 is a C9-23 aliphatic group, R2 is a hydrogen atom or a C1-4 alkyl group optionally having a C1-2 branched chain, R3 is a -(CH2)n-X group, n is a number from 1 to 4, and X is an amino group, a guanidino group, a -CONH2 group, or a 5-membered ring optionally having 1 to 3 nitrogen atoms, a 6-membered ring optionally having 1 to 3 nitrogen atoms, or a fused heterocycle including a 5-membered ring and a 6-membered ring that optionally has 1 to 3 nitrogen atoms)

or a pharmaceutically usable salt of the lipid peptide.

Priority: JP20080200108 Applic. Date: 2008-08-01; US201113056517 Applic. Date: 2011-04-04; WO2009JP61248 Applic. Date: 2009-06-19

Inventor: MIYAMOTO MISAO [JP]; MIYACHI NOBUHIDE [JP]; IWAMA TAKEHISA [JP]


Application No.: US20130267610A1  Published: 10/Oct/2013

Title: NOVEL LIPID DIPEPTIDE AND GEL

Applicant/Assignee: NISSAN CHEMICAL INDUSTRIES, LTD

Application No.: 13/911533   Filing Date: 06/Jun/2013

Abstract:

There is provided a gelator that is capable of forming a gel by an extremely small amount of addition in a wide pH range from acidic to alkaline regions, and a gel having high environmental compatibility, biocompatibility, and biodegradability. A gelator comprising: a lipid peptide of Formula (1) wherein R1 is a C9-23 aliphatic group, R2 is a hydrogen atom or a C1-4 alkyl group optionally having a C1-2 branched chain, R3 is a -(CH2)n-X group, n is a number from 1 to 4, and X is an amino group, a guanidino group, a -CONH2 group, or a 5-membered ring optionally having 1 to 3 nitrogen atoms, a 6-membered ring optionally having 1 to 3 nitrogen atoms, or a fused heterocycle including a 5-membered ring and a 6-membered ring that optionally has 1 to 3 nitrogen atoms)

or a pharmaceutically usable salt of the lipid peptide.

Priority: JP20080200108 Applic. Date: 2008-08-01; US201113056517 Applic. Date: 2011-04-04; WO2009JP61248 Applic. Date: 2009-06-19

Inventor: MIYAMOTO MISAO [JP]; MIYACHI NOBUHIDE [JP]; IWAMA TAKEHISA [JP]


Application No.: US20130273162A1  Published: 17/Oct/2013

Title: Oral Film Containing Opiate Enteric-Release Beads

Applicant/Assignee:

Application No.: 13/445716   Filing Date: 12/Apr/2012

Abstract:

A control release and abuse-resistant opiate drug delivery oral wafer or edible oral film dosage to treat pain and substance abuse is provided. The drug delivery oral wafer or edible oral film dosage includes a controlled release layer containing enteric-release beads dispersed in a polymer matrix. The enteric-release beads are formed from a therapeutic amount of an opioid agonist and/or pharmaceutically acceptable salt thereof and a sub-therapuetic amount of opioid antagonist and/or pharmaceutically acceptable salt thereof coated or encapsulated in an enteric-release polymer. The controlled release polymer matrix dissolves or disintegrates following administration or consumption of the oral wafer or edible oral film, releasing the enteric-release beads to be swallowed, with subsequent absorption of the active ingredients within the patient's intestines.

Priority:

Inventor: LI MICHAEL HSIN CHWEN [US]


Application No.: US20130274339A1  Published: 17/Oct/2013

Title: NOVEL FUNCTIONAL FOOD PRODUCT AND METHOD THEREOF

Applicant/Assignee:

Application No.: 13/864441   Filing Date: 17/Apr/2013

Abstract:

A whole impregnated freeze dried food product for delivering a material of interest comprising

a. moisture content of less than about 5%

b. a material of interest

and, c. taste additives

wherein, the food product is maintained in it's whole original structure, volume and shape

further wherein the food product is functionally impregnated with the material of interest in an amount equivalent to the removed moisture residual, and methods for obtaining same.

