US Skin Care Actives Formulation Patents Granted in 2012
US PATENTS IN ACTIVES FOR SKIN CARE GRANTED IN  2012
This list includes patents granted in the United States. The list was retrieved by searching the claims section of all patent applications published. Salient search terms include skin care
active ingredients having properties such as anti-ageing, anti-wrinkle, antioxidant, acne control benefits, skin whitening or lightening, blemish removal, etc. This category includes technology
related to the synthesis and delivery of actives such as peptides, exfoliants, α-hydroxy acids, herbals, free radical scavengers, "green" derived molecules and compounds having unique
sensory properties.
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US PATENTS IN SKIN CARE ACTIVES GRANTED IN 2012



Patent No.: US8088400B2  Issued: 03/Jan/2012

Title: Disinfectant with Quarternary Ammonium Polymer and Copolymers

Applicant/Assignee: QUICK-MED TECHNOLOGIES, INC

Application No.: 12/064487   Filing Date: 22/Aug/2006

Abstract:

An alcohol-soluble, water-insoluble, disinfectant composition and a method of using the same for disinfecting and for providing a prolonged antimicrobial property to a variety of surfaces, including skin. The composition comprises an antimicrobial polymer that is capable of imparting an antimicrobial property to a surface without the use of a metal or metal-containing compound. The composition is applied to a surface and allowed to evaporate leaving a coating of antimicrobial polymer.

Priority: US2005-710128P Applic. Date: 2005-08-22; US2006-806196P Applic. Date: 2006-06-29; WO2006US32954 Applic. Date: 2006-08-22

Inventor: TOREKI WILLIAM [US]; OLDERMAN GERALD [US]


Patent No.: US8092788B2  Issued: 10/Jan/2012

Title: Compositions and methods for topical diagnostic and therapeutic transport

Applicant/Assignee: ESSENTIA BIOSYSTEMS, INC, REVANCE THERAPEUTICS, INC

Application No.: 11/073307   Filing Date: 03/Mar/2005

Abstract:

Compositions and methods are provided that are useful for the delivery, including transdermal delivery, of biologically active agents, such as non-protein non-nucleotide therapeutics and protein-based therapeutics excluding insulin, botulinum toxins, antibody fragments, and VEGF. The compositions and methods are particularly useful for topical delivery of antifungal agents and antigenic agents suitable for immunization. Alternately, the compositions can be prepared with components useful for targeting the delivery of the compositions as well as imaging components.

Priority: US2004-550014P Applic. Date: 2004-03-03

Inventor: DAKE MICHAEL D [US]; WAUGH JACOB M [US]


Patent No.: US8101206B2  Issued: 24/Jan/2012

Title: Method of attenuating swelling or inflammation

Applicant/Assignee: FERRIS PHARMACEUTICALS, INC, SESSIONS PHARMACEUTICALS INC

Application No.: 11/541082   Filing Date: 29/Sep/2006

Abstract:

The present invention provides a method of attenuating the formation or reducing the severity of swelling and/or inflammation in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of swelling and/or inflammation.

Priority: US2006-440550 Applic. Date: 2006-05-25; US2002-175119 Applic. Date: 2002-06-19; US2001-789275 Applic. Date: 2001-02-20; US1999-326836 Applic. Date: 1999-06-07; US1998-088424P Applic. Date: 1998-06-08

Inventor: SESSIONS ROBERT W [US]; KAHN ALAN R [US]


Patent No.: US8106017B2  Issued: 31/Jan/2012

Title: Peptides for Promoting Hair Growth and Improving Wrinkle and Cosmetic Compositions Comprising the same

Applicant/Assignee: CAREGEN CO., LTD

Application No.: 12/083969   Filing Date: 24/Oct/2006

Abstract:

The present invention relates to a peptide comprising a specific amino acid sequence possessing human thymosin [beta]-4 (T[beta]4) activities and its uses. The peptide of this invention has identical or similar functions or actions to human T[beta]4 and its biological activity is almost identical to natural-occurring T[beta]4. In addition, the peptide of this invention exhibits much higher stability and skin permeation than natural-occurring T[beta]4. In these connections, the composition comprising the peptides of this invention can exhibit excellent efficacies on improvement in thymosin [beta]-4-effective disorders or conditions. In addition, the peptide of this invention can be advantageously applied to drugs, cosmetics, toothpaste and compositions for mouth cleaning and caring, most preferably, cosmetics.

Specifically, the peptide of this invention is advantageously applied to cosmetics for promoting hair growth.

Priority: KR20050100390 Applic. Date: 2005-10-24; WO2006KR04352 Applic. Date: 2006-10-24

Inventor: CHUNG YONG JI [KR]; KIM YOUNG DEUG [KR]; KIM CHUNG RYUL [KR]


Patent No.: US8114386B2  Issued: 14/Feb/2012

Title: TOPICAL INSECT REPELLENT COMPOSITION AND METHOD OF APPLICATION

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/382976   Filing Date: 12/May/2006

Abstract:

Stable, single phase, low VOC, topical insect repellent compositions containing a film-forming polymer, insect repellent, water miscible organic solvent, and water.

Priority:

Inventor: KANTNER STEVEN S [US]


Patent No.: US8114423B2  Issued: 14/Feb/2012

Title: DEODORANT COMPOSITIONS

Applicant/Assignee: E. I. DU PONT DE NEMOURS AND COMPANY

Application No.: 11/869056   Filing Date: 09/Oct/2007

Abstract:

This invention relates to deodorant compositions containing polytrimethylene ether glycol homo- and copolymers and/or polytrimethylene glycol ester(s) in a variety of physical forms. In at least one embodiment, the polytrimethylene ether glycol homo- and copolymers and/or polytrimethylene glycol ester(s) are derived predominantly from monomers (e.g., 1,3-propanediol) obtained from renewable resources, and are thus more environmentally friendly in terms of manufacture, use and disposal.