Priority: US201261625093P Applic. Date: 2012-04-17

Inventor: LURYA LEONID [IL]; NOVODVORETS VADIM [BY]


Application No.: US20130274352A1  Published: 17/Oct/2013

Title: Oral Drug Devices and Drug Formulations

Applicant/Assignee:

Application No.: 13/802079   Filing Date: 13/Mar/2013

Abstract:

Compositions containing a drug to be delivered and at least one chemical permeation enhancer (CPE), and methods of making and using these compositions are described herein. In a preferred embodiment, the compositions contain two or more CPEs which behave in synergy to increase the permeability of the epithelium, while providing an acceptably low level of cytotoxicity to the cells. The concentration of the one or more CPEs is selected to provide the greatest amount of overall potential (OP). Additionally, the CPEs are selected based on the treatment. CPEs that behave primarily by transcellular transport are preferred for delivering drugs into epithelial cells. CPEs that behave primarily by paracellular transport are preferred for delivering drugs through epithelial cells. Also provided herein are mucoadhesive oral dosage forms. In a preferred embodiment, the oral dosage form is a multi-compartmental device, containing (i) a supporting compartment, (ii) drug compartment and (iii) mucoadhesive compartment.

Priority: US201113264585 Applic. Date: 2011-10-14; WO2010US31047 Applic. Date: 2010-04-14; US2009-169171P Applic. Date: 2009-04-14

Inventor: WHITEHEAD KATHRYN [US]; KARR NATALIE [US]; ARORA ANUBHAV [US]; MITRAGOTRI SAMIR [US]; GUPTA VIVEK [US]


Application No.: US20130274372A1  Published: 17/Oct/2013

Title: ANTIMICROBIAL CHEMICAL COMPOSITIONS

Applicant/Assignee: BUNGE AMORPHIC SOLUTIONS LLC

Application No.: 13/448253   Filing Date: 16/Apr/2012

Abstract:

Antimicrobial chemical compositions comprise an aluminum phosphate (AlP) solid dispersed within a binding polymer, wherein one or more bioactive materials are disposed within AlP forming a bioactive-AlP complex. The complex may comprise the bioactive material chemically bonded with the AlP, physically combined with the AlP, or a combination of both. The complex may be formed according to precipitation, condensation and sol-gel methods of forming. The complex is engineered to provide a controlled delivery of the bioactive material or a constituent thereof upon exposure to moisture to give a desired level of antimicrobial resistance to a film or composite formed from the composition of at least about 30 mug/m2, and may also provide a desired degree of corrosion resistance through the release of passivating phosphate anion. Such antimicrobial chemical compositions provide an improved degree of active, long-term resistance to a broad range of micro-organisms when compared to known antimicrobial chemical compositions.

Priority:

Inventor: FOSCANTE RAYMOND E [US]


Application No.: US20130280329A1  Published: 24/Oct/2013

Title: METHODS AND COMPOSITIONS FOR RNAI-BASED CANCER TREATMENT

Applicant/Assignee: SILENSEED LTD

Application No.: 13/451231   Filing Date: 19/Apr/2012

Abstract:

The present invention generally concerns methods and compositions for treating mutated K-ras expressing cancers.

Priority:

Inventor: SHEMI AMOTZ [IL]; ZORDE KHVALEVSKY ELINA [IL]


Application No.: US20130280338A1  Published: 24/Oct/2013

Title: TAMPER RESISTANT AND DOSE-DUMPING RESISTANT PHARMACEUTICAL DOSAGE FORM

Applicant/Assignee:

Application No.: 13/864450   Filing Date: 17/Apr/2013

Abstract:

A tamper-resistant pharmaceutical dosage form comprising a pharmacologically active ingredient embedded in a prolonged release matrix, which comprises a prolonged release matrix material selected from the group consisting of nonionic acrylic polymers and waxy materials and which provides prolonged release of the pharmacologically active ingredient, resistance against solvent extraction, resistance against grinding, and resistance against dose-dumping in aqueous ethanol.

Priority: EP20120002708 Applic. Date: 2012-04-18

Inventor: WENING KLAUS [DE]; BARNSCHEID LUTZ [DE]; SCHWIER SEBASTIAN [DE]


Application No.: US20130287707A1  Published: 31/Oct/2013

Title: 6a,7,7-TRIMETHYLDECAHYDRO-1,4-METHANOCYCLOPROPA[de]NAPHTHALEN-1-OL

Applicant/Assignee: TAKASAGO INTERNATIONAL CORPORATION

Application No.: 13/866638   Filing Date: 19/Apr/2013

Abstract:

As a novel compound which is excellent in odor quality and has an odor of a very clear and strong woody note, the invention provides a compound represented by the following formula (1):

Priority: JP20120103867 Applic. Date: 2012-04-27

Inventor: ZAIZEN KYOKO [JP]; KOBAYASHI TSUYOSHI [JP]; NAGANO JUNKO [JP]; YAGUCHI YOSHIHIRO [JP]


Application No.: US20130287734A1  Published: 31/Oct/2013

Title: LIQUID FORMULATIONS OF LONG ACTING INTERFERON ALPHA CONJUGATE

Applicant/Assignee: HANMI SCIENCE CO., LTD

Application No.: 13/881976   Filing Date: 26/Oct/2011

Abstract:

Disclosed is a liquid formulation in which a long-acting INFalpha conjugate that has improved in vivo duration and stability can be stored stably for a long period of time. It comprises a stabilizer comprising a buffer, a sugar alcohol, a non-ionic surfactant and an isotonic agent. Being free of human serum albumin and other potential factors harmful to the body, the liquid formulation is free of concerns about viral infections and guarantees excellent storage stability to long-acting INFalpha conjugates.

Priority: KR20100104383 Applic. Date: 2010-10-26; WO2011KR08038 Applic. Date: 2011-10-26

Inventor: IM DAE SEONG [KR]; LEE JAE MIN [KR]; LEE JONG SOO [KR]; BAE SUNG MIN [KR]; KWON SE CHANG [KR]


Application No.: US20130287817A1  Published: 31/Oct/2013

Title: FLOWABLE IMPLANT WITH CROSSLINKABLE SURFACE MEMBRANE

Applicant/Assignee: WARSAW ORTHOPEDIC, INC

Application No.: 13/458286   Filing Date: 27/Apr/2012

Abstract:

A flowable biomedical implant for application to a bone defect to promote bone growth is provided. The flowable biomedical implant comprises a carrier matrix including a biodegradable polysaccharide and ceramic material. An impermeable membrane can be integrally formed at the surface of the carrier matrix by applying a crosslinking agent to the biodegradable polysaccharide mixed with ceramic materials.

Priority:

Inventor: DRAPEAU SUSAN J [US]; SHIMKO DANIEL A [US]


Application No.: US20130287820A1  Published: 31/Oct/2013

Title: ORAL DELIVERY VEHICLE AND MATERIAL

Applicant/Assignee: FOODSOURCE LURES CORPORATION

Application No.: 13/846993   Filing Date: 19/Mar/2013

Abstract:

Compositions for an oral delivery vehicle are described as well as methods for their manufacture and administration. The oral delivery vehicles can be made in any size or shape and can further comprise a medicament or other substance or object to be orally delivered. The vehicle can, for example, take the form of a pouch or capsule. Alternatively, a medicament or other substance to be orally delivered can be coated with the composition. In another alternative, the medicament or other substance to be orally delivered can be dispersed within a matrix of the composition. The compositions for the oral delivery vehicle are also suitable for use as an animal food or treat or use as a hunting bait or lure.

Priority: US201213457604 Applic. Date: 2012-04-27; US2008-909848 Applic. Date: 2008-05-13; WO2006US11428 Applic. Date: 2006-03-28; US2005-665703P Applic. Date: 2005-03-28

Inventor: ROGERS ED [US]; GILBERT ROY W [US]


Application No.: US20130289132A1  Published: 31/Oct/2013

Title: UV-EMITTING PHOSPHORS

Applicant/Assignee: KONINKLIJKE PHILIPS N.V

Application No.: 13/977800   Filing Date: 13/Dec/2011

Abstract:

The invention provides a wavelength converting material comprising a compound of the formula (Y1-w-x-y-zScwLaxGdyLuz)2-a(S04)3:Mea, wherein Me represents trivalent cation or a mixture of trivalent cations capable of emitting UV-C radiation, and wherein each of w, x, y and z is in the range of from 0.0 to 1.0 and w+x+y+z@1.0, and wherein 0.0005@a@0.2. The wavelength converting material may be applied in an illumination device for UV illumination, in particular for sterilization or disinfection by germicidal UV illumination.