Priority:

Inventor: SUNKARA HARI BABU [US]; POLADI RAJA HARI PRASAD R [US]


Patent No.: US8124063B2  Issued: 28/Feb/2012

Title: Method for moisturizing human skin using dihydroxypropyltri(C1-C3 alkyl) ammonium salts

Applicant/Assignee: UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC, CONOPCO, INC

Application No.: 10/972483   Filing Date: 25/Oct/2004

Abstract:

A personal care product is provided which includes a composition containing dihydroxypropyltri(C1-C3 alkyl)ammonium salt in a carrier. The composition is packaged for delivery to a consumer and includes instructions printed on or associated with the packaging indicating topical use of the composition on skin, hair or the oral mucosae. Particularly useful is dihydroxypropyltrimonium chloride which operates as a humectant to moisturize both at high and low relative humidity environments.

Priority:

Inventor: HARICHIAN BIJAN [US]; MCMANUS RICHARD LOREN [US]; ROSA JOSE GUILLERMO [US]


Patent No.: US8133487B2  Issued: 13/Mar/2012

Title: SOLUBLE HETERODIMERIC CYTOKINE RECEPTOR

Applicant/Assignee: ZYMOGENETICS, INC

Application No.: 12/695069   Filing Date: 27/Jan/2010

Abstract:

The present invention provides methods of treating psoriasis in a subject (i.e., psoriasis associated with a joint disease), by administering to the subject an effective dose of a composition comprising a soluble IL-22R/IL-20RB heterodimeric polypeptide, wherein the heterodimeric polypeptide comprises an IL-22R extracellular domain covalently linked to an IL-20RB extracellular domain.

Priority: US2007-690915 Applic. Date: 2007-03-26; US2003-471151 Applic. Date: 2003-09-08; WO2002US07214 Applic. Date: 2002-03-07; US2001-274560P Applic. Date: 2001-03-09; US2001-299865P Applic. Date: 2001-06-21

Inventor: CHANDRASEKHER YASMIN A [US]; NOVAK JULIA E [US]; FOSTER DONALD C [US]; XU WENFENG [US]; JASPERS STEPHEN R [US]


Patent No.: US8148327B2  Issued: 03/Apr/2012

Title: Aldosterone induced elastin production

Applicant/Assignee: HUMAN MATRIX SCIENCES, LLC, THE HOSPITAL FOR SICK CHILDREN

Application No.: 12/157141   Filing Date: 06/Jun/2008

Abstract:

Compositions and methods for inducing the deposition of elastin in skin by administering compositions including a mineralocorticoid, such as, for example, aldosterone and, optionally, a secondary active agent for enhancing or modulating the effect of the mineralocorticoid are described herein.

Priority: US2007-942305P Applic. Date: 2007-06-06

Inventor: MITTS THOMAS [US]; HINEK ALEKSANDER [CA]


Patent No.: US8153144B2  Issued: 10/Apr/2012

Title: Stable multiphase composition comprising alkylamphoacetate

Applicant/Assignee: THE PROCTER & GAMBLE COMPANY, THE PROCTOR & GAMBLE COMPANY

Application No.: 11/710181   Filing Date: 23/Feb/2007

Abstract:

The multiphase personal care composition of the present invention comprises a first phase and a second phase. The first phase is comprised of structured surfactant phase that comprises at least about 0.5% of alkylamphoacetate. The alkylamphoacetate comprises a Percentage Diacetate of less than about 15%.

Priority: US2006-777643P Applic. Date: 2006-02-28

Inventor: BERRY JAMAL IHSAN [US]; WEI KARL SHIQING [US]; SMITH III EDWARD DEWEY [US]; SYFERT SCOTT WILLIAM [US]


Patent No.: US8163694B2  Issued: 24/Apr/2012

Title: Method of treating diseases or abnormal conditions with GDF5

Applicant/Assignee: BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA MBH

Application No.: 12/336895   Filing Date: 17/Dec/2008

Abstract:

The present invention concerns improved osteoinductive materials comprising matrix materials and morphogenetic proteins, wherein depending on the subject matter the proteins may be dimeric or monomeric proteins. The osteoinductive materials according to the present invention have improved properties. The invention further concerns methods for producing the respective improved osteoinductive materials.

Priority: EP20030007141 Applic. Date: 2003-03-28; US2005-550958 Applic. Date: 2005-09-28; WO2004EP03238 Applic. Date: 2004-03-26

Inventor: POHL JENS [DE]; BECHTOLD ROLF [DE]; KRUSE MICHAEL [DE]


Patent No.: US8178115B2  Issued: 15/May/2012

Title: Method and Composition for the Treatment of Scars

Applicant/Assignee:

Application No.: 12/892482   Filing Date: 28/Sep/2010

Abstract:

A multi-component medicament composition for the treatment of scars comprising a combination of a steroid and silicone.

Priority: US2004-829316 Applic. Date: 2004-04-21; US1999-441138 Applic. Date: 1999-11-17

Inventor: STUDIN JOEL R [US]


Patent No.: US8182833B2  Issued: 22/May/2012

Title: Method and kit for reducing the symptoms of peripheral vascular disease with topical progesterone

Applicant/Assignee: DIMERA INCORPORATED

Application No.: 12/459579   Filing Date: 02/Jul/2009

Abstract:

A method for reducing the symptoms of peripheral vascular disease and for improving peripheral circulation wherein a progestin is administered to a subject in need thereof.

Priority: US2003-348570 Applic. Date: 2003-01-21

Inventor: HERMSMEYER R KENT [US]


Patent No.: US8183204B2  Issued: 22/May/2012

Title: METHODS AND COMPOSITIONS FOR INCREASING SKIN REMODELING

Applicant/Assignee: SUMMIT ASSOCIATES INTERNATIONAL INC

Application No.: 12/169548   Filing Date: 08/Jul/2008

Abstract:

Skin remodeling is stimulated at the site of blemished skin using an ionic metal-peptide complex to diminish or remove the skin imperfection. The blemish can be a scar, especially surgical or wound scars, acne scars, keloid scars, and the like, or a skin tag, callus, benign skin mole, stretch marks, facial keratosis, thickened sunspots of the skin, or a vitiligo spot. The peptide-ionic metal complex is comprised of an ionic metal selected from copper(II), tin(II), tin(IV), and zinc(II), and salts thereof, and the peptide component can be a hydrolysis of casein, collagen, elastin, meat products, silk protein, or soybean protein, or a chemically synthesized dipeptide, tripeptide, tetrapeptide or the like which complexes with the ionic metal.