Priority: EP20110150063 Applic. Date: 2011-01-04; WO2011IB55626 Applic. Date: 2011-12-13

Inventor: GREUEL GEORG [DE]; PLEWA JULIAN [DE]; BETTENTRUP HELGA [DE]; JUESTEL THOMAS [DE]


Application No.: US20130289133A1  Published: 31/Oct/2013

Title: METHOD FOR PRODUCING METAL OXIDE-CONTAINING PARTICLES, AND METHOD FOR PRODUCING AGGREGATES OF METAL OXIDE COLLOIDAL PARTICLES

Applicant/Assignee: NIPPON SHEET GLASS COMPANY, LIMITED

Application No.: 13/979060   Filing Date: 11/Jan/2012

Abstract:

A method for producing particles containing a metal oxide is provided, and the method includes: feeding a metal oxide sol having a pH of 7 or higher and containing metal oxide colloidal particles as dispersoids and water as a dispersion medium, into a liquid containing a solvent having a solubility in 20 DEG C. water of 0.05 g/100 ml or more and having a relative permittivity of 30 or lower (protic solvent) or of 40 or lower (aprotic solvent) at 20 DEG C., and thereby forming aggregates of the metal oxide colloidal particles in the liquid

and subjecting the aggregates to a treatment such as drying and heating, and thereby converting the aggregates into particles that are insoluble in water. By appropriately selecting the solvent, particles can be obtained in the form of flakes, fibers, spheres, and the like.

Priority: JP20110003417 Applic. Date: 2011-01-11; WO2012JP00129 Applic. Date: 2012-01-11

Inventor: DOSHITA KAZUHIRO [JP]; FURUICHI TOSHITAKA [JP]


Application No.: US20130295180A1  Published: 07/Nov/2013

Title: SALT PRODUCT

Applicant/Assignee: EMINATE LIMITED

Application No.: 13/856304   Filing Date: 03/Apr/2013

Abstract:

A method of preparing a salt product comprises the steps of: (i) providing a mixture which comprises salt dissolved in a solvent, said mixture further containing an organic material that is solid under ambient temperature conditions

and (ii) atomising said mixture and evaporating said solvent to produce a salt product comprised of particles of salt incorporating said organic material. The organic material may be a polymer such as a carbohydrate (e.g. maltodextrin or Gum Arabic). Novel salt products are disclosed which comprise hollow particles having a shell formed for individual crystallites of salt. The salt product is useful as a seasoning for food and may be used in lower amounts than conventional salt to provide the same taste. Particular advantages are obtained in the baking of bread.

Priority: GB20080007919 Applic. Date: 2008-05-01; US2010-736693 Applic. Date: 2010-12-06; WO2009GB50458 Applic. Date: 2009-05-01

Inventor: MINTER STEPHEN JOHN [GB]; MAUDE SARAH [GB]


Application No.: US20130296235A1  Published: 07/Nov/2013

Title: CONTAINER AND METHOD FOR STORING A PHARMACEUTICAL AGENT

Applicant/Assignee: BECTON, DICKINSON AND COMPANY

Application No.: 13/463509   Filing Date: 03/May/2012

Abstract:

A container and method for storing a pharmaceutical agent are provided for enhancing the storage time. The storage time of the pharmaceutical agent is improved by reducing the loss of stabilizing agents in the pharmaceutical agent. The storage container is formed from a polyolefin that includes a stabilizing agent in an amount effective to reduce or inhibit the migration of stabilizing agents in the pharmaceutical agent. The polyolefin container is formed with a fatty acid amide such as erucamide for stabilizing insulin that contains m-cresol and/or phenol as stabilizing agents for the insulin. The fatty acid amide incorporated in the container inhibits and/or reduces the rate of migration of the m-cresol and/or phenol into the polyolefin to extend the storage life of the insulin. The container can be a syringe, such as a pre-filled syringe, a storage vial or the flow path of an infusion pump.

Priority:

Inventor: ALARCON JAVIER [US]; RIGGSBEE WILLIAM [US]; HORVATH JOSHUA [US]; KOMMIREDDY DINESH [US]; PETTIS RON J [US]


Application No.: US20130296284A1  Published: 07/Nov/2013

Title: MICROEMULSION & SUB-MICRON EMULSION PROCESS & COMPOSITIONS

Applicant/Assignee: STIEFEL RESEARCH AUSTRALIA PTY LTD

Application No.: 13/873777   Filing Date: 30/Apr/2013

Abstract:

An oil in water microemulsion or sub-micron emulsion composition for dermal delivery of at least one pharmaceutically active ingredient, is provided. The composition includes an oil phase dispersed throughout a water phase, the oil phase including at least one member selected from the group consisting of an animal oil, a mineral oil, a vegetable oil, a silane member, a siloxane, an ester, a fatty acid, a fat, a halogen compound, and an alkoxylated alcohol

and at least one lipophilic surfactant, the water phase including at least one hydrophilic surfactant, water and optionally a non-surfactant amphiphilic compound, the weight ratio of the at least one hydrophilic surfactant to the at least one lipophilic surfactant being approximately 9.0:1.0 to 2.0:3.0.