Priority: US2000-239831P Applic. Date: 2000-10-11; US2001-976646 Applic. Date: 2001-10-11

Inventor: PICKART LOREN R [US]


Patent No.: US8187576B2  Issued: 29/May/2012

Title: PLASTICIZER OF NATURAL ORIGIN FOR NAIL POLISH

Applicant/Assignee: DURLIN FRANCE

Application No.: 12/160441   Filing Date: 10/Jan/2007

Abstract:

The use of at least one carbonate of natural origin as a plasticizer in a film-forming cosmetic composition comprising, in a physiologically acceptable medium, a film-forming polymer and a solvent medium.

Priority: FR20060000248 Applic. Date: 2006-01-11; WO2007EP50214 Applic. Date: 2007-01-10

Inventor: BANDRES MATTHIEU [FR]; DESWARTVAEGHER ALAIN [FR]; DE CARO PASCALE [FR]; SENET JEAN-PIERRE [FR]; THIEBAUD ROUX SOPHIE [FR]


Patent No.: US8187881B2  Issued: 29/May/2012

Title: Methods related to wound healing

Applicant/Assignee: STEMNION, INC

Application No.: 12/592658   Filing Date: 01/Dec/2009

Abstract:

The invention is directed to methods for the treatment of wounds. Such methods utilize novel compositions, including but not limited to amnion-derived multipotent cells (herein referred to as AMP cells), conditioned media derived therefrom (herein referred to as amnion-derived cellular cytokine suspension or ACCS), cell lysates derived therefrom, cell products derived therefrom, each alone or in combination.

Priority: US2006-392892 Applic. Date: 2006-03-29; WO2006US11392 Applic. Date: 2006-03-29; US2007-724094 Applic. Date: 2007-03-14

Inventor: SMITH CHARLOTTE A [US]; TRUMPOWER CATHERINE J [US]; MARSHALL VIVIENNE S [US]


Patent No.: US8188049B2  Issued: 29/May/2012

Title: Peptides Having Activities of Epidermal Growth Factor and Its Uses

Applicant/Assignee: CAREGEN CO., LTD

Application No.: 12/444874   Filing Date: 08/Oct/2007

Abstract:

The present invention relates to peptides comprising the amino acid sequence represented by the following formula 1 and having the activities of epidermal growth factor and their uses: Cys-Met-Tyr-Ile-Glu-Linker-Arg-Gly-Asp (1) The EGF-mimicking peptides of the present invention possess identical functions or activities to natural-occurring human EGF and are able to promote the generation of autocrine EGF in cells. In addition the peptides of the present invention are much higher stability and skin penetration potency than natural-occurring EGF. Therefore, the composition containing the peptide exhibits excellent treatment and prevention efficacies on diseases or conditions demanding EGF activities, and can be advantageously applied to pharmaceutical compositions, quasi-drugs and cosmetics.

Priority: KR20060098368 Applic. Date: 2006-10-10; WO2007KR04895 Applic. Date: 2007-10-08

Inventor: CHUNG YONG-JI [KR]; KIM YOUNG DEUG [KR]; KIM EUN MI [KR]; CHOI JUN YOUNG [KR]; SONG SANG SU [KR]


Patent No.: US8188050B2  Issued: 29/May/2012

Title: PHARMACEUTICAL AND/OR COSMETIC COMPOSITION CONTAINING PEPTIDES

Applicant/Assignee: SOCIETE D'EXTRACTION DES PRINCIPES ACTIFIS SA (VINCIENCE), ISP INVESTMENTS INC

Application No.: 12/446951   Filing Date: 26/Oct/2007

Abstract:

The present invention concerns the use of peptide fragments of the protein SLC24A5 as active agents designed to induce, increase, or restore the synthesis of melanin in the melanocytes of the epidermis or of the pilar bulb, alone or in association with at least one other active agent, in a cosmetic composition or for the preparation of a pharmaceutical or particularly dermatological composition. The invention is also related to any composition containing the active agents.

Priority: FR20060009415 Applic. Date: 2006-10-26; WO2007FR01774 Applic. Date: 2007-10-26

Inventor: DAL FARRA CLAUDE [FR]; DOMLOGE NOUHA [FR]; BOTTO JEAN-MARIE [FR]


Patent No.: US8198244B2  Issued: 12/Jun/2012

Title: REGULATION OF SKIN CHARACTERISTICS BY DICKKOPF1 (DKK1)

Applicant/Assignee: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN S

Application No.: 12/518052   Filing Date: 07/Dec/2007

Abstract:

The present disclosure is generally related to methods of inducing non-palmoplantar skin to develop a palmoplantar phenotype, for example, methods for increasing skin thickness, decreasing skin pigmentation, and/or decreasing hair growth. In particular, disclosed herein are methods of using topical administration of DKK1 to increase skin thickness, decrease skin pigmentation, or reduce hair growth. Also disclosed are topical DKK1 compositions for inducing non-palmoplantar skin to develop a palmoplantar phenotype.

Priority: WO2007US86855 Applic. Date: 2007-12-07; US2006-873874P Applic. Date: 2006-12-07

Inventor: HEARING VINCENT [US]; YAMAGUCHI YUJI [JP]; PASSERON THIERRY [FR]


Patent No.: US8198344B2  Issued: 12/Jun/2012

Title: Method of preparing adhesive compositions for medical use: single additive as both the thickening agent and the accelerator

Applicant/Assignee: ADHEZION BIOMEDICAL, LLC.,, ADHEZION BIOMEDICAL, LLC

Application No.: 12/214794   Filing Date: 20/Jun/2008

Abstract:

The present invention relates to compositions of cyanoacrylate monomer, a method of improving the viscosity and the curing speed with a single additive and a process of providing sterilized cyanoacrylate adhesive compositions for application in the medical field.

Priority:

Inventor: ZHANG SHENG [US]; RUIZ RAFAEL [US]


Patent No.: US8202512B2  Issued: 19/Jun/2012

Title: METABOLIC UNCOUPLING THERAPY

Applicant/Assignee:

Application No.: 13/198289   Filing Date: 04/Aug/2011

Abstract:

A combination of chemical agents reduces reductive stress by limiting the accumulation of high-energy electrons potentially available to the electron transport chain. A method of metabolic uncoupling therapy comprises: analyzing a specific physiologic process involving reductive stress

identifying a plurality of MUT agents that modulate metabolic pathways by influencing electron flux

and formulating a combination of MUT agents that limits the accumulation of high-energy electrons potentially available to the electron transport chain.

Priority: US2007-703446 Applic. Date: 2007-02-06; US2003-462958 Applic. Date: 2003-06-17; US2000-749584 Applic. Date: 2000-12-28

Inventor: MCCLEARY EDWARD LARRY [US]


Patent No.: US8202522A1  Issued: 21/Jun/2012

Title: SKIN COSMESIS TREATMENT WITH CLOSTRIDIA NEUROTOXINS

Applicant/Assignee:

Application No.: 13/343601   Filing Date: 04/Jan/2012

Abstract:

Methods of using clostridial toxins and other biological agents to treat skin cosmesis in humans is provided. The disclosed methods provide beneficial effects in humans.

Priority: US2005-524304 Applic. Date: 2005-02-08; US2002-404378P Applic. Date: 2002-08-19; US2007-904963 Applic. Date: 2007-09-28; WO2003US25708 Applic. Date: 2003-08-18; US2010-870761 Applic. Date: 2010-08-27

Inventor: SANDERS IRA [US]; SANDERS ROSEMARY [US]


Patent No.: US8211413B2  Issued: 03/Jul/2012

Title: Method and composition for preventing coloring of the skin adjacent the hairline when dying a person's hair

Applicant/Assignee: YOU SEE, LLC

Application No.: 12/655838   Filing Date: 11/Jan/2010

Abstract:

The present invention relates to a method of dying a person's hair and especially to a method and composition for preventing coloring of the skin adjacent the hairline when dying a person's hair. The composition for applying to a person's skin adjacent the hairline to prevent coloring of the skin adjacent the hairline when dyeing a person's hair includes a mixture of alcohol, polyvinylpyrrolidone, polyvinyl alcohol, glycerin, ethylhexyl palminate, bambusa starch octenylsuccinate, zinc oxide, titanium dioxide, polythylene glycol, dimethicone, allantoin and water.

Priority:

Inventor: YOON SANG H [US]


Patent No.: US8217008B2  Issued: 10/Jul/2012

Title: Methods of treating inflammatory disease using a soluble IL-20 receptor

Applicant/Assignee: ZYMOGENETICS, INC

Application No.: 12/899700   Filing Date: 07/Oct/2010

Abstract:

A soluble receptor to IL-20 having two polypeptide subunits, IL-20RA (formerly called ZcytoR7) and IL-20RB (formerly called DIRS1). The two subunits are preferably linked together. In one embodiment one subunit is fused to the constant region of the light chain of an immunoglobulin, and the other subunit is fused to the constant region of the heavy chain of the immunoglobulin. The light chain and the heavy chain are connected via a disulfide bond.

Priority: US2009-509667 Applic. Date: 2009-07-27; US2006-458367 Applic. Date: 2006-07-18; US2000-213416P Applic. Date: 2000-06-22; US2000-745792 Applic. Date: 2000-12-22; US1999-171966P Applic. Date: 1999-12-23

Inventor: FOSTER DONALD C [US]; XU WENFENG [US]; MADDEN KAREN L [US]; KELLY JAMES D [US]; SPRECHER CINDY A [US]; BRANDT CAMERON S [US]; RIXON MARK W [US]; PRESNELL SCOTT R [US]; FOX BRIAN A [US]


Patent No.: US8231916B2  Issued: 31/Jul/2012

Title: USE OF A RICE PROTEIN HYDROLYSATE AS PIGMENTING ACTIVE PRINCIPLE

Applicant/Assignee: LABORATOIRES EXPANSCIENCE

Application No.: 12/299009   Filing Date: 18/Jul/2007

Abstract:

The present invention concerns the use of a rice protein hydrolysate in order to pigment the skin and skin appendages. Thus, it is possible to intensify the normal pigmentation of the skin without sunlight. Preferred areas of applications are repigmentation of white patches of the skin, repigmentation of white patches of the skin as a consequence of pityriasis or due to the use of dermocorticoids

acceleration and intensification of the tanning process, stimulation of the constitutive photoprotection and improvement of the phototype, prevention of skin photocarcinogenesis. Advantageously, the rice protein hydrolysate comprises peptides of which at least 50% have a molecular mass in the range of between 300 and 3,500 Da.

Priority: FR20060006780 Applic. Date: 2006-07-18; WO2007EP57441 Applic. Date: 2007-07-18

Inventor: MSIKA PHILIPPE [FR]; NAAIMI DALALE [FR]


Patent No.: US8242076B2  Issued: 14/Aug/2012

Title: POLYPEPTIDES, MATRICES, HYDROGELS AND METHODS OF USING SAME FOR TISSUE REGENERATION AND REPAIR

Applicant/Assignee: RAMOT AT TEL AVIV UNIVERSITY LTD, THE MEDICAL RESEARCH, INFRASTRUCTURE AND HEALTH SERVICES FUND OF THE TEL AVIV MEDICAL CENTER, RAMOT AT TEL-AVIV UNIVERSITY LTD

Application No.: 12/673520   Filing Date: 13/Aug/2008

Abstract:

A novel laminin polypeptide comprising the amino acid sequence set forth by SEQ ID NO:3 is disclosed. Also disclosed are compositions-of-matter comprising a polysaccharide (e.g., hyaluronic acid) and the novel laminin polypeptide

or hyaluronic acid, a laminin polypeptide and an antioxidant (e.g., superoxide dismutase), as well as matrices and hydrogels comprising same which can be used for ex vivo or in vivo tissue formation and for treatment of pathologies characterized by diseased, damaged or loss of tissue.