Priority: US2009-457953 Applic. Date: 2009-06-25; US2005-216668 Applic. Date: 2005-08-31; US2005-670722P Applic. Date: 2005-04-12; US2004-606278P Applic. Date: 2004-08-31

Inventor: LARM MARIA GRAZIELLA [AU]; HARDING RONALD [AU]; JOHNSTON MICHAEL [AU]; ABRAM ALBERT ZORKO [AU]; VIYAYAKUMAR PREMA [US]; SUN PHOEBE [US]


Application No.: US20130302263A1  Published: 14/Nov/2013

Title: BLOCK TYPE-MODIFIED ORGANOPOLYSILOXANE, METHOD FOR USING THE ORGANOPOLYSILOXANE, COSMETIC, AND METHOD FOR PRODUCING THE ORGANOPOLYSILOXANE

Applicant/Assignee: SHIN-ETSU CHEMICAL CO., LTD

Application No.: 13/868235   Filing Date: 23/Apr/2013

Abstract:

A block type organopolysiloxane is represented by the following average composition formula (1), wherein each R1 independently represents a monovalent hydrocarbon group having 1 to 12 carbons

R2 represents any of a hydrogen atom, a monovalent hydrocarbon group having 1 to 15 carbons, and a monovalent acyl group having 2 to 7 carbons

R3 represents a hydrogen atom or a monovalent hydrocarbon group having 1 to 4 carbons

X represents a divalent hydrocarbon groups having 2 to 15 carbons

"n" represents an integer of 1 or more

"m" represents an integer of 1 or more

"s" represents an integer of 0 to 100

"t" represents an integer of 0 to 50

"z" represents an integer of 0 to 50

each R4 independently represents a hydrogen atom, a hydroxyl group, an alkoxy group, or an organic group represented by the general formula (2).

Priority: JP20120109850 Applic. Date: 2012-05-11

Inventor: MORIYA HIROYUKI [JP]


Application No.: US20130302406A1  Published: 14/Nov/2013

Title: Biomimetic Emulsions

Applicant/Assignee: NEW YORK UNIVERSITY

Application No.: 13/889083   Filing Date: 07/May/2013

Abstract:

A biomimetic system is provided for use in modeling cell-cell adhesion mechanisms comprising functionalized emulsion droplets. Further, a cell culture medium and a drug delivery system using said biomimetic system are provided.

Priority: US201261644290P Applic. Date: 2012-05-08

Inventor: BRUJIC JASNA [US]; PONTANI LEA-LAETITIA [US]


Application No.: US20130303378A1  Published: 14/Nov/2013

Title: Biocide Compositions Comprising Esters Of Ethoxylated Alcohols

Applicant/Assignee: COGNIS IP MANAGEMENT GMBH

Application No.: 13/881545   Filing Date: 24/Oct/2011

Abstract:

Suggested are biocide compositions, comprising (a) Esters of ethoxylated alcohols according to formula (I) R1CO(OCH2CH2)nOR2 (I) In which R1CO stands for a saturated or unsaturated acyl radical having 8 to 22 carbon atoms, R2 represents an alkyl radical having 1 to 10 carbon atoms, n denominates an integer of from 1 to 100, on condition that said esters exhibit an HLB value within a range of 10 to 17: (b) Biocides and optionally (c) Oil components or co-solvents and/or (d) Emulsifiers. The compositions show high solubility for biocides and improved emulsification properties.

Priority: EP20100188846 Applic. Date: 2010-10-26; WO2011EP68529 Applic. Date: 2011-10-24

Inventor: FLEUTE-SCHLACHTER INGO [DE]; MAINX HANS-GEORG [DE]; MACK SANDRA [DE]; BUSCH STEFAN [DE]


Application No.: US20130303473A1  Published: 14/Nov/2013

Title: LIQUID PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF A POSTERIOR EYE DISEASE

Applicant/Assignee: NOVALIQ GMBH

Application No.: 13/884785   Filing Date: 10/Nov/2011

Abstract:

The invention provides pharmaceutical compositions based on liquid vehicles whose density is substantially higher than that of aqueous physiological fluids. The compositions are useful as medicines in ophthalmology, in particular for the treatment of conditions affecting the posterior segment of an eye. They may be administered topically into the eye or in a minimally invasive manner by periocular injection. Preferred liquid carriers are selected from semifluorinated alkanes.