Priority: US2007-935487P Applic. Date: 2007-08-15; WO2008IL01120 Applic. Date: 2008-08-13

Inventor: ROCHKIND SHIMON [IL]; NEVO ZVI [IL]


Patent No.: US8252270B2  Issued: 28/Aug/2012

Title: Composition for making-up the skin comprising at least one resin, at least one block copolymer and at least one solid fatty substance, free from volatile oil

Applicant/Assignee: L'OREAL S.A

Application No.: 12/000936   Filing Date: 19/Dec/2007

Abstract:

Disclosed herein is a composition for make-up and/or care of the skin comprising a fatty phase, comprising: at least one resin of number average molecular weight less than or equal to 10,000 g/mol, selected from rosin, derivatives of rosin, and hydrocarbon resins, at least one hydrocarbon block copolymer, at least one fatty substance whose melting point is greater than 25 DEG C. chosen from waxes and pasty fatty substances, wherein said composition comprises less than 5% of volatile oil.

Priority: US2007-878419P Applic. Date: 2007-01-04; US2007-878420P Applic. Date: 2007-01-04; FR20060055650 Applic. Date: 2006-12-19; FR20060055651 Applic. Date: 2006-12-19

Inventor: JACQUES VERONIQUE [FR]; SCHWARTZ VERONIQUE [FR]; BLIN XAVIER [FR]


Patent No.: US8252274B2  Issued: 28/Aug/2012

Title: TREATMENT AND COMPOSITION FOR ACHIEVING SKIN ANTI-AGING BENEFITS BY CORNEUM PROTEASE ACTIVATION

Applicant/Assignee: MARY KAY INC, MARY KAY, INC

Application No.: 12/202924   Filing Date: 02/Sep/2008

Abstract:

Novel methods and compositions for treating aged and environmentally damaged skin are disclosed which provide improvements in the skin's visual appearance, function and clinical/biophysical properties by activating at least one proteolytic enzyme in the skin's stratum corneum. The disclosed treatment methods involve topical application of a novel cosmetic composition containing a combination of a cationic surfactant such as N,N,-dimethyldodecyl amine oxide (DMDAO), an anionic surfactant such as sodium dodecyl sulfate (SDS), or monoalkyl phosphate (MAP) and a chelating agent such as ethylene diamine tetraacetate (EDTA) to stimulate a chronic increase in the replacement rate of the skin's stratum corneum by means of corneum protease activation.

This chronic, low level stimulation is effective to induce repair and replacement of the stratum corneum, epidermis, and dermis of the skin and improvements in the appearance, function, and anti-aging properties of the skin.

Priority: US2007-624840 Applic. Date: 2007-01-19; US2002-273649 Applic. Date: 2002-12-12; US1999-357288 Applic. Date: 1999-07-20

Inventor: SCHILTZ JOHN R [US]


Patent No.: US8263046B2  Issued: 11/Sep/2012

Title: N-phenyl-N-pyridinyl-benzamides and benzenesulfonomides having cooling properties

Applicant/Assignee: GIVAUDAN S.A

Application No.: 12/090801   Filing Date: 23/Oct/2006

Abstract:

Used as cooling agents are the compounds of formula (I), wherein Y is carbonyl (C(-O)) or sulfonyl (SO2-)

and X is OCH3, CN, C(-O)NHR, C(-O)OR, or halogen

and R is hydrogen or C1-C4 alkyl.

Priority: US2005-729920P Applic. Date: 2005-10-25; WO2006CH00592 Applic. Date: 2006-10-23

Inventor: GALOPIN CHRISTOPHE C [US]; TIGANI LORI W [US]; SLACK JAY PATRICK [US]; KRAWEC PABLO VICTOR [US]; COLE LUCIENNE [US]


Patent No.: US8263057B2  Issued: 11/Sep/2012

Title: Mascara Composition Containing Shape-Memory Polymers, Gels, and Fibers

Applicant/Assignee: AVON PRODUCTS, INC

Application No.: 11/959321   Filing Date: 18/Dec/2007

Abstract:

Cosmetic compositions containing an eyelash curling or branching agent, or a skin-lifting mask or lotion. The mascara composition comprises a SMP, at least one film-forming polymer and at least one wax and leads to a make-up product with good staying power, as well as good coating and curling. The skin-lifting mask or lotion comprises a SMP, a water phase and an oil phase and leads to a make-up product with a skin-lifting effect. The invention also pertains to a process for coating eyelashes which consists of applying the composition to the eyelashes with heat.

Priority: US2006-875463P Applic. Date: 2006-12-18

Inventor: ZHENG TAO [US]


Patent No.: US8263118B2  Issued: 11/Sep/2012

Title: BIORESORBABLE FILLERS CONSTITUTED BY PHOSPHOLIPID LIPOSOMES AND HYALURONIC ACID AND/OR THE DERIVATIVES THEREOF

Applicant/Assignee: FIDIA FARMACEUTICI S.P.A

Application No.: 13/397646   Filing Date: 15/Feb/2012

Abstract:

The present invention describes a new bioresorbable filler constituted by hyaluronic acid and/or the derivatives thereof structured with/in phospholipid liposomes, which increase the residence time of the starting polymer in situ. Said fillers described herein are substantially intended to increase the soft tissues in aesthetic surgery and dermocosmetics for the correction of mild to medium defects, but because of their special characteristics they can also be used in other fields of application.

Priority: IT2005PD00146 Applic. Date: 2005-05-20; US2007-920009 Applic. Date: 2007-12-04; WO2006EP03898 Applic. Date: 2006-04-21

Inventor: CALLEGARO LANFRANCO [IT]; GALESSO DEVIS [IT]; TAGLIENTI ANNA [IT]


Patent No.: US8263654B2  Issued: 11/Sep/2012

Title: Compositions and Methods for Skin Treatment

Applicant/Assignee:

Application No.: 12/895940   Filing Date: 01/Oct/2010

Abstract:

Compositions for the treatment of the skin. The compositions reduce and/or reverse the visible appearance of skin damage. In the preferred embodiment, the composition includes Retinyl Palmitate Polypeptide

Ascorbylmethylsilanol Pectinate

Tocopheryl Polypeptide

Cholecalciferol Polypeptide

and Niacinamide Polypeptide.