Priority: EP20100190832 Applic. Date: 2010-11-11; WO2011EP69795 Applic. Date: 2011-11-10

Inventor: WILSON CLIVE G [GB]


Application No.: US20130309303A1  Published: 21/Nov/2013

Title: Opiod Agonist Formulations with Releasable And Sequestered Antagonist

Applicant/Assignee: PURDUE PHARMA L.P

Application No.: 13/953033   Filing Date: 29/Jul/2013

Abstract:

Disclosed are oral dosage forms, comprising (i) a therapeutically effective amount of an opioid agonist

(ii) an opioid antagonist in releasable form

and (iii) a sequestered opioid antagonist which is not released when the dosage form is administered intact, and methods thereof.

Priority: US201213535605 Applic. Date: 2012-06-28; US201113043134 Applic. Date: 2011-03-08; US2002-213919 Applic. Date: 2002-08-06; US2001-310536P Applic. Date: 2001-08-06

Inventor: BREDER CHRISTOPHER [US]; WRIGHT CURTIS [US]; OSHLACK BENJAMIN [US]


Application No.: US20130316019A1  Published: 28/Nov/2013

Title: Production Process for a Stabilized Aqueous Solution of Oxidizing Chlorine and a Stabilized Aqueous Solution of Oxidizing Chlorine Produced in this Manner

Applicant/Assignee: DUEDI SRL

Application No.: 13/861739   Filing Date: 12/Apr/2013

Abstract:

A process is described for the preparation of a stabilized aqueous solution of oxidizing chlorine (anolyte). The process comprises electrolysis of an aqueous solution of sodium chloride or potassium chloride in an electrolytic cell having at least one anode compartment and one cathode compartment separated by a semi-permeable membrane to obtain an anolyte solution in the anode compartment and a catholyte solution in the cathode compartment, and the addition to the anolyte solution produced in this way of a stabilizing agent selected from the group consisting of hydrochloric acid (HCl) of 50 to 250 mg/l, sulphuric acid (H2SO4) of 50 to 350 mg/l, phosphoric acid (H3PO4) of 50 to 500 mg/l, periodic acid (HIO4) of 100 to 1000 mg/l, sodium chloride (NaCl) from 1 to 30 g/l, or any combination thereof. The stabilized anolyte solution produced with the process according to the invention has an advantage of a reduced pH value and increased redox potential value, preferably greater than 960.

Priority: IT2012TO00327 Applic. Date: 2012-04-13

Inventor: SERGIO CERRATO [IT]; DOMENICO D ANGELO [IT]; DANIELE MONTI [IT]; DANIELE TARTARO [IT]; ALBERTO VENTURELLO [IT]


Application No.: US20130317590A1  Published: 28/Nov/2013

Title: Stent And Delivery System With Reduced Chemical Degradation

Applicant/Assignee: ABBOTT CARDIOVASCULAR SYSTEMS INC

Application No.: 13/956152   Filing Date: 31/Jul/2013

Abstract:

Stents and delivery systems with reduced chemical degradation and methods of sterilizing the same are disclosed.

Priority: US201213418244 Applic. Date: 2012-03-12; US2007-804234 Applic. Date: 2007-05-16

Inventor: HUANG BIN [US]; KLEINER LOTHAR W [US]; STANKUS JOHN [US]


Application No.: US20130324950A1  Published: 05/Dec/2013

Title: TRANSDERMAL DELIVERY SYSTEM CONTAINING GALANTAMINE OR SALTS THEREOF

Applicant/Assignee: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY

Application No.: 13/985994   Filing Date: 17/Feb/2012

Abstract:

The present invention provides a transdermal delivery system, which comprises a drug-containing matrix layer comprising: galantamine or its pharmaceutically acceptable salt as an active ingredient

and a styrene-butadiene-styrene copolymer or a styrene-isoprene-styrene copolymer as an adhesive.