Priority: US1998-022233 Applic. Date: 1998-02-11

Inventor: ERANI SIMON [US]


Patent No.: US8263666B2  Issued: 11/Sep/2012

Title: Composition in the form of an oil-in-water emulsion and uses thereof

Applicant/Assignee: L'OREAL

Application No.: 10/685505   Filing Date: 16/Oct/2003

Abstract:

Composition for topical application in the form of an oil-in-water emulsion containing an oily phase dispersed in an aqueous phase, and a hydrophilic polymer, the composition further containing (1) at least one elastomeric organopolysiloxane and (2) at least one lipophilic compound chosen from lipophilic amino acid compounds and lipophilic salicylic acid compounds. Uses thereof, including topical application to the skin, lips, hair, etc. Stabilization of certain emulsions using a lipophilic compound.

Priority: FR20020013520 Applic. Date: 2002-10-29; FR20020013521 Applic. Date: 2002-10-29; US2002-427931P Applic. Date: 2002-11-21; US2002-427928P Applic. Date: 2002-11-21

Inventor: NOEL CHRISTINE [FR]; LIVERNETTE ANNE-FRANCE [FR]


Patent No.: US8268785B2  Issued: 18/Sep/2012

Title: Use of a Pde 5 Inhibitor for Treating and Preventing Hypopigmentary Disorders

Applicant/Assignee: SWITCH BIOTECH AG

Application No.: 11/660351   Filing Date: 15/Jul/2005

Abstract:

The invention relates to the use of PDE5 inhibitors, preferably sildenafil or tadalafil, optionally in combination with a further active ingredient, for treating and/or preventing hypopigmentary disorders.

Priority: EP20040019695 Applic. Date: 2004-08-19; US2004-603069P Applic. Date: 2004-08-19; WO2005EP07747 Applic. Date: 2005-07-15

Inventor: PEUKER HEIDEMARIE [DE]


Patent No.: US8273338B2  Issued: 25/Sep/2012

Title: TREATMENT AND COMPOSITION FOR ACHIEVING SKIN ANTI-AGING BENEFITS BY CORNEUM PROTEASE ACTIVATION

Applicant/Assignee: MARY KAY INC

Application No.: 12/632554   Filing Date: 07/Dec/2009

Abstract:

Novel methods and compositions for treating aged and environmentally damaged skin are disclosed which provide improvements in the skin's visual appearance, function and clinical/biophysical properties by activating at least one proteolytic enzyme in the skin's stratum corneum. The disclosed treatment methods involve topical application of a novel cosmetic composition containing a combination of a cationic surfactant such as N,N-dimethyldodecyl amine oxide (DMDAO), an anionic surfactant such as sodium dodecyl sulfate (SDS), or monoalkyl phosphate (MAP) and a chelating agent such as ethylene diamine tetraacetate (EDTA) to stimulate a chronic increase in the replacement rate of the skin's stratum corneum by means of corneum protease activation.

This chronic, low level stimulation is effective to induce repair and replacement of the stratum corneum, epidermis, and dermis of the skin and improvements in the appearance, function, and anti-aging properties of the skin.

Priority: US2008-202924 Applic. Date: 2008-09-02; US2007-624840 Applic. Date: 2007-01-19; US2002-273649 Applic. Date: 2002-12-12; US1999-357288 Applic. Date: 1999-07-20

Inventor: SCHILTZ JOHN R [US]


Patent No.: US8273712B2  Issued: 25/Sep/2012

Title: Promoting Wound Healing by Administering a Prostaglandin E and Granulocyte-Macrophage Colony Stimulating Factor

Applicant/Assignee: MEDICAL RESEARCH COUNCIL

Application No.: 12/094322   Filing Date: 24/Nov/2006

Abstract:

A method of promoting healing of a wound in a patient, the method comprising administering to the patient (i) a prostaglandin E (PGE) or an agonist thereof and/or an agent that increases the local concentration or effect of PGE and (ii) granulocyte-macrophage colony stimulating factor (GMCSF) or a derivative thereof. Use of (i) a PGE or an agonist thereof and/or an agent that increases the local concentration or effect of PGE and (ii) GMCSF or a derivative thereof in the preparation of a medicament for promoting healing of a wound in a patient. A wound dressing, bandage or fibrin glue comprising (i) a PGE or an agonist thereof and/or an agent that increases the local concentration or effect of PGE and (ii) GMCSF or a derivative thereof.

Priority: WO2006GB04404 Applic. Date: 2006-11-24; GB20050024103 Applic. Date: 2005-11-26

Inventor: KELLY RODNEY [GB]


Patent No.: US8283314B1  Issued: 09/Oct/2012

Title: Skin care compositions

Applicant/Assignee: JAN MARINI SKIN RESEARCH, INC

Application No.: 12/167094   Filing Date: 02/Jul/2008

Abstract:

Dermatological and cosmetic compositions and methods are provided to reduce the appearance of biological and/or environmentally-caused aging.

Priority: US2007-947607P Applic. Date: 2007-07-02

Inventor: MARINI JAN [US]


Patent No.: US8287866B2  Issued: 16/Oct/2012

Title: Methods of treating IL-TIF associated inflammatory or immune diseases using antibodies against soluble zcytor 11 cytokine receptors

Applicant/Assignee: ZYMOGENETICS, INC

Application No.: 12/943181   Filing Date: 10/Nov/2010

Abstract:

Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for soluble zcytor11 receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides and antibodies can also be used to block TIF activity in vitro and in vivo, and may be used in conjunction with TIF and other cytokines to selectively stimulate the immune system. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

Priority: US2009-489236 Applic. Date: 2009-06-22; US2005-274910 Applic. Date: 2005-11-15; US2001-925055 Applic. Date: 2001-08-08; US2000-223827P Applic. Date: 2000-08-08; US2000-250876P Applic. Date: 2000-12-01

Inventor: KINDSVOGEL WAYNE R [US]; TOPOUZIS STAVROS [US]


Patent No.: US8288347B2  Issued: 16/Oct/2012

Title: Dermal Fillers Comprising Silk Fibroin Hydrogels and Uses Thereof

Applicant/Assignee: ALLERGAN, INC

Application No.: 12/906777   Filing Date: 18/Oct/2010

Abstract:

The present specification provides compositions useful as dermal fillers and methods using such compositions to treat a condition of skin.