Priority: KR20110014530 Applic. Date: 2011-02-18; WO2012KR01186 Applic. Date: 2012-02-17

Inventor: CHOI HOO-KYUN [KR]; CHUN MYUNG-KWAN [KR]


Application No.: US20130330282A1  Published: 12/Dec/2013

Title: Spray Formulations With Reduced Clogging/Sedimentation Characteristics

Applicant/Assignee:

Application No.: 13/492007   Filing Date: 08/Jun/2012

Abstract:

Spray compositions are formulated with powders (e.g. corn starch) which improve skin feel, and also have a hydrophobically modified oxide additive (e.g. modified silica) to reduce the incidence of can/bottle clogging and sedimentation caused by the powder. The oxide is a mixed hydrophobic/hydrophilic oxide such as hydrophobicly modified fumed silica (e.g. silica dimethyl silylate). In one embodiment DEET can be delivered by such formulations.

Priority:

Inventor: TRENT JOHN S [US]


Application No.: US20130331463A1  Published: 12/Dec/2013

Title: METHOD FOR PRODUCING RUTILE TITANIUM OXIDE SOL

Applicant/Assignee: NISSAN CHEMICAL INDUSTRIES, LTD

Application No.: 13/985370   Filing Date: 15/Feb/2012

Abstract:

A method for producing a rutile titanium oxide sol having a particle diameter measured by dynamic light scattering of 5 nm to 100 nm, the method comprising: a process (a): mixing a tin oxalate aqueous solution, a titanium alkoxide, oxalic acid, a quaternary ammonium hydroxide, and water, while adjusting, per mole of titanium atoms, a proportion of tin atoms to be from 0.1 mol to 0.8 mol, a proportion of the oxalic acid to be from 0.01 mol to 5 mol, and a proportion of the quaternary ammonium hydroxide to be from 0.1 mol to 3.5 mol to prepare a titanium-containing aqueous solution having a concentration in terms of TiO2 of 0.1% by mass to 15% by mass

and a process (b): performing hydrothermal treatment on the titanium-containing aqueous solution produced in the process (a) at 100 DEG C. to 200 DEG C.

Priority: JP20110029852 Applic. Date: 2011-02-15; WO2012JP53554 Applic. Date: 2012-02-15

Inventor: MURAKAMI NATSUMI [JP]; MIYAMOTO AI [JP]; KOYAMA YOSHINARI [JP]


Application No.: US20130337044A1  Published: 19/Dec/2013

Title: MODULATION OF EFFECTOR T CELL RESPONSES BY LOCAL DEPLETION OF COMPLEMENT COMPONENT C3

Applicant/Assignee: PLS-DESIGN GMBH, HELMHOLTZ ZENTRUM MUNCHEN FORSCHUNGSZENTRUM FUR GESUNDHEIT UND UMWELT GMBH, KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN

Application No.: 13/917703   Filing Date: 14/Jun/2013

Abstract:

The invention relates to a pharmaceutical composition for the modulation of effector T cell responses made of one or more preparations and comprising a therapeutically effective dose of at least one recombinant human C3-derivative and of at least one antigen or allergen.

Priority: EP20120075059 Applic. Date: 2012-06-14

Inventor: BREDEHORST REINHARD [DE]; GRUNWALD THOMAS [DE]; OLLERT MARKUS [DE]; SCHMIDT-WEBER CARSTEN [DE]; SPILLNER EDZARD [DE]


Application No.: US20130337045A1  Published: 19/Dec/2013

Title: CONTROLLED ACTIVATION OF COMPLEMENT COMPONENTS FOR USE AS ENDOGENOUS ADJUVANT

Applicant/Assignee: PLS-DESIGN GMBH, HELMHOLTZ ZENTRUM MUNCHEN FORSCHUNGSZENTRUM FUR GESUNDHEIT UND UMWELT GMBH, KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN

Application No.: 13/917733   Filing Date: 14/Jun/2013

Abstract:

The invention relates to a pharmaceutical composition made of one or more preparation and comprising a therapeutically effective dose of at least one recombinant human C3-derivative and at least one antigen f_r vaccination.

Priority: EP20120075058 Applic. Date: 2012-06-14

Inventor: BREDEHORST REINHARD [DE]; GRUNWALD THOMAS [DE]; OLLERT MARKUS [DE]; SCHMIDT-WEBER CARSTEN [DE]; SPILLNER EDZARD [DE]


Application No.: US20130337065A1  Published: 19/Dec/2013

Title: APTAMER BIOCONJUGATE DRUG DELIVERY DEVICE

Applicant/Assignee: ECOSYNTHETIX LTD

Application No.: 13/990278   Filing Date: 02/Dec/2011

Abstract:

A delivery device for an active agent comprises nanoparticles based on a biopolymer such as starch. The delivery device may also be in the form of an aptamer-biopolymer-active agent conjugate wherein the aptamer targets the device for the treatment of specific disorders. The nanoparticles may be made by applying a high shear force in the presence of a crosslinker. The particles may be predominantly in the range of 50-150 nm and form a colloidal dispersion of crosslinked hydrogel particles in water. The biopolymer may be functionalized. The aptamer may be conjugated directly to the cross-linked biopolymers. The active agent may be a drug useful for the treatment of cancer. The delivery device survives for a period of time in the body sufficient to allow for the sustained release of a drug and for the transportation and uptake of the conjugate into targeted cells. However, the biopolymer is biocompatible and resorbable.

Priority: US2010-419106P Applic. Date: 2010-12-02; WO2011US63102 Applic. Date: 2011-12-02

Inventor: BLOEMBERGEN STEVEN [US]; MCLENNAN IAN J [CA]; JONES NATHAN [CA]; WAGNER RYAN [CA]; SHERMON AAREET GANESH [CA]; ELSAYED ABDEL RAHMAN [CA]; LIU JUEWEN [CA]


Application No.: US20130338143A1  Published: 19/Dec/2013

Title: Compositions for Transdermal Delivery of Active Agents

Applicant/Assignee: NEURODERM, LTD

Application No.: 13/885512   Filing Date: 15/Nov/2011

Abstract:

Disclosed herein are compositions that are useful in effecting the transdermal delivery of therapeutic agents. More particularly, the disclosed transdermal compositions may include a fatty alcohol (for example, octanol), a terpene (for example, limonene), and an active agent comprising an amine moiety.

Priority: US2010-413608P Applic. Date: 2010-11-15; WO2011IL00880 Applic. Date: 2011-11-15

Inventor: YACOBY-ZEEVI ORON [IL]; NEMAS MARA [IL]; ZAWOZINK EDUARDO [IL]


Application No.: US20130344152A1  Published: 26/Dec/2013

Title: PEROXIDE DISPERSIONS

Applicant/Assignee: ARKEMA INC

Application No.: 14/013196   Filing Date: 29/Aug/2013

Abstract:

The viscosity of aqueous dispersions of normally solid organic peroxides may be advantageously lowered through the use of surfactants which are polyglyceryl esters of C6-C12 fatty acids. The reduction in viscosity facilitates milling the peroxides to reduce particle size and also provides dispersions of small particle size peroxides which may be readily poured or pumped. The aqueous dispersions are useful as components of pharmaceutical, personal care, and cleaning products and the like and are effective decolorizing agents for food products, industrial products and the like.

Priority: WO2013US28492 Applic. Date: 2013-03-01; US201261660148P Applic. Date: 2012-06-15

Inventor: KOZEL THOMAS H [US]; GRAVELLE JOSEPH M [US]; BELFORD TIMOTHY [US]; SALVADOR TOMAS [US]; DESPOTOPOULOU MARINA [US]


Application No.: US20130345149A1  Published: 26/Dec/2013

Title: SILICONE-BASED OPHTHALMIC FORMULATIONS

Applicant/Assignee: ALLERGAN, INC

Application No.: 13/972070   Filing Date: 21/Aug/2013

Abstract:

Compositions, products and methods including silicone based excipients are provided. The compositions, products and methods of the present invention are particularly useful for the treatment of ophthalmic diseases.

Priority: US201213410828 Applic. Date: 2012-03-02; US201213411059 Applic. Date: 2012-03-02; US201161448899P Applic. Date: 2011-03-03; US201161529553P Applic. Date: 2011-08-31; US201161565447P Applic. Date: 2011-11-30; US201161448890P Applic. Date: 2011-03-03

Inventor: WARNER KEVIN S [US]; PARASHAR AJAY [US]


Application No.: US20130345318A1  Published: 26/Dec/2013

Title: SILICONE POLYETHERS AND PREPARATION THEREOF FROM POLYETHERS BEARING METHYLIDENE GROUPS

Applicant/Assignee: EVONIK INDUSTRIES AG

Application No.: 13/923896   Filing Date: 21/Jun/2013

Abstract:

Silicone polyethers and a process for preparation thereof wherein polyethers modified laterally with methylidene groups are reacted with hydrosiloxanes in a hydrosilylation reaction.

Priority: DE201210210553 Applic. Date: 2012-06-22

Inventor: SCHUBERT FRANK [DE]; FERENZ MICHAEL [DE]; KNOTT WILFRIED [DE]

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