Priority: US2010-883139 Applic. Date: 2010-09-15; US2010-764039 Applic. Date: 2010-04-20; US2009-170895P Applic. Date: 2009-04-20

Inventor: COLLETTE ADAM L [US]; HORAN REBECCA L [US]; CHEN JINGSONG [US]; ALTMAN GREGORY H [US]


Patent No.: US8298521B2  Issued: 30/Oct/2012

Title: TREATMENT FOR EYE DISORDER

Applicant/Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, CALIFORNIA INSTITUTE OF TECHNOLOGY

Application No.: 12/126100   Filing Date: 23/May/2008

Abstract:

The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any eye disorder, although in particular embodiments the individual has a thickened Bruch's membrane. An activating energy source is utilized to effect a controlled diffusion enhancement and/or degradation of Bruch's membrane that enables improved diffusional transport between the choroid and retina. The individual is administered an inactivated diffusion-enhancing molecule that becomes associated with the membrane, which is then precisely exposed to an activating energy source, such as light or ultrasound.

Priority: US2002-393505P Applic. Date: 2002-07-02; US2003-611013 Applic. Date: 2003-07-01

Inventor: SCHWARTZ DANIEL M [US]; FRASER SCOTT [US]; GRUBBS ROBERT H [US]; GALLIVAN JUSTIN P [US]; YU CHANGJUN [US]


Patent No.: US8298523B2  Issued: 30/Oct/2012

Title: COMPOSITIONS CONTAINING INTERLEUKIN-1 AND PEPTIDES

Applicant/Assignee: UNITED TECHNOLOGIES UT AG

Application No.: 13/124272   Filing Date: 07/Nov/2008

Abstract:

The present invention relates to pharmaceutical, dermatological, cosmeceutical, or cosmetic compositions comprising (a) interleukin-1 family members consisting of interleukin-1 alpha, interleukin-1 family member 5 (delta), interleukin-1 family member 6 (epsilon), interleukin-1 family member 7 (zeta), interleukin-1 family member 8 (eta), interleukin-1 family member 9, interleukin-1 family member 10 (theta), and interleukin-18

(b) a peptide of the general formula (I): Tyr-X1-X2-Phle-X3-X4-Y, wherein X1 is Gly, L-Ala or D-Ala

X2 is Gly, L-Ala or D-Ala

X3 is absent or independently Leu, Met, Iie, or Val

X4 is absent or independently Ala, Asp, Asn, Glu, Gln, Pro, Arg, Gly, Lys, Thr, or Ser

Y is absent or a sequence of 1 to 5 amino acid residues

and acceptable carriers or diluents.

Priority: WO2008EP65152 Applic. Date: 2008-11-07

Inventor: POMYTKIN IGOR ANATOLIEVICH [RU]; PETROPAVLOV IGOR ARTUROVIC [CH]


Patent No.: US8304387B2  Issued: 06/Nov/2012

Title: Therapeutic formulations of keratinocyte growth factor

Applicant/Assignee: SWEDISH ORPHAN BIOVITRUM AB (PUBL)

Application No.: 11/302033   Filing Date: 12/Dec/2005

Abstract:

The present invention provides long-term stable formulations of lyophilized keratinocyte growth factor and methods for making a lyophilized composition comprising keratinocyte growth factor.

Priority: US2004-636210P Applic. Date: 2004-12-15

Inventor: TREUHEIT MICHAEL J [US]; DHARMAVARAM VASUMATHI [US]; PURTELL JUDITH [US]; ROY SUZANNE E [US]


Patent No.: US8304392B2  Issued: 06/Nov/2012

Title: PHARMACEUTICAL AND/OR COSMETIC COMPOSITION CONTAINING AN ACTIVE PRINCIPLE ACTIVATOR OF CYTOCHROME C

Applicant/Assignee: SOCIETE D'EXTRACTION DES PRINCIPES ACTIFS S.A (ISP VINCIENCE), ISP INVESTMENTS INC

Application No.: 12/597857   Filing Date: 23/Apr/2008

Abstract:

A peptide of formula: R1-X1-X2-X3-X4-X5-R2, wherein X1 is T

S2 is L

X3 is K

X4 is T, S, K, R or no amino acid

X5 is V, A, Y, M or no amino acid

R1 represents a primary amine function of the N-terminal amino acid

and R2 represents a hydroxyl function of the C-terminal amino acid, is capable of activating cytochrome C. The peptide can be included in cosmetic and pharmaceutical compositions intended to stimulate the functions of the mitochondria and increase intracellular ATP levels. Such compositions are useful to help protect the skin from external aggression, reduce and treat skin damage caused by UV radiation and combat cutaneous signs of aging.

Priority: FR20070003057 Applic. Date: 2007-04-27; WO2008FR00578 Applic. Date: 2008-04-23

Inventor: DAL FARRA CLAUDE [FR]; DOMLOGE NOUHA [FR]; BOTTO JEAN-MARIE [FR]


Patent No.: US8314065B2  Issued: 20/Nov/2012

Title: Method of reduction of wrinkles on skin or acceleration of wound healing by applying peptides related to basic fibroblast growth factor (bFGF)

Applicant/Assignee:

Application No.: 12/764530   Filing Date: 21/Apr/2010

Abstract:

The present invention is directed to synergistic therapies for the treatment of vitiligo. Particularly, the invention is directed to a composition for the reduction of wrinkles on skin, the acceleration of wound healing, and the darkening of hair including a peptide and an acceptable carrier. The peptide may be selected from the group consisting of the peptide of SEQ. ID 1, the peptide of SEQ. ID 2, the peptide of SEQ. ID 3, the peptide of SEQ. ID 4, the peptide of SEQ. ID 5, the peptide of SEQ. ID 6, the peptide of SEQ. ID 7, and the peptide of SEQ. ID 8.

Priority: IN2005KO00847 Applic. Date: 2005-09-13; US2008-066786 Applic. Date: 2008-07-30; WO2006IN00370 Applic. Date: 2006-09-11

Inventor: RAMAIAH ABBURI [IN]


Patent No.: US8318681B2  Issued: 27/Nov/2012

Title: UTILIZATION OF PEPTIDES AS ACTIVE INGREDIENTS FOR SLIMMING

Applicant/Assignee: SOCIETE D'EXTRACTION DES PRINCIPES ACTIFS SA (VINCIENCE), ISP INVESTMENTS INC

Application No.: 13/177810   Filing Date: 07/Jul/2011

Abstract:

A method of using proteins of the SIRT family or of polypeptide or peptide fragments of SIRT proteins as an active ingredient for slimming, alone or in combination with at least one other active agent, in a cosmetic composition or for the preparation of a pharmaceutical and/or dermatological composition is described. Said peptides are intended, in particular, for treatment of cellulite and/or used to decrease, eliminate or prevent excess fat beneath the skin.

Priority: FR20060004251 Applic. Date: 2006-05-12; US2008-300597 Applic. Date: 2008-11-12; WO2007FR00803 Applic. Date: 2007-05-11

Inventor: DAL FARRA CLAUDE [US]; DOMLOGE NOUHA [FR]; BOTTO JEAN-MARIE [FR]


Patent No.: US8323648B2  Issued: 04/Dec/2012

Title: METHODS OF MODULATING AND IDENTIFYING AGENTS THAT MODULATE INTRACELLULAR CALCIUM

Applicant/Assignee: CALCIMEDICA, INC

Application No.: 12/874024   Filing Date: 01/Sep/2010

Abstract:

Methods are provided for identifying agents that modulate intracellular calcium. Also provided are methods of modulating calcium within cells and methods of identifying proteins involved in modulating intracellular calcium.

Priority: US2009-388791 Applic. Date: 2009-02-19; US2006-547720 Applic. Date: 2006-07-18; WO2004US06542 Applic. Date: 2004-03-03; US2003-451958P Applic. Date: 2003-03-04

Inventor: ROOS JACK [US]; STAUDERMAN KENNETH A [US]; VELICELEBI GONUL [US]; DIGREGORIO PAUL J [US]; OHLSEN KARI LYNN [US]


Patent No.: US8329246B2  Issued: 11/Dec/2012

Title: Oriented collagen gel

Applicant/Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

Application No.: 12/660702   Filing Date: 02/Mar/2010

Abstract:

Techniques for the production of flow-oriented collagen gels using hydrodynamics to influence the assembly of collagen fibers. Highly concentrated monomeric solutions of collagen are subjected to shear and extensional flow as they are drawn onto a substrate to induce fibrillogenesis under a high Ph buffer. The produced gel captures the flow induced ordering of molecular collagen upon fibril formation. The depositing or the induction of fibrillogenosis occurs without the application of a magnetic field to the concentration of collagen. These highly oriented 3D scaffolds are capable inducing contact guidance and guiding mammalian cell growth. The collagen fibers mimic the construction of in vivo fibers with the characteristic D-periodicity and the integrin receptors on the fibroblasts respond to this organization.

The industrial applications of three-dimensional collagen gels as a biomaterial are widespread from drug delivery to burn repair or tissue engineering system.

Priority: US2009-209239P Applic. Date: 2009-03-04

Inventor: FULLER GERALD G [US]; KIRKWOOD JOHN E [US]


Patent No.: US8329655B2  Issued: 11/Dec/2012

Title: Methods for increasing vascularization

Applicant/Assignee: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), BIOGEN IDEC MA INC

Application No.: 12/598293   Filing Date: 01/May/2008

Abstract:

Disclosed are methods of increasing vascularization in a tissue by administering a neublastin polypeptide to a mammal exhibiting impaired or inadequate blood flow in the tissue. The methods can be used to in the treatment or prevention of a disorder characterized by impaired or inadequate blood flow or to increase vascularization in an organ that has been transplanted into a subject.

Priority: US2007-915293P Applic. Date: 2007-05-01; WO2008US62265 Applic. Date: 2008-05-01

Inventor: ROSSOMANDO ANTHONY [US]; SILVESTRE JEAN-SEBASTIEN [FR]; TAMARAT RADIA [FR]


Patent No.: US8329656B2  Issued: 11/Dec/2012

Title: Use of a PDE5 inhibitor for treating and preventing hypopigmentary disorders

Applicant/Assignee: SWITCH BIOTECH AG

Application No.: 13/032318   Filing Date: 22/Feb/2011

Abstract:

The invention relates to the use of PDE5 inhibitors for treating and/or preventing hypopigmentary disorders.

Priority: EP20040019695 Applic. Date: 2004-08-19; US2007-660351 Applic. Date: 2007-07-05; WO2005EP07747 Applic. Date: 2005-07-15; US2004-603069P Applic. Date: 2004-08-19

Inventor: PEUKER HEIDMARIE [DE]


Patent No.: US8334265B2  Issued: 18/Dec/2012

Title: METHOD OF TREATMENT OF PHOTODERMATOSES

Applicant/Assignee: CLINUVEL PHAMACEUTICALS LIMITED, CLINUVEL PHARMACEUTICALS LIMITED

Application No.: 12/438990   Filing Date: 31/Aug/2007

Abstract:

This invention relates to a method for prophylactic or therapeutic treatment of photodermatoses that are caused or exacerbated by or associated with UVR exposure in a subject, particularly a human subject, which comprises the step of administering to said subject an amount of an alpha-MSH analogue effective to reduce the photosensitivity of the skin of the subject.

Priority: AU20060904745 Applic. Date: 2006-08-31; AU20070900862 Applic. Date: 2007-02-21; WO2007AU01276 Applic. Date: 2007-08-31

Inventor: WOLGEN PHILIPPE [AU]